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Citations to this article

Increase of adipose tissue lipoprotein lipase activity with weight loss.
R S Schwartz, J D Brunzell
R S Schwartz, J D Brunzell
Published May 1, 1981
Citation Information: J Clin Invest. 1981;67(5):1425-1430. https://doi.org/10.1172/JCI110171.
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Research Article

Increase of adipose tissue lipoprotein lipase activity with weight loss.

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Abstract

Obese subjects have elevated adipose tissue lipoprotein lipase activity per fat cell when compared with lean control subjects. This enzyme, which is rate limiting for the uptake and storage of lipoprotein triglyceride in adipose tissue, has been shown to be further elevated in a group of previously obese subjects who had been weight stable at a reduced weight for 4-28 mo. In the present prospective study of eight obese subjects, adipose tissue lipoprotein lipase activity was demonstrated to increase after weight stabilization at a reduced weight (0.33 mU/10(6) cells). In three subjects who lost weight and subsequently regained their lost weight, the enzyme activity increased after weight loss and then returned toward the original basal level with weight gain. One subject who maintained his weight loss for 10 mo. continued to have an elevated level of enzyme activity. Because adipose tissue lipoprotein lipase activity does not "normalize" after weight loss, we hypothesize that this enzyme may play a counterregulatory role in resisting deviation from a "set point" for fat mass or fat cell size and thereby predispose to reattainment of the original obese state.

Authors

R S Schwartz, J D Brunzell

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Total citations by year

Year: 2025 2024 2022 2021 2020 2019 2017 2015 2014 2013 2011 2010 2009 2007 2004 2003 2002 2001 2000 1999 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1985 1984 1983 1982 Total
Citations: 1 1 1 2 1 2 1 1 6 2 2 5 4 2 2 1 2 1 1 3 5 2 6 1 3 2 1 5 7 4 10 2 5 5 4 6 109
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article in year 2011 (2)

Title and authors Publication Year
THE EFFECT OF HEPATIC LIPASE ON CORONARY ARTERY DISEASE IN HUMANS IS INFLUENCED BY THE UNDERLYING LIPOPROTEIN PHENOTYPE
JD Brunzell, A Zambon, SS Deeb
Biochimica et Biophysica Acta 2011
The beneficial effects of HDL-C on atherosclerosis: rationale and clinical results
CG Santos-Gallego, F Torres, JJ Badimón
Clinical Lipidology 2011

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