Fetal renal function in the sheep was investigated in a chronic preparation which permitted repeated evaluations of urine flow and osmolality as well as renal clearances in animals which were unanesthetized and remote from acute surgical stress. Measurements of fetal blood pressure, pH, osmolality, fetal growth in utero, and final outcome did not indicate an adverse effect of the experimental procedure on the fetus.
Edwin L. Gresham, John H. G. Rankin, Edgar L. Makowski, Giacomo Meschia, Frederick C. Battaglia
Title and authors | Publication | Year |
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Obstetrics: Normal and Problem Pregnancies
MC Gordon |
Obstetrics: Normal and Problem Pregnancies | 2007 |
Amniotic Fluid Water Dynamics
MH Beall, JP Wijngaard, MJ Gemert, MG Ross |
Placenta | 2007 |
The Use of Microdialysis for the Study of Drug Kinetics: Central Nervous System Pharmacokinetics of Diphenhydramine in Fetal, Newborn, and Adult Sheep
SC Au-Yeung, KW Riggs, N Gruber, DW Rurak |
Drug Metabolism and Disposition | 2007 |