Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of β2-microglobulin, albumin, and total protein
Per A. Peterson, … , Per-Eric Evrin, Ingemar Berggård
Per A. Peterson, … , Per-Eric Evrin, Ingemar Berggård
Published July 1, 1969
Citation Information: J Clin Invest. 1969;48(7):1189-1198. https://doi.org/10.1172/JCI106083.
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Research Article

Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of β2-microglobulin, albumin, and total protein

Abstract

A low molecular weight β2-globulin (β2-microglobulin), albumin, and total protein were measured in concentrated 24-hr urine specimens from 20 healthy subjects and 30 patients with clinical proteinuria of glomerular or tubular type. Classification of proteinuria was made on the basis of clinical diagnosis and size distribution of urinary proteins after gel chromatography. The molecular radii (Stokes' radii) of β2-microglobulin and albumin, estimated by gel chromatography, were 15 A and 35 A.

Authors

Per A. Peterson, Per-Eric Evrin, Ingemar Berggård

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