Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Angiotensinogen as a risk factor for essential hypertension in Japan.
A Hata, … , K Tamura, J M Lalouel
A Hata, … , K Tamura, J M Lalouel
Published March 1, 1994
Citation Information: J Clin Invest. 1994;93(3):1285-1287. https://doi.org/10.1172/JCI117083.
View: Text | PDF
Research Article Article has an altmetric score of 3

Angiotensinogen as a risk factor for essential hypertension in Japan.

  • Text
  • PDF
Abstract

A common molecular variant of angiotensinogen (AGT), the precursor of the potent vasoactive hormone angiotensin II, has been incriminated as a marker for a genetic predisposition to essential hypertension in Caucasians (Jeunemaitre, X., F. Soubrier, Y. V. Kotelevtsev, R. P. Lifton, C. S. Williams, A. Charru, S. C. Hunt, P. N. Hopkins, R. R. Williams, J. M. Lalouel, and P. Corvol. 1992. Cell. 71:169-180). We now show that the same variant, T235, is associated with essential hypertension in Japanese patients. The observation of this association in a distinct, ethnically homogeneous population further substantiates an involvement of angiotensinogen in the pathogenesis of essential hypertension and has physiological, epidemiological, and evolutionary implications.

Authors

A Hata, C Namikawa, M Sasaki, K Sato, T Nakamura, K Tamura, J M Lalouel

×

Total citations by year

Year: 2023 2021 2020 2019 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1988 Total
Citations: 1 1 1 1 2 2 3 5 3 6 1 2 3 3 5 4 11 3 10 8 10 25 12 24 17 16 3 1 183
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (183)

Title and authors Publication Year
Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican Population.
Isordia-Salas I, Santiago-Germán D, Flores-Arizmendi A, Leaños-Miranda A
Journal of the renin-angiotensin-aldosterone system : JRAAS 2023
Hypertension genetics past, present and future applications
KJ Olczak, V TaylorBateman, HL Nicholls, M Traylor, CP Cabrera, PB Munroe
Journal of Internal Medicine 2021
Dose-Dependent Effect of Angiotensin II on Uterine Smooth Muscle Motility
RM Barbu, G Butura, I Armasu, B Stana, CM Gavrilescu, W Bild
2020
Genetics and ESKD Disparities in African Americans
EM Umeukeje, BA Young
American journal of kidney diseases : the official journal of the National Kidney Foundation 2019
The burden of major adverse cardiac events in patients with coronary artery disease
IT Tsai, CP Wang, YC Lu, WC Hung, CC Wu, LF Lu, FM Chung, CC Hsu, YJ Lee, TH Yu
BMC Cardiovascular Disorders 2017
RAS Genetic Variants in Interaction with ACE Inhibitors Drugs Influences Essential Hypertension Control
F Heidari, R Vasudevan, SZ Ali, P Ismail, M Arkani
Archives of Medical Research 2017
Evolutionary and genetic roots of hypertensive disease
AL Markel
Russian Journal of Genetics 2015
Angiotensinogen (AGT) M235T, AGT T174M and Angiotensin-1- Converting Enzyme (ACE) I/D Gene Polymorphisms in Essential Hypertension: Effects on Ramipril Efficacy
V Kolovou, E Lagou, C Mihas, G Vasiliki, N Katsiki, A Kollia, F Triposkiadis, D Degiannis, S Mavrogeni, G Kolovou
The open cardiovascular medicine journal 2015
Comprehensive Physiology
SN Cheuvront, RW Kenefick
Comprehensive Physiology 2014
The role of the kidney and the sympathetic nervous system in hypertension
P Thomas, I Dasgupta
Pediatric Nephrology 2014
A polymorphism in AGT and AGTR1 gene is associated with lead-related high blood pressure
HK Kim, H Lee, JT Kwon, HJ Kim
Journal of Renin-Angiotensin-Aldosterone System 2014
The confounding effect of cryptic relatedness for environmental risks of systolic blood pressure on cohort studies
K Shibata, A Hozawa, G Tamiya, M Ueki, T Nakamura, H Narimatsu, I Kubota, Y Ueno, T Kato, H Yamashita, A Fukao, T Kayama
Molecular Genetics & Genomic Medicine 2013
Hypertension-susceptibility gene prevalence in the Pacific Islands and associations with hypertension in Melanesia
T Furusawa, I Naka, T Yamauchi, K Natsuhara, R Eddie, R Kimura, M Nakazawa, T Ishida, T Inaoka, Y Matsumura, Y Ataka, R Ohtsuka, J Ohashi
Journal of Human Genetics 2013
Emery and Rimoin's Principles and Practice of Medical Genetics
DC Wallace, MT Lott, V Procaccio
Emery and Rimoin's Principles and Practice of Medical Genetics 2013
Association between the Angiotensinogen (AGT) gene (M235T) polymorphism and Essential Hypertension in Egyptian patients
MM Shamaa, H Fouad, M Haroun, M Hassanein, MA Hay
The Egyptian Heart Journal 2013
Genetics of Human Hypertension, the Role of Angiotensinogen. Should It be One of the Drug Target Genes?
GD Kolovou, S Mavrogeni
Angiology 2013
A study of the M235T variant of the angiotensinogen gene and hypertension in a sample population of Calabar and Uyo, Nigeria
ME Kooffreh, CI Anumudu, EE Akpan, EV Ikpeme, PL Kumar
Egyptian Journal of Medical Human Genetics 2012
GENETIC AND ENVIRONMENTAL INFLUENCES ON BLOOD PRESSURE IN AN URBAN INDIAN POPULATION
S Gupta, S Kapoor
Journal of Biosocial Science 2012
Estimation of risk and interaction of single nucleotide polymorphisms at angiotensinogen locus causing susceptibility to essential hypertension: a case control study
B Charita, G Padma, P Sushma, P Deepak, T Padma
Journal of Renin-Angiotensin-Aldosterone System 2012
Association Between the M268T Polymorphism in the Angiotensinogen Gene and Essential Hypertension in a South Indian Population
MG Chand, J Srinath, RS Rao, BV Lakkakula, S Kumar, VR Rao
Biochemical Genetics 2011
The Impact of Hypertension on Patients with Acute Coronary Syndromes
C Picariello, C Lazzeri, P Attanà, M Chiostri, GF Gensini, S Valente
International Journal of Hypertension 2011
The M235T polymorphism of the angiotensinogen gene in South Indian patients of hypertrophic cardiomyopathy
PP Rao, A Munshi, R Mullapudi, PS Kumar, A Sharath, GA Krishna, M Sadhnani
Journal of Renin-Angiotensin-Aldosterone System 2011
Do genetic variations alter the effects of exercise training on cardiovascular disease and can we identify the candidate variants now or in the future?
JM Hagberg
Journal of applied physiology 2011
The Associations Between Maternal and Fetal Angiotensinogen M235T Polymorphism and Pregnancy-Induced Hypertension in Chinese Women
P Xiang, Z Li, H Di, S Nie, W Yan
Reproductive sciences (Thousand Oaks, Calif.) 2011
Exercise Genomics
LS Pescatello, SM Roth
2011
Genetic and Molecular Aspects of Sport Performance
MA Tarnopolsky
Genetic and Molecular Aspects of Sport Performance 2010
Angiotensinogen T174M and M235T Variants and Hypertension in the Hani and Yi Minority Groups of China
J Yuan, W Tang, Y Chun, H Ying, Y Yang, C Xiao
Biochemical Genetics 2009
Cardiovascular Endocrinology
VA Fonseca
Cardiovascular Endocrinology 2009
Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure
M Zakrzewski-Jakubiak, S Denus, MP Dubé, F Bélanger, M White, J Turgeon
British Journal of Clinical Pharmacology 2008
Candidate gene polymorphisms and their association with hypertension in Malays
DM Ghazali, A Rehman, AR Rahman
Clinica Chimica Acta 2008
Association of renin-angiotensin system and natriuretic peptide receptor A gene polymorphisms with hypertension in a Hellenic population
A Tsezou, G Karayannis, E Giannatou, V Papanikolaou, F Triposkiadis
Journal of Renin-Angiotensin-Aldosterone System 2008
Genetics of arterial hypertension and hypotension
D Rosskopf, M Schürks, C Rimmbach, R Schäfers
Naunyn-Schmiedeberg's Archives of Pharmacology 2007
A review of the genetics of essential hypertension
A Binder
Current Opinion in Cardiology 2007
Angiotensinogen Gene Variation and Hypertension in a Cohort Study in Japanese
Kishimoto T, Suyama A, Igarashi A, Osaki Y, Okamoto M, Yamamoto T, Nanba E, Kurosawa Y, Fukumoto S
Journal of Epidemiology 2007
The genetic dissection of essential hypertension
AW Cowley
Nature Reviews Genetics 2006
Renin-angiotensin system genes and exercise training-induced changes in sodium excretion in African American hypertensives
JM Jones, JJ Park, J Johnson, D Vizcaino, B Hand, R Ferrell, M Weir, T Dowling, T Obisesan, M Brown
Ethnicity & disease 2006
Evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischaemic stroke
N Tuncer, S Tuglular, G Kılıç, A Sazcı, Ö Us, İ Kara
Journal of Clinical Neuroscience 2006
Angiotensinogen gene polymorphism (Met235Thr) influences visceral obesity and insulin resistance in obese Japanese women
Y Takakura, T Yoshida, K Yoshioka, T Umekawa, A Kogure, H Toda, K Kagawa, S Fukui, T Yoshikawa
Metabolism 2006
Single-Nucleotide Polymorphisms for Diagnosis of Salt-Sensitive Hypertension
H Sanada, J Yatabe, S Midorikawa, S Hashimoto, T Watanabe, JH Moore, MD Ritchie, SM Williams, JC Pezzullo, M Sasaki, GM Eisner, PA Jose, RA Felder
Clinical chemistry 2006
Genetic determinants of blood pressure regulation
JB Marteau, M Zaiou, G Siest, S Visvikis-Siest
Journal of Hypertension 2005
Angiotensinogen M235T gene variants and its association with essential hypertension and plasma renin activity in Malaysian subjects: a case control study
YH Say, KH Ling, G Duraisamy, S Isaac, R Rosli
BMC Cardiovascular Disorders 2005
ACE-DD genotype is associated with the occurrence of acute coronary syndrome in postmenopausal women
J Méthot, BA Hamelin, P Bogaty, M Arsenault, S Plante, P Poirier
International Journal of Cardiology 2005
Association of Angiotensinogen Gene Polymorphisms with Essential Hypertension in African-Americans and Caucasians
D Markovic, X Tang, M Guruju, MA Levenstien, J Hoh, A Kumar, J Ott
Human Heredity 2005
The impact of renin-angiotensin system polymorphisms on physiological and pathophysiological processes in humans
JA Miller, JW Scholey
Current Opinion in Nephrology and Hypertension 2004
Sodium glomerulopathy: Tubuloglomerular feedback and renal injury in African Americans
A Aviv, NK Hollenberg, AB Weder
Kidney International 2004
Multilocus Analysis of Hypertension: A Hierarchical Approach
SM Williams, MD Ritchie, JA Phillips, E Dawson, M Prince, E Dzhura, A Willis, A Semenya, M Summar, BC White, JH Addy, J Kpodonu, LJ Wong, RA Felder, PA Jose, JH Moore
Human Heredity 2004
Angiotensinogen promoter haplotypes are associated with blood pressure in untreated hypertensives
SM Brand-Herrmann, K Köpke, F Reichenberger, K Schmidt-Petersen, T Reineke, M Paul, W Zidek, E Brand
Journal of Hypertension 2004
Encyclopedia of Medical Genomics and Proteomics
M Matsuo
Encyclopedia of Medical Genomics and Proteomics 2004
Long-term effects of quinapril with high affinity for tissue angiotensin-converting enzyme after coronary intervention in Japanese
M Otsuka, H Yamamoto, T Okimoto, Y Dohi, S Mito, Y Gomyo, T Fujii, W Matsuura, Y Hirai, N Kohno
American Heart Journal 2004
Role of two angiotensinogen polymorphisms in blood pressure variation
M Robinson, SM Williams
Journal of Human Hypertension 2004
AGT and RH blood group polymorphisms affect blood pressure and lipids in Afro-Caribbeans
MT Robinson, TW Wilson, GA Nicholson, GA Grell, C Etienne, CM Grim, D Wilson, CE Grim
Journal of Human Hypertension 2004
Angiotensin Vol. I
T Unger, BA Schölkens
2004
Cardiovascular Pharmacogenetics
MR Wilkins
2004
A1166C variant of angiotensin II type 1 receptor gene is associated with severe hypertension in pregnancy independently of T235 variant of angiotensinogen gene
Kobashi, A Hata, K Ohta, H Yamada, EH Kato, H Minakami, S Fujimoto, K Kondo
Journal of Human Genetics 2004
Coronary heart disease, hypertension, and angiotensinogen gene variants in indian opulation
KG Nair, KK Shalia, TF Ashavaid, JJ Dalal
Journal of Clinical Laboratory Analysis 2003
Linkage disequilibrium analysis of the renin-angiotensin system genes
X Zhu, RS Cooper
Current Hypertension Reports 2003
Susceptibility Genes for Hypertension and Renal Failure
BI Freedman
Journal of the American Society of Nephrology : JASN 2003
Angiotensin II receptor polymorphisms in hypertension. Pharmacogenomic considerations
B Baudin
Pharmacogenomics 2002
Influence of angiotensinogen M253T gene polymorphism and an angiotensin converting enzyme inhibitor on restenosis after percutaneous coronary intervention
M Toyofyuku, M Imazu, K Sumii, H Yamamoto, Y Hayashi, K Hiyama, N Kohno
Atherosclerosis 2002
SNPs at the 3′ End of the Angiotensinogen Gene Define Two Haplotypes Associated with the Common 235Met Variant
S Plummer, L Morgan, N Kalsheker
The American Journal of Human Genetics 2002
Evidence for Linkage and Association with Reading Disability, on 6p21.3-22
DE Kaplan, J Gayán, J Ahn, TW Won, D Pauls, RK Olson, JC DeFries, F Wood, BF Pennington, GP Page, SD Smith, JR Gruen
The American Journal of Human Genetics 2002
Kidney disease in African Americans: genetic considerations
DA Price, ED Crook
Journal of the National Medical Association 2002
Associations between angiotensinogen gene variants and left ventricular mass and function in the HyperGEN study
W Tang, RB Devereux, DC Rao, A Oberman, PN Hopkins, DW Kitzman, DK Arnett
American Heart Journal 2002
Physiological significance of two common haplotypes of human angiotensinogen using gene targeting in the mouse
B Cvetkovic, HL Keen, X Zhang, D Davis, B Yang, CD Sigmund
Physiological genomics 2002
Angiotensinogen Gene Polymorphism at −217 Affects Basal Promoter Activity and Is Associated with Hypertension in African-Americans
S Jain, X Tang, CS Narayanan, Y Agarwal, SM Peterson, CD Brown, J Ott, A Kumar
The Journal of biological chemistry 2002
Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysis
E Brand, N Chatelain, F Paillard, L Tiret, S Visvikis, M Lathrop, F Soubrier, F Demenais
European Journal of Human Genetics 2002
The genetics of human hypertension
ED Crook
Seminars in Nephrology 2002
ACE and angiotensinogen gene genotypes and left ventricular mass in athletes
F Diet, C Graf, N Mahnke, G Wassmer, HG Predel, I Palma-Hohmann, R Rost, M Bohm
European Journal of Clinical Investigation 2001
Association of Angiotensinogen Gene Polymorphism with Erythropoietin-Induced Hypertension: A Preliminary Report
S KURIYAMA, H TOMONARI, G TOKUDOME, Y KAGUCHI, H HAYASHI, H KOBAYASHI, M HORIGUCHI, M ISHIKAWA, Y HARA, T HOSOYA
Hypertension Research 2001
An Association Study of Five Genetic Loci and Left Ventricular Hypertrophy amongst Gulf Arabs
EN OBINECHE, PM FROSSARD, AM BOKHARI
Hypertension Research 2001
Polymorphisms within the angiotensinogen gene (GT-Repeat) and the risk of stroke in pediatric patients with sickle cell disease: A case-control study
DC Tang, R Prauner, W Liu, KH Kim, RP Hirsch, MC Driscoll, GP Rodgers
American Journal of Hematology 2001
Angiotensinogen Gene Promoter Haplotype and Microangiopathy-Related Cerebral Damage: Results of the Austrian Stroke Prevention Study
H Schmidt, F Fazekas, GM Kostner, CM van Duijn, R Schmidt
Stroke; a journal of cerebral circulation 2001
T+31C Polymorphism of Angiotensinogen Gene and Essential Hypertension
K Ishikawa, S Baba, T Katsuya, N Iwai, T Asai, M Fukuda, S Takiuchi, Y Fu, T Mannami, J Ogata, J Higaki, T Ogihara
Hypertension 2001
ACE Inhibitors
P DOrléans-Juste, GE Plante
2001
Angiotensinogen in Essential Hypertension: From Genetics to Nephrology
JM Lalouel, A Rohrwasser, D Terreros, T Morgan, K Ward
Journal of the American Society of Nephrology : JASN 2001
Die Rolle des Angiotensinogengens für die essentielle Hypertonie
E Brand, J Ringel, AM Sharma
Herz 2000
Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program
MA Province, E Boerwinkle, A Chakravarti, R Cooper, M Fornage, M Leppert, N Risch, K Ranade
Journal of Hypertension 2000
Angiotensinogen T174M and M235T variants, sodium intake and hypertension among non-drinking, lean Japanese men and women
H Iso, S Harada, T Shimamoto, S Sato, A Kitamura, T Sankai, T Tanigawa, M Iida, Y Komachi
Journal of Hypertension 2000
Gene polymorphism of the renin-angiotensin system associates with risk for lacunar infarction: The Ohasama study
S Takami, Y Imai, T Katsuya, T Ohkubo, I Tsuji, K Nagai, H Satoh, S Hisamichi, J Higaki, T Ogihara
American Journal of Hypertension 2000
 -adducin polymorphism in hypertensives of South African ancestry
C Barlassina, GR Norton, NJ Samani, AJ Woodwiss, GC Candy, I Radevski, L Citterio, G Bianchi, D Cusi
American Journal of Hypertension 2000
Synergistic effect of angiotensin-converting enzyme and angiotensinogen gene on cardiac hypertrophy
HS Kim, MM Lee, BH Oh, KI Kim, KH Han, SK Park, DW Sohn, KY Yoo, YB Park, YS Choi, YW Lee
International Journal of Cardiology 2000
Renin-angiotensin-aldosterone system gene polymorphisms and hypertension in Hong Kong Chinese
G N Thomas, R P Young, B Tomlinson, K S Woo, J E Sanderson, J A Critchley
Clinical and Experimental Hypertension 2000
Combinations of Variations in Multiple Genes Are Associated With Hypertension
SM Williams, JH Addy, JA Phillips, M Dai, J Kpodonu, J Afful, H Jackson, K Joseph, F Eason, MM Murray, P Epperson, A Aduonum, LJ Wong, PA Jose, RA Felder
Hypertension 2000
Appropriate Tissue- and Cell-specific Expression of a Single Copy Human Angiotensinogen Transgene Specifically Targeted Upstream of the HPRT Locus by Homologous Recombination
B Cvetkovic, B Yang, RA Williamson, CD Sigmund
The Journal of biological chemistry 2000
Catecholamines and angiotensinogen gene expression in kidney proximal tubular cells
J S Chan, T T Wang, S L Zhang, X Chen, S Carrière
Molecular and Cellular Biochemistry 2000
Ionizing radiation and genetic risks
K Sankaranarayanan, R Chakraborty, EA Boerwinkle
Mutation Research/Reviews in Mutation Research 1999
Angiotensinogen variants and human hypertension
X Jeunemaitre, AP Gimenez-Roqueplo, J Célérier, P Corvol
Current Hypertension Reports 1999
Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes
K Bengtsson, M Orho-Melander, U Lindblad, O Melander, E Bøg-Hansen, J Ranstam, L Råstam, L Groop
Journal of Hypertension 1999
Renin-Angiotensin System Component Gene Polymorphism in Japanese Bronchial Asthma Patients
H Nakahama, K Obata, T Nakajima, H Nakamura, O Kitada, M Sugita, Y Fujita, N Kawada, T Moriyama
Journal of Asthma 1999
Primordial Prevention of Cardiovascular Disease through Applied Genetics
RR Williams, PN Hopkins, S Stephenson, L Wu, SC Hunt
Preventive Medicine 1999
Angiotensinogen M235T variant and salt sensitivity in young normotensive caucasians
U Schorr, K Blaschke, J Beige, A Distler, AM Sharma
Journal of Hypertension 1999
M235T angiotensinogen gene polymorphism and cardiovascular renal risk
JA Staessen, T Kuznetsova, JG Wang, D Emelianov, R Vlietinck, R Fagard
Journal of Hypertension 1999
825T allele of the G-protein β3 subunit gene (GNB3) is associated with impaired left ventricular diastolic filling in essential hypertension
J Jacobi, KF Hilgers, MP Schlaich, W Siffert, RE Schmieder
Journal of Hypertension 1999
Association of a variant of the angiotensinogen gene with pure type of hypertension in pregnancy in the Japanese: Implication of a racial difference and significance of an age factor
G Kobashi, A Hata, K Shido, EH Kato, H Yamada, S Fujimoto, R Kishi, K Kondo
American Journal of Medical Genetics 1999
Association between AGT codon 235 polymorphism and variation in serum concentrations of creatinine and urea in Canadian Oji-Cree
R Hegele, S Harris, A Hanley, B Zinman
Clinical Genetics 1999
A Sibling-Pair Analysis of Fasting Lipids and Anthropometric Measurements and Their Relationship to Hypertension
GN Thomas, RP Young, B Tomlinson, PJ Anderson, KS Woo, JE Sanderson, JA Critchley
Clinical and Experimental Hypertension 1999
Blood Pressure and the T174M and M235T Polymorphisms of the Angiotensinogen Gene
T Niu, C Chen, J Yang, B Wang, Z Wang, N Schork, Z Fang, X Xu
Annals of Epidemiology 1999
Lipoprotein-genotype associations in Trinidadian neonates
RA Hegele, MR Ban, CP Busch, S Ramsewak, DD Ramdath
Clinical Biochemistry 1999
Association between AGT T235 variant and microalbuminuria in Canadian Oji-cree with type 2 diabetes mellitus
RA Hegele, SB Harris, AJ Hanley, B Zinman
Clinical Biochemistry 1999
Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease
BR Winkelmann, AP Russ, M Nauck, B Klein, BO Böhm, V Maier, R Zotz, G Matheis, A Wolf, H Wieland, W Groß, DJ Galton, W März
American Heart Journal 1999
Angiotensinogen gene and essential hypertension in the Japanese: extensive association study and meta-analysis on six reported studies
N Kato, T Sugiyama, H Morita, H Kurihara, Y Yamori, Y Yazaki
Journal of Hypertension 1999
Angiotensinogen gene polymorphisms M235T/T174M: no excess transmission to hypertensive Chinese
T Niu, J Yang, B Wang, W Chen, Z Wang, N Laird, E Wei, Z Fang, K Lindpaintner, JJ Rogus, X Xu
Hypertension 1999
Associations of the Angiotensinogen Gene (M235T, T174M) and the Angiotensin I-Converting Enzyme Gene (I/D) with Blood Pressure in Japanese Workers
YS Kobayashi
Blood Pressure 1999
Is Angiotensinogen Gene Polymorphism Associated with Hypertension in Pregnancy?
Y Suzuki, M Tanemura, Y Suzuki, I Murakami, K Suzumori
Hypertension in Pregnancy 1999
Functional Analysis of a Mutation Occurring between the Two In-frame AUG Codons of Human Angiotensinogen
T Nakajima, T Cheng, A Rohrwasser, LJ Bloem, JH Pratt, I Inoue, JM Lalouel
The Journal of biological chemistry 1999
Effect of Chromosome 19 Transfer on Blood Pressure in the Spontaneously Hypertensive Rat
ES Lezin, L Zhang, Y Yang, JM Wang, N Wang, N Qi, JS Steadman, W Liu, V Kren, V Zidek, D Krenova, PC Churchill, MC Churchill, M Pravenec
Hypertension 1999
Maximum-Likelihood Generalized Heritability Estimate for Blood Pressure in Nigerian Families
CN Rotimi, RS Cooper, G Cao, O Ogunbiyi, M Ladipo, E Owoaje, R Ward
Hypertension 1999
1166 A/C Polymorphism of the Angiotensin II Type 1 Receptor Gene and the Response to Short-Term Infusion of Angiotensin II
KF Hilgers, MR Langenfeld, M Schlaich, R Veelken, RE Schmieder
Circulation 1999
Angiotensinogen Gene Polymorphism Near Transcription Start Site and Blood Pressure: Role of a T-to-C Transition at Intron I
T Ishigami, K Tamura, T Fujita, I Kobayashi, K Hibi, M Kihara, Y Toya, H Ochiai, S Umemura
Hypertension 1999
Epidemiology of Risk Factors for Hypertension: Implications for Prevention and Therapy
M Kornitzer, M Dramaix, GD Backer
Drugs 1999
Angiotensinogen gene and hypertension in Chinese
T Niu, X Xu, J Rogus, Y Zhou, C Chen, J Yang, Z Fang, C Schmitz, J Zhao, VS Rao, K Lindpaintner
Journal of Clinical Investigation 1998
Gene polymorphisms of the renin-angiotensin system in relation to hypertension and parental history of myocardial infarction and stroke
L Tiret, H Blanc, JB Ruidavets, D Arveiler, G Luc, X Jeunemaitre, J Tichet, C Mallet, O Poirier, PF Plouin, F Cambien
Journal of Hypertension 1998
Role of genetic variants of the renin-angiotensin system in chronic renal allograft injury
AM Sharma, J Beige, A Distler
Kidney International 1998
A Polymorphism of Angiotensinogen Gene Codon 174 and Coronary Artery Disease in Japanese Subjects
ND Cong, K Hamaguchi, T Saikawa, M Hara, T Sakata
The American Journal of the Medical Sciences 1998
A primer on the genetics of hypertension
D Cusi, G Bianchi
Kidney International 1998
SCANNING THE GENOME FOR ESSENTIAL HYPERTENSION LOCI
BJ Morris, LR Griffiths
Clinical and Experimental Pharmacology and Physiology 1998
T235 variant of the angiotensinogen gene and blood pressure in the Chilean population
CE Fardella, X Claverie, P Vignolo, J Montero, L Villarroel
Journal of Hypertension 1998
Angiotensinogen gene polymorphism is associated with insulin resistance in nondiabetic men with or without coronary heart disease
WH Sheu, WJ Lee, CY Jeng, MS Young, YA Ding, YT Chen
American Heart Journal 1998
Evaluation of the Angiotensinogen Locus in Human Essential Hypertension: A European Study
E Brand, N Chatelain, B Keavney, M Caulfield, L Citterio, J Connell, D Grobbee, S Schmidt, H Schunkert, H Schuster, AM Sharma, F Soubrier
Hypertension 1998
Lack of Association Between the α-Adducin Locus and Essential Hypertension in the Japanese Population
N Kato, T Sugiyama, T Nabika, H Morita, H Kurihara, Y Yazaki, Y Yamori
Hypertension 1998
Herz-Kreislauf-Erkrankungen
D Ganten, K Ruckpaul
1998
Associations of angiotensinogen gene mutations with hypertension and myocardial infarction in a gulf population
PM Frossard, SH Hill, YI Elshahat, EN Obineche, AM Bokhari, GG Lestringant, A John, AM Abdulle
Clinical Genetics 1998
A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
I Inoue, T Nakajima, CS Williams, J Quackenbush, R Puryear, M Powers, T Cheng, EH Ludwig, AM Sharma, A Hata, X Jeunemaitre, JM Lalouel
Journal of Clinical Investigation 1997
PATHOPHYSIOLOGY AND TREATMENT IMPLICATIONS OF HYPERTENSION IN THE AFRICAN-AMERICAN POPULATION
M Rahman, JG Douglas, JT Wright
Endocrinology & Metabolism Clinics of North America 1997
Genetic variants of the renin–angiotensin system and ambulatory blood pressure in essential hypertension
J Beige, O Zilch, H Hohenbleicher, J Ringel, R Kunz, A Distler, AM Sharma
Journal of Hypertension 1997
Renin-angiotensin system component gene polymorphisms in Japanese maintenance haemodialysis patients
N KAWADA, T MORIYAMA, K YOKOYAMA, A YAMAUCHI, A ANDO, H MIKAMI, M FUJII, Y KAJIMOTO, M HORIO, E IMAI
Nephrology 1997
Associations between candidate loci angiotensin-converting enzyme and angiotensinogen with coronary heart disease and myocardial infarction: The NHLBI family heart study
EH Ludwig, IB Borecki, RC Ellison, AR Folsom, G Heiss, M Higgins, JM Lalouel, MA Province, DC Rao
Annals of Epidemiology 1997
Molecular variant M235T of the angiotensinogen gene is associated with essential hypertension in Taiwanese
FT Chiang, KL Hsu, CD Tseng, WH Hsiao, HM Lo, TH Chern, YZ Tseng
Journal of Hypertension 1997
Haplotypes of Angiotensinogen in Essential Hypertension
X Jeunemaitre, I Inoue, C Williams, A Charru, J Tichet, M Powers, AM Sharma, AP Gimenez-Roqueplo, A Hata, P Corvol, JM Lalouel
The American Journal of Human Genetics 1997
Angiotensinogen gene variation in a population case-control study of preeclampsia/eclampsia in Australians and Chinese
G Guo, AN Wilton, Y Fu, H Qiu, SP Brennecke, DW Cooper
Electrophoresis 1997
Met 235 the polymorphism of angiotensinogen in indonesians
MM Romi, SY Patria, M Matsuo
The Japanese Journal of Human Genetics 1997
Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: The NHLBI family heart study
IB Borecki, MA Province, EH Ludwig, RC Ellison, AR Folsom, G Heiss, JM Lalouel, M Higgins, DC Rao
Annals of Epidemiology 1997
HYPERTENSION HEMODYNAMICS
FM Fouad-Tarazi
Medical Clinics of North America 1997
HYPERTENSION AND CORONARY ARTERY DISEASE
VS Srikanthan, FG Dunn
Medical Clinics of North America 1997
Angiotensinogen gene polymorphism in Japanese patients with hypertrophic cardiomyopathy
A Ishanov, H Okamoto, K Yoneya, M Watanabe, I Nakagawa, M Machida, H Onozuka, T Mikami, H Kawaguchi, A Hata, K Kondo, A Kitabatake
American Heart Journal 1997
Lack of association between variants of the angiotensinogen gene and the risk of coronary artery disease in middle-aged Japanese men
S Ichihara, M Yokota, T Fujimura, S Kato, H Hirayama, A Tsunekawa, H Inagaki, F Takatsu, N Nakashima, Y Yamada
American Heart Journal 1997
Hypertension, serum angiotensinogen, and molecular variants of the angiotensinogen gene among Nigerians
C Rotimi, R Cooper, O Ogunbiyi, L Morrison, M Ladipo, D Tewksbury, R Ward
Circulation 1997
Evidence for gene-diet interaction in the response of blood pressure to dietary fibre
RA Hegele, M Jugenberg, PW Connelly, DJ Jenkins
Nutrition Research 1997
The Angiotensinogen T235 Variant and the Use of Antihypertensive Drugs in a Population-Based Cohort
H Schunkert, HW Hense, AP Gimenez-Roqueplo, J Stieber, U Keil, GA Riegger, X Jeunemaitre
Hypertension 1997
Tissue Angiotensinogen Gene Expression Induced by Lipopolysaccharide in Hypertensive Rats
N Nyui, K Tamura, S Yamaguchi, M Nakamaru, T Ishigami, M Yabana, M Kihara, H Ochiai, N Miyazaki, S Umemura, M Ishii
Hypertension 1997
Association Between the Angiotensinogen 235T-Variant and Essential Hypertension in Whites: A Systematic Review and Methodological Appraisal
R Kunz, R Kreutz, J Beige, A Distler, AM Sharma
Hypertension 1997
Linkage of Essential Hypertension to the Angiotensinogen Locus in Mexican Americans
LD Atwood, CM Kammerer, PB Samollow, JE Hixson, RE Shade, JW MacCluer
Hypertension 1997
Angiotensinogen Gene Variation Associated With Variation in Blood Pressure in Aboriginal Canadians
RA Hegele, SB Harris, AJ Hanley, F Sun, PW Connelly, B Zinman
Hypertension 1997
Association of the Angiotensinogen Gene to Serum Angiotensinogen in Blacks and Whites
LJ Bloem, TM Foroud, WT Ambrosius, MP Hanna, DA Tewksbury, JH Pratt
Hypertension 1997
Women’s Health and Menopause: Risk Reduction Strategies
R Paoletti, PG Crosignani, P Kenemans, G Samsioe, MR Soma, AS Jackson
1997
Molecular Genetics of Human Hypertension: Role of Angiotensinogen*
P Corvol, X Jeunemaitre
Endocrine reviews 1997
Angiotensinogen: Molecular biology, biochemistry and physiology
L Morgan, FB Pipkin, N Kalsheker
The International Journal of Biochemistry & Cell Biology 1996
A study of the combination of angiotensinogen gene and ACE gene in relation to essential hypertension
S Kataoka, K Yamamoto, N Hashimoto, T Kakihara, A Tanaka, T Kawasaki, T Kikuchi, H Takahashi, M Uchiyama
Nihon Shoni Jinzobyo Gakkai Zasshi 1996
Angiotensin I converting enzyme gene polymorphism in non-insulin dependent diabetes mellitus
H Yoshida, S Kuriyama, Y Atsumi, H Tomonari, T Mitarai, A Hamaguchi, H Kubo, Y Kawaguchi, V Kon, K Matsuoka, I Ichikawa, O Sakai
Kidney International 1996
Primary renal abnormalities in hereditary hypertension
RG Woolfson, HE de Wardener
Kidney International 1996
Analysis of Met235 to Thr variant of the angiotensinogen gene in relation to the blood pressure and family history of essential hypertension in Japanese children
S Kataoka, N Hashimoto, T Kakihara, A Tanaka, T Kawasaki, T Kikuchi, H Takahashi, M Uchiyama
Pediatrics International 1996
Short Report on DNA Marker at Candidate Locus
DR Davis, AG Johnson
Clinical Genetics 1996
Cardiovascular disease and genetics of the renin-angiotensin system
SB Harrap
Heart (British Cardiac Society) 1996
Association analyses of the polymorphisms of angiotensin-converting enzyme and angiotensinogen genes with diabetic nephropathy in Japanese non-insulin-dependent diabetics
T Ohno, S Kawazu, S Tomono
Metabolism 1996
Links between hypertension and myocardial infarction
H Rakugi, H Yu, A Kamitani, Y Nakamura, M Ohishi, K Kamide, Y Nakata, S Takami, J Higaki, T Ogihara
American Heart Journal 1996
The Natural Mutation Y248C of Human Angiotensinogen Leads to Abnormal Glycosylation and Altered Immunological Recognition of the Protein
AP Gimenez-Roqueplo, I Leconte, P Cohen, D Simon, TT Guyene, J Célerier, B Pau, P Corvol, E Clauser, X Jeunemaitre
The Journal of biological chemistry 1996
A cis -Acting DNA Element Located between TATA Box and Transcription Initiation Site Is Critical in Response to Regulatory Sequences in Human Angiotensinogen Gene
K Yanai, Y Nibu, K Murakami, A Fukamizu
The Journal of biological chemistry 1996
Blood Pressure and the M235T Polymorphism of the Angiotensinogen Gene
AD Hingorani, P Sharma, H Jia, R Hopper, MJ Brown
Hypertension 1996
Variation at the Angiotensin-Converting Enzyme Gene and Angiotensinogen Gene Loci in Relation to Blood Pressure
TR Kiema, H Kauma, AO Rantala, M Lilja, A Reunanen, YA Kesäniemi, MJ Savolainen
Hypertension 1996
Angiotensinogen Polymorphism M235T, Hypertension, and Nephropathy in Insulin-Dependent Diabetes
A Doria, T Onuma, G Gearin, MB Freire, JH Warram, AS Krolewski
Hypertension 1996
Polymorphisms of Renin-Angiotensin Genes Among Nigerians, Jamaicans, and African Americans
C Rotimi, A Puras, R Cooper, N McFarlane-Anderson, T Forrester, O Ogunbiyi, LM Ward
Hypertension 1996
Angiotensinogen in Human Essential Hypertension
M Caulfield, P Lavender, J Newell-Price, S Kamdar, M Farrall, AJ Clark
Hypertension 1996
Genetic Approaches to Noncommunicable Diseases
K Berg, V Boulyjenkov, Y Christen
1996
The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children
LJ Bloem, AK Manatunga, DA Tewksbury, JH Pratt
Journal of Clinical Investigation 1995
Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans
M Caulfield, P Lavender, J Newell-Price, M Farrall, S Kamdar, H Daniel, M Lawson, PD Freitas, P Fogarty, AJ Clark
Journal of Clinical Investigation 1995
The genetics of hypertension
M Thibonnier, NJ Schork
Current Opinion in Genetics & Development 1995
A study of the angiotensinogen gene in relation to essential hypertension
S Kataoka, N Hashimoto, T Kakihara, A Tanaka, T Kawasaki, T Kikuchi, H Takahashi, M Uchiyama
Nihon Shoni Jinzobyo Gakkai Zasshi 1995
Pre-eclampsia and the angiotensinogen gene
L Morgan, P Baker, FB Pipkin, N Kalsheker
BJOG: An International Journal of Obstetrics and Gynaecology 1995
Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease
T Katsuya, G Koike, M Horiuchi, RE Pratt, VJ Dzau, TW Yee, N Sharpe, S MacMahon, R Jackson, R Norton
The Lancet 1995
Absence of association of angiotensinogen gene T235 allele with increased risk of coronary heart disease in Japanese
K Yamakawa-Kobayashi, T Arinami, H Hamaguchi
The Lancet 1995
Rapid detection and prevalence of the variants of the angiotensinogen gene in patients with essential hypertension
T Morise, Y Takeuchi, R Takeda
Journal of Internal Medicine 1995
Angiotensin converting enzyme genotypes and disease
KK Teo
BMJ (Clinical research ed.) 1995
Role of angiotensinogen in the genetics of essential hypertension
A Hata
Life Sciences 1995
Angiotensin-converting enzyme (ACE) gene polymorphism in type II diabetic patients with increased albumin excretion rate
S Panagiotopoulos, TJ Smith, GP Aldred, EJ Baker, CJ Jacklin, G Jerums
Journal of Diabetes and its Complications 1995
Angiotensinogen Gene and Blood Pressure in the Japanese Population
N Iwai, H Shimoike, N Ohmichi, M Kinoshita
Hypertension 1995
Multiple Risk Factors in Cardiovascular Disease
AM Gotto, C Lenfant, AL Catapano, R Paoletti
1995
Molecular Variant of Angiotensinogen Gene Is Associated With Coronary Atherosclerosis
T Ishigami, S Umemura, T Iwamoto, K Tamura, K Hibi, S Yamaguchi, N Nyuui, K Kimura, N Miyazaki, M Ishii
Circulation 1995
Analysis of the Role of Angiotensinogen in Spontaneous Hypertension
D Lodwick, MA Kaiser, J Harris, F Cumin, M Vincent, NJ Samani
Hypertension 1995
A Mutation of Angiotensinogen in a Patient with Preeclampsia Leads to Altered Kinetics of the Renin-Angiotensin System
I Inoue, A Rohrwasser, C Helin, X Jeunemaitre, P Crain, J Bohlender, RP Lifton, P Corvol, K Ward, JM Lalouel
The Journal of biological chemistry 1995
Genes, Hypertension, and Cardiac Hypertrophy
K Lindpaintner
New England Journal of Medicine 1994
Angiotensinogen gene in human hypertension. Lack of an association of the 235T allele among African Americans
C Rotimi, L Morrison, R Cooper, C Oyejide, E Effiong, M Ladipo, B Osotemihen, R Ward
Hypertension 1994
Functional expression of the human angiotensinogen gene in transgenic mice
G Yang, DC Merrill, MW Thompson, JE Robillard, CD Sigmund
The Journal of biological chemistry 1994
Advances in Genetics
BH Bowman, F Yang, GS Adrian
Advances in genetics 1988

← Previous 1 2 3 … 7 8 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 3 patents
26 readers on Mendeley
See more details