Obesity alters adipose tissue metabolic and endocrine function and leads to an increased release of fatty acids, hormones, and proinflammatory molecules that contribute to obesity associated complications. To further characterize the changes that occur in adipose tissue with increasing adiposity, we profiled transcript expression in perigonadal adipose tissue from groups of mice in which adiposity varied due to sex, diet, and the obesity-related mutations agouti (Ay) and obese (Lepob). We found that the expression of 1,304 transcripts correlated significantly with body mass. Of the 100 most significantly correlated genes, 30% encoded proteins that are characteristic of macrophages and are positively correlated with body mass. Immunohistochemical analysis of perigonadal, perirenal, mesenteric, and subcutaneous adipose tissue revealed that the percentage of cells expressing the macrophage marker F4/80 (F4/80+) was significantly and positively correlated with both adipocyte size and body mass. Similar relationships were found in human subcutaneous adipose tissue stained for the macrophage antigen CD68. Bone marrow transplant studies and quantitation of macrophage number in adipose tissue from macrophage-deficient (Csf1op/op) mice suggest that these F4/80+ cells are CSF-1 dependent, bone marrow–derived adipose tissue macrophages. Expression analysis of macrophage and nonmacrophage cell populations isolated from adipose tissue demonstrates that adipose tissue macrophages are responsible for almost all adipose tissue TNF-α expression and significant amounts of iNOS and IL-6 expression. Adipose tissue macrophage numbers increase in obesity and participate in inflammatory pathways that are activated in adipose tissues of obese individuals.
Stuart P. Weisberg, Daniel McCann, Manisha Desai, Michael Rosenbaum, Rudolph L. Leibel, Anthony W. Ferrante Jr.
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Kempf K, Röhling M, Banzer W, Braumann KM, Halle M, Schaller N, McCarthy D, Predel HG, Schenkenberger I, Tan S, Toplak H, Martin S, Berg A |
Nutrients | 2022 |
Slc7a8 Deletion Is Protective against Diet-Induced Obesity and Attenuates Lipid Accumulation in Multiple Organs.
Pitere RR, van Heerden MB, Pepper MS, Ambele MA |
Biology | 2022 |
The Preliminary Evaluation of Epigenetic Modifications Regulating the Expression of IL10 in Insulin-Resistant Adipocytes.
Cierzniak A, Kaliszewski K, Małodobra-Mazur M |
Genes & development | 2022 |
Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation.
Subash-Babu P, Mohammed Alowaidh H, Al-Harbi LN, Shamlan G, Aloud AA, AlSedairy SA, Alshatwi AA |
Molecules (Basel, Switzerland) | 2022 |
The Molecular Mechanisms of Intestinal Inflammation and Fibrosis in Crohn's Disease.
Hayashi Y, Nakase H |
Frontiers in physiology | 2022 |
Acetate-mediated-obestatin modulation attenuates adipose-hepatic dysmetabolism in high fat diet-induced obese rat model.
Olaniyi KS, Atuma CL, Sabinari IW, Mahmud H, Saidi AO, Fafure AA, Olatunji LA |
Endocrine | 2022 |
Sodium butyrate reduces endoplasmic reticulum stress by modulating CHOP and empowers favorable anti-inflammatory adipose tissue immune-metabolism in HFD fed mice model of obesity.
Kushwaha V, Rai P, Varshney S, Gupta S, Khandelwal N, Kumar D, Nilkanth Gaikwad A |
2022 | |
Current Insights Into the Role of Neuropeptide Y in Skin Physiology and Pathology.
Anderson ZT, Dawson AD, Slominski AT, Harris ML |
Frontiers in Endocrinology | 2022 |
Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding.
Müller C, Zidek LM, Eichwald S, Kortman G, Koster MH, Calkhoven CF |
eLife | 2022 |
Regulatory Roles of Caspase-11 Non-Canonical Inflammasome in Inflammatory Liver Diseases.
Yi YS |
International journal of molecular sciences | 2022 |
ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19.
El-Sayed Moustafa JS, Jackson AU, Brotman SM, Guan L, Villicaña S, Roberts AL, Zito A, Bonnycastle L, Erdos MR, Narisu N, Stringham HM, Welch R, Yan T, Lakka T, Parker S, Tuomilehto J, Seow J, Graham C, Huettner I, Acors S, Kouphou N, Wadge S, Duncan EL, Steves CJ, Doores KJ, Malim MH, Collins FS, Pajukanta P, Boehnke M, Koistinen HA, Laakso M, Falchi M, Bell JT, Scott LJ, Mohlke KL, Small KS |
International Journal of Obesity | 2022 |
The influence of gastric bypass surgery on the concentration of high mobility group box 1, nuclear factor erythroid 2-related factor 2 and the genes expression of high mobility group box 1, nuclear factor erythroid2-related factor 2, interleukin 6, and tumor necrosis factor-alpha in the peripheral blood mononuclear cells of patients with morbid obesity.
Khanaghaei M, Ziamajidi N, Poorolajal J, Asadikaram G, Nikoyan P, Bajian M, Abbasalipourkabir R |
Molecular Biology Reports | 2022 |
Dextran-Mimetic Quantum Dots for Multimodal Macrophage Imaging In Vivo, Ex Vivo, and In Situ.
Deng H, Konopka CJ, Prabhu S, Sarkar S, Medina NG, Fayyaz M, Arogundade OH, Vidana Gamage HE, Shahoei SH, Nall D, Youn Y, Dobrucka IT, Audu CO, Joshi A, Melvin WJ, Gallagher KA, Selvin PR, Nelson ER, Dobrucki LW, Swanson KS, Smith AM |
ACS Nano | 2022 |
Low density, high impact? Neutrophil changes in obesity and bariatric surgery
Roberts CF, Sheu EG |
EBioMedicine | 2022 |
Palmitic Acid and Oleic Acid Differently Modulate TLR2-Mediated Inflammatory Responses in Microglia and Macrophages
Howe AM, Burke S, O\u2019Reilly ME, McGillicuddy FC, Costello DA |
Molecular Neurobiology | 2022 |
Dual Relationship Between Stromal Cells and Immune Cells in the Tumor Microenvironment
Mun JY, Leem SH, Lee JH, Kim HS |
Frontiers in immunology | 2022 |
Extracellular Vesicles in Pathogenesis and Treatment of Metabolic Associated Fatty Liver Disease
Sun J, Zhang D, Li Y |
Frontiers in physiology | 2022 |
Inhaled or Ingested, Which Is Worse, E-Vaping or High-Fat Diet?
Chen H, Chan YL, Thorpe AE, Pollock CA, Saad S, Oliver BG |
Frontiers in immunology | 2022 |
Metabolic risk factors of ovarian cancer: a review.
Khanlarkhani N, Azizi E, Amidi F, Khodarahmian M, Salehi E, Pazhohan A, Farhood B, Mortezae K, Goradel NH, Nashtaei MS |
JBRA Assisted Reproduction | 2022 |
Brick by Brick: Building a Transdiagnostic Understanding of Inflammation in Psychiatry.
Thylur DS, Goldsmith DR |
Harvard Review of Psychiatry | 2022 |
The effects of phytochemicals and herbal bio-active compounds on tumour necrosis factor-α in overweight and obese individuals: a clinical review.
Bagherniya M, Mahdavi A, Abbasi E, Iranshahy M, Sathyapalan T, Sahebkar A |
InflammoPharmacology | 2022 |
A Straightforward Method for Adipocyte Size and Count Analysis Using Open-source Software QuPath.
Palomäki VA, Koivukangas V, Meriläinen S, Lehenkari P, Karttunen TJ |
Adipocyte | 2022 |
The Endocrine Adipose Organ: A System Playing a Central Role in COVID-19
Cinti F, Cinti S |
Cells | 2022 |
A Signature of Exaggerated Adipose Tissue Dysfunction in Type 2 Diabetes Is Linked to Low Plasma Adiponectin and Increased Transcriptional Activation of Proteasomal Degradation in Muscle
Sabaratnam R, Skov V, Paulsen SK, Juhl S, Kruse R, Hansen T, Halkier C, Kristensen JM, Vind BF, Richelsen B, Knudsen S, Dahlgaard J, Beck-Nielsen H, Kruse TA, Højlund K |
Cells | 2022 |
Insulin Resistance Promotes the Formation of Aortic Dissection by Inducing the Phenotypic Switch of Vascular Smooth Muscle Cells
Zheng H, Qiu Z, Chai T, He J, Zhang Y, Wang C, Ye J, Wu X, Li Y, Zhang L, Chen L |
Frontiers in Cardiovascular Medicine | 2022 |
Differential Effects of Exercise Programs on Neuregulin 4, Body Composition and Cardiometabolic Risk Factors in Men With Obesity
Saeidi A, Shishvan SR, Soltani M, Tarazi F, Doyle-Baker PK, Shahrbanian S, Mollabashi SS, Khosravi N, Laher I, Moriarty TA, Johnson KE, VanDusseldorp TA, Zouhal H |
Frontiers in physiology | 2022 |
Low-Grade Inflammation in the Pathogenesis of Osteoarthritis: Cellular and Molecular Mechanisms and Strategies for Future Therapeutic Intervention
Terkawi MA, Ebata T, Yokota S, Takahashi D, Endo T, Matsumae G, Shimizu T, Kadoya K, Iwasaki N |
Biomedicines | 2022 |
Integrated Omics Analysis Reveals Alterations in the Intestinal Microbiota and Metabolites of Piglets After Starvation
Ma Y, Lu C, Ji B, Qin J, Cai C, Yang Y, Zhao Y, Liang G, Guo X, Cao G, Li B, Gao P |
Frontiers in microbiology | 2022 |
ILC2s and Adipose Tissue Homeostasis: Progress to Date and the Road Ahead
Misawa T, Wagner M, Koyasu S |
Frontiers in immunology | 2022 |
Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice
Chen KY, De Angulo A, Guo X, More A, Ochsner SA, Lopez E, Saul D, Pang W, Sun Y, McKenna NJ, Tong Q |
2022 | |
Adipocyte differentiation between obese and lean conditions depends on changes in miRNA expression
Heo Y, Kim H, Lim J, Choi SS |
Scientific Reports | 2022 |
Effects of exercise and microbiota transplant on the memory of obesity-induced mice
Park SS, Kim SH, Kim CJ, Shin MS, Park YJ, Kim TW |
Journal of Exercise Rehabilitation | 2022 |
Regulation of Adipose Tissue Biology by Long-Chain Fatty Acids: Metabolic Effects and Molecular Mechanisms
Shin S |
Journal of Obesity & Metabolic Syndrome | 2022 |
Translating MSC Therapy in the Age of Obesity
Boland L, Bitterlich LM, Hogan AE, Ankrum JA, English K |
Frontiers in immunology | 2022 |
Obesity, Inflammation, and Immune System in Osteoarthritis
Nedunchezhiyan U, Varughese I, Sun AR, Wu X, Crawford R, Prasadam I |
Frontiers in immunology | 2022 |
Hepatic Insulin Resistance in Hyperthyroid Rat Liver: Vitamin E Supplementation Highlights a Possible Role of ROS
Fasciolo G, Napolitano G, Aprile M, Cataldi S, Costa V, Ciccodicola A, Di Meo S, Venditti P |
Antioxidants | 2022 |
Correlation of Body Mass Index and Proinflammatory Cytokine Levels with Hematopoietic Stem Cell Mobilization
Wang TF, Liou YS, Chang HH, Yang SH, Li CC, Wang JH, Sun DS |
Journal of Clinical Medicine | 2022 |
Neutrophil Elastase Increases Vascular Permeability and Leukocyte Transmigration in Cultured Endothelial Cells and Obese Mice
Ushakumari CJ, Zhou QL, Wang YH, Na S, Rigor MC, Zhou CY, Kroll MK, Lin BD, Jiang ZY |
Cells | 2022 |
Identification of key genes and their association with immune infiltration in adipose tissue of obese patients: a bioinformatic analysis
Wen J, Wang L |
Adipocyte | 2022 |
IFN-γ and LPS Induce Synergistic Expression of CCL2 in Monocytic Cells via H3K27 Acetylation
Akhter N, Kochumon S, Hasan A, Wilson A, Nizam R, Al Madhoun A, Al-Rashed F, Arefanian H, Alzaid F, Sindhu S, Al-Mulla F, Ahmad R |
Journal of inflammation research | 2022 |
From Obesity to Diabetes: The Role of the Adipose Organ.
Colleluori G, Perugini J, Giordano A, Cinti S |
Handbook of experimental pharmacology | 2022 |
Brown Adipose Tissue: A Short Historical Perspective.
Trayhurn P |
Methods in molecular biology (Clifton, N.J.) | 2022 |
Adipose Tissue Inflammation and Cardiovascular Disease: An Update.
Rana MN, Neeland IJ |
Current Diabetes Reports | 2022 |
A single-cell atlas of human and mouse white adipose tissue.
Emont MP, Jacobs C, Essene AL, Pant D, Tenen D, Colleluori G, Di Vincenzo A, Jørgensen AM, Dashti H, Stefek A, McGonagle E, Strobel S, Laber S, Agrawal S, Westcott GP, Kar A, Veregge ML, Gulko A, Srinivasan H, Kramer Z, De Filippis E, Merkel E, Ducie J, Boyd CG, Gourash W, Courcoulas A, Lin SJ, Lee BT, Morris D, Tobias A, Khera AV, Claussnitzer M, Pers TH, Giordano A, Ashenberg O, Regev A, Tsai LT, Rosen ED |
Nature | 2022 |
Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation.
Ren Y, Zhao H, Yin C, Lan X, Wu L, Du X, Griffiths HR, Gao D |
Frontiers in Endocrinology | 2022 |
White adipose tissue-derived factors and prostate cancer progression: mechanisms and targets for interventions.
Saha A, Hamilton-Reeves J, DiGiovanni J |
Cancer metastasis reviews | 2022 |
An Iron Refractory Phenotype in Obese Adipose Tissue Macrophages Leads to Adipocyte Iron Overload
Ameka MK, Beavers WN, Shaver CM, Ware LB, Kerchberger VE, Schoenfelt KQ, Sun L, Koyama T, Skaar EP, Becker L, Hasty AH |
International journal of molecular sciences | 2022 |
Fetuin-A in Activated Liver Macrophages Is a Key Feature of Non-Alcoholic Steatohepatitis.
Etienne Q, Lebrun V, Komuta M, Navez B, Thissen JP, Leclercq IA, Lanthier N |
Metabolites | 2022 |
Importance of the Microenvironment and Mechanosensing in Adipose Tissue Biology
Lecoutre S, Lambert M, Drygalski K, Dugail I, Maqdasy S, Hautefeuille M, Clément K |
Cells | 2022 |
Triglyceride-glucose index is prospectively associated with chronic kidney disease progression in Type 2 diabetes - mediation by pigment epithelium-derived factor.
Low S, Pek S, Moh A, Ang K, Khoo J, Shao YM, Tang WE, Lim Z, Subramaniam T, Sum CF, Lim SC |
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease | 2022 |
The adipocyte microenvironment and cancer.
Mukherjee A, Bilecz AJ, Lengyel E |
Cancer metastasis reviews | 2022 |
Autologous Human Immunocompetent White Adipose Tissue‐on‐Chip
Rogal J, Roosz J, Teufel C, Cipriano M, Xu R, Eisler W, Weiss M, Schenke\u2010Layland K, Loskill P |
Advanced Science | 2022 |
Panax notoginseng Saponin Protects Against Diabetic Cardiomyopathy Through Lipid Metabolism Modulation
Zhang C, Zhang B, Zhang X, Wang M, Sun X, Sun G |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2022 |
Metabolic Syndrome in Psoriasis Is Associated With Upregulation of CXCL16 on Monocytes and a Dysbalance in Innate Lymphoid Cells
Schielke L, Zimmermann N, Hobelsberger S, Steininger J, Strunk A, Blau K, Hernandez J, Künzel S, Ziegenbalg R, Rösing S, Beissert S, Abraham S, Günther C |
Frontiers in immunology | 2022 |
Visceral adiposity is associated with metabolic profiles predictive of type 2 diabetes and myocardial infarction
Raheem J, Sliz E, Shin J, Holmes MV, Pike GB, Richer L, Gaudet D, Paus T, Pausova Z |
2022 | |
Resveratrol pre-treatment alleviated caerulein-induced acute pancreatitis in high-fat diet-feeding mice via suppressing the NF-κB proinflammatory signaling and improving the gut microbiota
Zhang X, Yang G, Chen Y, Mu Z, Zhou H, Zhang L |
2022 | |
Early introduction of exercise prevents insulin resistance in postnatal overfed rats
Fischer SV, Appel MH, Naliwaiko K, Pagliosa DD, Araújo DN, Capote AE, Oliveira BA, Fernandes LC |
Brazilian Journal of Medical and Biological Research | 2022 |
Expression of adipokines and adipocytokines by epidural adipose tissue in cauda equina syndrome in dogs
Leisengang S, Gluding D, Hörster J, Peek V, Ott D, Rummel C, Schmidt MJ |
Journal of Veterinary Internal Medicine | 2022 |
Cutoff Points of Waist Circumference for Predicting Incident Non-Alcoholic Fatty Liver Disease in Middle-Aged and Older Korean Adults
Lee JH, Jeon S, Lee HS, Kwon YJ |
Nutrients | 2022 |
T-bet+ B cells accumulate in adipose tissue and exacerbate metabolic disorder during obesity
Hägglöf T, Vanz C, Kumagai A, Dudley E, Ortega V, Siller M, Parthasarathy R, Keegan J, Koenigs A, Shute T, Leadbetter EA |
Cell Metabolism | 2022 |
Obesity-Related Neuroinflammation: Magnetic Resonance and Microscopy Imaging of the Brain
Woo A, Botta A, Shi SS, Paus T, Pausova Z |
International journal of molecular sciences | 2022 |
Macrophages, Low-Grade Inflammation, Insulin Resistance and Hyperinsulinemia: A Mutual Ambiguous Relationship in the Development of Metabolic Diseases
Püschel GP, Klauder J, Henkel J |
Journal of Clinical Medicine | 2022 |
Endothelial Cell Insulin Signaling Regulates CXCR4 and Limits Leukocyte Adhesion to Endothelium
Rathjen T, Kunkemoeller B, Cederquist CT, Wang X, Lockhart SM, Patti JC, Willenbrock H, Olsen GS, Povlsen GK, Beck HC, Rasmussen LM, Li Q, Park K, King GL, Rask-Madsen C |
Arteriosclerosis, thrombosis, and vascular biology | 2022 |
A co-crystal berberine-ibuprofen improves obesity by inhibiting the protein kinases TBK1 and IKKɛ
Wang M, Xu R, Liu X, Zhang L, Qiu S, Lu Y, Zhang P, Yan M, Zhu J |
2022 | |
The purinergic signalling and inflammation in the pathogenesis and progression of diabetes: key factors and therapeutic targets.
de Lima AC, Chaves LM, Prestes SN, Mânica A, Cardoso AM |
Inflammation research : official journal of the European Histamine Research Society ... [et al.] | 2022 |
The obesity-breast cancer link: a multidisciplinary perspective.
Devericks EN, Carson MS, McCullough LE, Coleman MF, Hursting SD |
Cancer metastasis reviews | 2022 |
IL-25 directly modulates adipocyte function and inflammation through the regulation of adiponectin.
Jeerawattanawart S, Siripurkpong P, Roytrakul S, Angkasekwinai P |
Inflammation research : official journal of the European Histamine Research Society ... [et al.] | 2022 |
Placental diabesity: placental VEGF and CD31 expression according to pregestational BMI and gestational weight gain in women with gestational diabetes.
Sirico A, Rossi ED, Degennaro VA, Arena V, Rizzi A, Tartaglione L, Di Leo M, Pitocco D, Lanzone A |
Archives of Gynecology and Obstetrics | 2022 |
The role of obesity and bariatric surgery-induced weight loss in breast cancer.
Bohm MS, Sipe LM, Pye ME, Davis MJ, Pierre JF, Makowski L |
Cancer metastasis reviews | 2022 |
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling.
Chen JL, Feng ZL, Zhou F, Lou RH, Peng C, Ye Y, Lin LG |
Acta Pharmacologica Sinica | 2022 |
The dark side of Tregs during aging
Palatella M, Guillaume SM, Linterman MA, Huehn J |
Frontiers in immunology | 2022 |
Protective role of zinc in the pathogenesis of respiratory diseases
Luan R, Ding D, Xue Q, Li H, Wang Y, Yang J |
European Journal of Clinical Nutrition | 2022 |
Macrophage Polarization Mediated by Mitochondrial Dysfunction Induces Adipose Tissue Inflammation in Obesity
Xu L, Yan X, Zhao Y, Wang J, Liu B, Yu S, Fu J, Liu Y, Su J |
International journal of molecular sciences | 2022 |
Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption
Mackert O, Wirth EK, Sun R, Winkler J, Liu A, Renko K, Kunz S, Spranger J, Brachs S |
Molecular Metabolism | 2022 |
Adipose tissue regulatory T cells: differentiation and function.
Fooks AN, Beppu LY, Frias AB, D'Cruz LM |
International Reviews of Immunology | 2022 |
20 Years with SGBS cells - a versatile in vitro model of human adipocyte biology.
Tews D, Brenner RE, Siebert R, Debatin KM, Fischer-Posovszky P, Wabitsch M |
International Journal of Obesity | 2022 |
Altered adipose tissue macrophage populations in people with HIV on integrase inhibitor-containing antiretroviral therapy.
Vakili S, Paneru B, Guerrier CM, Miller J, Baumrin E, Forrestel A, Lynn K, Frank I, Lo Re V 3rd, Collman RG, Hill DA |
AIDS | 2022 |
Lipid Peroxidation in Obesity: Can Bariatric Surgery Help?
Soldo AM, Soldo I, Karačić A, Konjevod M, Perkovic MN, Glavan TM, Luksic M, Žarković N, Jaganjac M |
Antioxidants | 2022 |
Obesity: a perfect storm for carcinogenesis.
Harris BHL, Macaulay VM, Harris DA, Klenerman P, Karpe F, Lord SR, Harris AL, Buffa FM |
Cancer metastasis reviews | 2022 |
Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling.
Orliaguet L, Ejlalmanesh T, Humbert A, Ballaire R, Diedisheim M, Julla JB, Chokr D, Cuenco J, Michieletto J, Charbit J, Lindén D, Boucher J, Potier C, Hamimi A, Lemoine S, Blugeon C, Legoix P, Lameiras S, Baudrin LG, Baulande S, Soprani A, Castelli FA, Fenaille F, Riveline JP, Dalmas E, Rieusset J, Gautier JF, Venteclef N, Alzaid F |
Nature Communications | 2022 |
Adipocytes control food intake and weight regain via Vacuolar-type H+ ATPase.
Zapata RC, Carretero M, Reis FCG, Chaudry BS, Ofrecio J, Zhang D, Sasik R, Ciaraldi T, Petrascheck M, Osborn O |
Nature Communications | 2022 |
Food for thought - ILC metabolism in the context of helminth infections.
Michla M, Wilhelm C |
Mucosal Immunology | 2022 |
Anti-inflammatory agents as modulators of the inflammation in adipose tissue: A systematic review
da Cruz Nascimento SS, Carvalho de Queiroz JL, Fernandes de Medeiros A, de França Nunes AC, Piuvezam G, Lima Maciel BL, Souza Passos T, Morais AH |
PloS one | 2022 |
Remodeling of Adipose Tissues by Fatty Acids: Mechanistic Update on Browning and Thermogenesis by n-3 Polyunsaturated Fatty Acids.
Raj RR, Lofquist S, Lee MJ |
Pharmaceutical Research | 2022 |
Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2
Feng T, Zhao X, Gu P, Yang W, Wang C, Guo Q, Long Q, Liu Q, Cheng Y, Li J, Cheung CK, Wu D, Kong X, Xu Y, Ye D, Hua S, Loomes K, Xu A, Hui X |
Nature Communications | 2022 |
Analytical performance of a canine ELISA monocyte chemoattractant protein-1 assay for use in cats and evaluation of circulating levels in normal weight and obese cats
Stenberg K, Gensby L, Cremer SE, Nielsen MM, Bjørnvad CR |
Acta veterinaria Scandinavica | 2022 |
Adipose tissue macrophages in remote modulation of hepatic glucose production
Tao Y, Jiang Q, Wang Q |
Frontiers in immunology | 2022 |
Sex-specific effects of maternal weight loss on offspring cardiometabolic outcomes in the obese preeclamptic-like mouse model, BPH/5.
Beckers KF, Schulz CJ, Flanagan JP, Adams DM, Gomes VCL, Liu CC, Childers GW, Sones JL |
Physiological Reports | 2022 |
Breast cancer microenvironment and obesity: challenges for therapy.
Hillers-Ziemer LE, Kuziel G, Williams AE, Moore BN, Arendt LM |
Cancer metastasis reviews | 2022 |
Fibrosis in fat: From other diseases to Crohn's disease.
Xiong S, Tan J, Wang Y, He J, Hu F, Wu X, Liu Z, Lin S, Li X, Chen Z, Mao R |
Frontiers in immunology | 2022 |
Examination of the role of necroptotic damage-associated molecular patterns in tissue fibrosis.
Liu X, Lu F, Chen X |
Frontiers in immunology | 2022 |
Adipose tissue macrophage in obesity-associated metabolic diseases
Yao J, Wu D, Qiu Y |
Frontiers in immunology | 2022 |
The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging.
Ryu S, Sidorov S, Ravussin E, Artyomov M, Iwasaki A, Wang A, Dixit VD |
Immunity | 2022 |
A nexus of lipid and O-Glcnac metabolism in physiology and disease.
Lockridge A, Hanover JA |
Frontiers in Endocrinology | 2022 |
Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review.
Lv W, Xu D |
2022 | |
A modified standard American diet induces physiological parameters associated with metabolic syndrome in C57BL/6J mice.
Chehade SB, Green GBH, Graham CD, Chakraborti A, Vashai B, Moon A, Williams MB, Vickers B, Berryhill T, Van Der Pol W, Wilson L, Powell ML, Smith DL Jr, Barnes S, Morrow C, Mukhtar MS, Kennedy GD, Bibb JA, Watts SA |
Frontiers in Nutrition | 2022 |
Loss of myeloid lipoprotein lipase exacerbates adipose tissue fibrosis with collagen VI deposition and hyperlipidemia in leptin-deficient obese mice
Takahashi M, Yamamuro D, Wakabayashi T, Takei A, Takei S, Nagashima S, Okazaki H, Ebihara K, Yagyu H, Takayanagi Y, Onaka T, Goldberg IJ, Ishibashi S |
The Journal of biological chemistry | 2022 |
Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice
Patel S, Haider A, Alvarez-Guaita A, Bidault G, El-Sayed Moustafa JS, Guiu-Jurado E, Tadross JA, Warner J, Harrison J, Virtue S, Scurria F, Zvetkova I, Blüher M, Small KS, O\u2019Rahilly S, Savage DB |
Molecular Metabolism | 2022 |
The Role of Diet in Regulation of Macrophages Functioning
Varaeva YR, Kirichenko TV, Shaposhnikova NN, Nikityuk DB, Starodubova AV |
Biomedicines | 2022 |
The Adipose Organ Is a Unitary Structure in Mice and Humans
Giordano A, Cinti F, Canese R, Carpinelli G, Colleluori G, Di Vincenzo A, Palombelli G, Severi I, Moretti M, Redaelli C, Partridge J, Zingaretti MC, Agostini A, Sternardi F, Giovagnoni A, Castorina S, Cinti S |
Biomedicines | 2022 |
Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue–islet interactions
Oquendo MB, Lorza-Gil E, Juarez-Lopez D, Wagner R, Birkenfeld AL, Ullrich S, Gerst F |
Scientific Reports | 2022 |
Effects of Vitamin D Supplementation on Adipose Tissue Inflammation and NF-κB/AMPK Activation in Obese Mice Fed a High-Fat Diet
Chang E |
International journal of molecular sciences | 2022 |
Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesity.
Bradley D, Smith AJ, Blaszczak A, Shantaram D, Bergin SM, Jalilvand A, Wright V, Wyne KL, Dewal RS, Baer LA, Wright KR, Stanford KI, Needleman B, Brethauer S, Noria S, Renton D, Joseph JJ, Lovett-Racke A, Liu J, Hsueh WA |
Nature Communications | 2022 |
Immune Cell Activation in Obesity and Cardiovascular Disease
Garcia JN, Wanjalla CN, Mashayekhi M, Hasty AH |
Current Hypertension Reports | 2022 |
Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
Boroumand P, Prescott DC, Mukherjee T, Bilan PJ, Wong M, Shen J, Tattoli I, Zhou Y, Li A, Sivasubramaniyam T, Shi N, Zhu LY, Liu Z, Robbins C, Philpott DJ, Girardin SE, Klip A |
eLife | 2022 |
The Role of Prunes in Modulating Inflammatory Pathways to Improve Bone Health in Postmenopausal Women
Damani JJ, De Souza MJ, VanEvery HL, Strock NC, Rogers CJ |
Advances in Nutrition | 2022 |
Comparison of perinephric fat measurements between malignant and benign renal tumours
Tsai JP, Lin DC, Huang WM, Chen M, Chen YH |
2022 | |
Reciprocal signaling between adipose tissue depots and the central nervous system
Puente-Ruiz SC, Jais A |
Frontiers in Cell and Developmental Biology | 2022 |
Macrophages, Chronic Inflammation, and Insulin Resistance
Li H, Meng Y, He S, Tan X, Zhang Y, Zhang X, Wang L, Zheng W |
Cells | 2022 |
Aconitate decarboxylase 1 regulates glucose homeostasis and obesity in mice
Frieler RA, Vigil TM, Song J, Leung C, Goldstein DR, Lumeng CN, Mortensen RM |
Obesity (Silver Spring, Md.) | 2022 |
Modeling Obesity-Driven Pancreatic Carcinogenesis—A Review of Current In Vivo and In Vitro Models of Obesity and Pancreatic Carcinogenesis
Kfoury S, Michl P, Roth L |
Cells | 2022 |
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice.
Song Z, Liu N, He Y, Chen J, Li J, Wang F, Wu Z |
Inflammation | 2022 |
REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation.
Lee DK, Kim T, Byeon J, Park M, Kim S, Kim J, Choi S, Lee G, Park C, Lee KW, Kwon YJ, Lee JH, Kwon YG, Kim YM |
Nature Communications | 2022 |
The gut microbiota: a double-edged sword in endometriosis†.
Talwar C, Singh V, Kommagani R |
Biology of reproduction | 2022 |
Estradiol treatment increases M2-like visceral adipose tissue macrophages in obese ovariectomized mice regardless of its anorectic action.
Kim KD, Choe JM, Myoung S, Lee SH, Kim M, Choi JH, Park HT |
Animal Cells and Systems | 2022 |
Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity.
Ruggiero AD, Vemuri R, Block M, DeStephanis D, Davis M, Chou J, Williams A, Brock A, Das SK, Kavanagh K |
International journal of molecular sciences | 2022 |
Obesity-Related Cross-Talk between Prostate Cancer and Peripheral Fat: Potential Role of Exosomes.
Feng S, Lou K, Luo C, Zou J, Zou X, Zhang G |
Cancers | 2022 |
Netrin-1 Promotes Visceral Adipose Tissue Inflammation in Obesity and Is Associated with Insulin Resistance.
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Nutrients | 2022 |
Palmitoleic Acid Acts on Adipose-Derived Stromal Cells and Promotes Anti-Hypertrophic and Anti-Inflammatory Effects in Obese Mice.
Simão JJ, Cruz MM, Abdala FM, Bolsoni-Lopes A, Armelin-Correa L, Alonso-Vale MIC |
Pharmaceuticals (Basel, Switzerland) | 2022 |
TSH-SPP1/TRβ-TSH positive feedback loop mediates fat deposition of hepatocyte: Crosstalk between thyroid and liver.
Huang B, Wen W, Ye S |
Frontiers in immunology | 2022 |
Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations.
Joffin N, Gliniak CM, Funcke JB, Paschoal VA, Crewe C, Chen S, Gordillo R, Kusminski CM, Oh DY, Geldenhuys WJ, Scherer PE |
Nature metabolism | 2022 |
Skin, Liver, and Kidney Interactions Contribute to Skin Dryness in Aging KK-Ay/Tajcl Mice.
Hiramoto K, Goto K, Tanaka S, Horikawa T, Ooi K |
Biomedicines | 2022 |
Comprehensive analysis of epigenomics and transcriptome data to identify potential target genes associated with obesity.
Wu P, Guo L, Li X, Du Y, Lin X, Ma X, Lin Y, Wen C, Yang C, Liu N, Feng Q, Xue Y, Guan M |
Frontiers in Genetics | 2022 |
Single-nuclei analysis reveals depot-specific transcriptional heterogeneity and depot-specific cell types in adipose tissue of dairy cows.
Michelotti TC, Kisby BR, Flores LS, Tegeler AP, Fokar M, Crasto C, Menarim BC, Loux SC, Strieder-Barboza C |
Frontiers in Cell and Developmental Biology | 2022 |
Serum plays an important role in reprogramming the seasonal transcriptional profile of brown bear adipocytes.
Saxton MW, Perry BW, Evans Hutzenbiler BD, Trojahn S, Gee A, Brown AP, Merrihew GE, Park J, Cornejo OE, MacCoss MJ, Robbins CT, Jansen HT, Kelley JL |
iScience | 2022 |
Obesity: A Doorway to a Molecular Path Leading to Infertility.
Ahmad R, Haque M |
Cureus | 2022 |
UCP2 KO mice exhibit ameliorated obesity and inflammation induced by high-fat diet feeding
Kim DH, Kim HJ, Seong JK |
BMB Reports | 2022 |
Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity
Mathur N, Severinsen MC, Jensen ME, Naver L, Schrölkamp M, Laye MJ, Watt MJ, Nielsen S, Krogh-Madsen R, Pedersen BK, Scheele C |
Frontiers in Cell and Developmental Biology | 2022 |
The critical role of gut microbiota in obesity
Cheng Z, Zhang L, Yang L, Chu H |
Frontiers in Endocrinology | 2022 |
A soy-yoghurt-honey product as a therapeutic functional food: mode of action and narrative review
Berg A, McCarthy HD |
Heliyon | 2022 |
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2022 | |
Leptin signaling in breast cancer and its crosstalk with peroxisome proliferator-activated receptors α and γ.
Dana N, Ferns GA, Nedaeinia R, Haghjooy Javanmard S |
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico | 2022 |
The Role of Crosstalk between Adipose Cells and Myocytes in the Pathogenesis of Sarcopenic Obesity in the Elderly
Zamboni M, Mazzali G, Brunelli A, Saatchi T, Urbani S, Giani A, Rossi AP, Zoico E, Fantin F |
Cells | 2022 |
Cross-Sectional Associations of Body Adiposity, Sedentary Behavior, and Physical Activity with Hemoglobin and White Blood Cell Count
Koivula T, Lempiäinen S, Laine S, Sjöros T, Vähä-Ypyä H, Garthwaite T, Löyttyniemi E, Sievänen H, Vasankari T, Knuuti J, Heinonen IH |
International journal of environmental research and public health | 2022 |
Oxidative stress and antioxidant imbalance in ovulation disorder in patients with polycystic ovary syndrome
Li W, Liu C, Yang Q, Zhou Y, Liu M, Shan H |
Frontiers in Nutrition | 2022 |
How Does Lifestyle Affect Hematopoiesis and the Bone Marrow Microenvironment?
Vanhie JJ, De Lisio M |
Toxicologic pathology | 2022 |
Respiratory issues in patients with multiple sclerosis as a risk factor during SARS-CoV-2 infection: a potential role for exercise.
Razi O, Teixeira AM, Tartibian B, Zamani N, Knechtle B |
Molecular and Cellular Biochemistry | 2022 |
LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation.
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eLife | 2022 |
Extracellular vesicles biogenesis, isolation, manipulation and genetic engineering for potential in vitro and in vivo therapeutics: An overview.
Hadizadeh N, Bagheri D, Shamsara M, Hamblin MR, Farmany A, Xu M, Liang Z, Razi F, Hashemi E |
Frontiers in Bioengineering and Biotechnology | 2022 |
Circadian Disruption and Consequences on Innate Immunity and Inflammatory Response
Jerigova V, Zeman M, Okuliarova M |
International journal of molecular sciences | 2022 |
Differential Gene Expression of Subcutaneous Adipose Tissue among Lean, Obese, and after RYGB (Different Timepoints): Systematic Review and Analysis
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Nutrients | 2022 |
Impact of Dysfunctional Adipose Tissue Depots on the Cardiovascular System
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International journal of molecular sciences | 2022 |
Rapid Drop in Coronary Heart Disease Mortality in Czech Male Population—What Was Actually behind It?
Poledne R, Kralova A, Bartuskova H, Paukner K, Kauerova S, Fronek J, Lanska V, Kralova Lesna I |
Biomedicines | 2022 |
Multiple sclerosis and obesity: The role of adipokines
Correale J, Marrodan M |
Frontiers in immunology | 2022 |
Adipose tissue macrophages: Regulators of adipose tissue immunometabolism during obesity
Nance SA, Muir L, Lumeng C |
Molecular Metabolism | 2022 |
In vivo corneal confocal microscopy as a non-invasive test to assess obesity induced small fibre nerve damage and inflammation.
Gulkas S, Aydin FO, Turhan SA, Toker AE |
Eye | 2022 |
Immune response to arbovirus infection in obesity.
Hameed M, Geerling E, Pinto AK, Miraj I, Weger-Lucarelli J |
Frontiers in immunology | 2022 |
Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells
Afrin S, El Sabah M, Manzoor A, Miyashita-Ishiwata M, Reschke L, Borahay MA |
2022 | |
Ferroptosis increases obesity: Crosstalk between adipocytes and the neuroimmune system
Zhang S, Sun Z, Jiang X, Lu Z, Ding L, Li C, Tian X, Wang Q |
Frontiers in immunology | 2022 |
Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise
Komori T, Morikawa Y |
The Journal of biological chemistry | 2022 |
A low carbohydrate diet high in fish oil and soy protein delays inflammation, hematopoietic stem cell depletion, and mortality in miR-146a knock-out mice
Elisia I, Kowalski S, Yeung M, Wong J, Grants JM, Karsan A, Krystal G |
Frontiers in Nutrition | 2022 |
Mangiferin Ameliorates Obesity-Associated Inflammation and Autophagy in High-Fat-Diet-Fed Mice: In Silico and In Vivo Approaches
Noh JW, Lee HY, Lee BC |
International journal of molecular sciences | 2022 |
Ramulus Mori (Sangzhi) Alkaloids Ameliorate Obesity-Linked Adipose Tissue Metabolism and Inflammation in Mice
Sun QW, Lian CF, Chen YM, Ye J, Chen W, Gao Y, Wang HL, Gao LL, Liu YL, Yang YF |
Nutrients | 2022 |
The Role of Adipokines in Inflammatory Mechanisms of Obesity
Kirichenko TV, Markina YV, Bogatyreva AI, Tolstik TV, Varaeva YR, Starodubova AV |
International journal of molecular sciences | 2022 |
The PI3K/Akt Pathway in Meta-Inflammation
Acosta-Martinez M, Cabail MZ |
International journal of molecular sciences | 2022 |
Developmental endothelial locus-1 in cardiovascular and metabolic diseases: A promising biomarker and therapeutic target
Zhao M, Zheng Z, Li C, Wan J, Wang M |
Frontiers in immunology | 2022 |
The rheumatoid arthritis drug auranofin lowers leptin levels and exerts anti-diabetic effects in obese mice
Cox AR, Masschelin PM, Saha PK, Felix JB, Sharp R, Lian Z, Xia Y, Chernis N, Bader DA, Kim KH, Li X, Yoshino J, Li X, Li G, Sun Z, Wu H, Coarfa C, Moore DD, Klein S, Sun K, Hartig SM |
Cell Metabolism | 2022 |
MicroRNAs: a crossroad that connects obesity to immunity and aging
Rakib A, Kiran S, Mandal M, Singh UP |
Immunity & ageing : I & A | 2022 |
PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes
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Science Immunology | 2022 |
Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration
Mikkelsen RB, Arora T, Trošt K, Dmytriyeva O, Jensen SK, Meijnikman AS, Olofsson LE, Lappa D, Aydin Ö, Nielsen J, Gerdes V, Moritz T, van de Laar A, de Brauw M, Nieuwdorp M, Hjorth SA, Schwartz TW, Bäckhed F |
iScience | 2022 |
Metabolic syndrome and aberrant immune responses to viral infection and vaccination: Insights from small animal models
Geerling E, Hameed M, Weger-Lucarelli J, Pinto AK |
Frontiers in immunology | 2022 |
Creeping fat formation and interaction with intestinal disease in Crohn's disease
Yin Y, Xie Y, Ge W, Li Y |
United European gastroenterology journal | 2022 |
Time-restricted feeding reduces monocyte production by controlling hematopoietic stem and progenitor cells in the bone marrow during obesity
Kim Y, Lee Y, Lee MN, Nah J, Yun N, Wu D, Pae M |
Frontiers in immunology | 2022 |
Supplementing Diets with Agriophyllum squarrosum Reduced Blood Lipids, Enhanced Immunity and Anti-Inflammatory Capacities, and Mediated Lipid Metabolism in Tan Lambs.
Jiao D, Liang Y, Zhou S, Wu X, Degen AA, Hickford J, Zhou H, Cong H, Shi X, Ma X, Yang G |
2022 | |
Mannose Receptor Deficiency Impacts Bone Marrow and Circulating Immune Cells during High Fat Diet Induced Obesity.
Nour J, Moregola A, Svecla M, Da Dalt L, Bellini R, Neyrolles O, Fadini GP, Rombouts Y, Albiero M, Bonacina F, Norata GD |
Metabolites | 2022 |
Macrophage-Conditioned Media Promotes Adipocyte Cancer Association, Which in Turn Stimulates Breast Cancer Proliferation and Migration
Vallega KA, Bosco DB, Ren Y, Sang QX |
Biomolecules | 2022 |
Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity
Kochumon S, Arefanian H, Sindhu S, Thomas R, Jacob T, Al-Sayyar A, Shenouda S, Al-Rashed F, Koistinen HA, Al-Mulla F, Tuomilehto J, Ahmad R |
Cells | 2022 |
Obesity as a Risk Factor for Breast Cancer-The Role of miRNA.
Hanusek K, Karczmarski J, Litwiniuk A, Urbańska K, Ambrozkiewicz F, Kwiatkowski A, Martyńska L, Domańska A, Bik W, Paziewska A |
International journal of molecular sciences | 2022 |
Metabolic impact of adipose tissue macrophages in the early postnatal life
Röszer T |
Journal of leukocyte biology | 2022 |
Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-α-Stimulated Adipocytes
Zhang X, Gao Y, Liu Z, Li W, Kang Y, Li X, Xu Z, Peng C, Qi Y |
International journal of molecular sciences | 2022 |
Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status
Dance YW, Obenreder MC, Seibel AJ, Meshulam T, Ogony JW, Lahiri N, Pacheco-Spann L, Radisky DC, Layne MD, Farmer SR, Nelson CM, Tien J |
Cellular and Molecular Bioengineering | 2022 |
Development of a lactic acid bacteria strain that suppresses chronic inflammation and improves glucose and lipid metabolism
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Bioscience of Microbiota, Food and Health | 2022 |
Dysregulated systemic metabolism in a Down syndrome mouse model
Sarver DC, Xu C, Velez LM, Aja S, Jaffe AE, Seldin MM, Reeves RH, Wong GW |
Molecular Metabolism | 2022 |
The NLRP3 inflammasome activation in subcutaneous, epicardial and pericardial adipose tissue in patients with coronary heart disease undergoing coronary by-pass surgery.
Åkra S, Seljeflot I, Braathen B, Bratseth V, Hansen CH, Arnesen H, Tønnessen T, Solheim S |
2022 | |
TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling
Lee HH, Jeong GW, Ye BJ, Yoo EJ, Son KS, Kim DK, Park HK, Kang BH, Lee-Kwon W, Kwon HM, Choi SY |
Diabetes | 2022 |
Beneficial effects of intermittent fasting: a narrative review
Song DK, Kim YW |
2022 | |
Obesity aggravates contact hypersensitivity reaction in mice
Majewska-Szczepanik M, Kowalczyk P, Marcińska K, Strzępa A, Lis GJ, Susan Wong F, Szczepanik M, Wen L |
Contact Dermatitis | 2022 |
Obesity and Coronavirus Disease 2019
Fei S, Feng X, Luo J, Guo L, Pan Q |
Journal of Translational Internal Medicine | 2022 |
Pathologically triggered in situ aggregation of nanoparticles for inflammation-targeting amplification and therapeutic potentiation
Nie Q, Li C, Wang Y, Hu Y, Pu W, Zhang Q, Cai J, Lin Y, Li G, Wang C, Li L, Dou Y, Zhang J |
Acta pharmaceutica Sinica. B | 2022 |
Extracellular RNAs from immune cells under obesity—a narrative review
Karlinsey K, Matz A, Qu L, Zhou B |
2022 | |
DNA damage response signaling: A common link between cancer and cardiovascular diseases.
Nikfarjam S, Singh KK |
Cancer Medicine | 2022 |
Revisiting the role of IL-1 signaling in the development of apical periodontitis
Tazawa K, Azuma Presse MM, Furusho H, Stashenko P, Sasaki H |
2022 | |
In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
Huang K, Zapata D, Tang Y, Teng Y, Li Y |
Biomaterials | 2022 |
Functional Hallmarks of healthy Macrophage Responses: Their Regulatory Basis and Disease Relevance
Sheu K, Hoffmann A |
Annual Review of Immunology | 2022 |
Irisin reduces inflammatory signaling pathways in inflammation-mediated metabolic syndrome.
Slate-Romano JJ, Yano N, Zhao TC |
Molecular and Cellular Endocrinology | 2022 |
Metabolic strategy of macrophages under homeostasis or immune stress in Drosophila
Luo W, Liu S, Zhang F, Zhao L, Su Y |
2022 | |
Dynamics of adipose tissue macrophage populations after gastric bypass surgery
Palomäki VA, Lehenkari P, Meriläinen S, Karttunen TJ, Koivukangas V |
Obesity (Silver Spring, Md.) | 2022 |
One Week of Overeating Upregulates Angiogenic and Lipolytic Gene Expression in Human Subcutaneous Adipose Tissue from Exercise Trained and Untrained Adults
Ludzki AC, Krueger EM, Gillen JB, Taylor NM, Middlebrook DO, Baldwin TC, Karabetsos KC, Schleh MW, Horowitz JF |
2022 | |
Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity
Aaron N, Zahr T, He Y, Yu L, Mayfield B, Pajvani UB, Qiang L |
2022 | |
The Influence of Sex, Body Mass Index, and Age on Cellular and Humoral Immune Responses Against Measles After a Third Dose of Measles-Mumps-Rubella Vaccine
Quach HQ, Chen J, Monroe JM, Ratishvili T, Warner ND, Grill DE, Haralambieva IH, Ovsyannikova IG, Poland GA, Kennedy RB |
The Journal of Infectious Diseases | 2022 |
Cross-sectional study protocol to assess the environmental exposure of endocrine-disruptive chemicals: bisphenol A and heavy metals in children
Malik VS, Khaiwal R |
Pediatric endocrinology, diabetes, and metabolism | 2022 |
Inflammatory potential of diet and risk of mortality in normal-weight adults with central obesity
Choi MK, Mark Park YM, Shivappa N, Hong OK, Han K, Steck SE, Hébert JR, Merchant AT, Sandler DP, Lee SS |
Clinical nutrition (Edinburgh, Scotland) | 2022 |
Methanolic fruit extract of Myrica nagi protects the hypothalamus and attenuates inflammation associated with gold thioglucose- and high-fat diet-induced obesity via various adipokines
Prashar Y, Patel NJ |
Journal of Ayurveda and integrative medicine | 2022 |
Binge eating disorder, frequency of depression, and systemic inflammatory state in individuals with obesity – A cross sectional study
Caldas ND, Braulio VB, Brasil MA, Furtado VC, de Carvalho DP, Cotrik EM, Dantas JR, Zajdenverg L |
Archives of Endocrinology and Metabolism | 2022 |
The immunomodulatory functions of chromogranin A-derived peptide pancreastatin
Ioannidis M, Mahata SK, van den Bogaart G |
Peptides | 2022 |
Adipose tissue plasticity in health and disease
Sakers A, De Siqueira MK, Seale P, Villanueva CJ |
Cell | 2022 |
Psychological Stress During Childhood and Adolescence and Its Association With Inflammation Across the Lifespan: A Critical Review and Meta-Analysis.
Chiang JJ, Lam PH, Chen E, Miller GE |
Psychological bulletin | 2022 |
Impact of Conjugated Linoleic Acid on Obesity and Its Association with Macrophage Recruitment: Experimental and Immunohistochemical Study.
Abdou AG, Bendary MA, Abdou SE, Amer GS |
Journal of microscopy and ultrastructure | 2022 |
The Yin-Yang functions of macrophages in metabolic disorders
Bai J, Liu F |
Life Medicine | 2022 |
A novel strategy to dissect multifaceted macrophage function in human diseases
Karlinsey K, Qu L, Matz AJ, Zhou B |
Journal of leukocyte biology | 2022 |