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Citations to this article

T cells and probably B cells arise from the malignant clone in chronic myelogenous leukemia.
A A Fauser, … , K J Bross, G W Löhr
A A Fauser, … , K J Bross, G W Löhr
Published March 1, 1985
Citation Information: J Clin Invest. 1985;75(3):1080-1082. https://doi.org/10.1172/JCI111771.
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Research Article

T cells and probably B cells arise from the malignant clone in chronic myelogenous leukemia.

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Abstract

Bone marrow cells from a patient with Ph' positive chronic myelogenous leukemia in chronic phase were cultured for multilineage hematopoietic colonies (CFU-GEMMT), erythroid bursts, and granulocytic colonies. With CFU-GEMMT colonies, T lymphocytes were identified by reaction with monoclonal antibodies Leu-5 and OKT-3; B cells were identified by reaction with B1. All CFU-GEMMT colonies examined contained the Ph' chromosome. Recloned secondary colonies of T cells reacted with Leu-5 and OKT-3 and were Ph' positive. This demonstrates that Ph' positive T lymphocytes were generated from the pluripotential stem cell of this patient. The presence of B cells in the mixed colonies indicates that these may also be derived from the neoplastic clone.

Authors

A A Fauser, L Kanz, K J Bross, G W Löhr

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Total citations by year

Year: 2013 2011 2009 2007 2000 1998 1997 1995 1994 1993 1991 1990 1989 1988 1987 1986 1985 Total
Citations: 1 1 1 1 1 1 1 3 5 3 6 7 4 2 4 3 1 45
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (45)

Title and authors Publication Year
Handbook of Stem Cells
M Amit, J Itskovitz-Eldor
Handbook of Stem Cells 2013
Advances in Cancer Research
M Lemaire, S Deleu, ED Bruyne, EV Valckenborgh, E Menu, K Vanderkerken
Advances in Cancer Research Volume 110 2011
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MJ O'Sullivan, JA Fletcher, CA Felix
Oncology of Infancy and Childhood 2009
The Challenges of Targeting Chronic Myeloid Leukemia Stem Cells
X Jiang, C Smith, A Eaves, C Eaves
Clinical Lymphoma & Myeloma 2007
Ontogeny of natural killer cells and T cells by analysis of BCR-ABL rearrangement from patients with chronic myelogenous leukaemia
EK Cho, DS Heo, JG Seol, EJ Seo, HS Chi, ES Kim, YY Lee, BK Kim, NK Kim
British Journal of Haematology 2000
Biological and Hormonal Therapies of Cancer
KA Foon, HB Muss
1998
Chronic Granulocytic Leukemia: Recent Information on Pathogenesis, Diagnosis, and Disease Monitoring
A Tefferi, MR Litzow, P Noel, GW Dewald
Mayo Clinic Proceedings 1997
Fluorescent in situ hybridization studies of lymphocytes and neutrophils in chronic granulocytic leukemia
A Tefferi
Cancer Genetics and Cytogenetics 1995
Immunophenotype and Ultrastructural Studies in Blast Crisis of Chronic Myeloid Leukemia
C Nair, H Chorpa, S Shinde, S Barbhaya, A Kumar, S Dhond, B Yejamanam, R Sapre, A Chougule, S Advani
Leukemia & Lymphoma 1995
Occurrence of a T Cell Lymphoma in a Patient with Chronic Myeloid Leukemia Treated with Alpha Interferon
B Mahé, F Gaillard, F Labadie, S Papin, S Letortorec, P Moreau, JL Harousseau, N Milpied
Leukemia & Lymphoma 1995
Cell lineage involvement of recurrent chromosomal abnormalities in hematologic neoplasms
S Knuutila, L Teerenhovi, ML Larramendy, E Elonen, KO Franssila, SJ Nylund, T Timonen, K Heinonen, E Mahlamäki, R Winqvist, T Ruutu
Genes, Chromosomes and Cancer 1994
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F Cervantes, C Rozman
Annals of Hematology 1994
Persistence of bcr-abl mRNA-expressing cells in long-term cultures established from chronic myeloid leukemic bone marrow or blood
G Pasternak, L Pasternak
Annals of Hematology 1994
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Cancer Genetics and Cytogenetics 1994
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N Clare, K Hansen
Hematology/Oncology Clinics of North America 1994
Lack of Involvement of T-Lymphocytes in the Leukaemic Population During: Prolonged Chronic Phase of Philadelphia Chromosome Positive Chronic Myeloid Leukaemia
S Ariad, D Dajee, P Willem, WR Bezwoda
Leukemia & Lymphoma 1993
Simultaneous demonstration of the Philadelphia chromosome in T, B, and myeloid cells
AA Mackinney, SS Clark, W Borcherding, M Fizzotti, R Hong
American Journal of Hematology 1993
Chronic Myelogenous Leukemia
MH Carabasi
Cancer Investigation 1993
Immune markers in hematologic malignancies
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Critical Reviews in Oncology/Hematology 1991
Immunophenotypic, genomic and clinical characteristics of blast crisis of chronic myelogenous leukaemia
JM Hernández, R González-Sarmiento, C Martin, M González, I Sánchez*, J Corral*, A Orfao, MC Canizo, JF Miguel, A López-borrasca
British Journal of Haematology 1991
Extramedullary blast crisis in chronic myelogenous leukemia. Demonstration of t-cell lineage and philadelphia chromosome in a paraspinal tumor
T Sun, M Susin, P Koduru, EL Coffey, J Goh, J Brody, K Dittmar, R Weiss
Cancer 1991
T-lymphoid blast crisis in chronic myeloid leukemia
SH Advani, H Malhotra, PR Kadam, RS Iyer, G Nanjangud, B Balsara, T Saikia, R Gopal, CN Nair
American Journal of Hematology 1991
Long-term expression of gene introduction into normal human T-lymphocytes by retroviral-mediated gene transfer
AA Fauser
Journal of Cellular Biochemistry 1991
Molecular Genetic Medicine
JE Dick
Molecular Genetic Medicine 1991
Sequential development of peripheral T-cell lymphoma in the course of chronic myelogenous leukemia
MC Blonk, P der Valk, GC Beverstock, GJ Ossenkoppele
Cancer 1990
Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia with interferon alpha
G Egert, L Kanz, GW Löhr, AA Fauser
Blut 1990
Ontogeny of Normal Human B-Cell and T-Cell Precursors and Its Relation to Leukemogenesis
TW LeBien, JG Villablanca
Hematology/Oncology Clinics of North America 1990
Treatment of Chronic Myelogenous Leukemia with Bone Marrow Transplantation
DS Snyder, PB McGlave
Hematology/Oncology Clinics of North America 1990
The Evolving Role of Bone Marrow Transplantation in the Treatment of Chronic Myelogenous Leukemia
R Delage, J Ritz, KC Anderson
Hematology/Oncology Clinics of North America 1990
Bone Marrow Transplantation
R Champlin
Bone Marrow Transplantation 1990
Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia with interferon alpha
G Egert, L Kanz, GW Löhr, AA Fauser
Blut Zeitschrift für die Gesamte Blutforschung 1990
Laboratory and clinical applications of monoclonal antibodies for leukemias and non-Hodkin's lymphoma
KA Foon
Current Problems in Cancer 1989
Rapid decline of clonogenic hemopoietic progenitors in semisolid cultures of bone marrow samples derived from patients with chronic myeloid leukemia
U Wandl, HA Messner
The International Journal of Cell Cloning 1989
Characterization of lympho-myeloid-erythroid-megakaryocytic stem cells in peripheral blood of hairy cell leukemia patients
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Leukemia Research 1989
Ph-negative T cells in a patient with chronic myelogenous leukemia for twenty-eight years
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Leukemia Research 1989
Chronic Leukemias of Childhood
AJ Altman
Pediatric Clinics of North America 1988
Chronic Myelocytic Leukemia and Interferon
D Huhn, KP Hellriegel, N Niederle
1988
Human megakaryocytic progenitor cells
L Kanz, GW Löhr, AA Fauser
Klinische Wochenschrift 1987
Interferons regulate the in vitro differentiation of multilineage lympho-myeloid stem cells in hairy cell leukemia
R Michalevicz, M Revel
Proceedings of the National Academy of Sciences 1987
Chronic myelogenous leukaemia: a model for human cancers
RP Gale
Baillière's Clinical Haematology 1987
Survenue d'un lymphome non hodgkinien au cours d'une leucémie myéloïde chronique
R Martoïa, T Lamy, P Delmaire, JP Algayres, Y Rougier, A Laurens
La Revue de Médecine Interne 1987
Cytogenetic evidence for involvement of erythroid progenitors in a child with therapy linked myelodysplasia
HE Grier, HJ Weinstein, T Révész, PW Houlihan, CL Greenhalgh, DG Nathan, R Tantravahi
British Journal of Haematology 1986
T-cell involvement in benign phase chronic myelogenous leukemia
R Nogueira-Costa, G Spitzer, S Khorana, Q Pham, HM Kantarran, JT Manning, NG Ordonez, KA Dicke
Leukemia Research 1986
Southwestern Internal Medicine Conference: Chronic Granulocytic Leukemia: The Devastating Consequences of Genetic Instability
RG Smith
The American Journal of the Medical Sciences 1986
Establishment of the DU.528 human lymphohemopoietic stem cell line
J Kurtzberg, SH Bigner, MS Hershfield
Journal of Experimental Medicine 1985

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