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Citations to this article

The role of CXC chemokines in pulmonary fibrosis
Robert M. Strieter, … , Brigitte N. Gomperts, Michael P. Keane
Robert M. Strieter, … , Brigitte N. Gomperts, Michael P. Keane
Published March 1, 2007
Citation Information: J Clin Invest. 2007;117(3):549-556. https://doi.org/10.1172/JCI30562.
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The role of CXC chemokines in pulmonary fibrosis

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Abstract

The CXC chemokine family is a pleiotropic family of cytokines that are involved in promoting the trafficking of various leukocytes, in regulating angiogenesis and vascular remodeling, and in promoting the mobilization and trafficking of mesenchymal progenitor cells such as fibrocytes. These functions of CXC chemokines are important in the pathogenesis of pulmonary fibrosis and other fibroproliferative disorders. In this Review, we discuss the biology of CXC chemokine family members, specifically as it relates to their role in regulating vascular remodeling and trafficking of circulating mesenchymal progenitor cells (also known as fibrocytes) in pulmonary fibrosis.

Authors

Robert M. Strieter, Brigitte N. Gomperts, Michael P. Keane

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Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Total
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