To explore the relation between androgens and prostatic hypertrophy in man, the concentrations of testosterone, dihydrotestosterone, and androstenedione and the rate of conversion of testosterone to dihydrotestosterone have been measured in normal and hypertrophic prostate tissue. First, a double isotope derivative technique was adapted for the measurement of tissue androgen content in 15 normal and 10 hypertrophic prostates. Although there was no significant difference in the content of androstenedione and testosterone between the two types of tissue, the content of dihydrotestosterone was significantly greater in the hypertrophic tissue (0.60 ±0.10 μg/100 g) than in the normal glands (0.13 ±0.05 μg/100 g). Second, a regional study was performed in three normal prostates and four glands with early hypertrophy, and it was demonstrated that the dihydrotestosterone content was two and three fold greater in the periurethral area where prostatic hypertrophy usually commences than in the outer regions of the gland. Finally, the rate of conversion of testosterone to dihydrotestosterone has been measured under standardized conditions in tissue slices from 4 normal and 20 hypertrophic prostates. There was no significant difference in the rate of dihydrotestosterone formation between the two types of gland (6.0 ±0.8 and 7.8 ±0.5 μμmoles/15 mg of tissue per hr). While the mechanism by which dihydrotestosterone accumulation occurs remains unexplained, it is possible that the local accumulation of dihydrotestosterone may be involved in the pathogenesis of prostatic hypertrophy in man.
Pentti K. Siiteri, Jean D. Wilson
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Title and authors | Publication | Year |
---|---|---|
Circulating levels of blood biomarkers and risk of benign prostatic hyperplasia: Results from two large cohorts in Europe and East Asia
Liu S, Liu X, Song P, Yang L, Liu Z, Zhou J, Wang L, Yan X, Ma K, Yu Y, Wang X, Dong Q |
Journal of Global Health | 2024 |
Echotexture Analysis of Prostate Parenchyma for Detection of Benign Prostatic Hyperplasia in Dogs
MH Khanbazi, A Mogheiseh, MS Khafi, S Nazifi, N Derakhshandeh, K Golchin-rad |
Topics in Companion Animal Medicine | 2021 |
An investigation on the relevance of prolactin, insulin‐like growth factor‐1 and 25‐hydroxyvitamin D 3 (25‐OHD 3 ) in canine benign prostatic hyperplasia in a predisposed breed model
FW Beining, M Schmicke, M Wilkens, K Wolf, K Rohn, AR GünzelApel |
Veterinary Medicine and Science | 2021 |
Determination of Intraprostatic and Intratesticular Androgens
M Šimková, J Heráček, P Drašar, R Hampl |
International journal of molecular sciences | 2021 |
A tribute to Jean D. Wilson (1932–2021)
JL Jameson |
Journal of Clinical Investigation | 2021 |
The Effects of Aronia melanocarpa Extract on Testosterone-Induced Benign Prostatic Hyperplasia in Rats, and Quantitative Analysis of Major Constituents Depending on Extract Conditions
NH Kim, J Jegal, YN Kim, JD Heo, JR Rho, MH Yang, EJ Jeong |
Nutrients | 2020 |
Entwicklung einer großen intraprostatischen Zyste nach Einsatz eines GnRH-Agonist-Implantats bei einem Rüden mit benigner Prostatahyperplasie
P Socha, T Janowski, S Zduńczyk |
Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere | 2020 |
Benign prostatic hyperplasia - what do we know?: What we know on BPH
CM Devlin, MS Simms, NJ Maitland |
BJU International | 2020 |
Changes in the serum prostatic biomarkers during the treatment of benign prostatic hyperplasia with a 5alpha-reductase inhibitor: finasteride
K Golchin-Rad, A Mogheiseh, S Nazifi, MS Khafi, N Derakhshandeh, M Abbaszadeh-Hasiri |
Topics in Companion Animal Medicine | 2020 |
Myometrial activation: Novel concepts underlying labor
O Shynlova, L Nadeem, J Zhang, C Dunk, S Lye |
Placenta | 2020 |
Perfusion change in benign prostatic hyperplasia before and after castration in a canine model: Contrast enhanced ultrasonography and CT perfusion study
S Yoon, MM Alfajaro, KO Cho, US Choi, H Je, J Jung, Y Jang, J Choi |
Theriogenology | 2020 |
Reprint of: Myometrial activation: Novel concepts underlying labor
O Shynlova, L Nadeem, J Zhang, C Dunk, S Lye |
Placenta | 2020 |
Prostatic Artery Embolization
AJ Isaacson, S Bagla, MC Raynor, H Yu |
2019 | |
Corrigendum to “Validation of a testosterone and dihydrotestosterone liquid chromatography tandem mass spectrometry assay: interference and comparison with established methods” [Steroids Volume 73, Issue 13, 12 December 2008, Pages 1345-1352]
C Wang, S Shiraishi, A Leung, S Baravarian, L Hull, V Goh, PW Lee, RS Swerdloff |
Steroids | 2018 |
Androgen action in prostate function and disease
Partha P Banerjee, Subhadra Banerjee, Terry R Brown, Barry R Zirkin |
American journal of clinical and experimental urology | 2018 |
Anti-Proliferative Effects of HBX-5 on Progression of Benign Prostatic Hyperplasia
BR Jin, HJ Kim, SK Park, MS Kim, KH Lee, IJ Yoon, HJ An |
Molecules (Basel, Switzerland) | 2018 |
Comparative Aspects of Pre- and Postnatal Development of the Male Reproductive System: Development of the Male Reproductive System
CA Picut, MK Ziejewski, D Stanislaus |
Birth Defects Research Part A Clinical and Molecular Teratology | 2017 |
Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study
M Habibi, R Mirfakhraie, M Khani, A Rakhshan, E Azargashb, F Pouresmaeili |
Gene | 2017 |
Testosterone and dihydrotestosterone levels in the transition zone correlate with prostate volume
T Pejčić, T Tosti, Ž Tešić, B Milković, D Dragičević, M Kozomara, M Čekerevac, Z Džamić |
The Prostate | 2017 |
CLINICOPATHOLOGICAL STUDY OF PROSTATE BIOPSY IN PATIENTS RECEIVING DUTASTERIDE FOR BENIGN PROSTATIC HYPERPLASIA
T Endo, N Kamiya, M Yano, R Oka, FC Lee, T Utsumi, S Kamijima, D Nishimi, M Takanami, N Hiruta, H Suzuki |
The Japanese Journal of Urology | 2015 |
Landmarks in BPH—from aetiology to medical and surgical management
A Kahokehr, PJ Gilling |
Nature Reviews Urology | 2014 |
Phytoandrogenic properties of Eurycoma longifolia as natural alternative to testosterone replacement therapy
A George, R Henkel |
Andrologia | 2014 |
Reference Module in Biomedical Sciences
DL Sackett, RB Haynes |
2014 | |
Male Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia: Kaplan/Male Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia
C Füllhase, R Soler |
Male Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia: Kaplan/Male Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia | 2014 |
The role of chronic prostatic inflammation in the pathogenesis and progression of benign prostatic hyperplasia (BPH): Chronic prostatic inflammation in BPH pathogenesis and progression
G Gandaglia, A Briganti, P Gontero, N Mondaini, G Novara, A Salonia, A Sciarra, F Montorsi |
BJU International | 2013 |
Clinical biochemistry of dihydrotestosterone
PM Marchetti, JH Barth |
Annals of Clinical Biochemistry | 2013 |
Methods in Enzymology
JD Stone, AS Chervin, DH Aggen, DM Kranz |
Protein Engineering for Therapeutics Part B | 2012 |
PPARγ: a molecular link between systemic metabolic disease and benign prostate hyperplasia
M Jiang, DW Strand, OE Franco, PE Clark, SW Hayward |
Differentiation | 2011 |
Estrogen and androgen signaling in the pathogenesis of BPH
CK Ho, FK Habib |
Nature Reviews Urology | 2011 |
Intraprostatic testosterone and dihydrotestosterone. Part I: concentrations and methods of determination in men with benign prostatic hyperplasia and prostate cancer : INTRAPROSTATIC ANDROGEN ASSESSMENT IN UNTREATED BPH AND PROSTATE CANCER
TM van der Sluis, AN Vis, RJ van Moorselaar, HN Bui, MA Blankenstein, EJ Meuleman, AC Heijboer |
BJU International | 2011 |
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
Modified Ferriman–Gallwey hirsutism score and androgen levels in Turkish women
A Coskun, O Ercan, DC Arikan, A Özer, M Kilinc, G Kiran, B Kostu |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2011 |
Androgens and estrogens in benign prostatic hyperplasia: past, present and future
TM Nicholson, WA Ricke |
Differentiation | 2011 |
Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues
S Arai, Y Miyashiro, Y Shibata, Y Tomaru, M Kobayashi, S Honma, K Suzuki |
Steroids | 2011 |
Temporary Placement of a Covered, Retrievable, Barbed Stent for the Treatment of Hormone-induced Benign Prostatic Hyperplasia: Technical Feasibility and Histologic Changes in Canine Prostates
CJ Yoon, HY Song, JH Kim, HG Park, HS Kang, JY Ro, JH Hong |
Journal of Vascular and Interventional Radiology | 2010 |
Vitamins & Hormones
KJ Hare, FK Knop |
Vitamins & Hormones | 2010 |
Benign Prostatic Hyperplasia
DR Paolone |
Clinics in Geriatric Medicine | 2010 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Benign Prostatic Hyperplasia and Its Aetiologies
A Briganti, U Capitanio, N Suardi, A Gallina, A Salonia, M Bianchi, M Tutolo, VD Girolamo, G Guazzoni, P Rigatti, F Montorsi |
European Urology Supplements | 2009 |
The Effect of Transarterial Prostate Embolization in Hormone-induced Benign Prostatic Hyperplasia in Dogs: A Pilot Study
GS Jeon, JH Won, BM Lee, JH Kim, HS Ahn, EJ Lee, SI Park, SW Park |
Journal of Vascular and Interventional Radiology | 2009 |
Validation of a testosterone and dihydrotestosterone liquid chromatography tandem mass spectrometry assay: Interference and comparison with established methods
C Wang, S Shiraishi, A Leung, S Baravarian, L Hull, V Goh, PW Lee, RS Swerdloff |
Steroids | 2008 |
Prostate Tissue Androgens: History and Current Clinical Relevance
LS Marks, EA Mostaghel, PS Nelson |
Urology | 2008 |
Canine prostatic disease: A review of anatomy, pathology, diagnosis, and treatment
J Smith |
Theriogenology | 2008 |
Encyclopedia of Molecular Cell Biology and Molecular Medicine
E Beutler |
Encyclopedia of Molecular Cell Biology and Molecular Medicine | 2006 |
New progesterone derivatives as inhibitors of 5α-reductase enzyme and prostate cancer cell growth
M Cabeza, E Bratoeff, I Heuze, A Rojas, N Terán, M Ochoa, MT Ramírez-Apan, E Ramírez, V Pérez, I Gracia |
Journal of Enzyme Inhibition and Medicinal Chemistry | 2006 |
PROSTATIC CANCER/BENIGN PROSTATIC HYPERTROPHY. SUBCELLULAR DISTRIBUTION OF ESTRADIOL/ANDROGEN RECEPTORS
EL Salazar, E Mercado, L Calzada |
Systems Biology in Reproductive Medicine | 2005 |
Postnatal Developmental Milestones
T Zoetis, M Tassinari, C Bagi, K Walthall, M Hurtt |
Developmental and Reproductive Toxicology A Practical Approach Second Edition | 2005 |
Reflecting on 80 years of excellence
U Savla |
Journal of Clinical Investigation | 2004 |
Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term daily oral administration to healthy young men
BD Acacio, FZ Stanczyk, P Mullin, P Saadat, N Jafarian, RZ Sokol |
Fertility and Sterility | 2004 |
Prooxidant and antioxidant action of 4-(4-phenoxybenzoyl)benzoic acid derivatives
HY Aboul-Enein, A Kladna, I Kruk, K Lichszteld, M Marchlewicz, T Michalska, OI Salem, RW Hartmann |
Biopolymers | 2004 |
Changing aspects in the evaluation and treatment of patients with benign prostatic hyperplasia
JS Lam, KL Cooper, SA Kaplan |
Medical Clinics of North America | 2004 |
Finasteride versus cyproterone acetate–estrogen regimens in the treatment of hirsutism
A Beigi, A Sobhi, F Zarrinkoub |
International Journal of Gynecology & Obstetrics | 2004 |
Benign prostate hyperplasia: evaluation of treatment response with DCE MRI
JT Heverhagen, H von Tengg-Kobligk, KT Baudendistel, G Jia, H Polzer, H Henry, AL Levine, TJ Rosol, MV Knopp |
Magma (New York, N.Y.) | 2004 |
Molekularmedizinische Grundlagen von altersspezifischen Erkrankungen
D Ganten, K Ruckpaul, A Ruiz-Torres |
2004 | |
A DOUBLELIFE: Academic Physician and Androgen Physiologist
JD Wilson |
Annual Review of Physiology | 2003 |
Androgens Up-Regulate Atherosclerosis-Related Genes in Macrophages From Males But Not Females
MK Ng, CM Quinn, JA McCrohon, S Nakhla, W Jessup, DJ Handelsman, DS Celermajer, AK Death |
Journal of the American College of Cardiology | 2003 |
Molecular Interactions of New Pregnenedione Derivatives
E Bratoeff, E Ramírez, E Flores, N Valencia, M Sánchez, I Heuze, M Cabeza |
CHEMICAL & PHARMACEUTICAL BULLETIN | 2003 |
Development and maturation of the male reproductive system
MS Marty, RE Chapin, LG Parks, BA Thorsrud |
Birth defects research. Part B, Developmental and reproductive toxicology | 2003 |
Phenolic Constituents from Dalbergiacochinchinensis
O Shirota, V Pathak, S Sekita, M Satake, Y Nagashima, Y Hirayama, Y Hakamata, T Hayashi |
Journal of Natural Products | 2003 |
A mission statement for the JCI at the dawn of the 21st Century
Andrew Marks |
Journal of Clinical Investigation | 2002 |
5α-Reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids
H Pham, VA Ziboh |
The Journal of Steroid Biochemistry and Molecular Biology | 2002 |
Androgens and Androgen Receptor
C Chang |
2002 | |
Structure of the Human 3α-Hydroxysteroid Dehydrogenase Type 3 in Complex with Testosterone and NADP at 1.25-Å Resolution
V Nahoum, A Gangloff, P Legrand, DW Zhu, L Cantin, BS Zhorov, V Luu-The, F Labrie, R Breton, SX Lin |
The Journal of biological chemistry | 2001 |
Immunolocalization of Androgen Receptor (AR) and Steroid 5 Alpha-Reductase Type II (5 Alpha-Reductase Type II) in Canine Prostate. Effect of Antiandrogen, Chlornradinone Acetate (CMA)
M Murakoshi, M Tagawa, R Ikeda, T Nakayama, K Ishimura |
ACTA HISTOCHEMICA ET CYTOCHEMICA | 2000 |
Partial sequencing and tissue distribution of the canine isoforms of steroid 5?-Reductase type I and type II
PN Span, A Bokhoven, AG Smals, CG Sweep, JA Schalken |
The Prostate | 2000 |
Benigne Prostatahyperplasie
K Höfner, U Jonas, CG Stief |
2000 | |
Comparative QSAR Analysis of 5α-Reductase Inhibitors
A Kurup, R Garg, C Hansch |
Chemical Reviews | 2000 |
Treatment of hirsutism: comparisons between different antiandrogens with central and peripheral effects
F Fruzzetti, C Bersi, D Parrini, C Ricci, AR Genazzani |
Fertility and Sterility | 1999 |
Presentation of the Kober Medal for 1999 to Jean D. Wilson Physician-Scientist Exemplar
JL Goldstein, MS Brown |
Proceedings of The Association of American Physicians | 1999 |
Efficacy of Various Natural and Synthetic Androgens to Induce Ductal Branching Morphogenesis in the Developing Anterior Rat Prostate**This work was supported by NIH Grants DK-45861, DK-52708, CA-64872, and CA-59831
BA Foster, GR Cunha |
Endocrinology | 1999 |
Effects of long-term treatment withSerenoa repens (Permixon®) on the concentrations and regional distribution of androgens and epidermal growth factor in benign prostatic hyperplasia
FD Silverio, S Monti, A Sciarra, PA Varasano, C Martini, S Lanzara, G D'Eramo, SD Nicola, V Toscano |
The Prostate | 1998 |
Pharmacokinetics and pharmacodynamics of FK143, a nonsteroidal inhibitor of steroid 5α-reductase, in healthy volunteers
M Katashima, T Irino, F Shimojo, A Kawamura, H Kageyama, N Higashi, Y Miyao, Y Tokuma, T Hata, K Yamamoto, Y Sawada, T Iga |
Clinical Pharmacology & Therapeutics | 1998 |
Identification and partial characterization of two steroid 5α-reductase isozymes in the canine prostate
PN Span, JA Schalken, FG Sweep, AG Smals |
The Prostate | 1998 |
Association of Benign Prostatic Hyperplasia with Male Pattern Baldness
BR Oh, SJ Kim, JD Moon, HN Kim, DD Kwon, YH Won, SB Ryu, YI Park |
Urology | 1998 |
Synthesis and 5α-reductase inhibitory activities of benzofuran derivatives with a carbamoyl group
K Ishibashi, K Nakajima, Y Sugioka, M Sugiyama, T Hamada, H Horikoshi, T Nishi |
Bioorganic & Medicinal Chemistry Letters | 1998 |
Antiandrogenic phenolic constituents from Dalbergia cochinchinensis
V Pathak, O Shirota, S Sekita, Y Hirayama, Y Hakamata, T Hayashi, T Yanagawa, M Satake |
Phytochemistry | 1997 |
The effects of progesterone, 4,16-androstadien-3-one and MK-434™ on the kinetics of pig testis microsomal testosterone-4-ene-5α-reductase activity
GM Cooke, F Pothier, BD Murphy |
The Journal of Steroid Biochemistry and Molecular Biology | 1997 |
Finasteride in biological fluids: extraction and separation by a graphitized carbon black cartridge and quantification by high-performance liquid chromatography
G Carlucci, P Mazzeo |
Journal of Chromatography B: Biomedical Sciences and Applications | 1997 |
Expression and Characterization of Recombinant Type 2 3α-Hydroxysteroid Dehydrogenase (HSD) from Human Prostate: Demonstration of Bifunctional 3α/17β-HSD Activity and Cellular Distribution
HK Lin, JM Jez, BP Schlegel, DM Peehl, JA Pachter, TM Penning |
Molecular Endocrinology | 1997 |
Antiandrogenic Natural Diels−Alder-Type Adducts from Brosimum rubescens
O Shirota, K Takizawa, S Sekita, M Satake, Y Hirayama, Y Hakamata, T Hayashi, T Yanagawa |
Journal of Natural Products | 1997 |
Age-dependent expression of the androgen receptor gene in the prostate and its implication in glandular differentiation and hyperplasia
GS Prins, MH Jung, RL Vellanoweth, B Chatterjee, AK Roy |
Developmental Genetics | 1996 |
Characterization of 5α-reductase gene expression in stroma and epithelium of human prostate
N Bruchovsky, MD Sadar, K Akakura, SL Goldenberg, K Matsuoka, PS Rennie |
The Journal of Steroid Biochemistry and Molecular Biology | 1996 |
Serenoa repens (Permixon®): A Review of its Pharmacology and Therapeutic Efficacy in Benign Prostatic Hyperplasia
GL Plosker, RN Brogden |
Drugs & Aging | 1996 |
Sex Steroids and Epidermal Growth Factor in Benign Prostatic Hyperplasia (BPH)
F Sciarra |
Annals of the New York Academy of Sciences | 1995 |
Synthesis and Biochemical Evaluation of (Carbamoylalkenyl)phenyloxy Carboxylic Acid Derivatives as Non-steroidal 5α-Reductase Inhibitors
L Kattner, S Göhring, RW Hartmann |
Archiv der Pharmazie | 1995 |
Pathogenesis and medical management of benign prostatic hyperplasia
AC Levine |
Trends in Endocrinology & Metabolism | 1995 |
Androgen, estrogen, and progesterone receptors in normal and aging prostates
G Srinivasan, E Campbell, N Bashirelahi |
Microscopy Research and Technique | 1995 |
The enzyme and inhibitors of 4-ene-3-oxosteroid 5α-oxidoreductase
X Li, C Chen, SM Singh, F Labire |
Steroids | 1995 |
Benign prostatic hyperplasia
WD Steers, B Zorn |
Disease-a-Month | 1995 |
Clinical and endocrine effects of finasteride, a 5α-reductase inhibitor, in women with idiopathic hirsutism
L Ciotta, A Cianci, AE Calogero, MA Palumbo, E Marletta, A Sciuto, G Palumbo |
Fertility and Sterility | 1995 |
5α-Reductase inhibitors and prostatic disease
FH Schröder |
Clinical Endocrinology | 1994 |
Synthesis of B-NOR-4-AZA-5α-androstane compound as 5α-reductase inhibitor
K Ishibashi, H Kurata, K Kojima, H Horikoshi |
Bioorganic & Medicinal Chemistry Letters | 1994 |
Picogram determination of finasteride in human plasma and semen by high-performance liquid chromatography with atmospheric-pressure chemical-ionization tandem mass spectrometry
ML Constanzer, CM Chavez, BK Matuszewski |
Journal of Chromatography B: Biomedical Sciences and Applications | 1994 |
Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression
AE Thigpen, RI Silver, JM Guileyardo, ML Casey, JD McConnell, DW Russell |
Journal of Clinical Investigation | 1993 |
Role of programmed cell death in carcinogenesis
JT Isaacs |
Environmental Health Perspectives | 1993 |
Direct quantitative digital autoradiography of testosterone metabolites in the pilosebaceous unit: an environmentally advantageous trace radioactive technology
P Vingler, H Filthuth, A Bague, F Pruche, M Kermici |
Steroids | 1993 |
Nephrology and Urology in the Aged Patient
DG Oreopoulos, MF Michelis, S Herschorn |
1993 | |
Determination of L-654,066, a new 5α-reductase inhibitor in plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry
JD Gilbert, TV Olah, A Barrish, TF Greber |
Biological Mass Spectrometry | 1992 |
Effects of the new steroidal antiandrogen TZP-4238 on hormone-induced canine prostatic hyperplasia
Y Takezawa, Y Fukabori, H Yamanaka, M Mieda, S Honma, M Kushitani, N Hamataki |
The Prostate | 1992 |
Finasteride in the Treatment of Benign Prostatic Hyperplasia. A Urodynamic Evaluation
RS Kirby, J Bryan, I Eardley, TJ Christmas, S Liu, SA Holmes, JA Vale, K Shanmuganathan, JA Webb |
British Journal of Urology | 1992 |
Benign prostatic hyperplasia: pathogenesis and the role of medical management
WJ Canovatchel, J Imperato-McGinley |
Geriatric Nephrology and Urology | 1992 |
In Vitro Studies on the Effect of Cofactors on the 5 α -Reductase and 3 α - and 3 β -hydroxysteroid Reductase Activities in the Hyperplastic Human Prostate
ME Lombardo, SI Hakky, MK Hall, PB Hudson |
The Journal of Urology | 1992 |
Androgen concentrations in expressed prostatic secretions: no correlation with tissue levels
FK Habib, CM Goodman, C Buck |
Urological Research | 1992 |
Review of current and future approaches to the management of benign prostatic hyperplasia
JC Gingell |
Postgraduate medical journal | 1992 |
Pharmacokinetics and biochemical efficacy after single and multiple oral administration of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a new type of specific competitive inhibitor of testosterone 5α-reductase, in volunteers
M Ohtawa, H Morikawa, J Shimazaki |
European Journal of Drug Metabolism and Pharmacokinetics | 1991 |
DNA flow cytometric study of the hyperplastic and neoplastic canine prostate
BR Madewell, AD Deitch, RJ Higgins, SL Marks, RW White |
The Prostate | 1991 |
Magnetic resonance imaging of the efficacy of specific inhibition of 5α-reductase in canine spontaneous benign prostatic hyperplasia
SM Cohen, KH Taber, PF Malatesta, J Shpungin, C Berman, JR Carlin, JG Werrmann, S Prahalada, RN Bryan, EH Cordes |
Magnetic Resonance in Medicine | 1991 |
Endocrine treatment of benign prostatichypertrophy: Current concepts
H Matzkin, Z Braf |
Urology | 1991 |
International Review of Cytology
RA Miller |
International Review of Cytology | 1991 |
Benign Prostatic Hyperplasia: Pathogenesis and Medical Therapy
J Geller |
Journal of the American Geriatrics Society | 1991 |
Prostates, Pates, and Pimples: The Potential Medical Uses of Steroid 5α-Reductase Inhibitors
JS Tenover |
Endocrinology and metabolism clinics of North America | 1991 |
Growth Factors in Reproduction
DW Schomberg |
1991 | |
Enzymes of Androgen Formation and Degradation in the Human Prostate
W Bartsch, H Klein, U Schiemann, HW Bauer, KD Voigt |
Annals of the New York Academy of Sciences | 1990 |
Steroid Metabolism and Binding in Relation to Prostatic Cell Growth and Differentiation in Vitro
S Chevalier, G Turcotte, G McKercher, P Boulanger, A Chapdelaine |
Annals of the New York Academy of Sciences | 1990 |
Comparison of the nuclear 5α-reduction of testosterone and androstenedione in human prostatic carcinoma and benign prostatic hyperplasia
RW Hudson, D Wherrett |
Journal of Steroid Biochemistry | 1990 |
Das Prostatakarzinom
G Staehler, PG Fabricius |
1990 | |
Clinical and Experimental Studies of Benign Prostatic Hyperplasia
DS Coffey, PC Walsh |
The Urologic clinics of North America | 1990 |
Etiology and disease process of benign prostatic hyperplasia
JT Isaacs, DS Coffey |
The Prostate | 1989 |
Pathogenesis and medical treatment of benign prostatic hyperplasia
J Geller |
The Prostate | 1989 |
Overview of benign prostatic hypertrophy
J Geller |
Urology | 1989 |
Alpha-adrenoceptor inhibitors in the treatment of benign prostatic hyperplasia
RS Kirby |
The American Journal of Medicine | 1989 |
Enzymes As Targets for Drug Design
MB Murphy, AS Bass, LI Goldberg |
Enzymes As Targets for Drug Design | 1989 |
Novel methods of oestrogen deprivation for treatment of breast diseases
RJ Santen |
Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences | 1989 |
Antiandrogenic treatment of benign prostatic hyperplasia: a placebo controlled trial
P Ostri, R Swartz, HH Meyhoff, JH Petersen, G Lindgrd, C Frimodt-Mller, T Andersson, MS Nielsen |
Urological Research | 1989 |
Vitamin D
A Portale, Β Halloran, E Lonergan, R Morris |
Vitamin D | 1988 |
Androgen binding as evidenced by a whole cell assay system using cultured canine prostatic epithelial cells
G Turcotte, A Chapdelaine, KD Roberts, S Chevalier |
Journal of Steroid Biochemistry | 1988 |
High-performance liquid chromatographic determination of N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide, a 4-azasteroid, in human plasma from a phase I study
JR Carlin, P Christofalo, WJ Vandenheuvel |
Journal of Chromatography B Biomedical Sciences and Applications | 1988 |
Androgen Concentration in Blacks with Benign and Malignant Prostatic Disease
DN Osegbe, JO Ogunlewe |
The Journal of Urology | 1988 |
Comparative study of plasma steroid and steroid glucuronide levels in normal men and in men with benign prostatic hyperplasia
M Brochu, A Bélanger |
The Prostate | 1987 |
Transplantable human prostatic carcinoma (PC-82) in athymic nude mice: I. Hormone dependence and the concentration of androgens in plasma and tumor tissue
GJ van Steenbrugge, JJ van Dongen, PJ Reuvers, FH de Jong, FH Schroeder |
The Prostate | 1987 |
Dihydrotestosterone does not induce prostate adenocarcinoma in L-W rats
M Pollard, DL Snyder, PH Luckert |
The Prostate | 1987 |
Induction of estrogen-related hyperplastic changes in the prostate of the cynomolgus monkey (Macaca fascicularis) by androstenedione and its antagonization by the aromatase inhibitor 1-methyl-androsta-1,4-diene-3,17-dione
UF Habenicht, K Schwarz, F Neumann, MF el Etreby |
The Prostate | 1987 |
Estrogens and benign prostatic hyperplasia: The basis for aromatase inhibitor therapy
D Henderson, UF Habenicht, Y Nishino, MF Etreby |
Steroids | 1987 |
Comparison of nuclear 5α-reductase activities in the stromal and epithelial fractions of human prostatic tissue
RW Hudson |
Journal of Steroid Biochemistry | 1987 |
The possibility of aromatization of androgen in human prostate
Y Kaburagi, MB Marino, RY Kirdani, JP Greco, JP Karr, AA Sandberg |
Journal of Steroid Biochemistry | 1987 |
Correlation of Biochemical (Receptors, Endogenous Tissue Hormones) and Quantitative Morphologic (Stereologic) Findings in Normal and hyperplastic Human Prostates
G Bartsch, F Keen, G Daxenbichler, C Marth, R Margreiter, A Brüngger, T Sutter, HP Rohr |
The Journal of Urology | 1987 |
Characterization of androgen receptors in normal and malignant human prostatic tissues
F Radwan, F Léger, JG Lehoux, M Carmel, M Elhilali |
The Prostate | 1986 |
Concentrations of androgens in human benign prostatic hypertrophic tissues incubated for up to three days
NJ Bolton, R Vihko, O Lukkarinen |
The Prostate | 1986 |
Regional variation of cytosol androgen receptors throughout the diseased human prostate gland
SP Bowman, DM Barnes, NJ Blacklock, PJ Sullivan |
The Prostate | 1986 |
Association states of androgen receptors in nuclei of human benign hypertrophic prostate
N Kyprianou, P Davies |
The Prostate | 1986 |
Development of a model for the induction of estrogen-related prostatic hyperplasia in the dog and its response to the aromatase inhibitor 4-hydroxy-4-androstene-3,17-dione: Preliminary results
UF Habenicht, K Schwarz, HU Schweikert, F Neumann, ME Etreby |
The Prostate | 1986 |
Concentrations of 3β-hydroxy androgens in epithelium and stroma of benign hyperplastic and normal human prostate
W Bartsch, I Kozák, P Gorenflos, H Becker, KD Voigt |
The Prostate | 1986 |
Androgen-Binding Proteins from Human Hyperplastic Prostate as Evaluated by Electrophoresis
E Barahona, H Licea, F Torres, J Sierra, S Ortiz, JA Bermudez |
Systems Biology in Reproductive Medicine | 1986 |
Prostatic effects induced in dogs by chronic or acute oral administration of 5α-reductase inhibitors
JR Brooks, C Berman, D Garnes, D Giltinan, PF Malatesta, RL Primka, GF Reynolds, GH Rasmusson, LR Gordon |
The Prostate | 1986 |
Dihydrotestosterone and 3α-androstanediol dynamics in the normal, involuted, and hyperplastic canine prostate
G McKercher, S Chevalier, KD Roberts, G Bleau, A Chapdelaine |
Steroids | 1986 |
3 Changing concepts of active androgens in blood
PK Siiteri, NH Simberg |
Clinics in Endocrinology and Metabolism | 1986 |
In vitro metabolism of testosterone in the rat prostate: Influence of aging
M Motta, S Zoppi, L Martini |
Journal of Steroid Biochemistry | 1986 |
Intratissular androgens in benign prostatic hyperplasia and prostatic cancer
KD Voigt, W Bartsch |
Journal of Steroid Biochemistry | 1986 |
Preponderance of serum and intra-hepatic 5α-dihydrotestosterone in males with hepatocellular carcinoma despite low circulating androgen levels
MJ Iqbal, ML Wilkinson, A Forbes, TP Corbishley, R Williams |
Journal of Hepatology | 1986 |
5α-Reductase inhibitory and anti-androgenic activities of some 4-azasteroids in the rat
JR Brooks, C Berman, RL Primka, GF Reynolds, GH Rasmusson |
Steroids | 1986 |
The effects of diethyl-4-methyl-3-oxo-4-aza-5α-androstane-17β-carboxamide (4-ma) and (4r)-5,10-SECO-19-norpregna-4,5-diene-3,10,20-trione (SECO) on androgen biosynthesis in the rat testis and epididymis
GM Cooke, B Robaire |
Journal of Steroid Biochemistry | 1986 |
L'Estratto Di Serenoa Repens Nell'Iperplasia Prostatica
D Minocci, G Monesi, G Pretti |
1986 | |
5α-REDUCTASE ACTIVITY IN HUMAN PROSTATE CANCER IS RELATED TO THE HISTOLOGICAL DIFFERENTIATION OF THE TUMOUR
FK Habib, A Busuttil, RA Robinson, GD Chisholm |
Clinical Endocrinology | 1985 |
Tissue interactions and prostatic growth: II. Morphological and biochemical characterization of adult mouse prostatic hyperplasia induced by fetal urogenital sinus implants
GJ Miller, MN Runner, LW Chung |
The Prostate | 1985 |
Sex steroid receptors in normal and hyperplastic human prostate
P Robel, B Eychenne, JP Blondeau, EE Baulieu, O Hechter |
The Prostate | 1985 |
The effect of 5α-androstane-3α, 17β-diol and 17β-estradiol on the adult and immature chacma baboon prostate
DP de Klerk, HJ Human, JN de Klerk |
The Prostate | 1985 |
Hormonal aspects of prostatic cancer: a review
J Waxman |
Journal of the Royal Society of Medicine | 1985 |
Quantification of cytosolic steroid receptors in secretory and non-secretory epithelial cells of the canine prostate
D Lamarre, S Chevalier, G McKercher, G Bleau, KD Roberts, A Chapdelaine |
Journal of Steroid Biochemistry | 1985 |
The prostasome: its secretion and function in man
G Ronquist, I Brody |
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes | 1985 |
Hydroxylation of [3h]5α-androstane-3β,17β-diol by whole tissue, epithelial cells and fibroblasts from the same hyperplastic human prostate
P Ofner, WH Douglas, SD Spilman, RL Vena, P Krinsky-Feibush, PW LeQuesne |
Journal of Steroid Biochemistry | 1985 |
Biochemical Actions of Hormones
D Marver |
Biochemical Actions of Hormones | 1985 |
A new dihydrotestosterone-forming index (DHTi)
PI Lundmo, A Sunde, KJ Tveter |
Journal of Steroid Biochemistry | 1985 |
Correlated Biochemical and Stereological Studies on Testosterone Metabolism in the Stromal and Epithelial Compartment of Human Benign Prostatic Hyperplasia
HU Schweikert, P Totzauer, HP Rohr, G Bartsch |
The Journal of Urology | 1985 |
The Effect of Testicular Irradiation on Established BPH in the Dog: Evidence of a Non-Steroidal Testicular Factor for BPH Maintenance
JT Grayhack, C Lee, W Brand |
The Journal of Urology | 1985 |
Discrimination between Normal, Hyperplastic and Malignant Human Prostatic Tissues by Enzymatic Profiles
CB Brendler, AL Follansbee, JT Isaacs |
The Journal of Urology | 1985 |
Mitogenic Factors in Prostatic Tissue and Expressed Prostatic Secretion
RE Tackett, WD Heston, RF Parrish, LS Pletscher, WR Fair |
The Journal of Urology | 1985 |
Studies on the role of sex-hormone-binding globulin (SHBG) in benign prostatic hypertrophy in men
A Pachman |
International Urology and Nephrology | 1984 |
Physicochemical characterization of the androgen receptor from hyperplastic human prostate
LR Murthy, CH Chang, DR Rowley, PT Scardino, DJ Tindall |
The Prostate | 1984 |
The articulations of Adam's rib with the lower urinary tract
DD Federman |
Kidney International | 1984 |
Nonsteroidal serum factors involved in the regulation of the proliferation of canine prostatic epithelial cells in culture
S Chevalier, G Bleau, KD Roberts, A Chapdelaine |
The Prostate | 1984 |
A double-blind trial of an extract of the plant Serenoa repens in benign prostatic hyperplasia
G Champault, JC Patel, AM Bonnard |
British Journal of Clinical Pharmacology | 1984 |
Induction of benign prostatichypertrophy in baboons
JP Karr, U Kim, JA Resko, S Schneider, LS Chai, GP Murphy, AA Sandberg |
Urology | 1984 |
[1-14C]acetate incorporation into free and esterified cholesterol during the development of the rat ventral prostate
MJ Carmena, MA Perez-Albarsanz, MN Recio |
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry | 1984 |
5α-reductase and 3α-hydroxysteroid dehydrogenase activities in isolated canine prostatic epithelial cells
G McKercher, S Chevalier, KD Roberts, G Bleau, A Chapdelaine |
Journal of Steroid Biochemistry | 1984 |
Binding of permixon, a new treatment for prostatic benign hyperplasia, to the cytosolic androgen receptor in the rat prostate
E Carilla, M Briley, F Fauran, C Sultan, C Duvilliers |
Journal of Steroid Biochemistry | 1984 |
Novel Approaches to Cancer Chemotherapy
V Petrow, GM Padilla |
Novel Approaches to Cancer Chemotherapy | 1984 |
Androgenic control of acetate incorporation into phospholipids and triacylglycerols in rat ventral prostate
N Hoyo, LA Torre, MA Pérez-Albarsanz |
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry | 1984 |
Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in the Male
R Horton |
Journal of the American Geriatrics Society | 1984 |
Geriatrics 3
D Platt |
1984 | |
4-Azasteroidal 5 alpha-reductase inhibitors without affinity for the androgen receptor
T Liang, CE Heiss, AH Cheung, GF Reynolds, GH Rasmusson |
The Journal of biological chemistry | 1984 |
Studies on the role of sex-hormone-binding globulin (SHBG) in benign prostatic hypertrophy in men: I. Clinical research
A Pachman |
International Urology and Nephrology | 1984 |
Spontaneous benign prostatic hyperplasia in the beagle. Age-associated changes in serum hormone levels, and the morphology and secretory function of the canine prostate
CB Brendler, SJ Berry, LL Ewing, AR McCullough, RC Cochran, JD Strandberg, BR Zirkin, DS Coffey, LG Wheaton, ML Hiler, MJ Bordy, GD Niswender, WW Scott, PC Walsh |
Journal of Clinical Investigation | 1983 |
Tissue content of dihydrotestosterone in human prostatic hyperplasis is not supranormal
PC Walsh, GM Hutchins, LL Ewing |
Journal of Clinical Investigation | 1983 |
Nuclear androgen receptors in the epithelium and stroma of human benign prostatic hypertrophic glands
R Lahtonen, NJ Bolton, R Vihko, M Kontturi |
The Prostate | 1983 |
Changes in dihydrotestosterone metabolism and the development of benign prostatic hyperplasia in the aging beagle
JT Isaacs |
Journal of Steroid Biochemistry | 1983 |
Biochemical and biological studies with 4-aza-steroidal 5α-reductase inhibitors
T Liang, GH Rasmusson, JR Brooks |
Journal of Steroid Biochemistry | 1983 |
Kinetic analysis of 5α-reductase isoenzymes in benign prostatic hyperplasia (BPH)
PS Rennie, N Bruchovsky, MG McLoughlin, FH Batzold, EE Dunstan-Adams |
Journal of Steroid Biochemistry | 1983 |
Androgens and estrogens: Their interaction with stroma and epithelium of human benign prostatic hyperplasia and normal prostate
M Krieg, W Bartsch, M Thomsen, KD Voigt |
Journal of Steroid Biochemistry | 1983 |
Epidermal Growth Factor is not the Major Growth-Promoting Agent in Extracts of Prostatic Tissue
MT Story, SC Jacobs, RK Lawson |
The Journal of Urology | 1983 |
Benign Prostatic Hypertrophy
F Hinman, S Boyarsky |
1983 | |
The clinical significance of steroid hormone measurements in the management of patients with prostatic cancer
R Ghanadian, CM Puah |
World Journal of Urology | 1983 |
Cancer of the Prostate and Kidney
M Pavone-Macaluso, PH Smith |
1983 | |
Gene Regulation by Steroid Hormones II
AK Roy, JH Clark |
1983 | |
Effect of a new 5α-reductase inhibitor on size, histologic characteristics, and androgen concentrations of the canine prostate
JR Brooks, D Berman, MS Glitzer, LR Gordon, RL Primka, GF Reynolds, GH Rasmusson |
The Prostate | 1982 |
Testosterone metabolism by homogenates of human prostates with benign hyperplasia: Effect of tissular concentrations of zinc, magnesium and copper
G Sinquin, R Morfin, JF Charles, HH Floch |
Journal of Steroid Biochemistry | 1982 |
Effect of hormone injections on levels of cytosolic receptors for estrogen, androgen and progesterone in dog prostate
G Frenette, JY Dube, RR Tremblay |
Journal of Steroid Biochemistry | 1982 |
Effects of the administration of androgenic and estrogenic steroids on 3α-hydroxysteroid dehydrogenase levels of the intact and castrated dog prostate
P Talalay, M Shikita, M Renaud |
Journal of Steroid Biochemistry | 1982 |
Studies of the cytosol 3α-hydroxysteroid dehydrogenase of human prostatic tissue: Comparison of enzyme activities in hyperplastic, malignant and normal tissues
RW Hudson |
Journal of Steroid Biochemistry | 1982 |
Uptake and retention of androgens by the rat ventral prostate and consideration of their use as site directing agents
EK Symes |
Biochemical Pharmacology | 1982 |
Plasma steroids in benign prostatic hypertrophy and carcinoma of the prostate
D Drafta, E Proca, V Zamfir, AE Schindler, E Neacsu, E Stroe |
Journal of Steroid Biochemistry | 1982 |
Preparation of Epithelial and Stromal Cell Fractions from Immature Rat Prostatic Tissue Using Percoll Gradients
J Orlowski, CE Bird, AF Clark |
Journal of andrology | 1982 |
Testosterone Metabolism of Fibroblasts Grown From Prostatic Carcinoma, Benign Prostatic Hyperplasia and Skin Fibroblasts
HU Schweikert, HJ Hein, JC Romijn, FH Schröder |
The Journal of Urology | 1982 |
The Endocrinology of Prostate Tumours
R Ghanadian |
1982 | |
Enzymatic estimation of steroids in subpicomole quantities by hydroxysteroid dehydrogenases and nicotinamide nucleotide cycling
DW Payne, M Shikita, P Talalay |
The Journal of biological chemistry | 1982 |
Suppressive Effects of Surgical Stress on Circulating Androgens During and After Prostatectomy
R Ghanadian, CM Puah, G Williams, PJ Shah, N McWHlNNEY |
British Journal of Urology | 1981 |
Inhibition of Testosterone Metabolism by Medrogestone in Rat Ventral Prostate in Vivo and in Vitro
N Jagarinec, ML Givner |
Systems Biology in Reproductive Medicine | 1981 |
Responses of serum levels of testicular steroid hormones to hCG stimulation in patients with prostatic cancer and benign prostatic hypertrophy
K Isurugi, M Kanazawa, T Yanaihara, A Kambegawa |
The Prostate | 1981 |
Elevated intranuclear dihydrotestosterone in prostatic hyperplasia of aging dogs
AW Meikle, ES Collier, JD Stringham, SM Fang, GN Taylor |
Journal of Steroid Biochemistry | 1981 |
Studies of the nuclear 5α-reductase of human hyperplastic prostatic tissue
RW Hudson |
Journal of Steroid Biochemistry | 1981 |
Inhibition of 5 alpha-reductase, receptor binding, and nuclear uptake of androgens in the prostate by a 4-methyl-4-aza-steroid
T Liang, CE Heiss |
The Journal of biological chemistry | 1981 |
Stereological analysis of the dog prostate (analytical model)
HP Rohr, I Krisl, O Holliger, M Oberholzer, G Bartsch |
Urological Research | 1981 |
Androgen- and Estrogen-Receptor Content in Spontaneous and Experimentally Induced Canine Prostatic Hyperplasia
J Trachtenberg, LL Hicks, PC Walsh |
Journal of Clinical Investigation | 1980 |
Alteration in the metabolism of dihydrotestosterone in elderly men with prostate hyperplasia
I Morimoto, A Edmiston, R Horton |
Journal of Clinical Investigation | 1980 |
Dihydrotestosterone Receptors in the Human Prostate. I. Nuclear Concentration in Normal, Benign, and Malignant Tissues
JG Lehoux, B Benard, M Elhilali |
Systems Biology in Reproductive Medicine | 1980 |
Endocrine control and physiology of the prostate
AA Sandberg |
The Prostate | 1980 |
The effect of therapy on the concentration and occupancy of androgen receptors in human prostatic cytosol
BG Mobbs, IE Johnson, JG Connolly |
The Prostate | 1980 |
Peripheral and Prostatic Vein Steroid Concentrations in Benign Prostatic Hypertrophy Patients Before and After Removal of the Adenoma
O Lukkarinen, GL Hammond, M Kontturi, R Vihko |
Scandinavian Journal of Urology and Nephrology | 1980 |
Characterization of canine prostatic cells from normal and hyperplastic glands
S Chevalier, G Bleau, KD Roberts, A Chapdelaine |
Molecular and Cellular Endocrinology | 1980 |
Correlation between clinical response to antiandrogenic therapy and occurrence of receptors in human prostatic cancer
A Martelli, S Grilli, M Soli, CD Giovanni, E Bercovich, MC Galli, G Prodi |
Urology | 1980 |
The pathogenesis of benign prostatic hyperplasia
JD Wilson |
The American Journal of Medicine | 1980 |
Prostatic tissue distribution of 17β-hydroxy-5α-androstan-3-one and of androgen receptors in benign hyperplasia
DA Sirett, SK Cowan, AE Janeczko, JK Grant, ES Glen |
Journal of Steroid Biochemistry | 1980 |
Subcellular distribution of androgens in hyperplastic human prostate
L Verdonck, JP Slypere, MA Sayed, MV Sande, KV Camp, A Vermeulen |
Journal of Steroid Biochemistry | 1980 |
Prostatic Carcinoma
ES Hafez, E Spring-Mills |
1980 | |
Regulation of cytoplasmic dihydrotestosterone binding in dog prostate by 17 beta-estradiol
RJ Moore, JM Gazak, JD Wilson |
Journal of Clinical Investigation | 1979 |
Comparison of spontaneous and experimentally induced canine prostatic hyperplasia
DP DeKlerk, DS Coffey, LL Ewing, IR McDermott, WG Reiner, CH Robinson, WW Scott, JD Strandberg, P Talalay, PC Walsh, LG Wheaton, BR Zirkin |
Journal of Clinical Investigation | 1979 |
Concentration of Dihydrotestosterone and 3α-Androstanediol in Naturally Occurring and Androgen- Induced Prostatic Hyperplasia in the Dog
RJ Moore, JM Gazak, JF Quebbeman, JD Wilson |
Journal of Clinical Investigation | 1979 |
THE HORMONAL STATUS OF PATIENTS WITH BENIGN PROSTATIC HYPERTROPHY: FSH, LH, TSH AND PROLACTIN RESPONSES TO RELEASING HORMONES
GL Hammond, O Lukkarinen, P Vihko, M Kontturi, R Vihko |
Clinical Endocrinology | 1979 |
A Morphological Study on the Effect of Cyproterone Acetate on Human Prostatic Carcinoma
KJ Tveter, A Attramada, R Hannestad, B Otnes |
Scandinavian Journal of Urology and Nephrology | 1979 |
Serum testosterone and dihydrotestosterone in carcinoma of the prostate
R Ghanadian, CM Puah, EP O'Donoghue |
British Journal of Cancer | 1979 |
Benign prostatic hyperplasia in an XX man
MJ Marinello, W Montes, WE Farnsworth, D Hare, B Fisher, RM Bannerman |
Urology | 1979 |
Content of 5α-reduced androgens in subcellular compartments of dog prostate
AW Meikle, GV Burton, JD Stringham, F Sen-Maw |
Journal of Steroid Biochemistry | 1979 |
A comparative study of binding, metabolism and endogenous levels of androgens in normal, hyperplastic and carcinomatous human prostate
M Krieg, W Bartsch, W Janssen, KD Voigt |
Journal of Steroid Biochemistry | 1979 |
Binding of androgens in dog prostate cytosol and in plasma
JY Dubé, RR Tremblay, FT Dionne, P Chapdelaine |
Journal of Steroid Biochemistry | 1979 |
9 Ageing and endocrine function
PJ Davis |
Clinics in Endocrinology and Metabolism | 1979 |
Hormonal Steroids
W Nowaczynski, P Landais, T Murakami, M Nowaczynski, D Mavoungou, B Vitullo |
Hormonal Steroids | 1979 |
A microassay for the measurement of androgen receptors in human prostatic tissue
LL Hicks, PC Walsh |
Steroids | 1979 |
Testosterone 5α-reductase and the accumulation of dihydrotestosterone in benign prostatic hyperplasia
RA Cowan, BC Sheila, K Cowan, JK Grant, DA Sirett, AM wallace |
Journal of Steroid Biochemistry | 1979 |
C19O2-steroid transformations in the human normal, hyperplastic and cancerous prostate
RF Morfin, JF Charles, HH Floch |
Journal of Steroid Biochemistry | 1979 |
Metabolism of C19-radiosteroids by explants of canine prostate and epididymis with disposition as hydroxylated products: A possible mechanism for androgen inactivation
P Ofner, RL Vena, I Leav, DW Hamilton |
Journal of Steroid Biochemistry | 1979 |
3-Alpha-Androstanediol and Prostatic Growth: Comparison of 3-Alpha-Androstanediol Formation in Prostates from 8 Species Including Man and Dog
GH Jacobi, JD Wilson |
The Journal of Urology | 1979 |
Characterization of the Binding of a Potent Synthetic Androgen, Methyltrienolone, to Human Tissues
M Menon, CE Tananis, LL Hicks, EF Hawkins, MG McLoughlin, PC Walsh |
Journal of Clinical Investigation | 1978 |
Androgen Receptor Content of the Normal and Hyperplastic Canine Prostate
SA Shain, RW Boesel |
Journal of Clinical Investigation | 1978 |
Sex Steroid Production and Secretion in the Male*,**
R Horton |
Andrologia | 1978 |
SERUM STEROIDS IN NORMAL MALES AND PATIENTS WITH PROSTATIC DISEASES
GL Hammond, M Kontturi, P Vihko, R Vihko |
Clinical Endocrinology | 1978 |
The influence of aging on androgen dynamics in the male rat
CL Robinette, MG Mawhinney |
Archives of Biochemistry and Biophysics | 1978 |
Estrophilic molecules in the male guinea pig
CD Blume, MG Mawhinney |
Journal of Steroid Biochemistry | 1978 |
Comparison of testosterone, 5α-dihydrotestosterone and 5α-androstane-3β,17β-diol metabolisms in human normal and hyperplastic prostates
RF Morfin, SD Stefano, JP Bercovici, HH Floch |
Journal of Steroid Biochemistry | 1978 |
The use of methyltrienolone in the measurement of the free and bound cytoplasmic receptors for dihydrotestosterone in benign hypertrophied human prostate
R Ghanadian, G Auf, PJ Chaloner, GD Chisholm |
Journal of Steroid Biochemistry | 1978 |
Altered Androgen Metabolism in Metastatic Prostate Cancer
B Kliman, GR Prout, RA Maclaughlin, JJ Daly, PP Griffin |
The Journal of Urology | 1978 |
The Nuclear Uptake of Androgen by Human Benign Prostate in Vitro: Action of Antiandrogens
EK Symes, EJ Milroy, WI Mainwaring |
The Journal of Urology | 1978 |
Pharmacological Intervention in the Aging Process
J Roberts, RC Adelman, VJ Cristofalo |
1978 | |
SERUM FSH, LH AND PROLACTIN IN NORMAL MALES AND PATIENTS WITH PROSTATIC DISEASES
GL Hammond, M Kontturi, P Määttälä, M Puukka, R Vihko |
Clinical Endocrinology | 1977 |
β-retinoic acid inhibits and reverses testosterone-induced hyperplasia in mouse prostate organ cultures
DP Chopra, LJ Wilkoff |
Nature | 1977 |
Steroid receptors in the human prostate. Detection of tissue-specific androgen binding in prostate cancer
EF Hawkins, M Nijs, C Brassinne |
Clinica Chimica Acta | 1977 |
Serum Dihydrotestosterone in Patients with Benign Prostatic Hypertrophy
R Ghanadian, JG Lewis, GD Chisholm, EP O'donoghue |
British Journal of Urology | 1977 |
Metabolism of Testosterone in the Human Prostate and Seminal Vesicles
O Djøseland, KJ Tveter, A Attramadal, V Hansson, HN Haugen, W Mathisen |
Scandinavian Journal of Urology and Nephrology | 1977 |
Biosynthesis of [1,2-3H]5α-androstane-3β,7α,17β-triol
RF Morfin, S Stefano, LG Bardou, HH Floch |
Biochimie | 1977 |
Treatment of benign prostatic hyperplasia with hydroxyprogesterone-caproate placebo-controlled study
D Meiraz, Y Margolin, A Lev-Ran, J Lazebnik |
Urology | 1977 |
Ultrastructural and Enzyme-histochemical Studies of the Prostate of the Dog under the Effect of Estradiol
C Hohbach |
Beiträge zur Pathologie | 1977 |
Metabolism of 5α-dihydrotestosterone in human benign hyperplastic prostate
K Malathi, E Gurpide |
Journal of Steroid Biochemistry | 1977 |
Quantification of endogenous testosterone and dihydrotestosterone and their possible intracellular determinants in various tissues of the male guinea pig
FL Schwartz, MG Mawhinney |
Journal of Steroid Biochemistry | 1977 |
The Measurement of Androgen Receptors in Human Prostatic Tissue Utilizing Sucrose Density Centrifugation and a Protamine Precipitation Assay
M Menon, CE Tananis, MG Mcloughlin, ME Lippman, PC Walsh |
The Journal of Urology | 1977 |
The induction of prostatic hypertrophy in the dog with androstanediol
PC Walsh, JD Wilson |
Journal of Clinical Investigation | 1976 |
Influence of steroid-receptor complexes on transcription by human hypertrophied prostatic RNA polymerases
P Davies, K Griffiths |
Molecular and Cellular Endocrinology | 1976 |
Testosterone Metabolism in Benign Prostatic Hypertrophy:in vivoStudies of Gestonorone Caproate and Cyproterone Acetate
F Orestano, JE Altwein |
British Journal of Urology | 1976 |
A method for tissue extraction and determination of prostate concentrations of endogenous androgens by radioimmunoassay
J Albert, J Geller, S Geller, D Lopez |
Journal of Immunological Methods | 1976 |
Male pseudohermaphroditism: The complexities of male phenotypic development
J Imperato-McGinley, RE Peterson |
The American Journal of Medicine | 1976 |
Proceedings of the Fourth International Congress on Hormonal Steroids
RK Kalkhoff |
Proceedings of the Fourth International Congress on Hormonal Steroids | 1976 |
Mechanism of Action of the Sex Steroid Hormones
L Chan, BW O'Malley |
New England Journal of Medicine | 1976 |
Prostate concentrations of endogenous androgens by radioimmunoassay
J Albert, J Geller, S Geller, D Lopez |
Journal of Steroid Biochemistry | 1976 |
Urinary hormone excretion in benign prostatic hyperplasia
H Sko¨ldefs, K Carlstro¨m, M Furuhjelm |
Journal of Steroid Biochemistry | 1976 |
Intracellular localisation of 5α-dihydrotestosterone in human benign prostatic hypertrophy
R Ghanadian, GD Chisholm, K Fotherby |
Clinica Chimica Acta | 1976 |
Enzyme Induction
TD Gelehrter |
New England Journal of Medicine | 1976 |
Androgen of the Human Prostate
WE Farnsworth, JR Brown |
Endocrine Research | 1976 |
In Vitro Uptake of 3 H Testosterone and its Conversion to Dihydrotestosterone by Prostatic Carcinoma and Other Tissues
GR Prout, B Kliman, JJ Daly, RA Maclaughlin, PP Griffin |
The Journal of Urology | 1976 |
Steroid Hormone Action and Cancer
KM Menon, JR Reel |
1976 | |
Studies on the regulation of the concentration of androgens and androgen receptors in nuclei of prostatic cells
N Bruchovsky, PS Rennie, A Vanson |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 1975 |
Thin-layer chromatography and high resolution selected ion monitoring for the analysis of C19 steroids in human hyperplastic prostate tissue
DS Millington, ME Buoy, G Brooks, ME Harper, K Griffiths |
Biological Mass Spectrometry | 1975 |
Similarities between 5α-dihydrotestosterone-receptor complexes from human and rat prostatic tissue: Effects on RNA polymerase activity
P Davies, K Griffiths |
Molecular and Cellular Endocrinology | 1975 |
The effect of steroid hormones on the growth pattern and RNA synthesis in human benign prostatic hyperplasia in organ culture
I Lasnitzki, RH Whitaker, JF Withycombe |
British Journal of Cancer | 1975 |
Androgen receptor in human skin fibroblasts characterization of a specific 17β-hydroxy-5α-androstan-3-one-protein complex in cell sonicates and nuclei
BS Keenan, WJ Meyer, AJ Hadjian, CJ Migeon |
Steroids | 1975 |
The effect of a synthetic progestine on the fine structure of rat prostate (ultrastructural-morphometric analysis)
G Bartsch, C Hindermann, HP Rohr |
Experimental and Molecular Pathology | 1975 |
Androgen metabolism in the hypertrophic prostate
JD Wilson, RE Gloyna, PK Siiteri |
Journal of Steroid Biochemistry | 1975 |
Mechanism of androgen action at the cellular level
M Sluyser, AA Kassenaar |
Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology | 1975 |
Mode of action of progesterone, gestonorone capronate (depostat) and cyproterone acetate (androcur) on the metabolism of testosterone in human prostatic adenoma: in vitro and in vivo investigations
F Orestano, JE Altwein, P Knapsten, K Bandhauer |
Journal of Steroid Biochemistry | 1975 |
Testosterene and perogsterone metabolism and their interaction in the human hyperplastic prostate
RF Morfin, JP Bercovici, JF Charles, HH Floch |
Journal of Steroid Biochemistry | 1975 |
The influence of androgen receptors on the concentration of androgens in nuclei of hormone-responsive cells
N Bruchovsky, PS Rennie, B Lesser, DJ Sutherland |
Journal of Steroid Biochemistry | 1975 |
Properties and subcellular distribution of Δ4 -steroid (progesterone) 5α-reductase in rat anterior pituitary
C Yi-Juang, HJ Karavolas |
Steroids | 1975 |
Recent Advances in Steroid Biochemistry
O Domínguez, C Loza, L Morán, A Valencia |
1975 | |
Physiologic Basis for Hormonal Therapy in Carcinoma of the Prostate
PC Walsh |
The Urologic clinics of North America | 1975 |
Subcellular distribution and properties of progesterone (delta4-steroid) 5alpha-reductase in rat medial basal hypothalamus
YJ Cheng, HJ Karavolas |
The Journal of biological chemistry | 1975 |
A systematic study of testosterone metabolism in benign prostatic hypertrophy (BPH): In vitro results
JE Altwein, F Orestano |
Urological Research | 1975 |
In vitro studies of the regulation of androgen-tissue relationship in normal canine and hyperplastic human prostate
EP Giorgi, TF Moses, JK Grant, R Scott, J Sinclair |
Molecular and Cellular Endocrinology | 1974 |
The effects of 5alpha-dihydrotestosterone on the kinetics of cell proliferation in rat prostate
B Lesser, N Bruchovsky |
Biochemical Journal | 1974 |
Investigations of androgen-prostatic tissue relationships in superfusion experiments using steroid concentrations approaching those found in vivo
JK Grant, EP Giorgi |
Journal of Steroid Biochemistry | 1974 |
Studies on the in vivo hormonal control of rat prostatic testosterone 4-ene-5α-reductase activity
DK Lee, CE Bird, AF Clark |
Journal of Steroid Biochemistry | 1974 |
Current Topics in Experimental Endocrinology
M Jutisz, C Tertrin-Clary |
Current Topics in Experimental Endocrinology | 1974 |
Steroid–Cell Interactions
R King, W Mainwaring |
Steroid–Cell Interactions | 1974 |
Male Accessory Sex Organs
D Kirchheim, D Brandes, R Bacon |
Male Accessory Sex Organs | 1974 |
Extraction of the reduced nicotinamide adenine dinucleotide phosphate. Δ 4 -3-Ketosteroid-5α-oxidoreductase of rat prostate with digitonin and potassium chloride
RJ Moore, JD Wilson |
Biochemistry | 1974 |
In vitro effects of estrogens on rat prostatic 5α-reduction of testosterone
DK Lee, CE Bird, AF Clark |
Steroids | 1973 |
Temporal Aspects of Therapeutics
J Urquhart, FE Yates |
1973 | |
24. Tagung vom 13. bis 16. September 1972 in Hannover
HK Büscher, R Nagel |
1973 | |
Receptors for Reproductive Hormones
BW OMalley, AR Means |
1973 | |
HISTOLOGY OF THE PROSTATE IN ELDERLY MEN
TB Harbitz, OA Haugen |
Acta Pathologica Microbiologica Scandinavica Section A Pathology | 1972 |
The metabolism of testosterone and dihydrotestosterone in an androgen-dependent tumour. A possible correlation between dihydrotestosterone and tumour growth in vivo
N Bruchovsky |
Biochemical Journal | 1972 |
Androgen dynamics in vitro in the human prostate gland. Effect of oestradiol-17
EP Giorgi, JC Stewart, JK Grant, IM Shirley |
Biochemical Journal | 1972 |
Hormonal effects in vitro on prostatic ribonucleic acid polymerase
P Davies, AR Fahmy, CG Pierrepoint, K Griffiths |
Biochemical Journal | 1972 |
Androgen and estrogen uptake in the canine prostate and their excretion in prostatic fluid
MJ Varkarakis, RY Kirdani, GP Murphy, AA Sandberg |
Journal of Surgical Research | 1972 |
Quantification of free dihydrotestosterone in blood plasma and tissue
GC Haltmeyer, KB Eik-Nes |
Analytical Biochemistry | 1972 |
Receptors and binding of androgens in the prostate
A Aakvaag, KJ Tveter, O Unhjem, A Attramadal |
Journal of Steroid Biochemistry | 1972 |
Physicochemical properties of the 5α-dihydrotestosterone binding protein in human male serum
V Hansson, J Larsen, E Reusch |
Steroids | 1972 |
Plasma 5α-dihydrotestosterone (17β-hydroxy-5α-androstan-3-one) in adolescent males at different stages of sexual maturation
D Gupta, E McCafferty, K Rager |
Steroids | 1972 |
Recent Studies on the Mechanism of Action of Testosterone
D Deykin, C Balko, JD Wilson |
New England Journal of Medicine | 1972 |
Studies on the interaction between androgen and macromolecules in male accessory sex organs of rat and man
V Hansson, KJ Tveter, O Unhjem, O Djöseland |
Journal of Steroid Biochemistry | 1972 |
Urological Research
GP Murphy |
Urological Research | 1972 |
Pills for the Benign Prostate: Steroids and the Prostate
WB Peeling, K Griffiths |
Proceedings of the Royal Society of Medicine | 1972 |
In Vitro and in Vivo Studies on the Functional Significance of Androgen Receptors in Rat Prostate
P Rennie, N Bruchovsky |
The Journal of biological chemistry | 1972 |
Hormone metabolism and action: Testosterone and metabolites in prostate organ culture
P Robel, I Lasnitzki, EE Bauliec |
Biochimie | 1971 |
The effect of oestrogen on the prostatic metabolism of testosterone in tissue culture
M Groom, ME Harper, AR Fahmy, CG Pierrepoint, K Griffiths |
Biochemical Journal | 1971 |
A possible role of zinc in the metabolism of testosterone by the prostate gland
JK Grant, J Minguell, P Taylor, M Weiss |
Biochemical Journal | 1971 |
Proceedings of the 1970 Laurentian Hormone Conference
AR Midgley, GD Niswender, VL Gay, LE Reichert |
Proceedings of the 1970 Laurentian Hormone Conference | 1971 |
Haut als endokrines Erfolgsorgan Gestagene Geriatrische Endokrinologie des Mannes
J Kracht |
1971 | |
Partial Characterization of the Nuclear Reduced Nicotinamide Adenine Dinucleotide Phosphate: Δ4-3-Ketosteroid 5α-Oxidoreductase of Rat Prostate
DW Frederiksen, JD Wilson |
The Journal of biological chemistry | 1971 |
Dihydrotestosterone in prostatic hypertrophy I. The formation and content of dihydrotestosterone in the hypertrophic prostate of man
PK Siiteri, JD Wilson |
Journal of Clinical Investigation | 1970 |
Testosterone
DW Killinger |
Canadian Medical Association journal | 1970 |