JCI - Citations to Purinogenic Immunodeficiency Diseases: DIFFERENTIAL EFFECTS OF DEOXYADENOSINE AND DEOXYGUANOSINE ON DNA SYNTHESIS IN HUMAN T LYMPHOBLASTS

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Purinogenic Immunodeficiency Diseases: DIFFERENTIAL EFFECTS OF DEOXYADENOSINE AND DEOXYGUANOSINE ON DNA SYNTHESIS IN HUMAN T LYMPHOBLASTS

James M. Wilson, … , Peter E. Daddona, William N. Kelley

James M. Wilson, … , Peter E. Daddona, William N. Kelley

Published November 1, 1979
Citation Information: J Clin Invest. 1979;64(5):1475-1484. https://doi.org/10.1172/JCI109606.

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Citations to this article (39)

Title and authors	Publication	Year
Nonconditioned ADA-SCID gene therapy reveals ADA requirement in the hematopoietic system and clonal dominance of vector-marked clones T Uchiyama, S Takahashi, K Nakabayashi, K Okamura, K Edasawa, M Yamada, N Watanabe, E Mochizuki, T Yasuda, A Miura, M Kato, D Tomizawa, M Otsu, T Ariga, M Onodera	Molecular Therapy — Methods & Clinical Development	2021
"Reverse" carbocyclic fleximers: synthesis of a new class of adenosine deaminase inhibitors SC Zimmermann, JM Sadler, PI O'Daniel, NT Kim, KL Seley-Radtke	Nucleosides Nucleotides & Nucleic Acids	2013
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency S Delicou, V Kitra-Roussou, J Peristeri, E Goussetis, G Vessalas, E Rigatou, F Psychou, K Salavoura, S Grafakos	Pediatric Transplantation	2007
Advances in Enzymology - and Related Areas of Molecular Biology H Waelsch	Advances in Enzymology and Related Areas of Molecular Biology	2006
Tomato juice inhibits adenosine deaminase activity in human prostate tissue from patient with prostate cancer İ Durak, H Biri, A Avcı, S Sözen, E Devrim	Nutrition Research	2003
Adenosine Deaminase Prefers a Distinct Sugar Ring Conformation for Binding and Catalysis: Kinetic and Structural Studies H Ford, F Dai, L Mu, MA Siddiqui, MC Nicklaus, L Anderson, VE Marquez, JJ Barchi	Biochemistry	2000
Nucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination L Gangi-Peterson, DH Sorscher, JW Reynolds, TB Kepler, BS Mitchell	Journal of Clinical Investigation	1999
Primary Immunodeficiency Disorders: Pathogenesis and Treatment MM Eibl, HM Wolf	Clinical immunotherapeutics	1996
Immunoglobulin Genes PD Burrows, HW Schroeder, MD Cooper	Immunoglobulin Genes	1995
Interaction between ABO blood groups and ADA genetic polymorphism during intrauterine life: A comparative analysis of couples with habitual abortion and normal puerperae delivering a live-born infant N Lucarini, M Nicotra, F Gloria-Bottini, P Borgiani, A Amante, C Muttinelli, F Signoretti, ML Torre, E Bottini	Human Genetics	1995
Adenosine deaminase, 5′-nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in gastric juices from patients with gastric cancer, ulcer, and atrophic gastritis I Durak, N Örmeci, Ö Akyol, O Canbolat, M Kavutçu, M Bülbül	Digestive Diseases and Sciences	1994
Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP DS Duan, T Nagashima, T Hoshino, F Waldman, K Pawlak, W Sadee	Biochemical Journal	1990
Approaches to Gene Therapy in Disorders of Purine Metabolism JA Wolff, T Friedmann	Rheumatic diseases clinics of North America	1988
Activities of purine metabolising enzymes in lymphocytes of neonates and young children: correlates with immune function JA Renouf, YH Thong, AH Chalmers	Immunology Letters	1987
Deoxyadenosine triphosphate as a mediator of deoxyguanosine toxicity in cultured T lymphoblasts GJ Mann, RM Fox	Journal of Clinical Investigation	1986
Evaluation of adenosine deaminase activity in patients with head and neck cancer KS Dasmahapatra, HZ Hill, A Dasmahapatra, S Suarez	Journal of Surgical Research	1986
Biochemical Consequences of Adenosine Deaminase Inhibition in Vivo BS Mitchell, Y Sidi, M Hershfield, CA Koller	Annals of the New York Academy of Sciences	1985
Changes in deoxynucleoside triphosphate pools induced by inhibitors and modulators of ribonucleotide reductase RM Fox	Pharmacology & Therapeutics	1985
Immunodeficiencies Associated with Errors in Purine Metabolism NL Edwards	Medical Clinics of North America	1985
2'-deoxyguanosine toxicity for B and mature T lymphoid cell lines is mediated by guanine ribonucleotide accumulation Y Sidi, BS Mitchell	Journal of Clinical Investigation	1984
The effect of G2-treatments with 2?-deoxyadenosine on the frequency of chromatid aberrations in human lymphocytes depends on the type of culture BA Kihlman, HC Andersson	Chromosoma	1984
Effect of combinations of deoxyguanosine and 8-aminoguanosine with 2,3-dihydro-1H-imidazo[1,2-b]pyrazole on L1210 cell crowth in culture A Sato, PE Bacon, SW Schneller, JG Cory	Biochemical Pharmacology	1984
The mechanism of inhibition and “reversal” of mitogen-induced lymphocyte activation in a model of purine-nucleoside phosphorylase deficiency D Albert, HG Bluestein, RC Willis, K Nette, JE Seegmiller	Cellular Immunology	1984
Metabolism of deoxynucleosides by lymphocytes in long-term culture deficient in different purine enzymes HA Simmonds, A Goday, GS Morris, M Foppe, J Brolsma	Biochemical Pharmacology	1984
Altered cell cycle distributions of cultured human lymphoblasts during cytotoxicity related to adenosine deaminase inhibition J Faller, TD Palella, P Dean, IH Fox	Metabolism	1984
In vitro metabolism of deoxycoformycin in human T lymphoblastoid cells. Phosphorylation of deoxycoformycin and incorporation into cellular DNA MF Siaw, MS Coleman	The Journal of biological chemistry	1984
The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase deficiency WR Osborne, CR Scott	Biochemical Journal	1983
Metabolism of purine nucleosides in human and ovine lymphocytes and rat thymocytes and their influence on mitogenic stimulation GJ Peters, A Ooterhof, JH Veerkamp	Biochimica et Biophysica Acta (BBA) - General Subjects	1983
Effect of purine nucleoside phosphorylase substrates on the mitogen-induced stimulation of murine T and B spleen cells R Martineau, J Willemot	Immunopharmacology	1983
Effect of immunosuppressive agents on human T and B lymphoblasts IS Kazmers, PE Daddona, AP Dalke, WN Kelley	Biochemical Pharmacology	1983
Consequences of adenosine deaminase deficiency on thymocyte metabolism L Thuillier, F Garreau, PH Cartier	European Journal of Immunology	1981
Metabolic basis for disorders of purine nucleotide degradation IH Fox	Metabolism	1981
Characteristics of an aminohydrolase distinct from adenosine deaminase in cultured human lymphoblasts PE Daddona, WN Kelley	Biochimica et Biophysica Acta (BBA) - Enzymology	1981
Deoxycoformycin: Neurological toxicity PP Major, RP Agarwal, DW Kufe	Cancer Chemotherapy and Pharmacology	1981
Adenosine deaminase polymorphism. Associations at clinical level suggest a role in cell functions and immune reactions E Bottini, E Carapella, L Cataldi, M Nicotra, P Lucarelli, N Lucarini, R Pascone, F Gloria-Bottini	Journal of medical genetics	1981
Inhibition of Purine Nucleoside Phosphorylase by 8-Aminoguanosine: Selective Toxicity for T Lymphoblasts IS Kazmers, BS Mitchell, PE Dadonna, LL Wotring, LB Townsend, WN Kelley	Science	1981
ATP depletion as a consequence of adenosine deaminase inhibition in man MF Siaw, BS Mitchell, CA Koller, MS Coleman, JJ Hutton	Proceedings of the National Academy of Sciences	1980
Purine Nucleoside Phosphorylase Deficiency: Improved Metabolic and Immunologic Function with Erythrocyte Transfusions KC Rich, E Mejias, IH Fox	New England Journal of Medicine	1980
Contemporary Metabolism N Freinkel		1979

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