The immune response of C57BL/6 mice to allogeneic (DBA/2) mastocytoma cell suspensions was profoundly suppressed by intraperitoneal administration of 1 μg cholera enterotoxin 4 days after antigenic stimulation. The immune response assayed 11 days after antigen showed decreased cytolytically active thymusderived (T) lymphocytes and markedly depressed serumagglutinating titers. A comparable suppression of the immune response to skin allografts (DBA/2→C57BL/6) was also effected by cholera toxin administration, although there was no prolongation of allograft survival.
Christopher S. Henney, Lawrence M. Lichtenstein, Elizabeth Gillespie, Ronald T. Rolley
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Regulation of asthma-related T-cell cytokines by the cyclic AMP-dependent signalling pathway
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Clinical & Experimental Allergy | 2000 |
Peripheral blood T lymphocytes from asthmatic patients are primed for enhanced expression of interleukin (IL)-4 and IL-5 mRNA: associations with lung function and serum IgE
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Clinical & Experimental Allergy | 1999 |
Comparison of Immunological Effects of Cholera Toxin on Autoimmune MRL/lpr and BXSB Mice
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Microbiology and Immunology | 1992 |
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Immunoadjuvant effects of periodontitis-associated bacteria
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M Plaut, RP Schleimer |
Annals of the New York Academy of Sciences | 1988 |
cAMP antagonizes interleukin 2-promoted T-cell cycle progression at a discrete point in early G1
KW Johnson, BH Davis, KA Smith |
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Modulating action of Escherichia coli heat-stable enterotoxin (STa) on the humoral immune response
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Inhibitory effect of cholera toxin on human natural cell-mediated cytotoxicity and its augmentation by interferon
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International Journal of Cancer | 1981 |
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MR Escobar, H Friedman |
1980 | |
Suppression of local intestinal immunoglobulin A immune response to cholera toxin by subcutaneous administration of cholera toxoids
SR Hamilton, JH Yardley, GD Brown |
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Immunological Aspects of Cancer
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Experimental Models of Chronic Inflammatory Diseases
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The Specificity and Action of Animal, Bacterial and Plant Toxins
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Stimulation of monocyte cGMP by leukocyte dialysates. An antigen-independent property of dialyzable transfer factor
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STIMULATION OF cAMP LEVELS AND MODULATION OF ANTIBODY FORMATION IN MICE IMMUNIZED WITH CHOLERA TOXIN
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Suppression of the immune response by microorganisms
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Modulation of antibody synthesis by cholera exotoxin: Influence on helper thymocytes
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Cholera
CC Carpenter |
Preventive Medicine | 1974 |
On the relation of products of activated lymphocytes to cell-mediated cytolysis
CS Henney, J Gaffney, BR Bloom |
Journal of Experimental Medicine | 1974 |
Killer T Cells
CS Henney |
New England Journal of Medicine | 1974 |
Cyclic AMP, Cell Growth, and the Immune Response
W Braun, LM Lichtenstein, CW Parker |
1974 | |
Modulation of Inflammation and Immunity by Cyclic AMP: Receptors for vasoactive hormones and mediators of inflammation regulate many leukocyte functions
HR Bourne, Y Weinstein, KL Melmon, LM Lichtenstein, CS Henney, GM Shearer |
Science | 1974 |
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BB Levine |
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Current Topics in Microbiology and Immunology
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