Mammals coexist in an overall symbiotic relationship with a complex array of commensal bacterial flora that colonizes the gastrointestinal tract. These intestinal bacteria interface with cells of the mucosal immune system, including DCs. Here we discuss mechanisms of interaction between intestinal bacteria and DCs and the role of localized gastrointestinal immune responses.
Holm H. Uhlig, Fiona Powrie
Title and authors | Publication | Year |
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Role of secretory IgA in the mucosal sensing of commensal bacteria.
Mathias A, Pais B, Favre L, Benyacoub J, Corthésy B |
Gut microbes | 2014 |
Intestinal alkaline phosphatase deficiency leads to lipopolysaccharide desensitization and faster weight gain.
Yang Y, Millán JL, Mecsas J, Guillemin K |
Infection and immunity | 2014 |