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Citations to this article

Widespread long-term gene transfer to mouse skeletal muscles and heart.
L D Stratford-Perricaudet, … , M Perricaudet, P Briand
L D Stratford-Perricaudet, … , M Perricaudet, P Briand
Published August 1, 1992
Citation Information: J Clin Invest. 1992;90(2):626-630. https://doi.org/10.1172/JCI115902.
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Widespread long-term gene transfer to mouse skeletal muscles and heart.

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Abstract

Successful treatment of muscular disorders awaits an adapted gene delivery protocol. The clinically applicable technique used for hematopoietic cells which is centered around implantation of retrovirally modified cells may not prove sufficient for a reversal of phenotype when muscle diseases are concerned. We report here efficient, long-term in vivo gene transfer throughout mouse skeletal and cardiac muscles after intravenous administration of a recombinant adenovirus. This simple, direct procedure raises the possibility that muscular degenerative diseases might one day be treatable by gene therapy.

Authors

L D Stratford-Perricaudet, I Makeh, M Perricaudet, P Briand

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Binding Properties, Cell Delivery, and Gene Transfer of Adenoviral Penton Base Displaying Bacteriophage
MD Giovine, B Salone, Y Martina, V Amati, G Zambruno, E Cundari, CM Failla, I Saggio
Virology 2001
Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: a rodent model of IL-4-induced hepatitis
C Guillot, H Coathalem, J Chetritt, A David, P Lowenstein, E Gilbert, L Tesson, N Rooijen, MC Cuturi, JP Soulillou, I Anegon
Journal of immunology (Baltimore, Md. : 1950) 2001
Adult cardiac myocytes survive and remain excitable during long-term culture on synthetic supports
TA Folliguet, C Rücker-Martin, C Pavoine, E Deroubaix, M Henaff, JJ Mercadier, SN Hatem
The Journal of Thoracic and Cardiovascular Surgery 2001
Tumor-specific gene expression in hepatic metastases by a replication-activated adenovirus vector
DS Steinwaerder, CA Carlson, DL Otto, ZY Li, S Ni, A Lieber
Nature Medicine 2001
PROLONGATION OF ALLOGRAFT SURVIVAL WITH VIRAL IL-10 TRANSFECTION IN A HIGHLY HISTOINCOMPATIBLE MODEL OF RAT HEART ALLOGRAFT REJECTION1:
X Zuo, C Wang, D Carpenter, Y Okada, E Nicolaidou, M Toyoda, A Trento, SC Jordan
Transplantation 2001
Surgery
JA Norton, RR Bollinger, AE Chang, SF Lowry, SJ Mulvihill, HI Pass, RW Thompson
Surgery 2001
Effects of adenoviral wild-type p53 gene transfer in p53 -mutated lymphoma cells
P Buttgereit, F Schakowski, A Märten, K Brand, S Renoth, C Ziske, B Schöttker, O Ebert, R Schroers, IG Schmidt-Wolf
Cancer Gene Therapy 2001
Animal Cell Technology: From Target to Market
E Lindner-Olsson, N Chatzissavidou, E Lüllau
2001
Chromosomal Integration Pattern of a Helper-Dependent Minimal Adenovirus Vector with a Selectable Marker Inserted into a 27.4-Kilobase Genomic Stuffer
M Hillgenberg, H Tönnies, M Strauss
Journal of virology 2001
Adenovirus vector-directed expression of the neurotrophin-3 receptor (TrkC) in mouse astrocytes
JA Rubio
Journal of Neurovirology 2001
Partial Correction of the Urinary Concentrating Defect in Aquaporin-1 Null Mice by Adenovirus-Mediated Gene Delivery
Baoxue Yang, Tonghui, J.-Y. Dong, A.S. Verkman
Human Gene Therapy 2000
Gene therapy for vein grafts
MJ Mann
Current Cardiology Reports 2000
Recent developments in gene therapy for cardiac disease
S Wattanapitayakul
Biomedecine & Pharmacotherapy 2000
Cystic Fibrosis Transmembrane Conductance Regulator Does Not Affect Neutrophil Migration across Cystic Fibrosis Airway Epithelial Monolayers
L Pizurki, MA Morris, M Chanson, M Solomon, A Pavirani, I Bouchardy, S Suter
The American Journal of Pathology 2000
Heterotopic Ossification of Degenerating Rat Skeletal Muscle Induced by Adenovirus-Mediated Transfer of Bone Morphogenetic Protein-2 Gene
K Gonda, T Nakaoka, K Yoshimura, Y Otawara-Hamamoto, K Harrii
Journal of Bone and Mineral Research 2000
Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization
K Spilsbury, KL Garrett, WY Shen, IJ Constable, PE Rakoczy
The American Journal of Pathology 2000
The role of IL-6 in the inflammatory and humoral response to adenoviral vectors
K Benihoud, B Salone, S Esselin, P Opolon, V Poli, MD Giovine, M Perricaudet, I Saggio
The Journal of Gene Medicine 2000
Heat Shock Protein 70 Is Required for the Survival of Cancer Cells
J Nylandsted, K Brand, M Jäättelä
Annals of the New York Academy of Sciences 2000
Overexpression of Glutathione Peroxidase Increases the Resistance of Neuronal Cells to Aβ-Mediated Neurotoxicity
M Barkats, S Millecamps, P Abrioux, MC Geoffroy, J Mallet
Journal of Neurochemistry 2000
Gene transfer to urethral strictures in rabbits: a preliminary report
P Meria, M Anidjar, JP Brouland, P Teillac, P Berthon, O Cussenot
BJU International 2000
Optimization of Adenoviral Vector-Mediated Gene Transfer to Pulmonary Arteries in Newborn Swine
S Badran, SK Schachtner, HS Baldwin, JJ Rome
Human Gene Therapy 2000
Comparative in Vivo Approaches for Selective Adenovirus-Mediated Gene Delivery to the Placenta
A Xing, P Boileau, M Cauzac, JC Challier, J Girard, SH Mouzon
Human Gene Therapy 2000
Modulation of Starling Forces and Muscle Fiber Maturity Permits Adenovirus-Mediated Gene Transfer to Adult Dystrophic (mdx) Mice by the Intravascular Route
WK Cho, S Ebihara, J Nalbantoglu, R Gilbert, B Massie, P Holland, G Karpati, BJ Petrof
Human Gene Therapy 2000
A bcl-xS adenovirus selectively induces apoptosis in transformed cells compared to normal mammary cells
VN Sumantran, DS Lee, KM Ignatoski, SP Ethier, MS Wicha
Neoplasia (New York, N.Y.) 2000
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
J Nylandsted, M Rohde, K Brand, L Bastholm, F Elling, M Jäättelä
Proceedings of the National Academy of Sciences 2000
Noninvasive measurement of gene expression in skeletal muscle
G Walter, ER Barton, HL Sweeney
Proceedings of the National Academy of Sciences 2000
Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer
A Ghodsi, C Stein, T Derksen, I Martins, RD Anderson, BL Davidson
Experimental Neurology 2000
Systemic Administration of HVJ Viral Coat–Liposome Complex Containing Human Insulin Vector Decreases Glucose Level in Diabetic Mouse: A Model of Gene Therapy
R Morishita, GH Gibbons, Y Kaneda, T Ogihara, VJ Dzau
Biochemical and Biophysical Research Communications 2000
Expression of Palmitoyl Protein Thioesterase in Neurons
O Heinonen, A Kyttälä, E Lehmus, T Paunio, L Peltonen, A Jalanko
Molecular Genetics and Metabolism 2000
Structural and Functional Characterizations of the 5′-Flanking Region of the Mouse Glucagon Receptor Gene: Comparison with the Rat Gene
A Geiger, JF Decaux, R Burcelin, AL Cam, G Salazar, MJ Charron, J Girard, A Kervran
Biochemical and Biophysical Research Communications 2000
Prospects for gene therapy for inherited cardiomyopathies
NE Bowles, K Bowles, JA Towbin
Progress in Pediatric Cardiology 2000
The Role of Vascular Endothelial Growth Factor (VEGF) in Abnormal Vascular Changes in the Adult Rat Eye
MJ Yu, WY Shen, MC Lai, IJ Constable, JM Papadimitriou, PE Rakoczy
Growth Factors 2000
DNA/Dendrimer Complexes Mediate Gene Transfer into Murine Cardiac Transplants ex Vivo
Y Wang, P Boros, J Liu, L Qin, Y Bai, AU Bielinska, JF Kukowska-Latallo, JR Baker, JS Bromberg
Molecular Therapy 2000
Effect of percutaneous adenovirus-mediated Gax gene delivery to the arterial wall in double-injured atheromatous stented rabbit iliac arteries
L Maillard, EV Belle, FO Tio, A Rivard, M Kearney, D Branellec, PG Steg, JM Isner, K Walsh
Gene Therapy 2000
Direct intra-cardiomuscular transfer of β2-adrenergic receptor gene augments cardiac output in cardiomyopathic hamsters
K Tomiyasu, Y Oda, M Nomura, E Satoh, S Fushiki, J Imanishi, M Kondo, O Mazda
Gene Therapy 2000
Gene transfer of recombinant endothelial nitric oxide synthase to liver in vivo and in vitro
V Shah, AF Chen, S Cao, H Hendrickson, D Weiler, L Smith, J Yao, ZS Katusic
AJP Gastrointestinal and Liver Physiology 2000
Activation of heat-shock response by an adenovirus is essential for virus replication
JB Glotzer, M Saltik, S Chiocca, AI Michou, P Moseley, M Cotten
Nature 2000
Suppression of pulmonary metastasis using adenovirally motility related protein-1 (MRP-1/CD9) gene delivery
M Miyake, H Inufusa, M Adachi, H Ishida, H Hashida, T Tokuhara, Y Kakehi
Oncogene 2000
Analysis of Muscle Creatine Kinase Regulatory Elements in Recombinant Adenoviral Vectors
MA Hauser, A Robinson, D Hartigan-O'Connor, DA Williams-Gregory, JN Buskin, S Apone, CJ Kirk, S Hardy, SD Hauschka, JS Chamberlain
Molecular Therapy 2000
Stable Transduction of Actively Dividing Cells via a Novel Adenoviral/Episomal Vector
H Leblois, C Roche, ND Falco, C Orsini, P Yeh, M Perricaudet
Molecular Therapy 2000
Immunolocalization and Adenoviral Vector-mediated Manganese Superoxide Dismutase Gene Transfer to Experimental Oral Tumors
EW Lam, HM Hammad, R Zwacka, CJ Darby, KR Baumgardner, BL Davidson, TD Oberley, JF Engelhardt, LW Oberley
Journal of dental research 2000
In Vivo Adenovirus-Mediated Suicide Gene Therapy of Orthotopic Bladder Cancer
MA Sutton, CT Freund, SA Berkman, TD Dang, MW Kattan, TM Wheeler, DR Rowley, SP Lemer
Molecular Therapy 2000
In Vivo Transduction of Cerebellar Purkinje Cells Using Adeno-Associated Virus Vectors
WF Kaemmerer, RG Reddy, CA Warlick, SD Hartung, RS McIvor, WC Low
Molecular Therapy 2000
High-Efficiency, Long-Term Cardiac Expression of Foreign Genes in Living Mouse Embryos and Neonates
G Christensen, S Minamisawa, PJ Gruber, Y Wang, KR Chien
Circulation 2000
Clinical Trials in Coronary Angiogenesis: Issues, Problems, Consensus: An Expert Panel Summary
M Simons, RO Bonow, NA Chronos, DJ Cohen, FJ Giordano, HK Hammond, RJ Laham, W Li, M Pike, FW Sellke, TJ Stegmann, JE Udelson, TK Rosengart
Circulation 2000
Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuronopathy
T Bordet, H Schmalbruch, B Pettmann, A Hagege, L Castelnau-Ptakhine, A Kahn, G Haase
Journal of Clinical Investigation 1999
Regulation of smooth muscle cell migration and integrin expression by the Gax transcription factor
B Witzenbichler, Y Kureishi, Z Luo, AL Roux, D Branellec, K Walsh
Journal of Clinical Investigation 1999
Systemic Delivery of Antiangiogenic Adenovirus AdmATF Induces Liver Resistance to Metastasis and Prolongs Survival of Mice
H Li, F Griscelli, F Lindenmeyer, P Opolon, LQ Sun, E Connault, J Soria, C Soria, M Perricaudet, P Yeh
Human Gene Therapy 1999
URETERAL GENE TRANSFER TO PORCINE INDUCED STRICTURES USING ENDOUROLOGIC DELIVERY OF AN ADENOVIRAL VECTOR
M Anidjar, P Mongiat-Artus, JP Brouland, B Cochand-Priollet, P Teillac, AL Duc, P Berthon, O Cussenot
The Journal of Urology 1999
Molecular targets of gene therapy
DK Das, RM Engelman, N Maulik, JA Rousou, JE Flack, DW Deaton
The Annals of Thoracic Surgery 1999
Adenovirus-mediated gene transfer to the peritoneum and hepatic parenchyma of fetal mice in utero
GS Lipshutz, L Flebbe-Rehwaldt, KM Gaensler
Surgery 1999
Gene therapy for Parkinson’s disease: review and update
UJ Kang, DM Frim
Expert Opinion on Investigational Drugs 1999
Brain-Derived Neurotrophic Factor-Mediated Protection of Striatal Neurons in an Excitotoxic Rat Model of Huntington's Disease, as Demonstrated by Adenoviral Gene Transfer
AP Bemelmans, P Horellou, L Pradier, I Brunet, P Colin, J Mallet
Human Gene Therapy 1999
Solvoplex: A New Type of Synthetic Vector for Intrapulmonary Gene Delivery
K Schughart, R Bischoff, UB Rasmussen, DA Hadji, F Perraud, N Accart, O Boussif, N Silvestre, Y Cordier, A Pavirani, HV Kolbe
Human Gene Therapy 1999
A commentary on glial cell line-derived neurotrophic factor (GDNF) From a glial secreted molecule to gene therapy
M Bohn
Biochemical Pharmacology 1999
Adenovirus-mediated introduction of DNA into pig sperm and offspring
L Farre, T Rigau, T Mogas, M Garc�a-Rocha, M Canal, AM Gomez-Foix, JE Rodr�guez-Gil
Molecular Reproduction and Development 1999
Gene Transfer And Models Of Gene Therapy For The Myocardium
MY Alexander, KA Webster, PH McDonald, HM Prentice
Clinical and Experimental Pharmacology and Physiology 1999
Therapeutic benefit of ciliary neurotrophic factor in progressive motor neuronopathy depends on the route of delivery
G Haase, B Pettmann, T Bordet, P Villa, E Vigne, H Schmalbruch, A Kahn
Annals of Neurology 1999
Angiogenic growth factor release system for in vivo tissue engineering: a trial of bone marrow transplantation into ischemic myocardium
Y Noishiki, Y Ichikawa, I Yamazaki, M Mo, K Yamamoto, T Kosuge, K Takahashi, Y Yamane
Journal of Artificial Organs 1999
Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B
H Schneider, S Adebakin, M Themis, T Cook, AM Douar, A Pavirani, C Coutelle
The Journal of Gene Medicine 1999
Adenovirus-mediated suicide gene therapy in an in vitro model of reactive gliosis
S Audouy, J Mallet, A Privat, MG Ribotta
Glia 1999
A MAGE-A4 peptide presented by HLA-A2 is recognized by cytolytic T lymphocytes
MT Duffour, P Chaux, C Lurquin, G Cornelis, T Boon, PV der Bruggen
European Journal of Immunology 1999
Adenovirus vectors for gene delivery
K Benihoud
Current Opinion in Biotechnology 1999
Effective gene transfer oflacZ andP0 into Schwann cells of P0-deficient mice
V Gu�nard, B Schweitzer, E Flechsig, S Hemmi, R Martini, U Suter, M Schachner
Glia 1999
Cationic Lipids and Polymers Are Able to Enhance Adenoviral Infection of Cultured Mouse Myotubes
E Dodds, TA Piper, SJ Murphy, G Dickson
Journal of Neurochemistry 1999
Human Tissue Kallikrein Attenuates Hypertension and Secretes into Circulation and Urine After Intramuscular Gene Delivery in Hypertensive Rats
JJ Zhang, C Wang, KF Lin, L Chao, J Chao
Clinical and Experimental Hypertension 1999
Novel Human Gene Transfer Vectors: Evaluation of Wild-Type and Recombinant Animal Adenoviruses in Human-Derived Cells
UB Rasmussen, M Benchaibi, V Meyer, Y Schlesinger, K Schughart
Human Gene Therapy 1999
A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells
T Dorai, H Perlman, K Walsh, A Shabsigh, ET Goluboff, CA Olsson, R Buttyan
International Journal of Cancer 1999
Fiberless recombinant adenoviruses: virus maturation and infectivity in the absence of fiber
V Legrand, D Spehner, Y Schlesinger, N Settelen, A Pavirani, M Mehtali
Journal of virology 1999
Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro
K Aoki, C Barker, X Danthinne, MJ Imperiale, GJ Nabel
Molecular Medicine 1999
Systemic correction of the muscle disorder glycogen storage disease type II after hepatic targeting of a modified adenovirus vector encoding human acid-alpha-glucosidase
A Amalfitano, AJ McVie-Wylie, H Hu, TL Dawson, N Raben, P Plotz, YT Chen
Proceedings of the National Academy of Sciences 1999
Intranuclear delivery of an antiviral peptide mediated by the B subunit of Escherichia coli heat-labile enterotoxin
A Loregian, E Papini, B Satin, HS Marsden, TR Hirst, G Palù
Proceedings of the National Academy of Sciences 1999
Gene transfection of beta 2–adrenergic receptor into the normal rat heart enhances cardiac response to beta-adrenergic agonist
Y Kawahira, Y Sawa, M Nishimura, S Sakakida, H Ueda, Y Kaneda, H Matsuda
The Journal of Thoracic and Cardiovascular Surgery 1999
Normal Perinatal Rise in Serum Cholesterol Is Inhibited by Hepatic Delivery of Adenoviral Vector Expressing Apolipoprotein B mRNA Editing Enzyme (Apobec1) in Rabbits
Y Wu, BB Teng, ML Brandt, PA Piedra, J Liu, L Chan
Journal of Surgical Research 1999
Adenoviral Gene Therapy of the Tay-Sachs Disease in Hexosaminidase A-Deficient Knock-Out Mice
JE Guidotti, A Mignon, G Haase, C Caillaud, N McDonell, A Kahn, L Poenaru
Human Molecular Genetics 1999
Ex Vivo Cell Therapy
RE Nordon, K Schindhelm
Ex Vivo Cell Therapy 1999
Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis
A Stempien-Otero, A Karsan, CJ Cornejo, H Xiang, T Eunson, RS Morrison, M Kay, R Winn, J Harlan
The Journal of biological chemistry 1999
Gene Expression Systems
R Abbud, JH Nilson
Gene Expression Systems 1999
Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia
J Herz, RD Gerard
Diabetes 1999
Age-dependent impairment of angiogenesis
JM Isner, I Baumgartner, G Rauh, R Schainfeld, R Blair, O Manor, S Razvi, JF Symes
Circulation 1999
Gene transfer into canine myoblasts
S Braun, C Thioudellet, F Perraud, C Escriou, MC Claudepierre, H Homann, M Lusky, M Mehtali, R Bischoff, A Pavirani
Cytotechnology 1999
A Cystic Fibrosis Tracheal Gland Cell Line, CF-KM4: Correction by Adenovirus-Mediated CFTR Gene Transfer
W Kammouni, B Moreau, F Becq, A Saleh, A Pavirani, C Figarella, MD Merten
American journal of respiratory cell and molecular biology 1999
Systemic correction of the muscle disorder glycogen storage disease type II after hepatic targeting of a modified adenovirus vector encoding human acid- -glucosidase
A Amalfitano, AJ McVie-Wylie, H Hu, TL Dawson, N Raben, P Plotz, YT Chen
Proceedings of the National Academy of Sciences 1999
A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors
O Corti, O Sabaté, P Horellou, P Colin, S Dumas, D Buchet, MH Buc-Caron, J Mallet
Nature Biotechnology 1999
NF-κB Activation Is Required for Human Endothelial Survival during Exposure to Tumor Necrosis Factor-α but Not to Interleukin-1β or Lipopolysaccharide
K Zen, A Karsan, A Stempien-Otero, E Yee, J Tupper, X Li, T Eunson, MA Kay, CB Wilson, RK Winn, JM Harlan
The Journal of biological chemistry 1999
Shear Stress Stimulation of p130 cas Tyrosine Phosphorylation Requires Calcium-dependent c-Src Activation
M Okuda, M Takahashi, J Suero, CE Murry, O Traub, H Kawakatsu, BC Berk
The Journal of biological chemistry 1999
Pulmonary inflammation associated with repeated, prenatal exposure to an E1, E3-deleted adenoviral vector in sheep
HS Iwamoto, BC Trapnell, CJ McConnell, C Daugherty, JA Whitsett
Gene Therapy 1999
Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein
M Themis, H Schneider, T Kiserud, T Cook, S Adebakin, S Jezzard, S Forbes, M Hanson, A Pavirani, C Rodeck, C Coutelle
Gene Therapy 1999
Temporally regulated expression patterns following in utero adenovirus-mediated gene transfer
SK Schachtner, CA Buck, JM Bergelson, HS Baldwin
Gene Therapy 1999
Neuron-restrictive silencer elements mediate neuron specificity of adenoviral gene expression
S Millecamps, H Kiefer, V Navarro, MC Geoffroy, JJ Robert, F Finiels, J Mallet, M Barkats
Nature Biotechnology 1999
Angiogenesis induced in muscle by a recombinant adenovirus expressing functional isoforms of basic fibroblast growth factor
C Garcia-Martinez, P Opolon, V Trochon, C Chianale, K Musset, H Lu, M Abitbol, M Perricaudet, T Ragot
Gene Therapy 1999
Intrauterine gene transfer: gestational stage-specific gene delivery in mice
A Türkay, TL Saunders, K Kurachi
Gene Therapy 1999
Adenovirus-mediated delivery of the Gax transcription factor to rat carotid arteries inhibits smooth muscle proliferation and induces apoptosis
H Perlman, Z Luo, K Krasinski, AL Roux, A Mahfoudi, RC Smith, D Branellec, K Walsh
Gene Therapy 1999
A model for long-term transgene expression in spinal cord regeneration studies
MT OLeary, HM Charlton
Gene Therapy 1999
Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and ΔE1B adenovirus replication in human cells
WT Steegenga, N Riteco, JL Bos
Oncogene 1999
Induction of apoptosis and G2/M arrest by infection with replication-deficient adenovirus at high multiplicity of infection
K Brand, R Klocke, A Poβling, D Paul, M Strauss
Gene Therapy 1999
Gene delivery to the myocardium by intrapericardial injection
Y Fromes, A Salmon, X Wang, H Collin, A Rouche, A Hagège, K Schwartz, MY Fiszman
Gene Therapy 1999
Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo
JC Jiménez-Chillarón, CB Newgard, AM GÓMEZ-FOIX
The FASEB Journal 1999
Somatic Gene Transfer of Human ApoA-I Inhibits Atherosclerosis Progression in Mouse Models
P Benoit, F Emmanuel, JM Caillaud, L Bassinet, G Castro, P Gallix, JC Fruchart, D Branellec, P Denèfle, N Duverger
Circulation 1999
Adenovirus-Mediated Overexpression of Tissue Inhibitor of Metalloproteinase-1 Reduces Atherosclerotic Lesions in Apolipoprotein E–Deficient Mice
M Rouis, C Adamy, N Duverger, P Lesnik, P Horellou, M Moreau, F Emmanuel, JM Caillaud, PM Laplaud, C Dachet, MJ Chapman
Circulation 1999
Efficient gene transfer and long-term expression in neurons using a recombinant adenovirus with a neuron-specific promoter
V Navarro, S Millecamps, MC Geoffroy, JJ Robert, A Valin, J Mallet, GL Salle
Gene Therapy 1999
Contemporary Concepts in Cardiology
R Gorlin, G Dangas, PK Toutouzas, MM Konstadoulakis
1999
New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet
T Ochiya, Y Takahama, S Nagahara, Y Sumita, A Hisada, H Itoh, Y Nagai, M Terada
Nature Medicine 1999
Cardiovascular Specific Gene Expression
PA Doevendans, RS Reneman, M van Bilsen
1999
Biology of the Arterial Wall
BI Levy, A Tedgui
1999
Direct Myocardial Revascularization: History, Methodology, Technology
P Whittaker, GS Abela
1999
ADENOVIRAL VECTORS FOR PROTEIN EXPRESSION
Von Seggern DJ, Nemerow GR
Gene Expression Systems 1999
A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance
R Josien, P Douillard, C Guillot, M Müschen, I Anegon, J Chetritt, S Menoret, C Vignes, JP Soulillou, MC Cuturi
Journal of Clinical Investigation 1998
Extensiveβ-Glucuronidase Activity in Murine Central Nervous System after Adenovirus-Mediated Gene Transfer to Brain
A Ghodsi, C Stein, T Derksen, G Yang, RD Anderson, BL Davidson
Human Gene Therapy 1998
Lipofectamine and Related Cationic Lipids Strongly Improve Adenoviral Infection Efficiency of Primitive Human Hematopoietic Cells
T Byk, H Haddada, W Vainchenker, F Louache
Human Gene Therapy 1998
Effects of Poloxamer 407 on Transfection Time and Percutaneous Adenovirus-Mediated Gene Transfer in Native and Stented Vessels
E Belle, L Maillard, A Rivard, JE Fabre, T Couffinhal, M Kearney, D Branellec, LJ Feldman, K Walsh, JM Isner
Human Gene Therapy 1998
Gene Therapy with Bilirubin-UDP-Glucuronosyltransferase in the Gunn Rat Model of Crigler-Najjar Syndrome Type 1
Q Li, SS Murphree, SS Willer, R Bolli, BA French
Human Gene Therapy 1998
Gene Transfer Into the Donor Heart During Cold Preservation for Heart Transplantation
SG MD, KN MD, ST MD, KN MD, SK MD
The Annals of Thoracic Surgery 1998
Gene transfer to schwann cells after peripheral nerve injury: A delivery system for therapeutic agents
J S�rensen, G Haase, C Krarup, H Gilgenkrantz, A Kahn, H Schmalbruch
Annals of Neurology 1998
Induction of DNA fragmentation and HSP72 immunoreactivity by adenovirus-mediated gene transfer in normal gerbil hippocampus and ventricle
H Kitagawa, Y Setoguchi, Y Fukuchi, Y Mitsumoto, N Koga, T Mori, K Abe
Journal of Neuroscience Research 1998
Ex Vivo and In Vivo Adenovirus-Mediated Gene Therapy Strategies Induce a Systemic Anti-Tumor Immune Defence in the B16 Melanoma Model
B Bonnekoh, DA Greenhalgh, SH Chen, A Block, SS Rich, T Krieg, SL Woo, DR Roop
Journal of Investigative Dermatology 1998
Heart-Specific Targeting ofβ-Galactosidase by the Ventricle-Specific Cardiac Myosin Light Chain 2 Promoter Using Adenovirus Vectors
F Griscelli, P Gilardi-Hebenstreit, N Hanania, WM Franz, P Opolon, M Perricaudet, T Ragot
Human Gene Therapy 1998
Sustained Expression of High Levels of Human Factor IX from Human Cells Implanted within an Immunoisolation Device into Athymic Rodents
J Brauker, GH Frost, V Dwarki, T Nijjar, R Chin, V Carr-Brendel, C Jasunas, D Hodgett, W Stone, LK Cohen, RC Johnson
Human Gene Therapy 1998
Novel Tools for Production and Purification of Recombinant Adenoassociated Virus Vectors
D Grimm, A Kern, K Rittner, JA Kleinschmidt
Human Gene Therapy 1998
Anti-Adenovirus Immune Responses in Rats Are Enhanced by Interleukin 4 but Not Interleukin 10 Produced by Recombinant Adenovirus
A David, H Coupel-Clauce, J Chetritt, L Tesson, A Cassard, B Charreau, JP Soulillou, I Anegon
Human Gene Therapy 1998
Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity
H Perlman, M Sata, AL Roux, TW Sedlak, D Branellec, K Walsh
The EMBO Journal 1998
Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases
E Li, D Stupack, GM Bokoch, GR Nemerow
Journal of virology 1998
Transient inhibition of CD28 and CD40 ligand interactions prolongs adenovirus-mediated transgene expression in the lung and facilitates expression after secondary vector administration
CB Wilson, LJ Embree, D Schowalter, R Albert, A Aruffo, D Hollenbaugh, P Linsley, MA Kay
Journal of virology 1998
The Himar1 mariner transposase cloned in a recombinant adenovirus vector is functional in mammalian cells
L Zhang, U Sankar, DJ Lampe, HM Robertson, FL Graham
Nucleic Acids Research 1998
Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest
F Griscelli, H Li, A Bennaceur-Griscelli, J Soria, P Opolon, C Soria, M Perricaudet, P Yeh, H Lu
Proceedings of the National Academy of Sciences 1998
Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver
K Jooss, HC Ertl, JM Wilson
Journal of virology 1998
Immune response to recombinant capsid proteins of adenovirus in humans: antifiber and anti-penton base antibodies have a synergistic effect on neutralizing activity
H Gahéry-Ségard, F Farace, D Godfrin, J Gaston, R Lengagne, T Tursz, P Boulanger, JG Guillet
Journal of virology 1998
In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted
M Lusky, M Christ, K Rittner, A Dieterle, D Dreyer, B Mourot, H Schultz, F Stoeckel, A Pavirani, M Mehtali
Journal of virology 1998
A simplified system for generating recombinant adenoviruses
TC He, S Zhou, LT da Costa, J Yu, KW Kinzler, B Vogelstein
Proceedings of the National Academy of Sciences 1998
Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted
A Amalfitano, MA Hauser, H Hu, D Serra, CR Begy, JS Chamberlain
Journal of virology 1998
Adenoviral gene transfer to spinal cord neurons: intrathecal vs. intraparenchymal administration
AJ Mannes, RM Caudle, BC O'Connell, MJ Iadarola
Brain Research 1998
Adenovirus-Mediated Transfer of the Acid  -Glucosidase Gene into Fibroblasts, Myoblasts and Myotubes from Patients with Glycogen Storage Disease Type II Leads to High Level Expression of Enzyme and Corrects Glycogen Accumulation
MP Nicolino, JP Puech, EJ Kremer, AJ Reuser, C Mbebi, M Verdiere-Sahuque, A Kahn, L Poenaru
Human Molecular Genetics 1998
Angiostatin gene transfer: Inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest
F Griscelli, H Li, A Bennaceur-Griscelli, J Soria, P Opolon, C Soria, M Perricaudet, P Yeh, H Lu
Proceedings of the National Academy of Sciences 1998
Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion
C A Mack, C J Magovern, K T Budenbender, S R Patel, E A Schwarz, P Zanzonico, B Ferris, T Sanborn, P Isom, B Ferris, T Sanborn, O W Isom, R G Crystal, T K Rosengart
Journal of Vascular Surgery 1998
Cells of the Neuronal Lineage Play a Major Role in the Generation of Amyloid Precursor Fragments in Gelsolin-related Amyloidosis
T Paunio, H Kangas, O Heinonen, MH Buc-Caron, JJ Robert, S Kaasinen, I Julkunen, J Mallet, L Peltonen
The Journal of biological chemistry 1998
Cell polarity, phagocytosis and viral gene transfer in cultured human retinal pigment epithelial cells
L Cruz, T Robertson, MO Hall, IJ Constable, PE Rakoczy
Current Eye Research 1998
Treatment of thromboangiitis obliterans (Buerger's disease) by intramuscular gene transfer of vascular endothelial growth factor: Preliminary clinical results
JM Isner, I Baumgartner, G Rauh, R Schainfeld, R Blair, O Manor, S Razvi, JF Symes
Circulation 1998
GATA-6 Induces p21 Cip1 Expression and G 1 Cell Cycle Arrest
H Perlman, E Suzuki, M Simonson, RC Smith, K Walsh
The Journal of biological chemistry 1998
The Long Term Adenoviral Expression of the Human Amyloid Precursor Protein Shows Different Secretase Activities in Rat Cortical Neurons and Astrocytes
AF Macq, C Czech, R Essalmani, JP Brion, A Maron, L Mercken, L Pradier, JN Octave
The Journal of biological chemistry 1998
Constitutive Expression of phVEGF 165 After Intramuscular Gene Transfer Promotes Collateral Vessel Development in Patients With Critical Limb Ischemia
I Baumgartner, A Pieczek, O Manor, R Blair, M Kearney, K Walsh, JM Isner
Circulation 1998
The Ischemic Heart
S Mochizuki, N Takeda, M Nagano, NS Dhalla
1998
An in Vivo Model for Elucidation of the Mechanism of Tumor Necrosis Factor-α (TNF-α)-Induced Insulin Resistance: Evidence for Differential Regulation of Insulin Signaling by TNF-α
AT Cheung, D Ree, JK Kolls, J Fuselier, DH Coy, M Bryer-Ash
Endocrinology 1998
Immunotherapy for Medullary Thyroid Carcinoma by a Replication-Defective Adenovirus Transducing Murine Interleukin-2
R Zhang, K Minemura, LJ Groot
Endocrinology 1998
Adenovirus Endocytosis via α v Integrins Requires Phosphoinositide-3-OH Kinase
E Li, D Stupack, R Klemke, DA Cheresh, GR Nemerow
Journal of virology 1998
Efficient, Repeated Adenovirus-Mediated Gene Transfer in Mice Lacking both Tumor Necrosis Factor Alpha and Lymphotoxin α
K Benihoud, I Saggio, P Opolon, B Salone, F Amiot, E Connault, C Chianale, F Dautry, P Yeh, M Perricaudet
Journal of virology 1998
Developmental remodeling and shortening of the cardiac outflow tract involves myocyte programmed cell death
M Watanabe, A Choudhry, M Berlan, A Singal, E Siwik, S Mohr, SA Fisher
Development (Cambridge, England) 1998
Adenovirus mediated gene therapy in a glioblastoma vaccine model; specific antitumor immunity and abrogation of immunosuppression
A M Donson, N K Foreman
Journal of Neuro-Oncology 1998
Prevention of bleomycin-induced pulmonary fibrosis after adenovirus-mediated transfer of the bacterial bleomycin resistance gene
PL Tran, J Weinbach, P Opolon, G Linares-Cruz, JP Reynes, A Grégoire, E Kremer, H Durand, M Perricaudet
Journal of Clinical Investigation 1997
In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat
K Suzuki, Y Sawa, Y Kaneda, H Ichikawa, R Shirakura, H Matsuda
Journal of Clinical Investigation 1997
Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo
R Agah, PA Frenkel, BA French, LH Michael, PA Overbeek, MD Schneider
Journal of Clinical Investigation 1997
Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication
T Schöneberg, V Sandig, J Wess, T Gudermann, G Schultz
Journal of Clinical Investigation 1997
Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products
H Gahéry-Ségard, V Molinier-Frenkel, CL Boulaire, P Saulnier, P Opolon, R Lengagne, E Gautier, AL Cesne, L Zitvogel, A Venet, C Schatz, M Courtney, TL Chevalier, T Tursz, JG Guillet, F Farace
Journal of Clinical Investigation 1997
Trypanosoma cruzi infection does not impair major histocompatibility complex class I presentation of antigen to cytotoxic T lymphocytes
FS Buckner, BT Wipke, WC van Voorhis
European Journal of Immunology 1997
Retroviral Transfer of Acidα-Glucosidase cDNA to Enzyme-Deficient Myoblasts Results in Phenotypic Spread of the Genotypic Correction by Both Secretion and Fusion
JZ Zaretsky, F Candotti, C Boerkoel, EM Adams, JW Yewdell, RM Blaese, PH Plotz
Human Gene Therapy 1997
Vasomotor Dysfunction Early after Exposure of Normal Rabbit Arteries to an Adenoviral Vector
A Lafont, G Loirand, P Pacaud, F Vilde, P Lemarchand, D Escande
Human Gene Therapy 1997
Induction of a cAMP–Stimulated Chloride Secretion in Regenerating Poorly Differentiated Airway Epithelial Cells by Adenovirus-Mediated CFTR Gene Transfer
F Dupuit, T Chinet, JM Zahm, D Pierrot, J Hinnrasky, H Kaplan, N Bonnet, E Puchelle
Human Gene Therapy 1997
Adenoviral preterminal protein stabilizes mini-adenoviral genomes in vitro and in vivo
A Lieber, CY He, MA Kay
Nature Biotechnology 1997
In vivo gene transfer and overexpression of focal adhesion kinase (pp125 FAK) mediated by recombinant adenovirus-induced tendon adhesion formation and epitenon cell change
J Lou, H Kubota, S Hotokezaka, FJ Ludwig, PR Manske
Journal of Orthopaedic Research 1997
Adenovirus-Mediated Gene Transfer into Isolated Mouse Adult Pancreatic Islets: Normalβ-Cell Function Despite Induction of an Anti-Adenovirus Immune Response
J Sigalla, A David, I Anegon, M Fiche, JM Huvelin, F Boeffard, A Cassard, JP Soulillou, BL Mauff
Human Gene Therapy 1997
Functional Consequences of Adenovirus-Mediated Murine Pancreatic Gene Transfer
SJ McClane, TE Hamilton, CV Burke, SE Raper
Human Gene Therapy 1997
Two-Step Delivery of Retroviruses to Postmitotic, Terminally Differentiated Cells
M Ito, L Kedes
Human Gene Therapy 1997
Modulation of the Specificity and Activity of a Cellular Promoter in an Adenoviral Vector
Q Shi, Y Wang, R Worton
Human Gene Therapy 1997
Efficient Adenovirus-Mediated Ectopic Gene Expression of Human Lipoprotein Lipase in Human Hepatic (HepG2) Cells
G Liu, KJ Excoffon, P Benoit, DG Ginzinger, L Miao, E Ehrenborg, N Duverger, PP Denefle, MR Hayden, ME Lewis
Human Gene Therapy 1997
Strategic gene transfer into the kidney: Current status and prospects
M Kitamura
Clinical and Experimental Nephrology 1997
Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
G Haase, P Kennel, B Pettmann, E Vigne, S Akli, F Revah, H Schmalbruch, A Kahn
Nature Medicine 1997
In vivo adenovirus-mediated gene transfer and the expression in ischemic and reperfused rat brain
K Abe, Y Setoguchi, T Hayashi, Y Itoyama
Brain Research 1997
Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons
C Gravel, R Götz, A Lorrain, M Sendtner
Nature Medicine 1997
Prevention of motoneuron death by adenovirus-mediated neurotrophic factors
MG Ribotta, F Revah, L Pradier, I Loquet, J Mallet, A Privat
Journal of Neuroscience Research 1997
Inhibition of the growth of pre-established subcutaneous tumor nodules of human prostate cancer cells by single injection of the recombinant adenovirus p53 expression vector
K Asgari, IA Sesterhenn, DG McLeod, K Cowan, JW Moul, P Seth, S Srivastava
International Journal of Cancer 1997
Efficient introduction of genes into human ovarian surface epithelium
EH Leung, BR Davies, PC Leung, GT Chen, CD Roskelley, N Auersperg
In Vitro Cellular & Developmental Biology - Animal 1997
Gene transfer into mouse embryonic stem cell-derived cardiac myocytes mediated by recombinant adenovirus
EM Rust, MV Westfall, LC Samuelson, JM Metzger
In Vitro Cellular & Developmental Biology - Animal 1997
Intrastriatal grafts of embryonic mesencephalic rat neurons genetically modified using an adenovirus encoding human Cu/Zn superoxide dismutase
M Barkats, N Nakao, EM Grasbon-Frodl, A Bilang-Bleuel, F Revah, J Mallet, P Brundin
Neuroscience 1997
Transductional Efficacy and Safety of an Intraperitoneally Delivered Adenovirus Encoding an Anti-erbB-2 Intracellular Single-Chain Antibody for Ovarian Cancer Gene Therapy
J Deshane, GP Siegal, M Wang, M Wright, RP Bucy, RD Alvarez, DT Curiel
Gynecologic Oncology 1997
Adenoviras-mediated expression of human CD59 on xenogeneic endothelial cells: Protection against human complement-mediated lysis and induction of cellular activation by adenoviral transduction
B Charreau, L Tesson, A David, A Cassard, B Quantin, A Pavirani, JP Soulillou, I Anegon
Xenotransplantation 1997
Enhancement of Humoral Immunity to SIVenv Following Simultaneous Inoculation of Mice by Three Recombinant Adenoviruses Encoding SIVenv/Poliovirus Chimeras, Tat and Rev
N Chenciner, V Randrianarison-Jewtoukoff, F Delpeyroux, N Hanania, LP Martins, LS Perricaudet, M Perricaudet, S Wain-Hobson
AIDS Research and Human Retroviruses 1997
Histochemical Staining FollowingLacZGene Transfer Underestimates Transfection Efficiency
T Couffinhal, M Kearney, A Sullivan, M Silver, Y Tsurumi, JM Isner
Human Gene Therapy 1997
Promoter Attenuation in Gene Therapy: Interferon-γand Tumor Necrosis Factor-αInhibit Transgene Expression
L Qin, Y Ding, DR Pahud, E Chang, MJ Imperiale, JS Bromberg
Human Gene Therapy 1997
Characterization of the Immune Response After Local Delivery of Recombinant Adenovirus in Murine Pancreas and Successful Strategies for Readministration
SJ McClane, N Chirmule, CV Burke, SE Raper
Human Gene Therapy 1997
Mechanism of adenovirus improvement of cationic liposome-mediated gene transfer
C Meunier-Durmort, R Picart, T Ragot, M Perricaudet, B Hainque, C Forest
Biochimica et Biophysica Acta (BBA) - Biomembranes 1997
Adenoviral vectors: development and application
WW Zhang
Expert Opinion on Investigational Drugs 1997
Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo
N Oudrhiri, JP Vigneron, M Peuchmaur, T Leclerc, JM Lehn, P Lehn
Proceedings of the National Academy of Sciences 1997
Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease
A Bilang-Bleuel, F Revah, P Colin, I Locquet, JJ Robert, J Mallet, P Horellou
Proceedings of the National Academy of Sciences 1997
Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses
JF Dedieu, E Vigne, C Torrent, C Jullien, I Mahfouz, JM Caillaud, N Aubailly, C Orsini, JM Guillaume, P Opolon, P Delaere, M Perricaudet, P Yeh
Journal of virology 1997
Cre-mediated somatic site-specific recombination in mice
K Akagi, V Sandig, M Vooijs, MV der Valk, M Giovannini, M Strauss, A Berns
Nucleic Acids Research 1997
Recombinational construction in Escherichia coli of infectious adenoviral genomes
J Crouzet, L Naudin, C Orsini, E Vigne, L Ferrero, AL Roux, P Benoit, M Latta, C Torrent, D Branellec, P Denèfle, JF Mayaux, M Perricaudet, P Yeh
Proceedings of the National Academy of Sciences 1997
Transplantation of genetically marked cardiac muscle cells
S Gojo, S Kitamura, O Hatano, A Takakusu, K Hashimoto, Y Kanegae, I Saito
The Journal of Thoracic and Cardiovascular Surgery 1997
Adenovirus-mediated suicide gene therapy for experimental bladder cancer
MA Sutton, SA Berkman, SH Chen, A Block, TD Dang, MW Kattan, TM Wheeler, DR Rowley, SL Woo, SP Lerner
Urology 1997
Engineering Tissue-Specific Expression of a Recombinant Adenovirus: Selective Transgene Transcription in the Pancreas Using the Amylase Promoter
RP Dematteo, SJ McClane, K Fisher, H Yeh, G Chu, C Burke, SE Raper
Journal of Surgical Research 1997
Dissociative expression of adenoviral-mediated E. coli LacZ gene between ischemic and reperfused rat brains
K Abe, Y Setoguchi, T Hayashi, Y Itoyama
Neuroscience Letters 1997
Adenovirus-mediated myofilament gene transfer into adult cardiac myocytes
MV Westfall, EM Rust, F Albayya, JM Metzger
Methods in cell biology 1997
Expression from cardiomyocyte-specific promoter after adenovirus-mediated gene transfer in vitro and in vivo
F Griscelli, P Opolon, C Chianale, ND Falco, WM Franz, M Perricaudet, T Ragot
Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie 1997
Intracoronary gene transfer of immunosuppressive cytokines to cardiac allografts: Method and efficacy of adenovirus-mediated transduction
R Brauner, L Wu, H Laks, M Nonoyama, F Scholl, O Shvarts, A Berk, DC Drinkwater, JL Wang
The Journal of Thoracic and Cardiovascular Surgery 1997
Efficient Transfer of Genes into Senescent Cells by Adenovirus Vectors via Highly Expressed αvβ5 Integrin
Y Hashimoto, K Kohri, H Akita, K Mitani, K Ikeda, M Nakanishi
Biochemical and Biophysical Research Communications 1997
Adenoviral Vectors for Hepatic Gene Transfer in Animals
MA Kay
Chest 1997
Adenovirus-Mediated Transfer of a Dominant-Negative H- ras Suppresses Neointimal Formation in Balloon-Injured Arteries In Vivo
H Ueno, H Yamamoto, S Ito, JJ Li, A Takeshita
Arteriosclerosis, thrombosis, and vascular biology 1997
Gene Transfer in the Cardiovascular System
KL March
1997
Correction of Hypertriglyceridemia and Impaired Fat Tolerance in Lipoprotein Lipase–Deficient Mice by Adenovirus-Mediated Expression of Human Lipoprotein Lipase
KJ Excoffon, G Liu, L Miao, JE Wilson, BM McManus, CF Semenkovich, T Coleman, P Benoit, N Duverger, D Branellec, P Denefle, MR Hayden, ME Lewis
Arteriosclerosis, thrombosis, and vascular biology 1997
In Utero Cardiac Gene Transfer via Intraplacental Delivery of Recombinant Adenovirus
YJ Woo, GP Raju, JL Swain, ME Richmond, TJ Gardner, RJ Balice-Gordon
Circulation 1997
Forced expression of the homeodomain protein Gax inhibits cardiomyocyte proliferation and perturbs heart morphogenesis
SA Fisher, E Siwik, D Branellec, K Walsh, M Watanabe
Development (Cambridge, England) 1997
Efficient introduction of genes into human ovarian surface epithelium
EH Leung, BR Davies, PC Leung, GT Chen, CD Roskelley, N Auersperg
In vitro cellular & developmental biology. Animal 1997
Gene transfer into mouse embryonic stem cell-derived cardiac myocytes mediated by recombinant adenovirus
EM Rust, MV Westfall, LC Samuelson, JM Metzger
In vitro cellular & developmental biology. Animal 1997
Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with MyoD
CE Murry, MA Kay, T Bartosek, SD Hauschka, SM Schwartz
Journal of Clinical Investigation 1996
Adenoviral infection of thyroid cells: A rationale for gene therapy for metastatic thyroid carcinoma
MA Zeiger, Y Takiyama, JO Bishop, AR Ellison, M Saji, MA Levine
Surgery 1996
Sustained somatic gene inactivation by viral transfer of Cre recombinase
A Rohlmann, M Gotthardt, TE Willnow, RE Hammer, J Herz
Nature Biotechnology 1996
Gene transfer into the kidney: Promise for unravelling disease mechanisms, limitations for human gene therapy
LG Fine
Kidney International 1996
Arterial Gene Transfer for Therapeutic Angiogenesis in Patients with Peripheral Artery Disease. St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts
JM Isner, K Walsh, J Symes, A Pieczek, S Takeshita, J Lowry, K Rosenfield, L Weir, E Brogi, D Jurayj
Human Gene Therapy 1996
Gene Therapy in Lung Transplantation: Feasibility ofEx VivoAdenovirus-Mediated Gene Transfer to the Graft
A Chapelier, C Danel, M Mazmanian, EA Bacha, H Sellak, MA Gilbert, P Hervé, P Lemarchand
Human Gene Therapy 1996
In VivoExpression of Full-Length Human Dystrophin from Adenoviral Vectors Deleted of All Viral Genes
SE Haecker, HH Stedman, RJ Balice-Gordon, DB Smith, JP Greelish, MA Mitchell, A Wells, HL Sweeney, JM Wilson
Human Gene Therapy 1996
Dystrophin Expression in Muscles of mdx Mice After Adenovirus-MediatedIn VivoGene Transfer
G Acsadi, H Lochmüller, A Jani, J Huard, B Massie, S Prescott, M Simoneau, BJ Petrof, G Karpati
Human Gene Therapy 1996
Characterization of 911: A New Helper Cell Line for the Titration and Propagation of Early Region 1-Deleted Adenoviral Vectors
FJ Fallaux, O Kranenburg, SJ Cramer, A Houweling, H Ormondt, RC Hoeben, AJ van der Eb
Human Gene Therapy 1996
Adenovirus-Mediated Hepatic Gene Transfer in Mice: Comparison of Intravascular and Biliary Administration
MJ Peeters, GA Patijn, A Lieber, L Meuse, MA Kay
Human Gene Therapy 1996
Cardiovascular Gene Therapy: Current Concepts
JC Fox
Therapeutic Drug Monitoring 1996
Targeted gene delivery by tropism-modified adenoviral vectors
JT Douglas, BE Rogers, ME Rosenfeld, SI Michael, M Feng, DT Curiel
Nature Biotechnology 1996
A method to codetect introduced genes and their products in gene therapy protocols
E Gussoni, Y Wang, C Fraefel, RG Miller, HM Blau, AI Geller, LM Kunkel
Nature Biotechnology 1996
Efficient Transfer of Regulated Genes in Adipocytes and Hepatoma Cells by the Combination of Liposomes and Replication-Deficient Adenovirus
C Meunier-Durmort, N Ferry, B Hainque, J Delattre, C Forest
European Journal of Biochemistry 1996
Adenoviral-Mediated Herpes Simplex Virus-Thymidine Kinase Gene Transfer in Vivo for Treatment of Experimental Human Melanoma
B Bonnekoh, DA Greenhalgh, DS Bundman, K Kosai, SH Chen, MJ Finegold, T Krieg, SL Woo, DR Roop
Journal of Investigative Dermatology 1996
Adenovirus-mediated gene transfer into tendon and tendon sheath
J Lou, PR Manske, M Aoki, ME Joyce
Journal of Orthopaedic Research 1996
Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A
G Warnier, MT Duffour, C Uyttenhove, TF Gajewski, C Lurquin, H Haddada, M Perricaudet, T Boon
International Journal of Cancer 1996
Immunological approaches in the gene therapy of cancer
T Tursz
The Breast 1996
Prostate Cancer Gene Therapy: Herpes Simplex Virus Thymidine Kinase Gene Transduction Followed by Ganciclovir in Mouse and Human Prostate Cancer Models
JA Eastham, SH Chen, I Sehgal, G Yang, TL Timme, SJ Hall, SL Woo, TC Thompson
Human Gene Therapy 1996
Phase Ia Trial of a Polynucleotide Anti-Tumor Immunization to Human Carcinoembryonic Antigen in Patients with Metastatic Colorectal Cancer. University of Alabama at Birmingham, Birmingham, Alabama
RM Conry, AF LoBuglio, DT Curiel
Human Gene Therapy 1996
Herpes Simplex Virus Thymidine Kinase Gene Therapy for Rat Malignant Brain Tumors
AJ Vincent, R Vogels, GV Someren, MC Esandi, JL Noteboom, CJ Avezaat, C Vecht, DW Bekkum, D Valerio, A Bout, PM Hoogerbrugge
Human Gene Therapy 1996
In VitroAssessment of Variables Affecting the Efficiency and Efficacy of Adenovirus-Mediated Gene Transfer to Cystic Fibrosis Airway Epithelia
LG Johnson, RJ Pickles, SE Boyles, JC Morris, H Ye, Z Zhou, JC Olsen, RC Boucher
Human Gene Therapy 1996
In VitroandIn VivoHepatoma Cell-Specific Expression of a Gene Transferred with an Adenoviral Vector
PB Arbuthnot, MP Bralet, CL Jossic, JF Dedieu, M Perricaudet, C Bréchot, N Ferry
Human Gene Therapy 1996
Non-replicating expression vectors: applications in vaccine development and gene therapy
KJ Limbach, E Paoletti
Epidemiology and Infection 1996
Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells
S Huang, T Kamata, Y Takada, ZM Ruggeri, GR Nemerow
Journal of virology 1996
Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic protein
PD Kessler, GM Podsakoff, X Chen, SA McQuiston, PC Colosi, LA Matelis, GJ Kurtzman, BJ Byrne
Proceedings of the National Academy of Sciences 1996
Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted
H Zhou, W O'Neal, N Morral, AL Beaudet
Journal of virology 1996
Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism
VN Krasnykh, GV Mikheeva, JT Douglas, DT Curiel
Journal of virology 1996
Functional protection of dystrophic mouse (mdx) muscles after adenovirus-mediated transfer of a dystrophin minigene
N Deconinck, T Ragot, G Maréchal, M Perricaudet, JM Gillis
Proceedings of the National Academy of Sciences 1996
Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors
A Amalfitano, CR Begy, JS Chamberlain
Proceedings of the National Academy of Sciences 1996
Successful expression of human factor IX following repeat administration of adenoviral vector in mice
J Walter, Q You, JN Hagstrom, M Sands, KA High
Proceedings of the National Academy of Sciences 1996
Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit
P Yeh, JF Dedieu, C Orsini, E Vigne, P Denefle, M Perricaudet
Journal of virology 1996
Gene-based therapeutic strategies for Human Lipoprotein Lipase (LPL) deficiency: Rationale and prospects for alteration of atherogenic risk
ME Lewis, G Liu, DG Ginzinger, P Benoit, SD Jones, KJ Ashbourne, JE Wilson, BM McManus, N Duverger, PP Denefle, MR Hayden
Transfusion Science 1996
Recombinant human adenovirus with rat MIP-2 gene insertion causes prolonged PMN recruitment to the murine brain
MD Bell, DD Taub, SJ Kunkel, RM Strieter, R Foley, J Gauldie, VH Perry
The European journal of neuroscience 1996
Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart
FJ Giordano, P Ping, MD McKirnan, S Nozaki, AN DeMaria, WH Dillmann, O Mathieu-Costello, HK Hammond
Nature Medicine 1996
GENE THERAPY AND INHERITED DYSLIPIDEMIA
TO MD
Endocrine Practice 1996
Utilisation des virus comme vecteurs de thérapie génique
M Latta, M Perricaudet, P Yeh
Revue Française des Laboratoires 1996
Gene transfer by adenovirus in smooth muscle cells
MF Yu, JI Ewaskiewicz, S Adda, K Bailey, V Harris, D Sosnoski, M Tomasic, J Wilson, MI Kotlikoff
Respiration Physiology 1996
Prospects of gene therapy for genetic skeletal muscle disease
G Karpati, H Lochmuller
Transfusion Science 1996
Cardiac gene transfer by intracoronary infusion of adenovirus vector—mediated reporter gene in the transplanted mouse heart
J Lee, H Laks, DC Drinkwater, A Blitz, L Lam, Y Shiraishi, P Chang, TA Drake, A Ardehali
The Journal of Thoracic and Cardiovascular Surgery 1996
Retroviral vectors to study cardiovascular development
T Mikawa, J Hyer, N Itoh, Y Wei
Trends in Cardiovascular Medicine 1996
ADENOVIRUS-MEDIATED GENE TRANSFER INTO RAT CARDIAC ALLOGRAFTS: Comparison of Direct Injection and Perfusion1
J Wang, Y NA, SJ Knechtle
Transplantation 1996
Potential Gene Therapy for Lecithin-Cholesterol Acyltransferase (LCAT)–Deficient and Hypoalphalipoproteinemic Patients With Adenovirus-Mediated Transfer of Human LCAT Gene
S Seguret-Mace, M Latta-Mahieu, G Castro, G Luc, JC Fruchart, E Rubin, P Denefle, N Duverger
Circulation 1996
Avoidance of Immune Response Prolongs Expression of Genes Delivered to the Adult Rat Myocardium by Replication-Defective Adenovirus
MJ Quinones, J Leor, RA Kloner, M Ito, M Patterson, WF Witke, L Kedes
Circulation 1996
Chirurgisches Forum ’96 fur experimentelle und klinische Forschung
HG Beger, D Birk, L Staib, R Pichlmayr, J Seifert, W Hartel
1996
Triggering of Acute Coronary Syndromes
SN Willich, JE Muller
1996
Yearbook of Cell and Tissue Transplantation 1996–1997
RP Lanza, WL Chick
1996
59. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie e.V
G Muhr, KE Rehm
1996
Targeting of Drugs 5
G Gregoriadis, B McCormack
1996
Genetic Approaches to Noncommunicable Diseases
K Berg, V Boulyjenkov, Y Christen
1996
Gene Therapy for Plastic and Reconstructive Surgery
SM Shenaq, ED Rabinovsky
Clinics in Plastic Surgery 1996
Strategies for cancer gene therapy using adenoviral vectors
V Descamps, , , N Fernandez, L Cordier, MA Abina, E Kremer, M Perricaudet, H Haddada
Journal of Molecular Medicine 1996
Non-replicating expression vectors: applications in vaccine development and gene therapy.
Limbach KJ, Paoletti E
Epidemiology and Infection 1996
Targeted expression of transforming growth factor-beta 1 in intracardiac grafts promotes vascular endothelial cell DNA synthesis
GY Koh, SJ Kim, MG Klug, K Park, MH Soonpaa, LJ Field
Journal of Clinical Investigation 1995
Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo
PB McCray, K Armstrong, J Zabner, DW Miller, GA Koretzky, L Couture, JE Robillard, AE Smith, MJ Welsh
Journal of Clinical Investigation 1995
Low-efficiency of percutaneous adenovirus-mediated arterial gene transfer in the atherosclerotic rabbit
LJ Feldman, PG Steg, LP Zheng, D Chen, M Kearney, SE McGarr, JJ Barry, JF Dedieu, M Perricaudet, JM Isner
Journal of Clinical Investigation 1995
Adenovirus-mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocytes) and in vivo (rat liver). A novel strategy for modifying excitability
DC Johns, HB Nuss, N Chiamvimonvat, BM Ramza, E Marban, JH Lawrence
Journal of Clinical Investigation 1995
Regenerating Cells in Human Airway Surface Epithelium Represent Preferential Targets for Recombinant Adenovirus
F Dupuit, JM Zahm, D Pierrot, S Brezillon, N Bonnet, JL Imler, A Pavirani, E Puchelle
Human Gene Therapy 1995
Adenovirus-Mediated Gene Transfer to the Respiratory Tract of Fetal SheepIn Utero
MC Vincent, BC Trapnell, RP Baughman, SE Wert, JA Whitsett, HS Iwamoto
Human Gene Therapy 1995
Prevention of restenosis after coronary angioplasty: towards a molecular approach?
LJ Feldman, R Riessen, PG Steg
Fundamental & Clinical Pharmacology 1995
Adenovirus-Mediated Gene Transfer to the Respiratory Tract of Fetal Sheep In Utero
MC Vincent, BC Trapnell, RP Baughman, SE Wert, JA Whitsett, HS Iwamoto
Human Gene Therapy 1995
Tetracycline-regulated gene expression following direct gene transfer into mouse skeletal muscle
J Dhawan, TA Rando, SL Elson, H Bujard, HM Blau
Somatic Cell and Molecular Genetics 1995
Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses
O Sabaté, P Horellou, E Vigne, P Colin, M Perricaudet, MH Buc-Caron, J Mallet
Nature Genetics 1995
Myoblast transfer and gene therapy in muscular dystrophies
CN Pagel, JE Morgan
Microscopy Research and Technique 1995
Inhibition of Melanoma Growth by Adenoviral-Mediated HSV Thymidine Kinase Gene Transfer In Vivo
B Bonnekoh, DA Greenhalgh, DS Bundman, JN Eckhardt, MA Longley, SH Chen, SL Woo, DR Roop
Journal of Investigative Dermatology 1995
Toward a gene therapy for duchenne muscular dystrophy
MG Dunckley, TA Piper, G Dickson
Mental Retardation and Developmental Disabilities Research Reviews 1995
Prospects for Gene Therapy with Direct Injection of Polynucleotides
A Kass-Eisler, K Li, LA Leinwand
Annals of the New York Academy of Sciences 1995
Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
V Juillard, P Villefroy, D Godfrin, A Pavirani, A Venet, JG Guillet
European Journal of Immunology 1995
Prenatal gene therapy: Prospects and issues
E Pergament, M Fiddler
Prenatal Diagnosis 1995
Strategies for Myocardial Repair
GY Koh, MH Soonpaa, MG Klug, LJ Field
Journal of Interventional Cardiology 1995
Potential gene therapy strategies in the treatment of cardiovascular disease
RT Rowland, JC Cleveland, X Meng, AH Harken, JM Brown
The Annals of Thoracic Surgery 1995
Transient Expression of Genes TransferredIn Vivointo Heart Using First-Generation Adenoviral Vectors: Role of the Immune Response
H Gilgenkrantz, D Duboc, V Juillard, D Couton, A Pavirani, JG Guillet, P Briand, A Kahn
Human Gene Therapy 1995
Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery
PR Clemens, TL Krause, S Chan, KE Korb, FL Graham, CT Caskey
Human Gene Therapy 1995
Adenovirus-Mediated Transfer of the Amphotropic Retrovirus Receptor cDNA Increases Retroviral Transduction in Cultured Cells
A Lieber, MJ Peeters, MA Kay
Human Gene Therapy 1995
In utero gene transfer into the pulmonary epithelium
HS Sekhon, JE Larson
Nature Medicine 1995
Phenotype correction in retinal pigment epithelium in murine mucopolysaccharidosis VII by adenovirus-mediated gene transfer
T Li, BL Davidson
Proceedings of the National Academy of Sciences 1995
Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery
MW Chang, T Ohno, D Gordon, MM Lu, GJ Nabel, EG Nabel, JM Leiden
Molecular Medicine 1995
Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression
M Anton, FL Graham
Journal of virology 1995
Adenovirus-mediated urokinase gene transfer induces liver regeneration and allows for efficient retrovirus transduction of hepatocytes in vivo
A Lieber, MJ Peeters, L Meuse, N Fausto, J Perkins, MA Kay
Proceedings of the National Academy of Sciences 1995
Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
S Huang, RI Endo, GR Nemerow
Journal of virology 1995
The Gordon Wilson Lecture. In vivo gene therapy: a strategy to use human genes as therapeutics
RG Crystal
Transactions of the American Clinical and Climatological Association 1995
Adenovirus-rnediated expression of a reporter gene in thalamocortical cocultures
MF Wilkemeyer, KJ Angelides
Brain Research 1995
Genetic Manipulation of the Nervous System
M Heilig, KH Schlingensiepen
Genetic Manipulation of the Nervous System 1995
Liver-directed gene therapy: molecular tools and current preclinical and clinical studies
M Alt, WH Caselmann
Journal of Hepatology 1995
Molecular and Cell Biology of Human Gene Therapeutics
G Dickson
1995
Quantitative Analysis of Repeat Adenovirus-Mediated Gene Transfer Into Injured Canine Femoral Arteries
H Ueno, JJ Li, H Tomita, H Yamamoto, Y Pan, Y Kanegae, I Saito, A Takeshita
Arteriosclerosis, thrombosis, and vascular biology 1995
Cardiovascular Disease 2
LL Gallo
1995
Molecular and Subcellular Cardiology
S Sideman, R Beyar
1995
Viruses in Human Gene Therapy
JM Vos
1995
The Molecular Repertoire of Adenoviruses III
W Doerfler, P Böhm
1995
Current aspects of gene therapy: implications for vascular interventions
F Reifers, J Kreuzer
Journal of Molecular Medicine 1995
Adenovirus-mediated gene transfer into striated muscles
G Acsadi, A Jani, B Massie
Journal of Molecular Medicine 1995
Tetracycline-regulated cardiac gene expression in vivo
GI Fishman, ML Kaplan, PM Buttrick
Journal of Clinical Investigation 1994
Prospects for site-specific delivery of pharmacologic and molecular therapies
R Riessen, JM Isner
Journal of the American College of Cardiology 1994
Increasing Expression of the Normal Human CFTR cDNA in Cystic Fibrosis Epithelial Cells Results in a Progressive Increase in the Level of CFTR Protein Expression, but a Limit on the Level of cAMP-Stimulated Chloride Secretion
MA Rosenfeld, SJ Rosenfeld, C Danel, TC Banks, RG Crystal
Human Gene Therapy 1994
Gene Transfer to Human Fetal Pulmonary Tissue Developed in Immunodeficient SCID Mice
B Péault, R Tirouvanziam, MN Sombardier, S Chen, M Perricaudet, D Gaillard
Human Gene Therapy 1994
Acute Responses of Non-Human Primates to Airway Delivery of an Adenovirus Vector Containing the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA
SL Brody, M Metzger, C Danel, MA Rosenfeld, RG Crystal
Human Gene Therapy 1994
Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen
HL Davis, ML Michel, M Mancini, M Schleef, RG Whalen
Vaccine 1994
Cell and Gene Therapy in Duchenne Muscular Dystrophy
JE Morgan
Human Gene Therapy 1994
Erythropoietin Gene Transfer and Expression in Adult Normal Mice: Use of an Adenovirus Vector
V Descamps, N Blumenfeld, JL Villeval, W Vainchenker, M Perricaudet, Y Beuzard
Human Gene Therapy 1994
DirectIn VivoGene Transfer and Expression in Malignant Cells Using Adenovirus Vectors
SL Brody, HA Jaffe, SK Han, RP Wersto, RG Crystal
Human Gene Therapy 1994
Ex Vivo and In Vivo Gene Transfer to The Skin Using Replication-Deficient Recombinant Adenovirus Vectors
Y Setoguchi, HA Jaffe, C Danel, RG Crystal
Journal of Investigative Dermatology 1994
Adenoviral-mediated gene transfer to renal tubular cells in vivo
P Moullier, G Friedlander, D Calise, P Ronco, M Perricaudet, N Ferry
Kidney International 1994
Gene Therapy for Cystic Fibrosis Using E1-Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
RC Boucher, MR Knowles, LG Johnson, JC Olsen, R Pickles, JM Wilson, J Engelhardt, Y Yang, M Grossman
Human Gene Therapy 1994
Gene therapy using adenoviral vectors
BC Trapnell, M Gorziglia
Current Opinion in Biotechnology 1994
Transduction of Human Bone Marrow by Adenoviral Vector
K Mitani, FL Graham, CT Caskey
Human Gene Therapy 1994
Lung Gene Therapy:In VivoAdenovirus-Mediated Gene Transfer to Rhesus Monkey Airway Epithelium
A Bout, M Perricaudet, G Baskin, JL Imler, BJ Scholte, A Pavirani, D Valerio
Human Gene Therapy 1994
Adenovirus-mediated delivery into myocytes of muscle glycogen phosphorylase, the enzyme deficient in patients with glycogen-storage disease type V
S Baqué, CB Newgard, RD Gerard, JJ Guinovart, AM Gómez-Foix
Biochemical Journal 1994
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer
J Kolls, K Peppel, M Silva, B Beutler
Proceedings of the National Academy of Sciences 1994
Coronary restenosis and gene therapy
W Mazur, NM Ali, AE Raizner, BA French
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 1994
Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
SH Chen, HD Shine, JC Goodman, RG Grossman, SL Woo
Proceedings of the National Academy of Sciences 1994
In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs
MA Kay, CN Landen, SR Rothenberg, LA Taylor, F Leland, S Wiehle, B Fang, D Bellinger, M Finegold, AR Thompson
Proceedings of the National Academy of Sciences 1994
In vivo and in vitro analysis of electrical activity-dependent expression of muscle acetylcholine receptor genes using adenovirus
JL Bessereau, LD Stratford-Perricaudet, J Piette, CL Poupon, JP Changeux
Proceedings of the National Academy of Sciences 1994
Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus
SK Tripathy, E Goldwasser, MM Lu, E Barr, JM Leiden
Proceedings of the National Academy of Sciences 1994
Adenoviral vectors as functional retrograde neuronal tracers
V Ridoux, JJ Robert, X Zhang, M Perricaudet, J Mallet, GL la Salle
Brain Research 1994
Advances in Pharmacology
B Drenger, Y Ginosar, Y Gozal
Advances in Pharmacology 1994
Gene therapy—Its potential in the management of oral cancer
EJ Shillitoe, JN Lapeyre, K Adler-Storthz
European Journal of Cancer. Part B: Oral Oncology 1994
Use of recombinant adenovirus for metabolic engineering of mammalian cells
EV Schaftingen, B Lederer, R Bartrons, HG Hers
Methods in cell biology 1994
Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors
BA French, W Mazur, RS Geske, R Bolli
Circulation 1994
The new frontier: gene and oligonucleotide therapy
H Schreier
Pharmaceutica Acta Helvetiae 1994
Expression of a recombinant dystrophin in mdx mice using adenovirus vector
HS Alameddine, B Quantin, A Cartaud, M Dehaupas, JL Mandel, M Fardeau
Neuromuscular Disorders 1994
Adenovirus-mediated transfer of human lipase complementary DNA to the gallbladder
H Maeda, C Danel, RG Crystal
Gastroenterology 1994
Somatic gene therapy for cardiovascular disease
E Barr, JM Leiden
Trends in Cardiovascular Medicine 1994
Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosis
BA French, W Mazur, NM Ali, RS Geske, JP Finnigan, GP Rodgers, R Roberts, AE Raizner
Circulation 1994
Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterol
WP Kopfler, M Willard, T Betz, JE Willard, RD Gerard, RS Meidell
Circulation 1994
Catheter-mediated pulmonary vascular gene transfer and expression
DW Muller, D Gordon, H San, Z Yang, VJ Pompili, GJ Nabel, EG Nabel
Circulation research 1994
Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector
PG Steg, LJ Feldman, JY Scoazec, O Tahlil, JJ Barry, S Boulechfar, T Ragot, JM Isner, M Perricaudet
Circulation 1994
Gene Therapeutics
JA Wolff
1994
Hepatic Encephalopathy, Hyperammonemia, and Ammonia Toxicity
V Felipo, S Grisolia
1994
In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
KF Kozarsky, DR McKinley, LL Austin, SE Raper, LD Stratford-Perricaudet, JM Wilson
The Journal of biological chemistry 1994
Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer
A Mastrangeli, C Danel, MA Rosenfeld, L Stratford-Perricaudet, M Perricaudet, A Pavirani, JP Lecocq, RG Crystal
Journal of Clinical Investigation 1993
Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes
MA Morsy, EL Alford, A Bett, FL Graham, CT Caskey
Journal of Clinical Investigation 1993
Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1–deleted adenoviruses
JF Engelhardt, Y Yang, LD Stratford-Perricaudet, ED Allen, K Kozarsky, M Perricaudet, JR Yankaskas, JM Wilson
Nature Genetics 1993
Gene therapy for duchenne dystrophy
AG Engel
Annals of Neurology 1993
Arterial Gene Transfer Using Pure DNA Applied Directly to a Hydrogel-Coated Angioplasty Balloon
R Riessen, H Rahimizadeh, E Blessing, S Takeshita, JJ Barry, JM Isner
Human Gene Therapy 1993
Adenoviral Interleukin-2 Gene Transfer into P815 Tumor Cells Abrogates Tumorigenicity and Induces Antitumoral Immunity in Mice
H Haddada, T Ragot, L Cordier, MT Duffour, M Perricaudet
Human Gene Therapy 1993
Adenoviral Vector as a Gene Delivery System into Cultured Rat Neuronal and Glial Cells
C Caillaud, S Akli, E Vigne, A Koulakoff, M Perricaudet, L Poenaru, A Kahn, Y Berwald-Netter
European Journal of Neuroscience 1993
Long–term correction of mouse dystrophic degeneration by adenovirus–mediated transfer of a minidystrophin gene
N Vincent, T Ragot, H Gilgenkrantz, D Couton, P Chafey, A Grégoire, P Briand, JC Kaplan, A Kahn, M Perricaudet
Nature Genetics 1993
Transfer of a foreign gene into the brain using adenovirus vectors
S Akli, C Caillaud, E Vigne, LD Stratford-Perricaudet, L Poenaru, M Perricaudet, A Kahn, MR Peschanski
Nature Genetics 1993
Delivering therapeutic genes — matching approach and application
K Mitani, CT Caskey
Trends in Biotechnology 1993
Assessment of Recombinant Adenoviral Vectors for Hepatic Gene Therapy
Q Li, MA Kay, M Finegold, LD Stratford-Perricaudet, SL Woo
Human Gene Therapy 1993
Direct Gene Transfer into Skeletal MuscleIn Vivo: Factors Affecting Efficiency of Transfer and Stability of Expression
HL Davis, RG Whalen, BA Demeneix
Human Gene Therapy 1993
Plasmid DNA Is Superior to Viral Vectors for Direct Gene Transfer into Adult Mouse Skeletal Muscle
HL Davis, BA Demeneix, B Quantin, J Coulombe, RG Whalen
Human Gene Therapy 1993
Human genetic therapy
J Harris, K Sikora
Molecular Aspects of Medicine 1993
Gene therapy: adenovirus vectors
KF Kozarsky, JM Wilson
Current Opinion in Genetics & Development 1993
Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice
TA Smith, MG Mehaffey, DB Kayda, JM Saunders, S Yei, BC Trapnell, A McClelland, M Kaleko
Nature Genetics 1993
Packaging capacity and stability of human adenovirus type 5 vectors
AJ Bett, L Prevec, FL Graham
Journal of virology 1993
Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo
A Kass-Eisler, E Falck-Pedersen, M Alvira, J Rivera, PM Buttrick, BA Wittenberg, L Cipriani, LA Leinwand
Proceedings of the National Academy of Sciences 1993
Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants
M Cotten, E Wagner, K Zatloukal, ML Birnstiel
Journal of virology 1993
Direct gene transfer into mouse diaphragm
HL Davis, BJ Jasmin
FEBS Letters 1993
An adenovirus vector for gene transfer into neurons and glia in the brain
GL la Salle, J Robert, S Berrard, V Ridoux, L Stratford-Perricaudet, M Perricaudet, J Mallet
Science 1993
The basic science of gene therapy
RC Mulligan
Science 1993
Overview: In Vivo Expression of Human Genes
AE Canonico, KL Brigham
Current Opinion on Therapeutic Patents 1993
Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice
T Ragot, N Vincent, P Chafey, E Vigne, H Gilgenkrantz, D Coutont, J Cartaud, P Briand, JC Kaplant, M Perricaude, A Kahn
Nature 1993
Regulation of myosin heavy chain genes in the heart
E Morkin
Circulation 1993
Efficient and selective adenovirus-mediated gene transfer into vascular neointima
RJ Guzman, P Lemarchand, RG Crystal, SE Epstein, T Finkel
Circulation 1993
Efficient gene transfer into myocardium by direct injection of adenovirus vectors
RJ Guzman, P Lemarchand, RG Crystal, SE Epstein, T Finkel
Circulation research 1993
In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries
SW Lee, BC Trapnell, JJ Rade, R Virmani, DA Dichek
Circulation research 1993
In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors
P Lemarchand, M Jones, I Yamada, RG Crystal
Circulation research 1993
The advent of adenovirus. Gene therapy for cardiovascular disease
MD Schneider, BA French
Circulation 1993
Adenovirus–mediated in vivo gene transfer and expression in normal rat liver
HA Jaffe, C Danel, G Longenecker, M Metzger, Y Setoguchi, MA Rosenfeld, TW Gant, SS Thorgeirsson, LD Stratford-Perricaudet, M Perricaudet, A Pavirani, JP Lecocq, RG Crystal
Nature Genetics 1992
Advances in Genetics
BH Bowman, F Yang, GS Adrian
Advances in genetics 1988

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