Citations to this article

Changes in bone sodium and carbonate in metabolic acidosis and alkalosis in the dog
James M. Burnell
James M. Burnell
Published February 1, 1971
Citation Information: J Clin Invest. 1971;50(2):327-331. https://doi.org/10.1172/JCI106499.
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Research Article

Changes in bone sodium and carbonate in metabolic acidosis and alkalosis in the dog

Abstract

Metabolic acidosis and alkalosis were produced in adult dogs over 5- to 10-day periods. Midtibial cortical bone was analyzed for calcium, sodium, phosphorus, and carbonate. In acidosis bone CO3/Ca decreased 9.5% and bone Na/Ca decreased 6.3%. In alkalosis bone CO3/Ca increased 3.1% and bone Na/Ca increased 3.0%.

Authors

James M. Burnell

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