Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice
Wouter J. de Jonge, … , Marinus C. Lamers, Wouter H. Lamers
Wouter J. de Jonge, … , Marinus C. Lamers, Wouter H. Lamers
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1539-1548. https://doi.org/10.1172/JCI16143.
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Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice

Abstract

Research Article

Authors

Wouter J. de Jonge, Karin L. Kwikkers, Anje A. te Velde, Sander J.H. van Deventer, Martijn A. Nolte, Reina E. Mebius, Jan M. Ruijter, Marinus C. Lamers, Wouter H. Lamers

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In vitro stimulation of proliferation of splenic B cells from wild-type ...
In vitro stimulation of proliferation of splenic B cells from wild-type and F/A-2+/+ mice. Splenic lymphocytes (105 cells per well) of 4-week-old mice were stimulated with LPS, goat F(ab′)2 anti-mouse μ chain, anti-CD40 antibody, or IL-4, either alone or in combination for 2 days (upper graph) or 3 days (lower graph). Cells of wild-type and F/A-2+/+ spleens displayed similar proliferative responses. Data are presented as mean of triplicate cultures.