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Citations to this article

Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha.
V Modur, … , S M Prescott, T M McIntyre
V Modur, … , S M Prescott, T M McIntyre
Published December 1, 1997
Citation Information: J Clin Invest. 1997;100(11):2752-2756. https://doi.org/10.1172/JCI119821.
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Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha.

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Research Article

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V Modur, Y Li, G A Zimmerman, S M Prescott, T M McIntyre

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A Bernardo, C Ball, L Nolasco, JF Moake, J Dong
Blood 2004
Soluble IL-6 receptor governs IL-6 activity in experimental arthritis: blockade of arthritis severity by soluble glycoprotein 130
MA Nowell, PJ Richards, S Horiuchi, N Yamamoto, S Rose-John, N Topley, AS Williams, SA Jones
Journal of immunology (Baltimore, Md. : 1950) 2003
Interleukins in Atherosclerosis: Molecular Pathways and Therapeutic Potential
JH der Thüsen, J Kuiper, TJ Berkel, EA Biessen
Pharmacological reviews 2003
Role of soluble gp130 in the tumour necrosis factor-alpha expression and its production by peripheral blood mononuclear cells
E Jablonskaca, W Puzewska, M Marcinczyk, J Jablonski
Mediators of Inflammation 2003
The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover
PK Wong, IK Campbell, PJ Egan, M Ernst, IP Wicks
Arthritis & Rheumatism 2003
The potential role of peroxisome proliferator–activated receptors on inflammation in type 2 diabetes mellitus and atherosclerosis
J Plutzky
The American Journal of Cardiology 2003
Interleukin-6-deficient mice resist development of autoimmune myocarditis associated with impaired upregulation of complement C3
U Eriksson, MO Kurrer, N Schmitz, SC Marsch, A Fontana, HP Eugster, M Kopf
Circulation 2003
Interleukin-11 and Interleukin-6 Protect Cultured Human Endothelial Cells from H 2 O 2 -Induced Cell Death
AB Waxman, K Mahboubi, RG Knickelbein, LL Mantell, N Manzo, JS Pober, JA Elias
American journal of respiratory cell and molecular biology 2003
Effect of soluble interleukin-6 receptor alpha and interleukin-6 secreted by polymorphonuclear leukocytes on tumor necrosis factor-alpha expression and its production by peripheral blood mononuclear cells
E Jablonska
Mediators of Inflammation 2002
Production of growth related oncogene protein-α in human umbilical vein endothelial cells stimulated with soluble interleukin-6 receptor-α: role of signal transducers, janus kinase 2 and mitogen-activated kinase kinase
T Matsumiya, T Imaizumi, H Itaya, T Shibata, H Yoshida, H Sakaki, H Kimura, K Satoh
Life Sciences 2002
Soluble Interleukin 6 Receptor (sIL-6R) Mediates Colonic Tumor Cell Adherence to the Vascular Endothelium: A Mechanism for Metastatic Initiation?
JF Dowdall, DC Winter, E Andrews, WE Laug, JH Wang, HP Redmond
Journal of Surgical Research 2002
The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex
D Aasland, B Oppmann, J Grötzinger, S Rose-John, KJ Kallen
Journal of Molecular Biology 2002
The role of soluble receptors in cytokine biology: the agonistic properties of the sIL-6R/IL-6 complex
SA Jones, S Rose-John
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2002
The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases
Karl-Josef Kallen
Biochimica et Biophysica Acta 2002
Endothelin Antagonism and Interleukin-6 Inhibition Attenuate the Proatherogenic Effects of C-Reactive Protein
S Verma, SH Li, MV Badiwala, RD Weisel, PW Fedak, RK Li, B Dhillon, DA Mickle
Circulation 2002
A Perinatal Strategy For Preventing Adult Disease: The Role Of Long-Chain Polyunsaturated Fatty Acids
UN Das
2002
Mediators of Acute Lung Injury: A Review
JM Sethi, AB Waxman
Clinical Pulmonary Medicine 2001
Is obesity an inflammatory condition?
UN Das
Nutrition 2001
IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation
SM Hurst, TS Wilkinson, RM McLoughlin, S Jones, S Horiuchi, N Yamamoto, S Rose-John, GM Fuller, N Topley, SA Jones
Immunity 2001
Soluble Interleukin-6 Receptor α Inhibits the Cytokine-Induced Fractalkine/CX3CL1 Expression in Human Vascular Endothelial Cells in Culture
T Matsumiya, T Imaizumi, K Fujimoto, X Cui, T Shibata, W Tamo, M Kumagai, K Tanji, H Yoshida, H Kimura, K Satoh
Experimental Cell Research 2001
SIGNALING THROUGH CD31 PROTECTS ENDOTHELIAL CELLS FROM APOPTOSIS:
PC Evans, ER Taylor, PJ Kilshaw
Transplantation 2001
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
SA Jones, S Horiuchi, N Topley, N Yamamoto, GM Fuller
The FASEB Journal 2001
Physiology of Inflammation
K Ley
2001
Involvement of IL-6, Apart from Its Role in Immunity, in Mediating a Chronic Response during Experimental Arthritis
AS de Hooge, FA van de Loo, OJ Arntz, WB van Berg
The American Journal of Pathology 2000
Polymorphonuclears: structure, function, and mechanisms of involvement in skin diseases
P Driesch
Clinics in Dermatology 2000
URINARY SOLUBLE IL-6 RECEPTOR LEVELS AFTER CARDIOPULMONARY BYPASS
AG Sutherland, DJ Deehan
Cytokine 2000
Cytokine signaling-regulation of the immune response in normal and critically ill states:
A Oberholzer, C Oberholzer, LL Moldawer
Critical Care Medicine 2000
INTERLEUKIN-13 PROTECTS ENDOTHELIAL CELLS FROM APOPTOSIS AND ACTIVATION: Association with the Protective Genes A20 and A1
PC Evans, PJ Kilshaw
Transplantation 2000
Cellular Mechanisms in Airways Inflammation
CP Page, KH Banner, D Spina
2000
Synergism of multiple adhesion molecules in mediating cytoadherence of Plasmodium falciparum–infected erythrocytes to microvascular endothelial cells under flow
BG Yipp, S Anand, T Schollaardt, KD Patel, S Looareesuwan, M Ho
Blood 2000
New developments in IL-6 dependent biology and therapy: where do we stand and what are the options?
KJ Kallen, PR Galle, S Rose-John
Expert Opinion on Investigational Drugs 1999
C-reactive protein: a physiological activator of interleukin 6 receptor shedding
SA Jones, D Novick, S Horiuchi, N Yamamoto, AJ Szalai, GM Fuller
Journal of Experimental Medicine 1999
Selective Proteolytic Cleavage of IL-2 Receptor and IL-6 Receptor Ligand Binding Chains by Neutrophil-Derived Serine Proteases at Foci of Inflammation
U Bank, D Reinhold, C Schneemilch, D Kunz, HJ Synowitz, S Ansorge
Journal of Interferon & Cytokine Research 1999
Interleukin-6 expression and regulation in astrocytes
NJ van Wagoner, EN Benveniste
Journal of Neuroimmunology 1999
Adhesion molecule expression and regulation on cells of the central nervous system
SJ Lee, EN Benveniste
Journal of Neuroimmunology 1999
Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors
P März, U Otten, S Rose-John
European Journal of Neuroscience 1999
C-reactive Protein: A Physiological Activator of Interleukin 6 Receptor Shedding
SA Jones, D Novick, S Horiuchi, N Yamamoto, AJ Szalai, GM Fuller
Journal of Experimental Medicine 1999
Divergent inducible expression of P-selectin and E-selectin in mice and primates
L Yao, H Setiadi, L Xia, Z Laszik, FB Taylor, RP McEver
Blood 1999
Endothelial Activation in ARDS
GA Zimmerman, KH Albertine, HJ Carveth, EA Gill, CK Grissom, JR Hoidal, T Imaizumi, CG Maloney, TM McIntyre, JR Michael, JF Orme, SM Prescott, MS Topham
Chest 1999
Biology of the Arterial Wall
BI Levy, A Tedgui
1999
Cytokine Actions in the Central Nervous System
EN Benveniste
Cytokine & Growth Factor Reviews 1998
Shedding of the soluble IL-6 receptor is triggered by Ca2+ mobilization, while basal release is predominantly the product of differential mRNA splicing in THP-1 cells
SA Jones, S Horiuchi, D Novick, N Yamamoto, GM Fuller
European Journal of Immunology 1998

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