Difference in sensitivity between SARS-CoV-2–specific T cell assays in patients with underlying conditions
Rory D. de Vries, … , Debbie van Baarle, RECOVAC-IR Collaborators
Rory D. de Vries, … , Debbie van Baarle, RECOVAC-IR Collaborators
Published December 15, 2021
Citation Information: J Clin Invest. 2021;131(24):e155499. https://doi.org/10.1172/JCI155499.
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Letter to the Editor Immunology Virology

Difference in sensitivity between SARS-CoV-2–specific T cell assays in patients with underlying conditions

Abstract

Authors

Rory D. de Vries, Marieke van der Heiden, Daryl Geers, Celine Imhof, Debbie van Baarle, RECOVAC-IR Collaborators

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Figure 1

Correlation between IFN-γ ELISpot and IGRA.

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Correlation between IFN-γ ELISpot and IGRA. Moderate correlation coeffic...
Moderate correlation coefficients (R) were observed between assays in both groups. The x axis shows IGRA results (IFN-γ) in international units (IU)/mL in serum; the y axis shows ELISpot results in spot-forming colonies (SFC)/106 PBMCs. Dotted lines indicate positive cutoffs.