JCI - Citations to Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia.

Citations to this article

Megakaryocyte growth and development factor. Analyses of in vitro effects on human megakaryopoiesis and endogenous serum levels during chemotherapy-induced thrombocytopenia.

J L Nichol, … , E Choi, J Bogenberger

J L Nichol, … , E Choi, J Bogenberger

Published June 1, 1995
Citation Information: J Clin Invest. 1995;95(6):2973-2978. https://doi.org/10.1172/JCI118005.

View: Text | PDF

Research Article

Total citations by year

Year:	2020	2018	2015	2014	2013	2010	2009	2008	2007	2006	2004	2003	2002	2001	2000	1999	1998	1997	1996	1995	Total
Citations:	1	1	1	2	1	2	1	2	1	1	7	2	4	5	15	17	32	17	14	2	128

Citation information

Citations to this article (128)

Title and authors	Publication	Year
Development and characterization of a novel, megakaryocyte NF‐κB reporter cell line for investigating inflammatory responses TM Vallance, JJ Sheard, Y Meng, EC Torre, K Patel, D Widera, S Vaiyapuri	Journal of Thrombosis and Haemostasis	2020
GPIbα is required for platelet-mediated hepatic thrombopoietin generation M Xu, J Li, MA Neves, G Zhu, N Carrim, R Yu, S Gupta, J Marshall, O Rotstein, J Peng, M Hou, S Kunishima, J Ware, DR Branch, AH Lazarus, ZM Ruggeri, J Freedman, H Ni	Blood	2018
Thrombopoiesis K Kaushansky	Seminars in Hematology	2015
Thrombopoietin from beginning to end IS Hitchcock, K Kaushansky	British Journal of Haematology	2014
Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation KR Machlus, JN Thon, JE Italiano	British Journal of Haematology	2014
Thrombopoietin levels in patients with disorders of platelet production: Diagnostic potential and utility in predicting response to TPO Receptor agonists RS Makar, OS Zhukov, MA Sahud, DJ Kuter	American Journal of Hematology	2013
Thrombopoietic agents R Stasi, J Bosworth, E Rhodes, MS Shannon, F Willis, EC Gordon-Smith	Blood Reviews	2010
A biomathematical model of human thrombopoiesis under chemotherapy M Scholz, A Gross, M Loeffler	Journal of Theoretical Biology	2010
PEGylated Protein Drugs: Basic Science and Clinical Applications FM Veronese		2009
Emerging treatments for thrombocytopenia: Increasing platelet production K Peeters, JM Stassen, D Collen, CV Geet, K Freson	Drug Discovery Today	2008
Biopharmaceutical Drug Design and Development S Wu-Pong, Y Rojanasakul		2008
Historical review: megakaryopoiesis and thrombopoiesis K Kaushansky	Blood	2007
AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP JB Bussel, DJ Kuter, JN George, R McMillan, LM Aledort, GT Conklin, AE Lichtin, RM Lyons, J Nieva, JS Wasser, I Wiznitzer, R Kelly, CF Chen, JL Nichol	New England Journal of Medicine	2006
Prospective screening of 205 patients with ITP, including diagnosis, serological markers, and the relationship between platelet counts, endogenous thrombopoietin, and circulating antithrombopoietin antibodies LM Aledort, CP Hayward, MG Chen, JL Nichol, J Bussel	American Journal of Hematology	2004
Sepsis severity is the major determinant of circulating thrombopoietin levels in septic patients SG Zakynthinos, S Papanikolaou, T Theodoridis, EG Zakynthinos, V Christopoulou-Kokkinou, G Katsaris, AC Mavrommatis	Critical Care Medicine	2004
Proportion of Megakaryocyte Progenitors in Cord Blood Correlates with Platelet Recovery after Cord Blood Transplant H IKEDA, K ISOYAMA, H SASAKI, D TOYAMA, S YAMAMOTO, Y ARITA, I HOSAKI, Y HIROTA, K YAMADA, H NISHIHIRA	The Showa University Journal of Medical Sciences	2004
Thrombocytosis: a paraneoplastic syndrome in patients with hepatocellular carcinoma Shinn-Jang Hwang, Jiing-Chyuan Luo, Chung-Pin Li, Cheng-Wei Chu, Jaw-Ching Wu, Chiung-Ru Lai, Jen-Huei Chiang, Gar-Yang Chau, Wing-Yiu Lui, Chun-Chung Lee, Full-Young Chang, Shou-Dong Lee	World journal of gastroenterology : WJG	2004
Thrombocytosis: A paraneoplastic syndrome in patients with hepatocellular carcinoma SJ Hwang	World journal of gastroenterology : WJG	2004
Hematopoietic Growth Factors in Oncology G Morstyn, MA Foote, GJ Lieschke		2004
Induction of megakaryocytopoiesis and thrombocytopoiesis by JTZ-132, a novel small molecule with thrombopoietin mimetic activities K Inagaki, T Oda, Y Naka, H Shinkai, N Komatsu, H Iwamura	Blood	2004
Etiology of the myeloproliferative disorders: the role of thrombopoietin K Kaushansky	Seminars in Hematology	2003
Differential maturation of megakaryocyte progenitor cells from cord blood and mobilized peripheral blood LF Schipper, A Brand, N Reniers, CJ Melief, R Willemze, WE Fibbe	Experimental Hematology	2003
Human plasma thrombopoietin levels are regulated by binding to platelet thrombopoietin receptors in vivo S Scheding, M Bergmann, A Shimosaka, P Wolff, C Driessen, G Rathke, K Jaschonek, W Brugger, L Kanz	Transfusion	2002
Human megakaryocytes cultured in vitro accumulate serotonin but not meta-iodobenzylguanidine whereas platelets concentrate both GA Tytgat, MD Brug, PA Voûte, LA Smets, M Rutgers	Experimental Hematology	2002
Pharmacodynamic Modeling of Thrombopoietin, Platelet, and Megakaryocyte Dynamics in Patients with Acute Myeloid Leukemia Undergoing Dose Intensive Chemotherapy SH Bernstein, WJ Jusko, W Krzyzanski, J Nichol, M Wetzler	The Journal of Clinical Pharmacology	2002
Serum thrombopoietin levels and anti-thrombopoietin antibodies in systemic lupus erythematosus W Füreder, U Firbas, JL Nichol, J Pistillo, S Winkler, H Hiesberger, WR Sperr, J Smolen, G Schett	Lupus	2002
Comparison of megakaryopoiesis in vitro of paired peripheral blood progenitor cells and bone marrow harvested during remission in patients with acute myeloid leukaemia M Briggs, JA Adams, ML Brereton, R Burgess, K Hyde, H Lenehan, JA Yin	British Journal of Haematology	2001
Analysis of the kinetics of TPOuptake during platelet transfusion CC Folman, SM de Jong, M Haas, AE von Borne	Transfusion	2001
Hydroxyurea-associated Platelet Count Oscillations in Polycythemia Vera: A Report of Four New Cases and a Review DP Steensma, CN Harrison, A Tefferi	Leukemia & Lymphoma	2001
KINETIC ANALYSIS OF MEGAKARYOPOIESIS INDUCED BY RECOMBINANT HUMAN INTERLEUKIN 11 IN MYELOSUPPRESSED MICE M Saitoh	Cytokine	2001
Kinetics of CFU-Mk after automated plateletpheresis T Wagner, DW Schwartz, M Winter, E Kabrna, M Kollars, I Schwarzinger, G Lanzer, WR Mayr, K Geissler	Vox Sanguinis	2001
Thrombopoietin Is Synergistic with Other Cytokines for Expansion of Cord Blood Progenitor Cells JH Won, SD Cho, SK Park, GT Lee, SH Baick, WS Suh, DS Hong, HS Park	Journal of Hematotherapy & Stem Cell Research	2000
Hepatocyte growth factor/scatter factor enhances the thrombopoietin mRNA expression in rat hepatocytes and cirrhotic rat livers K Yamashita, H Matsuoka, T Ochiai, R Matsushita, Y Kubuki, M Suzuki, H Tsubouchi	Journal of Gastroenterology and Hepatology	2000
Technical Aspects and Clinical Impact of Hematopoietic Progenitor Subset Quantification J Baech, HE Johnsen	Stem Cells	2000
Thrombopoietin Levels in Patients Undergoing Autologous Peripheral Blood Stem Cell Transplantation C Yoshimura, S Nomura, K Katsura, K Yamaguchi, S Fukuhara	Vox Sanguinis	2000
CFU-Mk Content of Immunoselected CD34+ Peripheral Blood Progenitor Cells, Evaluated with an Adapted Serum-Free Methylcellulose Assay, Is Predictive of Platelet Lineage Reconstitution in Children with Solid Tumors N Boiret, J Kanold, M Fouassier, JM Bons, P Halle, C Rapatel, J Berger, P Pireyre, V Blanzat, P Travade, J Bonhomme, F Demeocq, MG Berger	Journal of Hematotherapy & Stem Cell Research	2000
Stressful delivery influences circulating thrombopoietin (TPO) levels in newborns: possible role for cortisol in TPO-mpl binding K Ikeno, K Koike, A Takeshita, K Shinjo, T Higuchi, T Nakabayashi, S Akanuma, K Hizume, A Ishiguro, K Ogami, T Kato, H Miyazaki, R Ohno, A Komiyama	Early Human Development	2000
Pharmacokinetic Analysis of Pegylated Megakaryocyte Growth and Development Factor in Humans RH de Boer, LK Roskos, E Cheung, S Fox, RL Basser, J Marty, CG Begley, J Cebon	Growth Factors	2000
Use of PEG-rHuMGDF in platelet engraftment after autologous stem cell transplantation KK Fields, M Crump, I Bence-Bruckler, S Bernstein, S Williams, S Frankel, A Miller, G Demetri, JM Nabholtz, S Cruickshank, M Lill	Bone Marrow Transplantation	2000
Thrombopoietic cytokines in relation to platelet recovery after bone marrow transplantation DJ Weisdorf, T DeFor, J Nichol, A Panoskaltsis-Mortari, BR Blazar	Bone Marrow Transplantation	2000
The frequency and proliferative potential of megakaryocytic colony-forming cells (Meg-CFC) in cord blood, cytokine-mobilized peripheral blood and bone marrow and their correlation with total CFC numbers: implications for the quantitation of Meg-CFC to predict platelet engraftment following cord blood transplantation A Drygalski, G Xu, D Constantinescu, I Kashiwakura, T Farley, L Dobrila, P Rubinstein, JW Adamson	Bone Marrow Transplantation	2000
Flow cytometric detection of growth factor receptors in autografts and analysis of growth factor concentrations in autologous stem cell transplantation: possible significance for platelet recovery I Schiødt, CH Jensen, E Kjærsgaard, E Gaarsdal, K Nikolajsen, HE Johnsen	Bone Marrow Transplantation	2000
Defective Megakaryocytic Development in Myelodysplastic Syndromes WK Hofmann, U Kalina, S Koschmieder, G Seipelt, D Hoelzer, OG Ottmann	Leukemia & Lymphoma	2000
THROMBOCYTOPENIA IN LIVER TRANSPLANT RECIPIENTS: Predictors, Impact on Fungal Infections, and Role of Endogenous Thrombopoietin FY Chang, N Singh, T Gayowski, MM Wagener, SM Mietzner, JE Stout, IR Marino	Transplantation	2000
Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers LA Harker, LK Roskos, UM Marzec, RA Carter, JK Cherry, B Sundell, EN Cheung, D Terry, W Sheridan	Blood	2000
Hypersensitivity of circulating progenitor cells to megakaryocyte growth and development factor (PEG-rHu MGDF) in essential thrombocythemia AA Axelrad, D Eskinazi, PN Correa, D Amato	Blood	2000
Physiology and clinical applications of platelet growth factors LA Harker	Current Opinion in Hematology	1999
Serum thrombopoietin and erythropoietin levels in patients with acute promyelocytic leukaemia during all-trans retinoic acid treatment K Kinjo, M Kizaki, N Takayama, N Michikawa, A Oda, SI Okamoto, T Tahara, T Kato, H Miyazaki, Y Ikeda	British Journal of Haematology	1999
Thrombopoietin concentrations are low in patients with cirrhosis and thrombocytopenia and are restored after orthotopic liver transplantation J Goulis, TN Chau, S Jordan, AB Mehta, A Watkinson, K Rolles, AK Burroughs	Gut	1999
A Case of Thrombopoietin-Producing Ovarian Carcinoma Confirmed by Immunohistochemistry M Furuhashi, Y Miyabe, H Oda	Gynecologic Oncology	1999
Relationship between megakaryocyte mass and serum thrombopoietin levels as revealed by a case of cyclic amegakaryocytic thrombocytopenic purpura CS Zent, J Ratajczak, MZ Ratajczak, J Anastasi, PC Hoffman, AM Gewirtz	British Journal of Haematology	1999
The in vitro effect of pegylated recombinant human megakaryocyte growth and development factor (PEGrHuMGDF) on megakaryopoiesis in patients with aplastic anaemia ML Brereton, JA Adams, M Briggs, JA Yin	British Journal of Haematology	1999
Endogenous thrombopoietin serum levels during multicycle chemotherapy C Engel, M Loeffler, H Franke, S Schmitz	British Journal of Haematology	1999
Age-related changes in thrombopoietin in children: reference interval for serum thrombopoietin levels A Ishiguro, T Nakahata, K Matsubara, Y Hayashi, T Kato, Y Suzuki, T Shimbo	British Journal of Haematology	1999
Interaction of thrombopoietin with the platelet c-mpl receptor in plasma: binding, internalization, stability and pharmacokinetics J Li, Y Xia, DJ Kuter	British Journal of Haematology	1999
A combination of megakaryocyte growth and development factor and interleukin-1 is sufficient to culture large numbers of megakaryocytic progenitors and megakaryocytes for transfusion purposes S Oudenrijn, M Haas, J Calafat, CE van der Schoot, AE von Borne	British Journal of Haematology	1999
Thrombopoietin and the c-Mpl receptor: insights from gene targeting WS Alexander	The International Journal of Biochemistry & Cell Biology	1999
Elevated Serum Thrombopoietin and Interleukin-6 Concentrations in Thrombocytosis Associated with Inflammatory Bowel Disease F Heits, M Stahl, D Ludwig, EF Stange, W Jelkmann	Journal of Interferon & Cytokine Research	1999
Immature megakaryocytes undergo apoptosis in the absence of thrombopoietin M Osada, T Komeno, K Todokoro, M Takizawa, H Kojima, K Suzukawa, H Ninomiya, T Abe, T Nagasawa	Experimental Hematology	1999
A Role for Changes in Platelet Production in the Cause of Acute Coronary Syndromes B van der Loo, JF Martin	Arteriosclerosis, thrombosis, and vascular biology	1999
Advances in Allogeneic Hematopoietic Stem Cell Transplantation RK Burt, MM Brush		1999
Ex Vivo Cultured Megakaryocytes Express Functional Glycoprotein IIb-IIIa Receptors and Are Capable of Adenovirus-Mediated Transgene Expression N Faraday, JJ Rade, DC Johns, G Khetawat, SJ Noga, JF DiPersio, Y Jin, JL Nichol, JS Haug, PF Bray	Blood	1999
A Randomized, Double-Blind, Placebo-Controlled Study With Pegylated Recombinant Human Megakaryocyte Growth and Development Factor (PEG-rHuMGDF) as an Adjunct to Chemotherapy for Adults With De Novo Acute Myeloid Leukemia E Archimbaud, OG Ottmann, JA Yin, K Lechner, H Dombret, MA Sanz, G Heil, P Fenaux, W Brugger, A Barge, C OBrien-Ewen, J Matcham, D Hoelzer	Blood	1999
Thrombopoietin Level in Young Patients Is Related to Megakaryocyte Frequency and Platelet Count MU Kuefer, WC Wang, DR Head, JA Wilimas, WL Furman, Q Liu, AC Hornkohl, DM Best, CW Jackson	Journal of Pediatric Hematology/Oncology	1998
Effects of mpl ligands on platelet production and function in nonhuman primates LA Harker, UM Marzec, AB Kelly	Stem Cells	1998
Cytokines in Hematopoiesis WS Alexander	International Reviews of Immunology	1998
The Molecular Control of Hematopoiesis: Progress and Problems with Gene Manipulation D Metcalf	Stem Cells	1998
The combined administration of daniplestim and mpl ligand augments the hematopoietic reconstitution observed with single cytokine administration in a nonhuman primate model of myelosuppression AM Farese, TJ Macvittie, LB Lind, WG Smith, JP Mckearn	Stem Cells	1998
Unilineage hematopoietic differentiation in bulk and single cell culture B Ziegler, U Testa, L Vitelli, M Valtieri, C Peschle, G Condorelli	Stem Cells	1998
The Mpl ligand and platelet homeostasis JL Nichol	Acta Paediatrica	1998
Overview of the safety and biologic effects of peg&hyphen;rhumgdf in clinical trials W Sheridan, D Menchaca	Stem Cells	1998
Thrombopoietin level is inversely related to blast count, not platelet number, in Down syndrome neonates with transient myeloproliferative disorder M Bonno, E Azuma, H Kawasaki, XL Zhang, Y Komada, M Hirayama, M Higashigawa, M Umemoto, T Koike, T Kato, T Tahara, H Miyazaki, M Sakurai	American Journal of Hematology	1998
Interferon-γ and Human Megakaryopoiesis K Tsuji, K Muraoka, T Nakahata	Leukemia & Lymphoma	1998
Neutralization of Biological Activity and Inhibition of Receptor Binding by Antibodies Against Human Thrombopoietin T Tahara, T Kuwaki, A Matsumoto, H Morita, H Watarai, Y Inagaki, H Ohashi, K Ogami, H Miyazaki, T Kato	Stem Cells	1998
Early australian clinical studies with pegylated recombinant human megakaryocyte growth and development factor RL Basser	Stem Cells	1998
Endogenous TPO (eTPO) levels in health and disease: Possible clues for therapeutic intervention JL Nichol	Stem Cells	1998
Thrombopoietic factors potentially useful in the treatment of acute leukemia E Archimbaud, X Thomas	Leukemia Research	1998
Therapeutic Cytokine Stimulation of Thrombocytopoiesis LA Harker	Transfusion Science	1998
10 Thrombopoietin and its receptor: structure, function and role in the regulation of platelet production AE von Borne, C Folman, GE Linthorst, L Porcelijn, S Oudenrijn, E der Schoot, M Haas	Baillière's Clinical Haematology	1998
11 Thrombopoietin: its role in platelet disorders and as a new drug in clinical medicine AE von Borne, C Folman, GE Linthorst, L Porcelijn, S Oudenrijn, E der Schoot, M Haas	Baillière's Clinical Haematology	1998
Quantitative analysis of thrombopoietin receptors on human megakaryocytes T Kuwaki, T Hagiwara, C Yuki, I Kodama, T Kato, H Miyazaki	FEBS Letters	1998
Expression and Function of the Megakaryocyte Growth and Development Factor Receptor in Acute Myeloid Leukemia Blasts M Wetzler, SH Bernstein, H Baumann, KM Fries, C Stewart, L Blumenson, MR Baera, GP Herziga, CD Bloomfielda, JL Slack	Leukemia & Lymphoma	1998
Thrombocytopenia—Platelet Support or Growth Factors? R Manley, MF Murphy	Hematology	1998
Interferon-induced thrombocytopenia: Is it time for thrombopoietin? TG Martin, MA Shuman	Hepatology	1998
The Effect of Hematopoietic Growth Factors on Platelet Aggregability A Kaplan, S Kaplan, KF Marcoe, LR Sauvage, WP Hammond	Clinical and Applied Thrombosis/Hemostasis	1998
Megakaryocyte progenitors derived from bone marrow or G-CSF-mobilized peripheral blood CD34+ cells show a distinct phenotype and responsiveness to interleukin-3 (IL-3) and PEG-recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) L Catani, L Gugliotta, E Campanini, S Mangianti, D Gibellini, S Baravelli, N Vianelli, RM Lemoli, S Tura	British Journal of Haematology	1998
Blunted thrombopoietin response to interferon alfa-induced thrombocytopenia during treatment for hepatitis C M Peck-Radosavljevic, M Wichlas, J Pidlich, P Sims, G Meng, J Zacherl, S Garg, C Datz, A Gangl, P Ferenci	Hepatology	1998
Acute Leukemias VII W Hiddemann, T Büchner, B Wörmann, J Ritter, U Creutzig, M Keating, W Plunkett		1998
Cyclical Neutropenia and Other Periodic Hematological Disorders: A Review of Mechanisms and Mathematical Models C Haurie, DC Dale, MC Mackey	Blood	1998
Ineffective Platelet Production in Thrombocytopenic Human Immunodeficiency Virus–Infected Patients JL Cole, UM Marzec, CJ Gunthel, S Karpatkin, L Worford, IB Sundell, JL Lennox, JL Nichol, LA Harker	Blood	1998
Treatment of Thrombocytopenia in Chimpanzees Infected With Human Immunodeficiency Virus by Pegylated Recombinant Human Megakaryocyte Growth and Development Factor LA Harker, UM Marzec, F Novembre, IB Sundell, EK Waller, S Karpatkin, HM McClure, AB Kelly, RB Stead	Blood	1998
c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors With Overlapping Yet Distinct Activities SD Lyman, SE Jacobsen	Blood	1998
Multilineage Hematopoietic Recovery by a Single Injection of Pegylated Recombinant Human Megakaryocyte Growth and Development Factor in Myelosuppressed Mice K Shibuya, H Akahori, K Takahashi, E Tahara, T Kato, H Miyazaki	Blood	1998
Effects of Cytokines on Platelet Production From Blood and Marrow CD34+ Cells F Norol, N Vitrat, E Cramer, J Guichard, SA Burstein, W Vainchenker, N Debili	Blood	1998
Interactions of Erythropoietin, Granulocyte Colony-Stimulating Factor, Stem Cell Factor, and Interleukin-11 on Murine Hematopoiesis During Simultaneous Administration I Roeder, G de Haan, C Engel, W Nijhof, B Dontje, M Loeffler	Blood	1998
Regulation of polymorphonuclear cell activation by thrombopoietin MF Brizzi, E Battaglia, A Rosso, P Strippoli, G Montrucchio, G Camussi, L Pegoraro	Journal of Clinical Investigation	1997
Effect of Recombinant Interleukin-6 and Thrombopoietin on Isolated Guinea Pig Bone Marrow Megakaryocyte Protein Phosphorylation and Proplatelet Formation RM Leven, B Clark, F Tablin	Blood Cells, Molecules, and Diseases	1997
The impact of thrombopoietin and related Mpl-Ligands on transfusion medicine AM Farese, CA Schiffer, TJ MacVittie	Transfusion Medicine Reviews	1997
THROMBOPOIETIN: UNDERSTANDING AND MANIPULATING PLATELET PRODUCTION KK MD	Annual Review of Medicine	1997
Thrombopoietin K Kaushansky	Trends in Endocrinology & Metabolism	1997
1 The evolution of megakaryocytes to platelets P Nurden, C Poujol, AT Nurden	Baillière's Clinical Haematology	1997
Serum thrombopoietin and interleukin 6 concentrations in tumour patients and response to chemotherapy-induced thrombocytopenia F Heits, DM Katschinski, U Wilmsen, GJ Wiedemann, W Jelkmann	European Journal of Haematology	1997
Effects of Polyethylene Glycol–Conjugated Recombinant Human Megakaryocyte Growth and Development Factor on Platelet Counts after Chemotherapy for Lung Cancer M Fanucchi, J Glaspy, J Crawford, J Garst, R Figlin, W Sheridan, D Menchaca, D Tomita, H Ozer, L Harker	New England Journal of Medicine	1997
Is inadequate thrombopoietin production a major cause of thrombocytopenia in cirrhosis of the liver? M Peck-Radosavljevic, J Zacherl, YG Meng, J Pidlich, E Lipinski, F Längle, R Steininger, F Mühlbacher, A Gangl	Journal of Hepatology	1997
Cytokines, platelet production and hemostasis SA Burstein	Platelets	1997
Thrombopoiesis and Thrombopoietins DJ Kuter, P Hunt, W Sheridan, D Zucker-Franklin		1997
Prevention of Thrombocytopenia and Neutropenia in a Nonhuman Primate Model of Marrow Suppressive Chemotherapy by Combining Pegylated Recombinant Human Megakaryocyte Growth and Development Factor and Recombinant Human Granulocyte Colony-Stimulating Factor LA Harker, UM Marzec, AB Kelly, E Cheung, A Tomer, JL Nichol, SR Hanson, RB Stead	Blood	1997
A Single Injection of Pegylated Murine Megakaryocyte Growth and Development Factor (MGDF ) Into Mice Is Sufficient to Produce a Profound Stimulation of Megakaryocyte Frequency, Size, and Ploidization JT Arnold, NC Daw, PE Stenberg, D Jayawardene, DK Srivastava, CW Jackson	Blood	1997
Human Platelets as a Model for the Binding and Degradation of Thrombopoietin PJ Fielder, P Hass, M Nagel, E Stefanich, R Widmer, GL Bennett, GA Keller, FJ de Sauvage, D Eaton	Blood	1997
Human Platelets Display High-Affinity Receptors for Thrombopoietin VC Broudy, NL Lin, DF Sabath, T Papayannopoulou, K Kaushansky	Blood	1997
Thrombopoietin in Patients With Congenital Thrombocytopenia and Absent Radii: Elevated Serum Levels, Normal Receptor Expression, But Defective Reactivity to Thrombopoietin M Ballmaier, H Schulze, G Strauβ, K Cherkaoui, N Wittner, S Lynen, S Wolters, J Bogenberger, K Welte	Blood	1997
Megakaryocyte Growth and Development Factor: A Review of Early Clinical Studies R Abraham, RL Basser	The oncologist	1997
Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia AM Farese, P Hunt, LB Grab, TJ MacVittie	Journal of Clinical Investigation	1996
Thrombopoietin and platelet development K Kaushansky	The Western journal of medicine	1996
Dissecting Megakaryocytopoiesis in Vivo with Toxigenes G Marguerie, V Roullot, DT Roux	Stem Cells	1996
Protein Characteristics of Thrombopoietin T Kato	Stem Cells	1996
The Role of Platelet Growth Factors in Cancer Therapy K Clarke, RL Basser	Stem Cells	1996
Cytokines at the research-clinical interface: potential applications TL Holyoake	Blood Reviews	1996
In Vivo Biological Effects of Various Forms of Thrombopoietin in a Murine Model of Transient Pancytopenia GR Thomas, H Thibodeaux, CJ Errett, J Mathias, M Marian, G Meng, RL Vandlen, DL Eaton	Stem Cells	1996
Preclinical Biology of Megakaryocyte Growth and Development Factor: A Summary JL Nichol	Stem Cells	1996
Physiologic Role of TPO in Thrombopoiesis H Miyazaki	Stem Cells	1996
Mechanism of Thrombocytosis in Hepatoblastoma: A Case Report H Yamaguchi, E Ishii, Y Hayashida, Y Hirata, R Sakai, S Miyazaki	Pediatric Hematology-Oncology	1996
Effects of Pegylated Recombinant Human Megakaryocyte Growth and Development Factor on Thrombocytopenia Induced by a New Myelosuppressive Chemotherapy Regimen in Mice H Akahori, K Shibuya, M Ozai, M Ida, K Kabaya, T Kato, H Miyazaki	Stem Cells	1996
In Vivo Effects of Pegylated Recombinant Human Megakaryocyte Growth and Development Factor on Hematopoiesis in Normal Mice K Kabaya, H Akahori, K Shibuya, Y Nitta, M Ida, M Kusaka, T Kato, H Miyazaki	Stem Cells	1996
Megakaryocytes K Kaushansky	Trends in Cardiovascular Medicine	1996
Thrombopoietin: Biology and Clinical Applications DJ Kuter	The oncologist	1996
The physiologic role and therapeutic potential of the Mpl&hyphen;ligand in thrombopoiesis P Hunt	Stem Cells	1995
The new generation of recombinant human hematopoietic cytokines P Hunt, MA Foote	Current Opinion in Biotechnology	1995

Advertisement