JCI - Citations to Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa.

Citations to this article

Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa.

A Heeckeren, … , P B Davis, T Ferkol

A Heeckeren, … , P B Davis, T Ferkol

Published December 1, 1997
Citation Information: J Clin Invest. 1997;100(11):2810-2815. https://doi.org/10.1172/JCI119828.

View: Text | PDF

Research Article

Total citations by year

Year:	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014	2013	2012	2011	2010	2009	2008	2007	2006	2005	2004	2003	2002	2001	2000	1999	1998	Total
Citations:	1	5	4	8	6	9	7	3	11	10	2	7	4	25	10	10	14	10	14	8	19	7	13	14	14	7	3	245

Citation information

Citations to this article (245)

Title and authors	Publication	Year
A chronic Pseudomonas aeruginosa mouse lung infection modeling the pathophysiology and inflammation of human cystic fibrosis Vaillancourt M, Aguilar D, Fernandes SE, Jorth PA	bioRxiv	2024
Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics Wood SJ, Kuzel TM, Shafikhani SH	Cells	2023
Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury Sahu SK, Ozantürk AN, Kulkarni DH, Ma L, Barve RA, Dannull L, Lu A, Starick M, McPhatter J, Garnica L, Sanfillipo-Burchman M, Kunen J, Wu X, Gelman AE, Brody SL, Atkinson JP, Kulkarni HS	Science Immunology	2023
Human Mesenchymal Stem Cell (hMSC) Donor Potency Selection for the "First in Cystic Fibrosis" Phase I Clinical Trial (CEASE-CF). Bonfield TL, Sutton MT, Fletcher DR, Reese-Koc J, Roesch EA, Lazarus HM, Chmiel JF, Caplan AI	Pharmaceuticals (Basel, Switzerland)	2023
Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection. Wills BM, Garai P, Riegert MO, Sanchez FT, Pickrum AM, Frank DW, Brockman KL	Infection and immunity	2023
A minimally invasive bronchoscopic approach for direct delivery to murine airways and application to models of pulmonary infection. Schelde K, Rosenjack J, Sonneborn C, Jafri A, Kavran M, Brumbaugh S, Rietsch A, Darrah RJ, Hodges CA, Flask CA, Kelley TJ, Drumm ML	Laboratory Animals	2023
Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis C Pietro, H Öz, P Zhang, E Cheng, V Martis, T Bonfield, T Kelley, R Jubin, A Abuchowski, D Krause, M Egan, T Murray, E Bruscia	Experimental & molecular medicine	2022
COVID-19 in patients with chronic lung disease Calver JF, Fabbri L, May J, Jenkins RG	Clinics in Chest Medicine	2022
Mice with lung airway ciliopathy develop persistent Mycobacterium abscessus lung infection and have a proinflammatory lung phenotype associated with decreased T regulatory cells. Nava A, Hahn AC, Wu TH, Byrd TF	Frontiers in immunology	2022
Static mucus impairs bacterial clearance and allows chronic infection with Pseudomonas aeruginosa in the cystic fibrosis rat Henderson AG, Davis JM, Keith JD, Green ME, Oden AM, Rowe SM, Birket SE	European Respiratory Journal	2022
Rescue from Pseudomonas aeruginosa Airway Infection via Stem Cell Transplantation K Brinkert, S Hedtfeld, A Burhop, R Gastmeier, P Gad, D Wedekind, C Kloth, J Rothschuh, N Lachmann, M Hetzel, AC Jirmo, E Lopez-Rodriguez, C Brandenberger, G Hansen, A Schambach, M Ackermann, B Tümmler, A Munder	Molecular Therapy	2021
2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function M Wang, AG Gauthier, TP Kennedy, H Wang, UK Velagapudi, TT Talele, M Lin, J Wu, LA Daley, X Yang, V Patel, SS Mun, CR Ashby, LL Mantell	Molecular Medicine	2021
Enhancing Cystic Fibrosis Immune Regulation AM van Heeckeren, MT Sutton, DR Fletcher, CA Hodges, AI Caplan, TL Bonfield	Frontiers in pharmacology	2021
Analytical Methodologies for Biofilm Research M Nag, D Lahiri		2021
Environmental and clinical isolates of Herbaspirillum induce pulmonary infection in mice and its secretome is cytotoxic to human lung cells J Olszewski, CW Galvão, JJ Lipuma, KS Paludo	Journal of Medical Microbiology	2021
Donor‐defined mesenchymal stem cell antimicrobial potency against nontuberculous mycobacterium TL Bonfield, MT Sutton, DR Fletcher, MA Folz, V Ragavapuram, RA Somoza, AI Caplan	Stem Cells Translational Medicine	2021
The Interplay between the Unfolded Protein Response, Inflammation and Infection in Cystic Fibrosis P Trouvé, C Férec, E Génin	Cells	2021
Donor-defined mesenchymal stem cell antimicrobial potency against nontuberculous mycobacterium. Bonfield TL, Sutton MT, Fletcher DR, Folz MA, Ragavapuram V, Somoza RA, Caplan AI	Stem Cells Translational Medicine	2021
Lung immunoglobulin A immunity dysregulation in cystic fibrosis AM Collin, M Lecocq, S Noel, B Detry, FM Carlier, FA Nana, C Bouzin, T Leal, M Vermeersch, VD Rose, L Regard, C Martin, PR Burgel, D Hoton, S Verleden, A Froidure, C Pilette, S Gohy	EBioMedicine	2020
Airway Inflammation and Host Responses in the Era of CFTR Modulators K Keown, R Brown, DF Doherty, C Houston, MC McKelvey, S Creane, D Linden, DF McAuley, JC Kidney, S Weldon, DG Downey, CC Taggart	International journal of molecular sciences	2020
Dysregulated signalling pathways in innate immune cells with cystic fibrosis mutations S Lara-Reyna, J Holbrook, HH Jarosz-Griffiths, D Peckham, MF McDermott	Cellular and Molecular Life Sciences	2020
Progress in Model Systems of Cystic Fibrosis Mucosal Inflammation to Understand Aberrant Neutrophil Activity DR Laucirica, LW Garratt, A Kicic	Frontiers in immunology	2020
Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery B Siddhardha, M Dyavaiah, A Syed		2020
Review of Potential Pseudomonas Weaponry, Relevant to the Pseudomonas–Aspergillus Interplay, for the Mycology Community P Chatterjee, G Sass, W Swietnicki, DA Stevens	Journal of Fungi	2020
HDAC6 depletion improves cystic fibrosis mouse airway responses to bacterial challenge J Rosenjack, CA Hodges, RJ Darrah, TJ Kelley	Scientific Reports	2019
Animal Models in the Pathophysiology of Cystic Fibrosis A Semaniakou, RP Croll, V Chappe	Frontiers in pharmacology	2019
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis CR Esther, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, KA Ramsey, MR Markovetz, IC Garbarine, MG Forest, I Seim, B Zorn, CB Morrison, MF Delion, WR Thelin, D Villalon, JR Sabater, L Turkovic, S Ranganathan, SM Stick, RC Boucher	Science Translational Medicine	2019
Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications M Hill, M Twigg, EA Sheridan, JG Hardy, JS Elborn, CC Taggart, CJ Scott, ME Migaud	Pharmaceutics	2019
PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils L Yue, M Yan, ML Tremblay, TJ Lin, H Li, T Yang, X Song, T Xie, Z Xie, S Jeyaseelan	PloS one	2019
Helix Cracking Regulates the Critical Interaction between RetS and GacS in Pseudomonas aeruginosa JM Mancl, WK Ray, RF Helm, FD Schubot	Structure (London, England : 1993)	2019
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks S Hao, EA Roesch, A Perez, RL Weiner, LC Henderson, L Cummings, P Consiglio, J Pajka, A Eisenberg, L Yeh, CU Cotton, ML Drumm	Journal of Cystic Fibrosis	2019
31st International Symposium on Shock Waves 2: Applications A Sasoh, T Aoki, M Katayama		2019
Anti‐inflammatories and mucociliary clearance therapies in the age of CFTR modulators L Perrem, F Ratjen	Pediatric Pulmonology	2019
Mucus models to evaluate the diffusion of drugs and particles JY Lock, TL Carlson, RL Carrier	Advanced Drug Delivery Reviews	2018
Airway disease phenotypes in animal models of cystic fibrosis A McCarron, M Donnelley, D Parsons	Respiratory Research	2018
Animal and model systems for studying cystic fibrosis BH Rosen, M Chanson, LR Gawenis, J Liu, A Sofoluwe, A Zoso, JF Engelhardt	Journal of Cystic Fibrosis	2018
Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses FH Robledo-Avila, J de Dios Ruiz-Rosado, KL Brockman, BT Kopp, AO Amer, K McCoy, LO Bakaletz, S Partida-Sanchez	Journal of immunology (Baltimore, Md. : 1950)	2018
Long-term dietary (n-3) polyunsaturated fatty acids show benefits to the lungs of Cftr F508del mice C Portal, V Gouyer, R Léonard, MO Husson, F Gottrand, JL Desseyn, I Puebla	PloS one	2018
Hyperencapsulated mucoid pneumococcal isolates from patients with cystic fibrosis have increased biofilm density and persistence in vivo EA Dennis, MT Coats, S Griffin, B Pang, DE Briles, MJ Crain, WE Swords	Pathogens and Disease	2018
An Additive Manufacturing Approach that Enables the Field Deployment of Synthetic Biosensors D Wolozny, JR Lake, PG Movizzo, Z Long, WC Ruder	Engineering	2018
Genetic Modification of the Lung Directed Toward Treatment of Human Disease D Sondhi, KM Stiles, BP De, RG Crystal	Human Gene Therapy	2017
Effects of coconut oil on glycemia, inflammation, and urogenital microbial parameters in female Ossabaw mini-pigs AE Newell-Fugate, K Lenz, C Skenandore, RA Nowak, BA White, A Braundmeier-Fleming, A Gonzalez-Bulnes	PloS one	2017
Association of Antibiotics, Airway Microbiome, and Inflammation in Infants with Cystic Fibrosis JE Pittman, KM Wylie, K Akers, GA Storch, J Hatch, J Quante, KB Frayman, N Clarke, M Davis, SM Stick, GL Hall, G Montgomery, S Ranganathan, SD Davis, TW Ferkol	Annals of the American Thoracic Society	2017
Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus JA Bartlett, S Ramachandran, CL Wohlford-Lenane, CK Barker, AA Pezzulo, J Zabner, MJ Welsh, DK Meyerholz, DA Stoltz, PB McCray	American journal of respiratory and critical care medicine	2016
Protein Tyrosine Phosphatase-1B Negatively Impacts Host Defense against Pseudomonas aeruginosa Infection L Yue, Z Xie, H Li, Z Pang, RD Junkins, ML Tremblay, X Chen, TJ Lin	The American Journal of Pathology	2016
MicroRNA-322 inhibits inflammatory cytokine expression and promotes cell proliferation in LPS-stimulated murine macrophages by targeting NF-κB1 (p50) K Zhang, F Song, X Lu, W Chen, C Huang, L Li, D Liang, S Cao, H Dai	Bioscience Reports	2016
Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences GM Lavelle, MM White, N Browne, NG McElvaney, EP Reeves	BioMed Research International	2016
Epithelial Anion Transport as Modulator of Chemokine Signaling A Schnúr, P Hegyi, S Rousseau, GL Lukacs, G Veit	Mediators of Inflammation	2016
Interleukin-17 Pathophysiology and Therapeutic Intervention in Cystic Fibrosis Lung Infection and Inflammation D Hsu, P Taylor, D Fletcher, R Heeckeren, J Eastman, A Heeckeren, P Davis, JF Chmiel, E Pearlman, TL Bonfield, BA McCormick	Infection and immunity	2016
Targeted CFTR gene disruption with zinc-finger nucleases in human intestinal epithelial cells induces oxidative stress and inflammation ML Kleme, AT Sané, C Garofalo, E Levy	The International Journal of Biochemistry & Cell Biology	2016
Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections C Cigana, NI Lorè, C Riva, ID Fino, L Spagnuolo, B Sipione, G Rossi, A Nonis, G Cabrini, A Bragonzi	Scientific Reports	2016
Antimicrobial Properties of Mesenchymal Stem Cells: Therapeutic Potential for Cystic Fibrosis Infection, and Treatment MT Sutton, D Fletcher, SK Ghosh, A Weinberg, R Heeckeren, S Kaur, Z Sadeghi, A Hijaz, J Reese, HM Lazarus, DP Lennon, AI Caplan, TL Bonfield	Stem Cells International	2016
Increased susceptibility of cftr-/- mice to LPS-induced lung remodeling E Bruscia, PX Zhang, C Barone, B Scholte, RJ Homer, D Krause, ME Egan	American journal of physiology. Lung cellular and molecular physiology	2016
Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis K Liu, X Zhang, JT Zhang, LL Tsang, X Jiang, HC Chan	Oncotarget	2016
Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation P Zhang, J Cheng, S Zou, AD D'Souza, JL Koff, J Lu, PJ Lee, DS Krause, ME Egan, EM Bruscia	Nature Communications	2015
Inflammation and its genesis in cystic fibrosis: Inflammation in Cystic Fibrosis DP Nichols, JF Chmiel	Pediatric Pulmonology	2015
Mycobacterium abscessus Morphotype Comparison in a Murine Model LJ Caverly, SM Caceres, C Fratelli, C Happoldt, KM Kidwell, KC Malcolm, JA Nick, DP Nichols, N Palaniyar	PloS one	2015
The challenges of developing effective anti-inflammatory agents in cystic fibrosis SD Sagel	Journal of Cystic Fibrosis	2015
Dynamically Regulated CFTR Expression and Its Functional Role in Cutaneous Wound Healing: CFTR IN CUTANEOUS WOUND HEALING J Dong, X Jiang, X Zhang, KS Liu, J Zhang, J Chen, MK Yu, LL Tsang, YW Chung, Y Wang, W Zhou, HC Chan	Journal of Cellular Physiology	2015
Successful treatment of biofilm infections using shock waves combined with antibiotic therapy DP Gnanadhas, M Elango, S Janardhanraj, CS Srinandan, A Datey, RA Strugnell, J Gopalan, D Chakravortty	Scientific Reports	2015
Chronic lung infection by Pseudomonas aeruginosa biofilm is cured by L-Methionine in combination with antibiotic therapy DP Gnanadhas, M Elango, A Datey, D Chakravortty	Scientific Reports	2015
The Effects of CFTR and Mucoid Phenotype on Susceptibility and Innate Immune Responses in a Mouse Model of Pneumococcal Lung Disease EA Dennis, MT Coats, SE Griffin, JY Hale, L Novak, DE Briles, MJ Crain, B Beall	PloS one	2015
Changes in airway inflammation during pulmonary exacerbations in patients with cystic fibrosis and primary ciliary dyskinesia F Ratjen, V Waters, M Klingel, N McDonald, S Dell, TR Leahy, Y Yau, H Grasemann	The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology	2015
Metabolism and Bacterial Pathogenesis T Conway, P Cohen	Metabolism and Bacterial Pathogenesis	2015
Mechanisms of phagocytosis and host clearance of Pseudomonas aeruginosa RR Lovewell, YR Patankar, B Berwin	American journal of physiology. Lung cellular and molecular physiology	2014
Pseudomonas JL Ramos, JB Goldberg, A Filloux		2014
Hyperglycemia impedes lung bacterial clearance in a murine model of cystic fibrosis-related diabetes WR Hunt, SM Zughaier, DE Guentert, MA Shenep, M Koval, NA McCarty, JM Hansen	American journal of physiology. Lung cellular and molecular physiology	2013
Nebulized thiocyanate improves lung infection outcomes in mice JD Chandler, E Min, J Huang, DP Nichols, BJ Day	British Journal of Pharmacology	2013
Emery and Rimoin's Principles and Practice of Medical Genetics DC Wallace, MT Lott, V Procaccio	Emery and Rimoin's Principles and Practice of Medical Genetics	2013
Molecular Basis of Oxidative Stress: Chemistry, Mechanisms, and Disease Pathogenesis A Ramkissoon, AM Shapiro, MM Loniewska, PG Wells	Molecular Basis of Oxidative Stress: Chemistry, Mechanisms, and Disease Pathogenesis	2013
Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator PX Zhang, TS Murray, VR Villella, E Ferrari, S Esposito, A D'Souza, V Raia, L Maiuri, DS Krause, ME Egan, EM Bruscia	Journal of immunology (Baltimore, Md. : 1950)	2013
Ceramide in cystic fibrosis RM Ziobro, BD Henry, AB Lentsch, MJ Edwards, J Riethmüller, E Gulbins	Clinical Lipidology	2013
Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications M Cohen-Cymberknoh, E Kerem, T Ferkol, A Elizur	Thorax	2013
Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells AG Ziady, A Sokolow, S Shank, D Corey, R Myers, S Plafker, TJ Kelley	American journal of physiology. Lung cellular and molecular physiology	2012
Prevention of lung injury by Muc1 mucin in a mouse model of repetitive Pseudomonas aeruginosa infection T Umehara, K Kato, YS Park, EP Lillehoj, H Kawauchi, KC Kim	Inflammation Research	2012
CFTR negatively regulates cyclooxygenase-2-PGE2 positive feedback loop in inflammation J Chen, XH Jiang, H Chen, JH Guo, LL Tsang, MK Yu, WM Xu, HC Chan	Journal of Cellular Physiology	2012
Nonimmediate β-lactam reactions in patients with cystic fibrosis: P Whitaker, D Naisbitt, D Peckham	Current Opinion in Allergy and Clinical Immunology	2012
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Cystic Fibrosis MD Amaral, K Kunzelmann	Cystic Fibrosis	2011
Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation H Labenski, S Hedtfeld, T Becker, B Tümmler, F Stanke	European Journal of Human Genetics	2011
Effect of Polarized Release of CXC-Chemokines from Wild-Type and Cystic Fibrosis Murine Airway Epithelial Cells MM Farberman, A Ibricevic, TD Joseph, KT Akers, R Garcia-Medina, S Crosby, LL Clarke, SL Brody, TW Ferkol	American journal of respiratory cell and molecular biology	2011
Bronchial brushings for investigating airway inflammation and remodelling K Looi, EN Sutanto, B Banerjee, L Garratt, KM Ling, CJ Foo, SM Stick, A Kicic	Respirology	2011
Characterisation of a refined rat model of respiratory infection with Pseudomonas aeruginosa and the effect of ciprofloxacin EJ Growcott, A Coulthard, R Amison, EL Hardaker, V Saxena, L Malt, P Jones, A Grevot, C Poll, C Osborne, KH Banner	Journal of Cystic Fibrosis	2011
Autophagy JA Haspel, AM Choi	American journal of respiratory and critical care medicine	2011
Innate Inflammatory Responses of Pediatric Cystic Fibrosis Airway Epithelial Cells: Effects of Nonviral and Viral Stimulation EN Sutanto, A Kicic, CJ Foo, PT Stevens, D Mullane, DA Knight, SM Stick	American journal of respiratory cell and molecular biology	2011
Endotoxins: Structure, Function and Recognition X Wang, PJ Quinn		2010
Endotoxins: Structure, Function and Recognition X Wang, PJ Quinn		2010
Endotoxins: Structure, Function and Recognition X Wang, PJ Quinn		2010
Endotoxins: Structure, Function and Recognition X Wang, PJ Quinn		2010
Endotoxins: Structure, Function and Recognition X Wang, PJ Quinn		2010
Endotoxins: Structure, Function and Recognition X Wang, PJ Quinn		2010
IL-10 delivery by AAV5 vector attenuates inflammation in mice with pseudomonas pneumonia SM Buff, H Yu, JN McCall, SM Caldwell, TW Ferkol, TR Flotte, IL Virella-Lowell	Gene Therapy	2010
Potential of anti-inflammatory treatment for cystic fibrosis lung disease JL Taylor-Cousar, KA von Kessel, R Young, DP Nichols	Journal of inflammation research	2010
AMPK Agonists Ameliorate Sodium and Fluid Transport and Inflammation in Cystic Fibrosis Airway Epithelial Cells MM Myerburg, JD King, NM Oyster, AC Fitch, A Magill, CJ Baty, SC Watkins, JK Kolls, JM Pilewski, KR Hallows	American journal of respiratory cell and molecular biology	2010
Pseudomonas aeruginosa Alginate Promotes Burkholderia cenocepacia Persistence in Cystic Fibrosis Transmembrane Conductance Regulator Knockout Mice SS Chattoraj, R Murthy, S Ganesan, JB Goldberg, Y Zhao, MB Hershenson, US Sajjan	Infection and immunity	2010
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells MM Myerburg, JD King, NM Oyster, AC Fitch, A Magill, CJ Baty, SC Watkins, JK Kolls, JM Pilewski, KR Hallows	American journal of respiratory cell and molecular biology	2009
Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences RW Vandivier, TR Richens, SA Horstmann, AM deCathelineau, M Ghosh, SD Reynolds, YQ Xiao, DW Riches, J Plumb, E Vachon, GP Downey, PM Henson	American journal of physiology. Lung cellular and molecular physiology	2009
In vitro and in vivo functional characterization of gutless recombinant SV40-derived CFTR vectors C Mueller, MS Strayer, J Sirninger, S Braag, F Branco, JP Louboutin, TR Flotte, DS Strayer	Gene Therapy	2009
CFTR is a negative regulator of NFkappaB mediated innate immune response N Vij, S Mazur, PL Zeitlin	PloS one	2009
Murine Model for Cystic Fibrosis Bone Disease Demonstrates Osteopenia and Sex-Related Differences in Bone Formation TD Pashuck, SE Franz, MK Altman, CH Wasserfall, MA Atkinson, TJ Wronski, TR Flotte, MS Stalvey	Pediatric Research	2009
Trichosanthin functions as Th2-type adjuvant in induction of allergic airway inflammation Y Wang, K Mao, S Sun, G Lin, X Wu, G Yao, B Sun	Cell Research	2009
How useful are cystic fibrosis mouse models? ME Egan	Drug Discovery Today: Disease Models	2009
Chloride channelopathies R Planells-Cases, TJ Jentsch	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease	2009
CFTR Is a Negative Regulator of NFκB Mediated Innate Immune Response N Vij, S Mazur, PL Zeitlin, D Hartl	PloS one	2009
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells. Myerburg MM, King JD Jr, Oyster NM, Fitch AC, Magill A, Baty CJ, Watkins SC, Kolls JK, Pilewski JM, Hallows KR	American journal of respiratory cell and molecular biology	2009
AAV Targeted Disruption of the CFTR Gene in Cloned Ferrets Xingshen Sun; Ziying Yan; Yaling Yi; Ziyi Li; Diana Lei; Christopher S. Rogers; Juan Chen; Michael J. Welsh; Gregory H. Leno; and John F. Engelhardt	Journal of Clinical Investigation	2008
cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells ME Manson, DA Corey, NM White, TJ Kelley	American journal of physiology. Lung cellular and molecular physiology	2008
α‐Toxin Facilitates the Generation of CXC Chemokine Gradients and Stimulates Neutrophil Homing in Staphylococcus aureus Pneumonia AH Bartlett, TJ Foster, A Hayashida, PW Park	The Journal of Infectious Diseases	2008
Macrophages directly contribute to the exaggerated inflammatory response in cystic fibrosis transmembrane conductance regulator-/- mice EM Bruscia, PX Zhang, E Ferreira, C Caputo, JW Emerson, D Tuck, DS Krause, ME Egan	American journal of respiratory cell and molecular biology	2008
Monitoring infection and inflammation in murine models of cystic fibrosis with magnetic resonance imaging VR Sheth, RC van Heeckeren, AG Wilson, AM van Heeckeren, MD Pagel	Journal of magnetic resonance imaging : JMRI	2008
Peroxisome proliferator-activated receptor-gamma in cystic fibrosis lung epithelium A Perez, AM van Heeckeren, D Nichols, S Gupta, JF Eastman, PB Davis	American journal of physiology. Lung cellular and molecular physiology	2008
CFTR mutations impart elevated immune reactivity in a murine model of cystic fibrosis related diabetes MS Stalvey, TM Brusko, C Mueller, CH Wasserfall, DA Schatz, MA Atkinson, TR Flotte	Cytokine	2008
Alterations in immune response and PPAR/LXR regulation in cystic fibrosis macrophages C Andersson, MM Zaman, AB Jones, SD Freedman	Journal of Cystic Fibrosis	2008
The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr−/−-dependent allergy mouse model C Mueller, SA Braag, AT Martino, Q Tang, M Campbell-Thompson, TR Flotte	Gene Therapy	2008
Airway Inflammation in Cystic Fibrosis A Elizur, CL Cannon, TW Ferkol	Chest	2008
Animal models of chronic lung infection with Pseudomonas aeruginosa : useful tools for cystic fibrosis studies I Kukavica-Ibrulj, RC Levesque	Laboratory Animals	2008
cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells ME Manson, DA Corey, NM White, TJ Kelley	American journal of physiology. Lung cellular and molecular physiology	2008
Peroxisome proliferator-activated receptor-γ in cystic fibrosis lung epithelium A Perez, AM van Heeckeren, D Nichols, S Gupta, JF Eastman, PB Davis	American journal of physiology. Lung cellular and molecular physiology	2008
TLR2 Regulates Gap Junction Intercellular Communication in Airway Cells FJ Martin, AS Prince	Journal of immunology (Baltimore, Md. : 1950)	2008
Chronic Inflammation in the Cystic Fibrosis Lung: Alterations in Inter- and Intracellular Signaling D Nichols, J Chmiel, M Berger	Clinical Reviews in Allergy & Immunology	2007
What have we learned from mouse models for cystic fibrosis? I Carvalho-Oliveira, BJ Scholte, D Penque	Expert Review of Molecular Diagnostics	2007
Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa D Tetaert, M Pierre, D Demeyer, MO Husson, L Béghin, C Galabert, F Gottrand, C Beermann, B Guery, JL Desseyn	Respiratory Research	2007
Pathogenesis of Bronchiectasis BM Morrissey	Clinics in Chest Medicine	2007
Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene C Mueller, D Torrez, S Braag, A Martino, T Clarke, M Campbell-Thompson, TR Flotte	The Journal of Gene Medicine	2007
Cystic Fibrosis Mouse Models C Guilbault, Z Saeed, GP Downey, D Radzioch	American journal of respiratory cell and molecular biology	2007
Effects of cystic fibrosis transmembrane conductance regulator and ΔF508CFTR on inflammatory response, ER stress, and Ca 2+ of airway epithelia K Hybiske, Z Fu, C Schwarzer, J Tseng, J Do, N Huang, TE Machen	American journal of physiology. Lung cellular and molecular physiology	2007
A role for CFTR in the elevation of glutathione levels in the lung by oral glutathione administration C Kariya, H Leitner, E Min, C van Heeckeren, A van Heeckeren, BJ Day	American journal of physiology. Lung cellular and molecular physiology	2007
Resistance of the antibacterial agent ceragenin CSA-13 to inactivation by DNA or F-actin and its activity in cystic fibrosis sputum R Bucki, AG Sostarecz, FJ Byfield, PB Savage, PA Janmey	Journal of Antimicrobial Chemotherapy	2007
A Role of Toll-IL-1 Receptor Domain-Containing Adaptor-Inducing IFN-β in the Host Response to Pseudomonas aeruginosa Lung Infection in Mice MR Power, B Li, M Yamamoto, S Akira, TJ Lin	Journal of immunology (Baltimore, Md. : 1950)	2007
Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice C Müller, SA Braag, JD Herlihy, CH Wasserfall, SE Chesrown, HS Nick, MA Atkinson, TR Flotte	Laboratory Investigation	2006
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection AD Gregory, LA Hogue, TW Ferkol, DC Link	Blood	2006
Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator S Tirkos, S Newbigging, V Nguyen, M Keet, C Ackerley, G Kent, RF Rozmahel	Respiratory Research	2006
Antioxidants in cystic fibrosis. Conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003 AM Cantin, TB White, CE Cross, HJ Forman, RJ Sokol, D Borowitz	Free radical biology & medicine	2006
Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice LW Velsor, C Kariya, R Kachadourian, BJ Day	American journal of respiratory cell and molecular biology	2006
Advances in cystic fibrosis therapies SM Rowe, JP Clancy	Current Opinion in Pediatrics	2006
Dysregulated interleukin-8 secretion and NF-κB activity in human cystic fibrosis nasal epithelial cells S Carrabino, D Carpani, A Livraghi, MD Cicco, D Costantini, E Copreni, C Colombo, M Conese	Journal of Cystic Fibrosis	2006
Chronic Pseudomonas aeruginosa infection reduces surfactant levels by inhibiting its biosynthesis Y Wu, Z Xu, FC Henderson, AJ Ryan, TL Yahr, RK Mallampalli	Cellular Microbiology	2006
Cystic Fibrosis Transmembrane Conductance Regulator Deficiency Exacerbates Islet Cell Dysfunction After -Cell Injury MS Stalvey, C Muller, DA Schatz, CH Wasserfall, ML Campbell-Thompson, DW Theriaque, TR Flotte, MA Atkinson	Diabetes	2006
Azithromycin reduces spontaneous and induced inflammation in ΔF508 cystic fibrosis mice R Legssyer, F Huaux, J Lebacq, M Delos, E Marbaix, P Lebecque, D Lison, BJ Scholte, P Wallemacq, T Leal	Respiratory Research	2006
Innate immune response in CF airway epithelia: hyperinflammatory? TE Machen	American journal of physiology. Cell physiology	2006
Adherence of airway neutrophils and inflammatory response are increased in CF airway epithelial cell-neutrophil interactions O Tabary, H Corvol, E Boncoeur, K Chadelat, C Fitting, JM Cavaillon, A Clément, J Jacquot	American journal of physiology. Lung cellular and molecular physiology	2006
Distinct pattern of lung gene expression in the Cftr -KO mice developing spontaneous lung disease compared with their littermate controls C Guilbault, JP Novak, P Martin, ML Boghdady, Z Saeed, MC Guiot, TJ Hudson, D Radzioch	Physiological genomics	2006
Principles of Molecular Medicine MS Runge, C Patterson		2006
Response to acute lung infection with mucoid Pseudomonas aeruginosa in cystic fibrosis mice AM van Heeckeren, MD Schluchter, W Xue, PB Davis	American journal of respiratory and critical care medicine	2005
Regulation of lung injury and repair by Toll-like receptors and hyaluronan D Jiang, J Liang, J Fan, S Yu, S Chen, Y Luo, GD Prestwich, MM Mascarenhas, HG Garg, DA Quinn, RJ Homer, DR Goldstein, R Bucala, PJ Lee, R Medzhitov, PW Noble	Nature Medicine	2005
Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis N Hoffmann, TB Rasmussen, PØ Jensen, C Stub, M Hentzer, S Molin, O Ciofu, M Givskov, HK Johansen, N Høiby	Infection and immunity	2005
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia RT Sadikot, TS Blackwell, JW Christman, AS Prince	American journal of respiratory and critical care medicine	2005
Progress towards gene therapy for cystic fibrosis S Tate, S Elborn	Expert Opinion on Drug Delivery	2005
Increased susceptibility of purinergic receptor-deficient mice to lung infection with Pseudomonasaeruginosa C Geary, H Akinbi, T Korfhagen, JE Fabre, R Boucher, W Rice	American journal of physiology. Lung cellular and molecular physiology	2005
NF-κB activation and sustained IL-8 gene expression in primary cultures of cystic fibrosis airway epithelial cells stimulated with Pseudomonas aeruginosa T Joseph, D Look, T Ferkol	American journal of physiology. Lung cellular and molecular physiology	2005
Computational Genetics and Genomics G Peltz		2005
TLR2 Is Mobilized Into An Apical Lipid Raft Receptor Complex To Signal Infection In Airway Epithelial Cells Grace Soong, Bharat Reddy, Sach Sokol, Robert Adamo, Alice Prince	Journal of Clinical Investigation	2004
Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered MM Zaman, A Gelrud, O Junaidi, MM Regan, M Warny, JC Shea, C Kelly, BP O'Sullivan, SD Freedman	Clinical and diagnostic laboratory immunology	2004
Some like it hot: curcumin and CFTR PB Davis, ML Drumm	Trends in Molecular Medicine	2004
Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1 MI Gómez, A Lee, B Reddy, A Muir, G Soong, A Pitt, A Cheung, A Prince	Nature Medicine	2004
Functional Characterization of a Recombinant Adeno- Associated Virus 5-Pseudotyped Cystic Fibrosis Transmembrane Conductance Regulator Vector J Sirninger, C Muller, S Braag, Q Tang, H Yue, C Detrisac, T Ferkol, WB Guggino, TR Flotte	Human Gene Therapy	2004
Pseudomonas aeruginosa-Induced Neutrophilic Lung Inflammation Is Attenuated by Adenovirus-Mediated Transfer of the Heme Oxygenase 1 cDNA in Mice T Tsuburai, T Kaneko, Y Nagashima, A Ueda, A Tagawa, T Shinohara, Y Ishigatsubo	Human Gene Therapy	2004
Airway epithelial cell–pathogen interactions A Bragonzi, E Copreni, S Bentzmann, M Ulrich, M Conese	Journal of Cystic Fibrosis	2004
Animal models of cystic fibrosis BJ Scholte, DJ Davidson, M Wilke, HR de Jonge	Journal of Cystic Fibrosis	2004
Toll-Like Receptors in Normal and Cystic Fibrosis Airway Epithelial Cells A Muir, G Soong, S Sokol, B Reddy, MI Gomez, A Heeckeren, A Prince	American journal of respiratory cell and molecular biology	2004
Preferential Diaphragmatic Weakness during Sustained Pseudomonas aeruginosa Lung Infection M Divangahi, S Matecki, RW Dudley, SA Tuck, W Bao, D Radzioch, AS Comtois, BJ Petrof	American journal of respiratory and critical care medicine	2004
Effects of CFTR, interleukin-10, and Pseudomonas aeruginosa on gene expression profiles in a CF bronchial epithelial cell Line I Virella-Lowell, JD Herlihy, B Liu, C Lopez, P Cruz, C Muller, HV Baker, TR Flotte	Molecular Therapy	2004
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice M Mall, BR Grubb, JR Harkema, WK O'Neal, RC Boucher	Nature Medicine	2004
Role of Cftr genotype in the response to chronic Pseudomonas aeruginosa lung infection in mice AM van Heeckeren, MD Schluchter, ML Drumm, PB Davis	American journal of physiology. Lung cellular and molecular physiology	2004
Effect of Pseudomonas-induced chronic lung inflammation on specific cytotoxic T-cell responses to adenoviral vectors in mice MF Tosi, A Heeckeren, TW Ferkol, D Askew, CV Harding, JM Kaplan	Gene Therapy	2004
Delivery of CFTR by adenoviral vector to cystic fibrosis mouse lung in a model of chronic Pseudomonas aeruginosa lung infection AM van Heeckeren, A Scaria, MD Schluchter, TW Ferkol, S Wadsworth, PB Davis	American journal of physiology. Lung cellular and molecular physiology	2004
Defects of Secretion in Cystic Fibrosis C Schultz		2004
Transfected β3- but Not β2-Adrenergic Receptors Regulate Cystic Fibrosis Transmembrane Conductance Regulator Activity via a New Pathway Involving the Mitogen-Activated Protein Kinases Extracellular Signal-Regulated Kinases A Robay, G Toumaniantz, V Leblais, C Gauthier	Molecular pharmacology	2004
Role for Cystic Fibrosis Transmembrane Conductance Regulator Protein in a Glutathione Response to Bronchopulmonary Pseudomonas Infection BJ Day, AM van Heeckeren, E Min, LW Velsor	Infection and immunity	2004
Nutritional Effects on Host Response to Lung Infections with Mucoid Pseudomonas aeruginosa in Mice AM van Heeckeren, M Schluchter, L Xue, J Alvarez, S Freedman, JS George, PB Davis	Infection and immunity	2004
Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection FT Coleman, S Mueschenborn, G Meluleni, C Ray, VJ Carey, SO Vargas, CL Cannon, FM Ausubel, GB Pier	Proceedings of the National Academy of Sciences	2003
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3 T Stein, JS Morris, CR Davies, SJ Weber-Hall, MA Duffy, VJ Heath, AK Bell, RK Ferrier, GP Sandilands, BA Gusterson	Breast Cancer Research	2003
Pulmonary edema fluid antioxidants are depressed in acute lung injury: RP Bowler, LW Velsor, B Duda, ED Chan, E Abraham, LB Ware, MA Matthay, BJ Day	Critical Care Medicine	2003
Minimal toxicity of stabilized compacted DNA nanoparticles in the murine lung AG Ziady, CR Gedeon, O Muhammad, V Stillwell, SM Oette, TL Fink, W Quan, TH Kowalczyk, SL Hyatt, J Payne, A Peischl, JE Seng, RC Moen, MJ Cooper, PB Davis	Molecular Therapy	2003
Chemokines in the Lung: Mechanisms and Consequences D Riches	Chemokines in the Lung: Mechanisms and Consequences	2003
Glycobiology and Medicine JS Axford		2003
The CepIR quorum-sensing system contributes to the virulence of Burkholderia cenocepacia respiratory infections PA Sokol, U Sajjan, MB Visser, S Gingues, J Forstner, C Kooi	Microbiology	2003
Characterization of LPS-induced lung inflammation in cftr-/- mice and the effect of docosahexaenoic acid SD Freedman, D Weinstein, PG Blanco, P Martinez-Clark, S Urman, M Zaman, JD Morrow, JG Alvarez	Journal of applied physiology	2002
The Role of Inflammation in the Pathophysiology of CF Lung Disease JF Chmiel, M Berger, MW Konstan	Clinical Reviews in Allergy & Immunology	2002
Correlation between an in vitro invasion assay and a murine model of Burkholderia cepacia lung infection MV Cieri, N Mayer-Hamblett, A Griffith, JL Burns	Infection and immunity	2002
Development of Population Pharmacokinetic Models and Optimal Sampling Times for Ibuprofen Tablet and Suspension Formulations in Children With Cystic Fibrosis P Beringer, A Aminimanizani, T Synold, C Scott	Therapeutic Drug Monitoring	2002
Cannabinoids and Cystic Fibrosis E Fride	Journal of Cannabis Therapeutics	2002
Bacterial Stimulation of Epithelial G-CSF and GM-CSF Expression Promotes PMN Survival in CF Airways S Saba, G Soong, S Greenberg, A Prince	American journal of respiratory cell and molecular biology	2002
Inflammatory Response in Airway Epithelial Cells Isolated from Patients with Cystic Fibrosis N Aldallal, EE McNaughton, LJ Manzel, AM Richards, J Zabner, TW Ferkol, DC Look	American journal of respiratory and critical care medicine	2002
Prolonged Inflammatory Response to Acute Pseudomonas Challenge in Interleukin-10 Knockout Mice JF Chmiel, MW Konstan, A Saadane, JE Krenicky, H Lester Kirchner, M Berger	American journal of respiratory and critical care medicine	2002
Lung Inflammation Early in Cystic Fibrosis: Bugs Are Indicted, But the Defense Is Guilty M Berger	American journal of respiratory and critical care medicine	2002
Matrilysin Shedding of Syndecan-1 Regulates Chemokine Mobilization and Transepithelial Efflux of Neutrophils in Acute Lung Injury Q Li, PW Park, CL Wilson, WC Parks	Cell	2002
Impairment of macrophage survival by NaCl: implications for early pulmonary inflammation in cystic fibrosis GS Kerby, V Cottin, FJ Accurso, F Hoffmann, ED Chan, VA Fadok, DW Riches	American journal of physiology. Lung cellular and molecular physiology	2002
Staphylococcus aureusagr and sarA Functions Are Required for Invasive Infection but Not Inflammatory Responses in the Lung G Heyer, S Saba, R Adamo, W Rush, G Soong, A Cheung, A Prince	Infection and immunity	2002
Functional IL-10 Deficiency in the Lung of Cystic Fibrosis ( cftr−/− ) and IL-10 Knockout Mice Causes Increased Expression and Function of B7 Costimulatory Molecules on Alveolar Macrophages J Soltys, T Bonfield, J Chmiel, M Berger	Journal of immunology (Baltimore, Md. : 1950)	2002
Nitric Oxide Deficiency Contributes to Impairment of Airway Relaxation in Cystic Fibrosis Mice MJ Mhanna, T Ferkol, RJ Martin, IA Dreshaj, AM van Heeckeren, TJ Kelley, MA Haxhiu	American journal of respiratory cell and molecular biology	2001
Mouse models of cystic fibrosis DJ Davidson, M Rolfe	Trends in Genetics	2001
Host–bacterial interactions in the initiation of inflammation D Rastogi, AJ Ratner, A Prince	Paediatric Respiratory Reviews	2001
Chinks in the Armor of the Airway: Pseudomonas Infection in the Cystic Fibrosis Lung TW Ferkol, DC Look	American journal of respiratory cell and molecular biology	2001
Cystic Fibrosis Pathogens Activate Ca 2+ -dependent Mitogen-activated Protein Kinase Signaling Pathways in Airway Epithelial Cells AJ Ratner, R Bryan, A Weber, S Nguyen, D Barnes, A Pitt, S Gelber, A Cheung, A Prince	The Journal of biological chemistry	2001
Activation of NF-κB in airway epithelial cells is dependent on CFTR trafficking and Cl − channel function AJ Weber, G Soong, R Bryan, S Saba, A Prince	American journal of physiology. Lung cellular and molecular physiology	2001
Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines D Kube, U Sontich, D Fletcher, PB Davis	American journal of physiology. Lung cellular and molecular physiology	2001
Tumor Necrosis Factor α Increases the Expression of Glycosyltransferases and Sulfotransferases Responsible for the Biosynthesis of Sialylated and/or Sulfated Lewis x Epitopes in the Human Bronchial Mucosa P Delmotte, S Degroote, JJ Lafitte, G Lamblin, JM Perini, P Roussel	The Journal of biological chemistry	2001
G551D CF mice display an abnormal host response and have impaired clearance of Pseudomonas lung disease BJ McMorran, JS Palmer, DP Lunn, D Oceandy, EO Costelloe, GR Thomas, DA Hume, BJ Wainwright	American journal of physiology. Lung cellular and molecular physiology	2001
Antioxidant imbalance in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice LW Velsor, A van Heeckeren, BJ Day	American journal of physiology. Lung cellular and molecular physiology	2001
Enhanced Susceptibility to Pulmonary Infection withBurkholderia cepacia inCftr−/− Mice EI Tuomanen, U Sajjan, G Thanassoulis, V Cherapanov, A Lu, C Sjolin, B Steer, YJ Wu, OD Rotstein, G Kent, C McKerlie, J Forstner, GP Downey	Infection and immunity	2001
Human airway mucin glycosylation: a combinatory of carbohydrate determinants which vary in cystic fibrosis G Lamblin, S Degroote, J M Perini, P Delmotte, A Scharfman, M Davril, J M Lo-Guidice, N Houdret, V Dumur, A Klein, P Rousse	Glycoconjugate Journal	2001
FAB-MS characterization of sialyl Lewis x determinants on polylactosamine chains of human airway mucins secreted by patients suffering from cystic fibrosis or chronic bronchitis W Morelle, M Sutton-Smith, H R Morris, M Davril, P Roussel, A Dell	Glycoconjugate Journal	2001
Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells. Stecenko AA, King G, Torii K, Breyer RM, Dworski R, Blackwell TS, Christman JW, Brigham KL	Inflammation	2001
In vivo alterations of interferon regulatory factor-1 and protein inhibitor of activated Stat-1 protein levels in cystic fibrosis epithelium Thomas J. Kelley, Heather L. Elmer	Journal of Clinical Investigation	2000
Enhanced epithelial gene transfer by modulation of tight junctions with sodium caprate CB Coyne, MM Kelly, RC Boucher, LG Johnson	American journal of respiratory cell and molecular biology	2000
Mouse models of chronic lung infection withPseudomonas Aeruginosa: Models for the study of cystic fibrosis PK Stotland, D Radzioch, MM Stevenson	Pediatric Pulmonology	2000
Cytokine dysregulation in activated cystic fibrosis (CF) peripheral lymphocytes RB Moss, YP Hsu, L Olds	Clinical & Experimental Immunology	2000
Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts S Mahajan-Miklos, LG Rahme, FM Ausubel	Molecular Microbiology	2000
MECHANISMS TO EXPLAIN PANCREATIC DYSFUNCTION IN CYSTIC FIBROSIS SD Freedman, P Blanco, JC Shea, JG Alvarez	Medical Clinics of North America	2000
Pseudomonas aeruginosa Induction of Apoptosis in Respiratory Epithelial Cells: Analysis of the Effects of Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction and Bacterial Virulence Factors S Rajan, G Cacalano, R Bryan, AJ Ratner, CU Sontich, A Heerckeren, P Davis, A Prince	American journal of respiratory cell and molecular biology	2000
Cystic Fibrosis Transmembrane Conductance Regulator–Dependent Regulation of Epithelial Inducible Nitric Oxide Synthase Expression WK Steagall, HL Elmer, KG Brady, TJ Kelley	American journal of respiratory cell and molecular biology	2000
Altered intracellular pH regulation in neutrophils from patients with cystic fibrosis RJ Coakley, C Taggart, G Canny, P Greally, SJ O'Neill, NG McElvaney	American journal of physiology. Lung cellular and molecular physiology	2000
G551D cystic fibrosis mice exhibit abnormal regulation of inflammation in lungs and macrophages GR Thomas, EA Costelloe, DP Lunn, KJ Stacey, SJ Delaney, R Passey, EC McGlinn, BJ McMorran, A Ahadizadeh, CL Geczy, BJ Wainwright, DA Hume	Journal of immunology (Baltimore, Md. : 1950)	2000
Effect of Pseudomonas Infection on Weight Loss, Lung Mechanics, and Cytokines in Mice AN van HEECKEREN, J Tscheikuna, RW Walenga, MW Konstan, PB Davis, B Erokwu, MA Haxhiu, TW Ferkol	American journal of respiratory and critical care medicine	2000
Role of Cystic Fibrosis Transmembrane Conductance Regulator in Pulmonary Clearance of Pseudomonas aeruginosa In Vivo ZC Chroneos, SE Wert, JL Livingston, DJ Hassett, JA Whitsett	Journal of immunology (Baltimore, Md. : 1950)	2000
Persistent Bacterial Infections JP Nataro, MJ Blaser, S Cunningham-Rundles		2000
CXC Chemokine Receptor CXCR2 Is Essential for Protective Innate Host Response in Murine Pseudomonas aeruginosa Pneumonia JD Clements, WC Tsai, RM Strieter, B Mehrad, MW Newstead, X Zeng, TJ Standiford	Infection and immunity	2000
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice SD Freedman, MH Katz, EM Parker, M Laposata, MY Urman, JG Alvarez	Proceedings of the National Academy of Sciences	1999
Inflammatory markers in cystic fibrosis patients with lung Pseudomonas aeruginosa infection AL Pukhalsky, NI Kapranov, EA Kalashnikova, GV Shmarina, LA Shabalova, SN Kokarovtseva, DA Pukhalskaya, NJ Kashirskaja, OI Simonova	Mediators of Inflammation	1999
The sialylation of bronchial mucins secreted by patients suffering from cystic fibrosis or from chronic bronchitis is related to the severity of airway infection M Davril, S Degroote, P Humbert, C Galabert, V Dumur, JJ Lafitte, G Lamblin, P Roussel	Glycobiology	1999
Pseudomonas aeruginosa binds to neoglycoconjugates bearing mucin carbohydrate determinants and predominantly to sialyl-Lewis x conjugates A Scharfman, S Degroote, J Beau, G Lamblin, P Roussel, J Mazurier	Glycobiology	1999
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr-/- mice SD Freedman, MH Katz, EM Parker, M Laposata, MY Urman, JG Alvarez	Proceedings of the National Academy of Sciences	1999
IL-10 Attenuates Excessive Inflammation in Chronic Pseudomonas Infection in Mice JF Chmiel, MW Konstan, JE Knesebeck, JB Hilliard, TL Bonfield, DV Dawson, M Berger	American journal of respiratory and critical care medicine	1999
Efficient killing of inhaled bacteria in ΔF508 mice: role of airway surface liquid composition PB McCray, J Zabner, HP Jia, MJ Welsh, PS Thorne	American journal of physiology. Lung cellular and molecular physiology	1999
Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells E DiMango, AJ Ratner, R Bryan, S Tabibi, A Prince	Journal of Clinical Investigation	1998
Selective Up-Regulation of Chemokine IL-8 Expression in Cystic Fibrosis Bronchial Gland Cells in Vivo and in Vitro O Tabary, JM Zahm, J Hinnrasky, JP Couetil, P Cornillet, M Guenounou, D Gaillard, E Puchelle, J Jacquot	The American Journal of Pathology	1998
Genetics and pulmonary medicine. 1. The genetics of cystic fibrosis lung disease DJ Davidson, DJ Porteous	Thorax	1998

Advertisement