JCI - Citations to cDNA cloning of human plasminogen activator-inhibitor from endothelial cells.

Citations to this article

cDNA cloning of human plasminogen activator-inhibitor from endothelial cells.

D Ginsburg, … , R V Lebo, T D Gelehrter

D Ginsburg, … , R V Lebo, T D Gelehrter

Published December 1, 1986
Citation Information: J Clin Invest. 1986;78(6):1673-1680. https://doi.org/10.1172/JCI112761.

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Citations to this article (260)

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Clinical impact of the PAI-1 4G/5G polymorphism in Chinese patients with venous thromboembolism. Wang Z, Kong L, Luo G, Zhang H, Sun F, Liang W, Wu W, Guo Z, Zhang R, Dou Y	Thrombosis Journal	2022
Plasmin and Plasminogen System in the Tumor Microenvironment: Implications for Cancer Diagnosis, Prognosis, and Therapy AG Bharadwaj, RW Holloway, VA Miller, DM Waisman	Cancers	2021
PAI-1, the Plasminogen System, and Skeletal Muscle FA Rahman, MP Krause	International journal of molecular sciences	2020
Plasminogen activator inhibitor‐1: a potential etiological role in livedoid vasculopathy Y Gao, H Jin	International Wound Journal	2020
Role of plasminogen activator inhibitor-1 in coronary pathophysiology RG Jung, T Simard, A Labinaz, FD Ramirez, PD Santo, P Motazedian, R Rochman, C Gaudet, MA Faraz, RS Beanlands, B Hibbert	Thrombosis Research	2018
Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of SenescenceHighlights DE Vaughan, R Rai, SS Khan, M Eren, AK Ghosh	Arteriosclerosis, thrombosis, and vascular biology	2017
Encyclopedia of Signaling Molecules S Choi	Encyclopedia of Signaling Molecules	2016
Functional Stability of Plasminogen Activator Inhibitor-1 SY Yildiz, P Kuru, ET Oner, M Agirbasli	The Scientific World JOURNAL	2014
The plasminogen activation system in periodontal tissue (Review) M Wyganowska-Świątkowska, A Surdacka, E Skrzypczak-Jankun, J Jankun	International journal of molecular medicine	2014
Genetic background of idiopathic pulmonary fibrosis S Santangelo, S Scarlata, A Zito, D Chiurco, C Pedone, RA Incalzi	Expert Review of Molecular Diagnostics	2013
The obstetric, gynaecological and fertility implications of homozygous PAI-1 deficiency: single-centre experience M Heiman, S Gupta, AD Shapiro	Haemophilia	2013
Sputum Plasminogen Activator Inhibitor-1 Elevation by Oxidative Stress-Dependent Nuclear Factor-κB Activation in COPD M To, D Takagi, K Akashi, I Kano, K Haruki, PJ Barnes, K Ito	Chest	2013
Impact of the -675 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene on childhood IgA nephropathy SR Han, CJ Kim, BC Lee	Experimental and therapeutic medicine	2012
Methods in Enzymology JD Stone, AS Chervin, DH Aggen, DM Kranz	Protein Engineering for Therapeutics Part B	2012
Hémostase locale en chirurgie orale. 1<sup>ère</sup> partie : physiologie de l’hémostase Y Nizamaldin, SA Najm, ME Hage, J Samson	Médecine Buccale Chirurgie Buccale	2012
Posttranscriptional regulation of expression of plasminogen activator inhibitor type-1 by sphingosine 1-phosphate in HepG2 liver cells S Iwaki, S Yamamura, M Asai, BE Sobel, S Fujii	Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms	2012
The Biochemistry, Physiology and Pathological roles of PAI-1 and the requirements for PAI-1 inhibition in vivo BV de Craen, PJ Declerck, A Gils	Thrombosis Research	2012
Fibrinolytic system in preeclampsia MB Pinheiro, KB Gomes, LM Dusse	Clinica Chimica Acta	2012
Low Molecular Weight Antagonists of Plasminogen Activator Inhibitor-1: Therapeutic Potential in Cardiovascular Disease TM Simone, PJ Higgins		2012
The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesicles Q Jiang, NA Gingles, MA Olivier, LA Miles, RJ Parmer	Blood	2011
Advances in Cancer Research M Lemaire, S Deleu, ED Bruyne, EV Valckenborgh, E Menu, K Vanderkerken	Advances in Cancer Research Volume 110	2011
Relations du système plasminogène-plasmine et cancer PM Martin, C Dussert, S Romain, LH Ouafik	Oncologie	2010
The ovine plasminogen activator inhibitors type 1 and type 2 cDNAs: Molecular cloning, characterization and expression in various tissues G Theodorou, I Bizelis, E Rogdakis, I Politis	Gene	2010
Plasminogen activator inhibitor 1 gene polymorphisms and mirtazapine responses in Koreans with major depression HS Chang, HY Lee, BJ Ham, RH Kang, YJ Jeong, HM Kim, SW Hahn, MS Lee	ASIA-PAC PSYCHIAT	2009
Role of Tissue-Type Plasminogen Activator in Salicylic Acid–Induced Sloughing of Human Corn Tissue GD Heda, LK Roberts	J AM PODIAT MED ASSN	2008
Hydroxyapatite formed on/in agarose gel induces activation of blood coagulation and platelets aggregation S Arimura, K Kawahara, KK Biswas, K Abeyama, M Tabata, T Shimoda, D Ogomi, M Matsusaki, S Kato, T Ito, K Sugihara, M Akashi, T Hashiguchi, I Maruyama	Journal of Biomedical Materials Research Part B: Applied Biomaterials	2007
Differential Release of Plasminogen Activator Inhibitors (PAIs) During Dual Perfusion of Human Placenta: Implications in Preeclampsia S Guller, Y Ma, A Malek, SD Santo, H Schneider	Placenta	2007
Expression of plasminogen activator inhibitors type 1 and type 3 and urokinase plasminogen activator protein and mRNA in breast cancer R Castelló, JM Landete, F España, C Vázquez, C Fuster, SM Almenar, LA Ramón, KP Radtke, A Estellés	Thrombosis Research	2007
Post-Genomic Cardiology J Marín-García, MJ Goldenthal, GW Moe	Post-Genomic Cardiology	2007
Design and screening of antisense oligodeoxynucleotides against PAI-1 mRNA in endothelial cells in vitro1 Q JIANG, S WANG	Acta Pharmacologica Sinica	2006
Plasminogen activator inhibitor-1 4G/5G polymorphism in breast cancer patients and its association with tissue PAI-1 levels and tumor severity R Castelló, F España, C Vázquez, C Fuster, SM Almenar, J Aznar, A Estellés	Thrombosis Research	2006
ERK contributes to the effects of Smad signaling on oxidized LDL-induced PAI-1 expression in human mesangial cells HK Hong, CY Song, BC Kim, HS Lee	Translational Research	2006
Pivotal role of plasminogen-activator inhibitor 1 in vascular disease M Agirbasli	International Journal of Clinical Practice	2005
Iron-mediated stability of PAI-1 mRNA in adenocarcinoma cells—involvement of a mRNA-binding nuclear protein KS Radha, M Sugiki, E Yoshida, MH Kumar, S Omura, M Maruyama	Thrombosis Research	2005
Protein and mRNA expression of uPAR and PAI-1 in myoepithelial cells of early breast cancer lesions and normal breast tissue R Hildenbrand, N Arens	British Journal of Cancer	2004
Preservation of the Characteristics of the Cultured Human Type II Alveolar Epithelial Cells K Takahashi, M Mitsui, K Takeuchi, Y Uwabe, K Kobayashi, Y Sawasaki, T Matsuoka	Lung	2004
Plasminogen activator inhibitor 1 (PAI-1): in vitro activities and clinical relevance AJ Horrevoets	British Journal of Haematology	2004
Inhibition of plasminogen activator inhibitor-1: antibody fragments and their unique sequences as a tool for the development of profibrinolytic drugs K Verbeke, A Gils, PJ Declerck	Journal of Thrombosis and Haemostasis	2004
Comparative analysis of the proteinase specificity in wild-type and stabilized plasminogen activator inhibitor-1: evidence for contribution of intramolecular flexibility BD Taeye, A Gils, N Vleugels, A Rabijns, PJ Declerck	Biochemical and Biophysical Research Communications	2004
19 F NMR Studies of Plasminogen Activator Inhibitor-1 GL Abbott, GE Blouse, MJ Perron, JD Shore, LA Luck, AG Szabo	Biochemistry	2004
Expression profiles of fibrinolytic components in nasal mucosa T Sejima, S Madoiwa, J Mimuro, T Sugo, T Ishida, K Ichimura, Y Sakata	Histochemistry and Cell Biology	2004
Distal hinge of plasminogen activator inhibitor-1 involves its latency transition and specificities toward serine proteases Q Wang, S Shaltiel	BMC Biochemistry	2003
Tryptophan properties in fluorescence and functional stability of plasminogen activator inhibitor 1 S Verheyden, A Sillen, A Gils, PJ Declerck, Y Engelborghs	Biophysical Journal	2003
Astrocyte regulation of human brain capillary endothelial fibrinolysis JA Kim, ND Tran, SJ Wang, MJ Fisher	Thrombosis Research	2003
Tryptophan Properties in Fluorescence and Functional Stability of Plasminogen Activator Inhibitor 1 S Verheyden, A Sillen, A Gils, PJ Declerck, Y Engelborghs	Biophysical Journal	2003
Structural determinants in the stability of the serpin/proteinase complex BD Taeye, K Verbeke, G Compernolle, W Biesemans, A Gils, PJ Declerck	Biochemical and Biophysical Research Communications	2003
Constitutive Activation of rac 1 Results in Mitochondrial Oxidative Stress and Induces Premature Endothelial Cell Senescence SS Deshpande, B Qi, YC Park, K Irani	Arteriosclerosis, thrombosis, and vascular biology	2003
Plasminogen: Structure, Activation, and Regulation DM Waisman		2003
Post-Transcriptional Regulation of Gene Expression in the Plasminogen Activation System N Montuori, G Rossi, P Ragno	Biological Chemistry	2002
Expression of glomerular plasminogen activator inhibitor type 1 in glomerulonephritis K Hamano, M Iwano, Y Akai, H Sato, A Kubo, Y Nishitani, H Uyama, Y Yoshida, M Miyazaki, H Shiiki, S Kohno, K Dohi	American Journal of Kidney Diseases	2002
The active fraction of plasmatic plasminogen activator inhibitor type 1 as a possible indicator of increased risk for metastatic melanoma GS Hanekom, HM Stubbings, SH Kidson	Cancer Detection and Prevention	2002
Differential regulation of TGF-β signal in hepatic stellate cells between acute and chronic rat liver injury Y Tahashi	Hepatology	2002
Increased expression of the Zn-finger transcription factor BTEB1 in human endometrial cells is correlated with distinct cell phenotype, gene expression patterns, and proliferative responsiveness to serum and TGF-β1 XL Zhang, FA Simmen, FJ Michel, RC Simmen	Molecular and Cellular Endocrinology	2001
Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression FW Frueh, KC Hayashibara, PO Brown, JP Whitlock	Toxicology Letters	2001
Transforming growth factor beta-1 stimulates invasivity of hepatic stellate cells by engagement of the cell-associated fibrinolytic system G Fibbi, M Pucci, S D'Alessio, C Grappone, G Pellegrini, R Salzano, A Casini, S Milani, MD Rosso	Growth Factors	2001
The Distal Hinge of the Reactive Site Loop and Its Proximity: A TARGET TO MODULATE PLASMINOGEN ACTIVATOR INHIBITOR-1 ACTIVITY AP Bijnens, A Gils, JM Stassen, AA Komissarov, I Knockaert, E Brouwers, JD Shore, PJ Declerck	The Journal of biological chemistry	2001
Recombinant Semliki Forest virus enhanced plasminogen activator inhibitor 1 expression and storage in the megakaryocytic cell line MEG-01 JL Chuang, RR Schleef	Journal of Cellular Biochemistry	2001
Human L1 Retrotransposition: cisPreference versus trans Complementation W Wei, N Gilbert, SL Ooi, JF Lawler, EM Ostertag, HH Kazazian, JD Boeke, JV Moran	Molecular and cellular biology	2001
Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26 WS Chang, NT Chang, SC Lin, CW Wu, FY Wu	Genes, Chromosomes and Cancer	2000
Induction of endometrial plasminogen activator–inhibitor 1: a possible mechanism contributing to the effect of intrauterine levonorgestrel in the treatment of menorrhagia EM Rutanen, R Hurskainen, P Finne, K Nokelainen	Fertility and Sterility	2000
Regulation of plasminogen activation by TGF-beta in cultured human retinal endothelial cells SM Wileman, NA Booth, N Moore, B Redmill, JV Forrester, RM Knott	The British journal of ophthalmology	2000
Post-transcriptional regulation of endothelial cell plasminogen activator inhibitor-1 expression during R. rickettsii infection RJ Shi, PJ Simpson-Haidaris, VJ Marder, DJ Silverman, LA Sporn	Microbial Pathogenesis	2000
Emerging regulatory mechanisms for fibrinolytic gene expression M Koziczak, L Montero, F Maurer, Y Nagamine	Fibrinolysis and Proteolysis	2000
Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation H Nar, M Bauer, JM Stassen, D Lang, A Gils, PJ Declerck	Journal of Molecular Biology	2000
PAI-1 stability: the role of histidine residues H Mångs, GC Sui, B Wiman	FEBS Letters	2000
Vitronectin deficiency is associated with increased wound fibrinolysis and decreased microvascular angiogenesis in mice YC Jang, R Tsou, NS Gibran, FF Isik	Surgery	2000
Apical and non-polarized secretion of serpins from MDCK cells LK Vogel, JE Larsen	FEBS Letters	2000
Modulation of Endogenous Smad Expression in Normal Skin Fibroblasts by Transforming Growth Factor-β Y Mori, SJ Chen, J Varga	Experimental Cell Research	2000
Inactivation of Plasminogen Activator Inhibitor-1 by Specific Proteolysis with Stromelysin-1 (MMP-3) HR Lijnen, B Arza, BV Hoef, D Collen, PJ Declerck	The Journal of biological chemistry	2000
Mechanical stress enhances expression and production of plasminogen activator in aging human periodontal ligament cells S Miura, M Yamaguchi, N Shimizu, Y Abiko	Mechanisms of Ageing and Development	2000
Importance of the Hinge Region between α-Helix F and the Main Part of Serpins, Based upon Identification of the Epitope of Plasminogen Activator Inhibitor Type 1 Neutralizing Antibodies AP Bijnens, A Gils, I Knockaert, JM Stassen, PJ Declerck	The Journal of biological chemistry	2000
Structures of Active and Latent PAI-1: A Possible Stabilizing Role for Chloride Ions TJ Stout, H Graham, DI Buckley, DJ Matthews	Biochemistry	2000
Antisense Oligonucleotide of Tissue Inhibitor of Metalloproteinase-1 Induces the Plasminogen Activator Activity in Periodontal Ligament Cells Y Shibata, H Takiguchi, Y Abiko	Journal of Periodontology	1999
Urokinase gene expression indicates early invasive growth in squamous cell lesions of the uterine cervix L Riethdorf, S Riethdorf, S Petersen, M Bauer, H Herbst, F J�nicke, T L�ning	The Journal of Pathology	1999
Engineering of conformations of plasminogen activator inhibitor-1. A crucial role of beta-strand 5A residues in the transition of active form to latent and substrate forms T Kirkegaard, S Jensen, SL Schousboe, HH Petersen, R Egelund, PA Andreasen, KW Rodenburg	European Journal of Biochemistry	1999
Evidence that Heparin but Not Hirudin Reduces PAI-1 Expression in Cultured Human Endothelial Cells J Orbe, R Montes, N Zabalegui, A Pérez-Ruiz, JA Páramo	Thrombosis Research	1999
Functions of the fibrinolytic system in human Ito cells and its control by basic fibroblast and platelet-derived growth factor G Fibbi, M Pucci, C Grappone, G Pellegrini, R Salzano, A Casini, S Milani, MD Rosso	Hepatology	1999
Induction of conformational changes within crystals of plasminogen activator inhibitor-1 (PAI-1) PK Willems, A Gils, K Aertgeerts, CJ Ranter, PJ Declerck	Fibrinolysis and Proteolysis	1999
Management of Acute Coronary Syndromes CP Cannon		1999
Enhancement of LPS-stimulated plasminogen activator production in aged gingival fibroblasts K Mochizuki, M Yamaguchi, Y Abiko	Journal of Periodontal Research	1999
Endothelial cell activation PB Bal	Kidney International	1998
Effect of Aging on Functional Changes of Periodontal Tissue Cells Y Abiko, N Shimizu, M Yamaguchi, H Suzuki, H Takiguchi	Annals of Periodontology	1998
Cloning and high-level expression of plasminogen activator inhibitor-1 cDNA derived from human glomerular mesangial cells Y Deng, X Chen, H Liao, Y Ye, Q Xu, L Yu	Science in China Series C: Life Sciences	1998
Functional effects of single amino acid substitutions in the region of Phe113 to Asp138 in the plasminogen activator inhibitor 1 molecule GC Sui, B Wiman	Biochemical Journal	1998
Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors alpha2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves basic residues in the inhibitor KW Rodenburg, L Kjoller, HH Petersen, PA Andreasen	Biochemical Journal	1998
Stability of plasminogen activator inhibitor-1: role of tyrosine221 GC Sui, B Wiman	FEBS Letters	1998
Stimulatory effect of interleukin-6 on plasminogen activator activity from human dental pulp cells S Hosoya, E Ohbayashi, K Matsushima, H Takeuchi, M Yamazaki, Y Shibata, Y Abiko	Journal of Endodontics	1998
Characterization of plasminogen activator inhibitor 1 mutants containing the P13 to P10 region of ovalbumin or antithrombin III: evidence that the P13 residue contributes significantly to the active to substrate transition A Gils, N Vleugels, K Tobback, I Knockaert, PJ Declerck	Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology	1998
Thromboxane A 2 modulates the fibrinolytic system in glomerular mesangial cells TM Coffman, RF Spurney, RB Mannon, R Levenson	American journal of physiology. Renal physiology	1998
Cyclic Nucleotide Regulation of Type-1 Plasminogen Activator-Inhibitor mRNA Stability in Rat Hepatoma Cells: IDENTIFICATION OF cis -ACTING SEQUENCES JH Heaton, M Tillmann-Bogush, NS Leff, TD Gelehrter	The Journal of biological chemistry	1998
The Structure and Function of Murine Factor V and Its Inactivation by Protein C TL Yang, J Cui, A Rehumtulla, A Yang, M Moussalli, RJ Kaufman, D Ginsburg	Blood	1998
Atherosclerosis EM MD, ST MD, EA MD, AW MD, ED MD	The Annals of Thoracic Surgery	1997
Low-energy diode laser irradiation reduced plasminogen activator activity in human periodontal ligament cells Y Ozawa, N Shimizu, Y Abiko	Lasers in Surgery and Medicine	1997
Cholesterol feeding accentuates the cyclosporine-induced elevation of renal plasminogen activator inhibitor type 1 C Duymelinck, SE Dauwe, EJ Nouwen, ME de Broe, GA Verpooten	Kidney International	1997
TGF-β and the endothelium during immune injury P Pintavorn, BJ Ballermann	Kidney International	1997
Rational Design of Complex Formation between Plasminogen Activator Inhibitor-1 and Its Target Proteinases K Aertgeerts, CJ de Ranter, NA Booth, PJ Declerck	Journal of Structural Biology	1997
Advances in Molecular and Cell Biology KJ Clemetson	Advances in Molecular and Cell Biology	1997
Construction and characterization of plasminogen activator inhibitor-1 mutants in which part of the active site loop is deleted A Gils, I Knockaert, PJ Declerck	Fibrinolysis and Proteolysis	1997
Epitopes on plasminogen activator inhibitor type-1 important for binding to tissue plasminogen activator P Björquist, J Ehnebom, T Inghardt, J Deinum	Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology	1997
Proteinase Specificity and Functional Diversity in Point Mutants of Plasminogen Activator Inhibitor 1 A Gils, PJ Declerck	The Journal of biological chemistry	1997
Cloning of a single-chain variable fragment (scFv) switching active plasminogen activator inhibitor-1 to substrate S Debrock, L Sironi, PJ Declerck	Gene	1997
Purification, cDNA Cloning, and Characterization of a New Serpin with Megakaryocyte Maturation Activity M Tsujimoto, N Tsuruoka, N Ishida, T Kurihara, F Iwasa, K Yamashiro, T Rogi, S Kodama, N Katsuragi, M Adachi, T Katayama, M Nakao, K Yamaichi, J Hashino, M Haruyama, K Miura, T Nakanishi, H Nakazato, M Teramura, H Mizoguchi, N Yamaguchi	The Journal of biological chemistry	1997
Neutralization of plasminogen activator inhibitor-1 inhibitory properties: identification of two different mechanisms S Debrock, PJ Declerck	Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology	1997
Intracellular Calcium Mobilization Suppresses the TNF-α–Stimulated Synthesis of PAI-1 in Human Endothelial Cells: Indications That Calcium Acts at a Translational Level F Peiretti, MC Alessi, M Henry, F Anfosso, I Juhan-Vague, G Nalbone	Arteriosclerosis, thrombosis, and vascular biology	1997
Five Frequent Polymorphisms of the PAI-1 Gene: Lack of Association Between Genotypes, PAI Activity, and Triglyceride Levels in a Healthy Population M Henry, N Chomiki, PY Scarabin, MC Alessi, F Peiretti, D Arveiler, J Ferrières, A Evans, P Amouyel, O Poirier, F Cambien, I Juhan-Vague	Arteriosclerosis, thrombosis, and vascular biology	1997
Plasminogen Activator Inhibitor-1 in Neointima of Vein Grafts: Its Role in Reduced Fibrinolytic Potential and Graft Failure P Kauhanen, V Sirén, O Carpén, A Vaheri, M Lepäntalo, R Lassila	Circulation	1997
Plasminogen Activator Inhibitor Type 1 and Tissue Inhibitor of Metalloproteinases-2 Increase After Arterial Injury in Rats D Hasenstab, R Forough, AW Clowes	Circulation research	1997
Moderate Genetic Influences on Plasma Levels of Plasminogen Activator Inhibitor-1 and Evidence of Genetic and Environmental Influences Shared by Plasminogen Activator Inhibitor-1, Triglycerides, and Body Mass Index Y Hong, NL Pedersen, N Egberg, U de Faire	Arteriosclerosis, thrombosis, and vascular biology	1997
Textbook of Coronary Thrombosis and Thrombolysis RC Becker		1997
Effect of tension-force on plasminogen activator activity from human periodontal ligament cells M Yamaguchi, N Shimizu, Y Ozawa, K Saito, S Miura, H Takiguchi, T Iwasawa, Y Abiko	Journal of Periodontal Research	1997
The Suicide Substrate Reaction Between Plasminogen Activator Inhibitor 1 and Thrombin Is Regulated by the Cofactors Vitronectin and Heparin M van Meijer, A Smilde, G Tans, ME Nesheim, H Pannekoek, AJ Horrevoets	Blood	1997
Review M Epstein	Renal Failure	1996
Regulation of plasminogen activator inhibitor activity in endothelial cells by tissue-type plasminogen activator GY Shi, CC Hsu, BI Chang, CF Tsai, HS Han, MD Lai, MT Lin, WC Chang, LY Wing, CJ Jen, MJ Tang, HL Wu	Fibrinolysis	1996
Sex steroids regulate the expression of plasminogen activator inhibitor-1 (PAI-1) and its mRNA in uterine endometrial cancer cell line Ishikawa J Fujimoto, M Hori, S Ichigo, T Tamaya	The Journal of Steroid Biochemistry and Molecular Biology	1996
Ligand-toxin Hybrids Directed to the -Macroglobulin Receptor/Low Density Lipoprotein Receptor-related Protein Exhibit Lower Toxicity than Native Pseudomonas Exotoxin AG Zdanovsky, MV Zdanovskaia, D Strickland, DJ FitzGerald	The Journal of biological chemistry	1996
Plasminogen Activator Inhibitor Type-1 Synthesis and mRNA Expression in HepG2 Cells Are Regulated by VLDL L Sironi, L Mussoni, L Prati, D Baldassarre, M Camera, C Banfi, E Tremoli	Arteriosclerosis, thrombosis, and vascular biology	1996
Sex Steroids Regulate the Expression of Plasminogen Activator Inhibitor-1 and its mRNA in Fibroblasts Derived from Uterine Endometrium J Fujimoto, M Hori, S Ichigo, T Tamaya	Annals of Clinical Biochemistry	1996
Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1 K Aertgeerts, HL de Bondt, CJ de Ranter, PJ Declerck	Nature Structural Biology	1995
Differential growth state-dependent regulation of plasminogen activator inhibitor type-1 expression in senescent IMR-90 human diploid fibroblasts XC Mu, PJ Higgins	Journal of Cellular Physiology	1995
Crystallization and X-ray diffraction data of the cleaved form of plasminogen activator inhibitor-1 K Aertgeerts, HL de Bondt, CD Ranter, PJ Declerck	Proteins: Structure, Function, and Genetics	1995
Inhibition by Modified Oligodeoxynucleotides of the Expression of Type-1 Plasminogen Activator Inhibitor in Human Endothelial Cells CS Cierniewski, A Babinska, M Swiatkowska, M Wilczynska, A Okruszek, WJ Stec	European Journal of Biochemistry	1995
Retroviral vector–mediated transfer and expression of human tissue plasminogen activator gene in human endothelial and vascular smooth muscle cells D Ekhterae, JC Stanley	Journal of Vascular Surgery	1995
Molecular evidence that childhood monosomy 7 syndrome is distinct from juvenile chronic myelogenous leukemia and other childhood myeloproliferative disorders M Butcher, R Frenck, J Emperor, D Paderanga, D Maybee, K Olson, K Shannon	Genes, Chromosomes and Cancer	1995
Calcium oxalate monohydrate crystals stimulate gene expression in renal epithelial cells MS Hammes, JC Lieske, S Pawar, BH Spargo, FG Toback	Kidney International	1995
Plasminogen Activator Inhibitor-1 in Brain Tumors R Sawaya, M Yamamoto, OJ Rämö, ML Shi, A Rayford, JS Rao	Neurosurgery	1995
Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1 U Reuning, O Wilhelm, T Nishiguchi, L Guerrini, F Blasi, H Graeff, M Schmitt	Nucleic Acids Research	1995
Cloning of the mink plasminogen activator inhibitor type-1 messenger RNA: An mRNA with a short half life TH Chuang, RT Hamilton, M Nilsen-Hamilton	Gene	1995
Structure of plasminogen activator inhibitor 1 (PAI-1) and its function in fibrinolysis: an update M Meijer, H Pannekoek	Fibrinolysis	1995
Human hepatocytes express the gene for type 1 plasminogen activator-inhibitor (PAI-1) in vivo AJ Thornton, TD Gelehrter	Fibrinolysis	1995
Characterization of common neoantigenic epitopes generated in plasminogen activator inhibitor-1 after cleavage of the reactive center loop or after complex formation with various serine proteinases S Debrock, PJ Declerck	FEBS Letters	1995
Recombinant DNA Methodology II J Chao, KX Chai, L Chao	Recombinant DNA Methodology II	1995
Cathepsin D-like aspartyl protease activity mediates the degradation of tissue-type plasminogen activator/plasminogen activator inhibitor-1 complexes in human monocytes DI Simon, H Xu, DE Vaughan	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1995
Conformational Studies on Plasminogen Activator Inhibitor (PAI-1) in Active, Latent, Substrate, and Cleaved Forms E Sancho, PJ Declerck, NC Price, SM Kelly, NA Booth	Biochemistry	1995
Identification of Tissue-type Plasminogen Activator-specific Plasminogen Activator Inhibitor-1 Mutants: EVIDENCE THAT SECOND SITES OF INTERACTION CONTRIBUTE TO TARGET SPECIFICITY PM Sherman, DA Lawrence, IM Verhamme, D Paielli, JD Shore, D Ginsburg	The Journal of biological chemistry	1995
Plasminogen Activator Inhibitor-1 in Brain Tumors: Relation to Malignancy and Necrosis R Sawaya, M Yamamoto, OJ Rm, ML Shi, A Rayford, JS Rao	Neurosurgery	1995
Lack of Role for Nitric Oxide (NO) in the Selective Destabilization of Endothelial NO Synthase mRNA by Tumor Necrosis Factor–α F Mohamed, JC Monge, A Gordon, P Cernacek, D Blais, DJ Stewart	Arteriosclerosis, thrombosis, and vascular biology	1995
Plasminogen Activator Inhibitor 1: Molecular Aspects and Clinical Importance Vaughan	Journal of Thrombosis and Thrombolysis	1995
Influence of exogenous growth factors on the expression of plasminogen activators and plasminogen activator inhibitors by cells isolated from normal and healing rabbit ligaments PG Murphy, DA Hart	Journal of Orthopaedic Research	1994
Purification and Characterization of Active and Stable Recombinant Plasminogen-Activator Inhibitor Accumulated at High Levels in Escherichia coli E Sancho, DW Tonge, RC Hockney, NA Booth	European Journal of Biochemistry	1994
The Role of Progestationally Regulated Stromal Cell Tissue Factor and Type-1 Plasminogen Activator Inhibitor (PAI-1) in Endometrial Hemostasis and Menstruation CJ Lockwood, G Krikun, C Papp, E Toth, L Markiewicz, EY Wang, T Kerenyi, X Zhou, V Hausknecht, Z Papp, F Schatz	Annals of the New York Academy of Sciences	1994
Mechanisms of plasminogen activation HR Lijnen, F Bachmann, D Collen, V Ellis, H Pannekoek, DC Rijken, S Thorsen	Journal of Internal Medicine	1994
Vascular Endothelium MA Gimbrone, MI Cybulsky, N Kume, T Collins, N Resnick	Annals of the New York Academy of Sciences	1994
Probing structure-function relationships of tissue-type plasminogen activator by site-specific mutagenesis EL Madison	Fibrinolysis	1994
Determination of the vitronectin binding site on plasminogen activator inhibitor 1 (PAI-1) M Meijer, RK Gebbink, KT Preissner, H Pannekoek	FEBS Letters	1994
Processing of type 1 plasminogen activator inhibitor (PAI-1) into the regulated secretory pathway L Gombau, RR Schleef	The Journal of biological chemistry	1994
Induction of plasminogen activator inhibitor-1 in HepG2 human hepatoma cells by mediators of the acute phase response AM Healy, TD Gelehrter	The Journal of biological chemistry	1994
Conversion of plasminogen activator inhibitor-1 from inhibitor to substrate by point mutations in the reactive-site loop AM Audenaert, I Knockaert, D Collen, PJ Declerck	The Journal of biological chemistry	1994
Plasminogen activator inhibitor 1, the primary regulator of fibrinolysis, in normal human cerebrospinal fluid JS Rao, M Chen, BW Festoff	Journal of Neuroscience Research	1993
Contribution of sinusoidal endothelial liver cells to liver fibrosis: Expression of transforming growth factor-β1 receptors and modulation of plasmin-generating enzymes by transforming growth factor-β1 H Rieder, T Armbrust, KH Büschenfelde, G Ramadori	Hepatology	1993
Species-specific differential cleavage and polyadenylation of plasminogen activator inhibitor type 1 hnRNA PG Fattal, JJ Billadello	Nucleic Acids Research	1993
Different fibrinolytic potential in cultured human adult and umbilical vein endothelial cells V Arnman, L Rymo, B Risberg	Fibrinolysis	1993
Dynamic structural and functional relationships in recombinant plasminogen activator inhibitor-1 (rPAI-1) DE Vaughan, PJ Declerck, TM Reilly, K Park, D Collen, GD Fasman	Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology	1993
Plasminogen activators and plasminogen activator inhibitors in connective tissues and connective tissue cells: influence of the neuropeptide substance P on expression PG Murphy, DA Hart	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease	1993
Plasminogen activator inhibitor-1 mRNA is expressed in platelets and megakaryocytes and the megakaryoblastic cell line CHRF-288 BA Konkle, PK Schick, X He, RJ Liu, EM Mazur	Arteriosclerosis Thrombosis and Vascular Biology	1993
Converting Tissue Plasminogen Activator to a Zymogen: A Regulatory Triad of Asp-His-Ser EL Madison, A Kobe, MJ Gething, JF Sambrook, EJ Goldsmith	Science	1993
Isolation and characterization of an intracellular serine proteinase inhibitor from a monkey kidney epithelial cell line KA Morgenstern, WJ Henzel, JB Baker, S Wong, A Pastuszyn, W Kisiel	The Journal of biological chemistry	1993
The plasminogen-plasmin system in malignancy HC Kwaan	Cancer and Metastasis Reviews	1992
Expression of plasminogen activator and plasminogen activator inhibitor mRNA in human fibroblasts grown on different substrates J Varani, RG Sitrin, W Hillegas	Cytotechnology	1992
Complete Deficiency of Plasminogen-Activator Inhibitor Type 1 Due to a Frame-Shift Mutation WP Fay, AD Shapiro, JL Shih, RR Schleef, D Ginsburg	New England Journal of Medicine	1992
LOCALIZATION OF COMPONENTS FROM THE PLASMINOGEN ACTIVATION SYSTEM IN MAMMALIAN TISSUES P Kristensen	APMIS	1992
Purification and characterisation of recombinant rabbit plasminogen activator inhibitor-1 expressed in Saccharomyces cerevisiae KJ Hofmann, EJ Mayer, LD Schultz, SH Socher, CF Reilly	Fibrinolysis	1992
Modulation of plasminogen activator and plasminogen activator inhibitor expression in the human U373 glioblastoma/astrocytoma cell line by inflammatory mediators P Murphy, DA Hart	Experimental Cell Research	1992
Cell-specific regulation of plasminogen activator inhibitor 1 and tissue type plasminogen activator release by human kidney mesangial cells MN Peraldi, E Rondeau, RL Medcalf, J Hagège, R Lacave, D Françoise, WD Schleuning, JD Sraer	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	1992
Human HuH-7 hepatoma cells express urokinase and plasminogen activator inhibitor-1: identification, characterization and regulation by inflammatory mediators A Arndt, P Murphy, DA Hart	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease	1992
Angiogenesis in Health and Disease ME Maragoudakis, P Gullino, PI Lelkes		1992
Protein Pharmacokinetics and Metabolism BL Ferraiolo, MA Mohler, CA Gloff		1992
Saturation mutagenesis of the plasminogen activator inhibitor-1 reactive center PM Sherman, DA Lawrence, AY Yang, ET Vandenberg, D Paielli, ST Olson, JD Shore, D Ginsburg	The Journal of biological chemistry	1992
Pulmonary epithelial cell urokinase-type plasminogen activator. Induction by interleukin-1 beta and tumor necrosis factor-alpha BC Marshall, QP Xu, NV Rao, BR Brown, JR Hoidal	The Journal of biological chemistry	1992
A major estrogen-regulated protein secreted from the liver of Xenopus laevis is a member of the serpin superfamily. Nucleotide sequence of cDNA and hormonal induction of mRNA LJ Holland, C Suksang, AA Wall, LR Roberts, DR Moser, A Bhattacharya	The Journal of biological chemistry	1992
Differential Expression of Urokinase-Type Plasminogen Activator and Its Type-1 Inhibitor During Healing of Mouse Skin Wounds J Romer, LR Lund, J Eriksen, E Ralfkiaer, R Zeheb, TD Gelehrter, K Dano, P Kristensen	Journal of Investigative Dermatology	1991
Tumor necrosis factor and epidermal growth factor modulate migration of human microvascular endothelial cells and production of tissue-type plasminogen activator and its inhibitor M Mawatari, K Okamura, T Matsuda, R Hamanaka, H Mizoguchi, K Higashio, K Kohno, M Kuwano	Experimental Cell Research	1991
Cartilage synthesizes the serine protease inhibitor PAI-1: Support for the involvement of serine proteases in cartilage remodeling BV Treadwell, M Pavia, CA Towle, VJ Cooley, HJ Mankin	Journal of Orthopaedic Research	1991
Thrombin neutralizes plasminogen activator inhibitor 1 (PAI-1) that is complexed with vitronectin in the endothelial cell matrix HJ Ehrlich, RK Gebbink, KT Preissner, J Keijer, NL Esmon, K Mertens, H Pannekoek	The Journal of Cell Biology	1991
The 29-kDa proteins phosphorylated in thrombin-activated human platelets are forms of the estrogen receptor-related 27-kDa heat shock protein ME Mendelsohn, Y Zhu, S O'Neill	Proceedings of the National Academy of Sciences	1991
Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence S Murano, R Thweatt, RJ Reis, RA Jones, EJ Moerman, S Goldstein	Molecular and cellular biology	1991
Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence C Hassett, RJ Richter, R Humbert, C Chapline, JW Crabb, CJ Omiecinski, CE Furlong	Biochemistry	1991
Synthesis and secretion of plasminogen activator inhibitor 1 by human endothelial cells in vitro. Effect of active site mutagenized tissue-type plasminogen activator K Bartha, PJ Declerck, H Moreau, L Nelles, D Collen	The Journal of biological chemistry	1991
Combinatorial mutagenesis of the reactive site region in plasminogen activator inhibitor I JD York, P Li, SJ Gardell	The Journal of biological chemistry	1991
Vitronectin governs the interaction between plasminogen activator inhibitor 1 and tissue-type plasminogen activator J Keijer, HJ Ehrlich, M Linders, KT Preissner, H Pannekoek	The Journal of biological chemistry	1991
Different induction of two plasminogen activator inhibitor 1 mRNA species by phorbol ester in human hepatoma cells PJ Bosma, T Kooistra	The Journal of biological chemistry	1991
Plasminogen activator inhibitors: hormonally regulated serpins PA Andreasen, B Georg, LR Lund, A Riccio, SN Stacey	Molecular and Cellular Endocrinology	1990
Transforming Growth Factor-? in Psoriasis: Pathogenesis and Therapy JT Elder, LR Ellingsworth, GJ Fisher, JJ Voorhees	Annals of the New York Academy of Sciences	1990
Transforming Growth Factor-beta Modulates Plasminogen Activator Activity and Plasminogen Activator Inhibitor Type-1 Expression in Human Keratinocytes In Vitro NE Wikner, JT Elder, KA Persichitte, P Mink, RA Clark	Journal of Investigative Dermatology	1990
Forskolin down-regulates type-1 plasminogen activator inhibitor and tissue-type plasminogen activator and their mRNAs in human fibrosarcoma cells B Georg, A Riccio, P Andreasen	Molecular and Cellular Endocrinology	1990
Modulation of levels of messenger RNA for tissue-type plasminogen activator in rat Sertoli cells, and levels of messenger RNA for plasminogen activator inhibitor in testis peritubular cells C Nargolwalla, D McCabe, IB Fritz	Molecular and Cellular Endocrinology	1990
The Fibrinolytic System of the Vessel Wall and Its Role in the Control of Thrombosis DJ Loskutoff, SA Curriden	Annals of the New York Academy of Sciences	1990
Conformational differences between latent and active plasminogen activator inhibitor, PAI-1: A spectroscopic study S Boström, J Deinum, JE Löfroth, M Wirth, M Kubista	Thrombosis Research	1990
Stabilisation of plasminogen activator inhibitor type 1 (PAI-1) activity by arginine: Possible implications for the interaction of PAI-1 with vitronectin J Keijer, M Linders, H Ehrlich, RK Gebbink, H Pannekoek	Fibrinolysis	1990
Expression of human plasminogen activator inhibitor type-1 (PAI-1) in Escherichia coli as a soluble protein comprised of active and latent forms. Isolation and crystallization of latent PAI-1 AE Franke, DE Danley, FS Kaczmarek, SJ Hawrylik, RD Gerard, SE Lee, KF Geoghegan	Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology	1990
Studies of recombinant plasminogen activator inhibitor-1 in rabbits. Pharmacokinetics and evidence for reactivation of latent plasminogen activator inhibitor-1 in vivo DE Vaughan, PJ Declerck, EV Houtte, MD Mol, D Collen	Circulation research	1990
Cytokine-enhanced expression of glycoprotein Ib alpha in human endothelium BA Konkle, SS Shapiro, AS Asch, RL Nachman	The Journal of biological chemistry	1990
Alteration of serpin specificity by a protein cofactor. Vitronectin endows plasminogen activator inhibitor 1 with thrombin inhibitory properties HJ Ehrlich, RK Gebbink, J Keijer, M Linders, KT Preissner, H Pannekoek	The Journal of biological chemistry	1990
Heparin-binding growth factor-1 modulation of plasminogen activator inhibitor-1 expression. Interaction with cAMP and protein kinase C-mediated pathways BA Konkle, PR Kollros, MD Kelly	The Journal of biological chemistry	1990
Isolation and characterization of the rat plasminogen activator inhibitor-1 gene CJ Bruzdzinski, M Riordan-Johnson, EC Nordby, SM Suter, TD Gelehrter	The Journal of biological chemistry	1990
Purification and characterization of recombinant plasminogen activator inhibitor-1 from Escherichia coli TM Reilly, R Seetharam, JL Duke, GL Davis, SK Pierce, HL Walton, D Kingsley, WP Sisk	The Journal of biological chemistry	1990
Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma P Kristensen, C Pyke, LR Lund, PA Andreasen, K Dan	Histochemistry	1990
Bleeding diathesis due to decreased functional activity of type 1 plasminogen activator inhibitor RR Schleef, DL Higgins, E Pillemer, LJ Levitt	Journal of Clinical Investigation	1989
A monoclonal antibody to von Willebrand factor (vWF) inhibits factor VIII binding. Localization of its antigenic determinant to a nonadecapeptide at the amino terminus of the mature vWF polypeptide WF Bahou, D Ginsburg, R Sikkink, R Litwiller, DN Fass	Journal of Clinical Investigation	1989
Recombinant plasminogen activator inhibitor-1 reverses the bleeding tendency associated with the combined administration of tissue-type plasminogen activator and aspirin in rabbits DE Vaughan, PJ Declerck, MD Mol, D Collen	Journal of Clinical Investigation	1989
Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger an OF Wagner, C Vries, C Hohmann, H Veerman, H Pannekoek	Journal of Clinical Investigation	1989
Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7 KM Shannon, AG Turhan, SS Chang, AM Bowcock, PC Rogers, WL Carroll, MJ Cowan, BE Glader, CJ Eaves, AC Eaves	Journal of Clinical Investigation	1989
Tumor necrosis factor-α regulates mRNA for urokinase-type plasminogen activator and type-1 plasminogen activator inhibitor in human neoplastic cell lines B Georg, E Helseth, LR Lund, T Skandsen, A Riccio, K Dane, G Unsgaard, PA Andreasen	Molecular and Cellular Endocrinology	1989
Determination of Exon–Intron Structure: A Novel Application of the Polymerase Chain Reaction Technique CJ Bruzdzinski, TD Gelehrter	DNA	1989
Purification of active human plasminogen activator inhibitor 1 from Escherichia coli. Comparison with natural and recombinant forms purified from eucaryotic cells D LAWRENCE, L STRANDBERG, T GRUNDSTROM, T NY	European Journal of Biochemistry	1989
Characterization of Keratinocyte Plasminogen Activator Inhibitors and Demonstration of the Prevention of Pemphigus IgG-induced Acantholysis by a Purified Plasminogen Activator Inhibitor K Hashimoto, TC Wun, J Baird, GS Lazarus, PJ Jensen	Journal of Investigative Dermatology	1989
Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils E Remold-O'Donnell, JC Nixon, RM Rose	Journal of Experimental Medicine	1989
Plasminogen activator inhibitor-type I is a major biosynthetic product of retinal microvascular endothelial cells and pericytes in culture AE Canfield, AM Schor, DJ Loskutoff, SL Schor, ME Grant	Biochemical Journal	1989
RFLP for Sst I (Sac I) at the human plasminogen activator inhibitor type 1 (PAI-1) gene locus I Kondo, K Berg	Nucleic Acids Research	1989
Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor MV Cubellis, P Andreasen, P Ragno, M Mayer, K Danø, F Blasi	Proceedings of the National Academy of Sciences	1989
Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma Y Ke, RR Reddel, BI Gerwin, HK Reddel, AN Somers, MG McMenamin, MA LaVeck, RA Stahel, JF Lechner, CC Harris	The American Journal of Pathology	1989
Structure and expression of the human gene encoding plasminogen activator inhibitor, PAI-1 M Follo, D Ginsburg	Gene	1989
Plasminogen activator inhibitor type 2 cDNA transfected into Chinese hamster ovary cells is stably expressed but not secreted T Ny, L Hansson, D Lawrence, G Leonardsson, B Åstedt	Fibrinolysis	1989
The role of ovarian proteases and their inhibitors in ovulation TE Curry, DD Dean, SL Sanders, NG Pedigo, PB Jones	Steroids	1989
Sodium-N-butyrate induces secretion and substrate accumulation of p52 in kirsten sarcoma virus-transformed rat kidney fibroblasts MP Ryan, PJ Higgins	International Journal of Biochemistry	1989
Serpin-resistant mutants of human tissue-type plasminogen activator EL Madison, EJ Goldsmith, RD Gerard, MJ Gething, JF Sambrook	Nature	1989
Plasminogen activator inhibitor (type-1) in rat adrenal medulla J Eriksen, P Kristensen, C Pyke, K Dan	Histochemistry	1989
CpG Mutations in the Reactive Site of Human C 1¯ Inhibitor K Skriver, E Radziejewska, JA Silbermann, VH Donaldson, SC Bock	The Journal of biological chemistry	1989
Regulation of Type 1 Plasminogen Activator Inhibitor Gene Expression in Cultured Bovine Aortic Endothelial Cells M Sawdey, TJ Podor, DJ Loskutoff	The Journal of biological chemistry	1989
Regulation of endothelial cell coagulant properties EM Scarpati, JE Sadler	The Journal of biological chemistry	1989
Affinity purification of active plasminogen activator inhibitor-1 (PAI-1) using immobilized anhydrourokinase TC Wun, MO Palmier, NR Siegel, CE Smith	The Journal of biological chemistry	1989
Structure of the Gene for Human Plasminogen Activator Inhibitor-2 RD Ye, SM Ahern, MM Beau, RV Lebo, JE Sadler	The Journal of biological chemistry	1989
Variability in messenger RNA levels in human umbilical vein endothelial cells of different lineage and time in culture D Dichek, T Quertermous	In Vitro Cellular & Developmental Biology – Animal	1989
The addition of endothelial cell growth factor and heparin to human umbilical vein endothelial cell cultures decreases plasminogen activator inhibitor-1 expression BA Konkle, D Ginsburg	Journal of Clinical Investigation	1988
Plasminogen activator inhibitor type 1: cell-specific and differentiation-induced expression and regulation in human cell lines, as determined by enzyme-linked immunosorbent assay LR Lund, B Georg, LS Nielsen, M Mayer, K Danø, PA Andreasen	Molecular and Cellular Endocrinology	1988
Urokinase- and Tissue-Type Plasminogen Activators in Keratinocytes During Wound Reepithelialization In Vivo J Grondahl-Hansen, LR Lund, E Ralfkiaer, V Ottevanger, K Dano	Journal of Investigative Dermatology	1988
Kinetics of inhibition of tissue-type and urokinase-type plasminogen activator by plasminogen-activator inhibitor type 1 and type 2 S THORSEN, M PHILIPS, J SELMER, I LECANDER, B ASTEDT	European Journal of Biochemistry	1988
Purification and characterization of natural and recombinant human plasminogen activator inhibitor-1 (PAI-1) MC ALESSI, PJ DECLERCK, M MOL, L NELLES, D COLLEN	European Journal of Biochemistry	1988
The organization of the human-plasminogen-activator-inhibitor-1 gene. Implications on the evolution of the serine-protease inhibitor family L STRANDBERG, D LAWRENCE, T NY	European Journal of Biochemistry	1988
Bovine endothelial cell plasminogen activator inhibitor. Purification and heat activation K KATAGIRI, K OKADA, H HATTORI, M YANO	European Journal of Biochemistry	1988
Transforming growth factor-β1 is a potent inducer of plasminogen activator inhibitor type-1 in human glioblastoma and carcinoma cell lines E Helseth, A Dalen, G Unsgaard, T Skandsen, J GrØNdahl-Hansen, LR Lund	APMIS	1988
Cloning and expression of a cDNA coding for a human monocyte-derived plasminogen activator inhibitor TM Antalis, MA Clark, T Barnes, PR Lehrbach, PL Devine, G Schevzov, NH Goss, RW Stephens, P Tolstoshev	Proceedings of the National Academy of Sciences	1988
The regulatory region of the human plasminogen activator inhibitor type-1 (PAI-1) gene A Riccio, LR Lund, R Sartorio, A Lania, PA Andreasen, K Danø, F Blasi	Nucleic Acids Research	1988
Cloning and sequencing of cDNA for the rat plasminogen activator inhibitor-1 R Zeheb, TD Gelehrter	Gene	1988
Surface receptors for urokinase plasminogen activator F Blasi	Fibrinolysis	1988
Plasminogen activators and their inhibitors: regulators of extracellular proteolysis and cell function DA Hart, A Rehemtulla	Comparative Biochemistry and Physiology Part B: Comparative Biochemistry	1988
Immunohistochemical localization of urokinase-type plasminogen activator in sertoli cells and tissue-type plasminogen activator in spermatogenic cells in the rat seminiferous epithelium KK Vihko, P Kristensen, K Danø, M Parvinen	Developmental Biology	1988
International Review of Experimental Pathology P Hoedemaeker	International Review of Experimental Pathology	1988
Mutants of human tissue-type plasminogen activator (t-PA): Structural aspects and functional properties H Pannekoek, C Vries, AJ Zonneveld	Fibrinolysis	1988
Purification and characterization of placental protein 5 R Bützow, ML Huhtala, H Bohn, I Virtanen, M Seppälä	Biochemical and Biophysical Research Communications	1988
Artificial exon shuffling between tissue-type plasminogen activator (t-PA) and urokinase (u-PA): a comparative study on the fibrinolytic properties of t-PA/u-PA hybrid proteins CD Vries, H Veerman, F Blasi, H Pannekoek	Biochemistry	1988
Bovine plasminogen activator inhibitor 1: Specificity determinations and comparison of the active, latent, and guanidine-activated forms CM Hekman, DJ Loskutoff	Biochemistry	1988
Genetic markers on chromosome 7 LC Tsui	Journal of medical genetics	1988
Human plasminogen activator inhibitor-1 gene. Promoter and structural gene nucleotide sequences PJ Bosma, EA van den Berg, T Kooistra, DR Siemieniak, JL Slightom	The Journal of biological chemistry	1988
Regulation of the expression of type 1 plasminogen activator inhibitor in Hep G2 cells by epidermal growth factor CL Lucore, S Fujii, TC Wun, BE Sobel, JJ Billadello	The Journal of biological chemistry	1988
Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor RR Schleef, MP Bevilacqua, M Sawdey, MA Gimbrone, DJ Loskutoff	The Journal of biological chemistry	1988
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells J Keski-Oja, R Raghow, M Sawdey, DJ Loskutoff, AE Postlethwaite, AH Kang, HL Moses	The Journal of biological chemistry	1988
Plasminogen activator inhibitor type-1 protein, mRNA and gene transcription are increased by phorbol esters in human rhabdomyosarcoma cells M Mayer, LR Lund, A Riccio, J Skouv, LS Nielsen, SN Stacey, K Danø, PA Andreasen	The Journal of biological chemistry	1988
Human monocyte Arg-Serpin cDNA. Sequence, chromosomal assignment, and homology to plasminogen activator-inhibitor AC Webb, KL Collins, SE Snyder, SJ Alexander, LJ Rosenwasser, RL Eddy, TB Shows, PE Auron	Journal of Experimental Medicine	1987
Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors F Blasi, JD Vassalli, K Danø	The Journal of Cell Biology	1987
Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors GL Hammond, CL Smith, IS Goping, DA Underhill, MJ Harley, J Reventos, NA Musto, GL Gunsalus, CW Bardin	Proceedings of the National Academy of Sciences	1987
Plasminogen activator inhibitor type 1 biosynthesis and mRNA level are increased by dexamethasone in human fibrosarcoma cells PA Andreasen, C Pyke, A Riccio, P Kristensen, LS Nielsen, LR Lund, F Blasi, K Danø	Molecular and cellular biology	1987
Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts LR Lund, A Riccio, PA Andreasen, LS Nielsen, P Kristensen, M Laiho, O Saksela, F Blasi, K Danø	The EMBO Journal	1987
Plasminogen activator inhibitor type 1 gene is located at region q21.3-q22 of chromosome 7 and genetically linked with cystic fibrosis KW Klinger, R Winqvist, A Riccio, PA Andreasen, R Sartorio, LS Nielsen, N Stuart, P Stanislovitis, P Watkins, R Douglas	Proceedings of the National Academy of Sciences	1987
Endotoxin-induced secretion of an active plasminogen activator inhibitor from bovine pulmonary arterial and aortic endothelial cells DJ Crutchley, LB Conanan, US Ryan	Biochemical and Biophysical Research Communications	1987
Structure of the human plasminogen activator inhibitor 1 gene: nonrandom distribution of introns DJ Loskutoff, M Linders, J Keijer, H Veerman, HV Heerikhuizen, H Pannekoek	Biochemistry	1987
Activation of human endothelial cell-type plasminogen activator inhibitor (PAI-1) by negatively charged phospholipids JW Lambers, M Cammenga, BW König, K Mertens, H Pannekoek, JA van Mourik	The Journal of biological chemistry	1987
cDNA cloning and expression in Escherichia coli of a plasminogen activator inhibitor from human placenta RD Ye, TC Wun, JE Sadler	The Journal of biological chemistry	1987
Clinical Chemistry RM Archibald	Analytical Chemistry	1953

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