Successful treatment of muscular disorders awaits an adapted gene delivery protocol. The clinically applicable technique used for hematopoietic cells which is centered around implantation of retrovirally modified cells may not prove sufficient for a reversal of phenotype when muscle diseases are concerned. We report here efficient, long-term in vivo gene transfer throughout mouse skeletal and cardiac muscles after intravenous administration of a recombinant adenovirus. This simple, direct procedure raises the possibility that muscular degenerative diseases might one day be treatable by gene therapy.
L D Stratford-Perricaudet, I Makeh, M Perricaudet, P Briand
Title and authors | Publication | Year |
---|---|---|
The road toward AAV-mediated gene therapy of Duchenne muscular dystrophy
Bengtsson NE, Tasfaout H, Chamberlain JS |
Molecular Therapy | 2025 |
Cardiac-Targeting Peptide: From Discovery to Applications.
Sahagun D, Zahid M |
Biomolecules | 2023 |
Cancer immunotherapies: A hope for the uncurable?
Hamdan F, Cerullo V |
2023 | |
mRNA therapy for myocardial infarction: A review of targets and delivery vehicles.
Wang X, Wu DH, Senyo SE |
Frontiers in Bioengineering and Biotechnology | 2022 |
MicroRNA-Related Strategies to Improve Cardiac Function in Heart Failure
H Zhou, W Tang, J Yang, J Peng, J Guo, C Fan |
Frontiers in Cardiovascular Medicine | 2021 |
Targeted delivery of therapeutic agents to the heart
S Sahoo, T Kariya, K Ishikawa |
Nature Reviews Cardiology | 2021 |
DNA-PK phosphorylation at Ser2056 during adenovirus E4 mutant infection is promoted by viral DNA replication and independent of the MRN complex
C Chen, E Bridge |
Virology | 2021 |
Systemic delivery of adeno-associated viral vectors
D Duan |
Current Opinion in Virology | 2016 |
CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses
M Yuan, E Webb, N Lemoine, Y Wang |
Viruses | 2016 |
Spacial and Temporal Patterns of Gene Expression After Cardiac MEK1 Gene Transfer Improve Post-Infarction Remodeling Without Inducing Global Hypertrophy: MEK1 G ENE T RANSFER I MPROVES P OST -MI R EMODELING
Y Fan, YL Yang, CC Yeh, MJ Mann |
Journal of Cellular Biochemistry | 2016 |
Surmounting limited gene delivery into primary immune cell populations: Efficient cell type-specific adenoviral transduction by CAR: HIGHLIGHTS
BE Clausen, A Brand, K Karram |
European Journal of Immunology | 2015 |
Cardiac Electrophysiology: From Cell to Bedside
F Yang, MP Turakhia, VF Froelicher |
Cardiac Electrophysiology: From Cell to Bedside | 2014 |
Gene Therapy Delivery Systems for Enhancing Viral and Nonviral Vectors for Cardiac Diseases: Current Concepts and Future Applications
MG Katz, AS Fargnoli, RD Williams, CR Bridges |
Human Gene Therapy | 2013 |
Therapeutic potential of genes in cardiac repair
SN Pal, T Kofidis |
Expert Review of Cardiovascular Therapy | 2013 |
Vaccines
RW Sutter, OM Kew, SL Cochi, RB Aylward |
Human vaccines | 2013 |
G Protein-Coupled Receptor Genetics
CW Stevens |
2013 | |
Differential activation of cellular DNA damage responses by replication-defective and replication-competent adenovirus mutants
A Prakash, S Jayaram, E Bridge |
Journal of virology | 2012 |
Duchenne muscular dystrophy gene therapy: Lost in translation?
D Duan |
Research and Reports in Biology | 2011 |
The evolution of heart gene delivery vectors
NB Wasala, JH Shin, D Duan |
The Journal of Gene Medicine | 2011 |
Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver
W Tao, JP Davide, M Cai, GJ Zhang, VJ South, A Matter, B Ng, Y Zhang, L Sepp-Lorenzino |
Molecular Therapy | 2010 |
Schwann cell delivery of neurotrophic factors for peripheral nerve regeneration
S Madduri, B Gander |
Journal of the Peripheral Nervous System | 2010 |
Cummings Otolaryngology - Head and Neck Surgery
BW O’Malley, D Li, WM Abuzeid, H Staecker |
Cummings Otolaryngology - Head and Neck Surgery | 2010 |
Ultrasonographic Development of the Fetal Sheep Stomach and Evaluation of Early Gestation Ultrasound-guided In Utero Intragastric Injection
AL David, KN Abi-Nader, B Weisz, SW Shaw, M Themis, T Cook, C Coutelle, CH Rodeck, DM Peebles |
Taiwanese Journal of Obstetrics and Gynecology | 2010 |
A simple technique to establish a long-term adenovirus mediated gene transfer to the heart of newborn mice
M Jerebtsova, X Ye, PE Ray |
Cardiovascular & hematological disorders drug targets | 2009 |
Intra-amniotic Delivery of CFTR-expressing Adenovirus Does Not Reverse Cystic Fibrosis Phenotype in Inbred CFTR-knockout Mice
SM Buckley, SN Waddington, S Jezzard, A Bergau, M Themis, LJ MacVinish, AW Cuthbert, WH Colledge, C Coutelle |
Molecular Therapy | 2008 |
Wnt Signaling Inhibits Forkhead Box O3a-induced Transcription and Apoptosis through Up-regulation of Serum- and Glucocorticoid-inducible Kinase 1
M Dehner, M Hadjihannas, J Weiske, O Huber, J Behrens |
The Journal of biological chemistry | 2008 |
Dendrimers in Oncology: An Expanding Horizon
RK Tekade, PV Kumar, NK Jain |
Chemical Reviews | 2008 |
Inducible cAMP early repressor (ICER)-evoked delayed neuronal death in the organotypic hippocampal culture
B Mioduszewska, J Jaworski, AW Szklarczyk, A Klejman, L Kaczmarek |
Journal of Neuroscience Research | 2007 |
Post-Genomic Cardiology
J Marín-García, MJ Goldenthal, GW Moe |
Post-Genomic Cardiology | 2007 |
Different modulation of cellular transcription by adenovirus 5, ΔE1/E3 adenovirus and helper-dependent vectors
Y Martina, D Avitabile, S Piersanti, G Cherubini, I Saggio |
Virus Research | 2007 |
Phosphorylation of APP695 at Thr668 decreases γ-cleavage and extracellular Aβ
C Feyt, N Pierrot, B Tasiaux, JV Hees, P Kienlen-Campard, PJ Courtoy, JN Octave |
Biochemical and Biophysical Research Communications | 2007 |
β-Dystroglycan as a Target for MMP-9, in Response to Enhanced Neuronal Activity
P Michaluk, L Kolodziej, B Mioduszewska, GM Wilczynski, J Dzwonek, J Jaworski, DC Gorecki, OP Ottersen, L Kaczmarek |
The Journal of biological chemistry | 2007 |
1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase
M Barkats, P Horellou, P Colin, S Millecamps, N Faucon-Biguet, J Mallet |
Journal of Neuroscience Research | 2006 |
Efficacy of Therapeutic Angiogenesis by Intramyocardial Injection of pCK-VEGF165 in Pigs
JS Choi, KB Kim, W Han, DS Kim, JS Park, JJ Lee, DS Lee |
The Annals of Thoracic Surgery | 2006 |
Lactacystin decreases amyloid-β peptide production by inhibiting β-secretase activity
P Kienlen-Campard, C Feyt, S Huysseune, P Diesbach, F N'Kuli, PJ Courtoy, JN Octave |
Journal of Neuroscience Research | 2006 |
Clinically Applicable Procedure for Gene Delivery to Fetal Gut by Ultrasound-Guided Gastric Injection: Toward Prenatal Prevention of Early-Onset Intestinal Diseases
AL David, DM Peebles, L Gregory, SN Waddington, M Themis, B Weisz, A Ruthe, L Lawrence, T Cook, CH Rodeck, C Coutelle |
Human Gene Therapy | 2006 |
Isolation of targeted AAV2 vectors from novel virus display libraries
DA Waterkamp, OJ Müller, Y Ying, M Trepel, JA Kleinschmidt |
The Journal of Gene Medicine | 2006 |
Duchenne Muscular Dystrophy: Advances in Therapeutics
JS Chamberlain, TA Rando |
2006 | |
Optimization of Gene Transfer into Neonatal Rat Cardiomyocytes and Unmasking of Cytomegalovirus Promoter Silencing
S Bauer, SK Maier, L Neyses, AH Maass |
DNA and Cell Biology | 2005 |
Comparative Efficacy of Intratracheal Adeno-Associated Virus Administration to Newborn Rats
E Fleurence, C Riviere, T Lacaze-Masmonteil, ML Franco-Motoya, P Waszak, J Bourbon, O Danos, AM Douar, C Delacourt |
Human Gene Therapy | 2005 |
Amino-Terminal Fragment of Urokinase Inhibits Tumor Cell Invasion In Vitro and In Vivo: Respective Contribution of the Urokinase Plasminogen Activator Receptor-Dependent or -Independent Pathway
H Li, C Soria, F Griscelli, P Opolon, J Soria, P Yeh, C Legrand, JP Vannier, D Belin, M Perricaudet, H Lu |
Human Gene Therapy | 2005 |
Enhanced brain angiogenesis in chronic cerebral hypoperfusion after administration of plasmid human vascular endothelial growth factor in combination with indirect vasoreconstructive surgery
N Kusaka, K Sugiu, K Tokunaga, A Katsumata, A Nishida, K Namba, H Hamada, H Nakashima, I Date |
Journal of Neurosurgery | 2005 |
Amino-Terminal Fragment of Urokinase Inhibits Tumor Cell InvasionIn VitroandIn Vivo: Respective Contribution of the Urokinase Plasminogen Activator Receptor-Dependent or -Independent Pathway
H Li, C Soria, F Griscelli, P Opolon, J Soria, P Yeh, C Legrand, JP Vannier, D Belin, M Perricaudet, H Lu |
Human Gene Therapy | 2005 |
A conformational change in the adeno-associated virus type 2 capsid leads to the exposure of hidden VP1 N termini
S Kronenberg, B Böttcher, CW von der Lieth, S Bleker, JA Kleinschmidt |
Journal of virology | 2005 |
Studies on in vivo gene transfer in pituitary tumors using herpes-derived and adenoviral vectors
NG Carri, YE Sosa, OA Brown, C Albariño, V Romanowski, RG Goya |
Brain Research Bulletin | 2005 |
International Review of Neurobiology
ZT Bloomgarden |
International review of neurobiology | 2005 |
Laboratory Techniques in Biochemistry and Molecular Biology
S Chen, KM Madsen, CC Tisher, A Agarwal |
Laboratory Techniques in Biochemistry and Molecular Biology | 2005 |
Full kringles of plasminogen (aa 1-566) mediate complete regression of human MDA-MB-231 breast tumor xenografted in nude mice
A Galaup, C Magnon, V Rouffiac, P Opolon, D Opolon, N Lassau, T Tursz, M Perricaudet, F Griscelli |
Gene Therapy | 2005 |
Fatty acids induce L-CPT I gene expression through a PPARalpha-independent mechanism in rat hepatoma cells
JF Louet, F Chatelain, JF Decaux, EA Park, C Kohl, T Pineau, J Girard, JP Pegorier |
The Journal of nutrition | 2005 |
Reversal of the phenotype by K-rasval12 silencing mediated by adenovirus-delivered siRNA in human pancreatic cancer cell line Panc-1
Li-Mo Chen, Huang-Ying Le, Ren-Yi Qin, Manoj Kumar, Zhi-Yong Du, Rui-Juan Xia, Jing Deng |
World journal of gastroenterology : WJG | 2005 |
Reversal of the phenotype by K-ras val12 silencing mediated by adenovirus-delivered siRNA in human pancreatic cancer cell line Panc-1
LM Chen |
World journal of gastroenterology : WJG | 2005 |
Cancer Gene Therapy
M Yamamoto, DT Curiel |
Technology in cancer research & treatment | 2005 |
Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockade
M Hayase, F Monte, Y Kawase, BD MacNeill, J McGregor, R Yoneyama, K Hoshino, T Tsuji, AM de Grand, JK Gwathmey, JV Frangioni, RJ Hajjar |
American journal of physiology. Heart and circulatory physiology | 2005 |
Factors Influencing Adenovirus-Mediated Airway Transduction in Fetal Mice
SM Buckley, SN Waddington, S Jezzard, L Lawrence, H Schneider, MV Holder, M Themis, C Coutelle |
Molecular Therapy | 2005 |
Lithium Chloride Increases the Production of Amyloid-β Peptide Independently from Its Inhibition of Glycogen Synthase Kinase 3
C Feyt, P Kienlen-Campard, K Leroy, F N'Kuli, PJ Courtoy, JP Brion, JN Octave |
The Journal of biological chemistry | 2005 |
Reflecting on 80 years of excellence
U Savla |
Journal of Clinical Investigation | 2004 |
Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinases-1 in the liver: efficient protection against T-cell lymphoma and colon carcinoma metastasis
S Elezkurtaj, C Kopitz, AH Baker, A Perez-Cant�, MJ Arlt, R Khokha, B Gansbacher, M Anton, K Brand, A Kr�ger |
The Journal of Gene Medicine | 2004 |
Intraneuronal amyloid-β1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
N Pierrot, P Ghisdal, AS Caumont, JN Octave |
Journal of Neurochemistry | 2004 |
Delivery of GDNF by an E1,E3/E4 deleted adenoviral vector and driven by a GFAP promoter prevents dopaminergic neuron degeneration in a rat model of Parkinson's disease
NA Thi, P Saillour, L Ferrero, JF Dedieu, J Mallet, T Paunio |
Gene Therapy | 2004 |
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells
T Honda, S Coppola, L Ghibelli, SH Cho, S Kagawa, KB Spurgers, SM Brisbay, JA Roth, RE Meyn, B Fang, TJ McDonnell |
Cancer Gene Therapy | 2004 |
Mammalian cell transduction and internalization properties of λ phages displaying the full-length adenoviral penton base or its central domain
S Piersanti, G Cherubini, Y Martina, B Salone, D Avitabile, F Grosso, E Cundari, GD Zenzo, I Saggio |
Journal of Molecular Medicine | 2004 |
Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero
D Peebles, LG Gregory, A David, M Themis, SN Waddington, HJ Knapton, M Miah, T Cook, L Lawrence, M Nivsarkar, C Rodeck, C Coutelle |
Gene Therapy | 2003 |
A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia
A Ehrhardt, H Xu, AM Dillow, DA Bellinger, TC Nichols, MA Kay |
Blood | 2003 |
Viral IL-10 Gene Transfer Inhibits the Expression of Multiple Chemokine and Chemokine Receptor Genes Induced by Inflammatory or Adaptive Immune Stimuli
D Chen, Y Ding, N Zhang, B Schroppel, S Fu, W Zang, H Zhang, WW Hancock, JS Bromberg |
American Journal of Transplantation | 2003 |
Adenovirus-mediated gene transfer to the transplanted piglet heart after intracoronary injection
F Griscelli, E Belli, P Opolon, K Musset, E Connault, M Perricaudet, A Serraf, GM Mazmanian, T Ragot |
The Journal of Gene Medicine | 2003 |
Differential Chemokine and Chemokine Receptor Gene Induction by Ischemia, Alloantigen, and Gene Transfer in Cardiac Grafts
D Chen, Y Ding, B Schroppel, N Zhang, S Fu, D Chen, H Zhang, JS Bromberg |
American Journal of Transplantation | 2003 |
Hybrid Yeast-Bacteria Cloning System Used to Capture and Modify Adenoviral and Nonviral Genomes
CA Hokanson, E Dora, BA Donahue, M Rivkin, M Finer, MJ Mendez |
Human Gene Therapy | 2003 |
Ultrasound-Guided Percutaneous Delivery of Adenoviral Vectors Encoding the -Galactosidase and Human Factor IX Genes to Early Gestation Fetal Sheep In Utero
A David, T Cook, S Waddington, D Peebles, M Nivsarkar, H Knapton, M Miah, T Dahse, D Noakes, H Schneider, C Rodeck, C Coutelle, M Themis |
Human Gene Therapy | 2003 |
Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders
PR Lowenstein, D Suwelack, J Hu, X Yuan, M Jimenez-Dalmaroni, S Goverdhana, MG Castro |
International review of neurobiology | 2003 |
Development and validation of a real-time PCR assay for the detection and quantitation of p53 recombinant adenovirus in clinical samples from patients treated with Ad5CMV-p53 (INGN 201)
P Saulnier, M Vidaud, E Gautier, N Motté, D Bellet, B Escudier, D Wilson, A Yver |
Journal of Virological Methods | 2003 |
Gene therapy: theoretical and bioethical concepts
KR Smith |
Archives of Medical Research | 2003 |
Optimized, highly efficient transfer of foreign genes into newborn mouse hearts in vivo
H Ebelt, T Braun |
Biochemical and Biophysical Research Communications | 2003 |
In vivo high-efficiency transcoronary gene delivery and Cre–LoxP gene switching in the adult mouse heart
M Iwatate, Y Gu, T Dieterle, Y Iwanaga, KL Peterson, M Hoshijima, KR Chien, J Ross |
Gene Therapy | 2003 |
Adenovirus transduction induces expression of multiple chemokines and chemokine receptors in murine beta cells and pancreatic islets
Nan Zhang, Bernd Schröppel, Dongmei Chen, Shuang Fu, Kelly L Hudkins, Haojiang Zhang, Barbara M Murphy, Randall S Sung, Jonathan S Bromberg |
American Journal of Transplantation | 2003 |
Ophthalmic Drug Delivery Systems, Second Edition
J Tombran-Tink |
Ophthalmic Drug Delivery Systems, Second Edition | 2003 |
Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells
K Gelse, K von der Mark, T Aigner, J Park, H Schneider |
Arthritis & Rheumatism | 2003 |
Recombinant adenovirus shedding after intratumoral gene transfer in lung cancer patients
F Griscelli, P Opolon, P Saulnier, F Mami-Chouaib, E Gautier, H Echchakir, E Angevin, TL Chevalier, V Bataille, P Squiban, T Tursz, B Escudier |
Gene Therapy | 2003 |
In vitro and in vivo comparative study of chimeric liver-specific promoters
MG Kramer, M Barajas, N Razquin, P Berraondo, M Rodrigo, C Wu, C Qian, P Fortes, J Prieto |
Molecular Therapy | 2003 |
IFN-γ sensitization of prostate cancer cells to fas-mediated death: a gene therapy approach
WA Selleck, SE Canfield, WA Hassen, M Meseck, AI Kuzmin, RC Eisensmith, SH Chen, SJ Hall |
Molecular Therapy | 2003 |
Molecular Basis for Microcirculatory Disorders
GW Schmid-Schönbein, DN Granger |
2003 | |
Inducible cAMP early repressor, an endogenous antagonist of cAMP responsive element-binding protein, evokes neuronal apoptosis in vitro
Jacek Jaworski, Barbara Mioduszewska, Amelia Sánchez-Capelo, Izabela Figiel, Agata Habas, Agata Gozdz, Tomasz Proszynski, Michal Hetman, Jacques Mallet, Leszek Kaczmarek |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2003 |
Inducible cAMP Early Repressor, an Endogenous Antagonist of cAMP Responsive Element-Binding Protein, Evokes Neuronal Apoptosis In Vitro
Jaworski J, Mioduszewska B, Sánchez-Capelo A, Figiel I, Habas A, Gozdz A, Proszynski T, Hetman M, Mallet J, Kaczmarek L |
Journal of Neuroscience | 2003 |
Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse
M Kalamarides, M Niwa-Kawakita, H Leblois, V Abramowski, M Perricaudet, A Janin, G Thomas, DH Gutmann, M Giovannini |
Genes & development | 2002 |
Failure of the interaction between presenilin 1 and the substrate of γ-secretase to produce Aβ in insect cells
D Pitsi, P Kienlen-Campard, JN Octave |
Journal of Neurochemistry | 2002 |
A MAGE-3 peptide presented by HLA-B44 is also recognized by cytolytic T lymphocytes on HLA-B18
J Bilsborough, C Panichelli, MT Duffour, G Warnier, C Lurquin, ES Schultz, K Thielemans, J Corthals, T Boon, P der Bruggen |
Tissue Antigens | 2002 |
Neuronal transfer of the human Cu/Zn superoxide dismutase gene increases the resistance of dopaminergic neurons to 6-hydroxydopamine
M Barkats, S Millecamps, A Bilang-Bleuel, J Mallet |
Journal of Neurochemistry | 2002 |
Adenoviral Retrograde Gene Transfer in Motoneurons Is Greatly Enhanced by Prior Intramuscular Inoculation with Botulinum Toxin
S Millecamps, J Mallet, M Barkats |
Human Gene Therapy | 2002 |
Transposition of the Thyroid Iodide Uptake and Organification System in Nonthyroid Tumor Cells by Adenoviral Vector-Mediated Gene Transfers
A Boland, C Magnon, S Filetti, JM Bidart, M Schlumberger, P Yeh, M Perricaudet |
Thyroid | 2002 |
Adenovirus and Adeno-Associated Virus Vectors
CM Lai, YK Lai, PE Rakoczy |
DNA and Cell Biology | 2002 |
Effect of Intratracheal Adenoviral Vector Administration on Lung Development in Newborn Rats
P Waszak, ML Franco-Montoya, MP Jacob, I Deprez, M Levame, C Lafuma, A Harf, C Delacourt |
Human Gene Therapy | 2002 |
Methods in Cell Biology
JW Smith |
Methods in cell biology | 2002 |
Adenoviral Vectors for Gene Therapy
D Kirn |
Adenoviral Vectors for Gene Therapy | 2002 |
Binding of Adenovirus to Its Receptors in Mouse Astrocytes Induces c-fos Proto-Oncogene and Apoptosis
N Rubio, B Martin-Clemente |
Virology | 2002 |
Gene Therapy of Cancer
IV Lebedeva, CA Stein |
Gene Therapy of Cancer | 2002 |
Gene Therapy in Lung Disease
K Amin |
Gene Therapy in Lung Disease | 2002 |
Differential sensitivity of endothelial cells of various species to apoptosis induced by gene transfer of Fas ligand: role of FLIP levels
D Bouchet, L Tesson, S Ménoret, B Charreau, P Mathieu, H Yagita, G Duisit, I Anegon |
Molecular Medicine | 2002 |
Gene transfer in higher animals: theoretical considerations and key concepts
KR Smith |
Journal of Biotechnology | 2002 |
Expression of a green fluorescence protein-carrier protein into mouse spermatozoa
T Mogas, JM Fernández-Novell, MJ Palomo, PJ Otaegui, RR Gomis, J Ballester, D Izquierdo, JJ Guinovart, JC Ferrer, T Rigau, JE Rodrı́guez-Gil |
Biochemical and Biophysical Research Communications | 2002 |
Introduction to cancer gene therapy
JC Cusack, KK Tanabe |
Surgical oncology clinics of North America | 2002 |
Correlation between β-amyloid peptide production and human APP-induced neuronal death
P Kienlen-Campard, JN Octave |
Peptides | 2002 |
Increasing Local Levels of IGF-I mRNA Expression Using Adenoviral Vectors Does Not Alter Oligodendrocyte Remyelination in the CNS of Aged Rats
MT O'Leary, GL Hinks, HM Charlton, RJ Franklin |
Molecular and Cellular Neuroscience | 2002 |
Targeted gene therapy for the treatment of cardiac dysfunction
AT Askari, MS Penn |
Seminars in Thoracic and Cardiovascular Surgery | 2002 |
The Production of a New MAGE-3 Peptide Presented to Cytolytic T Lymphocytes by HLA-B40 Requires the Immunoproteasome
ES Schultz, J Chapiro, C Lurquin, S Claverol, O Burlet-Schiltz, G Warnier, V Russo, S Morel, F Lévy, T Boon, BJ van Eynde, P der Bruggen |
Journal of Experimental Medicine | 2002 |
Intracellular Amyloid-β1–42, but Not Extracellular Soluble Amyloid-β Peptides, Induces Neuronal Apoptosis
P Kienlen-Campard, S Miolet, B Tasiaux, JN Octave |
The Journal of biological chemistry | 2002 |
Gene therapy for prostate cancer: toxicological profile of four HSV-tk transducing adenoviral vectors regulated by different promoters
S Ebara, S Shimura, Y Nasu, H Kaku, H Kumon, G Yang, J Wang, TL Timme, E Aguilar-Cordova, TC Thompson |
Prostate Cancer and Prostatic Diseases | 2002 |
Transrectal gene therapy of the prostate in the canine model
KJ Weld, BE Mayher, JA Allay, JL Cockroft, CP Reed, MM Randolph, Y Lu, MS Steiner, JR Gingrich |
Cancer Gene Therapy | 2002 |
Adenoviral and adeno-associated viral vector mediated gene transfer in the guinea pig cochlea:
ML Duan, T Bordet, M Mezzina, A Kahn, M Ulfendahl |
NeuroReport | 2002 |
Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer
K Gelse, QJ Jiang, T Aigner, T Ritter, K Wagner, E P�schl, KV der Mark, H Schneider |
Arthritis & Rheumatism | 2001 |
AdTIMP-2 Inhibits Tumor Growth, Angiogenesis, and Metastasis, and Prolongs Survival in Mice
H Li, F Lindenmeyer, C Grenet, P Opolon, S Menashi, C Soria, P Yeh, M Perricaudet, H Lu |
Human Gene Therapy | 2001 |
Protection Against Fas-Mediated and Tumor Necrosis Factor Receptor 1-Mediated Liver Injury by Blockade of FADD Without Loss of Nuclear Factor-κB Activation
K Seino, Y Setoguchi, T Ogino, N Kayagaki, H Akiba, H Nakano, H Taniguchi, Y Takada, K Yuzawa, T Todoroki, Y Fukuchi, H Yagita, K Okumura, K Fukao |
Annals of Surgery | 2001 |
A single element in the phosphoenolpyruvate carboxykinase gene mediates thiazolidinedione action specifically in adipocytes
M Glorian, E Duplus, EG Beale, DK Scott, DK Granner, C Forest |
Biochimie | 2001 |
Combination of Electroporation and DNA/Dendrimer Complexes Enhances Gene Transfer into Murine Cardiac Transplants
Y Wang, Y Bai, C Price, P Boros, L Qin, AU Bielinska, JF Kukowska-Latallo, JR Baker, JS Bromberg |
American Journal of Transplantation | 2001 |
Increasing endothelial cell permeability improves the efficiency of myocyte adenoviral vector infection
N Nevo, N Chossat, W Gosgnach, D Logeart, JJ Mercadier, JB Michel |
The Journal of Gene Medicine | 2001 |
Optimised helper virus-free production of high-quality adeno-associated virus vectors
L Drittanti, C Jenny, K Poulard, A Samba, P Manceau, N Soria, N Vincent, O Danos, M Vega |
The Journal of Gene Medicine | 2001 |
Inhibition of Angiogenesis by Adenovirus-Mediated sFlt-1 Expression in a Rat Model of Corneal Neovascularization
CM Lai, M Brankov, T Zaknich, YK Lai, WY Shen, IJ Constable, I Kovesdi, PE Rakoczy |
Human Gene Therapy | 2001 |
Protection against Fas-mediated and tumor necrosis factor receptor 1-mediated liver injury by blockade of FADD without loss of nuclear factor-kappaB activation
K Seino, Y Setoguchi, T Ogino, N Kayagaki, H Akiba, H Nakano, H Taniguchi, Y Takada, K Yuzawa, T Todoroki, Y Fukuchi, H Yagita, K Okumura, K Fukao |
Annals of Surgery | 2001 |
Adenovirus-mediated expression of interleukin-1 receptor antagonist in swine cells in vitro and in vivo
DF Morrison, MP Murtaugh |
Veterinary Immunology and Immunopathology | 2001 |
Heart Physiology and Pathophysiology
NS Dhalla, RM Temsah, T Netticadan, MS Sandhu |
Heart Physiology and Pathophysiology | 2001 |
Synaptic sprouting increases the uptake capacities of motoneurons in amyotrophic lateral sclerosis mice
S Millecamps, D Nicolle, I Ceballos-Picot, J Mallet, M Barkats |
Proceedings of the National Academy of Sciences | 2001 |
Surgical Research
J Rozga, AA Demetriou |
Surgical Research | 2001 |
Binding Properties, Cell Delivery, and Gene Transfer of Adenoviral Penton Base Displaying Bacteriophage
MD Giovine, B Salone, Y Martina, V Amati, G Zambruno, E Cundari, CM Failla, I Saggio |
Virology | 2001 |
Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: a rodent model of IL-4-induced hepatitis
C Guillot, H Coathalem, J Chetritt, A David, P Lowenstein, E Gilbert, L Tesson, N Rooijen, MC Cuturi, JP Soulillou, I Anegon |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
Adult cardiac myocytes survive and remain excitable during long-term culture on synthetic supports
TA Folliguet, C Rücker-Martin, C Pavoine, E Deroubaix, M Henaff, JJ Mercadier, SN Hatem |
The Journal of Thoracic and Cardiovascular Surgery | 2001 |
Tumor-specific gene expression in hepatic metastases by a replication-activated adenovirus vector
DS Steinwaerder, CA Carlson, DL Otto, ZY Li, S Ni, A Lieber |
Nature Medicine | 2001 |
PROLONGATION OF ALLOGRAFT SURVIVAL WITH VIRAL IL-10 TRANSFECTION IN A HIGHLY HISTOINCOMPATIBLE MODEL OF RAT HEART ALLOGRAFT REJECTION1:
X Zuo, C Wang, D Carpenter, Y Okada, E Nicolaidou, M Toyoda, A Trento, SC Jordan |
Transplantation | 2001 |
Surgery
JA Norton, RR Bollinger, AE Chang, SF Lowry, SJ Mulvihill, HI Pass, RW Thompson |
Surgery | 2001 |
Effects of adenoviral wild-type p53 gene transfer in p53 -mutated lymphoma cells
P Buttgereit, F Schakowski, A Märten, K Brand, S Renoth, C Ziske, B Schöttker, O Ebert, R Schroers, IG Schmidt-Wolf |
Cancer Gene Therapy | 2001 |
Animal Cell Technology: From Target to Market
E Lindner-Olsson, N Chatzissavidou, E Lüllau |
2001 | |
Chromosomal Integration Pattern of a Helper-Dependent Minimal Adenovirus Vector with a Selectable Marker Inserted into a 27.4-Kilobase Genomic Stuffer
M Hillgenberg, H Tönnies, M Strauss |
Journal of virology | 2001 |
Adenovirus vector-directed expression of the neurotrophin-3 receptor (TrkC) in mouse astrocytes
JA Rubio |
Journal of Neurovirology | 2001 |
Partial Correction of the Urinary Concentrating Defect in Aquaporin-1 Null Mice by Adenovirus-Mediated Gene Delivery
Baoxue Yang, Tonghui, J.-Y. Dong, A.S. Verkman |
Human Gene Therapy | 2000 |
Gene therapy for vein grafts
MJ Mann |
Current Cardiology Reports | 2000 |
Recent developments in gene therapy for cardiac disease
S Wattanapitayakul |
Biomedecine & Pharmacotherapy | 2000 |
Cystic Fibrosis Transmembrane Conductance Regulator Does Not Affect Neutrophil Migration across Cystic Fibrosis Airway Epithelial Monolayers
L Pizurki, MA Morris, M Chanson, M Solomon, A Pavirani, I Bouchardy, S Suter |
The American Journal of Pathology | 2000 |
Heterotopic Ossification of Degenerating Rat Skeletal Muscle Induced by Adenovirus-Mediated Transfer of Bone Morphogenetic Protein-2 Gene
K Gonda, T Nakaoka, K Yoshimura, Y Otawara-Hamamoto, K Harrii |
Journal of Bone and Mineral Research | 2000 |
Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization
K Spilsbury, KL Garrett, WY Shen, IJ Constable, PE Rakoczy |
The American Journal of Pathology | 2000 |
The role of IL-6 in the inflammatory and humoral response to adenoviral vectors
K Benihoud, B Salone, S Esselin, P Opolon, V Poli, MD Giovine, M Perricaudet, I Saggio |
The Journal of Gene Medicine | 2000 |
Heat Shock Protein 70 Is Required for the Survival of Cancer Cells
J Nylandsted, K Brand, M Jäättelä |
Annals of the New York Academy of Sciences | 2000 |
Overexpression of Glutathione Peroxidase Increases the Resistance of Neuronal Cells to Aβ-Mediated Neurotoxicity
M Barkats, S Millecamps, P Abrioux, MC Geoffroy, J Mallet |
Journal of Neurochemistry | 2000 |
Gene transfer to urethral strictures in rabbits: a preliminary report
P Meria, M Anidjar, JP Brouland, P Teillac, P Berthon, O Cussenot |
BJU International | 2000 |
Optimization of Adenoviral Vector-Mediated Gene Transfer to Pulmonary Arteries in Newborn Swine
S Badran, SK Schachtner, HS Baldwin, JJ Rome |
Human Gene Therapy | 2000 |
Comparative in Vivo Approaches for Selective Adenovirus-Mediated Gene Delivery to the Placenta
A Xing, P Boileau, M Cauzac, JC Challier, J Girard, SH Mouzon |
Human Gene Therapy | 2000 |
Modulation of Starling Forces and Muscle Fiber Maturity Permits Adenovirus-Mediated Gene Transfer to Adult Dystrophic (mdx) Mice by the Intravascular Route
WK Cho, S Ebihara, J Nalbantoglu, R Gilbert, B Massie, P Holland, G Karpati, BJ Petrof |
Human Gene Therapy | 2000 |
A bcl-xS adenovirus selectively induces apoptosis in transformed cells compared to normal mammary cells
VN Sumantran, DS Lee, KM Ignatoski, SP Ethier, MS Wicha |
Neoplasia (New York, N.Y.) | 2000 |
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
J Nylandsted, M Rohde, K Brand, L Bastholm, F Elling, M Jäättelä |
Proceedings of the National Academy of Sciences | 2000 |
Noninvasive measurement of gene expression in skeletal muscle
G Walter, ER Barton, HL Sweeney |
Proceedings of the National Academy of Sciences | 2000 |
Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer
A Ghodsi, C Stein, T Derksen, I Martins, RD Anderson, BL Davidson |
Experimental Neurology | 2000 |
Systemic Administration of HVJ Viral Coat–Liposome Complex Containing Human Insulin Vector Decreases Glucose Level in Diabetic Mouse: A Model of Gene Therapy
R Morishita, GH Gibbons, Y Kaneda, T Ogihara, VJ Dzau |
Biochemical and Biophysical Research Communications | 2000 |
Expression of Palmitoyl Protein Thioesterase in Neurons
O Heinonen, A Kyttälä, E Lehmus, T Paunio, L Peltonen, A Jalanko |
Molecular Genetics and Metabolism | 2000 |
Structural and Functional Characterizations of the 5′-Flanking Region of the Mouse Glucagon Receptor Gene: Comparison with the Rat Gene
A Geiger, JF Decaux, R Burcelin, AL Cam, G Salazar, MJ Charron, J Girard, A Kervran |
Biochemical and Biophysical Research Communications | 2000 |
Prospects for gene therapy for inherited cardiomyopathies
NE Bowles, K Bowles, JA Towbin |
Progress in Pediatric Cardiology | 2000 |
The Role of Vascular Endothelial Growth Factor (VEGF) in Abnormal Vascular Changes in the Adult Rat Eye
MJ Yu, WY Shen, MC Lai, IJ Constable, JM Papadimitriou, PE Rakoczy |
Growth Factors | 2000 |
DNA/Dendrimer Complexes Mediate Gene Transfer into Murine Cardiac Transplants ex Vivo
Y Wang, P Boros, J Liu, L Qin, Y Bai, AU Bielinska, JF Kukowska-Latallo, JR Baker, JS Bromberg |
Molecular Therapy | 2000 |
Effect of percutaneous adenovirus-mediated Gax gene delivery to the arterial wall in double-injured atheromatous stented rabbit iliac arteries
L Maillard, EV Belle, FO Tio, A Rivard, M Kearney, D Branellec, PG Steg, JM Isner, K Walsh |
Gene Therapy | 2000 |
Direct intra-cardiomuscular transfer of β2-adrenergic receptor gene augments cardiac output in cardiomyopathic hamsters
K Tomiyasu, Y Oda, M Nomura, E Satoh, S Fushiki, J Imanishi, M Kondo, O Mazda |
Gene Therapy | 2000 |
Gene transfer of recombinant endothelial nitric oxide synthase to liver in vivo and in vitro
V Shah, AF Chen, S Cao, H Hendrickson, D Weiler, L Smith, J Yao, ZS Katusic |
AJP Gastrointestinal and Liver Physiology | 2000 |
Activation of heat-shock response by an adenovirus is essential for virus replication
JB Glotzer, M Saltik, S Chiocca, AI Michou, P Moseley, M Cotten |
Nature | 2000 |
Suppression of pulmonary metastasis using adenovirally motility related protein-1 (MRP-1/CD9) gene delivery
M Miyake, H Inufusa, M Adachi, H Ishida, H Hashida, T Tokuhara, Y Kakehi |
Oncogene | 2000 |
Analysis of Muscle Creatine Kinase Regulatory Elements in Recombinant Adenoviral Vectors
MA Hauser, A Robinson, D Hartigan-O'Connor, DA Williams-Gregory, JN Buskin, S Apone, CJ Kirk, S Hardy, SD Hauschka, JS Chamberlain |
Molecular Therapy | 2000 |
Stable Transduction of Actively Dividing Cells via a Novel Adenoviral/Episomal Vector
H Leblois, C Roche, ND Falco, C Orsini, P Yeh, M Perricaudet |
Molecular Therapy | 2000 |
Immunolocalization and Adenoviral Vector-mediated Manganese Superoxide Dismutase Gene Transfer to Experimental Oral Tumors
EW Lam, HM Hammad, R Zwacka, CJ Darby, KR Baumgardner, BL Davidson, TD Oberley, JF Engelhardt, LW Oberley |
Journal of dental research | 2000 |
In Vivo Adenovirus-Mediated Suicide Gene Therapy of Orthotopic Bladder Cancer
MA Sutton, CT Freund, SA Berkman, TD Dang, MW Kattan, TM Wheeler, DR Rowley, SP Lemer |
Molecular Therapy | 2000 |
In Vivo Transduction of Cerebellar Purkinje Cells Using Adeno-Associated Virus Vectors
WF Kaemmerer, RG Reddy, CA Warlick, SD Hartung, RS McIvor, WC Low |
Molecular Therapy | 2000 |
High-Efficiency, Long-Term Cardiac Expression of Foreign Genes in Living Mouse Embryos and Neonates
G Christensen, S Minamisawa, PJ Gruber, Y Wang, KR Chien |
Circulation | 2000 |
Clinical Trials in Coronary Angiogenesis: Issues, Problems, Consensus: An Expert Panel Summary
M Simons, RO Bonow, NA Chronos, DJ Cohen, FJ Giordano, HK Hammond, RJ Laham, W Li, M Pike, FW Sellke, TJ Stegmann, JE Udelson, TK Rosengart |
Circulation | 2000 |
Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuronopathy
T Bordet, H Schmalbruch, B Pettmann, A Hagege, L Castelnau-Ptakhine, A Kahn, G Haase |
Journal of Clinical Investigation | 1999 |
Regulation of smooth muscle cell migration and integrin expression by the Gax transcription factor
B Witzenbichler, Y Kureishi, Z Luo, AL Roux, D Branellec, K Walsh |
Journal of Clinical Investigation | 1999 |
Systemic Delivery of Antiangiogenic Adenovirus AdmATF Induces Liver Resistance to Metastasis and Prolongs Survival of Mice
H Li, F Griscelli, F Lindenmeyer, P Opolon, LQ Sun, E Connault, J Soria, C Soria, M Perricaudet, P Yeh |
Human Gene Therapy | 1999 |
URETERAL GENE TRANSFER TO PORCINE INDUCED STRICTURES USING ENDOUROLOGIC DELIVERY OF AN ADENOVIRAL VECTOR
M Anidjar, P Mongiat-Artus, JP Brouland, B Cochand-Priollet, P Teillac, AL Duc, P Berthon, O Cussenot |
The Journal of Urology | 1999 |
Molecular targets of gene therapy
DK Das, RM Engelman, N Maulik, JA Rousou, JE Flack, DW Deaton |
The Annals of Thoracic Surgery | 1999 |
Adenovirus-mediated gene transfer to the peritoneum and hepatic parenchyma of fetal mice in utero
GS Lipshutz, L Flebbe-Rehwaldt, KM Gaensler |
Surgery | 1999 |
Gene therapy for Parkinson’s disease: review and update
UJ Kang, DM Frim |
Expert Opinion on Investigational Drugs | 1999 |
Brain-Derived Neurotrophic Factor-Mediated Protection of Striatal Neurons in an Excitotoxic Rat Model of Huntington's Disease, as Demonstrated by Adenoviral Gene Transfer
AP Bemelmans, P Horellou, L Pradier, I Brunet, P Colin, J Mallet |
Human Gene Therapy | 1999 |
Solvoplex: A New Type of Synthetic Vector for Intrapulmonary Gene Delivery
K Schughart, R Bischoff, UB Rasmussen, DA Hadji, F Perraud, N Accart, O Boussif, N Silvestre, Y Cordier, A Pavirani, HV Kolbe |
Human Gene Therapy | 1999 |
A commentary on glial cell line-derived neurotrophic factor (GDNF) From a glial secreted molecule to gene therapy
M Bohn |
Biochemical Pharmacology | 1999 |
Adenovirus-mediated introduction of DNA into pig sperm and offspring
L Farre, T Rigau, T Mogas, M Garc�a-Rocha, M Canal, AM Gomez-Foix, JE Rodr�guez-Gil |
Molecular Reproduction and Development | 1999 |
Gene Transfer And Models Of Gene Therapy For The Myocardium
MY Alexander, KA Webster, PH McDonald, HM Prentice |
Clinical and Experimental Pharmacology and Physiology | 1999 |
Therapeutic benefit of ciliary neurotrophic factor in progressive motor neuronopathy depends on the route of delivery
G Haase, B Pettmann, T Bordet, P Villa, E Vigne, H Schmalbruch, A Kahn |
Annals of Neurology | 1999 |
Angiogenic growth factor release system for in vivo tissue engineering: a trial of bone marrow transplantation into ischemic myocardium
Y Noishiki, Y Ichikawa, I Yamazaki, M Mo, K Yamamoto, T Kosuge, K Takahashi, Y Yamane |
Journal of Artificial Organs | 1999 |
Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B
H Schneider, S Adebakin, M Themis, T Cook, AM Douar, A Pavirani, C Coutelle |
The Journal of Gene Medicine | 1999 |
Adenovirus-mediated suicide gene therapy in an in vitro model of reactive gliosis
S Audouy, J Mallet, A Privat, MG Ribotta |
Glia | 1999 |
A MAGE-A4 peptide presented by HLA-A2 is recognized by cytolytic T lymphocytes
MT Duffour, P Chaux, C Lurquin, G Cornelis, T Boon, PV der Bruggen |
European Journal of Immunology | 1999 |
Adenovirus vectors for gene delivery
K Benihoud |
Current Opinion in Biotechnology | 1999 |
Effective gene transfer oflacZ andP0 into Schwann cells of P0-deficient mice
V Gu�nard, B Schweitzer, E Flechsig, S Hemmi, R Martini, U Suter, M Schachner |
Glia | 1999 |
Cationic Lipids and Polymers Are Able to Enhance Adenoviral Infection of Cultured Mouse Myotubes
E Dodds, TA Piper, SJ Murphy, G Dickson |
Journal of Neurochemistry | 1999 |
Human Tissue Kallikrein Attenuates Hypertension and Secretes into Circulation and Urine After Intramuscular Gene Delivery in Hypertensive Rats
JJ Zhang, C Wang, KF Lin, L Chao, J Chao |
Clinical and Experimental Hypertension | 1999 |
Novel Human Gene Transfer Vectors: Evaluation of Wild-Type and Recombinant Animal Adenoviruses in Human-Derived Cells
UB Rasmussen, M Benchaibi, V Meyer, Y Schlesinger, K Schughart |
Human Gene Therapy | 1999 |
A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells
T Dorai, H Perlman, K Walsh, A Shabsigh, ET Goluboff, CA Olsson, R Buttyan |
International Journal of Cancer | 1999 |
Fiberless recombinant adenoviruses: virus maturation and infectivity in the absence of fiber
V Legrand, D Spehner, Y Schlesinger, N Settelen, A Pavirani, M Mehtali |
Journal of virology | 1999 |
Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro
K Aoki, C Barker, X Danthinne, MJ Imperiale, GJ Nabel |
Molecular Medicine | 1999 |
Systemic correction of the muscle disorder glycogen storage disease type II after hepatic targeting of a modified adenovirus vector encoding human acid-alpha-glucosidase
A Amalfitano, AJ McVie-Wylie, H Hu, TL Dawson, N Raben, P Plotz, YT Chen |
Proceedings of the National Academy of Sciences | 1999 |
Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin
A Loregian, E Papini, B Satin, HS Marsden, TR Hirst, G Palù |
Proceedings of the National Academy of Sciences | 1999 |
Gene transfection of beta 2–adrenergic receptor into the normal rat heart enhances cardiac response to beta-adrenergic agonist
Y Kawahira, Y Sawa, M Nishimura, S Sakakida, H Ueda, Y Kaneda, H Matsuda |
The Journal of Thoracic and Cardiovascular Surgery | 1999 |
Normal Perinatal Rise in Serum Cholesterol Is Inhibited by Hepatic Delivery of Adenoviral Vector Expressing Apolipoprotein B mRNA Editing Enzyme (Apobec1) in Rabbits
Y Wu, BB Teng, ML Brandt, PA Piedra, J Liu, L Chan |
Journal of Surgical Research | 1999 |
Adenoviral Gene Therapy of the Tay-Sachs Disease in Hexosaminidase A-Deficient Knock-Out Mice
JE Guidotti, A Mignon, G Haase, C Caillaud, N McDonell, A Kahn, L Poenaru |
Human Molecular Genetics | 1999 |
Ex Vivo Cell Therapy
RE Nordon, K Schindhelm |
Ex Vivo Cell Therapy | 1999 |
Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis
A Stempien-Otero, A Karsan, CJ Cornejo, H Xiang, T Eunson, RS Morrison, M Kay, R Winn, J Harlan |
The Journal of biological chemistry | 1999 |
Gene Expression Systems
R Abbud, JH Nilson |
Gene Expression Systems | 1999 |
Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia
J Herz, RD Gerard |
Diabetes | 1999 |
Age-dependent impairment of angiogenesis
JM Isner, I Baumgartner, G Rauh, R Schainfeld, R Blair, O Manor, S Razvi, JF Symes |
Circulation | 1999 |
Gene transfer into canine myoblasts
S Braun, C Thioudellet, F Perraud, C Escriou, MC Claudepierre, H Homann, M Lusky, M Mehtali, R Bischoff, A Pavirani |
Cytotechnology | 1999 |
A Cystic Fibrosis Tracheal Gland Cell Line, CF-KM4: Correction by Adenovirus-Mediated CFTR Gene Transfer
W Kammouni, B Moreau, F Becq, A Saleh, A Pavirani, C Figarella, MD Merten |
American journal of respiratory cell and molecular biology | 1999 |
Systemic correction of the muscle disorder glycogen storage disease type II after hepatic targeting of a modified adenovirus vector encoding human acid- -glucosidase
A Amalfitano, AJ McVie-Wylie, H Hu, TL Dawson, N Raben, P Plotz, YT Chen |
Proceedings of the National Academy of Sciences | 1999 |
A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors
O Corti, O Sabaté, P Horellou, P Colin, S Dumas, D Buchet, MH Buc-Caron, J Mallet |
Nature Biotechnology | 1999 |
NF-κB Activation Is Required for Human Endothelial Survival during Exposure to Tumor Necrosis Factor-α but Not to Interleukin-1β or Lipopolysaccharide
K Zen, A Karsan, A Stempien-Otero, E Yee, J Tupper, X Li, T Eunson, MA Kay, CB Wilson, RK Winn, JM Harlan |
The Journal of biological chemistry | 1999 |
Shear Stress Stimulation of p130 cas Tyrosine Phosphorylation Requires Calcium-dependent c-Src Activation
M Okuda, M Takahashi, J Suero, CE Murry, O Traub, H Kawakatsu, BC Berk |
The Journal of biological chemistry | 1999 |
Pulmonary inflammation associated with repeated, prenatal exposure to an E1, E3-deleted adenoviral vector in sheep
HS Iwamoto, BC Trapnell, CJ McConnell, C Daugherty, JA Whitsett |
Gene Therapy | 1999 |
Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein
M Themis, H Schneider, T Kiserud, T Cook, S Adebakin, S Jezzard, S Forbes, M Hanson, A Pavirani, C Rodeck, C Coutelle |
Gene Therapy | 1999 |
Temporally regulated expression patterns following in utero adenovirus-mediated gene transfer
SK Schachtner, CA Buck, JM Bergelson, HS Baldwin |
Gene Therapy | 1999 |
Neuron-restrictive silencer elements mediate neuron specificity of adenoviral gene expression
S Millecamps, H Kiefer, V Navarro, MC Geoffroy, JJ Robert, F Finiels, J Mallet, M Barkats |
Nature Biotechnology | 1999 |
Angiogenesis induced in muscle by a recombinant adenovirus expressing functional isoforms of basic fibroblast growth factor
C Garcia-Martinez, P Opolon, V Trochon, C Chianale, K Musset, H Lu, M Abitbol, M Perricaudet, T Ragot |
Gene Therapy | 1999 |
Intrauterine gene transfer: gestational stage-specific gene delivery in mice
A Türkay, TL Saunders, K Kurachi |
Gene Therapy | 1999 |
Adenovirus-mediated delivery of the Gax transcription factor to rat carotid arteries inhibits smooth muscle proliferation and induces apoptosis
H Perlman, Z Luo, K Krasinski, AL Roux, A Mahfoudi, RC Smith, D Branellec, K Walsh |
Gene Therapy | 1999 |
A model for long-term transgene expression in spinal cord regeneration studies
MT OLeary, HM Charlton |
Gene Therapy | 1999 |
Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and ΔE1B adenovirus replication in human cells
WT Steegenga, N Riteco, JL Bos |
Oncogene | 1999 |
Induction of apoptosis and G2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection
K Brand, R Klocke, A Poβling, D Paul, M Strauss |
Gene Therapy | 1999 |
Gene delivery to the myocardium by intrapericardial injection
Y Fromes, A Salmon, X Wang, H Collin, A Rouche, A Hagège, K Schwartz, MY Fiszman |
Gene Therapy | 1999 |
Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo
JC Jiménez-Chillarón, CB Newgard, AM GÓMEZ-FOIX |
The FASEB Journal | 1999 |
Somatic Gene Transfer of Human ApoA-I Inhibits Atherosclerosis Progression in Mouse Models
P Benoit, F Emmanuel, JM Caillaud, L Bassinet, G Castro, P Gallix, JC Fruchart, D Branellec, P Denèfle, N Duverger |
Circulation | 1999 |
Adenovirus-Mediated Overexpression of Tissue Inhibitor of Metalloproteinase-1 Reduces Atherosclerotic Lesions in Apolipoprotein E–Deficient Mice
M Rouis, C Adamy, N Duverger, P Lesnik, P Horellou, M Moreau, F Emmanuel, JM Caillaud, PM Laplaud, C Dachet, MJ Chapman |
Circulation | 1999 |
Efficient gene transfer and long-term expression in neurons using a recombinant adenovirus with a neuron-specific promoter
V Navarro, S Millecamps, MC Geoffroy, JJ Robert, A Valin, J Mallet, GL Salle |
Gene Therapy | 1999 |
Contemporary Concepts in Cardiology
R Gorlin, G Dangas, PK Toutouzas, MM Konstadoulakis |
1999 | |
New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet
T Ochiya, Y Takahama, S Nagahara, Y Sumita, A Hisada, H Itoh, Y Nagai, M Terada |
Nature Medicine | 1999 |
Cardiovascular Specific Gene Expression
PA Doevendans, RS Reneman, M van Bilsen |
1999 | |
Biology of the Arterial Wall
BI Levy, A Tedgui |
1999 | |
Direct Myocardial Revascularization: History, Methodology, Technology
P Whittaker, GS Abela |
1999 | |
ADENOVIRAL VECTORS FOR PROTEIN EXPRESSION
Von Seggern DJ, Nemerow GR |
Gene Expression Systems | 1999 |
A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance
R Josien, P Douillard, C Guillot, M Müschen, I Anegon, J Chetritt, S Menoret, C Vignes, JP Soulillou, MC Cuturi |
Journal of Clinical Investigation | 1998 |
Extensiveβ-Glucuronidase Activity in Murine Central Nervous System after Adenovirus-Mediated Gene Transfer to Brain
A Ghodsi, C Stein, T Derksen, G Yang, RD Anderson, BL Davidson |
Human Gene Therapy | 1998 |
Lipofectamine and Related Cationic Lipids Strongly Improve Adenoviral Infection Efficiency of Primitive Human Hematopoietic Cells
T Byk, H Haddada, W Vainchenker, F Louache |
Human Gene Therapy | 1998 |
Effects of Poloxamer 407 on Transfection Time and Percutaneous Adenovirus-Mediated Gene Transfer in Native and Stented Vessels
E Belle, L Maillard, A Rivard, JE Fabre, T Couffinhal, M Kearney, D Branellec, LJ Feldman, K Walsh, JM Isner |
Human Gene Therapy | 1998 |
Gene Therapy with Bilirubin-UDP-Glucuronosyltransferase in the Gunn Rat Model of Crigler-Najjar Syndrome Type 1
Q Li, SS Murphree, SS Willer, R Bolli, BA French |
Human Gene Therapy | 1998 |
Gene Transfer Into the Donor Heart During Cold Preservation for Heart Transplantation
SG MD, KN MD, ST MD, KN MD, SK MD |
The Annals of Thoracic Surgery | 1998 |
Gene transfer to schwann cells after peripheral nerve injury: A delivery system for therapeutic agents
J S�rensen, G Haase, C Krarup, H Gilgenkrantz, A Kahn, H Schmalbruch |
Annals of Neurology | 1998 |
Induction of DNA fragmentation and HSP72 immunoreactivity by adenovirus-mediated gene transfer in normal gerbil hippocampus and ventricle
H Kitagawa, Y Setoguchi, Y Fukuchi, Y Mitsumoto, N Koga, T Mori, K Abe |
Journal of Neuroscience Research | 1998 |
Ex Vivo and In Vivo Adenovirus-Mediated Gene Therapy Strategies Induce a Systemic Anti-Tumor Immune Defence in the B16 Melanoma Model
B Bonnekoh, DA Greenhalgh, SH Chen, A Block, SS Rich, T Krieg, SL Woo, DR Roop |
Journal of Investigative Dermatology | 1998 |
Heart-Specific Targeting ofβ-Galactosidase by the Ventricle-Specific Cardiac Myosin Light Chain 2 Promoter Using Adenovirus Vectors
F Griscelli, P Gilardi-Hebenstreit, N Hanania, WM Franz, P Opolon, M Perricaudet, T Ragot |
Human Gene Therapy | 1998 |
Sustained Expression of High Levels of Human Factor IX from Human Cells Implanted within an Immunoisolation Device into Athymic Rodents
J Brauker, GH Frost, V Dwarki, T Nijjar, R Chin, V Carr-Brendel, C Jasunas, D Hodgett, W Stone, LK Cohen, RC Johnson |
Human Gene Therapy | 1998 |
Novel Tools for Production and Purification of Recombinant Adenoassociated Virus Vectors
D Grimm, A Kern, K Rittner, JA Kleinschmidt |
Human Gene Therapy | 1998 |
Anti-Adenovirus Immune Responses in Rats Are Enhanced by Interleukin 4 but Not Interleukin 10 Produced by Recombinant Adenovirus
A David, H Coupel-Clauce, J Chetritt, L Tesson, A Cassard, B Charreau, JP Soulillou, I Anegon |
Human Gene Therapy | 1998 |
Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity
H Perlman, M Sata, AL Roux, TW Sedlak, D Branellec, K Walsh |
The EMBO Journal | 1998 |
Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases
E Li, D Stupack, GM Bokoch, GR Nemerow |
Journal of virology | 1998 |
Transient inhibition of CD28 and CD40 ligand interactions prolongs adenovirus-mediated transgene expression in the lung and facilitates expression after secondary vector administration
CB Wilson, LJ Embree, D Schowalter, R Albert, A Aruffo, D Hollenbaugh, P Linsley, MA Kay |
Journal of virology | 1998 |
The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells
L Zhang, U Sankar, DJ Lampe, HM Robertson, FL Graham |
Nucleic Acids Research | 1998 |
Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest
F Griscelli, H Li, A Bennaceur-Griscelli, J Soria, P Opolon, C Soria, M Perricaudet, P Yeh, H Lu |
Proceedings of the National Academy of Sciences | 1998 |
Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver
K Jooss, HC Ertl, JM Wilson |
Journal of virology | 1998 |
Immune response to recombinant capsid proteins of adenovirus in humans: antifiber and anti-penton base antibodies have a synergistic effect on neutralizing activity
H Gahéry-Ségard, F Farace, D Godfrin, J Gaston, R Lengagne, T Tursz, P Boulanger, JG Guillet |
Journal of virology | 1998 |
In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted
M Lusky, M Christ, K Rittner, A Dieterle, D Dreyer, B Mourot, H Schultz, F Stoeckel, A Pavirani, M Mehtali |
Journal of virology | 1998 |
A simplified system for generating recombinant adenoviruses
TC He, S Zhou, LT da Costa, J Yu, KW Kinzler, B Vogelstein |
Proceedings of the National Academy of Sciences | 1998 |
Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted
A Amalfitano, MA Hauser, H Hu, D Serra, CR Begy, JS Chamberlain |
Journal of virology | 1998 |
Adenoviral gene transfer to spinal cord neurons: intrathecal vs. intraparenchymal administration
AJ Mannes, RM Caudle, BC O'Connell, MJ Iadarola |
Brain Research | 1998 |
Adenovirus-Mediated Transfer of the Acid -Glucosidase Gene into Fibroblasts, Myoblasts and Myotubes from Patients with Glycogen Storage Disease Type II Leads to High Level Expression of Enzyme and Corrects Glycogen Accumulation
MP Nicolino, JP Puech, EJ Kremer, AJ Reuser, C Mbebi, M Verdiere-Sahuque, A Kahn, L Poenaru |
Human Molecular Genetics | 1998 |
Angiostatin gene transfer: Inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest
F Griscelli, H Li, A Bennaceur-Griscelli, J Soria, P Opolon, C Soria, M Perricaudet, P Yeh, H Lu |
Proceedings of the National Academy of Sciences | 1998 |
Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion
C A Mack, C J Magovern, K T Budenbender, S R Patel, E A Schwarz, P Zanzonico, B Ferris, T Sanborn, P Isom, B Ferris, T Sanborn, O W Isom, R G Crystal, T K Rosengart |
Journal of Vascular Surgery | 1998 |
Cells of the Neuronal Lineage Play a Major Role in the Generation of Amyloid Precursor Fragments in Gelsolin-related Amyloidosis
T Paunio, H Kangas, O Heinonen, MH Buc-Caron, JJ Robert, S Kaasinen, I Julkunen, J Mallet, L Peltonen |
The Journal of biological chemistry | 1998 |
Cell polarity, phagocytosis and viral gene transfer in cultured human retinal pigment epithelial cells
L Cruz, T Robertson, MO Hall, IJ Constable, PE Rakoczy |
Current Eye Research | 1998 |
Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: Preliminary clinical results
JM Isner, I Baumgartner, G Rauh, R Schainfeld, R Blair, O Manor, S Razvi, JF Symes |
Circulation | 1998 |
GATA-6 Induces p21 Cip1 Expression and G 1 Cell Cycle Arrest
H Perlman, E Suzuki, M Simonson, RC Smith, K Walsh |
The Journal of biological chemistry | 1998 |
The Long Term Adenoviral Expression of the Human Amyloid Precursor Protein Shows Different Secretase Activities in Rat Cortical Neurons and Astrocytes
AF Macq, C Czech, R Essalmani, JP Brion, A Maron, L Mercken, L Pradier, JN Octave |
The Journal of biological chemistry | 1998 |
Constitutive Expression of phVEGF 165 After Intramuscular Gene Transfer Promotes Collateral Vessel Development in Patients With Critical Limb Ischemia
I Baumgartner, A Pieczek, O Manor, R Blair, M Kearney, K Walsh, JM Isner |
Circulation | 1998 |
The Ischemic Heart
S Mochizuki, N Takeda, M Nagano, NS Dhalla |
1998 | |
An in Vivo Model for Elucidation of the Mechanism of Tumor Necrosis Factor-α (TNF-α)-Induced Insulin Resistance: Evidence for Differential Regulation of Insulin Signaling by TNF-α
AT Cheung, D Ree, JK Kolls, J Fuselier, DH Coy, M Bryer-Ash |
Endocrinology | 1998 |
Immunotherapy for Medullary Thyroid Carcinoma by a Replication-Defective Adenovirus Transducing Murine Interleukin-2
R Zhang, K Minemura, LJ Groot |
Endocrinology | 1998 |
Adenovirus Endocytosis via α v Integrins Requires Phosphoinositide-3-OH Kinase
E Li, D Stupack, R Klemke, DA Cheresh, GR Nemerow |
Journal of virology | 1998 |
Efficient, Repeated Adenovirus-Mediated Gene Transfer in Mice Lacking both Tumor Necrosis Factor Alpha and Lymphotoxin α
K Benihoud, I Saggio, P Opolon, B Salone, F Amiot, E Connault, C Chianale, F Dautry, P Yeh, M Perricaudet |
Journal of virology | 1998 |
Developmental remodeling and shortening of the cardiac outflow tract involves myocyte programmed cell death
M Watanabe, A Choudhry, M Berlan, A Singal, E Siwik, S Mohr, SA Fisher |
Development (Cambridge, England) | 1998 |
Adenovirus mediated gene therapy in a glioblastoma vaccine model; specific antitumor immunity and abrogation of immunosuppression
A M Donson, N K Foreman |
Journal of Neuro-Oncology | 1998 |
Prevention of bleomycin-induced pulmonary fibrosis after adenovirus-mediated transfer of the bacterial bleomycin resistance gene
PL Tran, J Weinbach, P Opolon, G Linares-Cruz, JP Reynes, A Grégoire, E Kremer, H Durand, M Perricaudet |
Journal of Clinical Investigation | 1997 |
In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat
K Suzuki, Y Sawa, Y Kaneda, H Ichikawa, R Shirakura, H Matsuda |
Journal of Clinical Investigation | 1997 |
Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo
R Agah, PA Frenkel, BA French, LH Michael, PA Overbeek, MD Schneider |
Journal of Clinical Investigation | 1997 |
Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication
T Schöneberg, V Sandig, J Wess, T Gudermann, G Schultz |
Journal of Clinical Investigation | 1997 |
Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products
H Gahéry-Ségard, V Molinier-Frenkel, CL Boulaire, P Saulnier, P Opolon, R Lengagne, E Gautier, AL Cesne, L Zitvogel, A Venet, C Schatz, M Courtney, TL Chevalier, T Tursz, JG Guillet, F Farace |
Journal of Clinical Investigation | 1997 |
Trypanosoma cruzi infection does not impair major histocompatibility complex class I presentation of antigen to cytotoxic T lymphocytes
FS Buckner, BT Wipke, WC van Voorhis |
European Journal of Immunology | 1997 |
Retroviral Transfer of Acidα-Glucosidase cDNA to Enzyme-Deficient Myoblasts Results in Phenotypic Spread of the Genotypic Correction by Both Secretion and Fusion
JZ Zaretsky, F Candotti, C Boerkoel, EM Adams, JW Yewdell, RM Blaese, PH Plotz |
Human Gene Therapy | 1997 |
Vasomotor Dysfunction Early after Exposure of Normal Rabbit Arteries to an Adenoviral Vector
A Lafont, G Loirand, P Pacaud, F Vilde, P Lemarchand, D Escande |
Human Gene Therapy | 1997 |
Induction of a cAMP–Stimulated Chloride Secretion in Regenerating Poorly Differentiated Airway Epithelial Cells by Adenovirus-Mediated CFTR Gene Transfer
F Dupuit, T Chinet, JM Zahm, D Pierrot, J Hinnrasky, H Kaplan, N Bonnet, E Puchelle |
Human Gene Therapy | 1997 |
Adenoviral preterminal protein stabilizes mini-adenoviral genomes in vitro and in vivo
A Lieber, CY He, MA Kay |
Nature Biotechnology | 1997 |
In vivo gene transfer and overexpression of focal adhesion kinase (pp125 FAK) mediated by recombinant adenovirus-induced tendon adhesion formation and epitenon cell change
J Lou, H Kubota, S Hotokezaka, FJ Ludwig, PR Manske |
Journal of Orthopaedic Research | 1997 |
Adenovirus-Mediated Gene Transfer into Isolated Mouse Adult Pancreatic Islets: Normalβ-Cell Function Despite Induction of an Anti-Adenovirus Immune Response
J Sigalla, A David, I Anegon, M Fiche, JM Huvelin, F Boeffard, A Cassard, JP Soulillou, BL Mauff |
Human Gene Therapy | 1997 |
Functional Consequences of Adenovirus-Mediated Murine Pancreatic Gene Transfer
SJ McClane, TE Hamilton, CV Burke, SE Raper |
Human Gene Therapy | 1997 |
Two-Step Delivery of Retroviruses to Postmitotic, Terminally Differentiated Cells
M Ito, L Kedes |
Human Gene Therapy | 1997 |
Modulation of the Specificity and Activity of a Cellular Promoter in an Adenoviral Vector
Q Shi, Y Wang, R Worton |
Human Gene Therapy | 1997 |
Efficient Adenovirus-Mediated Ectopic Gene Expression of Human Lipoprotein Lipase in Human Hepatic (HepG2) Cells
G Liu, KJ Excoffon, P Benoit, DG Ginzinger, L Miao, E Ehrenborg, N Duverger, PP Denefle, MR Hayden, ME Lewis |
Human Gene Therapy | 1997 |
Strategic gene transfer into the kidney: Current status and prospects
M Kitamura |
Clinical and Experimental Nephrology | 1997 |
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
G Haase, P Kennel, B Pettmann, E Vigne, S Akli, F Revah, H Schmalbruch, A Kahn |
Nature Medicine | 1997 |
In vivo adenovirus-mediated gene transfer and the expression in ischemic and reperfused rat brain
K Abe, Y Setoguchi, T Hayashi, Y Itoyama |
Brain Research | 1997 |
Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons
C Gravel, R Götz, A Lorrain, M Sendtner |
Nature Medicine | 1997 |
Prevention of motoneuron death by adenovirus-mediated neurotrophic factors
MG Ribotta, F Revah, L Pradier, I Loquet, J Mallet, A Privat |
Journal of Neuroscience Research | 1997 |
Inhibition of the growth of pre-established subcutaneous tumor nodules of human prostate cancer cells by single injection of the recombinant adenovirus p53 expression vector
K Asgari, IA Sesterhenn, DG McLeod, K Cowan, JW Moul, P Seth, S Srivastava |
International Journal of Cancer | 1997 |
Efficient introduction of genes into human ovarian surface epithelium
EH Leung, BR Davies, PC Leung, GT Chen, CD Roskelley, N Auersperg |
In Vitro Cellular & Developmental Biology - Animal | 1997 |
Gene transfer into mouse embryonic stem cell-derived cardiac myocytes mediated by recombinant adenovirus
EM Rust, MV Westfall, LC Samuelson, JM Metzger |
In Vitro Cellular & Developmental Biology - Animal | 1997 |
Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase
M Barkats, N Nakao, EM Grasbon-Frodl, A Bilang-Bleuel, F Revah, J Mallet, P Brundin |
Neuroscience | 1997 |
Transductional Efficacy and Safety of an Intraperitoneally Delivered Adenovirus Encoding an Anti-erbB-2 Intracellular Single-Chain Antibody for Ovarian Cancer Gene Therapy
J Deshane, GP Siegal, M Wang, M Wright, RP Bucy, RD Alvarez, DT Curiel |
Gynecologic Oncology | 1997 |
Adenoviras-mediated expression of human CD59 on xenogeneic endothelial cells: Protection against human complement-mediated lysis and induction of cellular activation by adenoviral transduction
B Charreau, L Tesson, A David, A Cassard, B Quantin, A Pavirani, JP Soulillou, I Anegon |
Xenotransplantation | 1997 |
Enhancement of Humoral Immunity to SIVenv Following Simultaneous Inoculation of Mice by Three Recombinant Adenoviruses Encoding SIVenv/Poliovirus Chimeras, Tat and Rev
N Chenciner, V Randrianarison-Jewtoukoff, F Delpeyroux, N Hanania, LP Martins, LS Perricaudet, M Perricaudet, S Wain-Hobson |
AIDS Research and Human Retroviruses | 1997 |
Histochemical Staining FollowingLacZGene Transfer Underestimates Transfection Efficiency
T Couffinhal, M Kearney, A Sullivan, M Silver, Y Tsurumi, JM Isner |
Human Gene Therapy | 1997 |
Promoter Attenuation in Gene Therapy: Interferon-γand Tumor Necrosis Factor-αInhibit Transgene Expression
L Qin, Y Ding, DR Pahud, E Chang, MJ Imperiale, JS Bromberg |
Human Gene Therapy | 1997 |
Characterization of the Immune Response After Local Delivery of Recombinant Adenovirus in Murine Pancreas and Successful Strategies for Readministration
SJ McClane, N Chirmule, CV Burke, SE Raper |
Human Gene Therapy | 1997 |
Mechanism of adenovirus improvement of cationic liposome-mediated gene transfer
C Meunier-Durmort, R Picart, T Ragot, M Perricaudet, B Hainque, C Forest |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1997 |
Adenoviral vectors: development and application
WW Zhang |
Expert Opinion on Investigational Drugs | 1997 |
Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo
N Oudrhiri, JP Vigneron, M Peuchmaur, T Leclerc, JM Lehn, P Lehn |
Proceedings of the National Academy of Sciences | 1997 |
Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
A Bilang-Bleuel, F Revah, P Colin, I Locquet, JJ Robert, J Mallet, P Horellou |
Proceedings of the National Academy of Sciences | 1997 |
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses
JF Dedieu, E Vigne, C Torrent, C Jullien, I Mahfouz, JM Caillaud, N Aubailly, C Orsini, JM Guillaume, P Opolon, P Delaere, M Perricaudet, P Yeh |
Journal of virology | 1997 |
Cre-mediated somatic site-specific recombination in mice
K Akagi, V Sandig, M Vooijs, MV der Valk, M Giovannini, M Strauss, A Berns |
Nucleic Acids Research | 1997 |
Recombinational construction in Escherichia coli of infectious adenoviral genomes
J Crouzet, L Naudin, C Orsini, E Vigne, L Ferrero, AL Roux, P Benoit, M Latta, C Torrent, D Branellec, P Denèfle, JF Mayaux, M Perricaudet, P Yeh |
Proceedings of the National Academy of Sciences | 1997 |
Transplantation of genetically marked cardiac muscle cells
S Gojo, S Kitamura, O Hatano, A Takakusu, K Hashimoto, Y Kanegae, I Saito |
The Journal of Thoracic and Cardiovascular Surgery | 1997 |
Adenovirus-mediated suicide gene therapy for experimental bladder cancer
MA Sutton, SA Berkman, SH Chen, A Block, TD Dang, MW Kattan, TM Wheeler, DR Rowley, SL Woo, SP Lerner |
Urology | 1997 |
Engineering Tissue-Specific Expression of a Recombinant Adenovirus: Selective Transgene Transcription in the Pancreas Using the Amylase Promoter
RP Dematteo, SJ McClane, K Fisher, H Yeh, G Chu, C Burke, SE Raper |
Journal of Surgical Research | 1997 |
Dissociative expression of adenoviral-mediated E. coli LacZ gene between ischemic and reperfused rat brains
K Abe, Y Setoguchi, T Hayashi, Y Itoyama |
Neuroscience Letters | 1997 |
Adenovirus-mediated myofilament gene transfer into adult cardiac myocytes
MV Westfall, EM Rust, F Albayya, JM Metzger |
Methods in cell biology | 1997 |
Expression from cardiomyocyte-specific promoter after adenovirus-mediated gene transfer in vitro and in vivo
F Griscelli, P Opolon, C Chianale, ND Falco, WM Franz, M Perricaudet, T Ragot |
Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie | 1997 |
Intracoronary gene transfer of immunosuppressive cytokines to cardiac allografts: Method and efficacy of adenovirus-mediated transduction
R Brauner, L Wu, H Laks, M Nonoyama, F Scholl, O Shvarts, A Berk, DC Drinkwater, JL Wang |
The Journal of Thoracic and Cardiovascular Surgery | 1997 |
Efficient Transfer of Genes into Senescent Cells by Adenovirus Vectors via Highly Expressed αvβ5 Integrin
Y Hashimoto, K Kohri, H Akita, K Mitani, K Ikeda, M Nakanishi |
Biochemical and Biophysical Research Communications | 1997 |
Adenoviral Vectors for Hepatic Gene Transfer in Animals
MA Kay |
Chest | 1997 |
Adenovirus-Mediated Transfer of a Dominant-Negative H- ras Suppresses Neointimal Formation in Balloon-Injured Arteries In Vivo
H Ueno, H Yamamoto, S Ito, JJ Li, A Takeshita |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
Gene Transfer in the Cardiovascular System
KL March |
1997 | |
Correction of Hypertriglyceridemia and Impaired Fat Tolerance in Lipoprotein Lipase–Deficient Mice by Adenovirus-Mediated Expression of Human Lipoprotein Lipase
KJ Excoffon, G Liu, L Miao, JE Wilson, BM McManus, CF Semenkovich, T Coleman, P Benoit, N Duverger, D Branellec, P Denefle, MR Hayden, ME Lewis |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
In Utero Cardiac Gene Transfer via Intraplacental Delivery of Recombinant Adenovirus
YJ Woo, GP Raju, JL Swain, ME Richmond, TJ Gardner, RJ Balice-Gordon |
Circulation | 1997 |
Forced expression of the homeodomain protein Gax inhibits cardiomyocyte proliferation and perturbs heart morphogenesis
SA Fisher, E Siwik, D Branellec, K Walsh, M Watanabe |
Development (Cambridge, England) | 1997 |
Efficient introduction of genes into human ovarian surface epithelium
EH Leung, BR Davies, PC Leung, GT Chen, CD Roskelley, N Auersperg |
In vitro cellular & developmental biology. Animal | 1997 |
Gene transfer into mouse embryonic stem cell-derived cardiac myocytes mediated by recombinant adenovirus
EM Rust, MV Westfall, LC Samuelson, JM Metzger |
In vitro cellular & developmental biology. Animal | 1997 |
Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with MyoD
CE Murry, MA Kay, T Bartosek, SD Hauschka, SM Schwartz |
Journal of Clinical Investigation | 1996 |
Adenoviral infection of thyroid cells: A rationale for gene therapy for metastatic thyroid carcinoma
MA Zeiger, Y Takiyama, JO Bishop, AR Ellison, M Saji, MA Levine |
Surgery | 1996 |
Sustained somatic gene inactivation by viral transfer of Cre recombinase
A Rohlmann, M Gotthardt, TE Willnow, RE Hammer, J Herz |
Nature Biotechnology | 1996 |
Gene transfer into the kidney: Promise for unravelling disease mechanisms, limitations for human gene therapy
LG Fine |
Kidney International | 1996 |
Arterial Gene Transfer for Therapeutic Angiogenesis in Patients with Peripheral Artery Disease. St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts
JM Isner, K Walsh, J Symes, A Pieczek, S Takeshita, J Lowry, K Rosenfield, L Weir, E Brogi, D Jurayj |
Human Gene Therapy | 1996 |
Gene Therapy in Lung Transplantation: Feasibility ofEx VivoAdenovirus-Mediated Gene Transfer to the Graft
A Chapelier, C Danel, M Mazmanian, EA Bacha, H Sellak, MA Gilbert, P Hervé, P Lemarchand |
Human Gene Therapy | 1996 |
In VivoExpression of Full-Length Human Dystrophin from Adenoviral Vectors Deleted of All Viral Genes
SE Haecker, HH Stedman, RJ Balice-Gordon, DB Smith, JP Greelish, MA Mitchell, A Wells, HL Sweeney, JM Wilson |
Human Gene Therapy | 1996 |
Dystrophin Expression in Muscles of mdx Mice After Adenovirus-MediatedIn VivoGene Transfer
G Acsadi, H Lochmüller, A Jani, J Huard, B Massie, S Prescott, M Simoneau, BJ Petrof, G Karpati |
Human Gene Therapy | 1996 |
Characterization of 911: A New Helper Cell Line for the Titration and Propagation of Early Region 1-Deleted Adenoviral Vectors
FJ Fallaux, O Kranenburg, SJ Cramer, A Houweling, H Ormondt, RC Hoeben, AJ van der Eb |
Human Gene Therapy | 1996 |
Adenovirus-Mediated Hepatic Gene Transfer in Mice: Comparison of Intravascular and Biliary Administration
MJ Peeters, GA Patijn, A Lieber, L Meuse, MA Kay |
Human Gene Therapy | 1996 |
Cardiovascular Gene Therapy: Current Concepts
JC Fox |
Therapeutic Drug Monitoring | 1996 |
Targeted gene delivery by tropism-modified adenoviral vectors
JT Douglas, BE Rogers, ME Rosenfeld, SI Michael, M Feng, DT Curiel |
Nature Biotechnology | 1996 |
A method to codetect introduced genes and their products in gene therapy protocols
E Gussoni, Y Wang, C Fraefel, RG Miller, HM Blau, AI Geller, LM Kunkel |
Nature Biotechnology | 1996 |
Efficient Transfer of Regulated Genes in Adipocytes and Hepatoma Cells by the Combination of Liposomes and Replication-Deficient Adenovirus
C Meunier-Durmort, N Ferry, B Hainque, J Delattre, C Forest |
European Journal of Biochemistry | 1996 |
Adenoviral-Mediated Herpes Simplex Virus-Thymidine Kinase Gene Transfer in Vivo for Treatment of Experimental Human Melanoma
B Bonnekoh, DA Greenhalgh, DS Bundman, K Kosai, SH Chen, MJ Finegold, T Krieg, SL Woo, DR Roop |
Journal of Investigative Dermatology | 1996 |
Adenovirus-mediated gene transfer into tendon and tendon sheath
J Lou, PR Manske, M Aoki, ME Joyce |
Journal of Orthopaedic Research | 1996 |
Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A
G Warnier, MT Duffour, C Uyttenhove, TF Gajewski, C Lurquin, H Haddada, M Perricaudet, T Boon |
International Journal of Cancer | 1996 |
Immunological approaches in the gene therapy of cancer
T Tursz |
The Breast | 1996 |
Prostate Cancer Gene Therapy: Herpes Simplex Virus Thymidine Kinase Gene Transduction Followed by Ganciclovir in Mouse and Human Prostate Cancer Models
JA Eastham, SH Chen, I Sehgal, G Yang, TL Timme, SJ Hall, SL Woo, TC Thompson |
Human Gene Therapy | 1996 |
Phase Ia Trial of a Polynucleotide Anti-Tumor Immunization to Human Carcinoembryonic Antigen in Patients with Metastatic Colorectal Cancer. University of Alabama at Birmingham, Birmingham, Alabama
RM Conry, AF LoBuglio, DT Curiel |
Human Gene Therapy | 1996 |
Herpes Simplex Virus Thymidine Kinase Gene Therapy for Rat Malignant Brain Tumors
AJ Vincent, R Vogels, GV Someren, MC Esandi, JL Noteboom, CJ Avezaat, C Vecht, DW Bekkum, D Valerio, A Bout, PM Hoogerbrugge |
Human Gene Therapy | 1996 |
In VitroAssessment of Variables Affecting the Efficiency and Efficacy of Adenovirus-Mediated Gene Transfer to Cystic Fibrosis Airway Epithelia
LG Johnson, RJ Pickles, SE Boyles, JC Morris, H Ye, Z Zhou, JC Olsen, RC Boucher |
Human Gene Therapy | 1996 |
In VitroandIn VivoHepatoma Cell-Specific Expression of a Gene Transferred with an Adenoviral Vector
PB Arbuthnot, MP Bralet, CL Jossic, JF Dedieu, M Perricaudet, C Bréchot, N Ferry |
Human Gene Therapy | 1996 |
Non-replicating expression vectors: applications in vaccine development and gene therapy
KJ Limbach, E Paoletti |
Epidemiology and Infection | 1996 |
Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells
S Huang, T Kamata, Y Takada, ZM Ruggeri, GR Nemerow |
Journal of virology | 1996 |
Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein
PD Kessler, GM Podsakoff, X Chen, SA McQuiston, PC Colosi, LA Matelis, GJ Kurtzman, BJ Byrne |
Proceedings of the National Academy of Sciences | 1996 |
Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted
H Zhou, W O'Neal, N Morral, AL Beaudet |
Journal of virology | 1996 |
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism
VN Krasnykh, GV Mikheeva, JT Douglas, DT Curiel |
Journal of virology | 1996 |
Functional protection of dystrophic mouse (mdx) muscles after adenovirus-mediated transfer of a dystrophin minigene
N Deconinck, T Ragot, G Maréchal, M Perricaudet, JM Gillis |
Proceedings of the National Academy of Sciences | 1996 |
Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors
A Amalfitano, CR Begy, JS Chamberlain |
Proceedings of the National Academy of Sciences | 1996 |
Successful expression of human factor IX following repeat administration of adenoviral vector in mice
J Walter, Q You, JN Hagstrom, M Sands, KA High |
Proceedings of the National Academy of Sciences | 1996 |
Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit
P Yeh, JF Dedieu, C Orsini, E Vigne, P Denefle, M Perricaudet |
Journal of virology | 1996 |
Gene-based therapeutic strategies for Human Lipoprotein Lipase (LPL) deficiency: Rationale and prospects for alteration of atherogenic risk
ME Lewis, G Liu, DG Ginzinger, P Benoit, SD Jones, KJ Ashbourne, JE Wilson, BM McManus, N Duverger, PP Denefle, MR Hayden |
Transfusion Science | 1996 |
Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain
MD Bell, DD Taub, SJ Kunkel, RM Strieter, R Foley, J Gauldie, VH Perry |
The European journal of neuroscience | 1996 |
Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
FJ Giordano, P Ping, MD McKirnan, S Nozaki, AN DeMaria, WH Dillmann, O Mathieu-Costello, HK Hammond |
Nature Medicine | 1996 |
GENE THERAPY AND INHERITED DYSLIPIDEMIA
TO MD |
Endocrine Practice | 1996 |
Utilisation des virus comme vecteurs de thérapie génique
M Latta, M Perricaudet, P Yeh |
Revue Française des Laboratoires | 1996 |
Gene transfer by adenovirus in smooth muscle cells
MF Yu, JI Ewaskiewicz, S Adda, K Bailey, V Harris, D Sosnoski, M Tomasic, J Wilson, MI Kotlikoff |
Respiration Physiology | 1996 |
Prospects of gene therapy for genetic skeletal muscle disease
G Karpati, H Lochmuller |
Transfusion Science | 1996 |
Cardiac gene transfer by intracoronary infusion of adenovirus vector—mediated reporter gene in the transplanted mouse heart
J Lee, H Laks, DC Drinkwater, A Blitz, L Lam, Y Shiraishi, P Chang, TA Drake, A Ardehali |
The Journal of Thoracic and Cardiovascular Surgery | 1996 |
Retroviral vectors to study cardiovascular development
T Mikawa, J Hyer, N Itoh, Y Wei |
Trends in Cardiovascular Medicine | 1996 |
ADENOVIRUS-MEDIATED GENE TRANSFER INTO RAT CARDIAC ALLOGRAFTS: Comparison of Direct Injection and Perfusion1
J Wang, Y NA, SJ Knechtle |
Transplantation | 1996 |
Potential Gene Therapy for Lecithin-Cholesterol Acyltransferase (LCAT)–Deficient and Hypoalphalipoproteinemic Patients With Adenovirus-Mediated Transfer of Human LCAT Gene
S Seguret-Mace, M Latta-Mahieu, G Castro, G Luc, JC Fruchart, E Rubin, P Denefle, N Duverger |
Circulation | 1996 |
Avoidance of Immune Response Prolongs Expression of Genes Delivered to the Adult Rat Myocardium by Replication-Defective Adenovirus
MJ Quinones, J Leor, RA Kloner, M Ito, M Patterson, WF Witke, L Kedes |
Circulation | 1996 |
Chirurgisches Forum ’96 fur experimentelle und klinische Forschung
HG Beger, D Birk, L Staib, R Pichlmayr, J Seifert, W Hartel |
1996 | |
Triggering of Acute Coronary Syndromes
SN Willich, JE Muller |
1996 | |
Yearbook of Cell and Tissue Transplantation 1996–1997
RP Lanza, WL Chick |
1996 | |
59. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie e.V
G Muhr, KE Rehm |
1996 | |
Targeting of Drugs 5
G Gregoriadis, B McCormack |
1996 | |
Genetic Approaches to Noncommunicable Diseases
K Berg, V Boulyjenkov, Y Christen |
1996 | |
Gene Therapy for Plastic and Reconstructive Surgery
SM Shenaq, ED Rabinovsky |
Clinics in Plastic Surgery | 1996 |
Strategies for cancer gene therapy using adenoviral vectors
V Descamps, , , N Fernandez, L Cordier, MA Abina, E Kremer, M Perricaudet, H Haddada |
Journal of Molecular Medicine | 1996 |
Non-replicating expression vectors: applications in vaccine development and gene therapy.
Limbach KJ, Paoletti E |
Epidemiology and Infection | 1996 |
Targeted expression of transforming growth factor-beta 1 in intracardiac grafts promotes vascular endothelial cell DNA synthesis
GY Koh, SJ Kim, MG Klug, K Park, MH Soonpaa, LJ Field |
Journal of Clinical Investigation | 1995 |
Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo
PB McCray, K Armstrong, J Zabner, DW Miller, GA Koretzky, L Couture, JE Robillard, AE Smith, MJ Welsh |
Journal of Clinical Investigation | 1995 |
Low-efficiency of percutaneous adenovirus-mediated arterial gene transfer in the atherosclerotic rabbit
LJ Feldman, PG Steg, LP Zheng, D Chen, M Kearney, SE McGarr, JJ Barry, JF Dedieu, M Perricaudet, JM Isner |
Journal of Clinical Investigation | 1995 |
Adenovirus-mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocytes) and in vivo (rat liver). A novel strategy for modifying excitability
DC Johns, HB Nuss, N Chiamvimonvat, BM Ramza, E Marban, JH Lawrence |
Journal of Clinical Investigation | 1995 |
Regenerating Cells in Human Airway Surface Epithelium Represent Preferential Targets for Recombinant Adenovirus
F Dupuit, JM Zahm, D Pierrot, S Brezillon, N Bonnet, JL Imler, A Pavirani, E Puchelle |
Human Gene Therapy | 1995 |
Adenovirus-Mediated Gene Transfer to the Respiratory Tract of Fetal SheepIn Utero
MC Vincent, BC Trapnell, RP Baughman, SE Wert, JA Whitsett, HS Iwamoto |
Human Gene Therapy | 1995 |
Prevention of restenosis after coronary angioplasty: towards a molecular approach?
LJ Feldman, R Riessen, PG Steg |
Fundamental & Clinical Pharmacology | 1995 |
Adenovirus-Mediated Gene Transfer to the Respiratory Tract of Fetal Sheep In Utero
MC Vincent, BC Trapnell, RP Baughman, SE Wert, JA Whitsett, HS Iwamoto |
Human Gene Therapy | 1995 |
Tetracycline-regulated gene expression following direct gene transfer into mouse skeletal muscle
J Dhawan, TA Rando, SL Elson, H Bujard, HM Blau |
Somatic Cell and Molecular Genetics | 1995 |
Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses
O Sabaté, P Horellou, E Vigne, P Colin, M Perricaudet, MH Buc-Caron, J Mallet |
Nature Genetics | 1995 |
Myoblast transfer and gene therapy in muscular dystrophies
CN Pagel, JE Morgan |
Microscopy Research and Technique | 1995 |
Inhibition of Melanoma Growth by Adenoviral-Mediated HSV Thymidine Kinase Gene Transfer In Vivo
B Bonnekoh, DA Greenhalgh, DS Bundman, JN Eckhardt, MA Longley, SH Chen, SL Woo, DR Roop |
Journal of Investigative Dermatology | 1995 |
Toward a gene therapy for duchenne muscular dystrophy
MG Dunckley, TA Piper, G Dickson |
Mental Retardation and Developmental Disabilities Research Reviews | 1995 |
Prospects for Gene Therapy with Direct Injection of Polynucleotides
A Kass-Eisler, K Li, LA Leinwand |
Annals of the New York Academy of Sciences | 1995 |
Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
V Juillard, P Villefroy, D Godfrin, A Pavirani, A Venet, JG Guillet |
European Journal of Immunology | 1995 |
Prenatal gene therapy: Prospects and issues
E Pergament, M Fiddler |
Prenatal Diagnosis | 1995 |
Strategies for Myocardial Repair
GY Koh, MH Soonpaa, MG Klug, LJ Field |
Journal of Interventional Cardiology | 1995 |
Potential gene therapy strategies in the treatment of cardiovascular disease
RT Rowland, JC Cleveland, X Meng, AH Harken, JM Brown |
The Annals of Thoracic Surgery | 1995 |
Transient Expression of Genes TransferredIn Vivointo Heart Using First-Generation Adenoviral Vectors: Role of the Immune Response
H Gilgenkrantz, D Duboc, V Juillard, D Couton, A Pavirani, JG Guillet, P Briand, A Kahn |
Human Gene Therapy | 1995 |
Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery
PR Clemens, TL Krause, S Chan, KE Korb, FL Graham, CT Caskey |
Human Gene Therapy | 1995 |
Adenovirus-Mediated Transfer of the Amphotropic Retrovirus Receptor cDNA Increases Retroviral Transduction in Cultured Cells
A Lieber, MJ Peeters, MA Kay |
Human Gene Therapy | 1995 |
In utero gene transfer into the pulmonary epithelium
HS Sekhon, JE Larson |
Nature Medicine | 1995 |
Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer
T Li, BL Davidson |
Proceedings of the National Academy of Sciences | 1995 |
Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery
MW Chang, T Ohno, D Gordon, MM Lu, GJ Nabel, EG Nabel, JM Leiden |
Molecular Medicine | 1995 |
Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression
M Anton, FL Graham |
Journal of virology | 1995 |
Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo
A Lieber, MJ Peeters, L Meuse, N Fausto, J Perkins, MA Kay |
Proceedings of the National Academy of Sciences | 1995 |
Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
S Huang, RI Endo, GR Nemerow |
Journal of virology | 1995 |
The Gordon Wilson Lecture. In vivo gene therapy: a strategy to use human genes as therapeutics
RG Crystal |
Transactions of the American Clinical and Climatological Association | 1995 |
Adenovirus-rnediated expression of a reporter gene in thalamocortical cocultures
MF Wilkemeyer, KJ Angelides |
Brain Research | 1995 |
Genetic Manipulation of the Nervous System
M Heilig, KH Schlingensiepen |
Genetic Manipulation of the Nervous System | 1995 |
Liver-directed gene therapy: molecular tools and current preclinical and clinical studies
M Alt, WH Caselmann |
Journal of Hepatology | 1995 |
Molecular and Cell Biology of Human Gene Therapeutics
G Dickson |
1995 | |
Quantitative Analysis of Repeat Adenovirus-Mediated Gene Transfer Into Injured Canine Femoral Arteries
H Ueno, JJ Li, H Tomita, H Yamamoto, Y Pan, Y Kanegae, I Saito, A Takeshita |
Arteriosclerosis, thrombosis, and vascular biology | 1995 |
Cardiovascular Disease 2
LL Gallo |
1995 | |
Molecular and Subcellular Cardiology
S Sideman, R Beyar |
1995 | |
Viruses in Human Gene Therapy
JM Vos |
1995 | |
The Molecular Repertoire of Adenoviruses III
W Doerfler, P Böhm |
1995 | |
Current aspects of gene therapy: implications for vascular interventions
F Reifers, J Kreuzer |
Journal of Molecular Medicine | 1995 |
Adenovirus-mediated gene transfer into striated muscles
G Acsadi, A Jani, B Massie |
Journal of Molecular Medicine | 1995 |
Tetracycline-regulated cardiac gene expression in vivo
GI Fishman, ML Kaplan, PM Buttrick |
Journal of Clinical Investigation | 1994 |
Prospects for site-specific delivery of pharmacologic and molecular therapies
R Riessen, JM Isner |
Journal of the American College of Cardiology | 1994 |
Increasing Expression of the Normal Human CFTR cDNA in Cystic Fibrosis Epithelial Cells Results in a Progressive Increase in the Level of CFTR Protein Expression, but a Limit on the Level of cAMP-Stimulated Chloride Secretion
MA Rosenfeld, SJ Rosenfeld, C Danel, TC Banks, RG Crystal |
Human Gene Therapy | 1994 |
Gene Transfer to Human Fetal Pulmonary Tissue Developed in Immunodeficient SCID Mice
B Péault, R Tirouvanziam, MN Sombardier, S Chen, M Perricaudet, D Gaillard |
Human Gene Therapy | 1994 |
Acute Responses of Non-Human Primates to Airway Delivery of an Adenovirus Vector Containing the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA
SL Brody, M Metzger, C Danel, MA Rosenfeld, RG Crystal |
Human Gene Therapy | 1994 |
Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen
HL Davis, ML Michel, M Mancini, M Schleef, RG Whalen |
Vaccine | 1994 |
Cell and Gene Therapy in Duchenne Muscular Dystrophy
JE Morgan |
Human Gene Therapy | 1994 |
Erythropoietin Gene Transfer and Expression in Adult Normal Mice: Use of an Adenovirus Vector
V Descamps, N Blumenfeld, JL Villeval, W Vainchenker, M Perricaudet, Y Beuzard |
Human Gene Therapy | 1994 |
DirectIn VivoGene Transfer and Expression in Malignant Cells Using Adenovirus Vectors
SL Brody, HA Jaffe, SK Han, RP Wersto, RG Crystal |
Human Gene Therapy | 1994 |
Ex Vivo and In Vivo Gene Transfer to The Skin Using Replication-Deficient Recombinant Adenovirus Vectors
Y Setoguchi, HA Jaffe, C Danel, RG Crystal |
Journal of Investigative Dermatology | 1994 |
Adenoviral-mediated gene transfer to renal tubular cells in vivo
P Moullier, G Friedlander, D Calise, P Ronco, M Perricaudet, N Ferry |
Kidney International | 1994 |
Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
RC Boucher, MR Knowles, LG Johnson, JC Olsen, R Pickles, JM Wilson, J Engelhardt, Y Yang, M Grossman |
Human Gene Therapy | 1994 |
Gene therapy using adenoviral vectors
BC Trapnell, M Gorziglia |
Current Opinion in Biotechnology | 1994 |
Transduction of Human Bone Marrow by Adenoviral Vector
K Mitani, FL Graham, CT Caskey |
Human Gene Therapy | 1994 |
Lung Gene Therapy:In VivoAdenovirus-Mediated Gene Transfer to Rhesus Monkey Airway Epithelium
A Bout, M Perricaudet, G Baskin, JL Imler, BJ Scholte, A Pavirani, D Valerio |
Human Gene Therapy | 1994 |
Adenovirus-mediated delivery into myocytes of muscle glycogen phosphorylase, the enzyme deficient in patients with glycogen-storage disease type V
S Baqué, CB Newgard, RD Gerard, JJ Guinovart, AM Gómez-Foix |
Biochemical Journal | 1994 |
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer
J Kolls, K Peppel, M Silva, B Beutler |
Proceedings of the National Academy of Sciences | 1994 |
Coronary restenosis and gene therapy
W Mazur, NM Ali, AE Raizner, BA French |
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital | 1994 |
Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
SH Chen, HD Shine, JC Goodman, RG Grossman, SL Woo |
Proceedings of the National Academy of Sciences | 1994 |
In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs
MA Kay, CN Landen, SR Rothenberg, LA Taylor, F Leland, S Wiehle, B Fang, D Bellinger, M Finegold, AR Thompson |
Proceedings of the National Academy of Sciences | 1994 |
In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus
JL Bessereau, LD Stratford-Perricaudet, J Piette, CL Poupon, JP Changeux |
Proceedings of the National Academy of Sciences | 1994 |
Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus
SK Tripathy, E Goldwasser, MM Lu, E Barr, JM Leiden |
Proceedings of the National Academy of Sciences | 1994 |
Adenoviral vectors as functional retrograde neuronal tracers
V Ridoux, JJ Robert, X Zhang, M Perricaudet, J Mallet, GL la Salle |
Brain Research | 1994 |
Advances in Pharmacology
B Drenger, Y Ginosar, Y Gozal |
Advances in Pharmacology | 1994 |
Gene therapy—Its potential in the management of oral cancer
EJ Shillitoe, JN Lapeyre, K Adler-Storthz |
European Journal of Cancer. Part B: Oral Oncology | 1994 |
Use of recombinant adenovirus for metabolic engineering of mammalian cells
EV Schaftingen, B Lederer, R Bartrons, HG Hers |
Methods in cell biology | 1994 |
Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors
BA French, W Mazur, RS Geske, R Bolli |
Circulation | 1994 |
The new frontier: gene and oligonucleotide therapy
H Schreier |
Pharmaceutica Acta Helvetiae | 1994 |
Expression of a recombinant dystrophin in mdx mice using adenovirus vector
HS Alameddine, B Quantin, A Cartaud, M Dehaupas, JL Mandel, M Fardeau |
Neuromuscular Disorders | 1994 |
Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder
H Maeda, C Danel, RG Crystal |
Gastroenterology | 1994 |
Somatic gene therapy for cardiovascular disease
E Barr, JM Leiden |
Trends in Cardiovascular Medicine | 1994 |
Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis
BA French, W Mazur, NM Ali, RS Geske, JP Finnigan, GP Rodgers, R Roberts, AE Raizner |
Circulation | 1994 |
Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterol
WP Kopfler, M Willard, T Betz, JE Willard, RD Gerard, RS Meidell |
Circulation | 1994 |
Catheter-mediated pulmonary vascular gene transfer and expression
DW Muller, D Gordon, H San, Z Yang, VJ Pompili, GJ Nabel, EG Nabel |
Circulation research | 1994 |
Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector
PG Steg, LJ Feldman, JY Scoazec, O Tahlil, JJ Barry, S Boulechfar, T Ragot, JM Isner, M Perricaudet |
Circulation | 1994 |
Gene Therapeutics
JA Wolff |
1994 | |
Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity
V Felipo, S Grisolia |
1994 | |
In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
KF Kozarsky, DR McKinley, LL Austin, SE Raper, LD Stratford-Perricaudet, JM Wilson |
The Journal of biological chemistry | 1994 |
Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer
A Mastrangeli, C Danel, MA Rosenfeld, L Stratford-Perricaudet, M Perricaudet, A Pavirani, JP Lecocq, RG Crystal |
Journal of Clinical Investigation | 1993 |
Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes
MA Morsy, EL Alford, A Bett, FL Graham, CT Caskey |
Journal of Clinical Investigation | 1993 |
Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses
JF Engelhardt, Y Yang, LD Stratford-Perricaudet, ED Allen, K Kozarsky, M Perricaudet, JR Yankaskas, JM Wilson |
Nature Genetics | 1993 |
Gene therapy for duchenne dystrophy
AG Engel |
Annals of Neurology | 1993 |
Arterial Gene Transfer Using Pure DNA Applied Directly to a Hydrogel-Coated Angioplasty Balloon
R Riessen, H Rahimizadeh, E Blessing, S Takeshita, JJ Barry, JM Isner |
Human Gene Therapy | 1993 |
Adenoviral Interleukin-2 Gene Transfer into P815 Tumor Cells Abrogates Tumorigenicity and Induces Antitumoral Immunity in Mice
H Haddada, T Ragot, L Cordier, MT Duffour, M Perricaudet |
Human Gene Therapy | 1993 |
Adenoviral Vector as a Gene Delivery System into Cultured Rat Neuronal and Glial Cells
C Caillaud, S Akli, E Vigne, A Koulakoff, M Perricaudet, L Poenaru, A Kahn, Y Berwald-Netter |
European Journal of Neuroscience | 1993 |
Long–term correction of mouse dystrophic degeneration by adenovirus–mediated transfer of a minidystrophin gene
N Vincent, T Ragot, H Gilgenkrantz, D Couton, P Chafey, A Grégoire, P Briand, JC Kaplan, A Kahn, M Perricaudet |
Nature Genetics | 1993 |
Transfer of a foreign gene into the brain using adenovirus vectors
S Akli, C Caillaud, E Vigne, LD Stratford-Perricaudet, L Poenaru, M Perricaudet, A Kahn, MR Peschanski |
Nature Genetics | 1993 |
Delivering therapeutic genes — matching approach and application
K Mitani, CT Caskey |
Trends in Biotechnology | 1993 |
Assessment of Recombinant Adenoviral Vectors for Hepatic Gene Therapy
Q Li, MA Kay, M Finegold, LD Stratford-Perricaudet, SL Woo |
Human Gene Therapy | 1993 |
Direct Gene Transfer into Skeletal MuscleIn Vivo: Factors Affecting Efficiency of Transfer and Stability of Expression
HL Davis, RG Whalen, BA Demeneix |
Human Gene Therapy | 1993 |
Plasmid DNA Is Superior to Viral Vectors for Direct Gene Transfer into Adult Mouse Skeletal Muscle
HL Davis, BA Demeneix, B Quantin, J Coulombe, RG Whalen |
Human Gene Therapy | 1993 |
Human genetic therapy
J Harris, K Sikora |
Molecular Aspects of Medicine | 1993 |
Gene therapy: adenovirus vectors
KF Kozarsky, JM Wilson |
Current Opinion in Genetics & Development | 1993 |
Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice
TA Smith, MG Mehaffey, DB Kayda, JM Saunders, S Yei, BC Trapnell, A McClelland, M Kaleko |
Nature Genetics | 1993 |
Packaging capacity and stability of human adenovirus type 5 vectors
AJ Bett, L Prevec, FL Graham |
Journal of virology | 1993 |
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo
A Kass-Eisler, E Falck-Pedersen, M Alvira, J Rivera, PM Buttrick, BA Wittenberg, L Cipriani, LA Leinwand |
Proceedings of the National Academy of Sciences | 1993 |
Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants
M Cotten, E Wagner, K Zatloukal, ML Birnstiel |
Journal of virology | 1993 |
Direct gene transfer into mouse diaphragm
HL Davis, BJ Jasmin |
FEBS Letters | 1993 |
An adenovirus vector for gene transfer into neurons and glia in the brain
GL la Salle, J Robert, S Berrard, V Ridoux, L Stratford-Perricaudet, M Perricaudet, J Mallet |
Science | 1993 |
The basic science of gene therapy
RC Mulligan |
Science | 1993 |
Overview: In Vivo Expression of Human Genes
AE Canonico, KL Brigham |
Current Opinion on Therapeutic Patents | 1993 |
Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice
T Ragot, N Vincent, P Chafey, E Vigne, H Gilgenkrantz, D Coutont, J Cartaud, P Briand, JC Kaplant, M Perricaude, A Kahn |
Nature | 1993 |
Regulation of myosin heavy chain genes in the heart
E Morkin |
Circulation | 1993 |
Efficient and selective adenovirus-mediated gene transfer into vascular neointima
RJ Guzman, P Lemarchand, RG Crystal, SE Epstein, T Finkel |
Circulation | 1993 |
Efficient gene transfer into myocardium by direct injection of adenovirus vectors
RJ Guzman, P Lemarchand, RG Crystal, SE Epstein, T Finkel |
Circulation research | 1993 |
In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries
SW Lee, BC Trapnell, JJ Rade, R Virmani, DA Dichek |
Circulation research | 1993 |
In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors
P Lemarchand, M Jones, I Yamada, RG Crystal |
Circulation research | 1993 |
The advent of adenovirus. Gene therapy for cardiovascular disease
MD Schneider, BA French |
Circulation | 1993 |
Adenovirus–mediated in vivo gene transfer and expression in normal rat liver
HA Jaffe, C Danel, G Longenecker, M Metzger, Y Setoguchi, MA Rosenfeld, TW Gant, SS Thorgeirsson, LD Stratford-Perricaudet, M Perricaudet, A Pavirani, JP Lecocq, RG Crystal |
Nature Genetics | 1992 |
Advances in Genetics
BH Bowman, F Yang, GS Adrian |
Advances in genetics | 1988 |