Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Respiratory mechanics and dust exposure in byssinosis
A. Bouhuys, K. P. Van de Woestijne
A. Bouhuys, K. P. Van de Woestijne
Published January 1, 1970
Citation Information: J Clin Invest. 1970;49(1):106-118. https://doi.org/10.1172/JCI106209.
View: Text | PDF
Research Article Article has an altmetric score of 6

Respiratory mechanics and dust exposure in byssinosis

  • Text
  • PDF
Abstract

Acute exposures to hemp dust, in healthy subjects as well as hemp workers with byssinosis, resulted in two different responses. Men with symptoms (chest tightness, coughing, and wheezing) after exposure showed decreases of forced expiratory volumes (FEV1.0), flow rates on maximum expiratory flow-volume (MEFV) curves, and of vital capacity (VC), while airway conductance (Gaw: TGV ratio) did not decrease significantly (“flow rate response”). Men without symptoms after exposure showed no changes of VC, FEV1.0, and MEFV curves, but had a significantly decreased airway conductance (“conductance response”). The flow rate response is attributed to a pharmacological bronchoconstrictor effect of hemp dust on small airways, the conductance response to a mechanical or reflex effect of hemp dust on large airways. Both responses were abolished by a bronchodilator drug. The type of response reflects a difference between individuals and is not related to age, smoking habits, or prior exposure history. Men with normal control function data had either a flow rate or a conductance response. All men with abnormal control data had a flow rate response.

Authors

A. Bouhuys, K. P. Van de Woestijne

×

Total citations by year

Year: 2020 2015 2009 2006 2004 2003 2001 1989 1987 1986 1985 1984 1983 1982 1981 1979 1978 1977 1976 1975 1974 1973 1972 1971 1970 1960 Total
Citations: 1 1 1 2 1 1 1 1 1 2 3 4 1 1 2 4 1 3 8 4 6 9 2 3 2 1 66
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (66)

Title and authors Publication Year
Epidemiology of respiratory diseases and associated factors among female textile workers in Pakistan
M Khan, K Muhmood, S Noureen, HZ Mahmood, R Amir-ud-Din
International Journal of Occupational Safety and Ergonomics 2020
Triple therapy with salmeterol/fluticasone propionate 50/250 plus tiotropium bromide improve lung function versus individual treatments in moderate-to-severe Japanese COPD patients: a randomized controlled trial – Evaluation of Airway sGaw after treatment with tripLE
T Hayamizu, T Saito, A Takeda, K Hashimoto, A Kobayashi, G Hagan
International journal of chronic obstructive pulmonary disease 2015
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
A STUDY OF THE PREVALENCE OF RESPIRATORY MORBIDITY IN THE WORKERS OF TEXTILE INDUSTRY OF BARODA CITY
VM Shobha, PV Kotecha, GD Joshi
Medical Textiles and Biomaterials for Healthcare 2006
Medical Textiles and Biomaterials for Healthcare
VM Shobha, PV Kotecha, GD Joshi
Medical Textiles and Biomaterials for Healthcare 2006
Perioperative and Critical Care Medicine
A Gullo, G Berlot, U Lucangelo, T Pellis
2004
Comparison of FEV1and specific airway conductance in assessing airway response to occupational agents
A Larbanois, JP Delwiche, J Jamart, O Vandenplas
Allergy 2003
Radiologic Diagnosis of Chest Disease
M Sperber
2001
A study of the prevalence of ventilatory obstruction in textile workers exposed to cotton dust
SK Rastogi, BN Gupta, N Mathur, T Husain
Environmental Research 1989
Paradoxical response to nebulised salbutamol in wheezy infants, assessed by partial expiratory flow-volume curves
A Prendiville, S Green, M Silverman
Thorax 1987
Ventilatory impairment from pre-harvest retted flax
JP Jamison, JH Langlands, RC Lowry
British journal of industrial medicine 1986
Pulmonary Function in Normal Subjects and Patients with Sarcoidosis after Bronchoalveolar Lavage
DS Tilles, PD Goldenheim, LC Ginns, CA Hales
Chest 1986
Report of the Workshop on Environmentally Related Nononcogenic Lung Disease
JL Whittenberger
Environmental Research 1985
Ventilatory responses of normal subjects to flax dust inhalation: the protective effect of autoclaving the flax
JP Jamison, JH Langlands, CC Bodel
British journal of industrial medicine 1985
Estudio del efecto de la nifedipina sobre las vias aereas en pacientes afectos de broncopatia obstructiva cronica
JA Vilata, RL Llombart, JM Sesma, JM Gil, LI Perez, VL Merino
Archivos de Bronconeumología 1985
Application of a New Direct-Writing Recorder Device, the “Astograph,” to the Evaluation of Methacholine-Induced Bronchoconstriction in Asthmatic Children
M Mitsuhashi, K Tajima, K Tokuyama, A Morikawa, T Kuroume
Journal of Asthma 1984
Characterisation of textile dust extracts: II. Bronchoconstriction in man
JS Douglas, PG Duncan, E Zuskin
British journal of industrial medicine 1984
Cotton induced bronchoconstriction detected by a forced random noise oscillator
MJ Sepulveda, JL Hankinson, RM Castellan, JB Cocke
British journal of industrial medicine 1984
Clinical Tests of Respiratory Function
GJ Gibson
1984
Détection du bronchospasme lors du test de provocation
R Marcelle, J Juchmes, L Mottard, C Groetenbriel
Revue Française d'Allergologie et d'Immunologie Clinique 1983
Occupational asthma
D Sheppard
The Western journal of medicine 1982
WHAT INFECTIONS OCCUR IN PATIENTS WITH OCCUPATIONAL LUNG DISEASE?
J Balmes, MR Cullen, JB Gee
Clinics in Chest Medicine 1981
OCCUPATIONAL ASTHMA
IL Bernstein
Clinics in Chest Medicine 1981
Methods of study of airway smooth muscle and its physiology
HL Hahn, JA Nadel
Pharmacology & Therapeutics 1979
The Separation of Willebrand Factor from Factor VIII-Related Antigen
ES Barrow, HM Reisner, JB Graham
British Journal of Haematology 1979
The relative contributions of nature and nurture in chronic obstructive pulmonary disease
AS Buist
The Western journal of medicine 1979
Estudio comparativo del efecto broncodilatador del Sch-1000 y la isoprenalina en la broncopatia obstructiva cronica
RL Llombart, JM Sesma, VL Merino
Archivos de Bronconeumología 1979
Do present levels of air pollution outdoors affect respiratory health?
A Bouhuys, GJ Beck, JB Schoenberg
Nature 1978
Large airway constriction in allergic rhinitis
RD Fairshter, JT Chiu, AF Wilson, HS Novey
Journal of Allergy and Clinical Immunology 1977
Physiological patterns in early morning asthma
MR Hetzel, TJ Clark, K Houston
Thorax 1977
Time course of bronchoconstrictive response in asthmatic subjects to reduced temperature
JM Ramsey
Thorax 1977
Epidemiology of chronic lung disease in a cotton mill community
A Bouhuys, JB Schoenberg, GJ Beck, RS Schilling
Lung 1976
Cardiopulmonary effects of long-term bronchodilator administration
AF Wilson, HS Novey, P Cloninger, J Davis, D White
Journal of Allergy and Clinical Immunology 1976
Improvement of “irreversible” airway obstruction by thiazinamium (Multergan®)
A Bouhuys, J Ortega
Pneumonologie Pneumonology 1976
Effect of prostaglandin F2 alpha on lung mechanics in extrinsic asthma
KR Patel
Postgraduate medical journal 1976
Effects of an inhaled bronchodilator on gas distribution and over-all ventilatory efficiency in patients with chronic obstructive pulmonary disease
A Cutillo, R Perondi, M Turiel, S Monti
The American Journal of Medicine 1976
Pulmonary Function Testing in Asthmatic Children
JF Souhrada, JM Buckley
Pediatric Clinics of North America 1976
Pneumokoniosen
WT Ulmer, G Reichel, H Antweiler, H Bohlig, J Bruch, G Fruhmann, G Könn, WP Oellig, B Rasche, G Reichel, V Schejbal, W Stahlmann, WT Ulmer, W Walkenhorst, W Weller, G Worth
1976
Improvement of “irreversible” airway obstruction by thiazinamium (Multergan®)
A Bouhuys, J Ortega
Lung 1976
BRONCHOCONSTRICTION INDUCED BY REPEATED FORCED VITAL CAPACITY MANOEUVRES
AJ Roncoroni, E Goldman, RJ Puy, M Mancino
Allergy 1975
CHANGES IN PULMONARY FUNCTION IN WORKERS EXPOSED TO VINYL CHLORIDE AND POLYVINYL CHLORIDE
A Miller, AS Teirstein, M Chuang, IJ Selikoff, R Warshaw
Annals of the New York Academy of Sciences 1975
Screening tests for pulmonary function abnormality
A Miller
Environmental Health Perspectives 1975
Responses to Cotton Dust
JA Merchant, GM Halprin, AR Hudson, KH Kilburn, WN McKenzie, DJ Hurst, P Bermazohn
Archives of Environmental Health An International Journal 1975
The relationship of leucocyte adenyl cyclase activity and airways response to beta blockade and allergen challenge in extrinsic asthma
KR Patll, WC Lston, JW Kerr
Clinical & Experimental Allergy 1974
Inhalation challenge tests in asthma: an assessment of spirometry, maximum expiratory flow rates and plethysmography in measuring the responses
SP Haydu, DW Empey, DT Hughes
Clinical & Experimental Allergy 1974
EVALUATION BEFORE AND AFTER EXPOSURE?THE PATTERN OF PHYSIOLOGICAL RESPONSE TO COTTON DUST
JA Merchant, GM Halprin, AR Hudson, KH Kilburn, WM McKenzie, P Bermanzohn, DJ Hurst, JD Hamilton, VH Germino
Annals of the New York Academy of Sciences 1974
Bronchial component in chronic obstructive lung disease
SM Ayres, SJ Griesbach, F Reimold, RG Evans
The American Journal of Medicine 1974
Response of the lung to inhaled antigens
DP Schlueter
The American Journal of Medicine 1974
Detection of Airway Obstruction in Exercise-Induced Asthma
JM Buckley, JF Souhrada, MT Kopetzky
Chest 1974
Factors Determining the Shape of Maximum Expiratory Flow-Volume Curves in Childhood Asthma
LI Landau, DJ Hill, PD Phelan
Australian and New Zealand Journal of Medicine 1973
Pharmacological prevention of acute ventilatory capacity reduction in flax dust exposure
F Valić, E Zuskin
British journal of industrial medicine 1973
A PHYSIOLOGICAL STUDY OF BYSSINOSIS IN COLONIAL AMERICA*
A Bouhuys, CA Mitchell, RS Schilling, E Zuskin
Transactions of the New York Academy of Sciences 1973
Effect of acute exposure to CO2 on lung mechanics in normal man
JR Rodarte, RE Hyatt
Respiration Physiology 1973
Occupational Health Practice
ML Thomson
Occupational Health Practice 1973
Asthma without Wheezing
RS Farr, MT Kopetzky, SL Spector, DS Hurewitz
Chest 1973
Early Detection of Obstructive Lung Disease by Analysis of Maximal Expiratory Flow-Volume Curves
AF Gelb, BJ MacAnally
Chest 1973
Pulmonary resistance and maximal expiratory flow-rates following isoprenaline in patients with chronic obstructive lung disease
DC Stanescu, J Clement, KP Woestijne
Thorax 1973
The Genetics of Hereditary Disorders of Blood Coagulation: Functional and immunological studies provide evidence for the heterogeneity of many familial clotting disorders
OD Ratnoff, B Bennett
Science 1973
Byssinosis
HE Ayer, KH Kilburn
C R C Critical Reviews in Environmental Control 1972
The Use of Expiratory Forced Flows for Determining Response to Bronchodilator Therapy
SF Boushy
Chest 1972
Clinical Experience with a New Test of Pulmonary Function
BJ Sobol
Chest 1971
Factor VIII Detection by Hemagglutination Inhibition: Hemophilia A and von Willebrand's Disease
DP Stites, EJ Hershgold, JD Perlman, HH Fudenberg
Science 1971
New Tests of Airway Obstruction and Their Clinical Applications: Assessment of Airway Obstruction: Which Test is Best?
BJ Sobol
Proceedings of the Royal Society of Medicine 1971
Purification of human antihemophilic factor (factor VIII) by gel chromatography
JA Mourik, IA Mochtar
Biochimica et Biophysica Acta (BBA) - Protein Structure 1970
Control of Environmental Lung Disease
A Bouhuys, JM Peters
New England Journal of Medicine 1970
The Plasma Proteins
ML Petermann
The Plasma Proteins 1960

← Previous 1 2 3 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 1 policy sources
Referenced in 1 clinical guideline sources
5 readers on Mendeley
See more details