Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus
David M. Koelle, Zhi Liu, Christopher M. McClurkan, Max S. Topp, Stanley R. Riddell, Eric G. Pamer, Andrew S. Johnson, Anna Wald, Lawrence Corey
David M. Koelle, Zhi Liu, Christopher M. McClurkan, Max S. Topp, Stanley R. Riddell, Eric G. Pamer, Andrew S. Johnson, Anna Wald, Lawrence Corey
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Article Immunology

Expression of cutaneous lymphocyte-associated antigen by CD8+ T cells specific for a skin-tropic virus

Abstract

Research Article

Authors

David M. Koelle, Zhi Liu, Christopher M. McClurkan, Max S. Topp, Stanley R. Riddell, Eric G. Pamer, Andrew S. Johnson, Anna Wald, Lawrence Corey

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Expression of cell-surface antigens by circulating HSV-2–specific CD8+ T...
Expression of cell-surface antigens by circulating HSV-2–specific CD8+ T cells. (a) PBMCs from donor 4196 were gated for lymphocyte size and scatter, high CD8α expression, and binding of tetramer B7-RPR, which is specific for VP22 a.a. 49–57. Expression of CD28, CD62L, and CCR7 is displayed in the indicated histograms. (b) Similar data for CD8α-high lymphocytes, which did not bind tetramer B7-RPR, from the same donor.