Since the first successful transplantation of umbilical cord blood in 1988, cord blood has become an important source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Significant progress has been accompanied by challenges for scientists, ethicists, and health policy makers. With the recent recognition of the need for a national system for the collection, banking, distribution, and use of cord blood and the increasing focus on cord blood as an alternative to embryos as a source of tissue for regenerative medicine, cord blood has garnered significant attention. We review the development of cord blood banking and transplantation and then discuss the scientific and ethical issues influencing both established and investigational practices surrounding cord blood collection, banking, and use.
Joanne Kurtzberg, Anne Drapkin Lyerly, Jeremy Sugarman
Title and authors | Publication | Year |
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Perinatal Stem Cells
RR Taghizadeh, JL Sherley |
Perinatal Stem Cells | 2010 |
A great lack of knowledge regarding umbilical cord blood banking among pregnant women in Berlin, Germany
PE Palten, JW Dudenhausen |
Journal of Perinatal Medicine | 2010 |
Educating patients about the value of umbilical cord blood donation:
PL Skabla, B McGadney-Douglas, J Hampton |
Journal of the American Academy of Physician Assistants | 2010 |
Cord blood banking in France: Reorganising the national network
G Katz, A Mills |
Transfusion and Apheresis Science | 2010 |
Stem Cell Source and Outcome After Hematopoietic Stem Cell Transplantation (HSCT) in Children and Adolescents with Acute Leukemia
C Peters, JM Cornish, SH Parikh, J Kurtzberg |
Pediatric Clinics of North America | 2010 |
An Efficient Approach to Isolation and Characterization of Pre- and Postnatal Umbilical Cord Lining Stem Cells for Clinical Applications
R Gonzalez, L Griparic, M Umana, K Burgee, V Vargas, R Nasrallah, F Silva, A Patel |
Cell Transplantation | 2010 |