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Ronald L. Nagel, … , Mary E. Fabry, Herbert Tanowitz
Published July 1, 1981
Citation Information: J Clin Invest. 1981;68(1):303-305. https://doi.org/10.1172/JCI110248.
Citation Information: J Clin Invest. 1981;68(1):303-305. https://doi.org/10.1172/JCI110248.
Abstract
HbE is a β-chain mutant frequently found among inhabitants of Southeast Asia and surrounding territories. We find that Plasmodium falciparum multiplies more slowly in erythrocytes from individuals homozygous for HbE than in cells from HbA individuals. In contrast, this parasite grows normally in erythrocytes heterozygous for HbE. This is the first direct evidence that suggests what has been suspected on the basis of circumstantial data, that HbE-containing erythrocytes might be advantageous to the carrier in regions with endemic malaria.
Authors
Ronald L. Nagel, Carmen Raventos-Suarez, Mary E. Fabry, Herbert Tanowitz
Total citations by year
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Citations to this article in year 2009 (1)
| Title and authors | Publication | Year |
|---|---|---|
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
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