We attempted to elicit active anaphylaxis to ovalbumin, or passive IgE- or IgG1-dependent anaphylaxis, in mice lacking either the Fc epsilonRI alpha chain or the FcR gamma chain common to Fc epsilonRI and Fc gammaRI/III, or in mice lacking mast cells (KitW/ KitW-v mice), and compared the responses to those in the corresponding wild-type mice. We found that the FcR gamma chain is required for the death, as well as for most of the pathophysiological changes, associated with active anaphylaxis or IgE- or IgG1-dependent passive anaphylaxis. Moreover, some of the physiological changes associated with either active, or IgG1-dependent passive, anaphylactic responses were significantly greater in Fc epsilonRI alpha chain -/- mice than in the corresponding normal mice. Finally, while both KitW/KitW-v and congenic +/+ mice exhibited fatal active anaphylaxis, mast cell-deficient mice exhibited weaker physiological responses than the corresponding wild-type mice in both active and IgG1-dependent passive systemic anaphylaxis. Our findings strongly suggest that while IgE antibodies and Fc epsilonRI may influence the intensity and/or kinetics of some of the pathophysiological changes associated with active anaphylaxis in the mouse, the mortality associated with this response can be mediated largely by IgG1 antibodies and Fc gammaRIII.
I Miyajima, D Dombrowicz, T R Martin, J V Ravetch, J P Kinet, S J Galli
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Food and Chemical Toxicology | 2013 |
A BALB/c mouse model for assessing the potential allergenicity of proteins: comparison of allergen dose, sensitization frequency, timepoint and sex
C Chen, N Sun, Y Li, X Jia |
Food and Chemical Toxicology | 2013 |
Current challenges and opportunities in nonclinical safety testing of biologics
S Kronenberg, A Baumann, L Haan, HJ Hinton, J Moggs, FP Theil, I Wakefield, T Singer |
Drug Discovery Today | 2013 |
An IgE receptor mimetic peptide (PepE) protects mice from IgE mediated anaphylaxis
JS Zhou, A Sandomenico, V Severino, OT Burton, A Darling, HC Oettgen, M Ruvo |
Molecular BioSystems | 2013 |
Antiallergic and Antiarthritic Effects of Stem Bark Extract of Glyphaea brevis (Spreng) Monachino (Tiliaceae) in Murine Models
DD Obiri, N Osafo, RE Abotsi |
ISRN Pharmacology | 2013 |
IgG and IgE Collaboratively Accelerate Expulsion of Strongyloides venezuelensis in a Primary Infection
M Matsumoto, Y Sasaki, K Yasuda, T Takai, M Muramatsu, T Yoshimoto, K Nakanishi, JF Urban |
Infection and immunity | 2013 |
Mast Cells are Important Modifiers of Autoimmune Disease: With so Much Evidence, Why is There Still Controversy?
MA Brown, JK Hatfield |
Frontiers in immunology | 2012 |
Mast cells in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis
M Costanza, MP Colombo, R Pedotti |
International journal of molecular sciences | 2012 |
Mast Cells and Company
F Jönsson, M Daëron |
Frontiers in immunology | 2012 |
New models for analyzing mast cell functions in vivo
LL Reber, T Marichal, SJ Galli |
Trends in Immunology | 2012 |
Properties of mouse and human IgG receptors and their contribution to disease models
P Bruhns |
Blood | 2012 |
Intestinal Mast Cell Levels Control Severity of Oral Antigen-Induced Anaphylaxis in Mice
R Ahrens, H Osterfeld, D Wu, CY Chen, M Arumugam, K Groschwitz, R Strait, Y Wang, FD Finkelman, SP Hogan |
The American Journal of Pathology | 2012 |
Food-induced anaphylaxis: mast cells as modulators of anaphylactic severity
SP Hogan, YH Wang, R Strait, FD Finkelman |
Seminars in Immunopathology | 2012 |
Fcγ Receptors Inhibit Mouse and Human Basophil Activation
L Cassard, F Jönsson, S Arnaud, M Daëron |
Journal of immunology (Baltimore, Md. : 1950) | 2012 |
The Contribution of Allergen-Specific IgG to the Development of Th2-Mediated Airway Inflammation
JW Williams, MY Tjota, AI Sperling |
Journal of allergy | 2012 |
Epoxyeicosatrienoic acids are involved in the C(70) fullerene derivative-induced control of allergic asthma
SK Norton, DS Wijesinghe, A Dellinger, J Sturgill, Z Zhou, S Barbour, C Chalfant, DH Conrad, CL Kepley |
Journal of Allergy and Clinical Immunology | 2012 |
Human FcγRIIA induces anaphylactic and allergic reactions
F Jönsson, DA Mancardi, W Zhao, Y Kita, B Iannascoli, H Khun, N Rooijen, T Shimizu, LB Schwartz, M Daëron, P Bruhns |
Blood | 2012 |
CD200/CD200R Paired Potent Inhibitory Molecules Regulating Immune and Inflammatory Responses; Part II : CD 200/CD200R Potential Clinical Applications
D Holmannová, M Koláčková, K Kondělková, P Kuneš, J Krejsek, C Andrýs |
Acta Medica (Hradec Kralove, Czech Republic) | 2012 |
Human Fc RIIA at center stage
T Kawakami |
Blood | 2012 |
The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling
NA Pullen, YT Falanga, JK Morales, JJ Ryan |
Frontiers in immunology | 2012 |
Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis
YT Falanga, NS Chaimowitz, N Charles, FD Finkelman, NA Pullen, S Barbour, K Dholaria, T Faber, M Kolawole, B Huang, S Odom, J Rivera, J Carlyon, DH Conrad, S Spiegel, CA Oskeritzian, JJ Ryan |
Journal of immunology (Baltimore, Md. : 1950) | 2012 |
Caffeic acid phenethyl ester attenuates IgE-induced immediate allergic reaction
MA Nader |
Inflammopharmacology | 2012 |
Anti-allergic effect of a chloroform-soluble extract of <i>Cinnamomum cambodianum</i> in bone marrow-derived mast cells
HS Chae, P Khiev, HK Lee, SR Oh, YW Chin |
Immunopharmacology and Immunotoxicology | 2012 |
Anti-allergic effects of nilotinib on mast cell–mediated anaphylaxis like reactions
DS El-Agamy |
European Journal of Pharmacology | 2012 |
Effective induction of oral anaphylaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate
T Shindo, Y Kanazawa, Y Saito, K Kojima, M Ohsawa, R Teshima |
The Journal of Toxicological Sciences | 2012 |
Basophils and mast cells play critical roles for leukocyte recruitment in IgE-mediated cutaneous reverse passive Arthus reaction
G Jin, T Matsushita, Y Hamaguchi, DL Huu, T Ishii, M Hasegawa, K Obata, H Karasuyama, K Takehara, M Fujimoto |
Journal of Dermatological Science | 2012 |
Mast cells and IgE activation do not alter the development of oral tolerance in a murine model
MC Tunis, W Dawicki, KR Carson, J Wang, JS Marshall |
Journal of Allergy and Clinical Immunology | 2012 |
Anti-Inflammatory and Anti-Allergic Effect of Agaricus blazei Extract in Bone Marrow-Derived Mast Cells
HH Song, HS Chae, SR Oh, HK Lee, YW Chin |
The American journal of Chinese medicine | 2012 |
Les IgG, leurs récepteurs et les neutrophiles : acteurs de la réaction anaphylactique ?
P Bruhns |
Revue Française d'Allergologie | 2012 |
Comparisons of serum total IgE, IgG, and IgG1 levels in patients with and without echinococcosis-induced anaphylactic shock
Y Li, H Zheng, M Gu, X Cao, H Wen, Z Liu, T Liu |
The American journal of tropical medicine and hygiene | 2012 |
The role of sphingosine 1-phosphate in immunity and sepsis
MH Gräler |
American Journal of Clinical and Experimental Immunology | 2012 |
Neutrophils as Inducers of Anaphylaxis
Friederike Jönsson, David A. Mancardi, Yoshihiro Kita, Hajime Karasuyama, Bruno Iannascoli, Nico van Rooijen, Takao Shimizu, Marc Daëron, Pierre Bruhns |
Journal of Clinical Investigation | 2011 |
Identification of markers that distinguish IgE- from IgG-mediated anaphylaxis
MV Khodoun, R Strait, L Armstrong, N Yanase, FD Finkelman |
Proceedings of the National Academy of Sciences | 2011 |
Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases
OT Burton, HC Oettgen |
Immunological Reviews | 2011 |
Mast Cells as Cellular Sensors in Inflammation and Immunity
W Beghdadi, LC Madjene, M Benhamou, N Charles, G Gautier, P Launay, U Blank |
Frontiers in immunology | 2011 |
Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria
A Porcherie, C Mathieu, R Peronet, E Schneider, J Claver, PH Commere, H Kiefer-Biasizzo, H Karasuyama, G Milon, M Dy, JP Kinet, J Louis, U Blank, S Mécheri |
Journal of Experimental Medicine | 2011 |
Antigen-fixed leukocytes tolerize Th2 responses in mouse models of allergy
CB Smarr, CL Hsu, AJ Byrne, SD Miller, PJ Bryce |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
Basophils Are the Major Producers of IL-4 during Primary Helminth Infection
N van Panhuys, M Prout, E Forbes, B Min, WE Paul, GL Gros |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
Nonredundant Roles of Basophils in Immunity
H Karasuyama, K Mukai, K Obata, Y Tsujimura, T Wada |
Annual Review of Immunology | 2011 |
[An unexpected role for neutrophils in anaphylaxis]
F Jönsson, DA Mancardi, M Daëron, P Bruhns |
médecine/sciences | 2011 |
Neutrophils give us a shock
CA Lowell |
Journal of Clinical Investigation | 2011 |
Deciphering the structure and function of FcεRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigm
J Manikandan, N Kothandaraman, MP Hande, PN Pushparaj |
Cellular and Molecular Life Sciences | 2011 |
Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice
K Arias, DK Chu, K Flader, F Botelho, T Walker, N Arias, AA Humbles, AJ Coyle, HC Oettgen, HD Chang, NV Rooijen, S Waserman, M Jordana |
Journal of Allergy and Clinical Immunology | 2011 |
Newly appreciated roles for basophils in allergy and protective immunity
H Karasuyama, K Obata, T Wada, Y Tsujimura, K Mukai |
Allergy | 2011 |
Mesenteric lymph node transcriptome profiles in BALB/c mice sensitized to three common food allergens
M Husain, HJ Boermans, NA Karrow |
BMC Genomics | 2011 |
Environmental cigarette smoke exposure modulates IgE levels of Pb-exposed children
PM Lutz, EA Kelty, TD Brown, TJ Wilson, G Brock, R Neal |
Toxicology | 2011 |
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
Effects of Lactobacillus rhamnosus GG supplementation on cow's milk allergy in a mouse model
CL Thang, B Baurhoo, JI Boye, BK Simpson, X Zhao |
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology | 2011 |
Demographic and Clinical Characteristics of Patients with Anaphylactic Shock after Surgery for Cystic Echinococcosis
Y Li, X Cao, L Chen, H Zheng, Z Liu |
The American journal of tropical medicine and hygiene | 2011 |
Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock
Ana Olivera, Christoph Eisner, Yoshiaki Kitamura, Sandra Dillahunt, Laura Allende, Galina Tuymetova, Wendy Watford, Francoise Meylan, Susanne Diesner, Lingli Li, Jurgen Schnermann, Richard Proia, Juan Rivera |
Journal of Clinical Investigation | 2010 |
An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E–mediated immediate hypersensitivity reactions
K Hitomi, S Tahara-Hanaoka, S Someya, A Fujiki, H Tada, T Sugiyama, S Shibayama, K Shibuya, A Shibuya |
Nature Immunology | 2010 |
IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling
CB Mathias, SA Hobson, M Garcia-Lloret, G Lawson, D Poddighe, EJ Freyschmidt, W Xing, MF Gurish, TA Chatila, HC Oettgen |
Journal of Allergy and Clinical Immunology | 2010 |
Basophils and the T helper 2 environment can promote the development of lupus nephritis
N Charles, D Hardwick, E Daugas, GG Illei, J Rivera |
Nature Medicine | 2010 |
PAS-1, an Ascaris suum Protein, Modulates Allergic Airway Inflammation via CD8+ γδTCR+ and CD4+ CD25+ FoxP3+ T Cells
CA de Araújo, A Perini, MA Martins, MS Macedo, MF Macedo-Soares |
Scandinavian Journal of Immunology | 2010 |
Murine B cells regulate serum IgE levels in a CD23-dependent manner
LE Cheng, ZE Wang, RM Locksley |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
Inhibitory effect of glycoprotein isolated from Opuntia ficus-indica var. saboten MAKINO on activities of allergy-mediators in compound 48/80-stimulated mast cells
KT Lim |
Cellular Immunology | 2010 |
IgG-mediated systemic anaphylaxis to protein antigen can be induced even under conditions of limited amounts of antibody and antigen
R Ishikawa, Y Tsujimura, K Obata, Y Kawano, Y Minegishi, H Karasuyama |
Biochemical and Biophysical Research Communications | 2010 |
Forsythia suspensa extract alleviates hypersensitivity induced by soybean β-conglycinin in weaned piglets
Y Hao, D Li, X Piao, X Piao |
Journal of Ethnopharmacology | 2010 |
Review of animal models designed to predict the potential allergenicity of novel proteins in genetically modified crops
GS Ladics, LM Knippels, AH Penninks, GA Bannon, RE Goodman, C Herouet-Guicheney |
Regulatory Toxicology and Pharmacology | 2010 |
Anaphylaxis and Hypersensitivity Reactions
MC Castells |
2010 | |
Suppression of IgE B Cells and IgE Binding to Fc RI by Gene Therapy with Single-Chain Anti-IgE
T Ota, M Aoki-Ota, BH Duong, D Nemazee |
Journal of immunology (Baltimore, Md. : 1950) | 2009 |
Co-operation between mast cells and neurons is essential for antigen-mediated bronchoconstriction1
JM Cyphert, M Kovarova, IC Allen, JM Hartney, DL Murphy, J Wess, BH Koller |
Journal of immunology (Baltimore, Md. : 1950) | 2009 |
Displaying Fel d1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy
N Schmitz, K Dietmeier, M Bauer, M Maudrich, S Utzinger, S Muntwiler, P Saudan, MF Bachmann |
Journal of Experimental Medicine | 2009 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
IgE Influences the Number and Function of Mature Mast Cells, but Not Progenitor Recruitment in Allergic Pulmonary Inflammation
CB Mathias, EJ Freyschmidt, B Caplan, T Jones, D Poddighe, W Xing, KL Harrison, MF Gurish, HC Oettgen |
Journal of immunology (Baltimore, Md. : 1950) | 2009 |
Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction
K Nishida, A Hasegawa, S Nakae, K Oboki, H Saito, S Yamasaki, T Hirano |
Journal of Experimental Medicine | 2009 |
Rheumatoid Arthritis
IA Ku, JB Imboden, PY Hsue, P Ganz |
Circulation Journal | 2009 |
Mechanisms of mast cell signaling in anaphylaxis
DD Metcalfe, RD Peavy, AM Gilfillan |
Journal of Allergy and Clinical Immunology | 2009 |
Newly discovered roles for basophils: a neglected minority gains new respect
H Karasuyama, K Mukai, Y Tsujimura, K Obata |
Nature Reviews Immunology | 2009 |
Inhibition of allergic responses by CD40 gene silencing
M Suzuki, X Zheng, X Zhang, TE Ichim, H Sun, N Kubo, M Beduhn, A Shunnar, B Garcia, WP Min |
Allergy | 2009 |
Anaphylaxis to a self-peptide in the absence of mast cells or histamine
S Musio, P Pedotti, R Mantegazza, H Ohtsu, L Boon, L Steinman, SJ Galli, R Pedotti |
Laboratory Investigation | 2009 |
Mast Cells
HP Kiener, PA Nigrovic, DM Lee |
Rheumatoid Arthritis | 2009 |
Anti-allergic effects of Teucrium japonicum on mast cell-mediated allergy model
SH Kim, SB Park, SM Kang, H Jeon, JP Lim, TK Kwon, WH Park, HM Kim, TY Shin |
Food and Chemical Toxicology | 2009 |
Sensitization of skin mast cells with IgE antibodies to Culicoides allergens occurs frequently in clinically healthy horses
B Wagner, WH Miller, HN Erb, DP Lunn, DF Antczak |
Veterinary Immunology and Immunopathology | 2009 |
Middleton's Allergy: Principles and Practice
RP Schleimer |
Middleton's Allergy: Principles and Practice | 2009 |
Kelley's Textbook of Rheumatology
J Degroot, AM Zuurmond, PP Tak |
Kelley's Textbook of Rheumatology | 2009 |
Importance of basophil activation testing in insect venom allergy
M Kosnik, P Korosec |
Allergy Asthma & Clinical Immunology | 2009 |
Ailanthus altissima swingle has anti-anaphylactic effect and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation
TH Kang, IY Choi, SJ Kim, PD Moon, JU Seo, JJ Kim, NH An, SH Kim, MH Kim, JY Um, SH Hong, HM Kim, HJ Jeong |
In vitro cellular & developmental biology. Animal | 2009 |
Cancer and IgE
ML Penichet, E Jensen-Jarolim |
2009 | |
CD4+CD25+ regulatory T cells specific for a thymus-expressed antigen prevent the development of anaphylaxis to self
S Scabeni, M Lapilla, S Musio, B Gallo, E Ciusani, L Steinman, R Mantegazza, R Pedotti |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity
EE Forbes, K Groschwitz, JP Abonia, EB Brandt, E Cohen, C Blanchard, R Ahrens, L Seidu, A McKenzie, R Strait, FD Finkelman, PS Foster, KI Matthaei, ME Rothenberg, SP Hogan |
Journal of Experimental Medicine | 2008 |
Sialic Acid Residues Are Essential for the Anaphylactic Activity of Murine IgG1 Antibodies
SR Silva, A Casabuono, JF Jacysyn, BC Favoretto, I Fernandes, MS Macedo, AS Couto, EL Faquim-Mauro |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Using guinea pigs in studies relevant to asthma and COPD
BJ Canning, Y Chou |
Pulmonary Pharmacology & Therapeutics | 2008 |
VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways
N Tiwari, CC Wang, C Brochetta, G Ke, F Vita, Z Qi, J Rivera, MR Soranzo, G Zabucchi, W Hong, U Blank |
Blood | 2008 |
Basophils Play a Pivotal Role in Immunoglobulin-G-Mediated but Not Immunoglobulin-E-Mediated Systemic Anaphylaxis
Y Tsujimura, K Obata, K Mukai, H Shindou, M Yoshida, H Nishikado, Y Kawano, Y Minegishi, T Shimizu, H Karasuyama |
Immunity | 2008 |
FcγRIIIa-V/F 158 polymorphism in Turkish children with asthma bronchiale and allergic rhinitis
D Zeyrek, R Tanac, S Altinoz, A Berdeli, F Gulen, H Koksoy, E Demir |
Pediatric Allergy and Immunology | 2008 |
Anti-allergic effect of bee pollen phenolic extract and myricetin in ovalbumin-sensitized mice
KC Medeiros, CA Figueiredo, TB Figueredo, KR Freire, FA Santos, NM Alcantara-Neves, TM Silva, MR Piuvezam |
Journal of Ethnopharmacology | 2008 |
Hypothesis: hemolytic transfusion reactions represent an alternative type of anaphylaxis
EA Hod, SA Sokol, JC Zimring, SL Spitalnik |
International journal of clinical and experimental pathology | 2008 |
Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection
K Shin, GF Watts, HC Oettgen, DS Friend, AD Pemberton, MF Gurish, DM Lee |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Basophils Are Back!
SJ Galli, CB Franco |
Immunity | 2008 |
Basophils enhance immunological memory responses
A Denzel, UA Maus, MR Gomez, C Moll, M Niedermeier, C Winter, R Maus, S Hollingshead, DE Briles, LA Kunz-Schughart, Y Talke, M Mack |
Nature Immunology | 2008 |
High dose of lipopolysaccharide pre-treatment prevents OVA-induced anaphylactic decreases in rectal temperature in the immunized mice
D Shiva, T Matsumoto, MJ Kremenik, Y Kato, H Yano |
Immunology Letters | 2008 |
Novel vaccination for allergy through gene silencing of CD40 using small interfering RNA
M Suzuki, X Zheng, X Zhang, M Li, C Vladau, TE Ichim, H Sun, LR Min, B Garcia, WP Min |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Dissociation of experimental allergic encephalomyelitis protective effect and allergic side reactions in tolerization with neuroantigen
FS Lichtenegger, S Kuerten, S Faas, BO Boehm, M Tary-Lehmann, PV Lehmann |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1
PA Nigrovic, BA Binstadt, PA Monach, A Johnsen, M Gurish, Y Iwakura, C Benoist, D Mathis, DM Lee |
Proceedings of the National Academy of Sciences | 2007 |
Mast cells in the promotion and limitation of chronic inflammation
M Metz, MA Grimbaldeston, S Nakae, AM Piliponsky, M Tsai, SJ Galli |
Immunological Reviews | 2007 |
Inhibitory Effects of Phyto Extract Mixture (PEM381) on Type I Allergic Reaction
KB Kim, EG Lee, OH Chai, CH Song, JM Jeong |
Journal of the Korean Society of Food Science and Nutrition | 2007 |
Effects of Phyto-Extract Mixture (PEM381) in Type I Allergic Reaction-Induced Mice
KB Kim, JS Park, JM Jeong |
Journal of the Korean Society of Food Science and Nutrition | 2007 |
Inhibition of pathologic inflammation by leukocyte Ig-like receptor B4 and related inhibitory receptors
HR Katz |
Immunological Reviews | 2007 |
Effects of Triterpenoid-Rich Extracts of <i>Ganoderma tsugae</i> on Airway Hyperreactivity and Th2 Responses in vivo
ML Chen, BF Lin |
International Archives of Allergy and Immunology | 2007 |
Role of mast cell degranulation in the neural correlates of the immediate allergic reaction in a murine model of asthma
FA Costa-Pinto, AS Basso, M Russo |
Brain, Behavior, and Immunity | 2007 |
Anaphylaxis: Lessons from mouse models
FD Finkelman |
Journal of Allergy and Clinical Immunology | 2007 |
Oral allergy syndrome and anaphylactic reactions in BALB/c mice caused by soybean glycinin and β-conglycinin
X Liu, J Feng, ZR Xu, YZ Wang, JX Liu |
Clinical & Experimental Allergy | 2007 |
Immunotherapy with CpG DNA conjugated with T-cell epitope peptide of an allergenic Cry j 2 protein is useful for control of allergic conditions in mice
M Suzuki, N Ohta, WP Min, T Matsumoto, R Min, X Zhang, K Toida, S Murakami |
International Immunopharmacology | 2007 |
Suppression of mast cell-mediated allergic reaction by Amomum xanthiodes
SH Kim, S Lee, IK Kim, TK Kwon, JY Moon, WH Park, TY Shin |
Food and Chemical Toxicology | 2007 |
The FcγRIIa polymorphism in Turkish children with asthma bronchial and allergic rhinitis
F Gulen, R Tanac, S Altinoz, A Berdeli, D Zeyrek, H Koksoy, E Demir |
Clinical Biochemistry | 2007 |
The roles of mast cells and Kupffer cells in rat systemic anaphylaxis
T Shibamoto, T Shimo, S Cui, W Zhang, H Takano, Y Kurata, H Tsuchida |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2007 |
Large defects of type I allergic response in telomerase reverse transcriptase knockout mice
A Ujike-Asai, A Okada, Y Du, M Maruyama, X Yuan, F Ishikawa, Y Motoo, K Isobe, H Nakajima |
Journal of leukocyte biology | 2007 |
Impact of CD40 Ligand, B Cells, and Mast Cells in Peanut-Induced Anaphylactic Responses
J Sun, K Arias, D Alvarez, R Fattouh, T Walker, S Goncharova, B Kim, S Waserman, J Reed, AJ Coyle, M Jordana |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
CD4 + T Cell-Specific Deletion of IL-4 Receptor α Prevents Ovalbumin-Induced Anaphylaxis by an IFN-γ-Dependent Mechanism
N Nieuwenhuizen, DB Herbert, AL Lopata, F Brombacher |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
Mast cells can promote the development of multiple features of chronic asthma in mice
Mang Yu, Mindy Tsai, See-Ying Tam, Carol Jones, James Zehnder and Stephen J. Galli |
Journal of Clinical Investigation | 2006 |
Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses
MA Grimbaldeston, M Metz, M Yu, M Tsai, SJ Galli |
Current Opinion in Immunology | 2006 |
Critical Role of the Fc Receptor γ-Chain on APCs in the Development of Allergen-Induced Airway Hyperresponsiveness and Inflammation
K Kitamura, K Takeda, T Koya, N Miyahara, T Kodama, A Dakhama, T Takai, A Hirano, M Tanimoto, M Harada, EW Gelfand |
Journal of immunology (Baltimore, Md. : 1950) | 2006 |
Current Protocols in Pharmacology
JP Renninger |
Current Protocols in Pharmacology | 2006 |
A canine model of cutaneous late-phase reactions: prednisolone inhibition of cellular and cytokine responses
CM Pucheu-Haston, D Shuster, T Olivry, P Brianceau, P Lockwood, T McClanahan, RW Malefyt, JD Mattson, B Hammerberg |
Immunology | 2006 |
Particularities of the vasculature can promote the organ specificity of autoimmune attack
BA Binstadt, PR Patel, H Alencar, PA Nigrovic, DM Lee, U Mahmood, R Weissleder, D Mathis, C Benoist |
Nature Immunology | 2006 |
Action of Dracocephalum argunense on Mast Cell-Mediated Allergy Model
SH Kim, SH Kim, SH Kim, JY Moon, WH Park, CH Kim, TY Shin |
Biological & Pharmaceutical Bulletin | 2006 |
Artemisia iwayomogiInhibits Immediate-Type Allergic Reaction and Inflammatory Cytokine Secretion
TY Shin, JS Park, SH Kim |
Immunopharmacology and Immunotoxicology | 2006 |
FcγRIIa, Not FcγRIIb, Is Constitutively and Functionally Expressed on Skin-Derived Human Mast Cells
W Zhao, CL Kepley, PA Morel, LM Okumoto, Y Fukuoka, LB Schwartz |
Journal of immunology (Baltimore, Md. : 1950) | 2006 |
Pathophysiology of Urticaria
A Hennino, F Bérard, I Guillot, N Saad, A Rozières, JF Nicolas |
Clinical Reviews in Allergy & Immunology | 2006 |
Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle
JP Abonia, DS Friend, WG Austen, FD Moore, MC Carroll, R Chan, J Afnan, A Humbles, C Gerard, P Knight, Y Kanaoka, S Yasuda, N Morokawa, KF Austen, RL Stevens, MF Gurish |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis
CE Smith, TN Eagar, JL Strominger, SD Miller |
Proceedings of the National Academy of Sciences | 2005 |
Rapidly changing perspectives about mast cells at mucosal surfaces
H Vliagoftis, AD Befus |
Immunological Reviews | 2005 |
MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances
SJ Galli, J Kalesnikoff, MA Grimbaldeston, AM Piliponsky, CM Williams, M Tsai |
Annual Review of Immunology | 2005 |
Elicitation of allergic asthma by immunoglobulin free light chains
AD Kraneveld, M Kool, AH van Houwelingen, P Roholl, A Solomon, DS Postma, FP Nijkamp, FA Redegeld |
Proceedings of the National Academy of Sciences | 2005 |
The allergy adjuvant effect of particles - genetic factors influence antibody and cytokine responses
UC Nygaard, A Aase, M Løvik |
BMC Immunology | 2005 |
Peanut-lupine antibody cross-reactivity is not associated to cross-allergenicity in peanut-sensitized mouse strains
A Lifrani, M Dubarry, M Rautureau, N Aattouri, PN Boyaka, D Tomé |
International Immunopharmacology | 2005 |
Dietary unripe apple polyphenol inhibits the development of food allergies in murine models
H Akiyama, Y Sato, T Watanabe, MH Nagaoka, Y Yoshioka, T Shoji, T Kanda, K Yamada, M Totsuka, R Teshima, J Sawada, Y Goda, T Maitani |
FEBS Letters | 2005 |
Comparison of asthma phenotypes using different sensitizing protocols in mice
YS Chang, YK Kim, JW Bahn, SH Kim, HW Park, TB Kim, SH Cho, KU Min, YY Kim |
The Korean Journal of Internal Medicine | 2005 |
Comparison of Asthma Phenotypes Using Different Sensitizing Protocols in Mice
YS Chang, YK Kim, JW Bahn, SH Kim, HW Park, TB Kim, SH Cho, KU Min, YY Kim |
The Korean Journal of Internal Medicine | 2005 |
Anti-Allergic Effects of Artemisia iwayomogi on Mast Cell-Mediated Allergy Model
SH Kim, CH Choi, SY Kim, JS Eun, TY Shin |
Experimental biology and medicine (Maywood, N.J.) | 2005 |
Amomum xanthiodes Inhibits Mast Cell-Mediated Allergic Reactions Through the Inhibition of Histamine Release and Inflammatory Cytokine Production
SH Kim, TY Shin |
Experimental biology and medicine (Maywood, N.J.) | 2005 |
Mast Cell Survival and Activation by IgE in the Absence of Antigen: A Consideration of the Biologic Mechanisms and Relevance
T Kawakami, J Kitaura |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Identification of Antigen-Capturing Cells as Basophils
M Mack, MA Schneider, C Moll, J Cihak, H Brühl, JW Ellwart, MP Hogarth, M Stangassinger, D Schlöndorff |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
Lung eosinophilic inflammation and airway hyperreactivity are enhanced by murine anaphylactic, but not nonanaphylactic, IgG1 antibodies
MF Macedo-Soares, DM Itami, C Lima, A Perini, EL Faquim-Mauro, MA Martins, MS Macedo |
Journal of Allergy and Clinical Immunology | 2004 |
WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells
A Kettner, L Kumar, IM Antón, Y Sasahara, M la Fuente, VI Pivniouk, H Falet, JH Hartwig, RS Geha |
Journal of Experimental Medicine | 2004 |
Allergen-independent immunostimulatory sequence oligodeoxynucleotide therapy attenuates experimental allergic rhinitis
CS Rhee, L Libet, D Chisholm, K Takabayashi, S Baird, TD Bigby, CH Lee, AA Horner, E Raz |
Immunology | 2004 |
Absence of interleukin-3 does not affect the severity of local and systemic anaphylaxis but does enhance eosinophil infiltration in a mouse model of allergic peritonitis
NF Neel, BM Creasy, JN Rankin, EM Pierce, ME McCoy, RH Daner, JA Fowler, JC Daniel, CS Lantz |
Immunology Letters | 2004 |
Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites
FD Finkelman, T Shea-Donohue, SC Morris, L Gildea, R Strait, KB Madden, L Schopf, JF Urban |
Immunological Reviews | 2004 |
Animal Models for the Study of Allergy
R Helm |
Handbook of Laboratory Animal Science Second Edition Animal Models Volume III | 2004 |
Handbook of Laboratory Animal Science, Second Edition: Animal Models, Volume III
R Helm |
Handbook of Laboratory Animal Science, Second Edition: Animal Models, Volume III | 2004 |
Skin Immune System: Cutaneous Immunology and Clinical Immunodermatology, Third Edition
E Guigné, J Revuz, JC Roujeau |
Skin Immune System: Cutaneous Immunology and Clinical Immunodermatology, Third Edition | 2004 |
Basophils initiate IL-4 production during a memory T-dependent response
MV Khodoun, T Orekhova, C Potter, S Morris, FD Finkelman |
Journal of Experimental Medicine | 2004 |
Mast Cell-Independent Mechanisms of Immediate Hypersensitivity: A Role for Platelets
DC Cara, KV Ebbert, DM McCafferty |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity
D Artis, A Villarino, M Silverman, W He, EM Thornton, S Mu, S Summer, TM Covey, E Huang, H Yoshida, G Koretzky, M Goldschmidt, GD Wu, F de Sauvage, HR Miller, CJ Saris, P Scott, CA Hunter |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
Mast cells are required for experimental oral allergen-induced diarrhea
Eric B. Brandt, Richard T. Strait, Dan Hershko, Quan Wang, Emily E. Muntel, Troy A. Scribner, Nives Zimmermann, Fred D. Finkelman, Marc E. Rothenberg. |
Journal of Clinical Investigation | 2003 |
Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus
R Pedotti, M Sanna, M Tsai, J DeVoss, L Steinman, H McDevitt, SJ Galli |
BMC Immunology | 2003 |
gammadelta T cells contribute to the systemic immunoglobulin E response and local B-cell reactivity in allergic eosinophilic airway inflammation
L Svensson, B Lilliehöök, R Larsson, A Bucht |
Immunology | 2003 |
THEBIOLOGY OFIGEAND THEBASIS OFALLERGICDISEASE
HJ Gould, BJ Sutton, AJ Beavil, RL Beavil, N McCloskey, HA Coker, D Fear, L Smurthwaite |
Annual Review of Immunology | 2003 |
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
R Pedotti, JJ DeVoss, S Youssef, D Mitchell, J Wedemeyer, R Madanat, H Garren, P Fontoura, M Tsai, SJ Galli, RA Sobel, L Steinman |
Proceedings of the National Academy of Sciences | 2003 |
Involvement of both ‘allergic’ and ‘autoimmune’ mechanisms in EAE, MS and other autoimmune diseases
R Pedotti, JJ de Voss, L Steinman, SJ Galli |
Trends in Immunology | 2003 |
IL-4 selectively enhances FcγRIII expression and signaling on mouse mast cells
HJ Chong, LA Bouton, DP Bailey, H Wright, C Ramirez, A Gharse, C Oskeritzian, HZ Xia, J Zhu, WE Paul, C Kepley, LB Schwartz, JJ Ryan |
Cellular Immunology | 2003 |
Animal Models of Allergen and Virus-Induced Asthma
J Schwarze, E Gelfand |
Respiratory Infections in Allergy and Asthma | 2003 |
Advances in mechanisms of allergy
BS Bochner, Q Hamid |
Journal of Allergy and Clinical Immunology | 2003 |
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
Evaluation of the immune response to CRA and FRA recombinant antigens of Trypanosoma cruzi in C57BL/6 mice
VR Pereira, VM de Lorena, M Nakazawa, AP da Silva, U Montarroyos, R Correa-Oliveira, Y de Miranda Gomes |
Revista da Sociedade Brasileira de Medicina Tropical | 2003 |
Cutting Edge: Both Activating and Inhibitory Fc Receptors Expressed on Mast Cells Regulate Experimental Allergic Encephalomyelitis Disease Severity
M Robbie-Ryan, MB Tanzola, VH Secor, MA Brown |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
IgE-Mediated Activation of NK Cells Through FcγRIII
N Arase, H Arase, S Hirano, T Yokosuka, D Sakurai, T Saito |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
Anti-Peptide Autoantibodies and Fatal Anaphylaxis with Insulin Self-Peptides B:9-23 and B:13-23
Edwin Liu, Hiroaki Moriyama, Norio Abiru, Dongmei Miao, Liping Yu, Robert M. Taylor, Fred D. Finkelman, George S. Eisenbarth |
Journal of Clinical Investigation | 2002 |
Cytokines Regulate Development of Human Mast Cells from Hematopoietic Progenitors
T Nakahata, H Toru |
International Journal of Hematology | 2002 |
Analyzing the Roles of Mast Cells and Basophils in Host Defense and Other Biological Responses
SJ Galli, J Wedemeyer, M Tsai |
International Journal of Hematology | 2002 |
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
C Lock, G Hermans, R Pedotti, A Brendolan, E Schadt, H Garren, A Langer-Gould, S Strober, B Cannella, J Allard, P Klonowski, A Austin, N Lad, N Kaminski, SJ Galli, JR Oksenberg, CS Raine, R Heller, L Steinman |
Nature Medicine | 2002 |
Inhibitory receptors and allergy
HR Katz |
Current Opinion in Immunology | 2002 |
FcγRI (CD64) Contributes Substantially to Severity of Arthritis, Hypersensitivity Responses, and Protection from Bacterial Infection
A Ioan-Facsinay, SJ Kimpe, SM Hellwig, PL Lent, FM Hofhuis, HH Ojik, C Sedlik, SA Silveira, J Gerber, YF Jong, R Roozendaal, LA Aarden, WB Berg, T Saito, D Mosser, S Amigorena, S Izui, GJ Ommen, M Vugt, JG de Winkel, JS Verbeek |
Immunity | 2002 |
IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions
H Konishi, H Tsutsui, T Murakami, S Yumikura-Futatsugi, KI Yamanaka, M Tanaka, Y Iwakura, N Suzuki, K Takeda, S Akira, K Nakanishi, H Mizutani |
Proceedings of the National Academy of Sciences | 2002 |
Accumulation of platelets in the lung and liver and their degranulation following antigen-challenge in sensitized mice
A Yoshida, M Ohba, X Wu, T Sasano, M Nakamura, Y Endo |
British Journal of Pharmacology | 2002 |
Murine models for natural rubber latex allergy assessment
BJ Meade, M Woolhiser |
Methods | 2002 |
Lactobacillus casei strain Shirota suppresses serum immunoglobulin E and immunoglobulin G1 responses and systemic anaphylaxis in a food allergy model
K Shida, R Takahashi, E Iwadate, K Takamizawa, H Yasui, T Sato, S Habu, S Hachimura, S Kaminogawa |
Clinical & Experimental Allergy | 2002 |
Effect of orally administered Hochu-ekki-to, a Japanese herbal medicine, on contact hypersensitivity caused by repeated application of antigen
T Nakada, K Watanabe, T Matsumoto, K Santa, K Triizuka, T Hanawa |
International Immunopharmacology | 2002 |
Pathways of anaphylaxis in the mouse
RT Strait, SC Morris, M Yang, XW Qu, FD Finkelman |
Journal of Allergy and Clinical Immunology | 2002 |
The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis
Y Makabe-Kobayashi, Y Hori, T Adachi, S Ishigaki-Suzuki, Y Kikuchi, Y Kagaya, K Shirato, A Nagy, A Ujike, T Takai, T Watanabe, H Ohtsu |
Journal of Allergy and Clinical Immunology | 2002 |
IgE and Anti-IgE Therapy in Asthma and Allergic Disease
D Dombrowicz, A Capron, M Capro |
IgE and Anti-IgE Therapy in Asthma and Allergic Disease: Pathogenesis and Novel Therapeutic Strategies | 2002 |
IgE and Anti-IgE Therapy in Asthma and Allergic Disease: Caveats and Conclusions on the Contribution of IgE and Mast Cells to Allergic Inflammation, Airway Hyperresponsiveness and Airflow Obstruction
J Tepper, D Tumas |
IgE and Anti-IgE Therapy in Asthma and Allergic Disease: Pathogenesis and Novel Therapeutic Strategies | 2002 |
Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses
FA Redegeld, MW van der Heijden, M Kool, BM Heijdra, J Garssen, AD Kraneveld, HV Loveren, P Roholl, T Saito, JS Verbeek, J Claassens, AS Koster, FP Nijkamp |
Nature Medicine | 2002 |
IgE-Dependent Mast Cell Activation Potentiates Airway Responses in Murine Asthma Models
SI Mayr, RI Zuberi, M Zhang, J de Sousa-Hitzler, K Ngo, Y Kuwabara, L Yu, WP Fung-Leung, FT Liu |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
Role of STAT6 in IgE Receptor/FcεRI-Mediated Late Phase Allergic Responses of Mast Cells
R Malaviya, FM Uckun |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
Early Phase Bronchoconstriction in the Mouse Requires Allergen-Specific IgG
JR Crosby, G Cieslewicz, M Borchers, E Hines, P Carrigan, JJ Lee, NA Lee |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4′-Hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: Structural Basis for Inactivation by Regioselective O -Demethylation
FM Uckun, J Thoen, H Chen, E Sudbeck, C Mao, R Malaviya, XP Liu, CL Chen |
Drug Metabolism and Disposition | 2002 |
IgE regulation and roles in asthma pathogenesis
HC Oettgen, RS Geha |
Journal of Allergy and Clinical Immunology | 2001 |
New insights into the role of cytokines in asthma
JC Renauld |
Journal of clinical pathology | 2001 |
Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice
M Daheshia, DS Friend, MJ Grusby, KF Austen, HR Katz |
Journal of Experimental Medicine | 2001 |
Lyn is essential for fcgamma receptor III-mediated systemic anaphylaxis but not for the Arthus reaction
T Yuasa, M Ono, T Watanabe, T Takai |
Journal of Experimental Medicine | 2001 |
Lyn Is Essential for Fc Receptor III-Mediated Systemic Anaphylaxis but Not for the Arthus Reaction
T Yuasa, M Ono, T Watanabe, T Takai |
Journal of Experimental Medicine | 2001 |
Examination of oral sensitization with ovalbumin in Brown Norway rats and three strains of mice
H Akiyama, R Teshima, J Sakushima, H Okunuki, Y Goda, J Sawada, M Toyoda |
Immunology Letters | 2001 |
DNA-based vaccination for the treatment of food allergy
MD Nguyen, N Cinman, J Yen, AA Horner |
Allergy | 2001 |
IGG FCRECEPTORS
JV Ravetch, S Bolland |
Annual Review of Immunology | 2001 |
Anti-IgE efficacy in murine asthma models is dependent on the method of allergen sensitization
DB Tumas, B Chan, W Werther, T Wrin, J Vennari, N Desjardin, RL Shields, P Jardieu |
Journal of Allergy and Clinical Immunology | 2001 |
Activating and Inhibitory Immunoglobulin-like Receptors
MD Cooper, T Takai, JV Ravetch |
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Neutralizing antiviral antibody responses
R M Zinkernagel, A LaMarre, A Ciurea, L Hunziker, A F Ochsenbein, K D McCoy, T Fehr, M F Bachmann, U Kalinke, H Hengartner |
Advances in immunology | 2001 |
Roles of mast cells and basophils in innate and acquired immunity
J Wedemeyer, M Tsai, SJ Galli |
Current Opinion in Immunology | 2000 |
Mast cells and basophils
SJ Galli |
Current Opinion in Hematology | 2000 |
Induction of active systemic anaphylaxis by oral sensitization with ovalbumin in mast-cell-deficient mice
H Okunuki, R Teshima, J Sakushima, H Akiyama, Y Goda, M Toyoda, J Sawada |
Immunology Letters | 2000 |
The immunologic basis for intestinal food allergy
SH Murch |
Current Opinion in Gastroenterology | 2000 |
Serum IgE response to orally ingested antigen: A novel IgE response model with allergen-specific T-cell receptor transgenic mice
K Shida, S Hachimura, A Ametani, M Ishimori, M Ling, M Hashiguchi, Y Ueda, T Sato, Y Kumagai, K Takamizawa, S Habu, S Kaminogawa |
Journal of Allergy and Clinical Immunology | 2000 |
Glucocorticoids enhance IgE synthesis. Are we heading towards new paradigms?
SS Salvi, KS Babu, ST Holgate |
Clinical & Experimental Allergy | 2000 |
The diverse potential effector and immunoregulatory roles of mast cells in allergic disease
CM Williams, SJ Galli |
Journal of Allergy and Clinical Immunology | 2000 |
DNA-based vaccination reduces the risk of lethal anaphylactic hypersensitivity in mice
AA Horner, MD Nguyen, A Ronaghy, N Cinman, S Verbeek, E Raz |
Journal of Allergy and Clinical Immunology | 2000 |
Mechanism for the Isotype Dependence of Antibody-Mediated Toxicity in Cryptococcus neoformans- Infected Mice
N Lendvai, XW Qu, W Hsueh, A Casadevall |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis
Jonathan M. Spergel, Emiko Mizoguchi, Hans Oettgen, Atul K. Bhan, Raif S. Geha |
Journal of Clinical Investigation | 1999 |
IgE in asthma and atopy: cellular and molecular connections
HC Oettgen, RS Geha |
Journal of Clinical Investigation | 1999 |
Deletion of fcgamma receptor IIB renders H-2(b) mice susceptible to collagen-induced arthritis
T Yuasa, S Kubo, T Yoshino, A Ujike, K Matsumura, M Ono, JV Ravetch, T Takai |
Journal of Experimental Medicine | 1999 |
SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells
VI Pivniouk, TR Martin, JM Lu-Kuo, HR Katz, HC Oettgen, RS Geha |
Journal of Clinical Investigation | 1999 |
Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG
A Ujike, Y Ishikawa, M Ono, T Yuasa, T Yoshino, M Fukumoto, JV Ravetch, T Takai |
Journal of Experimental Medicine | 1999 |
Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus
KJ Seidl, JP Manis, A Bottaro, J Zhang, L Davidson, A Kisselgof, H Oettgen, FW Alt |
Proceedings of the National Academy of Sciences | 1999 |
Deletion of Fc Receptor IIB Renders H-2b Mice Susceptible to Collagen-induced Arthritis
T Yuasa, S Kubo, T Yoshino, A Ujike, K Matsumura, M Ono, JV Ravetch, T Takai |
Journal of Experimental Medicine | 1999 |
Modulation of Immunoglobulin (Ig)E-mediated Systemic Anaphylaxis by Low-Affinity Fc Receptors for IgG
A Ujike, Y Ishikawa, M Ono, T Yuasa, T Yoshino, M Fukumoto, JV Ravetch, T Takai |
Journal of Experimental Medicine | 1999 |
IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs
JF Urban, N Noben-Trauth, DD Donaldson, KB Madden, SC Morris, M Collins, FD Finkelman |
Journal of immunology (Baltimore, Md. : 1950) | 1999 |
Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice
B Nieswandt, B Echtenacher, FP Wachs, J Schröder, JE Gessner, RE Schmidt, GE Grau, DN Männel |
Blood | 1999 |
Inhibition of murine IgE and immediate cutaneous hypersensitivity responses to ovalbumin by the immunomodulatory agent leflunomide
ER Jarman, A Kuba, E Montermann, RR Bartlett, AB Reske-Kunz |
Clinical & Experimental Immunology | 1999 |
Induction and regulation of the IgE response
DB Corry, F Kheradmand |
Nature | 1999 |
Targeting Janus Kinase 3 in Mast Cells Prevents Immediate Hypersensitivity Reactions and Anaphylaxis
R Malaviya, DM Zhu, I Dibirdik, FM Uckun |
The Journal of biological chemistry | 1999 |
Pharmacokinetics and biologic activity of the novel mast cell inhibitor, 4-(3-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline in mice
C L Chen, R Malaviya, C Navara, H Chen, B Bechard, G Mitcheltree, X P Liu, F M Uckun |
Pharmaceutical Research | 1999 |
DIVERGENT ROLES FOR FcRECEPTORS AND COMPLEMENT IN VIVO
JV Ravetch, RA Clynes |
Annual Review of Immunology | 1998 |
IgG-mediated anaphylaxis via Fc gamma receptor in CD40-deficient mice
H Wakayama, Y Hasegawa, T Kawabe, H Saito, H Kikutani, K Shimokata |
Clinical & Experimental Immunology | 1998 |
Regulation of secretion of IL-4 and IgG1 isotype by melatonin-stimulated ovalbumin-specific T cells
AV Shaji, SK Kulkarni, JN Agrewala |
Clinical & Experimental Immunology | 1998 |
Immunoglobulin E-dependent active fatal anaphylaxis in mast cell-deficient mice
IH Choi, YM Shin, JS Park, MS Lee, EH Han, OH Chai, SY Im, TY Ha, HK Lee |
Journal of Experimental Medicine | 1998 |
Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice
DB Corry, G Grünig, H Hadeiba, VP Kurup, ML Warnock, D Sheppard, DM Rennick, RM Locksley |
Molecular Medicine | 1998 |
Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor
S Ishii, T Kuwaki, T Nagase, K Maki, F Tashiro, S Sunaga, WH Cao, K Kume, Y Fukuchi, K Ikuta, J Miyazaki, M Kumada, T Shimizu |
Journal of Experimental Medicine | 1998 |
Allergy-Associated FcRβ Is a Molecular Amplifier of IgE- and IgG-Mediated In Vivo Responses
D Dombrowicz, S Lin, V Flamand, AT Brini, BH Koller, JP Kinet |
Immunity | 1998 |
Enzymatically Active Papain Preferentially Induces an Allergic Response in Mice
L Chambers, A Brown, DI Pritchard, S Sreedharan, K Brocklehurst, NA Kalsheker |
Biochemical and Biophysical Research Communications | 1998 |
Impaired Anaphylactic Responses with Intact Sensitivity to Endotoxin in Mice Lacking a Platelet-activating Factor Receptor
S Ishii, T Kuwaki, T Nagase, K Maki, F Tashiro, S Sunaga, WH Cao, K Kume, Y Fukuchi, K Ikuta, J Miyazaki, M Kumada, T Shimizu |
Journal of Experimental Medicine | 1998 |
Immunoglobulin E-dependent Active Fatal Anaphylaxis in Mast Cell-deficient Mice
IH Choi, YM Shin, JS Park, MS Lee, EH Han, OH Chai, SY Im, TY Ha, HK Lee |
Journal of Experimental Medicine | 1998 |
Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
DB Corry, HG Folkesson, ML Warnock, DJ Erle, MA Matthay, JP Wiener-Kronish, RM Locksley |
Journal of immunology (Baltimore, Md. : 1950) | 1998 |
Uncoupling of Immune Complex Formation and Kidney Damage in Autoimmune Glomerulonephritis
R Clynes, C Dumitru, JV Ravetch |
Science | 1998 |
Gastric inflammation during systemic anaphylaxis: neutrophil recruitment in stomach wall of mice does not require mast cell participation
G T Furuta, Z S Wang, B K Wershil |
Digestive Diseases and Sciences | 1998 |
Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chains
D Dombrowicz, V Flamand, I Miyajima, JV Ravetch, SJ Galli, JP Kinet |
Journal of Clinical Investigation | 1997 |
IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions
M Yamaguchi, CS Lantz, HC Oettgen, IM Katona, T Fleming, I Miyajima, JP Kinet, SJ Galli |
Journal of Experimental Medicine | 1997 |
Complexity and redundancy in the pathogenesis of asthma: reassessing the roles of mast cells and T cells
SJ Galli |
Journal of Experimental Medicine | 1997 |
Bronchial asthma: lessons from murine models
GJ Gleich, H Kita |
Proceedings of the National Academy of Sciences | 1997 |
Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma
PD Mehlhop, M de Rijn, AB Goldberg, JP Brewer, VP Kurup, TR Martin, HC Oettgen |
Proceedings of the National Academy of Sciences | 1997 |
The role of FcR in immunity: Lessons from gene targeting in mice
JS Verbeek, WL Hazenbos, PJ Capel, JG de Winkel |
Research in Immunology | 1997 |
Allergic Eosinophil-rich Inflammation Develops in Lungs and Airways of B Cell–deficient Mice
M Korsgren, JS ält, O Korsgren, F Sundler, CG Persson |
Journal of Experimental Medicine | 1997 |
Impaired mast cell-dependent natural immunity in complement C3-deficient mice
AP Prodeus, X Zhou, M Maurer, SJ Galli, MC Carroll |
Nature | 1997 |
Searching for genes involved in the pathogenesis of primary immunodeficiency diseases: lessons from mouse knockouts
C M Kokron, F A Bonilla, H C Oettgen, N Ramesh, R S Geha, F Pandolfi |
Journal of Clinical Immunology | 1997 |
Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice
A Oshiba, E Hamelmann, K Takeda, KL Bradley, JE Loader, GL Larsen, EW Gelfand |
Journal of Clinical Investigation | 1996 |
Allergic conjunctivitis and dry eye
H Fujishima, I Toda, J Shimazaki, K Tsubota |
The British journal of ophthalmology | 1996 |
Allergen-specific IgG1 and IgG3 through Fc gamma RII induce eosinophil degranulation
M Kaneko, MC Swanson, GJ Gleich, H Kita |
Journal of Clinical Investigation | 1995 |