J Peters, K Münter, M Bader, E Hackenthal, J J Mullins, D Ganten
Title and authors | Publication | Year |
---|---|---|
Complex Pathophysiology of Acute Kidney Injury (AKI) in Aging: Epigenetic Regulation, Matrix Remodeling, and the Healing Effects of H2S
Gupta S, Mandal S, Banerjee K, Almarshood H, Pushpakumar SB, Sen U |
Biomolecules | 2024 |
Functions of the (pro)renin receptor (Atp6ap2) at molecular and system levels: pathological implications in hypertension, renal and brain development, inflammation, and fibrosis
N Hoffmann, J Peters |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2021 |
Angiotensin dependent and angiotensin independent protective effects of renin-b in H9c2 cells after anoxia
H Wanka, P Lutze, D Staar, K Bracke, J Golchert, J Peters |
Scientific Reports | 2020 |
Elevated aldosterone and blood pressure in a mouse model of familial hyperaldosteronism with ClC-2 mutation
J Schewe, E Seidel, S Forslund, L Marko, J Peters, DN Muller, C Fahlke, G Stölting, U Scholl |
Nature Communications | 2019 |
Role of angiotensin II in chronic blood pressure control of heterozygous Ren-2 transgenic rats: Peripheral vasoconstriction versus central sympathoexcitation
L Řezáčová, S Hojná, L Kopkan, H Rauchová, M Kadlecová, J Zicha, I Vaněčková |
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie | 2019 |
Stress and hypertensive disease: adrenals as a link. Experimental study on hypertensive ISIAH rat strain
YV Antonov, YV Alexandrovich, OE Redina, MA Gilinsky, AL Markel |
Clinical and Experimental Hypertension | 2016 |
The Role of Hydrogen Sulfide in Renal System
X Cao, JS Bian |
Frontiers in pharmacology | 2016 |
Renal disease pathophysiology and treatment: contributions from the rat
LJ Mullins, BR Conway, RI Menzies, L Denby, JJ Mullins |
Disease models & mechanisms | 2016 |
Drug Discovery and Evaluation: Pharmacological Assays
FJ Hock |
2016 | |
Comprehensive Physiology
SN Cheuvront, RW Kenefick |
Comprehensive Physiology | 2014 |
Genetic modifiers of hypertension in soluble guanylate cyclase α1-deficient mice
Emmanuel Buys, Michael Raher, Andrew Kirby, Shahid Mohd, David Baron, Sarah Hayton, Laurel Tainsh, Patrick Sips, Kristen Rauwerdink, Qingshang Yan, Robert Tainsh, Hannah Shakartzi, Christine Stevens, Kelly Decaluwe, Maria da Gloria Rodrigues-Machado, Rajeev Malhotra, Johan Van de Voorde, Tong Wang, Peter Brouckaert, Mark Daly, Kenneth Bloch |
Journal of Clinical Investigation | 2012 |
Combination of direct renin inhibition with angiotensin type 1 receptor blockade improves aldosterone but does not improve kidney injury in the transgenic Ren2 rat
A Whaley-Connell, J Habibi, R Nistala, MR Hayden, L Pulakat, C Sinak, B Locher, CM Ferrario, JR Sowers |
Regulatory Peptides | 2012 |
Local renin-angiotensin systems in the adrenal gland
J Peters |
Peptides | 2012 |
Parallel regulation of renin and lysosomal integral membrane protein 2 in renin-producing cells: further evidence for a lysosomal nature of renin secretory vesicles
J Schmid, M Oelbe, P Saftig, M Schwake, F Schweda |
Pflügers Archiv - European Journal of Physiology | 2012 |
Renin Release: Sites, Mechanisms, and Control
A Kurtz |
Annual Review of Physiology | 2011 |
Amiloride lowers arterial pressure in cyp1a1ren-2 transgenic rats without affecting renal vascular function
T Schlüter, R Rohsius, H Wanka, C Schmid, A Siepelmeyer, R Rettig, J Peters, O Grisk |
Journal of Hypertension | 2010 |
Cytosolic renin is targeted to mitochondria and inducesapoptosis in H9c2 rat cardiomyoblasts
H Wanka, N Keßler, J Ellmer, N Endlich, BS Peters, S Clausmeyer, J Peters |
Journal of Cellular and Molecular Medicine | 2009 |
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism
J Peters, T Schlüter, T Riegel, BS Peters, A Beineke, U Maschke, N Hosten, JJ Mullins, R Rettig |
American journal of physiology. Heart and circulatory physiology | 2009 |
Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism
J Peters, T Schlüter, T Riegel, BS Peters, A Beineke, U Maschke, N Hosten, JJ Mullins, R Rettig |
American journal of physiology. Heart and circulatory physiology | 2009 |
Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats
Y Wei, SE Clark, EM Morris, JP Thyfault, GM Uptergrove, AT Whaley-Connell, CM Ferrario, JR Sowers, JA Ibdah |
Journal of Hepatology | 2008 |
Update on tissue renin–angiotensin systems
M Bader, D Ganten |
Journal of Molecular Medicine | 2008 |
Secretory and cytosolic (pro)renin in kidney, heart, and adrenal gland
J Peters |
Journal of Molecular Medicine | 2008 |
A renin transcript lacking exon 1 encodes for a non-secretory intracellular renin that increases aldosterone production in transgenic rats
J Peters, H Wanka, B Peters, S Hoffmann |
Journal of Cellular and Molecular Medicine | 2008 |
Cardiovascular Activity
Vogel HG |
2008 | |
Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats
DJ Kelly, Y Zhang, G Moe, G Naik, RE Gilbert |
Diabetologia | 2007 |
Renal injury in streptozotocin-diabetic Ren2-transgenic rats is mainly dependent on hypertension, not on diabetes
A Hartner, N Cordasic, B Klanke, M Wittmann, R Veelken, KF Hilgers |
American journal of physiology. Renal physiology | 2007 |
Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats
A Hartner, M Porst, B Klanke, N Cordasic, R Veelken, KF Hilgers |
Nephrology Dialysis Transplantation | 2006 |
The Local Cardiac Renin Angiotensin-Aldosterone System
ED Frohlich, RN Re |
2006 | |
Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems
SO Kasper, CS Carter, CM Ferrario, D Ganten, LF Ferder, WE Sonntag, PE Gallagher, DI Diz |
Physiological genomics | 2005 |
Angiotensin Vol. I
T Unger, BA Schölkens |
2004 | |
Transgenic Models in Pharmacology
S Offermanns, L Hein |
2004 | |
Adenovirus-mediated human prostasin gene delivery is linked to increased aldosterone production and hypertension in rats
C Wang, J Chao, L Chao |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2003 |
Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor
GP Rossi, M Cavallin, D Rizzoni, S Bova, G Mazzocchi, E Agabiti-Rosei, GG Nussdorfer, AC Pessina |
Journal of Hypertension | 2002 |
Characterisation of a thymic renin–angiotensin system in the transgenic m(Ren-2)27 rat
JL Wilkinson-Berka, DJ Kelly, P Rong, DJ Campbell, SL Skinner |
Molecular and Cellular Endocrinology | 2002 |
Comparative effects of the dual ACE-NEP inhibitor MDL-100,240 and ramipril on hypertension and cardiovascular disease in endogenous angiotensin II-dependent hypertension
GP Rossi, S Bova, A Sacchetto, D Rizzoni, E Agabiti-Rosei, G Neri, GG Nussdorfer, AC Pessina |
American Journal of Hypertension | 2002 |
Functional significance of prorenin internalization in the rat heart
J Peters, R Farrenkopf, S Clausmeyer, J Zimmer, S Kantachuvesiri, MG Sharp, JJ Mullins |
Circulation research | 2002 |
Drug Discovery and Evaluation
HG Vogel, WH Vogel, BA Schölkens, J Sandow, G Müller, WF Vogel |
2002 | |
EFFECT OF SHORT LIGHT-DARK CYCLES ON YOUNG AND ADULT TGR(mREN2)27 RATS
MM Corretger, MM Canal-Corretger, K Witte, A Díez-Noguera, B Lemmer |
Chronobiology International | 2001 |
CIRCADIAN PACEMAKER FUNCTION AND ENTRAINMENT DURING MATURATION OF TRANSGENIC HYPERTENSIVE TGR(mREN2)27 AND SPRAGUE-DAWLEY RATS
MM Corretger, MM Canal-Corretger, K Witte, B Lemmer |
Chronobiology International | 2001 |
Effects of all- trans retinoic acid on renin-angiotensin system in rats with experimental nephritis
C Dechow, C Morath, J Peters, I Lehrke, R Waldherr, V Haxsen, E Ritz, J Wagner |
American journal of physiology. Renal physiology | 2001 |
Controlled Hypertension, a Transgenic Toggle Switch Reveals Differential Mechanisms Underlying Vascular Disease
S Kantachuvesiri, S Fleming, J Peters, B Peters, G Brooker, AG Lammie, I McGrath, Y Kotelevtsev, JJ Mullins |
The Journal of biological chemistry | 2001 |
CIRCADIAN RHYTHMS IN THE RENIN-ANGIOTENSIN SYSTEM AND ADRENAL STEROIDS MAY CONTRIBUTE TO THE INVERSE BLOOD PRESSURE RHYTHM IN HYPERTENSIVE TGR(mREN-2)27 RATS
B Lemmer, K Witte, A Schänzer, A Finedeisen |
Chronobiology International | 2000 |
Tissue-Specific Expression of a Rat Renin Transcript Lacking the Coding Sequence for the Prefragment and Its Stimulation by Myocardial Infarction*
S Clausmeyer, A Reinecke, R Farrenkopf, T Unger, J Peters |
Endocrinology | 2000 |
Losartan and Angiotensin II Inhibit Aldosterone Production in Anephric Rats via Different Actions on the Intraadrenal Renin-Angiotensin System 1
JÖ Peters, N ObermÜller, A Woyth, B Peters, C Maser-Gluth, B KrÄnzlin, N Gretz |
Endocrinology | 1999 |
Cardiovascular Specific Gene Expression
PA Doevendans, RS Reneman, M van Bilsen |
1999 | |
Angiotensin II AT1-Rezeptorantagonisten
P Dominiak, T Unger |
1999 | |
Techniques in Molecular Medicine
F Hildebrandt, P Igarashi |
1999 | |
Regulation of human renin gene promoter activity: A new negative regulatory region determines the responsiveness to TNFα
LS Chen, MP Cuddy, LA LaVallette |
Kidney International | 1998 |
Differential Development of Early Hypertension in Heterozygous Transgenic TGR(mREN2)27 Rats
R Kreutz, MS Fernandez-alfonso, M Paul, JÖ Peters |
Clinical and Experimental Hypertension | 1998 |
Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism
S Berger, M Bleich, W Schmid, TJ Cole, J Peters, H Watanabe, W Kriz, R Warth, R Greger, G Schütz |
Proceedings of the National Academy of Sciences | 1998 |
The TGR(mRen2)27 transgenic rat model of hypertension
S Engler, M Paul, YM Pinto |
Regulatory Peptides | 1998 |
Transgenic animal models for the functional analysis of vasoactive peptides
M Bader |
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.] | 1998 |
Mouse and rat plasma renin concentration and gene expression in (mRen2)27 transgenic rats
J Bohlender, J Ménard, O Edling, D Ganten, FC Luft |
American journal of physiology. Heart and circulatory physiology | 1998 |
Intraadrenal Interactions in the Regulation of Adrenocortical Steroidogenesis
M Ehrhart-Bornstein, JP Hinson, SR Bornstein, WA Scherbaum, GP Vinson |
Endocrine reviews | 1998 |
Brain angiotensins in the cardiovascular regulation: usefulness of transgenic animals
G Bricca, M Schinke, M Böhm, J Monti, H Hof, D Ganten, M Bader |
Fundamental & Clinical Pharmacology | 1997 |
Transgenic hypertensive rats show a reduced angiotensin II induced [Ca2+]i response in glomerular mesangial cells
M Tepel, S Heidenreich, W Zidek |
Life Sciences | 1997 |
Use of Transgenic Mice in Aging Research
A Richardson, AR Heydari, WW Morgan, JF Nelson, ZD Sharp, CA Walter |
ILAR journal / National Research Council, Institute of Laboratory Animal Resources | 1997 |
Cyclosporine and the renin-angiotensin axis
DB Lee |
Kidney International | 1997 |
Renin-1 Is Essential for Normal Renal Juxtaglomerular Cell Granulation and Macula Densa Morphology
AF Clark, MG Sharp, SD Morley, S Fleming, J Peters, JJ Mullins |
The Journal of biological chemistry | 1997 |
The renin-angiotensin system in transgenic rats
J Wagner, F Thiele, D Ganten |
Pediatric Nephrology | 1996 |
Proceedings of the Symposium ‘Angiotensin AT1 Receptors: From Molecular Physiology to Therapeutics’: TRANSGENIC RATS: TOOLS TO STUDY THE FUNCTION OF THE RENIN-ANGIOTENSIN SYSTEM
M Bader, D Ganten |
Clinical and Experimental Pharmacology and Physiology | 1996 |
Role of the Circulating Renin-Angiotensin System in the Pathogenesis of Hypertension in Transgenic Rats, TGR(mREN2)27
J Peters, KF Hilgers, C Maser-Gluth, R Kreutz |
Clinical and Experimental Hypertension | 1996 |
Behaviour of the transgenic (mREN2) 27 rat
W Wilson, P Voigt, M Bader, CA Marsden, H Fink |
Brain Research | 1996 |
Presence of renin within intramitochondrial dense bodies of the rat adrenal cortex
J Peters, B Kranzlin, S Schaeffer, J Zimmer, S Resch, S Bachmann, N Gretz, E Hackenthal |
American journal of physiology. Endocrinology and metabolism | 1996 |
Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade
M Bhm, A Lippoldt, W Wienen, D Ganten, M Bader |
Molecular and Cellular Biochemistry | 1996 |
Targeted Inactivation of the Ren-2 Gene in Mice
MG Sharp, D Fettes, G Brooker, AF Clark, J Peters, S Fleming, JJ Mullins |
Hypertension | 1996 |
Salt-Sensitive Hypertension in ( m REN-2)27 Transgenic Rats
MF Callahan, P Li, CM Ferrario, D Ganten, M Morris |
Hypertension | 1996 |
Biochemical Regulation of Myocardium
R Vetter, EG Krause |
1996 | |
Study of the rat adrenal renin-angiotensin system at a cellular level
CY Chiou, GH Williams, I Kifor |
Journal of Clinical Investigation | 1995 |
Molecular basis of human hypertension: The role of angiotensin
J Peters |
Baillière's Clinical Endocrinology and Metabolism | 1995 |
A genetic model of malignant phase hypertension in rats
CE Whitworth, S Fleming, Y Kotelevtsev, L Manson, GA Brooker, AD Cumming, JJ Mullins |
Kidney International | 1995 |
The genetics of hypertension
M Thibonnier, NJ Schork |
Current Opinion in Genetics & Development | 1995 |
Morphology and function of the adrenal zona glomerulosa of transgenic rats TGR [mREN2] 27: Effects of prolonged sodium restriction
P Rebuffat, S Rocco, PG Andreis, G Neri, KW Nowak, J Peters, G Opocher, G Mazzocchi, F Mantero, GG Nussdorfer |
The Journal of Steroid Biochemistry and Molecular Biology | 1995 |
Transgenic animals in the study of blood pressure regulation and hypertension
MW Thompson, DC Merrill, G Yang, JE Robillard, CD Sigmund |
American journal of physiology. Endocrinology and metabolism | 1995 |
Differential Gene Expression of Renin and Angiotensinogen in the TGR(mREN-2)27 Transgenic Rat
MA Lee, M Böhm, S Kim, S Bachmann, J Bachmann, M Bader, D Ganten |
Hypertension | 1995 |
Angiotensin and Bradykinin Peptides in the TGR(mRen-2)27 Rat
DJ Campbell, P Rong, A Kladis, B Rees, D Ganten, SL Skinner |
Hypertension | 1995 |
Effect of Captopril and Angiotensin II Receptor Blockade on Pressure Natriuresis in Transgenic TGR(mRen-2)27 Rats
V Gross, A Lippoldt, W Schneider, FC Luft |
Hypertension | 1995 |
Regulation of Aldosterone Biosynthesis by Adrenal Renin Is Mediated Through AT 1 Receptors in Renin Transgenic Rats
M Volpe, S Rubattu, B Gigante, D Ganten, A Porcellini, R Russo, M Romano, I Enea, MA Lee, B Trimarco |
Circulation research | 1995 |
Tissue Renin-Angiotensin Systems
AK Mukhopadhyay, MK Raizada |
1995 | |
Enhanced adrenal renin and aldosterone biosynthesis during sodium restriction in TGR (mREN2)27
S Rubattu, I Enea, D Ganten, D Salvatore, G Condorelli, G Condorelli, R Russo, M Romano, B Gigante, B Trimarco, et |
American journal of physiology. Endocrinology and metabolism | 1994 |
Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study
S Rocco, P Rebuffat, M Cimolato, G Opocher, J Peters, G Mazzocchi, D Ganten, F Mantero, GG Nussdorfer |
Cell and Tissue Research | 1994 |
Beta-adrenergic neuroeffector mechanisms in cardiac hypertrophy of renin transgenic rats
M Böhm, M Moll, B Schmid, M Paul, D Ganten, M Castellano, E Erdmann |
Hypertension | 1994 |
Transgenes, hypotheses, and hypertension
JJ Mullins, LJ Mullins |
Hypertension | 1994 |
Transgenic models of hypertension: useful tools or unusual toys?
TW Kurtz |
Journal of Clinical Investigation | 1993 |