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Citations to this article

PPARs in atherosclerosis: the clot thickens
Antonio Castrillo, Peter Tontonoz
Antonio Castrillo, Peter Tontonoz
Published December 1, 2004
Citation Information: J Clin Invest. 2004;114(11):1538-1540. https://doi.org/10.1172/JCI23705.
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Commentary Article has an altmetric score of 3

PPARs in atherosclerosis: the clot thickens

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Abstract

Cardiovascular disease is the leading cause of morbidity and mortality in Western countries. Previous studies have highlighted the beneficial effects of PPARγ activators on cardiovascular disease; however, the role of other PPAR family members in atherosclerosis is less clear. A report in this issue of the JCI expands our understanding of PPARs in vascular biology and highlights the potential use of multiple PPAR agonists to limit lipid accumulation in macrophages.

Authors

Antonio Castrillo, Peter Tontonoz

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Total citations by year

Year: 2023 2022 2021 2020 2017 2016 2015 2014 2012 2009 2008 2007 Total
Citations: 1 1 1 1 2 1 1 1 2 2 1 1 15
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Citations to this article (15)

Title and authors Publication Year
An insight to treat cardiovascular diseases through phytochemicals targeting PPAR-α.
Sharma S, Sharma D, Dhobi M, Wang D, Tewari D
Molecular and Cellular Biochemistry 2023
KLF2 alleviates endothelial cell injury and inhibits the formation of THP‑1 macrophage‑derived foam cells by activating Nrf2 and enhancing autophagy
Tan Z, Ren H, Liu Y, Yang H, Luo Q, Deng X
Experimental and therapeutic medicine 2022
Mechanistic Insight into PPARγ and Tregs in Atherosclerotic Immune Inflammation
Gao Z, Xu X, Li Y, Sun K, Yang M, Zhang Q, Wang S, Lin Y, Lou L, Wu A, Liu W, Nie B
Frontiers in pharmacology 2021
Sparse reduced-rank regression for integrating omics data
H Hilafu, SE Safo, L Haine
BMC bioinformatics 2020
Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions
BG Durgin, OA Cherepanova, D Gomez, T Karaoli, GF Alencar, JT Butcher, YQ Zhou, MP Bendeck, BE Isakson, GK Owens, JJ Connelly
American journal of physiology. Heart and circulatory physiology 2017
PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part I: PPAR-α
L Han, WJ Shen, S Bittner, FB Kraemer, S Azhar
Future Cardiology 2017
Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease
Inzucchi SE, Viscoli CM, Young LH, Furie KL, Gorman M, Lovejoy AM, Dagogo-Jack S, Ismail-Beigi F, Korytkowski MT, Pratley RE, Schwartz GG, Kernan WN
Diabetes care 2016
Polydatin Inhibits Formation of Macrophage-Derived Foam Cells
M Wu, M Liu, G Guo, W Zhang, L Liu
Evidence-Based Complementary and Alternative Medicine 2015
A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity
W Liu, B Wang, H Ding, DW Wang, H Zeng
International journal of molecular medicine 2014
Nonhuman primates and other animal models in diabetes research.
Harwood HJ Jr, Listrani P, Wagner JD
Journal of diabetes science and technology 2012
25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages
Xu L, Shen S, Ma Y, Kim JK, Rodriguez-Agudo D, Heuman DM, Hylemon PB, Pandak WM, Ren S
American journal of physiology. Endocrinology and metabolism 2012
TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation
S Xie, YF Lee, E Kim, LM Chen, J Ni, LY Fang, S Liu, SJ Lin, JI Abe, B Berk, FM Ho, C Chang
Proceedings of the National Academy of Sciences 2009
Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate
FERREIRA AM, FERRARI MI, TROSTCHANSKY A, BATTHYANY C, SOUZA JM, ALVAREZ MN, LÓPEZ GV, BAKER PR, SCHOPFER FJ, O\u2019DONNELL V, FREEMAN BA, RUBBO H
Biochemical Journal 2009
Nuclear Receptors and Inflammatory Diseases
K Wang, YJ Wan
Experimental biology and medicine (Maywood, N.J.) 2008
Inhibition of Interleukin-1β-Induced Group IIA Secretory Phospholipase A2 Expression by Peroxisome Proliferator-Activated Receptors (PPARs) in Rat Vascular Smooth Muscle Cells: Cooperation between PPARβ and the Proto-Oncogene BCL-6
L Ravaux, C Denoyelle, C Monne, I Limon, M Raymondjean, KE Hadri
Molecular and cellular biology 2007

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