A method is described for the measurement of total body exchangeable oxygen stores (TBO2). It is based on the dilution of the stable oxygen isotope, 18O2, by the body exchangeable oxygen stores under circumstances in which 18O2 steady-state equilibrium was evaluated simultaneously for both arterial and venous blood compartments. After evaluation of several simplifying assumptions, TBO2 values in dog, normal man, and anemic patients were measured. The magnitude of the exchangeable nonlung oxygen stores was 11.0 ± 3.1 ml/kg (SD) in 5 dogs, 11.9 ± 2.1 ml/kg in 10 normal subjects, and 7.0 ± 1.6 ml/kg in 8 patients with severe anemia (hematocrits of 25% or less).
Carroll E. Cross, Bernard S. Packer, Michael Altman, J. Bernard L. Gee, H. Victor Murdaugh Jr., Eugene D. Robin
Title and authors | Publication | Year |
---|---|---|
The experience of drowning.
Tipton M, Montgomery H |
Medico-Legal Journal | 2021 |
A model of oxygen isotope fractionation in body water of large mammals
JD Bryant, PN Froelich |
Geochimica et Cosmochimica Acta | 1995 |
Oxygen transport in low cardiac output states
JT Fahey, G Lister |
Journal of Critical Care | 1987 |
Prolonged diving and recovery in the freshwater turtle, Pseudemys scripta—II magnitude of depression of O2 requirements and the relation to body O2 stores
M Caligiuri, ED Robin, AJ Hance, DA Robin, N Lewiston, J Theodore |
Comparative Biochemistry and Physiology Part A: Physiology | 1981 |
Alterations in Distribution of Blood Flow to the Lung's Diffusion Surfaces During Exercise
CE Cross, H Gong, CJ Kurpershoek, JR Gillespie, RW Hyde |
Journal of Clinical Investigation | 1973 |
Oxygen Transport in Man
CA Finch, C Lenfant |
New England Journal of Medicine | 1972 |