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Nicholas J. White
Published April 15, 2004
Citation Information: J Clin Invest. 2004;113(8):1084-1092. https://doi.org/10.1172/JCI21682.
Citation Information: J Clin Invest. 2004;113(8):1084-1092. https://doi.org/10.1172/JCI21682.
Abstract
Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa. The de novo emergence of resistance can be prevented by the use of antimalarial drug combinations. Artemisinin-derivative combinations are particularly effective, since they act rapidly and are well tolerated and highly effective. Widespread use of these drugs could roll back malaria.
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Nicholas J. White
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Citations to this article (784)
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Journal of Venomous Animals and Toxins | 2021 |
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Target and non-target effects of Foeniculum vulgare and Matricaria chamomilla combined extract on Culex pipiens mosquitoes
FA Al-Mekhlafi, N Abutaha, AA Al-Doaiss, LA Keridis, AI Alsayadi, RA Mohamed, MA Wadaan, KE Ibrahim, MS Al-Khalifa |
Saudi Journal of Biological Sciences | 2021 |
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Botanical candidates from Saudi Arabian flora as potential therapeutics for Plasmodium infection
S Al-Quraishy, MA Abdel-Maksoud, EM Al-Shaebi, MA Dkhil |
Saudi Journal of Biological Sciences | 2021 |
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Selection of pfcrt K76 and pfmdr1 N86 Coding Alleles after Uncomplicated Malaria Treatment by Artemether-Lumefantrine in Mali
H Maiga, A Grivoyannis, I Sagara, K Traore, OB Traore, Y Tolo, A Traore, A Bamadio, ZI Traore, K Sanogo, OK Doumbo, CV Plowe, AA Djimde |
International journal of molecular sciences | 2021 |
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Re-Envisioning Anti-Apicomplexan Parasite Drug Discovery Approaches
GW Rangel, M Llinás |
Frontiers in Cellular and Infection Microbiology | 2021 |
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Network-driven analysis of human–Plasmodium falciparum interactome: processes for malaria drug discovery and extracting in silico targets
FE Agamah, D Damena, M Skelton, A Ghansah, GK Mazandu, ER Chimusa |
Malaria Journal | 2021 |
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Short-Time Recurrences of Plasmodium vivax Malaria as a Public Health Proxy for Chloroquine-Resistance Surveillance: A Spatio-Temporal Study in the Brazilian Amazon
AA Balieiro, AM Siqueira, GC Melo, WM Monteiro, VS Sampaio, I Mueller, MV Lacerda, DA Villela |
International journal of environmental research and public health | 2021 |
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Toxicological evaluation of aqueous extract of the traditional Chinese formula Qing Hao Gan Cao
Y Li, H Zhang, S Chen, L Zhao, J Wu, P Li, G Wu, Q Wang, C Wu, H Xu |
Toxicology Research | 2021 |
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Molecular modeling and design of some β-amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives against chloroquine sensitive, 3D7 strain of Plasmodium falciparum
ZY Ibrahim, A Uzairu, GA Shallangwa, SE Abechi |
Heliyon | 2021 |
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Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites
D Dorjsuren, RT Eastman, KJ Wicht, D Jansen, DC Talley, BA Sigmon, AV Zakharov, N Roncal, AT Girvin, Y Antonova-Koch, PM Will, P Shah, H Sun, C Klumpp-Thomas, S Mok, T Yeo, S Meister, JJ Marugan, LS Ross, X Xu, DJ Maloney, A Jadhav, BT Mott, RJ Sciotti, EA Winzeler, NC Waters, RF Campbell, W Huang, A Simeonov, DA Fidock |
Scientific Reports | 2021 |
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The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds
BM Santos, BK Dias, M Nakabashi, CR Garcia |
Frontiers in microbiology | 2021 |
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The Rare, the Best: Spread of Antimalarial-Resistant Plasmodium falciparum Parasites by Anopheles Mosquito Vectors
A Berry, S Menard, SE Nsango, L Abate, D Concordet, MT Tsapi, X Iriart, PH Awono-Ambéné, B Roche, I Morlais, LA Kirkman |
Microbiology spectrum | 2021 |
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A Systematic Review of the Evidence on the Effectiveness and Cost-Effectiveness of Mass Screen-and-Treat Interventions for Malaria Control
S Kim, VN Luande, J Rocklöv, JM Carlton, Y Tozan |
The American journal of tropical medicine and hygiene | 2021 |
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Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfcrt and pfmdr1 genes in isolates from Honduras and Nicaragua, 2018-2021.
Fontecha G, Pinto A, Archaga O, Betancourth S, Escober L, Henríquez J, Valdivia HO, Montoya A, Mejía RE |
Malaria Journal | 2021 |
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Temporal evolution of the resistance genotypes of Plasmodium falciparum in isolates from Equatorial Guinea during 20 years (1999 to 2019).
Berzosa P, Molina de la Fuente I, Ta-Tang TH, González V, García L, Rodríguez-Galet A, Díaz-Regañón R, Galán R, Cerrada-Gálvez L, Ncogo P, Riloha M, Benito A |
Malaria Journal | 2021 |
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Isolation and Characterization of Mosquito-Associated Spiroplasma cantharicola from Aedes japonicus Collected in Hokkaido, Japan.
Shimooka M, Sakurai Y, Muramatsu Y, Uchida L |
Insects | 2021 |
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Vitex negundo L. Essential Oil: Odorant Binding Protein Efficiency Using Molecular Docking Approach and Studies of the Mosquito Repellent.
Okoli BJ, Ladan Z, Mtunzi F, Hosea YC |
Insects | 2021 |
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Optimal Balance of Hydrophobic Content and Degree of Polymerization Results in a Potent Membrane-Targeting Antibacterial Polymer.
Tyagi A, Mishra A |
ACS Omega | 2021 |
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Multipurpose Drugs Active Against Both Plasmodium spp. and Microorganisms: Potential Application for New Drug Development.
Endo T, Takemae H, Sharma I, Furuya T |
Frontiers in Cellular and Infection Microbiology | 2021 |
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Treating symptomatic infections and the co-evolution of virulence and drug resistance.
Alizon S |
2021 | |
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Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 and Pfcoronin molecular markers in treatment failure in Senegal
MA Diallo, MS Yade, YD Ndiaye, I Diallo, K Diongue, SA Sy, M Sy, MC Seck, M Ndiaye, B Dieye, JF Gomis, D Sow, AB Dème, AS Badiane, D Ndiaye |
Scientific Reports | 2020 |
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Elucidating the Catalytic Reaction Mechanism of Orotate Phosphoribosyltransferase by Means of X-ray Crystallography and Computational Simulations
M Roca, S Navas-Yuste, K Zinovjev, M López-Estepa, S Gómez, FJ Fernández, MC Vega, I Tuñón |
ACS Catalysis | 2020 |
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A literature review on traditional herbal medicines for malaria
M Noronha, V Pawar, A Prajapati, RB Subramanian |
South African Journal of Botany | 2020 |
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Secondary Metabolites of Medicinal Plants: Ethnopharmacological Properties, Biological Activity and Production Strategies
B Singh, RA Sharma |
2020 | |
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New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of Plasmodium Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase
PM Cheuka, L Centani, LB Arendse, S Fienberg, L Wambua, SS Renga, GA Dziwornu, M Kumar, N Lawrence, D Taylor, S Wittlin, D Coertzen, J Reader, M van der Watt, LM Birkholtz, K Chibale |
ACS Infectious Diseases | 2020 |
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Molecular Identification of Mosquito Vectors and Their Management
TK Barik |
2020 | |
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Extrachromosomal DNA amplicons in antimalarial‐resistant Plasmodium falciparum
JM McDaniels, AC Huckaby, SA Carter, S Lingeman, A Francis, M Congdon, W Santos, PK Rathod, JL Guler |
Molecular Microbiology | 2020 |
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Sequence Analysis of the K13 -Propeller Gene in Artemisinin Challenging Plasmodium falciparum Isolates from Malaria Endemic Areas of Odisha, India: A Molecular Surveillance Study
R Rana, M Ranjit, M Bal, HK Khuntia, S Pati, S Krishna, A Das |
BioMed Research International | 2020 |
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Tolerance of Gambian Plasmodium falciparum to Dihydroartemisinin and Lumefantrine Detected by Ex Vivo Parasite Survival Rate Assay
H Mbye, F Bojang, AS Jawara, B Njie, NI Mohammed, J Okebe, U DAlessandro, A Amambua-Ngwa |
Antimicrobial agents and chemotherapy | 2020 |
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Antiplasmodial activity of triterpenes isolated from the methanolic leaf extract of Combretum racemosum P. Beauv
WM Oluyemi, BB Samuel, H Kaehlig, M Zehl, S Parapini, S D'Alessandro, D Taramelli, L Krenn |
Journal of Ethnopharmacology | 2020 |
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Green Nanoparticles: Synthesis and Biomedical Applications
JK Patra, LF Fraceto, G Das, EV Campos |
2020 | |
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Synthesis, characterization, and antiplasmodial efficacy of sulfonamide‐appended [1,2,3]‐triazoles
N Batra, V Rajendran, I Wadi, A Lathwal, RK Dutta, PC Ghosh, RD Gupta, M Nath |
Journal of Heterocyclic Chemistry | 2020 |
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Disease Dispersion and Impact in the Indian Ocean World
G Campbell, EM Knoll |
2020 | |
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Molecular Design and Synthesis of Ivermectin Hybrids Targeting Hepatic and Erythrocytic Stages of Plasmodium Parasites
L Singh, D Fontinha, D Francisco, AM Mendes, M Prudêncio, K Singh |
Journal of Medicinal Chemistry | 2020 |
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An epigrammatic status of the ‘ azole ’-based antimalarial drugs
M Sharma, P Prasher |
2020 | |
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Characterization of Artemisinin Solid Dispersion in Maltodextrin and Gum Arabic by Freeze Dried and High Energy Milling Methods
Y Meliana, D Utami, M Septiyanti, ET Wulandari, M Ghozali, WK Restu, S Fahmiati, RA Lelono |
Macromolecular Symposia | 2020 |
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In silico study, synthesis, and evaluation of the antimalarial activity of hybrid dimethoxy pyrazole 1,3,5‐triazine derivatives
P Gogoi, A Shakya, SK Ghosh, N Gogoi, P Gahtori, N Singh, DR Bhattacharyya, UP Singh, HR Bhat |
Journal of Biochemical and Molecular Toxicology | 2020 |
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Modifications of histones in parasites as drug targets
M Nawaz, I Malik, M Hameed, ZH Kuthu, J Zhou |
Veterinary Parasitology | 2020 |
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AMBER force field parameters for the Zn (II) ions of the tunneling-fold enzymes GTP cyclohydrolase I and 6‐pyruvoyl tetrahydropterin synthase
A Khairallah, ÖT Bishop, V Moses |
Journal of Biomolecular Structure and Dynamics | 2020 |
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Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria
KJ Wicht, S Mok, DA Fidock |
Annual Review of Microbiology | 2020 |
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Computational Science and Its Applications – ICCSA 2020: 20th International Conference, Cagliari, Italy, July 1–4, 2020, Proceedings, Part VI
O Gervasi, B Murgante, S Misra, C Garau, I Blečić, D Taniar, BO Apduhan, AM Rocha, E Tarantino, CM Torre, Y Karaca |
2020 | |
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Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype
MR Ansbro, Z Itkin, L Chen, G Zahoranszky-Kohalmi, C Amaratunga, O Miotto, T Peryea, CV Hobbs, S Suon, JM Sá, AM Dondorp, RW van der Pluijm, TE Wellems, A Simeonov, RT Eastman |
2020 | |
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Bednets or Biotechnology: To Rescue Current Persons or Research for the Future?
DE Callies |
2020 | |
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Advanced Pharmacological Uses of Medicinal Plants and Natural Products:
A Singh, P Singh, N Bithel |
2020 | |
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Strategy and Problems for Synthesis of Antimalaria Artemisinin (Qinghaosu)
SK Sahu, PK Behera, P Choudhury, S Panda, L Rout |
ChemistrySelect | 2020 |
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Pre-Erythrocytic Vaccines against Malaria
C Marques-da-Silva, K Peissig, SP Kurup |
Human vaccines | 2020 |
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Climate Variability and Malaria over West Africa
I Diouf, BR Fonseca, C Caminade, WM Thiaw, A Deme, AP Morse, JA Ndione, AT Gaye, A Diaw, MK Ndiaye |
The American journal of tropical medicine and hygiene | 2020 |
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Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway
GM LaMonte, F Rocamora, DS Marapana, NF Gnädig, S Ottilie, MR Luth, TS Worgall, GM Goldgof, R Mohunlal, TR Kumar, JK Thompson, E Vigil, J Yang, D Hutson, T Johnson, J Huang, RM Williams, BY Zou, AL Cheung, P Kumar, TJ Egan, MC Lee, D Siegel, AF Cowman, DA Fidock, EA Winzeler |
Nature Communications | 2020 |
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Effects of combined drug treatments on Plasmodium falciparum: In vitro assays with doxycycline, ivermectin and efflux pump inhibitors
R Nodari, Y Corbett, I Varotto-Boccazzi, D Porretta, D Taramelli, S Epis, C Bandi, LH Carvalho |
PloS one | 2020 |
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Correlation between anti-malarial and anti-haemozoin activities of anti-malarial compounds
DN Tam, GM Tawfik, AE El-Qushayri, GM Mehyar, S Istanbuly, S Karimzadeh, VL Tu, R Tiwari, TV Dat, PT Nguyen, K Hirayama, NT Huy |
Malaria Journal | 2020 |
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Efficacy of dihydroartemisinin/piperaquine and artesunate monotherapy for the treatment of uncomplicated Plasmodium falciparum malaria in Central Vietnam
E Rovira-Vallbona, NV Hong, JH Kattenberg, RM Huan, NT Hien, NT Ngoc, P Guetens, NL Hieu, TT Mai, NT Duong, TT Duong, BQ Phuc, NX Xa, A Erhart, A Rosanas-Urgell |
Journal of Antimicrobial Chemotherapy | 2020 |
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Using the Ultrasensitive Alere Plasmodium falciparum Malaria Ag HRP-2™ Rapid Diagnostic Test in the Field and Clinic in Northeastern Uganda
TJ Owalla, E Okurut, G Apungia, B Ojakol, J Lema, SC Murphy, TG Egwang |
The American journal of tropical medicine and hygiene | 2020 |
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Early transmission of sensitive strain slows down emergence of drug resistance in Plasmodium vivax
MJ Ayala, DA Villela, JA Flegg |
PLoS computational biology | 2020 |
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Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria
KJ Wicht, S Mok, DA Fidock |
Annual Review of Microbiology | 2020 |
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Improved antimalarial activity of caprol-based nanostructured lipid carriers encapsulating artemether-lumefantrine for oral administration
PA Akpa, JA Ugwuoke, AA Attama, CN Ugwu, EN Ezeibe, MA Momoh, AC Echezona, FC Kenechukwu |
African health sciences | 2020 |
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An epigrammatic status of the ‘ azole ’-based antimalarial drugs
M Sharma, P Prasher |
2020 | |
|
Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype
MR Ansbro, Z Itkin, L Chen, G Zahoranszky-Kohalmi, C Amaratunga, O Miotto, T Peryea, CV Hobbs, S Suon, JM Sá, AM Dondorp, RW van der Pluijm, TE Wellems, A Simeonov, RT Eastman |
2020 | |
|
Extrachromosomal DNA amplicons in antimalarial‐resistant Plasmodium falciparum
JM McDaniels, AC Huckaby, SA Carter, S Lingeman, A Francis, M Congdon, W Santos, PK Rathod, JL Guler |
Molecular Microbiology | 2020 |
|
Tolerance of Gambian Plasmodium falciparum to Dihydroartemisinin and Lumefantrine Detected by Ex Vivo Parasite Survival Rate Assay
H Mbye, F Bojang, AS Jawara, B Njie, NI Mohammed, J Okebe, U DAlessandro, A Amambua-Ngwa |
Antimicrobial agents and chemotherapy | 2020 |
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Mosquito midgut Enterobacter cloacae and Serratia marcescens affect the fitness of adult female Anopheles gambiae s.l
LC Ezemuoka, EA Akorli, F Aboagye-Antwi, J Akorli, O Terenius |
PloS one | 2020 |
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Sequence Analysis of the K13 -Propeller Gene in Artemisinin Challenging Plasmodium falciparum Isolates from Malaria Endemic Areas of Odisha, India: A Molecular Surveillance Study
R Rana, M Ranjit, M Bal, HK Khuntia, S Pati, S Krishna, A Das |
BioMed Research International | 2020 |
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Evidence of Self-Medication with Chloroquine before Consultation for Malaria in the Southern Pacific Coast Region of Colombia
G Diaz, AM Lasso, C Murillo, LM Montenegro, DF Echeverry |
The American journal of tropical medicine and hygiene | 2019 |
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Targeting the Hexosamine Biosynthetic Pathway Prevents Plasmodium Developmental Cycle and Disease Pathology in Vertebrate Host
PS Gomes, S Tanghe, J Gallego-Delgado, L Conde, L Freire-de-Lima, AC Lima, CG Freire-de-Lima, J da Costa Lima Junior, O Moreira, P Totino, A Rodriguez, AR Todeschini, A Morrot |
Frontiers in microbiology | 2019 |
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Concurrence of CareStart™ Malaria HRP2 RDT with microscopy in population screening for Plasmodium falciparum infection in the Mount Cameroon area: predictors for RDT positivity
RN Teh, IU Sumbele, GA Nkeudem, DN Meduke, ST Ojong, HK Kimbi |
Tropical Medicine and Health | 2019 |
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Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors
M Ocan, D Akena, S Nsobya, MR Kamya, R Senono, AA Kinengyere, EA Obuku |
Malaria Journal | 2019 |
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Nano-biotechnology: a new approach to treat and prevent malaria K Rahman, SU Khan, S Fahad, MX Chang, A Abbas, WU Khan, L Rahman, ZU Haq, G Nabi, D Khan |
International Journal of Nanomedicine | 2019 |
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Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria
A Sowunmi, G Ntadom, K Akano, FO Ibironke, AI Ayede, C Agomo, OA Folarin, GO Gbotosho, C Happi, S Oguche, HU Okafor, M Meremikwu, P Agomo, W Ogala, I Watila, O Mokuolu, F Finomo, JC Ebenebe, N Jiya, J Ambe, R Wammanda, G Emechebe, W Oyibo, F Useh, T Aderoyeje, TM Dokunmu, OT Alebiosu, S Amoo, OK Basorun, OA Wewe, C Okafor, O Akpoborie, B Fatunmbi, EO Adewoye, NM Ezeigwe, A Oduola |
Infectious Diseases of Poverty | 2019 |
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Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)
J Raman, FM Kagoro, A Mabuza, G Malatje, A Reid, J Frean, KI Barnes |
Malaria Journal | 2019 |
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Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance
LE Heller, PD Roepe |
Tropical Medicine and Infectious Disease | 2019 |
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K-13 propeller gene polymorphisms isolated between 2014 and 2017 from Cameroonian Plasmodium falciparum malaria patients
CE Moukoko, F Huang, SE Nsango, LP Foko, SB Ebong, PE Eboumbou, H Yan, L Sitchueng, B Garke, L Ayong, A Ahmed |
PloS one | 2019 |
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A two-colour multiplexed lateral flow immunoassay system to differentially detect human malaria species on a single test line
J Kim, XE Cao, JL Finkelstein, WB Cárdenas, D Erickson, S Mehta |
Malaria Journal | 2019 |
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Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids
M Demiray, DJ Miller, RK Allemann |
Beilstein Journal of Organic Chemistry | 2019 |
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Prevalence of Plasmodium falciparum Pfcrt and Pfmdr1 alleles in settings with different levels of Plasmodium vivax co-endemicity in Ethiopia
E Hailemeskel, T Menberu, G Shumie, S Behaksra, W Chali, M Keffale, M Belachew, G Shitaye, H Mohammed, D Abebe, T Ashine, C Drakeley, H Mamo, B Petros, T Bousema, FG Tadesse, E Gadisa |
International Journal for Parasitology Drugs and Drug Resistance | 2019 |
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Development and Characterization of the Solvent-Assisted Active Loading Technology (SALT) for Liposomal Loading of Poorly Water-Soluble Compounds
G Pauli, WL Tang, SD Li |
Pharmaceutics | 2019 |
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Genetic Variations Associated with Drug Resistance Markers in Asymptomatic Plasmodium falciparum Infections in Myanmar
Y Zhao, Z Liu, MT Soe, L Wang, TN Soe, H Wei, A Than, PL Aung, Y Li, X Zhang, Y Hu, H Wei, Y Zhang, J Burgess, FA Siddiqui, L Menezes, Q Wang, MP Kyaw, Y Cao, L Cui |
Genes & development | 2019 |
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The genomic architecture of antimalarial drug resistance
AN Cowell, EA Winzeler |
Briefings in Functional Genomics | 2019 |
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Multicomplex-based pharmacophore modeling in conjunction with multi-target docking and molecular dynamics simulations for the identification of Pf DHFR inhibitors
A Manhas, MY Lone, PC Jha |
Journal of Biomolecular Structure and Dynamics | 2019 |
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Anti-parasitic activity of polyether ionophores
M Antoszczak, D Steverding, A Huczyński |
European Journal of Medicinal Chemistry | 2019 |
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Evaluation of Antiplasmodial Potential of C2 and C8 Modified Quinolines: in vitro and in silico Study
R Kumar, R Sharma, I Kumar, P Upadhyay, AK Dhiman, R Kumar, R Kumar, R Purohit, D Sahal, U Sharma |
Medicinal chemistry (Shāriqah (United Arab Emirates)) | 2019 |
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Genetic profiling of the Plasmodium falciparum parasite population in uncomplicated malaria from India
A Kumar, SP Singh, R Bhatt, V Singh |
Malaria Journal | 2019 |
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Modern approach of treatment on destroyable pathogenicity of malaria parasite: A review article
D Sourav, S Sabahuddin, Ahmed, AS Mohamed, IM Mohi, B Asis, M Pallab, D Shubhasis |
AFR J PHARM PHARMACO | 2019 |
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Multi-Stage and Multi-Time Scale Feedback Control of Linear Systems with Applications to Fuel Cells
V Radisavljević-Gajić, M Milanović, P Rose |
2019 | |
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Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay
JM Dziekan, H Yu, D Chen, L Dai, G Wirjanata, A Larsson, N Prabhu, RM Sobota, Z Bozdech, P Nordlund |
Science Translational Medicine | 2019 |
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Salinomycin and its derivatives – A new class of multiple-targeted “magic bullets”
M Antoszczak, A Huczyński |
European Journal of Medicinal Chemistry | 2019 |
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Recent advances in transmission-blocking drugs for malaria elimination
I Wadi, M Nath, AR Anvikar, P Singh, A Sinha |
Future Medicinal Chemistry | 2019 |
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Current Challenges in the Development of Vaccines and Drugs Against Emerging Vector-borne Diseases
K Kim |
Current medicinal chemistry | 2019 |
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Candidate microRNAs as Biomarkers in Malaria Infection: A Systematic Review
G Rangel, N Teerawattanapong, S Chamnanchanunt, T Umemura, A Pinyachat, S Wanram |
Current molecular medicine | 2019 |
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Bio-nanobactericides: an emanating class of nanoparticles towards combating multi-drug resistant pathogens
S Baker, OV Perianova |
2019 | |
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Managing Febrile Illness in Malaria-endemic Areas: Developing Novel Diagnostics Using Host Immunological Signatures as Surrogate Markers of Infection
OO Omitola, HO Mogaji, AW Taylor-Robinson |
Current immunology reviews | 2019 |
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Horizontal Cell Biology: Monitoring Global Changes of Protein Interaction States with the Proteome-Wide Cellular Thermal Shift Assay (CETSA)
L Dai, N Prabhu, LY Yu, S Bacanu, AD Ramos, P Nordlund |
Annual Review of Biochemistry | 2019 |
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Thiosemicarbazone derivatives: Design, synthesis and in vitro antimalarial activity studies
R Matsa, P Makam, M Kaushik, SL Hoti, T Kannan |
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 2019 |
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New antimalarial lanostane triterpenes from a new isolate of Egyptian Ganoderma species
AE Wahba, AK El-Sayed, AA El-Falal, EM Soliman |
Medicinal Chemistry Research | 2019 |
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Histone deacetylase inhibitors with high in vitro activities against Plasmodium falciparum isolates collected from Gabonese children and adults
E Koehne, A Kreidenweiss, RZ Manego, M McCall, G Mombo-Ngoma, MK Mackwitz, FK Hansen, J Held |
Scientific Reports | 2019 |
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Anti-malarial, cytotoxicity and molecular docking studies of quinolinyl chalcones as potential anti-malarial agent
A Hameed, S Masood, A Hameed, E Ahmed, A Sharif, MI Abdullah |
Journal of Computer-Aided Molecular Design | 2019 |
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Performance evaluation of a popular malaria RDT in Nigeria compared with microscopy
OG Ajakaye, MR Ibukunoluwa |
Journal of Parasitic Diseases | 2019 |
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Investigating the comparative effects of six artemisinin-based combination therapies on Plasmodium-induced hepatorenal toxicity
IA Edagha, AJ Ekpo, EI Edagha, JV Bassey, TP Nyong, AS Akpan, RF Obeten, AS Okon, BA Ating |
Nigerian Medical Journal : Journal of the Nigeria Medical Association | 2019 |
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Complex malaria epidemiology in an international border area between Brazil and French Guiana: challenges for elimination
da Cruz Franco V, Peiter PC, Carvajal-Cortés JJ, dos Santos Pereira R, Mendonça Gomes MD, Suárez-Mutis MC |
Tropical Medicine and Health | 2019 |
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Epidemiology, drug resistance, and pathophysiology of Plasmodium vivax malaria
KK Dayananda, RN Achur, DC Gowda |
J VECTOR DIS | 2018 |
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Epigenetics and Malaria Susceptibility/Protection: A Missing Piece of the Puzzle
C Arama, JE Quin, B Kouriba, AK Farrants, M Troye-Blomberg, OK Doumbo |
Frontiers in immunology | 2018 |
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The Repurposing of Ivermectin for Malaria: A Prospective Pharmacokinetics-Based Virtual Clinical Trials Assessment of Dosing Regimen Options
R Badhan, Z Zakaria, O Olafuyi |
Journal of Pharmaceutical Sciences | 2018 |
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Quality control of malaria microscopy reveals misdiagnosed non-falciparum species and other microscopically detectable pathogens in Senegal
MA Diallo, K Diongue, MC Seck, M Ndiaye, I Diallo, Y Diedhiou, T Ndiaye, YD Ndiaye, AS Badiane, D Ndiaye |
Annals of clinical microbiology and antimicrobials | 2018 |
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Efficacy and safety of methylene blue in the treatment of malaria: a systematic review
G Lu, M Nagbanshi, N Goldau, MM Jorge, P Meissner, A Jahn, FP Mockenhaupt, O Müller |
BMC Medicine | 2018 |
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Expanding the SAR of Nontoxic Antiplasmodial Indolyl-3-ethanone Ethers and Thioethers
MJ Lunga, RL Chisango, C Weyers, M Isaacs, D Taylor, AL Edkins, SD Khanye, HC Hoppe, CG Veale |
ChemMedChem | 2018 |
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Designing novel inhibitors against falcipain-2 of Plasmodium falciparum
Himangini, DP Pathak, V Sharma, S Kumar |
Bioorganic & Medicinal Chemistry Letters | 2018 |
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Chemical probes and drug leads from advances in synthetic planning and methodology
CJ Gerry, SL Schreiber |
Nature Reviews Drug Discovery | 2018 |
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In Vitro Sensitivity of Pyronaridine in Thai Isolates of Plasmodium falciparum
M Mungthin, K Mahotorn, P Tan-ariya, T Thita, T Ruang-areerate, N Sittichot, N Suwandittakul |
The American journal of tropical medicine and hygiene | 2018 |
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Housing type and risk of malaria among under-five children in Nigeria: evidence from the malaria indicator survey
OM Morakinyo, FM Balogun, AF Fagbamigbe |
Malaria Journal | 2018 |
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Medicinal plants used by the people of Nsukka Local Government Area, south-eastern Nigeria for the treatment of malaria: An ethnobotanical survey
UE Odoh, PF Uzor, CL Eze, TC Akunne, CM Onyegbulam, PO Osadebe |
Journal of Ethnopharmacology | 2018 |
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Nanopore sequencing of drug-resistance-associated genes in malaria parasites, Plasmodium falciparum
LR Runtuwene, JS Tuda, AE Mongan, W Makalowski, MC Frith, M Imwong, S Srisutham, LA Thi, NN Tuan, Y Eshita, R Maeda, J Yamagishi, Y Suzuki |
Scientific Reports | 2018 |
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Checks and balances? DNA replication and the cell cycle in Plasmodium
H Matthews, CW Duffy, CJ Merrick |
Parasites & vectors | 2018 |
|
Population pharmacokinetic and pharmacodynamic properties of artesunate in patients with artemisinin sensitive and resistant infections in Southern Myanmar
JP Das, MP Kyaw, MH Nyunt, K Chit, KH Aye, MM Aye, MO Karlsson, M Bergstrand, J Tarning |
Malaria Journal | 2018 |
|
Antiplasmodial imidazopyridazines: structure–activity relationship studies lead to the identification of analogues with improved solubility and hERG profiles
PM Cheuka, N Lawrence, D Taylor, S Wittlin, K Chibale |
MedChemComm | 2018 |
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Towards Malaria Elimination - A Leap Forward
S Manguin, V Dev |
2018 | |
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Fly ash supported NiO as an efficient catalyst for the synthesis of xanthene and its molecular docking study against plasmodium glutathione reductase
AV Borhade, DR Tope, SS Kushare, SV Thakare |
Research on Chemical Intermediates | 2018 |
|
Investigating Sulfoxide-to-Sulfone Conversion as a Prodrug Strategy for a Phosphatidylinositol 4-Kinase Inhibitor in a Humanized Mouse Model of Malaria
L Gibhard, M Njoroge, T Paquet, C Brunschwig, D Taylor, N Lawrence, E Abay, S Wittlin, L Wiesner, LJ Street, K Chibale, GS Basarab |
Antimicrobial agents and chemotherapy | 2018 |
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Parasite reduction ratio one day after initiation of artemisinin-based combination therapies and its relationship with parasite clearance time in acutely malarious children
K Akano, G Ntadom, C Agomo, CT Happi, OA Folarin, GO Gbotosho, O Mokuolu, F Finomo, JC Ebenebe, N Jiya, J Ambe, R Wammanda, G Emechebe, OK Basorun, OA Wewe, S Amoo, N Ezeigwe, S Oguche, B Fatunmbi, A Sowunmi |
Infectious Diseases of Poverty | 2018 |
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Plasmodium falciparum Treated with Artemisinin-based Combined Therapy Exhibits Enhanced Mutation, Heightened Cortisol and TNF-α Induction
AO Idowu, S Bhattacharyya, S Gradus, W Oyibo, Z George, C Black, J Igietseme, AA Azenabor |
International journal of medical sciences | 2018 |
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A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania
AI Marealle, DP Mbwambo, WP Mikomangwa, M Kilonzi, HJ Mlyuka, RF Mutagonda |
Malaria Journal | 2018 |
|
Farm Animals Diseases, Recent Omic Trends and New Strategies of Treatment
RE Quiroz-Castañeda |
2018 | |
|
Synthesis and anti-Plasmodium falciparum evaluation of novel pyrazolopyrimidine derivatives
FF Silveira, LM Feitosa, JC Mafra, M de Lourdes G. Ferreira, KR Rogerio, LJ Carvalho, N Boechat, LC Pinheiro |
Medicinal Chemistry Research | 2018 |
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Identification of Pf ENR inhibitors: A hybrid structure-based approach in conjunction with molecular dynamics simulations: MANHAS et al
A Manhas, A Patel, MY Lone, PK Jha, PC Jha |
Journal of Cellular Biochemistry | 2018 |
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The Kinetics of β-Hematin Crystallization Measured by Depolarized Light Scattering
O Rifaie-Graham, X Hua, N Bruns, S Balog |
Small (Weinheim an Der Bergstrasse, Germany) | 2018 |
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Evaluation of antimalarial and biochemical profiles of Abaleria® in Plasmodium berghei-infected mice
AH Adebayo, OF Yakubu, JO Popoola, LC David, G Okenze, AG Agbafor, O Okubena |
Comparative Clinical Pathology | 2018 |
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Frugal Innovation in Bioengineering for the Detection of Infectious Diseases
AK Chavali, R Ramji |
2018 | |
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Synthesis and Antimalarial Evaluation of [1, 2,3]-Triazole-Tethered Sulfonamide-Berberine Hybrids
N Batra, V Rajendran, D Agarwal, I Wadi, PC Ghosh, RD Gupta, M Nath |
ChemistrySelect | 2018 |
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Synthesis of the Polyoxygenated Cyclohexanoid Core of Bioactive Glycosides Xylosmin and Flacourtosides E and F
NR Modugu, G Mehta |
The Journal of Organic Chemistry | 2018 |
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Bioavailability and Pharmacokinetics of Dihydroartemisinin (DHA) and its Analogs—Mechanistic Studies on its ADME
UE Osonwa, M Hu |
Current Pharmacology Reports | 2018 |
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Combination drug therapy via nanocarriers against infectious diseases
P Walvekar, R Gannimani, T Govender |
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 2018 |
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GC–MS Profiling and Antimalarial Activity of Khaya grandifoliola on Plasmodium berghei –infected mice
O Okpe, US Ndidi, J Ojowu, SR Maifada, EE Etim, DA Awen, CE Ovur |
Journal of Herbs Spices & Medicinal Plants | 2018 |
|
Novel nanostructured lipid carrier for oral delivery of a poorly soluble antimalarial agent lumefantrine: characterization and pharmacokinetics evaluation
G Huang, J Liu, L Tian, S Chen |
2018 | |
|
Mathematical Model for Hepatocytic-Erythrocytic Dynamics of Malaria
TO Orwa, RW Mbogo, LS Luboobi |
International Journal of Mathematics and Mathematical Sciences | 2018 |
|
A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial Infection by Mosquito Bites and Direct Venous Inoculation
SC Murphy, ER Duke, KJ Shipman, RL Jensen, Y Fong, S Ferguson, HE Janes, K Gillespie, AM Seilie, AE Hanron, L Rinn, M Fishbaugher, T VonGoedert, E Fritzen, SH Kappe, M Chang, JC Sousa, SR Marcsisin, S Chalon, S Duparc, N Kerr, JJ Möhrle, N Andenmatten, T Rueckle, JG Kublin |
The Journal of Infectious Diseases | 2017 |
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Malaria over-diagnosis in Cameroon: diagnostic accuracy of Fluorescence and Staining Technologies (FAST) Malaria Stain and LED microscopy versus Giemsa and bright field microscopy validated by polymerase chain reaction
SM Parsel, SA Gustafson, E Friedlander, AA Shnyra, AJ Adegbulu, Y Liu, NM Parrish, SA Jamal, E Lofthus, L Ayuk, C Awasom, CJ Henry, CP McArthur |
Infectious Diseases of Poverty | 2017 |
|
Cost benefit analysis of malaria rapid diagnostic test: the perspective of Nigerian community pharmacists
IJ Ezennia, SO Nduka, OI Ekwunife |
Malaria Journal | 2017 |
|
Population dynamics of epidemic and endemic states of drug-resistance emergence in infectious diseases
D Knipl, G Röst, SM Moghadas |
PeerJ | 2017 |
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Profile of molecular mutations in pfdhfr, pfdhps, pfmdr1, and pfcrt genes of Plasmodium falciparum related to resistance to different anti-malarial drugs in the Bata District (Equatorial Guinea)
P Berzosa, A Esteban-Cantos, L García, V González, M Navarro, T Fernández, M Romay-Barja, Z Herrador, JM Rubio, P Ncogo, M Santana-Morales, B Valladares, M Riloha, A Benito |
Malaria Journal | 2017 |
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Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents
M Espinoza-Moraga, K Singh, M Njoroge, G Kaur, J Okombo, CD Kock, PJ Smith, S Wittlin, K Chibale |
Bioorganic & Medicinal Chemistry Letters | 2017 |
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Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure–Activity Relationships of Benzo[ b ]thiophene-2-carboxamides as Antimalarial Agents
M Pieroni, E Azzali, N Basilico, S Parapini, M Zolkiewski, C Beato, G Annunziato, A Bruno, F Vacondio, G Costantino |
Journal of Medicinal Chemistry | 2017 |
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Does antimalarial mass drug administration increase or decrease the risk of resistance?
NJ White |
The Lancet Infectious Diseases | 2017 |
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Synthesis and Activity of Nucleoside-Based Antiprotozoan Compounds
HA Tran, Z Zheng, X Wen, S Manivannan, A Pastor, M Kaiser, R Brun, FF Snyder, TG Back |
Bioorganic & Medicinal Chemistry | 2017 |
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High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations
YD Ndiaye, CK Diédhiou, AK Bei, B Dieye, A Mbaye, NP Mze, RF Daniels, IM Ndiaye, AB Déme, A Gaye, M Sy, T Ndiaye, AS Badiane, M Ndiaye, Z Premji, DF Wirth, S Mboup, D Krogstad, SK Volkman, AD Ahouidi, D Ndiaye |
Malaria Journal | 2017 |
|
Private sector opportunities and threats to achieving malaria elimination in the Greater Mekong Subregion: results from malaria outlet surveys in Cambodia, the Lao PDR, Myanmar, and Thailand
S Phok, S Phanalasy, ST Thein, A Likhitsup |
Malaria Journal | 2017 |
|
Population coverage of artemisinin-based combination treatment in children younger than 5 years with fever and Plasmodium falciparum infection in Africa, 2003–2015: a modelling study using data from national surveys
A Bennett, D Bisanzio, JO Yukich, B Mappin, CA Fergus, M Lynch, RE Cibulskis, S Bhatt, DJ Weiss, E Cameron, PW Gething, TP Eisele |
The Lancet Global Health | 2017 |
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Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens
R Subramani, M Narayanasamy, KD Feussner |
3 Biotech | 2017 |
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Vector control with driving Y chromosomes: modelling the evolution of resistance
A Beaghton, PJ Beaghton, A Burt |
Malaria Journal | 2017 |
|
Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
R Ataide, EA Ashley, R Powell, JA Chan, MJ Malloy, K OFlaherty, E Takashima, C Langer, T Tsuboi, AM Dondorp, NP Day, M Dhorda, RM Fairhurst, P Lim, C Amaratunga, S Pukrittayakamee, TT Hien, Y Htut, M Mayxay, MA Faiz, JG Beeson, F Nosten, JA Simpson, NJ White, FJ Fowkes |
Proceedings of the National Academy of Sciences | 2017 |
|
Drug Resistance in Bacteria, Fungi, Malaria, and Cancer
G Arora, A Sajid, VC Kalia |
Drug Resistance in Bacteria, Fungi, Malaria, and Cancer | 2017 |
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Synthesis, antimalarial activity in vitro , and docking studies of novel neolignan derivatives
GA Pereira, GC Souza, LS Santos, LE Barata, CC Meneses, AU Krettli, CT Daniel-Ribeiro, CN Alves |
Chemical Biology & Drug Design | 2017 |
|
A new procyanidin B from Campylospermum zenkeri (Ochnaceae) and antiplasmodial activity of two derivatives of (±)-serotobenine
NM Nyemeck, DS Bikobo, AA Zintchem, EM Schäfer, C Bochet, DE Pegnyemb, U Koert |
Natural Product Research | 2017 |
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Synthesis, characterization, molecular docking and in vitro antimalarial properties of new carboxamides bearing sulphonamide
DI Ugwu, UC Okoro, PO Ukoha, S Okafor, A Ibezim, NM Kumar |
European Journal of Medicinal Chemistry | 2017 |
|
Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic
B Blasco, D Leroy, DA Fidock |
Nature Medicine | 2017 |
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Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study
TO Apinjoh, RN Mugri, O Miotto, HF Chi, RB Tata, JK Anchang-Kimbi, EM Fon, DA Tangoh, RV Nyingchu, C Jacob, R Amato, A Djimde, D Kwiatkowski, EA Achidi, A Amambua-Ngwa |
Infectious Diseases of Poverty | 2017 |
|
Household beliefs about malaria testing and treatment in Western Kenya: the role of health worker adherence to malaria test results
I Saran, EM Maffioli, D Menya, WP OMeara |
Malaria Journal | 2017 |
|
Population Pharmacokinetic and Pharmacodynamic Modeling of Artemisinin Resistance in Southeast Asia
JL Das, AM Dondorp, F Nosten, AP Phyo, W Hanpithakpong, P Ringwald, P Lim, NJ White, MO Karlsson, M Bergstrand, J Tarning |
The AAPS Journal | 2017 |
|
Recent advances in use of silver nanoparticles as antimalarial agents
M Rai, AP Ingle, P Paralikar, I Gupta, S Medici, CA Santos |
International Journal of Pharmaceutics | 2017 |
|
Development of a Rapidly Dissolvable Oral Pediatric Formulation for Mefloquine Using Liposomes
WL Tang, WH Tang, WC Chen, C Diako, CF Ross, SD Li |
Molecular Pharmaceutics | 2017 |
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The Impact of Antimalarial Use on the Emergence and Transmission of Plasmodium falciparum Resistance: A Scoping Review of Mathematical Models
A Brock, C Gibbs, J Ross, A Esterman |
Tropical Medicine and Infectious Disease | 2017 |
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Antimicrobial Drug Resistance
DL Mayers, JD Sobel, M Ouellette, KS Kaye, D Marchaim |
Antimicrobial Drug Resistance | 2017 |
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Interconvertible geometric isomers of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors exhibit multiple binding modes
GA McConkey, PT Bedingfield, DR Burrell, NC Chambers, F Cunningham, TJ Prior, CW Fishwick, AN Boa |
Bioorganic & Medicinal Chemistry Letters | 2017 |
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Investigation of the component in Artemisia annua L. leading to enhanced antiplasmodial potency of artemisinin via regulation of its metabolism
TY Cai, YR Zhang, JB Ji, J Xing |
Journal of Ethnopharmacology | 2017 |
|
Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
R Ataide, EA Ashley, R Powell, JA Chan, MJ Malloy, K OFlaherty, E Takashima, C Langer, T Tsuboi, AM Dondorp, NP Day, M Dhorda, RM Fairhurst, P Lim, C Amaratunga, S Pukrittayakamee, TT Hien, Y Htut, M Mayxay, MA Faiz, JG Beeson, F Nosten, JA Simpson, NJ White, FJ Fowkes |
Proceedings of the National Academy of Sciences | 2017 |
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Combating multidrug-resistant Plasmodium falciparum malaria
AM Thu, AP Phyo, J Landier, DM Parker, FH Nosten |
FEBS Journal | 2017 |
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An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde
M Demiray, X Tang, T Wirth, JA Faraldos, RK Allemann |
Angewandte Chemie (International ed. in English) | 2017 |
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Are Antimalarial Hybrid Molecules a Close Reality or a Distant Dream?
D Agarwal, RD Gupta, SK Awasthi |
Antimicrobial agents and chemotherapy | 2017 |
|
Population coverage of artemisinin-based combination treatment in children younger than 5 years with fever and Plasmodium falciparum infection in Africa, 2003–2015: a modelling study using data from national surveys
A Bennett, D Bisanzio, JO Yukich, B Mappin, CA Fergus, M Lynch, RE Cibulskis, S Bhatt, DJ Weiss, E Cameron, PW Gething, TP Eisele |
The Lancet Global Health | 2017 |
|
Molecular Epidemiology of Plasmodium falciparum kelch13 Mutations in Senegal Determined by Using Targeted Amplicon Deep Sequencing
E Talundzic, YD Ndiaye, AB Deme, C Olsen, DS Patel, S Biliya, R Daniels, FO Vannberg, SK Volkman, V Udhayakumar, D Ndiaye |
Antimicrobial agents and chemotherapy | 2017 |
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Combating multidrug-resistant Plasmodium falciparum malaria
AM Thu, AP Phyo, J Landier, DM Parker, FH Nosten |
FEBS Journal | 2017 |
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Altered life history strategies protect malaria parasites against drugs
PL Birget, MA Greischar, SE Reece, N Mideo |
Evolutionary Applications | 2017 |
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Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targets
RM Mogire, HM Akala, RW Macharia, DW Juma, AC Cheruiyot, B Andagalu, ML Brown, HA El-Shemy, SG Nyanjom, SA Ralph |
PloS one | 2017 |
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Diagnostic potential of monoclonal antibodies developed against C-terminal polypeptide of P. falciparum Histidine Rich Protein2 (P f HRP2) in malaria infected patients from India
R Verma, S Chandy, NS Jayaprakash, A Manoharan, MA Vijayalakshmi, K Venkataraman |
Pathogens and Global Health | 2017 |
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Intravenous human serum albumin (HSA)-bound artemether nanoparticles for treatment of severe malaria
Y Boateng-Marfo, Y Dong, ZH Loh, H Lin, WK Ng |
Colloids and Surfaces A Physicochemical and Engineering Aspects | 2017 |
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Diagnostic potential of monoclonal antibodies developed against C-terminal polypeptide of P. falciparum Histidine Rich Protein2 (P f HRP2) in malaria infected patients from India
R Verma, S Chandy, NS Jayaprakash, A Manoharan, MA Vijayalakshmi, K Venkataraman |
Pathogens and Global Health | 2017 |
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Physicochemical investigation and in vivo activity of anti-malarial drugs co-loaded in Tween 80 niosomes
M Thakkar, S Brijesh |
Journal of Liposome Research | 2017 |
|
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold
E Sandoval, MJ Lafuente-Monasterio, MJ Almela, P Castañeda, MB Díaz, MS Martínez-Martínez, J Vidal, Í Angulo-Barturen, P Bamborough, J Burrows, N Cammack, MJ Chaparro, JM Coterón, C Cozar, B Crespo, B Díaz, G Drewes, E Fernández, S Ferrer-Bazaga, MT Fraile, FJ Gamo, S Ghidelli-Disse, R Gómez, J Haselden, S Huss, ML León, J Mercado, SJ Macdonald, JI Hernando, S Prats, M Puente, A Rodríguez, JC de la Rosa, L Rueda, C Selenski, P Willis, DM Wilson, M Witty, F Calderón |
Journal of Medicinal Chemistry | 2017 |
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Predictors of antimalarial self-medication in illegal gold miners in French Guiana: a pathway towards artemisinin resistance
M Douine, Y Lazrek, D Blanchet, S Pelleau, R Chanlin, F Corlin, L Hureau, B Volney, H Hiwat, S Vreden, F Djossou, M Demar, M Nacher, L Musset |
Journal of Antimicrobial Chemotherapy | 2017 |
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Impact of chrysosplenetin, per se or in combination with artemisinin, on breast cancer resistance protein (Bcrp)/ABCG2 mRNA expression levels in mice small intestine
W Ma, Y Zhang, Y Zhang, C Zhang, J Wang, L Ma, B Yang, X Wu, J Chen |
Revista Brasileira de Farmacognosia | 2017 |
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The role of antimalarial quality in the emergence and transmission of resistance
AR Brock, JV Ross, S Parikh, A Esterman |
Medical Hypotheses | 2017 |
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Antimalarial Drug Resistance: A Threat to Malaria Elimination
D Menard, A Dondorp |
Cold Spring Harbor Perspectives in Medicine | 2017 |
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Structure and Molecular Dynamic Regulation of FKBP35 from Plasmodium knowlesi by Structural Homology Modeling and Electron Microscopy
J Silvester, HU Linda, LP Chin, LT Ying, C Budiman |
Journal of Biological Sciences | 2017 |
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Molecular Mechanism of Drug Resistance
Ray S, Das S, Suar M |
Drug Resistance in Bacteria, Fungi, Malaria, and Cancer | 2017 |
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Combating malaria with nanotechnology-based targeted and combinatorial drug delivery strategies
M Thakkar, B S. |
Drug Delivery and Translational Research | 2016 |
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Molecular Farming in Artemisia annua, a Promising Approach to Improve Anti-malarial Drug Production
G Pulice, S Pelaz, L Matías-Hernández |
Frontiers in Plant Science | 2016 |
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Tying malaria and microRNAs: from the biology to future diagnostic perspectives
M Rubio, Q Bassat, X Estivill, A Mayor |
Malaria Journal | 2016 |
|
Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introduction
GR Awab, M Imwong, S Pukrittayakamee, F Alim, W Hanpithakpong, J Tarning, AM Dondorp, NP Day, NJ White, CJ Woodrow |
Malaria Journal | 2016 |
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In Silico Characterization of the Binding Affinity of Dendrimers to Penicillin-Binding Proteins (PBPs): Can PBPs be Potential Targets for Antibacterial Dendrimers?
S Ahmed, SB Vepuri, M Ramesh, R Kalhapure, N Suleman, T Govender |
Applied Biochemistry and Biotechnology | 2016 |
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Polyvalent effect enhances diglycosidic antiplasmodial activity
WQ Zhang, Y He, Q Yu, HP Liu, DM Wang, XB Li, J Luo, X Meng, HJ Qin, NW Lucchi, V Udhayakumar, SS Iyer, Y Yang, P Yu |
European Journal of Medicinal Chemistry | 2016 |
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New Potential Antimalarial Agents: Design, Synthesis and Biological Evaluation of Some Novel Quinoline Derivatives as Antimalarial Agents
I Radini, T Elsheikh, E El-Telbani, R Khidre |
Molecules (Basel, Switzerland) | 2016 |
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The identification of FERM domain protein in serum infected with Plasmodium berghei
V P.G., KM P. |
EuPA Open Proteomics | 2016 |
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Echecs thérapeutiques multiples et successifs chez un patient infecté par Plasmodium falciparum au Cambodge et traité par dihydroartémisinine-pipéraquine
B Witkowski, N Khim, S Kim, A Domergue, V Duru, D Menard |
Bulletin de la Société de pathologie exotique | 2016 |
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Convergence Properties of Crystal Structure Prediction by Quasi-Random Sampling
DH Case, JE Campbell, PJ Bygrave, GM Day |
Journal of Chemical Theory and Computation | 2016 |
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Design, synthesis and anti-P. falciparum activity of pyrazolopyridine–sulfonamide derivatives
TB Silva, AM Bernardino, ML Ferreira, KR Rogerio, LJ Carvalho, N Boechat, LC Pinheiro |
Bioorganic & Medicinal Chemistry | 2016 |
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Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study
NY Boadu, J Amuasi, D Ansong, E Einsiedel, D Menon, SK Yanow |
Malaria Journal | 2016 |
|
Joint modeling of Anaemia and Malaria in children under five in Nigeria
SB Adebayo, E Gayawan, C Heumann, C Seiler |
Spatial and Spatio-temporal Epidemiology | 2016 |
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Molecular markers associated with resistance to commonly used antimalarial drugs among Plasmodium falciparum isolates from a malaria-endemic area in Taiz governorate—Yemen during the transmission season
LM Alareqi, MA Mahdy, YL Lau, MY Fong, R Abdul-Ghani, R Mahmud |
Acta Tropica | 2016 |
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Population pharmacokinetic properties of artemisinin in healthy male Vietnamese volunteers
S Birgersson, PV Toi, NT Truong, NT Dung, M Ashton, TT Hien, A Abelö, J Tarning |
Malaria Journal | 2016 |
|
Hemozoin detection may provide an inexpensive, sensitive, 1-minute malaria test that could revolutionize malaria screening
BT Grimberg, KO Grimberg |
Expert Review of Anti-infective Therapy | 2016 |
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From one Nobel Prize (P. Ehrlich) to another (Tu Youyou): 100 years of chemotherapy of infectious diseases
ZI Cabantchik, H Drakesmith |
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2016 |
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Resisting resistance: is there a solution for malaria?
BK Verlinden, A Louw, LM Birkholtz |
Expert Opinion on Drug Discovery | 2016 |
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Anti-malarial Drug Design by Targeting Apicoplasts: New Perspectives
GC Sadhukhan, A Mukherjee |
Journal of Pharmacopuncture | 2016 |
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The threat of antimalarial drug resistance
B Hanboonkunupakarn, NJ White |
Tropical Diseases, Travel Medicine and Vaccines | 2016 |
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Different patterns of pfcrt and pfmdr1 polymorphism in Plasmodium falciparum isolates from Tehama region, Yemen
WM Atroosh, HM Al-Mekhlafi, A Al-Jasari, H Sady, SS Dawaki, FN Elyana, MA Al-Areeqi, NA Nasr, AM Abdulsalam, LR Subramaniam, M Azzani, I Ithoi, YL Lau, J Surin |
PeerJ | 2016 |
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Anti-parasitic Peptides from Arthropods and their Application in Drug Therapy
AF Lacerda, PB Pelegrini, DM de Oliveira, ÉA Vasconcelos, MF Grossi-de-Sá |
Frontiers in microbiology | 2016 |
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Genetically Determined Response to Artemisinin Treatment in Western Kenyan Plasmodium falciparum Parasites
LJ Chebon, BS Ngalah, LA Ingasia, DW Juma, P Muiruri, J Cheruiyot, B Opot, E Mbuba, M Imbuga, HM Akala, W Bulimo, B Andagalu, E Kamau, G Langsley |
PloS one | 2016 |
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Antimalarial Activity of Small-Molecule Benzothiazole Hydrazones
S Sarkar, AA Siddiqui, SJ Saha, R De, S Mazumder, C Banerjee, MS Iqbal, S Nag, S Adhikari, U Bandyopadhyay |
Antimicrobial agents and chemotherapy | 2016 |
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Evaluation of anti-malarial drugs' use in Fitche Hospital, North Shoa, Oromia Region, Ethiopia
R Getachew, W Amelo, EM Bobasa |
Journal of Pharmacy & Bioallied Sciences | 2016 |
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In Vitro and In Vivo Pharmacokinetics of Aminoalkylated Diarylpropanes NP085 and NP102
L Gibhard, K Pravin, E Abay, A Wilhelm, K Swart, N Lawrence, R Khoury, J der Westhuizen, P Smith, L Wiesner |
Antimicrobial agents and chemotherapy | 2016 |
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Coumarin–chalcone hybrids: promising agents with diverse pharmacological properties
H Wei, J Ruan, X Zhang |
RSC Advances | 2016 |
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Asymmetric synthesis of dihydroartemisinic acid through intramolecular Stetter reaction
RK Rej, RK Acharyya, S Nanda |
Tetrahedron | 2016 |
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Antimalarial qinghaosu/artemisinin: The therapy worthy of a Nobel Prize
J Krungkrai, SR Krungkrai |
Asian Pacific Journal of Tropical Biomedicine | 2016 |
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Chrysosplenetin inhibits artemisinin efflux in P-gp-over-expressing Caco-2 cells and reverses P-gp/MDR1 mRNA up-regulated expression induced by artemisinin in mouse small intestine
L Ma, S Wei, B Yang, W Ma, X Wu, H Ji, H Sui, J Chen |
Pharmaceutical Biology | 2016 |
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Advances in Malaria Research
D Gaur, CE Chitnis, VS Chauhan |
Advances in Malaria Research | 2016 |
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Kala Azar in South Asia
E Noiri, TK Jha |
Kala Azar in South Asia | 2016 |
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Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways
KS Wang, J Li, Z Wang, C Mi, J Ma, LX Piao, GH Xu, X Li, X Jin |
Immunopharmacology and Immunotoxicology | 2016 |
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Highly Sensitive and Selective Aptamer-Based Fluorescence Detection of a Malarial Biomarker Using Single-Layer MoS 2 Nanosheets
Kenry, A Geldert, X Zhang, H Zhang, CT Lim |
ACS Sensors | 2016 |
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Artesunate-induced testicular injury: Oil from selected spices blend modulates redox homeostasis and exacerbates steroidogenesis in rat models
JA Ajiboye, OL Erukainure, EE Okoro, G Asieba |
Clinical Nutrition Experimental | 2016 |
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Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure–Activity Relationships
B Zhou, Y Wu, S Dalal, EF Merino, QF Liu, CH Xu, T Yuan, J Ding, DG Kingston, MB Cassera, JM Yue |
Journal of Natural Products | 2016 |
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Malaria in the Era of Food Fortification With Folic Acid
A Nzila, J Okombo, J Hyde |
Food and nutrition bulletin | 2016 |
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The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread
CJ Woodrow, NJ White, C Ooij |
FEMS Microbiology Reviews | 2016 |
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West Africa International Centers of Excellence for Malaria Research: Drug Resistance Patterns to Artemether–Lumefantrine in Senegal, Mali, and The Gambia
T Dieye, AD Ahouidi, D Nwakanma, M Affara, S Doumbia, B Dieye, A Abdullahi, A Ismaela, B Mbengue, M Ndiaye, J Shaffer, A Mbaye, A Diarra, L Sangare, JL Ndiaye, C Welty, M Coulibaly, AB Deme, SK Volkman, U D'Alessandro, M Diakite, DJ Krogstad, F Joof, R Daniels, DF Wirth, D Ndiaye, JF Gomis, O Koita, YD Ndiaye, AA Ngwa, N Sy |
The American journal of tropical medicine and hygiene | 2016 |
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Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria
S Chandrudu, M Skwarczynski, D Pattinson, SH Apte, DL Doolan, I Toth |
Biochemical Compounds | 2016 |
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Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure–Activity Relationships
B Zhou, Y Wu, S Dalal, EF Merino, QF Liu, CH Xu, T Yuan, J Ding, DG Kingston, MB Cassera, JM Yue |
Journal of Natural Products | 2016 |
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Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination Therapy
M Guerra, R Neres, P Salgueiro, C Mendes, N Ndong-Mabale, P Berzosa, B Sousa, AP Arez |
Antimicrobial agents and chemotherapy | 2016 |
|
In vitro sensitivity of Plasmodium falciparum clinical isolates to 4-aminoquinolines in Northeast Nigeria.
Balogun ST, Sandabe UK, Waziri IA, Jibrin J, Fehintola FA |
MalariaWorld journal | 2016 |
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Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker
KM Tun, M Imwong, KM Lwin, AA Win, TM Hlaing, T Hlaing, K Lin, MP Kyaw, K Plewes, MA Faiz, M Dhorda, PY Cheah, S Pukrittayakamee, EA Ashley, TJ Anderson, S Nair, M McDew-White, JA Flegg, EP Grist, P Guerin, RJ Maude, F Smithuis, AM Dondorp, NP Day, F Nosten, NJ White, CJ Woodrow |
The Lancet Infectious Diseases | 2015 |
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Fighting Malaria: Structure-Guided Discovery of Nonpeptidomimetic Plasmepsin Inhibitors
AP Huizing, M Mondal, AK Hirsch |
Journal of Medicinal Chemistry | 2015 |
|
Computational design and chemometric QSAR modeling of Plasmodium falciparum carbonic anhydrase inhibitors
S Singh |
Bioorganic & Medicinal Chemistry Letters | 2015 |
|
Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya
M Shah, Y Omosun, A Lal, C Odero, W Gatei, K Otieno, JE Gimnig, F Kuile, WA Hawley, B Nahlen, S Kariuki, E Walker, L Slutsker, M Hamel, YP Shi |
Malaria Journal | 2015 |
|
Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum
D Vullo, SD Prete, GM Fisher, KT Andrews, SA Poulsen, C Capasso, CT Supuran |
Bioorganic & Medicinal Chemistry | 2015 |
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Determinants of malaria diagnostic uptake in the retail sector: qualitative analysis from focus groups in Uganda
J Cohen, A Cox, W Dickens, K Maloney, F Lam, G Fink |
Malaria Journal | 2015 |
|
Cochrane Database of Systematic Reviews: Reviews
M Athuman, AM Kabanywanyi, AC Rohwer, M Athuman |
Cochrane Database of Systematic Reviews: Reviews | 2015 |
|
Cochrane Database of Systematic Reviews: Reviews
R Isba, B Zani, M Gathu, D Sinclair, D Sinclair |
Cochrane Database of Systematic Reviews: Reviews | 2015 |
|
Anti-malarial prescribing practices in Sudan eight years after introduction of artemisinin-based combination therapies and implications for development of drug resistance
AA Elmannan, KA Elmardi, YA Idris, JM Spector, NA Ali, EM Malik |
BMC Pharmacology and Toxicology | 2015 |
|
Anti-malarial activity and toxicity assessment of Himatanthus articulatus, a plant used to treat malaria in the Brazilian Amazon
VV Vale, TC Vilhena, RC Trindade, MR Ferreira, S Percário, LF Soares, WL Pereira, GC Brandão, AB Oliveira, MF Dolabela, FD Vasconcelos |
Malaria Journal | 2015 |
|
Comparing the Impact of Artemisinin-Based Combination Therapies on Malaria Transmission in Sub-Saharan Africa
ML Mbah, S Parikh, AP Galvani |
The American journal of tropical medicine and hygiene | 2015 |
|
Calibration of an intrahost malaria model and parameter ensemble evaluation of a pre-erythrocytic vaccine
KA McCarthy, EA Wenger, GH Huynh, PA Eckhoff |
Malaria Journal | 2015 |
|
Expression of active trypsin-like serine peptidases in the midgut of sugar-feeding female Anopheles aquasalis
G Dias-Lopes, A Borges-Veloso, L Saboia-Vahia, GB Domont, C Britto, P Cuervo, JB de Jesus |
Parasites & vectors | 2015 |
|
Tyrosine kinase inhibitors: New class of antimalarials on the horizon?
V Pathak, R Colah, K Ghosh |
Blood Cells, Molecules, and Diseases | 2015 |
|
Synthesis, antimalarial activity and molecular docking of hybrid 4-aminoquinoline-1,3,5-triazine derivatives
HR Bhat, UP Singh, A Thakur, SK Ghosh, K Gogoi, A Prakash, RK Singh |
Experimental Parasitology | 2015 |
|
Carbamoyl triazoles, Known Serine Protease Inhibitors, are a potent New Class of Antimalarial
P O´Neill, M McConville, J Fernandez-molina, I Angulo-Barturen, NR Bahamontes, L Ballell-Pages, PC Castaneda, CD De-Cozar, BF Crespo-Fernandez, LL Guijarro, BD Jimenez, J de-Mercado, A Santos-Villajero, L Sanz, G Washbourn, SA Ward, GL Nixon, GA Biagini, NG Berry, MJ Blackman, F Calderon |
Journal of Medicinal Chemistry | 2015 |
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Monitoring artemisinin resistance in Plasmodium falciparum: comparison of parasite clearance time by microscopy and real-time PCR and evaluation of mutations in Pfatpase6 gene in Odisha state of India
R Gupta, N Mishra, A Kumar, R Rana, B Srivastava, PK Tyagi, AR Anvikar, N Valecha |
Parasitology Research | 2015 |
|
In Silico Exploration for New Antimalarials: Arylsulfonyloxy Acetimidamides as Prospective Agents
S Verma, U Debnath, P Agarwal, K Srivastava, YS Prabhakar |
Journal of Chemical Information and Modeling | 2015 |
|
Seasonality in malaria transmission: implications for case-management with long-acting artemisinin combination therapy in sub-Saharan Africa
ME Cairns, PG Walker, LC Okell, JT Griffin, T Garske, KP Asante, S Owusu-Agyei, D Diallo, A Dicko, B Cisse, BM Greenwood, D Chandramohan, AC Ghani, PJ Milligan |
Malaria Journal | 2015 |
|
Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions
CJ Woodrow, C Wangsing, K Sriprawat, PR Christensen, F Nosten, L Rénia, B Russell, B Malleret, PH Gilligan |
Journal of clinical microbiology | 2015 |
|
Introducing rapid diagnostic tests for malaria to drug shops in Uganda: a cluster-randomized controlled trial
J Cohen, G Fink, K Maloney, K Berg, M Jordan, T Svoronos, F Aber, W Dickens |
Bulletin of the World Health Organization | 2015 |
|
Synthesis, chemical structure elucidation, and biological studies on the effect of some vital metal ions on sulfadoxine
M Zaky, MY El-Sayed, SM El-Megharbel, SA Taleb, MS Refat |
Russian Journal of General Chemistry | 2015 |
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Price Subsidies, Diagnostic Tests, and Targeting of Malaria Treatment: Evidence from a Randomized Controlled Trial †
J Cohen, P Dupas, S Schaner |
The American Economic Review | 2015 |
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Global analysis of a mathematical model on malaria with competitive strains and immune responses
H Chen, W Wang, R Fu, J Luo |
Applied Mathematics and Computation | 2015 |
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Efficacy in the treatment of malaria by Plasmodium vivax in Oiapoque, Brazil, on the border with French Guiana: the importance of control over external factors
MS Gomes, JL Vieira, RL Machado, M Nacher, A Stefani, L Musset, E Legrand, RA Menezes, AA Júnior, AP Sousa, VS Couto, ÁA Couto |
Malaria Journal | 2015 |
|
Bioeconomic analysis of child-targeted subsidies for artemisinin combination therapies: a cost-effectiveness analysis
Eili Y Klein, David L Smith, Justin M Cohen, Ramanan Laxminarayan |
Journal of The Royal Society Interface | 2015 |
|
Identification of novel class of falcipain-2 inhibitors as potential antimalarial agents
SK Chakka, M Kalamuddin, S Sundararaman, L Wei, S Mundra, R Mahesh, P Malhotra, A Mohmmed, LP Kotra |
Bioorganic & Medicinal Chemistry | 2015 |
|
New paradigm of an old target: An update on structural biology and current progress in drug design towards plasmepsin II
N Dan, S Bhakat |
European Journal of Medicinal Chemistry | 2015 |
|
A systematic review of the efficacy of a single dose artemisinin–naphthoquine in treating uncomplicated malaria
C Naing, MA Whittaker, JW Mak, K Aung |
Malaria Journal | 2015 |
|
How genomics is contributing to the fight against artemisinin-resistant malaria parasites
P Cravo, H Napolitano, R Culleton |
Acta Tropica | 2015 |
|
Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites
NA Pereira, Â Monteiro, M Machado, J Gut, E Molins, MJ Perry, J Dourado, R Moreira, PJ Rosenthal, M Prudêncio, MM Santos |
ChemMedChem | 2015 |
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Rapid diagnostic tests for malaria
T Visser, J Daily, N Hotte, C Dolkart, J Cunningham, P Yadav |
Bulletin of the World Health Organization | 2015 |
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Possible Synergistic Effects of Thymol and Nicotine against Crithidia bombi Parasitism in Bumble Bees
OM Biller, LS Adler, RE Irwin, C McAllister, EC Palmer-Young, C Rodriguez-Saona |
PloS one | 2015 |
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Attrition in the Pharmaceutical Industry: Reasons, Implications, and Pathways Forward
PM Njogu, K Chibale |
Attrition in the Pharmaceutical Industry: Reasons, Implications, and Pathways Forward | 2015 |
|
On the molecular basis of the activity of the antimalarial drug chloroquine: EXAFS-assisted DFT evidence of a direct Fe–N bond with free heme in solution
G Macetti, S Rizzato, F Beghi, L Silvestrini, LL Presti |
Physica Scripta | 2015 |
|
Do It Well or Not at All? Malaria Control and Child Development in Zambia
GG Fink, A Venkataramani, A Zanolini |
SSRN Electronic Journal | 2015 |
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Fluorine modulates species selectivity in the triazolopyrimidine class of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors
X Deng, S Kokkonda, FE Mazouni, J White, JN Burrows, W Kaminsky, SA Charman, D Matthews, PK Rathod, MA Phillips |
Journal of Medicinal Chemistry | 2014 |
|
The impact of heterogeneous transmission on the establishment and spread of antimalarial drug resistance
EY Klein |
Journal of Theoretical Biology | 2014 |
|
Influence of formulation ratio of the plant components on the antimalarial properties of MAMA decoction
SA Odediran, AA Elujoba, AC Adebajo |
Parasitology Research | 2014 |
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Cochrane Database of Systematic Reviews: Reviews
H Bukirwa, B Unnikrishnan, CV Kramer, D Sinclair, S Nair, P Tharyan, H Bukirwa |
Cochrane Database of Systematic Reviews: Reviews | 2014 |
|
The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids
F Ntie-Kang, P Onguéné, LL Lifongo, J Ndom, W Sippl, L Mbaze |
Malaria Journal | 2014 |
|
Rapid response to selection, competitive release and increased transmission potential of artesunate-selected Plasmodium chabaudi malaria parasites
LC Pollitt, S Huijben, DG Sim, RM Salathé, MJ Jones, AF Read |
PLoS pathogens | 2014 |
|
Cross-talk between malarial cysteine proteases and falstatin: the BC loop as a hot-spot target
S Sundararaj, AK Saxena, R Sharma, K Vashisht, S Sharma, A Anvikar, R Dixit, PJ Rosenthal, KC Pandey |
PloS one | 2014 |
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The potential of anti-malarial compounds derived from African medicinal plants, part III: an in silico evaluation of drug metabolism and pharmacokinetics profiling
PA Onguéné, F Ntie-Kang, JA Mbah, LL Lifongo, JC Ndom, W Sippl, LM Mbaze |
Organic and Medicinal Chemistry Letters | 2014 |
|
Chemical Interrogation of the Malaria Kinome
ER Derbyshire, V Zuzarte-Luís, AD Magalhães, N Kato, PC Sanschagrin, J Wang, W Zhou, CV Miduturu, R Mazitschek, P Sliz, MM Mota, NS Gray, J Clardy |
ChemBioChem | 2014 |
|
Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring
LC Pollitt, D Sim, R Salathé, AF Read |
Evolutionary Applications | 2014 |
|
A retrospective evaluation of the quality of malaria case management at twelve health facilities in four districts in Zambia
P Chanda-Kapata, E Chanda, F Masaninga, A Habluetzel, F Masiye, IS Fall |
Asian Pacific Journal of Tropical Biomedicine | 2014 |
|
A review of the effects of artemether-lumefantrine on gametocyte carriage and disease transmission
M Makanga |
Malaria Journal | 2014 |
|
A population genetic model for the initial spread of partially resistant malaria parasites under anti-malarial combination therapy and weak intrahost competition
Y Kim, AA Escalante, KA Schneider |
PloS one | 2014 |
|
“We have become doctors for ourselves”: motives for malaria self-care among adults in southeastern Tanzania
E Metta, H Haisma, F Kessy, I Hutter, A Bailey |
Malaria Journal | 2014 |
|
The effect of the Pheroid delivery system on the in vitro metabolism and in vivo pharmacokinetics of artemisone
L Grobler, A Grobler, R Haynes, C Masimirembwa, R Thelingwani, P Steenkamp, HS Steyn |
Expert Opinion on Drug Metabolism & Toxicology | 2014 |
|
In silico investigation of medicinal spectrum of imidazo-azines from the perspective of multitarget screening against malaria, tuberculosis and Chagas disease
M Kumar, B Makhal, VK Gupta, A Sharma |
Journal of Molecular Graphics and Modelling | 2014 |
|
Design and Synthesis of a New Class of 4-Aminoquinolinyl- and 9-Anilinoacridinyl Schiff Base Hydrazones as Potent Antimalarial Agents
M Sharma, K Chauhan, RK Srivastava, SV Singh, K Srivastava, JK Saxena, SK Puri, PM Chauhan |
Chemical Biology & Drug Design | 2014 |
|
A unique insertion of low complexity amino acid sequence underlies protein-protein interaction in human malaria parasite orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase
W Imprasittichail, S Roytrakul, SR Krungkrai, J Krungkrail |
Asian Pacific Journal of Tropical Medicine | 2014 |
|
Evaluation of the Ex vivo Antimalarial Activity of Organotin (IV) Ethylphenyldithiocarbamate on Erythrocytes Infected With Plasmodium berghei Nk 65
N Awang, H Jumat, SA Ishak, NF Kamaludin |
Pakistan Journal of Biological Sciences | 2014 |
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The path of least resistance: aggressive or moderate treatment?
RD Kouyos, CJ Metcalf, R Birger, EY Klein, PA Wiesch, P Ankomah, N Arinaminpathy, TL Bogich, S Bonhoeffer, C Brower, G Chi-Johnston, T Cohen, T Day, B Greenhouse, S Huijben, J Metlay, N Mideo, LC Pollitt, AF Read, DL Smith, C Standley, N Wale, B Grenfell |
Proceedings of the Royal Society B: Biological Sciences | 2014 |
|
Antiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea angustifolia in Plasmodium berghei infected mice
W Amelo, P Nagpal, E Makonnen |
BMC complementary and alternative medicine | 2014 |
|
Malaria Vaccines: Progressing on a Bumpy Road
G Corradin, I Nebie |
EBioMedicine | 2014 |
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In vitro and in silico antimalarial activity of 2-(2-hydrazinyl)thiazole derivatives
P Makam, PK Thakur, T Kannan |
European Journal of Pharmaceutical Sciences | 2014 |
|
Mutations in Plasmodium falciparum K13 propeller gene from Bangladesh (2009–2013)
A Mohon, M Alam, A Bayih, A Folefoc, D Shahinas, R Haque, DR Pillai |
Malaria Journal | 2014 |
|
Synthesis and Antimalarial Activities of Some Novel 2-Pyridones
SA Nethavhani, T Ree |
Arabian Journal for Science and Engineering | 2014 |
|
1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics evaluation
JN Hanna, F Ntie-Kang, M Kaiser, R Brun, SM Efange |
RSC Advances | 2014 |
|
Pharmacokinetic-Pharmacodynamic Analysis of Spiroindolone Analogs and KAE609 in a Murine Malaria Model
SB Lakshminarayana, C Freymond, C Fischli, J Yu, S Weber, A Goh, BK Yeung, PC Ho, V Dartois, TT Diagana, M Rottmann, F Blasco |
Antimicrobial agents and chemotherapy | 2014 |
|
Low-cost, High-speed identification of counterfeit antimalarial Drugs on paper
MT Koesdjojo, Y Wu, A Boonloed, EM Dunfield, VT Remcho |
Talanta | 2014 |
|
Perceptions of malaria and acceptance of rapid diagnostic tests and related treatment practises among community members and health care providers in Greater Garissa, North Eastern Province, Kenya
E Diggle, R Asgary, G Gore-Langton, E Nahashon, J Mungai, R Harrison, A Abagira, K Eves, Z Grigoryan, D Soti, E Juma, R Allan |
Malaria Journal | 2014 |
|
The Origins of Antimalarial-Drug Resistance
RM Packard |
New England Journal of Medicine | 2014 |
|
A Population Genetic Model for the Initial Spread of Partially Resistant Malaria Parasites under Anti-Malarial Combination Therapy and Weak Intrahost Competition
Y Kim, AA Escalante, KA Schneider, DJ Sullivan |
PloS one | 2014 |
|
In Vivo Antiplasmodial Potentials of the Combinations of Four Nigerian Antimalarial Plants
A Adebajo, S Odediran, F Aliyu, P Nwafor, N Nwoko, U Umana |
Molecules (Basel, Switzerland) | 2014 |
|
Cross-Talk between Malarial Cysteine Proteases and Falstatin: The BC Loop as a Hot-Spot Target
S Sundararaj, AK Saxena, R Sharma, K Vashisht, S Sharma, A Anvikar, R Dixit, PJ Rosenthal, KC Pandey, M Bogyo |
PloS one | 2014 |
|
Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites
LC Pollitt, S Huijben, DG Sim, RM Salathé, MJ Jones, AF Read, TJ Anderson |
PLoS pathogens | 2014 |
|
Plasmodium berghei ANKA: Selection of pyronaridine resistance in mouse model
SK Kimani, JK Nganga, DW Kariuki, J Kinyua, FT Kimani, DM Kiboi |
African Journal of Biochemistry Research | 2014 |
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Design, Synthesis, and Antiplasmodial Activity of Hybrid Compounds Based on (2 R ,3 S )- N -Benzoyl-3-phenylisoserine
PM Njogu, J Gut, PJ Rosenthal, K Chibale |
ACS Medicinal Chemistry Letters | 2013 |
|
Novel anti-Plasmodial hits identified by virtual screening of the ZINC database
G Mugumbate, AS Newton, PJ Rosenthal, J Gut, R Moreira, K Chibale, RC Guedes |
Journal of Computer-Aided Molecular Design | 2013 |
|
Genetics of chloroquine-resistant malaria: a haplotypic view
G Awasthi, A Das |
Memórias do Instituto Oswaldo Cruz | 2013 |
|
Pharmacokinetic and pharmacodynamic considerations in antimalarial dose optimization
NJ White |
Antimicrobial agents and chemotherapy | 2013 |
|
Discovery of new potential hits of Plasmodium falciparum enoyl-ACP reductase through ligand- and structure-based drug design approaches
BJ Neves, RV Bueno, RC Braga, CH Andrade |
Bioorganic & Medicinal Chemistry Letters | 2013 |
|
Eradication of malaria through genetic engineering: the current situation
WC Chong, R Basir, YM Fei |
Asian Pacific Journal of Tropical Medicine | 2013 |
|
Progress in the Understanding of the Key Pharmacophoric Features of the Antimalarial Drug Dihydroartemisinin: An Experimental and Theoretical Charge Density Study
G Saleh, R Soave, L Lo Presti, R Destro |
Chemistry - A European Journal | 2013 |
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eLS
YC Chang, YH Yu, LM Chuang |
Encyclopedia of Life Sciences | 2013 |
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Amodiaquine-Artesunate versus Artemether-Lumefantrine against Uncomplicated Malaria in Children Less Than 14 Years in Ngaoundere, North Cameroon: Efficacy, Safety, and Baseline Drug Resistant Mutations in pfcrt, pfmdr1, and pfdhfr Genes
IM Ali, PM Netongo, B Atogho-Tiedeu, EO Ngongang, A Ajua, EA Achidi, WF Mbacham |
Malaria Research and Treatment | 2013 |
|
Injections, cocktails and diviners: therapeutic flexibility in the context of malaria elimination and drug resistance in Northeast Cambodia
C Gryseels, S Uk, A Erhart, R Gerrets, V Sluydts, L Durnez, JM Ribera, SH Muela, D Menard, S Heng, T Sochantha, U D'Alessandro, M Coosemans, KP Grietens |
PloS one | 2013 |
|
Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate
H Matthews, M Usman-Idris, F Khan, M Read, N Nirmalan |
Malaria Journal | 2013 |
|
Phytochemical Analysis and Antimalarial Activity Aqueous Extract of Lecaniodiscus cupanioides Root
MO Nafiu, TA Abdulsalam, MA Akanji |
Journal of Tropical Medicine | 2013 |
|
Malaria prevalence, spatial clustering and risk factors in a low endemic area of Eastern Rwanda: a cross sectional study
S Rulisa, F Kateera, JP Bizimana, S Agaba, J Dukuzumuremyi, L Baas, JD Harelimana, PF Mens, KR Boer, PJ de Vries |
PloS one | 2013 |
|
Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan
NB Gadalla, TM Abdallah, S Atwal, CJ Sutherland, I Adam |
Malaria Journal | 2013 |
|
A randomized trial of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated malaria among children in western Kenya
A Agarwal, M McMorrow, P Onyango, K Otieno, C Odero, J Williamson, S Kariuki, SP Kachur, L Slutsker, M Desai |
Malaria Journal | 2013 |
|
Malariometric survey of ibeshe community in ikorodu, lagos state: dry season
OO Aina, CO Agomo, YA Olukosi, HI Okoh, BA Iwalokun, KN Egbuna, AB Orok, O Ajibaye, VN Enya, SK Akindele, MO Akinyele, PU Agomo |
Malaria Research and Treatment | 2013 |
|
Over-diagnosis of malaria by microscopy in the Kilombero Valley, Southern Tanzania: an evaluation of the utility and cost-effectiveness of rapid diagnostic tests
K Harchut, C Standley, A Dobson, B Klaassen, C Rambaud-Althaus, F Althaus, K Nowak |
Malaria Journal | 2013 |
|
A novel flow cytometric hemozoin detection assay for real-time sensitivity testing of Plasmodium falciparum
M Rebelo, C Sousa, HM Shapiro, MM Mota, MP Grobusch, T Hänscheid |
PloS one | 2013 |
|
Prevalence of antifolate resistance mutations in Plasmodium falciparum isolates in Afghanistan
GR Awab, S Pukrittayakamee, N Jamornthanyawat, F Yamin, AM Dondorp, NP Day, NJ White, CJ Woodrow, M Imwong |
Malaria Journal | 2013 |
|
A SAR and QSAR Study of New Artemisinin Compounds with Antimalarial Activity
C Santos, J Vieira, C Lobato, L Hage-Melim, R Souto, C Lima, E Costa, D Brasil, W Macêdo, J Carvalho |
Molecules (Basel, Switzerland) | 2013 |
|
Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasites
ER Derbyshire, J Min, WA Guiguemde, JA Clark, MC Connelly, AD Magalhães, RK Guy, J Clardy |
Antimicrobial agents and chemotherapy | 2013 |
|
Induction of an Antibody Response against Plasmodium falciparum F2RIIEBA by Heterologous Prime-boost Immunisation
R Suppian, NM Nor |
2013 | |
|
Novel Selective and Potent Inhibitors of Malaria Parasite Dihydroorotate Dehydrogenase: Discovery and Optimization of Dihydrothiophenone Derivatives
M Xu, J Zhu, Y Diao, H Zhou, X Ren, D Sun, J Huang, D Han, Z Zhao, L Zhu, Y Xu, H Li |
Journal of Medicinal Chemistry | 2013 |
|
Artemether and lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa
B Ogutu |
Expert Opinion on Pharmacotherapy | 2013 |
|
Antimalarial drug resistance: a review of the biology and strategies to delay emergence and spread
EY Klein |
International Journal of Antimicrobial Agents | 2013 |
|
Artemisinin resistance in Plasmodium falciparum: what is it really?
PE Ferreira, R Culleton, JP Gil, SR Meshnick |
Trends in Parasitology | 2013 |
|
Isolation and identification of β-hematin inhibitors from Flacourtia indica as promising antiplasmodial agents
KV Sashidhara, SP Singh, SV Singh, RK Srivastava, K Srivastava, JK Saxena, SK Puri |
European Journal of Medicinal Chemistry | 2013 |
|
The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine–guanine–(xanthine) phosphoribosyltransferases
O Baszczyňski, D Hocková, Z Janeba, A Holý, P Jansa, M Dračínský, DT Keough, LW Guddat |
European Journal of Medicinal Chemistry | 2013 |
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PfHPRT: A New Biomarker Candidate of Acute Plasmodium falciparum Infection
ML Thézénas, H Huang, M Njie, A Ramaprasad, DC Nwakanma, R Fischer, K Digleria, M Walther, DJ Conway, BM Kessler, C Casals-Pascual |
Journal of Proteome Research | 2013 |
|
Methylerythritol phosphate pathway to isoprenoids: Kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum
VK Singh, I Ghosh |
FEBS Letters | 2013 |
|
Sulfadoxine-pyrimethamine resistance in Plasmodium falciparum: A zoomed image at the molecular level within a geographic context
R Abdul-Ghani, HF Farag, AF Allam |
Acta Tropica | 2013 |
|
Plasmodium Drug Targets Outside the Genetic Control of the Parasite
David J. Sullivan Jr. |
Current pharmaceutical design | 2013 |
|
DEVELOPMENT OF A FORCE FIELD FOR ARTEMISININ AND MOLECULAR DYNAMICS SIMULATION OF THE DISSOLUTION OF ARTEMISININ IN DIFFERENT SOLVENTS
Q Yang, LE Achenie |
Journal of Theoretical and Computational Chemistry | 2013 |
|
Changing the malaria treatment protocol policy in Timor-Leste: an examination of context, process, and actors’ involvement
JS Martins, AB Zwi, K Hobday, F Bonaparte, PM Kelly |
Health Research Policy and Systems | 2013 |
|
Malaria Prevalence, Spatial Clustering and Risk Factors in a Low Endemic Area of Eastern Rwanda: A Cross Sectional Study
S Rulisa, F Kateera, JP Bizimana, S Agaba, J Dukuzumuremyi, L Baas, JD Harelimana, PF Mens, KR Boer, PJ de Vries, AM Noor |
PloS one | 2013 |
|
Injections, Cocktails and Diviners: Therapeutic Flexibility in the Context of Malaria Elimination and Drug Resistance in Northeast Cambodia
C Gryseels, S Uk, A Erhart, R Gerrets, V Sluydts, L Durnez, JM Ribera, SH Muela, D Menard, S Heng, T Sochantha, U DAlessandro, M Coosemans, KP Grietens, LH Carvalho |
PloS one | 2013 |
|
A Novel Flow Cytometric Hemozoin Detection Assay for Real-Time Sensitivity Testing of Plasmodium falciparum
M Rebelo, C Sousa, HM Shapiro, MM Mota, MP Grobusch, T Hänscheid, S Borrmann |
PloS one | 2013 |
|
Genetics of chloroquine-resistant malaria: a haplotypic view
G Awasthi, A Das |
Memórias do Instituto Oswaldo Cruz | 2013 |
|
Comparison of bioavailability between the most available generic tablet formulation containing artemether and lumefantrine on the Tanzanian market and the innovator’s product
OM Minzi, IA Marealle, S Shekalaghe, O Juma, E Ngaimisi, M Chemba, M Rutaihwa, S Abdulla, P Sasi |
Malaria Journal | 2013 |
|
Heat Shock Proteins of Malaria
A Shonhai, GL Blatch |
2013 | |
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Treatment of Human Parasitosis in Traditional Chinese Medicine
H Mehlhorn, Z Wu, B Ye |
2013 | |
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Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants
M Shahid, A Shahzad, A Malik, A Sahai |
2013 | |
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The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids
PA Onguéné, F Ntie-Kang, LL Lifongo, JC Ndom, W Sippl, LM Mbaze |
Malaria Journal | 2013 |
|
Bioisosteric Transformations and Permutations in the Triazolopyrimidine Scaffold To Identify the Minimum Pharmacophore Required for Inhibitory Activity against Plasmodium falciparum Dihydroorotate Dehydrogenase
A Marwaha, J White, F El_Mazouni, SA Creason, S Kokkonda, FS Buckner, SA Charman, MA Phillips, PK Rathod |
Journal of Medicinal Chemistry | 2012 |
|
Superinfection and the evolution of resistance to antimalarial drugs
EY Klein, DL Smith, R Laxminarayan, S Levin |
Proceedings of the Royal Society B: Biological Sciences | 2012 |
|
The effects of serum lipids on the in vitro activity of lumefantrine and atovaquone against Plasmodium falciparum
K Chotivanich, M Mungthin, R Ruengweerayuth, R Udomsangpetch, AM Dondorp, P Singhasivanon, S Pukrittayakamee, NJ White |
Malaria Journal | 2012 |
|
Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-κB Pathway in Microglia Cells
C Zhu, Z Xiong, X Chen, F Peng, X Hu, Y Chen, Q Wang |
PloS one | 2012 |
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No Evidence for Spread of Plasmodium falciparum Artemisinin Resistance to Savannakhet Province, Southern Laos
M Mayxay, M Khanthavong, O Chanthongthip, M Imwong, SJ Lee, K Stepniewska, B Soonthornsata, T Pongvongsa, S Phompida, B Hongvanthong, P Ringwald, NJ White, PN Newton |
The American journal of tropical medicine and hygiene | 2012 |
|
Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods
R Sharma, AS Lawrenson, NE Fisher, AJ Warman, AE Shone, A Hill, A Mbekeani, C Pidathala, RK Amewu, S Leung, P Gibbons, DW Hong, P Stocks, GL Nixon, J Chadwick, J Shearer, I Gowers, D Cronk, SP Parel, PM O'Neill, SA Ward, GA Biagini, NG Berry |
Journal of Medicinal Chemistry | 2012 |
|
Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)
C Pidathala, R Amewu, B Pacorel, GL Nixon, P Gibbons, WD Hong, SC Leung, NG Berry, R Sharma, PA Stocks, A Srivastava, AE Shone, S Charoensutthivarakul, L Taylor, O Berger, A Mbekeani, A Hill, NE Fisher, AJ Warman, GA Biagini, SA Ward, PM O'Neill |
Journal of Medicinal Chemistry | 2012 |
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Primacy of effective communication and its influence on adherence to artemether-lumefantrine treatment for children under five years of age: a qualitative study
DO Simba, D Kakoko |
BMC health services research | 2012 |
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The in silico screening and X-ray structure analysis of the inhibitor complex of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase
Y Takashima, E Mizohata, SR Krungkrai, Y Fukunishi, T Kinoshita, T Sakata, H Matsumura, J Krungkrai, T Horii, T Inoue |
Journal of Biochemistry | 2012 |
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Drug discovery and development: lessons from an undeveloped drug
T Gordi |
Expert Review of Clinical Pharmacology | 2012 |
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Autoinduction of phase I and phase II metabolism of artemisinin in rats
J Xing, FY Du, T Liu, FP Zhu |
Xenobiotica | 2012 |
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The Alkaloids: Chemistry and Biology
GW Gribble |
The Alkaloids: Chemistry and Biology | 2012 |
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3D QSAR studies on 5-(2-methylbenzimidazol-1-yl)-N-alkylthiophene-2-carboxamide derivatives as P. falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors
VK Vyas, H Parikh, M Ghate |
Medicinal Chemistry Research | 2012 |
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Lead Hopping for PfDHODH Inhibitors as Antimalarials Based on Pharmacophore Mapping, Molecular Docking and Comparative Binding Energy Analysis (COMBINE): A Three-Layered Virtual Screening Approach
P Kumar Ojha, I Mitra, S Kar, R Narayan Das, K Roy |
Molecular Informatics | 2012 |
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In silico identification of novel inhibitors against Plasmodium falciparum dihydroorate dehydrogenase
A Wadood, Z -Haq |
Journal of Molecular Graphics and Modelling | 2012 |
|
Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance
T Mita, K Tanabe |
Japanese Journal of Infectious Diseases | 2012 |
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Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cells
EF Oga, S Sekine, Y Shitara, T Horie |
The American journal of tropical medicine and hygiene | 2012 |
|
Chemotherapeutics challenges in developing effective treatments for the endemic malarias
JK Baird |
International Journal for Parasitology Drugs and Drug Resistance | 2012 |
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Monitoring antimalarial drug resistance: Applying lessons learned from the past in a fast-moving present
CH Sibley, RN Price |
International Journal for Parasitology Drugs and Drug Resistance | 2012 |
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Feasibility of distributing rapid diagnostic tests for malaria in the retail sector: evidence from an implementation study in Uganda
J Cohen, G Fink, K Berg, F Aber, M Jordan, K Maloney, W Dickens |
PloS one | 2012 |
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Dual fluorescent labelling of the human malaria parasite Plasmodium falciparum for the analysis of the ABC type transporter pfmdr2
B Rosental, U Hadad, R Sinay, A Braiman, A Porgador, Y Pollack |
Malaria Journal | 2012 |
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Artemisinin resistance containment project in Thailand. II: Responses to mefloquine-artesunate combination therapy among falciparum malaria patients in provinces bordering Cambodia
W Satimai, P Sudathip, S Vijaykadga, A Khamsiriwatchara, S Sawang, T Potithavoranan, A Sangvichean, C Delacollette, P Singhasivanon, J Kaewkungwal, S Lawpoolsri |
Malaria Journal | 2012 |
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Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania
DT Minja, C Schmiegelow, M Oesterholt, PA Magistrado, S Boström, D John, C Pehrson, D Andersen, P Deloron, A Salanti, M Lemnge, AJ Luty, M Alifrangis, T Theander, JP Lusingu |
Malaria Journal | 2012 |
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Compliance, safety, and effectiveness of fixed-dose artesunate-amodiaquine for presumptive treatment of non-severe malaria in the context of home management of malaria in Madagascar
A Ratsimbasoa, H Ravony, JA Vonimpaisomihanta, R Raherinjafy, M Jahevitra, R Rapelanoro, JD Rakotomanga, D Malvy, P Millet, D Ménard |
The American journal of tropical medicine and hygiene | 2012 |
|
The Effect of Otostegia persica in Combination with Chloroquine on Chloroquine-Sensitive and Chloroquine-Resistant Strains of Plasmodium berghei Using In-vivo Fixed Ratios Method
M Nateghpour, L Farivar, E Souri, H Hajjaran, M Mohebali, AM Haghi |
IRAN J PHARM RES | 2012 |
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Outwitting Evolution: Fighting Drug-Resistant TB, Malaria, and HIV
DE Goldberg, RF Siliciano, WR Jacobs |
Cell | 2012 |
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Adherence to artemether/lumefantrine treatment in children under real-life situations in rural Tanzania
DO Simba, D Kakoko, G Tomson, Z Premji, M Petzold, M Mahindi, LL Gustafsson |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2012 |
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Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects: ARS and DHA pharmacokinetics in pregnancy
R McGready, AP Phyo, MJ Rijken, J Tarning, N Lindegardh, W Hanpithakpon, HH Than, N Hlaing, NT Zin, P Singhasivanon, NJ White, F Nosten |
British Journal of Clinical Pharmacology | 2012 |
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Malaria in the Greater Mekong Subregion: Heterogeneity and complexity
L Cui, G Yan, J Sattabongkot, Y Cao, B Chen, X Chen, Q Fan, Q Fang, S Jongwutiwes, D Parker, J Sirichaisinthop, MP Kyaw, X Su, H Yang, Z Yang, B Wang, J Xu, B Zheng, D Zhong, G Zhou |
Acta Tropica | 2012 |
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Qualitative-(semi)quantitative data acquisition of artemisinin and its metabolites in rat plasma using an LTQ/Orbitrap mass spectrometer: Qualitative-quantitative data acquisition of QHS
F Du, T Liu, T Shen, F Zhu, J Xing |
Journal of Mass Spectrometry | 2012 |
|
Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)
SC Leung, P Gibbons, R Amewu, GL Nixon, C Pidathala, WD Hong, B Pacorel, NG Berry, R Sharma, PA Stocks, A Srivastava, AE Shone, S Charoensutthivarakul, L Taylor, O Berger, A Mbekeani, A Hill, NE Fisher, AJ Warman, GA Biagini, SA Ward, PM O’Neill |
Journal of Medicinal Chemistry | 2012 |
|
Aryl aryl methyl thio arenes prevent multidrug-resistant malaria in mouse by promoting oxidative stress in parasites
M Goyal, P Singh, A Alam, SK Das, MS Iqbal, S Dey, S Bindu, C Pal, SK Das, G Panda, U Bandyopadhyay |
Free radical biology & medicine | 2012 |
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Antimalarial and anticancer activities of artemisinin–quinoline hybrid-dimers and pharmacokinetic properties in mice
MC Lombard, DD N’Da, JC Breytenbach, NI Kolesnikova, CT van Ba, S Wein, J Norman, P Denti, H Vial, L Wiesner |
European Journal of Pharmaceutical Sciences | 2012 |
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Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms: Antimalarial drugs and CAR
O Burk, R Piedade, L Ghebreghiorghis, JT Fait, AK Nussler, JP Gil, B Windshügel, M Schwab |
British Journal of Pharmacology | 2012 |
|
Malaria Parasites, Traditional Medicinal Plants and Artediffusin (Tehranolide) as a New Candidate of Antimalaria Agent
A Rustaiyan, M vahedi |
Journal of Biologically Active Products from Nature | 2012 |
|
Plasmodium drug targets outside the genetic control of the parasite
David J Sullivan |
Current pharmaceutical design | 2012 |
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Synthesis of 2-ferrocenylquinoline derivatives and evaluation of their antimalarial activity
A Patti, S Pedotti, T Grassi, A Idolo, M Guido, AD Donno |
Journal of Organometallic Chemistry | 2012 |
|
COMPUTATIONAL MODELING OF ANTIMALARIAL 10-SUBSTITUTED DEOXOARTEMISININS
MD Cristino, CC de Meneses, MM Soeiro, JE Ferreira, AF de Figueiredo, JP Barbosa, RC de Almeida, JC Pinheiro, AD Pinheiro |
Journal of Theoretical and Computational Chemistry | 2012 |
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Erythrocyte membranes convert monomeric ferriprotoporphyrin IX to β -hematin in acidic environment at malarial fever temperature
AU Orjih, TC Mathew, PT Cherian |
Experimental biology and medicine (Maywood, N.J.) | 2012 |
|
Feasibility of Distributing Rapid Diagnostic Tests for Malaria in the Retail Sector: Evidence from an Implementation Study in Uganda
J Cohen, G Fink, K Berg, F Aber, M Jordan, K Maloney, W Dickens, C Shiff |
PloS one | 2012 |
|
Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-κB Pathway in Microglia Cells
C Zhu, Z Xiong, X Chen, F Peng, X Hu, Y Chen, Q Wang, ML Block |
PloS one | 2012 |
|
No Evidence for Spread of Plasmodium falciparum Artemisinin Resistance to Savannakhet Province, Southern Laos
O Chanthongthip, NJ White, T Pongvongsa, M Mayxay, M Imwong, B Hongvanthong, K Stepniewska, PN Newton, S Phompida, SJ Lee, M Khanthavong, P Ringwald, B Soonthornsata |
The American journal of tropical medicine and hygiene | 2012 |
|
Compliance, Safety, and Effectiveness of Fixed-Dose Artesunate-Amodiaquine for Presumptive Treatment of Non-Severe Malaria in the Context of Home Management of Malaria in Madagascar
D Malvy, D Ménard, R Rapelanoro, R Raherinjafy, P Millet, A Ratsimbasoa, H Ravony, JD Rakotomanga, M Jahevitra, JA Vonimpaisomihanta |
The American journal of tropical medicine and hygiene | 2012 |
|
Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)
C Pidathala, R Amewu, B Pacorel, GL Nixon, P Gibbons, WD Hong, SC Leung, NG Berry, R Sharma, PA Stocks, A Srivastava, AE Shone, S Charoensutthivarakul, L Taylor, O Berger, A Mbekeani, A Hill, NE Fisher, AJ Warman, GA Biagini, SA Ward, PM ONeill |
Journal of Medicinal Chemistry | 2012 |
|
Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: Increasing Hit Rate via Virtual Screening Methods
R Sharma, AS Lawrenson, NE Fisher, AJ Warman, AE Shone, A Hill, A Mbekeani, C Pidathala, RK Amewu, S Leung, P Gibbons, DW Hong, P Stocks, GL Nixon, J Chadwick, J Shearer, I Gowers, D Cronk, SP Parel, PM O'Neill, SA Ward, GA Biagini, NG Berry |
Journal of Medicinal Chemistry | 2012 |
|
Recent advances and perspectives on tropical diseases: Malaria
N Micale |
World Journal of Translational Medicine | 2012 |
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Evaluation of P450 Inhibition and Induction by Artemisinin Antimalarials in Human Liver Microsomes and Primary Human Hepatocytes
J Xing, BJ Kirby, D Whittington, Y Wan, DR Goodlett |
Drug Metabolism and Disposition | 2012 |
|
Drug Discovery in Africa
K Chibale, M Davies-Coleman, C Masimirembwa |
2012 | |
|
Pharmacological Potential of Selected Natural Compounds in the Control of Parasitic Diseases
G Hrckova, S Velebny |
2012 | |
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The global pipeline of new medicines for the control and elimination of malaria
MP Anthony, JN Burrows, S Duparc, J JMoehrle, TN Wells |
Malaria Journal | 2012 |
|
Crystallization and preliminary X-ray diffraction analysis of orotate phosphoribosyltransferase from the human malaria parasite Plasmodium falciparum
Y Takashima, E Mizohata, K Tokuoka, SR Krungkrai, Y Kusakari, S Konishi, A Satoh, H Matsumura, J Krungkrai, T Horii, T Inoue |
Acta Crystallographica Section F Structural Biology and Crystallization Communications | 2012 |
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Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential
JM Coteron, M Marco, J Esquivias, X Deng, KL White, J White, M Koltun, FE Mazouni, S Kokkonda, K Katneni, R Bhamidipati, DM Shackleford, I Angulo-Barturen, SB Ferrer, MB Jiménez-Díaz, FJ Gamo, EJ Goldsmith, WN Charman, I Bathurst, D Floyd, D Matthews, JN Burrows, PK Rathod, SA Charman, MA Phillips |
Journal of Medicinal Chemistry | 2011 |
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Lead-optimization of aryl and aralkyl amine based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice
R Gujjar, FE Mazouni, KL White, J White, S Creason, DM Shackleford, X Deng, WN Charman, I Bathurst, J Burrows, DM Floyd, D Matthews, FS Buckner, SA Charman, MA Phillips, PK Rathod |
Journal of Medicinal Chemistry | 2011 |
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Bioinorganic Medicinal Chemistry
Y Mawani, C Orvig |
Bioinorganic Medicinal Chemistry | 2011 |
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Cation Modulation of Hemoglobin Interaction with Sodium n-Dodecyl Sulfate (SDS). II: Calcium Modulation at pH 5.0
CO Nwamba, FC Chilaka, AA Moosavi-Movahedi |
Cell Biochemistry and Biophysics | 2011 |
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Treatise on Water Science
K Kramer |
Treatise on Water Science | 2011 |
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Orally formulated artemisinin in healthy fasting vietnamese male subjects: a randomized, four-sequence, open-label, pharmacokinetic crossover study
TT Hien, W Hanpithakpong, NT Truong, NT Dung, PV Toi, J Farrar, N Lindegardh, J Tarning, M Ashton |
Clinical Therapeutics | 2011 |
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Population, behavioural and environmental drivers of malaria prevalence in the Democratic Republic of Congo
JP Messina, SM Taylor, SR Meshnick, AM Linke, AK Tshefu, B Atua, K Mwandagalirwa, M Emch |
Malaria Journal | 2011 |
|
A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine
SK Mishra, P Singh, SK Rath |
Malaria Journal | 2011 |
|
Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal
S Ranjitkar, ML Schousboe, TT Thomsen, M Adhikari, CM Kapel, IC Bygbjerg, M Alifrangis |
Malaria Journal | 2011 |
|
Seasonal and geographic differences in treatment-seeking and household cost of febrile illness among children in Malawi
VL Ewing, DG Lalloo, KS Phiri, A Roca-Feltrer, LJ Mangham, MA SanJoaquin |
Malaria Journal | 2011 |
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Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria
SA Charman, S Arbe-Barnes, IC Bathurst, R Brun, M Campbell, WN Charman, FC Chiu, J Chollet, JC Craft, DJ Creek, Y Dong, H Matile, M Maurer, J Morizzi, T Nguyen, P Papastogiannidis, C Scheurer, DM Shackleford, K Sriraghavan, L Stingelin, Y Tang, H Urwyler, X Wang, KL White, S Wittlin, L Zhou, JL Vennerstrom |
Proceedings of the National Academy of Sciences | 2011 |
|
Plasmodium vivax recurrence following falciparum and mixed species malaria: risk factors and effect of antimalarial kinetics
NM Douglas, F Nosten, EA Ashley, L Phaiphun, M Vugt, P Singhasivanon, NJ White, RN Price |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 2011 |
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Use of13C NMR Chemical Shift as QSAR/QSPR Descriptor
RP Verma, C Hansch |
Chemical Reviews | 2011 |
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Media, Health Workers, and Policy Makers' Relationship and Their Impact on Antimalarial Policy Adoption: A Population Genetics Perspective
A Malisa, R Pearce, B Mutayoba, S Abdullah, H Mshinda, P Kachur, P Bloland, C Roper |
Malaria Research and Treatment | 2011 |
|
Therapy of vector-borne protozoan infections in nonendemic settings
E Bottieau, M Vekemans, AV Gompel |
Expert Review of Anti-infective Therapy | 2011 |
|
Determinants of relapse periodicity in Plasmodium vivax malaria
NJ White |
Malaria Journal | 2011 |
|
Metabolite identification of artemether by data-dependent accurate mass spectrometric analysis using an LTQ-Orbitrap hybrid mass spectrometer in combination with the online hydrogen/deuterium exchange technique : Metabolite identification of artemether
T Liu, F Du, F Zhu, J Xing |
Rapid Communications in Mass Spectrometry | 2011 |
|
Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum
M Goyal, A Alam, MS Iqbal, S Dey, S Bindu, C Pal, A Banerjee, S Chakrabarti, U Bandyopadhyay |
Nucleic Acids Research | 2011 |
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Declining Responsiveness of Plasmodium falciparum Infections to Artemisinin-Based Combination Treatments on the Kenyan Coast
S Borrmann, P Sasi, L Mwai, M Bashraheil, A Abdallah, S Muriithi, H Frühauf, B Schaub, J Pfeil, J Peshu, W Hanpithakpong, A Rippert, E Juma, B Tsofa, M Mosobo, B Lowe, F Osier, G Fegan, N Lindegårdh, A Nzila, N Peshu, M Mackinnon, K Marsh |
PloS one | 2011 |
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Five Years of Antimalarial Resistance Marker Surveillance in Gaza Province, Mozambique, Following Artemisinin-Based Combination Therapy Roll Out
J Raman, K Mauff, P Muianga, A Mussa, R Maharaj, KI Barnes |
PloS one | 2011 |
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The Next Opportunity in Anti-Malaria Drug Discovery: The Liver Stage
ER Derbyshire, MM Mota, J Clardy |
PLoS pathogens | 2011 |
|
Molecular markers of anti-malarial drug resistance in Lahj Governorate, Yemen: baseline data and implications
RA Mubjer, AA Adeel, ML Chance, AA Hassan |
Malaria Journal | 2011 |
|
The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy
AF Read, T Day, S Huijben |
Proceedings of the National Academy of Sciences | 2011 |
|
Pharmacokinetics, Pharmacodynamics, and Allometric Scaling of Chloroquine in a Murine Malaria Model▿
BR Moore, M Page-Sharp, JR Stoney, KF Ilett, JD Jago, KT Batty |
Antimicrobial agents and chemotherapy | 2011 |
|
Redox-active antiparasitic drugs
C Pal, U Bandyopadhyay |
Antioxidants & Redox Signaling | 2011 |
|
In vivo antimalarial activity of ginseng extracts
H Han, Y Chen, H Bi, L Yu, C Sun, S Li, SA Oumar, Y Zhou |
Pharmaceutical Biology | 2011 |
|
Malaria parasite carbonic anhydrase: inhibition of aromatic/heterocyclic sulfonamides and its therapeutic potential
SR Krungkrai, J Krungkrai |
Asian Pacific Journal of Tropical Biomedicine | 2011 |
|
Quality of chloroquine tablets available in Africa
CW Sawadogo, MA Al-Kamarany, HM Al-Mekhlafi, M Elkarbane, AH Al-Adhroey, Y Cherrah, A Bouklouze |
Annals of Tropical Medicine and Parasitology | 2011 |
|
Population biological principles of drug-resistance evolution in infectious diseases
PA Wiesch, R Kouyos, J Engelstädter, RR Regoes, S Bonhoeffer |
The Lancet Infectious Diseases | 2011 |
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Plasmodium berghei K173: Selection of resistance to naphthoquine in a mouse model
H Wang, ZC Bei, JY Wang, WC Cao |
Experimental Parasitology | 2011 |
|
Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation
S Vargas, KN Ioset, AE Hay, JR Ioset, S Wittlin, K Hostettmann |
Journal of Pharmaceutical and Biomedical Analysis | 2011 |
|
Novartis Malaria Initiative: best practice example of pharmaceutical industry's engagement in the fight against malaria: Novartis in the fight against malaria
G Lefèvre, AC Marrast, H Grueninger |
Annals of the New York Academy of Sciences | 2011 |
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Malaria rapid diagnostic tests in elimination settings—can they find the last parasite?
ML McMorrow, M Aidoo, SP Kachur |
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases | 2011 |
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Absorption of the novel artemisinin derivatives artemisone and artemiside: Potential application of Pheroid™ technology
JD Steyn, L Wiesner, LH du Plessis, AF Grobler, PJ Smith, WC Chan, RK Haynes, AF Kotzé |
International Journal of Pharmaceutics | 2011 |
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An automated, polymer-assisted strategy for the preparation of urea and thiourea derivatives of 15-membered azalides as potential antimalarial chemotherapeutics
A Hutinec, R Rupčić, D Žiher, KS Smith, W Milhous, W Ellis, C Ohrt, ZI Schönfeld |
Bioorganic & Medicinal Chemistry | 2011 |
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Antimalarial Mannoxanes: Hybrid Antimalarial Drugs with Outstanding Oral Activity Profiles and A Potential Dual Mechanism of Action
J Chadwick, RK Amewu, F Marti, FB Garah, R Sharma, NG Berry, PA Stocks, H Burrell-Saward, S Wittlin, M Rottmann, R Brun, D Taramelli, S Parapini, SA Ward, PM O'Neill |
ChemMedChem | 2011 |
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A theoretical application of selectable markers in bacterial episomes for a DNA cryptosystem
L Morford |
Journal of Theoretical Biology | 2011 |
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Antiprotozoal activity of chloroquinoline based chalcones
F Hayat, E Moseley, A Salahuddin, RL van Zyl, A Azam |
European Journal of Medicinal Chemistry | 2011 |
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Potential of a Khaya ivorensis – Alstonia boonei extract combination as antimalarial prophylactic remedy
RN Tepongning, L Lucantoni, CC Nasuti, GU Dori, SR Yerbanga, G Lupidi, C Marini, G Rossi, F Esposito, A Habluetzel |
Journal of Ethnopharmacology | 2011 |
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Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique
T Liu, F Du, Y Wan, F Zhu, J Xing |
Journal of Mass Spectrometry | 2011 |
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Reverse Fosmidomycin Derivatives against the Antimalarial Drug Target IspC (Dxr)
CT Behrendt, A Kunfermann, V Illarionova, A Matheeussen, MK Pein, T Gräwert, J Kaiser, A Bacher, W Eisenreich, B Illarionov, M Fischer, L Maes, M Groll, T Kurz |
Journal of Medicinal Chemistry | 2011 |
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Optimal Treatment Strategies for Malaria Infection
JJ Thibodeaux, TP Schlittenhardt |
Bulletin of Mathematical Biology | 2011 |
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The Traditional Medicine Spilanthes acmella, and the Alkylamides Spilanthol and Undeca-2E-ene-8,10-diynoic Acid Isobutylamide, Demonstrate In Vitro and In Vivo Antimalarial Activity: ANTI-MALARIAL ACTIVITY OF SPILANTHES ACMELLA
K Spelman, D Depoix, M McCray, E Mouray, P Grellier |
Phytotherapy Research | 2011 |
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Parasitic infections and myositis
SN El-Beshbishi, NN Ahmed, SH Mostafa, GA El-Ganainy |
Parasitology Research | 2011 |
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Molecular docking and 3D-QSAR studies of falcipain inhibitors using CoMFA, CoMSIA, and Open3DQSAR
JB Ghasemi, F Shiri |
Medicinal Chemistry Research | 2011 |
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The Next Opportunity in Anti-Malaria Drug Discovery: The Liver Stage
ER Derbyshire, MM Mota, J Clardy, GF Rall |
PLoS pathogens | 2011 |
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Novel Potent Metallocenes against Liver Stage Malaria
J Matos, FP da Cruz, É Cabrita, J Gut, F Nogueira, VE do Rosário, R Moreira, PJ Rosenthal, M Prudêncio, P Gomes |
Antimicrobial agents and chemotherapy | 2011 |
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MAOS and Medicinal Chemistry: Some Important Examples from the Last Years
NM Nascimento-Júnior, AE Kümmerle, EJ Barreiro, CA Fraga |
Molecules (Basel, Switzerland) | 2011 |
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Treatment and Prevention of Malaria
HM Staines, S Krishna |
2011 | |
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Third World Diseases
R Elliott |
2011 | |
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Drug resistance in malaria
SC Parija, I Praharaj |
Indian Journal of Medical Microbiology | 2011 |
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Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola
F Fortes, R Dimbu, P Figueiredo, Z Neto, VE do Rosário, D Lopes |
Malaria Journal | 2011 |
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Cysteamine, the Molecule Used To Treat Cystinosis, Potentiates the Antimalarial Efficacy of Artemisinin
G Min-Oo, A Fortin, JF Poulin, P Gros |
Antimicrobial agents and chemotherapy | 2010 |
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Artemisinin resistance: current status and scenarios for containment
AM Dondorp, S Yeung, L White, C Nguon, NP Day, D Socheat, L von Seidlein |
Nature Reviews Microbiology | 2010 |
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Frequency distribution of antimalarial drug resistance alleles among Plasmodium falciparum isolates from Gezira State, central Sudan, and Gedarif State, eastern Sudan
M Menegon, AA Talha, C Severini, SM Elbushra, AA Mohamedani, EM Malik, TA Mohamed, WH Wernsdorfer, G Majori, BY Nour |
The American journal of tropical medicine and hygiene | 2010 |
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Understanding caretakers' dilemma in deciding whether or not to adhere with referral advice after pre-referral treatment with rectal artesunate
DO Simba, DC Kakoko, M Warsame, Z Premji, MF Gomes, G Tomson, E Johansson |
Malaria Journal | 2010 |
|
Absorption, distribution, excretion, and pharmacokinetics of 14C-pyronaridine tetraphosphate in male and female Sprague-Dawley rats
SH Park, K Pradeep |
Journal of biomedicine & biotechnology | 2010 |
|
Markers of anti-malarial drug resistance in Plasmodium falciparum isolates from Swaziland: identification of pfmdr1-86F in natural parasite isolates
SV Dlamini, K Beshir, CJ Sutherland |
Malaria Journal | 2010 |
|
Community response to artemisinin-based combination therapy for childhood malaria: a case study from Dar es Salaam, Tanzania
VR Kamat, DJ Nyato |
Malaria Journal | 2010 |
|
Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children
A Sowunmi, EO Adewoye, GO Gbotsho, CT Happi, A Sijuade, OA Folarin, TM Okuboyejo, OS Michael |
Malaria Journal | 2010 |
|
Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy
MA Phillips, PK Rathod |
Infectious disorders drug targets | 2010 |
|
Merging traditional Chinese medicine with modern drug discovery technologies to find novel drugs and functional foods
R Graziose, MA Lila, I Raskin |
Current drug discovery technologies | 2010 |
|
Artemisinin resistance: current status and scenarios for containment
AM Dondorp, S Yeung, L White, C Nguon, NP Day, D Socheat, L Seidlein |
Nature Reviews Microbiology | 2010 |
|
Immunogenicity of the Plasmodium falciparum Pf332-DBL domain in combination with different adjuvants
C Du, S Nilsson, H Lu, J Yin, N Jiang, M Wahlgren, Q Chen |
Vaccine | 2010 |
|
Artemisinin combination therapy for vivax malaria?
NM Douglas, NM Anstey, BJ Angus, F Nosten, RN Price |
The Lancet Infectious Diseases | 2010 |
|
Binding modes of 2,4-diaminoquinazoline and 2,4-diaminopteridine analogs to P. falciparum dihydrofolate reductase enzyme: Molecular docking studies
L Adane, PV Bharatam |
Indian journal of pharmaceutical sciences | 2010 |
|
Cochrane Database of Systematic Reviews: Reviews
N Shafiq, M Singh, S Kaur, P Khosla, S Malhotra, N Shafiq |
Cochrane Database of Systematic Reviews: Reviews | 2010 |
|
Antibiotic and Chemotherapy
P Moss |
Antibiotic and Chemotherapy | 2010 |
|
Artemisinin, an anti-malarial agent, inhibits rat cardiac hypertrophy via inhibition of NF-κB signaling
Z Xiong, G Sun, C Zhu, B Cheng, C Zhang, Y Ma, Y Dong |
European Journal of Pharmacology | 2010 |
|
Combination therapy for visceral leishmaniasis
J Griensven, M Balasegaram, F Meheus, J Alvar, L Lynen, M Boelaert |
The Lancet Infectious Diseases | 2010 |
|
Malaria in children
J Crawley, C Chu, G Mtove, F Nosten |
The Lancet | 2010 |
|
Chemotherapeutic interaction between Khaya grandifoliola (WELW) CDC stem bark extract and two anti-malarial drugs in mice
SO Ijarotimi, JM Agbedahunsi, CO Onyeji, CO Adewunmi |
African Journal of Traditional, Complementary, and Alternative Medicines | 2010 |
|
Gomphostenins: Two new antimalarial compounds from the leaves of Gomphostemma niveum
M Sathe, MP Kaushik |
Bioorganic & Medicinal Chemistry Letters | 2010 |
|
Only the good die young: a novel paradigm for mosquito control
PF Billingsley |
Trends in Parasitology | 2010 |
|
Comparative oral bioavailability of non-fixed and fixed combinations of artesunate and amodiaquine in healthy Indian male volunteers
A Fortin, RK Verbeeck, FH Jansen |
European Journal of Clinical Pharmacology | 2010 |
|
Shape- and Chemical Feature-Based 3D-Pharmacophore Model Generation and Virtual Screening: Identification of Potential Leads for P. falciparum DHFR Enzyme Inhibition
L Adane, DS Patel, PV Bharatam |
Chemical Biology & Drug Design | 2010 |
|
Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols
R Amewu, P Gibbons, A Mukhtar, AV Stachulski, SA Ward, C Hall, K Rimmer, J Davies, L Vivas, J Bacsa, AE Mercer, G Nixon, PA Stocks, PM O'Neill |
Organic & Biomolecular Chemistry | 2010 |
|
Soft targets or partners in health? Retail pharmacies and their role in Tanzania’s malaria control program
VR Kamat, DJ Nyato |
Social Science & Medicine | 2010 |
|
Molecular surveillance of drug-resistant Plasmodium falciparum in two distinct geographical areas of Nigeria
O Ojurongbe, SI Oyedeji, WA Oyibo, AF Fagbenro-Beyioku, JF Kun |
Wiener klinische Wochenschrift | 2010 |
|
Identification of a 1,2,4,5-Tetraoxane Antimalarial Drug-Development Candidate (RKA 182) with Superior Properties to the Semisynthetic Artemisinins
PM O'Neill, RK Amewu, GL Nixon, F Bousejra ElGarah, M Mungthin, J Chadwick, AE Shone, L Vivas, H Lander, V Barton, S Muangnoicharoen, PG Bray, J Davies, BK Park, S Wittlin, R Brun, M Preschel, K Zhang, SA Ward |
Angewandte Chemie (International ed. in English) | 2010 |
|
Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials
X Deng, A Nagle, T Wu, T Sakata, K Henson, Z Chen, K Kuhen, D Plouffe, E Winzeler, F Adrian, T Tuntland, J Chang, S Simerson, S Howard, J Ek, J Isbell, DC Tully, AK Chatterjee, NS Gray |
Bioorganic & Medicinal Chemistry Letters | 2010 |
|
Investigation of reproductive toxicity of piperaquine in mice
KT Batty, BR Moore, V Stirling, KF Ilett, M Page-Sharp, KB Shilkin, I Mueller, SJ Rogerson, HA Karunajeewa, TM Davis |
Reproductive Toxicology | 2010 |
|
Child age or weight: difficulties related to the prescription of the right dosage of antimalarial combinations to treat children in Senegal
A Souares, R Lalou, P Senghor, JY Hesran |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2010 |
|
An analytical model for genetic hitchhiking in the evolution of antimalarial drug resistance
KA Schneider, Y Kim |
Theoretical Population Biology | 2010 |
|
In Vivo Parasitological Measures of Artemisinin Susceptibility
K Stepniewska, E Ashley, SJ Lee, N Anstey, KI Barnes, TQ Binh, U D’Alessandro, NP Day, PJ Vries, G Dorsey, JP Guthmann, M Mayxay, PN Newton, P Olliaro, L Osorio, RN Price, M Rowland, F Smithuis, WR Taylor, F Nosten, NJ White |
The Journal of Infectious Diseases | 2010 |
|
Synthesis of novel α-pyranochalcones and pyrazoline derivatives as Plasmodium falciparum growth inhibitors
G Wanare, R Aher, N Kawathekar, R Ranjan, NK Kaushik, D Sahal |
Bioorganic & Medicinal Chemistry Letters | 2010 |
|
Ethnopharmacological use of herbal remedies for the treatment of malaria in the Dangme West District of Ghana
A Asase, GA Akwetey, DG Achel |
Journal of Ethnopharmacology | 2010 |
|
Selection of pfmdr1 and pfcrt alleles in amodiaquine treatment failure in north-western Burkina Faso
I Danquah, B Coulibaly, P Meissner, I Petruschke, O Müller, FP Mockenhaupt |
Acta Tropica | 2010 |
|
Immunogenic properties of a recombinant fusion protein containing the C-terminal 19kDa of Plasmodium falciparum merozoite surface protein-1 and the innate immunity agonist FliC flagellin of Salmonella Typhimurium
DY Bargieri, JA Leite, SC Lopes, ME Sbrogio-Almeida, CJ Braga, LC Ferreira, IS Soares, FT Costa, MM Rodrigues |
Vaccine | 2010 |
|
Should new antimalarial drugs be subsidized?
R Laxminarayan, IW Parry, DL Smith, EY Klein |
Journal of Health Economics | 2010 |
|
Visual characterization of targeted effect of holo-transferrin-tagged dihydroartemisinin on human breast cancer cells
WL Xie, PH Yang, X Zeng, H Wang, HH Cai, JY Cai |
Chinese Science Bulletin | 2010 |
|
Identification of a 1,2,4,5-Tetraoxane Antimalarial Drug-Development Candidate (RKA 182) with Superior Properties to the Semisynthetic Artemisinins
PM O'Neill, RK Amewu, GL Nixon, F Bousejra ElGarah, M Mungthin, J Chadwick, AE Shone, L Vivas, H Lander, V Barton, S Muangnoicharoen, PG Bray, J Davies, BK Park, S Wittlin, R Brun, M Preschel, K Zhang, SA Ward |
Angewandte Chemie | 2010 |
|
Artemisinin resistance or tolerance in human malaria patients
J Krungkrai, W Imprasittichai, S Otjungreed, S Pongsabut, SR Krungkrai |
Asian Pacific Journal of Tropical Medicine | 2010 |
|
Formulation optimization of dihydroartemisinin nanostructured lipid carrier using response surface methodology
X Zhang, J Liu, H Qiao, H Liu, J Ni, W Zhang, Y Shi |
Powder Technology | 2010 |
|
In vivo antimalarial activities of glycoalkaloids isolated from Solanaceae plants
Y Chen, S Li, F Sun, H Han, X Zhang, Y Fan, G Tai, Y Zhou |
Pharmaceutical Biology | 2010 |
|
Frequency Distribution of Antimalarial Drug Resistance Alleles among Plasmodium falciparum Isolates from Gezira State, Central Sudan, and Gedarif State, Eastern Sudan
G Majori, AA Talha, M Menegon, BY Nour, SM Elbushra, C Severini, EM Malik, AA Mohamedani, WH Wernsdorfer, TA Mohamed |
The American journal of tropical medicine and hygiene | 2010 |
|
Solubility of Artemisinin in Different Single and Binary Solvent Mixtures Between (284.15 and 323.15) K and NRTL Interaction Parameters
J Nti-Gyabaah, K Gbewonyo, YC Chiew |
Journal of Chemical & Engineering Data | 2010 |
|
Understanding Chloroquine Action at the Molecular Level in Antimalarial Therapy: X-ray Absorption Studies in Dimethyl Sulfoxide Solution
MS Walczak, K Lawniczak-Jablonska, A Wolska, A Sienkiewicz, L Suárez, AJ Kosar, DS Bohle |
The Journal of Physical Chemistry B | 2010 |
|
Falciparum Malaria
Feldman C, Richards GA |
2010 | |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
|
Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds
X Deng, R Gujjar, FE Mazouni, W Kaminsky, NA Malmquist, EJ Goldsmith, PK Rathod, MA Phillips |
The Journal of biological chemistry | 2009 |
|
Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis
S Dey, M Guha, A Alam, M Goyal, S Bindu, C Pal, P Maity, K Mitra, U Bandyopadhyay |
Free radical biology & medicine | 2009 |
|
Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice
R Gujjar, A Marwaha, FE Mazouni, J White, KL White, S Creason, DM Shackleford, J Baldwin, WN Charman, FS Buckner, S Charman, PK Rathod, MA Phillips |
Journal of Medicinal Chemistry | 2009 |
|
Falcipain-2 inhibitors
R Ettari, F Bova, M Zappalà, S Grasso, N Micale |
Medicinal Research Reviews | 2009 |
|
Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials
BT Grimberg, MM Jaworska, LB Hough, PA Zimmerman, JG Phillips |
Bioorganic & Medicinal Chemistry Letters | 2009 |
|
In vitro selection of Plasmodium falciparum drug-resistant parasite lines
A Nzila, L Mwai |
The Journal of antimicrobial chemotherapy | 2009 |
|
Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial
Q Bassat, M Mulenga, H Tinto, P Piola, S Borrmann, C Menéndez, M Nambozi, I Valéa, C Nabasumba, P Sasi, A Bacchieri, M Corsi, D Ubben, A Talisuna, U D'Alessandro |
PloS one | 2009 |
|
Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance
NJ White, W Pongtavornpinyo, RJ Maude, S Saralamba, R Aguas, K Stepniewska, SJ Lee, AM Dondorp, LJ White, NP Day |
Malaria Journal | 2009 |
|
Ongoing challenges in the management of malaria
G Kokwaro |
Malaria Journal | 2009 |
|
Chloroquine resistance before and after its withdrawal in Kenya
L Mwai, E Ochong, A Abdirahman, SM Kiara, S Ward, G Kokwaro, P Sasi, K Marsh, S Borrmann, M Mackinnon, A Nzila |
Malaria Journal | 2009 |
|
The origins of apicomplexan sequence innovation
J Wasmuth, J Daub, JM Peregrín-Alvarez, CA Finney, J Parkinson |
Genome research | 2009 |
|
Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model
DM Kiboi, BN Irungu, B Langat, S Wittlin, R Brun, J Chollet, O Abiodun, JK Nganga, VC Nyambati, GM Rukunga, A Bell, A Nzila |
Experimental Parasitology | 2009 |
|
Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases
Y Zhang, M Luo, VL Schramm |
Journal of the American Chemical Society | 2009 |
|
Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger
ML Ibrahim, N Steenkeste, N Khim, HH Adam, L Konaté, JY Coppée, F Ariey, JB Duchemin |
Malaria Journal | 2009 |
|
The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia
RJ Maude, W Pontavornpinyo, S Saralamba, R Aguas, S Yeung, AM Dondorp, NP Day, NJ White, LJ White |
Malaria Journal | 2009 |
|
Waiting longer for two mutations
MJ Behe |
Genetics | 2009 |
|
Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia
WO Rogers, R Sem, T Tero, P Chim, P Lim, S Muth, D Socheat, F Ariey, C Wongsrichanalai |
Malaria Journal | 2009 |
|
Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women
A Mayor, E Serra-Casas, A Bardají, S Sanz, L Puyol, P Cisteró, B Sigauque, I Mandomando, JJ Aponte, PL Alonso, C Menéndez |
Malaria Journal | 2009 |
|
Detection of Artemisinin-resistant Plasmodium falciparum in Malarial Infection: A Brief Review of Methods
NB Quashie |
Journal of Tropical Pediatrics | 2009 |
|
PERSPECTIVE: Evolutionary biology and the avoidance of antimicrobial resistance: Evolutionary biology and the avoidance of antimicrobial resistance
AF Read, S Huijben |
Evolutionary Applications | 2009 |
|
Organocatalyzed highly atom economic one pot synthesis of tetrahydropyridines as antimalarials
M Misra, SK Pandey, VP Pandey, J Pandey, R Tripathi, RP Tripathi |
Bioorganic & Medicinal Chemistry | 2009 |
|
Factors influencing adherence to referral advice following pre-referral treatment with artesunate suppositories in children in rural Tanzania
DO Simba, M Warsame, O Kimbute, D Kakoko, M Petzold, G Tomson, Z Premji, M Gomes |
Tropical Medicine & International Health | 2009 |
|
Malaria treatment: no place like home
F Pagnoni |
Trends in Parasitology | 2009 |
|
α-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases
KM Orrling, MR Marzahn, H Gutiérrez-de-Terán, J Åqvist, BM Dunn, M Larhed |
Bioorganic & Medicinal Chemistry | 2009 |
|
Two complementary fluorimetric assays for the determination of aminoquinoline binding and uptake by human erythrocytes in vitro
N Basilico, L Cortelezzi, C Serpellini, D Taramelli, FO Salè |
Analytical Biochemistry | 2009 |
|
Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine for Treating Uncomplicated Malaria in African Children: A Randomised, Non-Inferiority Trial
Q Bassat, M Mulenga, H Tinto, P Piola, S Borrmann, C Menéndez, M Nambozi, I Valéa, C Nabasumba, P Sasi, A Bacchieri, M Corsi, D Ubben, A Talisuna, U D'Alessandro, KI Barnes |
PloS one | 2009 |
|
New 1-Aryl-3-Substituted Propanol Derivatives as Antimalarial Agents
S Pérez-Silanes, L Berrade, R GarcíaSánchez, A Mendoza, S Galiano, B Pérez-Solórzano, J Nogal-Ruiz, A Martínez-Fernández, I Aldana, A Monge |
Molecules (Basel, Switzerland) | 2009 |
|
A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria
S Picot, P Olliaro, F de Monbrison, AL Bienvenu, RN Price, P Ringwald |
Malaria Journal | 2009 |
|
Application of the linear interaction energy method for rational design of artemisinin analogues as haeme polymerisation inhibitors
M Srivastava, H Singh, PK Naik |
SAR and QSAR in Environmental Research | 2009 |
|
Herbal Drugs: Ethnomedicine to Modern Medicine
KG Ramawat |
2009 | |
|
Antimicrobial Resistance in Developing Countries
A de J. Sosa, DK Byarugaba, CF Amábile-Cuevas, PR Hsueh, S Kariuki, IN Okeke |
2009 | |
|
Novel Antimalarial Aminoquinolines: Heme Binding and Effects on Normal or Plasmodium falciparum -Parasitized Human Erythrocytes
F Omodeo-Salè, L Cortelezzi, N Basilico, M Casagrande, A Sparatore, D Taramelli |
Antimicrobial agents and chemotherapy | 2009 |
|
Identification of Novel Falcipain-2 Inhibitors as Potential Antimalarial Agents through Structure-Based Virtual Screening
H Li, J Huang, L Chen, X Liu, T Chen, J Zhu, W Lu, X Shen, J Li, R Hilgenfeld, H Jiang |
Journal of Medicinal Chemistry | 2009 |
|
A Topological Study of the Decomposition of 6,7,8-Trioxabicyclo[3.2.2]nonane Induced by Fe(II): Modeling the Artemisinin Reaction with Heme
P Moles, M Oliva, Á Sánchez-González, VS Safont |
The Journal of Physical Chemistry B | 2009 |
|
Identification and Characterization of Novel Small Molecules as Potent Inhibitors of the Plasmodial Calcium-Dependent Protein Kinase 1
G Lemercier, A Fernandez-Montalvan, JP Shaw, D Kugelstadt, J Bomke, M Domostoj, MK Schwarz, A Scheer, B Kappes, D Leroy |
Biochemistry | 2009 |
|
Combining Asymmetric Catalysis with Natural Product Functionalization through Enantioselective α-Fluorination
J Erb, E Alden-Danforth, N Kopf, MT Scerba, T Lectka |
The Journal of Organic Chemistry | 2009 |
|
Evaluation of Artemisone Combinations in Aotus Monkeys Infected with Plasmodium falciparum
N Obaldia, BM Kotecka, MD Edstein, RK Haynes, B Fugmann, DE Kyle, KH Rieckmann |
Antimicrobial agents and chemotherapy | 2009 |
|
MALARIA: PROGRESS, PERILS, AND PROSPECTS FOR ERADICATION
Brian M. Greenwood , David A. Fidock , Dennis E. Kyle , Stefan H. I. Kappe , Pedro L. Alonso , Frank H. Collins , Patrick E. Duffy4* |
Journal of Clinical Investigation | 2008 |
|
Benefits of using multiple first-line therapies against malaria
MF Boni, DL Smith, R Laxminarayan |
Proceedings of the National Academy of Sciences | 2008 |
|
Artemisinins: their growing importance in medicine
S Krishna, L Bustamante, RK Haynes, HM Staines |
Trends in Pharmacological Sciences | 2008 |
|
Molecular epidemiology of drug-resistant malaria in western Kenya highlands
D Zhong, Y Afrane, A Githeko, L Cui, DM Menge, G Yan |
BMC Infectious Diseases | 2008 |
|
Early home treatment of childhood fevers with ineffective antimalarials is deleterious in the outcome of severe malaria
AE Orimadegun, OK Amodu, PE Olumese, OO Omotade |
Malaria Journal | 2008 |
|
The impact of HIV-1 on the malaria parasite biomass in adults in sub-Saharan Africa contributes to the emergence of antimalarial drug resistance
JP Geertruyden, J Menten, R Colebunders, E Korenromp, U D'Alessandro |
Malaria Journal | 2008 |
|
Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials
LC Okell, CJ Drakeley, AC Ghani, T Bousema, CJ Sutherland |
Malaria Journal | 2008 |
|
Antimalarial drug use in general populations of tropical Africa
F Gardella, S Assi, F Simon, H Bogreau, T Eggelte, F Ba, V Foumane, MC Henry, PT Kientega, L Basco, JF Trape, R Lalou, M Martelloni, M Desbordes, M Baragatti, S Briolant, L Almeras, B Pradines, T Fusai, C Rogier |
Malaria Journal | 2008 |
|
Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana
M Cairns, I Carneiro, P Milligan, S Owusu-Agyei, T Awine, R Gosling, B Greenwood, D Chandramohan |
PloS one | 2008 |
|
Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: up-dated baseline data from randomized and multi-site clinical trials
D Ménard, A Ratsimbasoa, M Randrianarivelojosia, LP Rabarijaona, L Raharimalala, O Domarle, L Randrianasolo, A Randriamanantena, M Jahevitra, V Andriantsoanirina, MA Rason, R Raherinjafy, E Rakotomalala, L Tuseo, A Raveloson |
Malaria Journal | 2008 |
|
Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites
IO Ajayi, EN Browne, B Garshong, F Bateganya, B Yusuf, P Agyei-Baffour, L Doamekpor, A Balyeku, K Munguti, S Cousens, F Pagnoni |
Malaria Journal | 2008 |
|
Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugation
I Nakase, H Lai, NP Singh, T Sasaki |
International Journal of Pharmaceutics | 2008 |
|
Molecular Markers of Resistance to Sulfadoxine‐Pyrimethamine during Intermittent Preventive Treatment for Malaria in Mozambican Infants
A Mayor, E Serra‐Casas, S Sanz, JJ Aponte, E Macete, I Mandomando, L Puyol, P Berzosa, C Dobaño, P Aide, J Sacarlal, A Benito, P Alonso, C Menéndez |
The Journal of Infectious Diseases | 2008 |
|
Amodiaquine pharmacogenetics
JP Gil |
Pharmacogenomics | 2008 |
|
Pharmacogenetic tools for malaria and TB in the Developing World
PE Ferreira, I Cavaco, JP Gil |
Personalized Medicine | 2008 |
|
Clinical Pharmacology of Artemisinin-Based Combination Therapies:
FT Aweeka, PI German |
Clinical Pharmacokinetics | 2008 |
|
Differential effect of regional drug pressure on dihydrofolate reductase and dihydropteroate synthetase mutations in southern Mozambique
J Raman, B Sharp, I Kleinschmidt, C Roper, E Streat, V Kelly, KI Barnes |
The American journal of tropical medicine and hygiene | 2008 |
|
Spatial distribution of heme species in erythrocytes infected with Plasmodium falciparum by use of resonance Raman imaging and multivariate analysis
A Bonifacio, S Finaurini, C Krafft, S Parapini, D Taramelli, V Sergo |
Analytical and Bioanalytical Chemistry | 2008 |
|
High frequency of Plasmodium falciparum CICNI/SGEAA and CVIET haplotypes without association with resistance to sulfadoxine/pyrimethamine and chloroquine combination in the Daraweesh area, in Sudan
IE A-Elbasit, IF Khalil, MI Elbashir, EM Masuadi, IC Bygbjerg, M Alifrangis, HA Giha |
European Journal of Clinical Microbiology & Infectious Diseases | 2008 |
|
Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies
JR Lenihan, H Tsuruta, D Diola, NS Renninger, R Regentin |
Biotechnology Progress | 2008 |
|
Atovaquone-Statine “Double-Drugs” with High Antiplasmodial Activity
S Romeo, S Parapini, M Dell'Agli, N Vaiana, P Magrone, G Galli, A Sparatore, D Taramelli, E Bosisio |
ChemMedChem | 2008 |
|
Carbonic anhydrase inhibitors: Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides—in vitro and in vivo studies
J Krungkrai, SR Krungkrai, CT Supuran |
Bioorganic & Medicinal Chemistry Letters | 2008 |
|
A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens
DA Elsherbiny, SA Asimus, MO Karlsson, M Ashton, US Simonsson |
Journal of Pharmacokinetics and Pharmacodynamics | 2008 |
|
Adherence and effectiveness of drug combination in curative treatment among children suffering uncomplicated malaria in rural Senegal
A Souares, R Lalou, I Sene, D Sow, JY Hesran |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2008 |
|
Design, synthesis and antimalarial activity of benzene and isoquinoline sulfonamide derivatives
MK Parai, G Panda, K Srivastava, SK Puri |
Bioorganic & Medicinal Chemistry Letters | 2008 |
|
Antimalarial Drugs – What is in Use and What is in the Pipeline
M Schlitzer |
Archiv der Pharmazie | 2008 |
|
Antimalarial dosing regimens and drug resistance
KI Barnes, WM Watkins, NJ White |
Trends in Parasitology | 2008 |
|
Marked differences in the prevalence of chloroquine resistance between urban and rural communities in Burkina Faso
PE Meissner, G Mandi, FP Mockenhaupt, S Witte, B Coulibaly, U Mansmann, C Frey, H Merkle, J Burhenne, I Walter-Sack, O Müller |
Acta Tropica | 2008 |
|
Simplified antimalarial therapeutic monitoring: using the day-7 drug level?
NJ White, K Stepniewska, K Barnes, RN Price, J Simpson |
Trends in Parasitology | 2008 |
|
Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo
L Vivas, L Rattray, L Stewart, E Bongard, BL Robinson, W Peters, SL Croft |
Acta Tropica | 2008 |
|
Antimalarial quinolones: Synthesis, potency, and mechanistic studies
RW Winter, JX Kelly, MJ Smilkstein, R Dodean, D Hinrichs, MK Riscoe |
Experimental Parasitology | 2008 |
|
Accumulation of the antimalarial microtubule inhibitors trifluralin and vinblastine by Plasmodium falciparum
JA Naughton, R Hughes, P Bray, A Bell |
Biochemical Pharmacology | 2008 |
|
Chloroquine Phosphate Potentiates Indomethacin and HCl/Ethanol-Induced Gastric Mucosa Injury in Rats
KO Ajeigbe, EO Nwobodo, TO Oyesola, DA Ofusori, SB Olaleye |
International Journal of Pharmacology | 2008 |
|
Dying under the Bird's Shadow: Narrative Representations of Degedege and Child Survival among the Zaramo of Tanzania
VR Kamat |
Medical Anthropology Quarterly | 2008 |
|
A theoretical study on the decomposition mechanism of artemisinin
P Moles, M Oliva, VS Safont |
Tetrahedron | 2008 |
|
Design, synthesis, and antimalarial evaluation of thiazole-derived amino acids
HN Karade, BN Acharya, M Sathe, MP Kaushik |
Medicinal Chemistry Research | 2008 |
|
Effects of amodiaquine hydrochloride and artemisinin on indomethacin-induced lipid peroxidation in rats
K O Ajeigbe, S B Olaleye, E O Nwobodo |
Pakistan journal of biological sciences: PJBS | 2008 |
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Synthesis and Evaluation of Non-peptidic Cysteine Protease Inhibitors of P. falciparum Derived from Etacrynic Acid
MA Dude, U Kaeppler, M Herb, M Schiller, F Schulz, B Vedder, S Heppner, G Pradel, J Gut, PJ Rosenthal, T Schirmeister, M Leippe, C Gelhaus |
Molecules (Basel, Switzerland) | 2008 |
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Duration of Protection against Malaria and Anaemia Provided by Intermittent Preventive Treatment in Infants in Navrongo, Ghana
M Cairns, I Carneiro, P Milligan, S Owusu-Agyei, T Awine, R Gosling, B Greenwood, D Chandramohan, NJ White |
PloS one | 2008 |
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Liquid Chromatography Time-of-Flight Mass Spectrometry: Principles, Tools, and Applications for Accurate Mass Analysis
I Ferrer, EM Thurman |
2008 | |
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Working without a blindfold: the critical role of diagnostics in malaria control
MD Perkins, DR Bell |
Malaria Journal | 2008 |
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The role of anti-malarial drugs in eliminating malaria
NJ White |
Malaria Journal | 2008 |
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Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola
P Figueiredo, C Benchimol, D Lopes, L Bernardino, VE do Rosário, L Varandas, F Nogueira |
Malaria Journal | 2008 |
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Antiplasmodial Activity of [(Aryl)arylsulfanylmethyl]Pyridine
S Kumar, SK Das, S Dey, P Maity, M Guha, V Choubey, G Panda, U Bandyopadhyay |
Antimicrobial agents and chemotherapy | 2008 |
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Inhibition of Malaria Parasite Development by a Cyclic Peptide That Targets the Vital Parasite Protein SERA5
WD Fairlie, TP Spurck, JE McCoubrie, PR Gilson, SK Miller, GI McFadden, R Malby, BS Crabb, AN Hodder |
Infection and immunity | 2008 |
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Biochemical and Genetic Analysis of the Phosphoethanolamine Methyltransferase of the Human Malaria Parasite Plasmodium falciparum
JM Reynolds, S Takebe, JY Choi, KE Bissati, WH Witola, AM Bobenchik, JC Hoch, DR Voelker, CB Mamoun |
The Journal of biological chemistry | 2008 |
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First Assessment in Humans of the Safety, Tolerability, Pharmacokinetics, and Ex Vivo Pharmacodynamic Antimalarial Activity of the New Artemisinin Derivative Artemisone
J Nagelschmitz, B Voith, G Wensing, A Roemer, B Fugmann, RK Haynes, BM Kotecka, KH Rieckmann, MD Edstein |
Antimicrobial agents and chemotherapy | 2008 |
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Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitors with Potent and Selective Activity against the Malaria Parasite Plasmodium falciparum
MA Phillips, R Gujjar, NA Malmquist, J White, FE Mazouni, J Baldwin, PK Rathod |
Journal of Medicinal Chemistry | 2008 |
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Pharmacokinetic Determinants of the Window of Selection for Antimalarial Drug Resistance
K Stepniewska, NJ White |
Antimicrobial agents and chemotherapy | 2008 |
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Characterization of "Yaa Chud" Medicine on the Thailand-Myanmar border: selecting for drug-resistant malaria and threatening public health
Paul N Newton, Christina Y Hampton, Krystyn Alter-Hall, Thanongsak Teerwarakulpana, Sompol Prakongpan, Ronnatrai Ruangveerayuth, Nicholas J White, Nicholas P J Day, Mabel B Tudino, Natalia Mancuso, Facundo M Fernández |
The American journal of tropical medicine and hygiene | 2008 |
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Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial.
Gomes MF, Faiz MA, Gyapong JO, Warsame M, Agbenyega T, Babiker A, Baiden F, Yunus EB, Binka F, Clerk C, Folb P, Hassan R, Hossain MA, Kimbute O, Kitua A, Krishna S, Makasi C, Mensah N, Mrango Z, Olliaro P, Peto R, Peto TJ, Rahman MR, Ribeiro I, Samad R, White NJ |
2008 | |
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Anti-Inflammatory Properties and Regulatory Mechanism of a Novel Derivative of Artemisinin in Experimental Autoimmune Encephalomyelitis
Z Wang, J Qiu, TB Guo, A Liu, Y Wang, Y Li, JZ Zhang |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
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Structural RNAs of known and unknown function identified in malaria parasites by comparative genomics and RNA analysis
K Chakrabarti, M Pearson, L Grate, T Sterne-Weiler, J Deans, JP Donohue, M Ares |
RNA (New York, N.Y.) | 2007 |
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The rationale and plan for creating a World Antimalarial Resistance Network (WARN)
CH Sibley, KI Barnes, CV Plowe |
Malaria Journal | 2007 |
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Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar
D Ménard, NN Andrianina, Z Ramiandrasoa, A Randriamanantena, N Rasoarilalao, M Jahevitra, A Ratsimbasoa, L Tuseo, A Raveloson |
Malaria Journal | 2007 |
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Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventions
TO Abuya, W Mutemi, B Karisa, SA Ochola, G Fegan, V Marsh |
Malaria Journal | 2007 |
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Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use
N Noranate, R Durand, A Tall, L Marrama, A Spiegel, C Sokhna, B Pradines, S Cojean, M Guillotte, E Bischoff, MT Ekala, C Bouchier, T Fandeur, F Ariey, J Patarapotikul, JL Bras, JF Trape, C Rogier, O Mercereau-Puijalon |
PloS one | 2007 |
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Targeting purine and pyrimidine metabolism in human apicomplexan parasites
JE Hyde |
Current drug targets | 2007 |
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Dose ranging studies of new artemisinin-piperaquine fixed combinations compared to standard regimens of artemisisnin combination therapies for acute uncomplicated falciparum malaria
S Krudsood, N Tangpukdee, V Thanchatwet, P Wilairatana, S Srivilairit, N Pothipak, S Jianping, L Guoqiao, GM Brittenham, S Looareesuwan |
The Southeast Asian journal of tropical medicine and public health | 2007 |
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In vitro Interaktionsstudien mit Azithromycin und Dihydroartemisinin in Plasmodium falciparum Isolaten aus Bangladesh
MG Vossen, R Haque, P Starzengruber, WA Khan, K Thriemer, AS Marma, S Akther, M Fukuda, H Noedl |
Wiener klinische Wochenschrift | 2007 |
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Antimicrobial prevention and therapy for travelers’ infection
F Castelli, S Capone, B Pedruzzi, A Matteelli |
Expert Review of Anti-infective Therapy | 2007 |
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Malaria Chemotherapeutics Part I: History of Antimalarial Drug Development, Currently Used Therapeutics, and Drugs in Clinical Development
M Schlitzer |
ChemMedChem | 2007 |
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The Fe2+-Mediated Decomposition, PfATP6 Binding, and Antimalarial Activities of Artemisone and Other Artemisinins: The Unlikelihood of C-Centered Radicals as Bioactive Intermediates
RK Haynes, WC Chan, CM Lung, AC Uhlemann, U Eckstein, D Taramelli, S Parapini, D Monti, S Krishna |
ChemMedChem | 2007 |
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Randomized Comparison of Amodiaquine plus Sulfadoxine-Pyrimethamine, Artemether-Lumefantrine, and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Burkina Faso
I Zongo, G Dorsey, N Rouamba, C Dokomajilar, Y Sere, PJ Rosenthal, JB Ouedraogo |
Clinical Infectious Diseases | 2007 |
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Antimalarial Cation-dimers Synthesized in Two Steps from an Inexpensive Starting Material, Isonicotinic Acid
K Motoshima, Y Hiwasa, M Yoshikawa, K Fujimoto, A Tai, H Kakuta, K Sasaki |
ChemMedChem | 2007 |
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A study on antimalarial artemisinin derivatives using MEP maps and multivariate QSAR
FJ Cardoso, AF Figueiredo, MS Lobato, RM Miranda, RC Almeida, JC Pinheiro |
Journal of Molecular Modeling | 2007 |
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Treatment of childhood Plasmodium falciparum malaria: current challenges
DJ Bell, ME Molyneux |
Expert Review of Anti-infective Therapy | 2007 |
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Wilderness Medicine
PH Hackett, RC Roach |
Wilderness Medicine | 2007 |
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Antimalarial drug combinations in vastly different settings
RH Morrow |
The Lancet | 2007 |
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Proteome analysis of new antimalarial endoperoxide against Plasmodium falciparum
NS Aly, A Hiramoto, H Sanai, O Hiraoka, K Hiramoto, H Kataoka, JM Wu, A Masuyama, M Nojima, S Kawai, HS Kim, Y Wataya |
Parasitology Research | 2007 |
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Evaluation of the safety and relative bioavailability of a new dihydroartemisinin tablet formulation in healthy Thai volunteers
S Kongpatanakul, S Chatsiricharoenkul, K Sathirakul, Y Suputtamongkol, S Atipas, S Watnasirichaikul, P Pongnarin, P Sangvanich |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2007 |
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Different doses of amodiaquine and chloroquine for treatment of uncomplicated malaria in children in Guinea-Bissau: implications for future treatment recommendations
PE Kofoed, J Ursing, A Poulsen, A Rodrigues, Y Bergquist, P Aaby, L Rombo |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2007 |
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Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase
RT Eastman, J White, O Hucke, K Yokoyama, CL Verlinde, MA Hast, LS Beese, MH Gelb, PK Rathod, WC van Voorhis |
Molecular and Biochemical Parasitology | 2007 |
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Synthesis and evaluation of sulfonylurea derivatives as novel antimalarials
C León, J Rodrigues, NG de Domínguez, J Charris, J Gut, PJ Rosenthal, JN Domínguez |
European Journal of Medicinal Chemistry | 2007 |
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Delayed parasite elimination in human infections treated with clindamycin parallels ‘delayed death’ of Plasmodium falciparum in vitro
D Burkhardt, J Wiesner, N Stoesser, M Ramharter, AC Uhlemann, S Issifou, H Jomaa, S Krishna, PG Kremsner, S Borrmann |
International Journal for Parasitology | 2007 |
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An update on malaria prevention, diagnosis and treatment for the returning traveller
E Gkrania-Klotsas, AM Lever |
Blood Reviews | 2007 |
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Novel molecular targets for antimalarial chemotherapy
S Jana, J Paliwal |
International Journal of Antimicrobial Agents | 2007 |
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Suppressive effects of the anti-oxidant N-acetylcysteine on the anti-malarial activity of artesunate
P Arreesrisom, AM Dondorp, S Looareesuwan, R Udomsangpetch |
Parasitology International | 2007 |
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Review on antimalarial drug resistance
P Ringwald |
Médecine et Maladies Infectieuses | 2007 |
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Comprehensive Medicinal Chemistry II
E Littler, XX Zhou |
Comprehensive Medicinal Chemistry II | 2007 |
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High prevalence of malaria infection in Amazonas state, Venezuela
H Rodulfo, M Donato, I Quijada, A Peña |
Revista do Instituto de Medicina Tropical de São Paulo | 2007 |
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Design of New Plasmepsin Inhibitors: A Virtual High Throughput Screening Approach on the EGEE Grid
V Kasam, M Zimmermann, A Maaβ, H Schwichtenberg, A Wolf, N Jacq, V Breton, M Hofmann-Apitius |
Journal of Chemical Information and Modeling | 2007 |
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Infectious Diseases in Critical Care
J Rello, M Kollef, E Díaz, A Rodríguez |
2007 | |
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Bioactive Heterocycles III
MT Khan |
2007 | |
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Prevalence and Detection of Counterfeit Pharmaceuticals: A Mini Review
FM Fernandez, MD Green, PN Newton |
Industrial & engineering chemistry research | 2007 |
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Design and Synthesis of Potent Antimalarial Agents Based on Clotrimazole Scaffold: Exploring an Innovative Pharmacophore
S Gemma, G Campiani, S Butini, G Kukreja, BP Joshi, M Persico, B Catalanotti, E Novellino, E Fattorusso, V Nacci, L Savini, D Taramelli, N Basilico, G Morace, V Yardley, C Fattorusso |
Journal of Medicinal Chemistry | 2007 |
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In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos)
Mayfong Mayxay, Marion Barends, Alan Brockman, Anchalee Jaidee, Shalini Nair, Dan Sudimack, Tiengkham Pongvongsa, Samlane Phompida, Rattanaxay Phetsouvanh, Tim Anderson, Nicholas J White, Paul N Newton |
The American journal of tropical medicine and hygiene | 2007 |
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A study on antimalarial artemisinin derivatives using MEP maps and multivariate QSAR
FJ Cardoso, AF de Figueiredo, M da Silva Lobato, RM de Miranda, RC de Almeida, JC Pinheiro |
Journal of Molecular Modeling | 2007 |
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Infectious Disease and Therapy
A Tselis |
Epstein-Barr Virus | 2006 |
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Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease
SX Wang, KC Pandey, JR Somoza, PS Sijwali, T Kortemme, LS Brinen, RJ Fletterick, PJ Rosenthal, JH McKerrow |
Proceedings of the National Academy of Sciences | 2006 |
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Erythrocyte G protein as a novel target for malarial chemotherapy
SC Murphy, T Harrison, HE Hamm, JW Lomasney, N Mohandas, K Haldar |
PLoS Medicine | 2006 |
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Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum
SR Krungkrai, K Tokuoka, Y Kusakari, T Inoue, H Adachi, H Matsumura, K Takano, S Murakami, Y Mori, Y Kai, J Krungkrai, T Horii |
Acta crystallographica. Section F, Structural biology and crystallization communications | 2006 |
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Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance
S Krishna, CJ Woodrow, HM Staines, RK Haynes, O Mercereau-Puijalon |
Trends in Molecular Medicine | 2006 |
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Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malaria
WP O'Meara, DL Smith, FE McKenzie |
PLoS Medicine | 2006 |
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Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda
C Obua, M Ntale, MS Lundblad, M Mahindi, LL Gustafsson, JW Ogwal-Okeng, WW Anokbonggo, U Hellgren |
African health sciences | 2006 |
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Plasmepsins as potential targets for new antimalarial therapy
K Ersmark, B Samuelsson, A Hallberg |
Medicinal Research Reviews | 2006 |
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Malaria
GD Burchard |
Der Internist | 2006 |
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Resonance Raman spectroscopy in malaria research
BR Wood, D McNaughton |
Expert Review of Proteomics | 2006 |
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Using the genome to dissect the molecular basis of drug resistance
C Kidgell, EA Winzeler |
Future Microbiology | 2006 |
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Antimalarial drugs – host targets (re)visited
M Cunha-Rodrigues, M Prudêncio, MM Mota, W Haas |
Biotechnology Journal | 2006 |
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Production of the Artemisinin Precursor Amorpha-4,11-diene by Engineered Saccharomyces cerevisiae
AL Lindahl, ME Olsson, P Mercke, Ö Tollbom, J Schelin, M Brodelius, PE Brodelius |
Biotechnology Letters | 2006 |
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Plasmodium falciparum: Biochemical characterization of the cysteine protease falcipain-2′
N Singh, PS Sijwali, KC Pandey, PJ Rosenthal |
Experimental Parasitology | 2006 |
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The World Bank: false financial and statistical accounts and medical malpractice in malaria treatment
A Attaran, KI Barnes, R Bate, F Binka, U d'Alessandro, CI Fanello, L Garrett, TK Mutabingwa, D Roberts, CH Sibley, A Talisuna, JP geertruyden, WM Watkins |
The Lancet | 2006 |
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Problem pathogens: prevention of malaria in travellers
C Franco-Paredes, JI Santos-Preciado |
The Lancet Infectious Diseases | 2006 |
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Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains
S Gemma, G Kukreja, C Fattorusso, M Persico, MP Romano, M Altarelli, L Savini, G Campiani, E Fattorusso, N Basilico, D Taramelli, V Yardley, S Butini |
Bioorganic & Medicinal Chemistry Letters | 2006 |
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Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV
K Ersmark, M Nervall, H Gutiérrez-de-Terán, E Hamelink, LK Janka, JC Clemente, BM Dunn, A Gogoll, B Samuelsson, J Åqvist, A Hallberg |
Bioorganic & Medicinal Chemistry | 2006 |
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Molecular characterization and localization of Plasmodium falciparum choline kinase
V Choubey, M Guha, P Maity, S Kumar, R Raghunandan, PR Maulik, K Mitra, UC Halder, U Bandyopadhyay |
Biochimica et Biophysica Acta (BBA) - General Subjects | 2006 |
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Transporters involved in resistance to antimalarial drugs
SG Valderramos, DA Fidock |
Trends in Pharmacological Sciences | 2006 |
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Human cerebral malaria and the blood–brain barrier
IM Medana, GD Turner |
International Journal for Parasitology | 2006 |
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Efficacy and safety of the six-dose regimen of artemether–lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in adolescents and adults: A pooled analysis of individual patient data from randomized clinical trials
EA Mueller, M Vugt, W Kirch, K Andriano, P Hunt, PI de Palacios |
Acta Tropica | 2006 |
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Effect of antimalarial drugs on the bioavailability of the methylenediphosphonic acid labeled with technetium99m (99mTc-MDP) in Wistar rats
CM de Holanda, RC Leite, RA da Nunes, HA de Oliveira, MT de Catanho, GM de Souza, M Bernardo-Filho |
Brazilian Archives of Biology and Technology | 2006 |
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Mutations in the pfmdr1, cg2, and pfcrt genes in Plasmodium falciparum samples from endemic malaria areas in Rondonia and Pará State, Brazilian Amazon Region
GM Viana, RL Machado, VS Calvosa, MM Póvoa |
CAD SAUDE PUBLICA | 2006 |
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Characterization of Human Urinary Metabolites of the Antimalarial Piperaquine
J Tarning, Y Bergqvist, NP Day, J Bergquist, B Arvidsson, NJ White, M Ashton, N Lindegårdh |
Drug Metabolism and Disposition | 2006 |
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Should New Antimalarial Drugs Be Subsidized?
R Laxminarayan, IW Parry, DL Smith, E Klein |
SSRN Electronic Journal | 2006 |
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Endoperoxide Derivatives from Marine Organisms: 1,2-Dioxanes of the Plakortin Family as Novel Antimalarial Agents
C Fattorusso, G Campiani, B Catalanotti, M Persico, N Basilico, S Parapini, D Taramelli, C Campagnuolo, E Fattorusso, A Romano, O Taglialatela-Scafati |
Journal of Medicinal Chemistry | 2006 |
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High Antiplasmodial Activity of Novel Plasmepsins I and II Inhibitors
M Dell'Agli, S Parapini, G Galli, N Vaiana, D Taramelli, A Sparatore, P Liu, BM Dunn, E Bosisio, S Romeo |
Journal of Medicinal Chemistry | 2006 |
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Solution Structures of Conformationally Equilibrium Forms of Holo-Acyl Carrier Protein (PfACP) from Plasmodium falciparum Provides Insight into the Mechanism of Activation of ACPs ,
AK Sharma, SK Sharma, A Surolia, N Surolia, SP Sarma |
Biochemistry | 2006 |
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Thematic review series: Lipid Posttranslational Modifications. Fighting parasitic disease by blocking protein farnesylation
RT Eastman, FS Buckner, K Yokoyama, MH Gelb, WC Voorhis |
Journal of lipid research | 2006 |
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Dynamics of Gene Introgression in the African Malaria Vector Anopheles gambiae
D Zhong, EA Temu, T Guda, L Gouagna, D Menge, A Pai, J Githure, JC Beier, G Yan |
Genetics | 2006 |
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A Systematic Map of Genetic Variation in Plasmodium falciparum
C Kidgell, SK Volkman, J Daily, JO Borevitz, D Plouffe, Y Zhou, JR Johnson, KG Roch, O Sarr, O Ndir, S Mboup, S Batalov, DF Wirth, EA Winzeler, K Haldar |
PLoS pathogens | 2006 |
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The plastid-derived organelle ofprotozoan human parasites asa target of established and emerging drugs
J Wiesner, F Seeber |
Expert Opinion on Therapeutic Targets | 2005 |
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The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif
KC Pandey, SX Wang, PS Sijwali, AL Lau, JH McKerrow, PJ Rosenthal |
Proceedings of the National Academy of Sciences | 2005 |
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Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Senegal
D Ndiaye, JP Daily, O Sarr, O Ndir, O Gaye, S Mboup, DF Wirth |
Tropical medicine & international health : TM & IH | 2005 |
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Rolling back a malaria epidemic in South Africa
PE Duffy, TK Mutabingwa |
PLoS Medicine | 2005 |
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Drug-resistant malaria
JE Hyde |
Trends in Parasitology | 2005 |
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Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda
A Yeka, K Banek, N Bakyaita, SG Staedke, MR Kamya, A Talisuna, F Kironde, SL Nsobya, A Kilian, M Slater, A Reingold, PJ Rosenthal, F Wabwire-Mangen, G Dorsey |
PLoS Medicine | 2005 |
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Artemisinins
CJ Woodrow, RK Haynes, S Krishna |
Postgraduate medical journal | 2005 |
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Intermittent presumptive treatment for malaria
NJ White |
PLoS Medicine | 2005 |
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Plasmodium (Haemamoeba) cathemerium gene sequences for phylogenetic analysis of malaria parasites
SC Wiersch, WA Maier, H Kampen |
Parasitology Research | 2005 |
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Antimalarial Polyketide Cycloperoxides from the Marine SpongePlakortis simplex
C Campagnuolo, E Fattorusso, A Romano, O Taglialatela-Scafati, N Basilico, S Parapini, D Taramelli |
European Journal of Organic Chemistry | 2005 |
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MOLECULAR MECHANISMS OF RESISTANCE IN ANTIMALARIAL CHEMOTHERAPY: The Unmet Challenge
R Arav-Boger, TA Shapiro |
Annual Review of Pharmacology and Toxicology | 2005 |
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How do patients use antimalarial drugs? A review of the evidence
S Yeung, NJ White |
Tropical Medicine and International Health | 2005 |
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Drug Resistance Hampers Our Capacity to Roll Back Malaria
P Olliaro |
Clinical Infectious Diseases | 2005 |
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Design, Synthesis and Antimalarial Activity of Trifluoromethylartemisinin-Mefloquine Dual Molecules
F Grellepois, P Grellier, D Bonnet-Delpon, JP Bégué |
ChemBioChem | 2005 |
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Public-private partnership: from there to here
SL Croft |
Transactions of the Royal Society of Tropical Medicine and Hygiene | 2005 |
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Population biology and antimalarial resistance: The transmission of antimalarial drug resistance in Plasmodium falciparum
KI Barnes, NJ White |
Acta Tropica | 2005 |
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Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro
ST Mariga, JP Gil, WH Wernsdorfer, A Björkman |
Acta Tropica | 2005 |
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Evaluation of the Inhibitory Activities of the Extracts of Indonesian Traditional Medicinal Plants against Plasmodium falciparum and Babesia gibsoni
T MURNIGSIH, Subeki, H MATSUURA, K TAKAHASHI, M YAMASAKI, O YAMATO, Y MAEDE, K KATAKURA, M SUZUKI, S KOBAYASHI, Chairul, T YOSHIHARA |
Journal of Veterinary Medical Science | 2005 |
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Lewis acid catalysed rearrangements of unsaturated bicyclic [2.2.n] endoperoxides in the presence of vinyl silanes; access to novel Fenozan BO-7 analogues
PM O’Neill, SL Rawe, RC Storr, SA Ward, GH Posner |
Tetrahedron Letters | 2005 |
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Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor
O Burk, KA Arnold, AK Nussler, E Schaeffeler, E Efimova, BA Avery, MA Avery, MF Fromm, M Eichelbaum |
Molecular pharmacology | 2005 |
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Molecular Approaches to Malaria
IW Sherman |
2005 | |
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A Novel Enzyme Complex of Orotate Phosphoribosyltransferase and Orotidine 5‘-Monophosphate Decarboxylase in Human Malaria Parasite Plasmodiumfalciparum : Physical Association, Kinetics, and Inhibition Characterization ,
SR Krungkrai, BJ DelFraino, JA Smiley, P Prapunwattana, T Mitamura, T Horii, J Krungkrai |
Biochemistry | 2005 |
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Mono- and Bis-Thiazolium Salts Have Potent Antimalarial Activity
A Hamzé, E Rubi, P Arnal, M Boisbrun, C Carcel, X Salom-Roig, M Maynadier, S Wein, H Vial, M Calas |
Journal of Medicinal Chemistry | 2005 |
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Artemisinin‐based combination therapies for uncomplicated malaria
TM Davis, HA Karunajeewa, KF Ilett |
The Medical Journal of Australia | 2005 |
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In Vivo Evidence for the Specificity of Plasmodium falciparum Phosphoethanolamine Methyltransferase and Its Coupling to the Kennedy Pathway
G Pessi, JY Choi, JM Reynolds, DR Voelker, CB Mamoun |
The Journal of biological chemistry | 2005 |
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Resistance to a Protein Farnesyltransferase Inhibitor in Plasmodium falciparum
RT Eastman, J White, O Hucke, K Bauer, K Yokoyama, L Nallan, D Chakrabarti, CL Verlinde, MH Gelb, PK Rathod, WC Voorhis |
The Journal of biological chemistry | 2005 |
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Short-Course Regimens of Artesunate-Fosmidomycin in Treatment of Uncomplicated Plasmodium falciparum Malaria
S Borrmann, AA Adegnika, F Moussavou, S Oyakhirome, G Esser, PB Matsiegui, M Ramharter, I Lundgren, M Kombila, S Issifou, D Hutchinson, J Wiesner, H Jomaa, PG Kremsner |
Antimicrobial agents and chemotherapy | 2005 |
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Modern Malaria Chemoprophylaxis:
GD Shanks, MD Edstein |
Drugs | 2005 |
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Emerging infectious diseases
VR Racaniello |
Journal of Clinical Investigation | 2004 |
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Pharmacogenomic strategies against resistance development in microbial infections
W Ziebuhr, K Xiao, B Coulibaly, R Schwarz, T Dandekar |
Pharmacogenomics | 2004 |
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Apoptosis of human umbilical vein endothelial cells induced by artesunate
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Vascular Pharmacology | 2004 |
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Falciparum malaria: current therapeutic challenges:
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Current Opinion in Infectious Diseases | 2004 |
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Efficacy of sulfadoxine-pyrimethamine as first line treatment for malaria declining in Malawi
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Evidence-based Healthcare and Public Health | 2004 |
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Advances in Heterocyclic Chemistry
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