Citations to this article

Effects of Intraduodenal Administration of HCl and Glucose on Circulating Immunoreactive Secretin and Insulin Concentrations
Guenther Boden, … , Frederick A. Reichle, Walter Saraga
Guenther Boden, … , Frederick A. Reichle, Walter Saraga
Published April 1, 1974
Citation Information: J Clin Invest. 1974;53(4):1185-1193. https://doi.org/10.1172/JCI107657.
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Research Article

Effects of Intraduodenal Administration of HCl and Glucose on Circulating Immunoreactive Secretin and Insulin Concentrations

Abstract

A new radioimmunoassay for secretin was used to investigate (a) serum secretin responses to intraduodenally infused HCl and glucose, (b) the metabolic half-life and the volume of distribution of exogenous secretin and (c) the effect of endogenously released secretin on insulin secretion in 25 anesthetized dogs. Portal and femoral venous blood samples were taken simultaneously before, during, and after intraduodenal infusion of HCl (21 meq/30 min) and glucose (131 ml/30 min). Control experiments were performed with intraduodenal infusion of saline.

Authors

Guenther Boden, Noorjehan Essa, Oliver E. Owen, Frederick A. Reichle, Walter Saraga

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Citations to this article in year 2010 (2)

Title and authors Publication Year
Central and Peripheral Administration of Secretin Inhibits Food Intake in Mice through the Activation of the Melanocortin System
CY Cheng, JY Chu, BK Chow 		Neuropsychopharmacology 2010
Vitamins & Hormones
KJ Hare, FK Knop 		Vitamins & Hormones 2010

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