JCI - Citations to Resistance to Symptomatic Insulin Reactions after Fasting

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Resistance to Symptomatic Insulin Reactions after Fasting

Ernst J. Drenick, … , Gabor C. Tamasi, Arnold S. Brickman

Ernst J. Drenick, … , Gabor C. Tamasi, Arnold S. Brickman

Published October 1, 1972
Citation Information: J Clin Invest. 1972;51(10):2757-2762. https://doi.org/10.1172/JCI107095.

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Citations to this article (74)

Title and authors	Publication	Year
The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer. Seyfried TN, Lee DC, Duraj T, Ta NL, Mukherjee P, Kiebish M, Arismendi-Morillo G, Chinopoulos C	Journal of bioenergetics and biomembranes	2025
From starvation to time-restricted eating: a review of fasting physiology. Rebello CJ, Zhang D, Anderson JC, Bowman RF, Peeke PM, Greenway FL	International journal of obesity (2005)	2024
Refueling the post COVID-19 brain: potential role of ketogenic medium chain triglyceride supplementation: an hypothesis. Juby AG, Cunnane SC, Mager DR	Frontiers in Nutrition	2023
Metabolic management of microenvironment acidity in glioblastoma Seyfried TN, Arismendi-Morillo G, Zuccoli G, Lee DC, Duraj T, Elsakka AM, Maroon JC, Mukherjee P, Ta L, Shelton L, D'Agostino D, Kiebish M, Chinopoulos C	Frontiers in Oncology	2022
Tumor acidity: From hallmark of cancer to target of treatment Bogdanov A, Bogdanov A, Chubenko V, Volkov N, Moiseenko F, Moiseyenko V	Frontiers in Oncology	2022
Use of medium chain triglyceride (MCT) oil in subjects with Alzheimer's disease: A randomized, double-blind, placebo-controlled, crossover study, with an open-label extension. Juby AG, Blackburn TE, Mager DR		2022
Macronutrient Proportions and Fat Type Impact Ketogenicity and Shape the Circulating Lipidome in Dogs. Jackson MI	Metabolites	2022
Efficacy of Glucose Starvation of Cancer Cells in the Progress of Oral Squamous Cell Carcinoma Induced in Hamster. Zakaraia S, Takkem A, Redwan H, Barakat C	Asian Pacific Journal of Cancer Prevention	2022
Still Excited, but Less Aroused-The Effects of Nutritional Ketosis on Epinephrine Response and Hypothalamic Orexin Neuron Activation Following Recurrent Hypoglycemia in Diabetic Rats. Nedoboy PE, Farnham MM	Metabolites	2022
Carbohydrate Restriction for Diabetes: Rediscovering Century-Old Wisdom Belinda S Lennerz, Andrew P. Koutnik, Svetlana Azova, Joseph I. Wolfsdorf, David Ludwig	Journal of Clinical Investigation	2021
Slow but Steady—The Responsiveness of Sympathoadrenal System to a Hypoglycemic Challenge in Ketogenic Diet-Fed Rats PE Nedoboy, M Cohen, MM Farnham	Nutrients	2021
Can the Mitochondrial Metabolic Theory Explain Better the Origin and Management of Cancer than Can the Somatic Mutation Theory? TN Seyfried, C Chinopoulos	Metabolites	2021
Effect of medium chain fatty acid in human health and disease PG Roopashree, SS Shetty, NS Kumari	Journal of Functional Foods	2021
Ketones: potential to achieve brain energy rescue and sustain cognitive health during ageing É Myette-Côté, A Soto-Mota, SC Cunnane	British Journal of Nutrition	2021
Ketone Supplementation: Meeting the Needs of the Brain in an Energy Crisis. Poff AM, Moss S, Soliven M, D'Agostino DP	Frontiers in Nutrition	2021
Cellular Specificity and Inter-cellular Coordination in the Brain Bioenergetic System: Implications for Aging and Neurodegeneration G Qi, Y Mi, F Yin	Frontiers in physiology	2020
Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections BJ Stubbs, AP Koutnik, EL Goldberg, V Upadhyay, PJ Turnbaugh, E Verdin, JC Newman	The American Journal of Medicine	2020
Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer’s disease. A systematic review and meta-analysis of human studies KI Avgerinos, JM Egan, MP Mattson, D Kapogiannis	Ageing Research Reviews	2020
Caprylic (Octanoic) Acid as a Potential Fatty Acid Chemotherapeutic for Glioblastoma MA Altinoz, A Ozpinar, TN Seyfried	Prostaglandins, leukotrienes, and essential fatty acids	2020
Functional Metabolomics Reveals that Astragalus Polysaccharides Improve Lipids Metabolism through Microbial Metabolite 2-Hydroxybutyric Acid in Obese Mice B Li, Y Hong, Y Gu, S Ye, K Hu, J Yao, K Ding, A Zhao, W Jia, H Li	Engineering	2020
Edible dairy formula fortified with coconut oil for neuroprotection against aluminium chloride-induced Alzheimer's disease in rats HM Khalil, HH Salama, AK Al-Mokaddem, SH Aljuaydi, AE Edris	Journal of Functional Foods	2020
A ketogenic drink improves brain energy and cognition in MCI Mélanie Fortier, Christian-Alexandre Castellano, Etienne Croteau, Francis Langlois, Christian Bocti, Valérie St-Pierre, Camille Vandenberghe, Michaël Bernier, Maggie Roy, Maxime Descoteaux, Kevin Whittingstall, Martin Lepage, Eric E. Turcotte, Tamas Fulop, Stephen Cunnane	Alzheimer's & dementia : the journal of the Alzheimer's Association	2019
Plasma Ketone and Medium Chain Fatty Acid Response in Humans Consuming Different Medium Chain Triglycerides During a Metabolic Study Day V St-Pierre, C Vandenberghe, CM Lowry, M Fortier, CA Castellano, R Wagner, SC Cunnane	Frontiers in Nutrition	2019
Medical foods in Alzheimer’s disease KW Lange, J Guo, S Kanaya, KM Lange, Y Nakamura, S Li	Food Science and Human Wellness	2019
Glial acetate metabolism is increased following a 72-h fast in metabolically healthy men and correlates with susceptibility to hypoglycemia DH McDougal, MM Darpolor, MA DuVall, EF Sutton, CD Morrison, KM Gadde, LM Redman, OT Carmichael	Acta Diabetologica	2018
Mitochondrial Substrate-Level Phosphorylation as Energy Source for Glioblastoma: Review and Hypothesis C Chinopoulos, TN Seyfried	ASN NEURO	2018
A short-term intervention combining aerobic exercise with medium-chain triglyceride (MCT) is more ketogenic than either MCT or aerobic exercise alone: A comparison of normoglycemic and pre-diabetic older women C Vandenberghe, CA Castellano, M Maltais, M Fortier, V St-Pierre, IJ Dionne, SC Cunnane	Applied Physiology, Nutrition, and Metabolism	2018
Wilhelm Brünings' forgotten contribution to the metabolic treatment of cancer utilizing hypoglycemia and a very low carbohydrate (ketogenic) diet RJ Klement	Journal of traditional and complementary medicine	2018
Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study SJ Hallberg, AL McKenzie, PT Williams, NH Bhanpuri, AL Peters, WW Campbell, TL Hazbun, BM Volk, JP McCarter, SD Phinney, JS Volek	Diabetes Therapy	2018
Ketones, omega-3 fatty acids and the Yin-Yang balance in the brain: insights from infant development and Alzheimer’s disease, and implications for human brain evolution SC Cunnane	OCL	2018
A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes AL McKenzie, SJ Hallberg, BC Creighton, BM Volk, TM Link, MK Abner, RM Glon, JP McCarter, JS Volek, SD Phinney		2017
Butyrate is more ketogenic than leucine or octanoate-monoacylglycerol in healthy adult humans V St-Pierre, A Courchesne-Loyer, C Vandenberghe, M Hennebelle, CA Castellano, SC Cunnane	Journal of Functional Foods	2017
Ketogenic diets and Alzheimer’s disease KW Lange, KM Lange, E Makulska-Gertruda, Y Nakamura, A Reissmann, S Kanaya, J Hauser	Food Science and Human Wellness	2017
Emulsification Increases the Acute Ketogenic Effect and Bioavailability of Medium-Chain Triglycerides in Humans A Courchesne-Loyer, CM Lowry, V St-Pierre, C Vandenberghe, M Fortier, CA Castellano, JR Wagner, SC Cunnane		2017
Tricaprylin Alone Increases Plasma Ketone Response More Than Coconut Oil or Other Medium-Chain Triglycerides: An Acute Crossover Study in Healthy Adults C Vandenberghe, V St-Pierre, T Pierotti, M Fortier, CA Castellano, SC Cunnane		2017
Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease SC Cunnane, A Courchesne-Loyer, C Vandenberghe, V St-Pierre, M Fortier, M Hennebelle, E Croteau, C Bocti, T Fulop, CA Castellano	Frontiers in molecular neuroscience	2016
Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease: Brain glucose and ketone uptake in Alzheimer's disease SC Cunnane, A Courchesne-Loyer, V St-Pierre, C Vandenberghe, T Pierotti, M Fortier, E Croteau, CA Castellano	Annals of the New York Academy of Sciences	2016
Endocrinology C Napier, SH Pearce	Endocrinology	2016
Inverse relationship between brain glucose and ketone metabolism in adults during short-term moderate dietary ketosis: A dual tracer quantitative positron emission tomography study A Courchesne-Loyer, E Croteau, CA Castellano, V St-Pierre, M Hennebelle, SC Cunnane	Journal of Cerebral Blood Flow & Metabolism	2016
Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice JJ Meidenbauer, N Ta, TN Seyfried	Nutrition & Metabolism	2014
Starvation of cancer via induced ketogenesis and severe hypoglycemia A Kapelner, M Vorsanger	Medical Hypotheses	2014
Metabolic therapy: A new paradigm for managing malignant brain cancer TN Seyfried, R Flores, AM Poff, DP D’Agostino, P Mukherjee	Cancer Letters	2014
Cancer as a metabolic disease: implications for novel therapeutics TN Seyfried, RE Flores, AM Poff, DP D'Agostino	Carcinogenesis	2013
Oral β-Hydroxybutyrate Supplementation in Two Patients with Hyperinsulinemic Hypoglycemia: Monitoring of β-Hydroxybutyrate Levels in Blood and Cerebrospinal Fluid, and in the Brain by In Vivo Magnetic Resonance Spectroscopy B Plecko, S Stoeckler-Ipsiroglu, E Schober, G Harrer, V Mlynarik, S Gruber, E Moser, D Moeslinger, H Silgoner, O Ipsiroglu	Pediatric Research	2002
Treating obese patients with poorly controlled diabetes: confessions of an insulin therapist D Kerr, D Cavan	Diabetes/Metabolism Research and Reviews	1999
Reduced Counterregulation during Hypoglycemia with Raised Circulating Nonglucose Lipid Substrates: Evidence for Regional Differences in Metabolic Capacity in the Human Brain? ML Evans, K Matyka, J Lomas, A Pernet, IC Cranston, I Macdonald, SA Amiel	The Journal of clinical endocrinology and metabolism	1998
Hypoglycaemia-Real and Unreal, Lawful and Unlawful: The 1994 Banting Lecture V Marks	Diabetic Medicine	1995
Nutrition of the brain: macronutrient supply SA Amiel	Proceedings of the Nutrition Society	1994
Stimulatory influence of d(−)3-hydroxybutyrate feeding on sympathetic nervous system activity in the rat J Kolanowski, JB Young, L Landsberg	Metabolism	1994
Hypoglycemia counterregulation in elderly humans: relationship to glucose levels FJ Ortiz-Alonso, A Galecki, WH Herman, MJ Smith, JA Jacquez, JB Halter	American journal of physiology. Endocrinology and metabolism	1994
Effect of hypoglycemia on changes of brain lactic acid and intracellular pH produced by ischemia Y Nagai, S Naruse, MW Weiner	NMR in Biomedicine	1993
Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans C Fanelli, AD Vincenzo, F Modarelli, M Lepore, M Ciofetta, L Epifano, S Pampanelli, P Brunetti, GB Bolli	Diabetologia	1993
Patients with Type 1 Diabetes Adapt Acutely to Sustained Mild Hypoglycaemia D Kerr, IA Macdonald, RB Tattersall	Diabetic Medicine	1991
Diabeic Ketoacidosis WT Cefalu	Critical Care Clinics	1991
Fasting for 72 h decreases the responses of counterregulatory hormones to insulin-induced hypoglycaemia in normal man U Adamson, PE Lins, V Grill	Scandinavian Journal of Clinical & Laboratory Investigation	1989
Adaptation to mild hypoglycaemia in normal subjects despite sustained increases in counter-regulatory hormones D Kerr, IA Macdonald, RB Tattersall	Diabetologia	1989
New Vistas in Chronic Schizophrenia F Lichtigfeld, R Sandyk, M Gillman	International Journal of Neuroscience	1988
Nephrology Forum JJ Cohen, JT Harrington, JP Kassirer		1983
Fasting: the history, pathophysiology and complications PR Kerndt, JL Naughton, CE Driscoll, DA Loxterkamp	The Western journal of medicine	1982
Nondetectable plasma glucose levels after insulin administration in the American bullfrog (Rana catesbeiana) R deRoos, AV Parker	General and Comparative Endocrinology	1982
Ciba Foundation Symposium 87 - Metabolic Acidosis: Ciba/Metabolic R Porter, G Lawrenson		1982
Ketosis GF Cahill	Kidney International	1981
Fasting energy utilization in the smaller of twins with epinephrine-deficient hypoglycemia DS Kerr, OG Brooke, HM Robinson	Metabolism	1981
Fourth Annual Jonathan E. Rhoads Lecture: ketosis GF Cahill	JPEN. Journal of parenteral and enteral nutrition	1981
Hormones and Energy Metabolism DM Klachko, RR Anderson, M Heimberg		1979
Fasting, Feeding and Regulation of the Sympathetic Nervous System HL Bleich, ES Boro, L Landsberg, JB Young	New England Journal of Medicine	1978
Homeostasis During Hypoglycemia: Central Control of Adrenal Secretion and Peripheral Control of Feeding EM Stricker, N Rowland, CF Saller, MI Friedman	Science	1977
Suppression of Sympathetic Nervous System During Fasting JB Young, L Landsberg	Science	1977
Lack of central autonomic regulation of substrate during early fasting in man RG Brodows, RG Campbell, AJ Al-Aziz, FX Pi-Sunyer	Metabolism	1976
Ketotic hypoglycaemia of childhood AM Pierides, J Anderson, JM Stansfeld	Postgraduate medical journal	1975
Renal conservation of ketone bodies during starvation DG Sapir, OE Owen	Metabolism	1975
Hepatic Ketogenesis and Gluconeogenesis in Humans AJ Garber, PH Menzel, G Boden, OE Owen	Journal of Clinical Investigation	1974
Comparative measurements of glucose, beta-hydroxybutyrate, acetoacetate, and insulin in blood and cerebrospinal fluid during starvation OE Owen, GA Reichard, G Boden, C Shuman	Metabolism	1974
Effects of ketone body infusion on hypoglycemic reaction in postabsorptive dogs JP Flatt, GL Blackburn, G Randers, JB Stanbury	Metabolism	1974

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