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Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of β2-microglobulin, albumin, and total protein
Per A. Peterson, … , Per-Eric Evrin, Ingemar Berggård
Per A. Peterson, … , Per-Eric Evrin, Ingemar Berggård
Published July 1, 1969
Citation Information: J Clin Invest. 1969;48(7):1189-1198. https://doi.org/10.1172/JCI106083.
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Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of β2-microglobulin, albumin, and total protein

Abstract

A low molecular weight β2-globulin (β2-microglobulin), albumin, and total protein were measured in concentrated 24-hr urine specimens from 20 healthy subjects and 30 patients with clinical proteinuria of glomerular or tubular type. Classification of proteinuria was made on the basis of clinical diagnosis and size distribution of urinary proteins after gel chromatography. The molecular radii (Stokes' radii) of β2-microglobulin and albumin, estimated by gel chromatography, were 15 A and 35 A.

Authors

Per A. Peterson, Per-Eric Evrin, Ingemar Berggård

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MD Donaldson, RE Chambers, MW Woolridge, JT Whicher 		Pediatric Nephrology 1990
Assessment of tubular function in neonates using urinary ?2-microglobulin
H Tsukahara, M Yoshimoto, M Saito, T Sakaguchi, I Mitsuyoshi, S Hayashi, K Nakamura, K Kikuchi, M Sudo 		Pediatric Nephrology 1990
Early Phase Drug Evaluation in Man
J OGrady, OI Linet 		1990
Reversible low-molecular-weight proteinuria in patients with distal renal tubular acidosis.
Igarashi T, Kawato H, Kamoshita S 		Pediatric nephrology (Berlin, Germany) 1990
Cisplatin nephrotoxicity
G Daugaard, U Abildgaard 		Cancer Chemotherapy and Pharmacology 1989
Markers of tubular dysfunction
M Piscator 		Toxicology Letters 1989
Intrathecal synthesis of beta-2-microglobulin in multiple sclerosis and aseptic meningo-encephalitis
Ö Us, F Lolli, S Baig, H Link 		Acta Neurologica Scandinavica 1989
Beta-2-microglobulin in the cerebrospinal fluid of patients with infections of the central nervous system
NA Peterslund, FT Black, JP Geil, CE Mogensen 		Acta Neurologica Scandinavica 1989
Importance of Residual Renal Function in End-Stage Renal Disease
RI Lynn, DA Feinfeld 		Seminars in Dialysis 1989
Impaired renal tubular function in chronic alcoholics
M Labib, M Abdel-Kader, L Ranganath, S Martin, V Marks 		Journal of the Royal Society of Medicine 1989
Kidney function in newly diagnosed Type 2 (non-insulin-dependent) diabetic patients, before and during treatment
A Schmitz, HH Hansen, T Christensen 		Diabetologia 1989
Cisplatin nephrotoxicity: A review
G Daugaard, U Abildgaard 		Cancer Chemotherapy and Pharmacology 1989
Diagnostic significance of salivary levels ofβ2-microglobulin in Sjögren's syndrome
AJ Swaak, LL Visch, A Zonneveld 		Clinical Rheumatology 1988
Prednisolone can increase glomerular permeability to proteins in nephrotic syndrome
JF Wetzels, HE Sluiter, AJ Hoitsma, PJ van Munster, RA Koene 		Kidney International 1988
The renal uptake of proteins: A nonselective process in conscious rats
A Bernard, AO Amor, C Viau, R Lauwerys 		Kidney International 1988
Plasma levels of 7B2 (a novel pituitary polypeptide) and its molecular forms in plasma and urine in patients with chronic renal failure: possible degradation by the kidney
H Iguchi, S Natori, Y Ou, H Nawata, K Kato, H Ibayashi, SR Bloom 		Regulatory Peptides 1988
The classification and definition of the hypertensive disorders of pregnancy
DA Davey, I MacGillivray 		American Journal of Obstetrics and Gynecology 1988
Urinary Doubly Refractile Lipid Bodies in Nonglomerular Renal Diseases
GL Braden, PG Sanchez, JP Fitzgibbons, WJ Stupak, MJ Germain 		American Journal of Kidney Diseases 1988
Asymptomatic proteinuria: Benign disorder or harbinger of disease?
J Striegel, AF Michael, BM Chavers 		Postgraduate Medicine 1988
Urinary protein excretion patterns in reactive (secondary) systemic amyloidosis
, CP Maury 		Rheumatology International 1988
An Immunoturbidimetric Method for the Measurement of Beta-2 Microglobulin in Serum and Plasma on a Centrifugal Analyser
CR Tillyer, Y Rawal 		Annals of Clinical Biochemistry 1988
Effects of cisplatin on different measures of glomerular function in the human kidney with special emphasis on high-dose
G Daugaard, N Rossing, M Rrth 		Cancer Chemotherapy and Pharmacology 1988
Changes in renal function in response to protein restricted diet in Type 1 (insulin-dependent) diabetic patients
MJ Wiseman, E Bognetti, R Dodds, H Keen, GC Viberti 		Diabetologia 1987
Renal excretion and cyst accumulation of β2microglobulin in polycystic kidney disease
N Birenboim, VS Donoso, RA Huseman, JJ Grantham 		Kidney International 1987
Effect of protein restriction in insulin dependent diabetics at risk of nephropathy
D Cohen, R Dodds, G Viberti 		British medical journal (Clinical research ed.) 1987
Serial measurements of beta-2-microglobulin in plasma correlates with white blood cell counts and haptocorrin in chronic myeloid leukemia
OW Bjerrum, P Gimsing 		Leukemia Research 1987
Retinol-binding protein, albumin and total protein excretion patterns during normal pregnancy
G Gerö, F Anthony, M Davis, MC Richardson, KJ Dennis, DJ Rowe 		Journal of Obstetrics & Gynaecology 1987
A simplified enzyme-linked immunosorbent assay for urinary albumin
O Torffvit, JÖ Wieslander 		Scandinavian Journal of Clinical & Laboratory Investigation 1986
Use of β2 microglobulin to diagnose tubulo-interstitial renal lesions in children
RJ Portman, JM Kissane, AM Robson, LJ Peterson, A Richardson 		Kidney International 1986
Measurement of beta-2-microglobulin in human cerebrospinal fluid by ELISA technique
OW Bjerrum, S Lage, OE Hansen 		Acta Neurologica Scandinavica 1986
Microalbuminuria in Elderly Hyperglycaemic Patients and Controls
EM Damsgaard, CE Mogensen 		Diabetic Medicine 1986
The cellular basis of renal injury by radiation
MV Williams 		The British journal of cancer. Supplement 1986
A competitive enzyme immunoassay of human β2-microglobulin based on separation by filtration
R Brandt, E Hedlöf, S Åsberg, JG Gustavsson, J Carlsson 		Journal of Immunological Methods 1986
The kidney in diabetes: Significance of the early abnormalities
GC Viberti, MJ Wiseman 		Clinics in Endocrinology and Metabolism 1986
Specific Binding Sites for Monomeric and Aggregated β 2 -Microglobulin on Surface of Groups A, B, C, and G Streptococci
GS Chhatwal, IS Dutra, H Blobel 		Microbiology and Immunology 1986
Measurement of beta-2-microglobulin in serum and plasma by an enzyme-linked immunosorbent assay (ELISA)
OW Bjerrum, HS Birgens 		Clinica Chimica Acta 1986
The effects of arginine, dextran and Haemaccel infusions on urinary albumin, β2-microglobulin and
DS O'Reilly, ES Parry, JT Whicher 		Clinica Chimica Acta 1986
Early Biological Indicators of S-(1,2-Dichlorovinyl)-L-Cysteine Nephrotoxicity in the Rabbit
PM Silber, AJ Gandolfi, K Brendel 		Drug and Chemical Toxicology 1986
The Classification and Definition of the Hypertensive Disorders of Pregnancy: Proposals Submitted to the International Society for the Study of Hypertension in Pregnancy
DA Davey, I Macgillivray 		Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy 1986
N-Acetyl-β-D-Glucosaminidase Enzymuria in Leukaemia and Myelomatosis: Effect of Treatment in Acute Myeloblastic Leukaemia and Myelomatosis in Adults
PH Whiting, DJ King, A Ireland, MA Ratcliffe, AA Dawson 		Annals of Clinical Biochemistry 1986
Cadmium
EC Foulkes 		1986
Investigating renal function during lithium treatment
DG Waller, JG Edwards 		Psychological Medicine 1985
Immunological Studies in a Patient with the Glucagonoma Syndrome
M Dohlsten, T Hallberg 		Acta Medica Scandinavica 1985
Tubular dysfunction in the deeply jaundiced patient with hepatorenal syndrome
WG Rector, GC Kanel, J Rakela, TB Reynolds 		Hepatology 1985
Beta 2-microglobulin clearance in neonates: Index of tubular maturation
FK Assadi, EG John, P Justice, L Fornell 		Kidney International 1985
Electrical charge of serum and urinary albumin in normal and diabetic humans
GM Ghiggeri, G Candiano, G Delfino, C Queirolo 		Kidney International 1985
Beta 2 microglobulins: A brief comparative review
GW Warr 		Developmental & Comparative Immunology 1985
Serum Concentration of Cystatin C, Factor D and β2-Microglobulin as a Measure of Glomerular Filtration Rate
A Grubb, O Simonsen, G Sturfelt, L Truedsson, H Thysell 		Acta Medica Scandinavica 1985
Renal Effects of Chronic Exposure to Organic Solvents
L Krusell, HK Nielsen, J Baelum, G Lundqvist, Ø Omland, M Vaeth, SE Husted, CE Mogensen, E Geday 		Acta Medica Scandinavica 1985
The blood serum concentration of cystatin C (γ-trace) as a measure of the glomerular filtration rate
O Simonsen, A Grubb, H Thysell 		Scandinavian Journal of Clinical & Laboratory Investigation 1985
Beta-2-microglobulin: A valuable parameter of stage, prognosis and response to treatment in myelomatosis
OW Bjerrum, T Plesner 		Scandinavian Journal of Haematology 1985
Renal Effects of Acute Exposure to Toluene
HK Nielsen, L Krusell, J Baelum, G Lundqvist, Ø Omland, M Vaeth, SE Husted, CE Mogensen, E Geday 		Acta Medica Scandinavica 1985
Aspects on Tubular Proteinuria
L Wibell 		Upsala Journal of Medical Sciences 1985
Monitoring Progression of Diabetic Nephropathy
HH Parving, AR Andersen, UM Smidt 		Upsala Journal of Medical Sciences 1985
Tubular Proteinuria in Renal Calcium Stone Formers
B Wikström, U Backman, BG Danielson, B Fellström, G Johansson, S Ljunghall 		Upsala Journal of Medical Sciences 1985
Proteinuria and Renal Function in Kidney Transplant Donors 10–18 Years after Donor Uninephrectomy
Ö Mathillas, PO Attman, M Aurell, I Blohmé, H Brynger, G Granérus, G Westberg 		Upsala Journal of Medical Sciences 1985
Fluorimetric enzyme immunoassay for serum β2-microglobulin based on the horseradish peroxidase-labeled Fab′ fragment of immunoglobulin
K Sugimoto, K Zaitsu, Y Ohkura 		Analytica Chimica Acta 1985
Nephrologie — Urologie
J Brodehl 		1985
Effects on renal tubular protein reabsorption of the infusion of free haemoglobin
JT Whicher, ES Parry 		European Journal of Clinical Investigation 1984
Glycosyl albumin and diabetic microalbuminuria: Demonstration of an altered renal handling
GM Ghiggeri, G Candiano, G Delfino, F Bianchini, C Queirolo 		Kidney International 1984
A solid phase fluorescent immunoassay for the measurement of human urinary albumin
BM Chavers, J Simonson, AF Michael 		Kidney International 1984
Copper and zinc levels in serum and urine of cadmium-exposed people with special reference to renal tubular damage
K Nogawa, Y Yamada, R Honda, I Tsuritani, E Kobayashi, M Ishizaki 		Environmental Research 1984
Renal impairment after high doses of dicloxacillin-prophylaxis in joint replacement surgery
J Isacson, S Collert 		Acta Orthopaedica 1984
Glomerular function and hyperuricaemia in sickle cell disease
AG Morgan, KD Ceulaer, GR Serjeant 		Journal of clinical pathology 1984
Urinary albumin excretion in school children
AG Davies, RJ Postlethwaite, DA Price, JL Burn, CA Houlton, BA Fielding 		Archives of disease in childhood 1984
A two-site sandwich radioimmunoassay of β2-microglobulin with monoclonal antibodies
K Tachibana, E Tanaka, S Usuda, H Okamoto, M Imai, T Nakamura, Y Miyakawa, M Mayumi 		Journal of Immunological Methods 1984
Unilateral radiation nephropathy—the long-term significance
TH Kim, PJ Somerville, CR Freeman 		International journal of radiation oncology, biology, physics 1984
The Retinoids
BA Underwood 		The Retinoids 1984
Isolation and purification of human serum β2-microglobulin from the hemodialysis ultrafiltrate of patients with chronic renal failure
TG Chung, S Akira, O Hiroshi, M Akihiko, O Iwao, S Makoto 		Clinica Chimica Acta 1984
Clinical Biochemistry
E Cooper, M Bowen 		Clinical Biochemistry 1984
Examination of Kidney Function
O Schück 		1984
The natural history of diabetic nephropathy in type I diabetes and the role of metabolic control in its prevention, reversibility and clinical course
BL Wajchenberg, E Sabbaga, JA Fonseca 		Acta Diabetologica Latina 1984
The natural history of diabetic nephropathy in type I diabetes and the role of metabolic control in its prevention, reversibility and clinical course
BL Wajchenberg, E Sabbaga, JA Fonseca 		Acta Diabetologica Latina 1984
Failure of sodium aurothiomalate and triethyl phosphine gold to cause renal tubular injury in rheumatoid arthritis: implications for the aetiology of gold-related nephropathy
AJ Crisp, RJ Coughlan, B Clark, D Mackintosh, GS Panayi, P Sweny, J Hopper, Z Varghese 		Clinical Rheumatology 1983
GLOMERULAR TUBULAR BALANCE IN PRETERM AND FULLTERM INFANTS
A Aperia, O Broberger, U Broberger, P Herin, R Zetterström 		Acta Paediatrica 1983
Renal handling of beta-2-microglobulin in the human neonate
WD Engle, BS Arant 		Kidney International 1983
Elevation of urinary trehalase in mercuric chloride-induced nephrotoxic rabbits: Urinary trehalase as a specific indicator of renal brush border damage
M Nakano, G Itoh 		Chemico-Biological Interactions 1983
Proteinuria
M Barratt 		British medical journal (Clinical research ed.) 1983
Disposition of human fibrinopeptide A in normal and nephrectomized rabbits
J Harenberg, G Stehle, S Waibel, HJ Hermann, M Eisenhut, R Zimmermann 		Thrombosis Research 1983
A simple, precise and sensitive nephelometric assay for β2-Microglobulin in body fluids
D O'Reilly, J Whicher, AR Sanderson 		Journal of Immunological Methods 1983
Proteinuria in children with insulin-dependent diabetes: Relationship to duration of disease, metabolic control, and retinal changes
D Ellis, DJ Becker, D Daneman, L Lobes, AL Drash 		The Journal of Pediatrics 1983
Monitoring glomerular function in diabetic nephropathy
GC Viberti, RW Bilous, D Mackintosh, H Keen 		The American Journal of Medicine 1983
Specificity of Renal Tubular Damage Criteria for Aminoglycoside Nephrotoxicity in Critically III Patients
JJ Schentag 		The Journal of Clinical Pharmacology 1983
Luminescence catalyst immunoassay of β2-microglobulin with haemin as a chemically amplifiable label
Y Ikariyama, S Suzuki, M Aizawa 		Enzyme and microbial technology 1983
Nephronophthisis With Massive Proteinuria
AR Eiser, E Grishman, MS Neff, J Allerhand, RF Slifkin 		American Journal of Kidney Diseases 1983
Nephrology Forum
JJ Cohen, JT Harrington, JP Kassirer 		1983
Quantitative determination of urinary protein components of children with postural proteinuria
Y Suzuki, S Shimao, T Okada, F Ishimoto, N Akiba 		European Journal of Pediatrics 1983
An evaluation of renal function in workers occupationally exposed to mercury vapour
MD Stonard, BV Chater, DP Duffield, AL Nevitt, JJ O'Sullivan, GT Steel 		International Archives of Occupational and Environmental Health 1983
Dose-effect relationship between cadmium and? 2-microglobulin in the urine of inhabitants of cadmium-polluted areas (Japan)
K Nomiyama, M Yotoriyama, H Nomiyama 		Archives of Environmental Contamination and Toxicology 1983
Urinary protein excretion in interstitial and tubular kidney disease as characterized by gradient electrophoresis
JM Alt, M Hacke, D Heyde, H Jnig, , C Olbricht, , H Stolte 		Klinische Wochenschrift 1983
Proteinuria in diabetes
D Mackintosh, GC Viberti, H Keen 		Diabetologia 1983
Partial Amino-Acid Sequence of the Epidermal Growth-Factor-Binding Protein
H ANUNDI, H RONNE, PA PETERSON, L RASK 		European Journal of Biochemistry 1982
Recurrent focal sclerosis after renal transplantation
EJ Lewis 		Kidney International 1982
Proteinuria in diabetes mellitus: Role of spontaneous and experimental variation of glycemia
GC Viberti, D Mackintosh, RW Bilous, JC Pickup, H Keen 		Kidney International 1982
Elimination of Low Molecular Weight Proteins During Hemofiltration
A Röckel, U Gilge, A Liewald, A Heidland 		Artificial Organs 1982
URINARY EXCRETION OF ALBUMIN AND BETA-2-MICROGLOBULIN, GLOMERULAR FILTRATION RATE AND IMMUNE COMPLEXES IN SERUM DURING INFECTIOUS MONONUCLEOSIS
EB Pedersen, J SØLling, CE Mogensen, KD Christensen 		Acta Pathologica Microbiologica Scandinavica Series C: Immunology 1982
Assessment of nephrotoxicity
LF Prescott 		British Journal of Clinical Pharmacology 1982
Neonatal hyperbilirubinemia and renal function
WD Engle, BS Arant 		The Journal of Pediatrics 1982
Disorders of Mineral Metabolism
RK Rude, FR Singer 		Disorders of Mineral Metabolism 1982
The Amylase to Creatinine Clearance Ratio: Is It a Suitable Test for the Diagnosis of Acute Pancreatitis?
G Jacobson 		Scandinavian Journal of Gastroenterology 1982
Gentamicin and sisomicin ? Induced renal tubular damage
G Nicot, L Merle, , , G Lachtre 		European Journal of Clinical Pharmacology 1982
Assessment of Renal Tubular Function and Damage and Their Clinical Significance
DB Morgan 		Annals of Clinical Biochemistry 1982
Serumβ 2-microglobulin and other “tumor associated” antigens in patients with bronchogenic carcinoma
C Mordasini, W Riesen, A Morell 		Lung 1982
Exercise-induced proteinuria in children and adolescents
NP Huttunen, ML Käär, M Pietiläinen, P Vierikko, M Reinilä 		Scandinavian Journal of Clinical & Laboratory Investigation 1981
Urinary β2 microglobulin in the newborn
KP Dawson, D Yeoman 		Journal of Paediatrics and Child Health 1981
Evaluation of renal tubular damage in liver cirrhosis by urinary enzymes and beta-2-microglobulin excretions
A Gatta, P Amodio, A Frigo, C Merkel, L Milani, R Zuin, A Ruol 		European Journal of Clinical Investigation 1981
β2-Microglobulin Levels in Serum and Urine of Cadmium Exposed Rabbits
M Piscator, L Björck, M Nordberg 		Acta Pharmacologica et Toxicologica 1981
Cytological shift in lymphocytes induced by cadmium in mice and rats
M Ohsawa, K Kawai 		Environmental Research 1981
Studies on β2-microglobulin in the rabbit
L Björck, I Berggård 		Molecular Immunology 1981
Urinary excretion of albumin, beta-2-microglobulin and light chains in pre-eclampsia, essential hypertension in pregnancy and normotensive pregnant and non-pregnant control subjects
EB Pedersen, AB Rasmussen, P Johannesen, S Kristensen, JG Lauritsen, CE Mogensen, K Sølling, M Wohlert 		Scandinavian Journal of Clinical & Laboratory Investigation 1981
Diagnostic value of a test-strip in detecting increased urinary excretion of albumin, IgG and β2-microglobulin in patients with suspected proteinuria
L Hemmingsen, P Skaarup 		Scandinavian Journal of Clinical & Laboratory Investigation 1981
Glomerular epithelial cell changes in early postischemic acute renal failure in rabbits and man
K Solez, LC Racusen, A Whelton 		The American Journal of Pathology 1981
Urinary beta 2 microglobulin in the biological monitoring of cadmium workers
M Stewart, EG Hughes 		British journal of industrial medicine 1981
beta 2-Microglobulin levels in serum and urine of rheumatoid arthritis patients on gold therapy
D Latt, JB Weiss, MI Jayson 		Annals of the rheumatic diseases 1981
Beta 2-microglobulinaemia: a sensitive index of diminishing renal function in diabetics
GC Viberti, H Keen, D Mackintosh 		British medical journal (Clinical research ed.) 1981
Exposure and health effects of cadmium part 2. Toxic effects of cadmium to animals and man
J. W. Copius Peereboom, Jenny H. J. Copius, Peereboom‐Stegeman 		Toxicological and Environmental Chemistry 1981
Quantification of β2-microglobulin by inhibition enzyme immunoassay
Y Carlier, A Colle, P Tachon, D Bout, A Capron 		Journal of Immunological Methods 1981
Reversible hyperinsulinuria in diabetic ketoacidosis in man
H Sacks, R Rabkin, AE Kitabchi 		American journal of physiology. Endocrinology and metabolism 1981
Genesis and evolution of diabetic nephropathy
H Keen, GC Viberti 		Journal of clinical pathology 1981
Isolated proteinuria in asymptomatic patients
RR Robinson 		Kidney International 1980
Turnover in humans of β2-microglobulin: the constant chain of HLA-antigens
FA Karlsson, T Groth, K Sege, L Wibell, PA Peterson 		European Journal of Clinical Investigation 1980
Feto-specific proteins in prenatal diagnosis
DJ Brock 		Molecular Aspects of Medicine 1980
Immunochemical Studies of Human ?2-Microglobulin
T Plesner 		Allergy 1980
Patterns of urinary β2-microglobulin excretion by patients treated with aminoglycosides
JJ Schentag, ME Plaut 		Kidney International 1980
The effect of low molecular weight protein loads on renal tubular function
JT Whicher, ES Parry 		La Ricerca in Clinica e in Laboratorio 1980
Transcapillary protein escape in arterial hypertension
G Bianchi, D Cusi, C Barlassina, L Duzzi, AM Caravaggi, G Lupi, M Gatti, O Velis, G Como, G Salvioli 		La Ricerca in Clinica e in Laboratorio 1980
β2-Microglobulin: Structure, Function and Significance
GM Bernier 		Vox Sanguinis 1980
Serum and Urinary Myoglobin in Alcoholics
R Hällgren, L Lundin, LE Roxin, P Venge 		Acta Medica Scandinavica 1980
Urinary excretion of β2-microglobulin in myeloma patients
W Engström, L Hyldahl, P Wahrgren 		Clinica Chimica Acta 1980
Urine B2-microglobulin in patients with macroglobulinemia Waldenström
W Engström, P Wahrgren 		Clinica Chimica Acta 1980
A comparative study of serum α1-microglobulin and β2-microglobulin levels in cancerous and other diseases
T Kimiteru, I Yoshihisa, E Hiromitsu, K Yoshihiro, M Kanzo, K Tadashi 		Clinica Chimica Acta 1980
Quantitative Studies on Antibiotic Nephrotoxicity
B Trollfors 		Scandinavian Journal of Infectious Diseases 1980
Light chain polymerism in normal individuals, in patients with severe proteinuria and in normals with inhibited tubular protein reabsorption by lysine
K SøLling 		Scandinavian Journal of Clinical & Laboratory Investigation 1980
Urinary Albumin and β 2 -Microglobulin Excretion Rates in Patients with Systemic Lupus Erythematosus
HH Parving, SF Sørensen, CE Mogensen, P Helin 		Scandinavian Journal of Rheumatology 1980
Malumfashi Endemic Diseases Research Project, XV: The potential medical importance of bilharzia in northern Nigeria: a suggested rapid, cheap and effective solution for control of Schistosoma haematobium infectino
RN Pugh, DR Bell, HM Gilles 		Annals of Tropical Medicine and Parasitology 1980
Verhandlungen der Deutschen Gesellschaft für innere Medizin
B Schlegel 		1980
Human alpha 1-microglobulin levels in various body fluids
K Takagi, K Kin, Y Itoh, H Enomoto, T Kawai 		Journal of clinical pathology 1980
Protein filtration and secretion at human body fluid barriers
K Felgenhauer 		Pflügers Archiv - European Journal of Physiology 1980
Urinary protein excretion in workers exposed to low doses of cadmium
SH Sandifer, RT Wilkins, NH Whitlock, G Virella, CB Loadholt, TC Leitner 		Bulletin of Environmental Contamination and Toxicology 1979
Hyperparathyroidism Associated with Distal Tubular Dysfunction but Intact Reabsorption of Protein in the Proximal Tubules
L Wibell, PA Dahlberg, A Karlsson 		Acta Medica Scandinavica 1979
Determination of carbonic anhydrase C and β2-microglobulin by radioimmunoassay in urine of heavy-metal-exposed subjects and patients with renal tubular acidosis
N Taniguchi, M Tanaka, C Kishihara, H Ohno, T Kondo, I Matsuda, T Fujino, M Harada 		Environmental Research 1979
Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review
T Maack, V Johnson, ST Kau, J Figueiredo, D Sigulem 		Kidney International 1979
Renal excretion of proteins and enzymes in workers exposed to cadmium
A Bernard, JP Buchet, H Roels, P Masson, R Lauwerys 		European Journal of Clinical Investigation 1979
Micro vascular permeability to albumin and glomerular filtration rate in diabetic and normal children
J Br�chner-Mortensen, J Ditzel, CE Mogensen, P R�dbro 		Diabetologia 1979
Demonstration of a murine cell surface component with affinity for exogenous β2-microglobulin
K Sege, L Östberg, PA Peterson 		European Journal of Immunology 1979
Abnormal albumin excretion after two provocative renal tests in diabetes: Physical exercise and lysine injection
CE Mogensen, E Vittinghus, K Sølling 		Kidney International 1979
Rat β2-microglobulin isolation, properties and relation to β2-microglobulins from other species
L Lögdberg, PO Östergren, I Berggård 		Molecular Immunology 1979
Serum β2- microglobulin in liver disease
R Hällgren 		Scandinavian Journal of Clinical & Laboratory Investigation 1979
The Effect of Cimetidine, a New Histamine H2-Receptor Antagonist, on Renal Function
R Larsson, G Bodemar, B Kågedal 		Acta Medica Scandinavica 1979
EVIDENCE OF CADMIUM TOXICITY IN A POPULATION LIVING IN A ZINC-MINING AREA
M Carruthers, B Smith 		The Lancet 1979
URINARY β2-MICROGLOBULIN IN UPPER AND LOWER URINARY-TRACT INFECTIONS
G Schardijn, LW van Eps, AJ Swaak, JC Kager, JP Persijn 		The Lancet 1979
Amniotic Fluid β2Microglobulin: Correlation with L/S Ratios and Creatinine Levels
MN Cauchi, D Goriup, I Horacek 		The Australian and New Zealand Journal of Obstetrics and Gynaecology 1979
Urinary casts as an indicator of renal tubular damage in patients receiving aminoglycosides
JJ Schentag, FM Gengo, ME Plaut, D Danner, A Mangione, WJ Jusko 		Antimicrobial agents and chemotherapy 1979
Aminoglycoside nephrotoxicity in critically iii surgical patients
JJ Schentag, ME Plaut, FB Cerra, PB Wels, P Walczak, RJ Buckley 		Journal of Surgical Research 1979
Nerve growth factor binds to serum alpha-2-macroglobulin
H Ronne, H Anundi, L Rask, PA Peterson 		Biochemical and Biophysical Research Communications 1979
Effect of Control of Blood Glucose on Urinary Excretion of Albumin and β 2 Microglobulin in Insulin-Dependent Diabetes
GC Viberti, JC Pickup, RJ Jarrett, H Keen 		New England Journal of Medicine 1979
BETA-2-MICROGLOBULIN, AN INDICATOR OF RENAL TUBULAR MATURATION AND DYSFUNCTION IN THE NEWBORN
A APERIA, U BROBERGER 		Acta Pdiatrica 1979
A PROSPECTIVE STUDY OF URINARY PROTEINS IN EARLY INFANCY
FA Karlsson, LI Hardell, K Hellsing 		Acta Pdiatrica 1979
β 2 -Microglobulin: Methods and Clinical Applications
MD Poulik, P Gold, J Shuster, GM Bernier 		Critical Reviews in Clinical Laboratory Sciences 1979
Fragmentation of the human transplantation antigen heavy chain by limited proteolysis, acid cleavage, and cyanogen bromide treatment
L Tragardh, K Wiman, L Rask, PA Peterson 		Biochemistry 1979
Serum Beta-2-Microglobulin Levels in Urological Cancer
RA Bunning, SL Haworth, EH Cooper 		The Journal of Urology 1979
Replacement of Renal Function by Dialysis
W Drukker, FM Parsons, JF Maher 		1979
Experimentelle und klinische Untersuchungen zur Differentialdiagnostik der Proteinurie
H Stolte, J Alt, 		Klinische Wochenschrift 1979
Renal Function in Patients on Lithium Treatment
R Hällgren, PO Alm, K Hellsing 		The British Journal of Psychiatry 1979
Micro vascular permeability to albumin and glomerular filtration rate in diabetic and normal children
J Brchner-Mortensen, J Ditzel, CE Mogensen, P Rdbro 		Diabetologia 1979
Abnormal amino acid and protein metabolism in uremia
JD Kopple 		Kidney International 1978
Renal glomerular and tubular impairment during strenuous exercise in young women
JR Poortmans, B Vancalck 		European Journal of Clinical Investigation 1978
RENAL TUBULAR FUNCTION IN NORMAL PREGNANCY
AM Kelly, MB McNay, HP McEwan 		BJOG: An International Journal of Obstetrics and Gynaecology 1978
Reactivity of a Rabbit Antiserum against Highly Purified HLA-DR Antigens
L Klareskog, L Tragardh, JB Lindblom, PA Peterson 		Scandinavian Journal of Immunology 1978
Cerebrospinal fluid β2-microglobulin in neurological disorders
R Tenhunen, M Iivanainen, J Kovanen 		Acta Neurologica Scandinavica 1978
The Diagnostic Value of Protein Clearances in Rejection of Human Renal Allografts
L Hemmingsen, H Jensen, P Jest, DP Skaarup 		Acta Medica Scandinavica 1978
Use of anti-idiotypic antibodies as cell-surface receptor probes
K Sege, PA Peterson 		Proceedings of the National Academy of Sciences 1978
Case 28-1978: The Nephrotic Syndrome and Renal Failure in a 70-Year-Old Man
RC Cabot, RE Scully, JJ Galdabini, BU McNeely, BD Rose, RB Colvin 		New England Journal of Medicine 1978
New Aspects of Cephalosporins: A Symposium of Glaxo, Sweden: Skövde, October 28–29 1977
R Norrby 		Scandinavian Journal of Infectious Diseases 1978
Evaluation of urinary myoglobin assay test for myocardial infarction
FA Karlsson, LE Roxin, P Venge, L Wibell 		Scandinavian Journal of Clinical & Laboratory Investigation 1978
The Value of the Amylase/Creatinine Clearance Ratio in the Diagnosis of Acute Pancreatitis
AR Solomon 		Critical Reviews in Clinical Laboratory Sciences 1978
Unique human glycoprotein, 7alpha;1-microglycoprotein: isolation from the urine of a cancer patient and its characterization
BK Seon, D Pressman 		Biochemistry 1978
Increased glomerular permeability to albumin induced by exercise in diabetic subjects
GC Viberti, RJ Jarrett, M McCartney, H Keen 		Diabetologia 1978
?2-microglobulin and other proteins in serum and urine during preeclampsia
M Weise, D Prfer, D Neubser 		Klinische Wochenschrift 1978
A comparison between fecal cadmium and urinary β2-microglobulin, total protein, and cadmium among Japanese farmers
S Kojima, Y Haga, T Kurihara, T Yamawaki, T Kjellström 		Environmental Research 1977
Urine analysis for detection of cadmium-induced renal changes, with special reference to β2-microglobulin
K Shiroishi, T Kjellström, K Kubota, PE Evrin, M Anayama, O Vesterberg, T Shimada, M Piscator, T Iwata, H Nishino 		Environmental Research 1977
Dose-response analysis of cadmium-induced tubular proteinuria
T Kjellström, PE Evrin, B Rahnster 		Environmental Research 1977
Urinary β2-microglobulin excretion among people exposed to cadmium in the general environment
T Kjellström, K Shiroishi, PE Evrin 		Environmental Research 1977
Studies on renal tubular protein reabsorption: Partial and near complete inhibition by certain amino acids
CE Mogensen, K Sølling 		Scandinavian Journal of Clinical & Laboratory Investigation 1977
RELATION BETWEEN ENDEMIC (BALKAN) NEPHROPATHY AND URINARY-TRACT TUMOURS
TA Sattler, TS Dimitrov, PW Hall 		The Lancet 1977
Purification and properties of urinary alkaline ribonucleases from patients with nephrotic syndrome
M Yamanaka, K Akagi, K Murai, N Hirao, S Fujimi, T Omae 		Clinica Chimica Acta 1977
Serum β2-microglobulin in controls and cancer patients
C Teasdale, AM Mander, R Fifield, JW Keyser, RG Newcombe, LE Hughes 		Clinica Chimica Acta 1977
β 2 Microglobulinuria in a Patient with Nephrotoxicity Secondary to Mercuric Chloride Ingestion
AJ Pesce, I Hanenson, K Sethi 		Clinical Toxicology 1977
Urinary excretion of albumin and β 2 -microglobulin in a population from an area where Balkan nephropathy is endemic
FA Karlsson, R Lenkei 		Scandinavian Journal of Clinical & Laboratory Investigation 1977
Chemical characterization of human factor B of the alternate pathway of complement activation
B Curman, L Sandbert-Tragardh, PA Peterson 		Biochemistry 1977
Evaluation of different urinary proteins excreted after occupational Cd exposure
H Lars, K Tord, V Olof 		International Archives of Occupational and Environmental Health 1977
The effect of short-term glucagon infusion on kidney function in normal man
, J Noer, H Kehlet, CE Mogensen, PA Svendsen, L Heding 		Diabetologia 1977
Renal handling of Zn-alpha2-glycoprotein as compared with that of albumin and the retinol-binding protein
R Ekman, BG Johansson, U Ravnskov 		Journal of Clinical Investigation 1976
β2 -Microglobulin on the cell surface Specificity of inhibition of the mixed leukocyte reaction and mitogenic properties of antibodies against the two HLA antigen polypeptide chains
L Östberg, JB Lindblom, PA Peterson 		European Journal of Immunology 1976
Permeability of the blood–cerebrospinal fluid barrier to plasma proteins during foetal and perinatal life
M Adinolfi, SE Beck, SA Haddad, MJ Seller 		Nature 1976
The Urinary Excretion of Ten plasma proteins in Long-term Renal Transplant Patients
L Hemmingsen, H Jensen, P Skaarup 		Acta Medica Scandinavica 1976
LOW MOLECULAR WEIGHT PROTEINURIA AND SLIGHT HYPERLIPOPROTEINEMIA IN THREE MENTALLY RETARDED BROTHERS
R Eksmyr, G Fex, S Jagell, BG Johansson, U Ravnskov, G Samuelson 		Acta Paediatrica 1976
Comparison of radio-immunoassay and lymphocytotoxicity inhibition techniques for the determination of β2 microglobulin
C Vincent, JP Revillard 		Journal of Immunological Methods 1976
Urinary protein excretion in early infancy
FA Karlsson, K Hellsing 		The Journal of Pediatrics 1976
Isolation and partial characterization of a porcine low molecular weight protein occurring in plasma and urine
U Ravnskov, BG Johansson 		International Journal of Biochemistry 1976
A solid-phase radioimmunoassay for human β3-microglobulin
N Taniguchi, M Tanaka, K Kobayashi, I Matsuda, H Ohno, T Sato, E Takakuwa 		Clinica Chimica Acta 1976
Mechanism of Increased Renal Clearance of Amylase/Creatinine in Acute Pancreatitis
SG Johnson, CJ Ellis, MD Levitt 		New England Journal of Medicine 1976
The effect of metabolic regulation on microvascular permeability to small and large molecules in short-term juvenile diabetics
, I Noer, T Deckert, , SL Nielsen, J Lyngse, CE Mogensen, M Rrth, PA Svendsen, J Trap-Jensen, NA Lassen 		Diabetologia 1976
INCREASED URINARY EXCRETION OF ALBUMIN, LIGHT CHAINS, AND β2-MUCROGLOBULIN AFTER INTRAVENOUS ARGININE ADMINISTRATION IN NORMAL MAN
CE Mogensen, E Vittinghus, K Slling 		The Lancet 1975
Independent expression of the two HL-A antigen polypeptide chains
L Ostberg, L Rask, K Nilsson, PA Peterson 		European Journal of Immunology 1975
Evolutionary relationship between immunoglobulins and transplantation antigens
PA Peterson, L Rask, K Sege, L Klareskog, H Anundi, L Ostberg 		Proceedings of the National Academy of Sciences 1975
Evaluation of quantitative methods for determination of protein in urine
N Borg, L Hemmingsen, P Skaarup 		Clinica Chimica Acta 1975
A Study of the Low Molecular Weight Urinary Protein
J Tadano 		1975
Renal Handling of β 2 -Microglobulin in Experimental Renal Disease
A Fredriksson 		Scandinavian Journal of Clinical & Laboratory Investigation 1975
Radioimmunoassay of β 2 -Microglobulin
T Plesner, BN Pedersen, T Boenisch 		Scandinavian Journal of Clinical & Laboratory Investigation 1975
Renal Protein Metabolism in Obstructive Uropathy
L Novakovic, PW Hall, L Persky 		The Journal of Urology 1975
The excretion of proinsulin and insulin in urine
L Constan, M Mako, D Juhn, AH Rubenstein 		Diabetologia 1975
?2-mikroglobulin bei gesunden und nierenkranken Kindern
D Gekle, J Kult, H Httig, A Heidland 		European Journal of Pediatrics 1975
Analysis of Proteinuria in Health and Disease Using Sodium Dodecyl Sulphate–Acrylamide Gel Electrophoresis
JC Mulli, L Balant, M Giromini, J Fabre 		European Journal of Clinical Investigation 1974
Analysis of Proteinuria in Health and Disease Using Sodium Dodecyl Sulphate-Acrylamide Gel Electrophoresis
JC Mulli, L Balant, M Giromini, J Fabre 		European Journal of Clinical Investigation 1974
Structure, Evolution and Significance of beta2-Microglobulin
BA Cunningham, I Berggard 		Immunological Reviews 1974
Production of beta2-Microglobulin by Normal and Malignant Human Cell Lines and Peripheral Lymphocytes
K Nilsson, PE Evrin, KI Welsh 		Immunological Reviews 1974
Subunit structure of HL-A antigens on cell surface
L Östberg, JB Lindblom, PA Peterson 		Nature 1974
Intralysosomal digestion of lysozyme in renal proximal tubule cells
EI Christensen, AB Maunsbach 		Kidney International 1974
β2-Microglobulin on the Cell Surface. Relationship to HL-A Antigens and the Mixed Leucocyte Culture Reaction
JB Lindblom, LA ÖStberg, PE Peterson 		Tissue Antigens 1974
INCREASED URINARY ALBUMIN-EXCRETION RATE IN BENIGN ESSENTIAL HYPERTENSION
HH Parving, CE Mogensen, HÆ Jensen, PE Evrin 		The Lancet 1974
Highly purified papain-solubilized HL-A antigens contain beta2-microglobulin
PA Peterson, L Rask, JB Lindblom 		Proceedings of the National Academy of Sciences 1974
Physical-chemical properties of β2-microglobulin
FA Karlsson 		Immunochemistry 1974
Epidemiological Survey of Workers Exposed to Cadmium
RR Lauwerys, JP Buchet, HA Roels, J Brouwers, D Stanescu 		Archives of Environmental Health An International Journal 1974
Urinary protein analysis with sodium dodecylsulfate polyacrylamide gel electrophoresis — a comparison with other analytical techniques
L Balant, JC Mulli, J Fabre 		Clinica Chimica Acta 1974
Erbliche Defekte des Kohlenhydrat-, Aminosäuren- und Proteinstoffwechsels
W Barthelmai, HJ Bremer, H Cleve, A Doenicke, P Durand, ER Froesch, H Ghadimi, R Grüttner, WH Hitzig, S Hollmann, A Holzel, JK Lloyd, M Nyman, H Ott, W von Petrykowski, E Rossi, A Sass-Kortsak, JW Spranger, L Stengel-Rukowski, U Willenbockel, OH Wolff, F Linneweh 		1974
Structure and Function of Plasma Proteins
AC Allison 		1974
Isolation ofβ 2-microglobulin from the urine of patients with itai-itai (Ouch-ouch) disease
M Ohsawa, M Kimura 		Experientia 1973
Complete amino acid sequence of β 2 -microglobulin
BA Cunningham, JL Wang, I Berggard, PA Peterson 		Biochemistry 1973
Contemporary Topics in Molecular Immunology
RA Reisfeld, WJ Mandy 		1973
Lysozymuria and acute disorders of renal function
JF Harrison, RW Parker, KL Silva 		Journal of clinical pathology 1973
Combination of Specific Antibodies with the Human Vitamin A-transporting Protein Complex
A Vahlquist, PA Peterson 		The Journal of biological chemistry 1973
Composition and Variation of the Gel Electrophoretic Fractions of Plasma, Cerebrospinal Fluid and Urine
CB Laurell 		Scandinavian Journal of Clinical & Laboratory Investigation 1972
Metabolism of the Vitamin-A-Transporting Protein Complex: Turnover of Retinol-Binding Protein, Prealbumin and Vitamin A in a Primate (Macaca Irus)
A Vahlquist 		Scandinavian Journal of Clinical & Laboratory Investigation 1972
Renal Extraction of β2-Microglobulin
U Ravnskov, BG Johansson, J Göthlin 		Scandinavian Journal of Clinical & Laboratory Investigation 1972
The Serum Levels and Urinary Excretion of β2-Microglobulin in Apparently Healthy Subjects
PE Evrin, L Wibell 		Scandinavian Journal of Clinical & Laboratory Investigation 1972
Increased Urinary Clearance for Albumin,β2-Microglobulin, Insulin and Luteinizing Hormone following Surgical or Accidental Trauma
L Wide, L Thorén 		Scandinavian Journal of Clinical & Laboratory Investigation 1972
The Serum Level and Urinary Excretion of α2-Microglobulin, β2-Microglobulin and Lysozyme in Renal Disease
BG Johansson, U Ravnskov 		Scandinavian Journal of Urology and Nephrology 1972
A low molecular weight protein (β2-microglobulin) and renal disease in spinal cord injury patients
R Lindan, RS Post, GM Bernier, R Salzar 		Paraplegia 1972
Comparative studies on the vitamin A transporting protein complex in human and cynomolgus plasma
A Vahlquist, PA Peterson 		Biochemistry 1972
EFFECT OF STANDING ON PROTEINURIA IN RENAL DISEASE
BK Sharma, V Gandhi, VK Pillay, EC Smith, G Dunea 		The Lancet 1971
Urinary Albumin Excretion in Early and Long-Term Juvenile Diabetes
CE Mogensen 		Scandinavian Journal of Clinical & Laboratory Investigation 1971
Demonstration in Serum of two Physiological Forms of the Human Retinol Binding Protein
PA Peterson 		European Journal of Clinical Investigation 1971
Isolation of the Human Retinol Binding Protein by Affinity Chromatography
A Vahlquist, SF Nilsson, PA Peterson 		European Journal of Biochemistry 1971
Radioimmunoassay of β2-Microglobulin in Human Biological Fluids
PE Evrin, PA Peterson, L Wide, I Berggard 		Scandinavian Journal of Clinical & Laboratory Investigation 1971
Urinary Immunoglobulin Components in Normal, Tubular, and Glomerular Proteinuria: Quantities and Characteristics of Free Light Chains, IgG, IgA, and Fcγ Fragment
PA Peterson, I Berggård 		European Journal of Clinical Investigation 1971
Studies on the Interaction Between Prealbumin, Retinol-binding Protein, and Vitamin A
PA Peterson 		The Journal of biological chemistry 1971
Isolation and Partial Characterization of a Human Vitamin D-binding Plasma Protein
PA Peterson 		The Journal of biological chemistry 1971
The Subunit Structure of Human Thyroxine-binding Prealbumin
L Rask, PA Peterson, SF Nilsson 		The Journal of biological chemistry 1971
Isolation and Properties of a Human Retinol-transporting Protein
PA Peterson, I Berggård 		The Journal of biological chemistry 1971
Radioimmunoassay for Urinary Albumin Using a Single Antibody
DW Miles, CE Mogensen, HJ Gundersen 		Scandinavian Journal of Clinical & Laboratory Investigation 1970
THE LOWE SYNDROME
L Hambræus, G Pallisgaard, P Kildeberg 		Acta Paediatrica 1970
Proteinuria in renal disease
EL Becker 		Bulletin of the New York Academy of Medicine 1970
Pediatric renal disease
AM Robson, CB Manley 		Current Problems in Pediatrics 1970
Protides of the Biological Fluids
PA Small, RH Waldman 		Protides of the Biological Fluids 1969
The Plasma Proteins
ML Petermann 		The Plasma Proteins 1960

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