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Semaphorins as signals for cell repulsion and invasion
Yoshio Goshima, … , Yukio Sasaki, Fumio Nakamura
Yoshio Goshima, … , Yukio Sasaki, Fumio Nakamura
Published April 15, 2002
Citation Information: J Clin Invest. 2002;109(8):993-998. https://doi.org/10.1172/JCI15467.
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Perspective

Semaphorins as signals for cell repulsion and invasion

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Abstract

Authors

Yoshio Goshima, Takaaki Ito, Yukio Sasaki, Fumio Nakamura

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Figure 3

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Model of semaphorin functions in lung development. Sema3A opposes the ef...
Model of semaphorin functions in lung development. Sema3A opposes the effects of Sema3C and Sema3F, which activate branching morphogenesis in this tissue. The expression of the semaphorins and their receptors is tightly regulated, both spatially and temporally. The expression levels of semaphorins, neuropilins, and plexins are indicated as follows: ++, high; +, moderate; (see details in Kogashima et al, ref. 29).

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