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Citations to this article

Deposition in and release of vitamin D3 from body fat: evidence for a storage site in the rat
Saul J. Rosenstreich, … , Clayton Rich, Wade Volwiler
Saul J. Rosenstreich, … , Clayton Rich, Wade Volwiler
Published March 1, 1971
Citation Information: J Clin Invest. 1971;50(3):679-687. https://doi.org/10.1172/JCI106538.
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Research Article Article has an altmetric score of 10

Deposition in and release of vitamin D3 from body fat: evidence for a storage site in the rat

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Abstract

Vitamin D in all body tissues was radio-labeled by supplementing completely vitamin D-deficient weanling rats with oral vitamin D3-4-14C for 2 wk. All vitamin D was then withheld, and radioactivity and vitamin D content in a variety of organs and tissues were measured. Adipose tissue was found to contain by far the greatest quantity of radioactivity throughout the 3 month experimental period. Immediately after supplementation, half of the total radioactivity in adipose tissue corresponded to unaltered vitamin D3, and the other half to polar metabolites and esters of vitamin D3 and unidentified peak II. 1 month later there was approximately the same proportion but a decrease in the total quantity of each form. We conclude that adipose tissue is the major storage site for vitamin D3 in its several forms. Unaltered vitamin D3 was the principal storage form observed and presumably a source available for conversion to other metabolites during deprivation.

Authors

Saul J. Rosenstreich, Clayton Rich, Wade Volwiler

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Total citations by year

Year: 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2002 2001 2000 1999 1998 1995 1993 1988 1987 1986 1985 1983 1982 1981 1980 1979 1978 1977 1976 1975 1974 1973 1972 1960 Total
Citations: 1 6 7 11 6 12 8 13 12 10 18 9 10 6 7 5 6 2 4 2 2 2 1 1 2 1 4 1 1 1 3 2 1 2 1 3 1 3 2 1 3 3 1 197
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Citations to this article in year 2006 (4)

Title and authors Publication Year
The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans
LB Yanoff, SJ Parikh, A Spitalnik, B Denkinger, NG Sebring, P Slaughter, T McHugh, AT Remaley, JA Yanovski
Clinical Endocrinology 2006
UVB-induced production of 1,25-dihydroxyvitamin D3 and vitamin D activity in human keratinocytes pretreated with a sterol Δ7-reductase inhibitor
K Vantieghem, AM Kissmeyer, PD Haes, R Bouillon, S Segaert
Journal of Cellular Biochemistry 2006
Vitamin D Status and the Metabolic Syndrome
LA Martini, RJ Wood
Nutrition Reviews 2006
Vitamin D and its binding protein Gc: Long‐term variability in peri‐ and postmenopausal women with and without hormone replacement therapy
L Rejnmark, AL Lauridsen, C Brot, P Vestergaard, L Heickendorff, E Nexo, L Mosekilde
Scandinavian Journal of Clinical & Laboratory Investigation 2006

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