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Gerald I. Shulman
Published January 15, 2000
Citation Information: J Clin Invest. 2000;106(2):171-176. https://doi.org/10.1172/JCI10583.
Citation Information: J Clin Invest. 2000;106(2):171-176. https://doi.org/10.1172/JCI10583.
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Citations to this article (1984)
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Inhibition of Lipid Accumulation in Skeletal Muscle and Liver Cells: A Protective Mechanism of Bilirubin Against Diabetes Mellitus Type 2
CA Hana, EM Klebermass, T Balber, M Mitterhauser, R Quint, Y Hirtl, A Klimpke, S Somloi, J Hutz, E Sperr, P Eder, J Jašprová, P Valášková, L Vítek, E Heiss, KH Wagner |
Frontiers in pharmacology | 2021 |
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SIRT1 functional polymorphisms (rs12778366, rs3758391) as genetic biomarkers of susceptibility to type 2 diabetes mellitus in Iranians: a case-control study and computational analysis
MB Sadeghi, A Nakhaee, R Saravani, MH Sadeghi, S Sargazi, MH Nia |
International Journal of Diabetes in Developing Countries | 2021 |
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Association among Neck Circumference and Percent Body Fat with Fasting Blood Glucose in Obese Female College Students
FF Dieny, I Indartiningsih, N Nuryanto, A Rahadiyanti |
2021 | |
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Turnover rate of coenzyme A in mouse brain and liver
L Orsatti, MV Orsale, P di Pasquale, A Vecchi, F Colaceci, A Ciammaichella, I Rossetti, F Bonelli, K Baumgaertel, K Liu, D Elbaum, E Monteagudo, RM Luque |
PloS one | 2021 |
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Involvement of miR-3180-3p and miR-4632-5p in palmitic acid-induced insulin resistance
E Tashiro, Y Nagasawa, S Itoh, M Imoto |
Molecular and Cellular Endocrinology | 2021 |
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IL-6 Reduces Mitochondrial Replication, and IL-6 Receptors Reduce Chronic Inflammation in NAFLD and Type 2 Diabetes
D Skuratovskaia, A Komar, M Vulf, HV Quang, E Shunkin, L Volkova, N Gazatova, P Zatolokin, L Litvinova |
International journal of molecular sciences | 2021 |
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Liver-specific dysregulation of clock-controlled output signal impairs energy metabolism in liver and muscle
T Matsumura, Y Ohta, A Taguchi, S Hiroshige, Y Kajimura, N Fukuda, K Yamamoto, H Nakabayashi, R Fujimoto, A Yanai, K Shinoda, K Watanabe, Y Mizukami, K Kanki, G Shiota, Y Tanizawa |
Biochemical and Biophysical Research Communications | 2021 |
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Anti-Diabetic Activity of Heuksoojeongchal Bran Prethanol Extract in HFD/STZ-Induced Diabetic Mice
JR Ham, MJ Lee, HI Lee, HJ Lee, HY Kim, WD Seo, YJ Son, MK Lee |
Journal of the Korean Society of Food Science and Nutrition | 2021 |
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Phosphorylated and O-GlcNAc Modified IRS-1 (Ser1101) and -2 (Ser1149) Contribute to Human Diabetes Type II
A Kaleem, S Javed, N Rehman, R Abdullah, M Iqtedar, MN Aftab, DC Hoessli, IU Haq |
Protein and peptide letters | 2021 |
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Fatty kidney disease: The importance of ectopic fat deposition and the potential value of imaging
C Mende, D Einhorn |
Journal of Diabetes | 2021 |
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Combination therapy with Exendin-4 and islet transplantation as a synergistic treatment for diabetic nephropathy in rats
Z Xie, Z Chen, J Chen |
Life Sciences | 2021 |
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Integrated metabolomics analysis of the effect of PPARδ agonist GW501516 on catabolism of BCAAs and carboxylic acids in diabetic mice
L Xiang, J Nie, L Wang, Y Wang, J Shi, J Wei, CW Lau, Z Cai, Y Huang |
Chinese Chemical Letters | 2021 |
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The effects of Zinc-Methionine on glucose metabolism and insulin resistance during late pregnancy in ewes
M Sadegzadeh-Sadat, E Anassori, H Khalilvandi-Behroozyar, S Asri-Rezaei |
Domestic Animal Endocrinology | 2021 |
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Taurine ameliorates axonal damage in sciatic nerve of diabetic rats and high glucose exposed DRG neuron by PI3K/Akt/mTOR-dependent pathway
M Zhang, X Shi, M Luo, Q Lan, H Ullah, C Zhang, S Li, X Chen, Y Wang, F Piao |
Amino Acids | 2021 |
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Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance
L Wong, JF Glatz, S Wang, IM Geraets, S Vanherle, A van den Wijngaard, H Brunner, JJ Luiken, M Nabben |
Prostaglandins, leukotrienes, and essential fatty acids | 2021 |
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EFFECTS OF EXERCISE TYPE AND INTENSITY ON VISFATIN AND THE METABOLIC SYNDROME IN OBESITY
J Lee |
Revista Brasileira de Medicina do Esporte | 2021 |
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Handgrip and sex-specific cardiometabolic risk factors in Hispanic/Latino migrant farmworkers
A Raed, J Bilz, M Cortez-Cooper, L Young, L Chen, P Cromer, H Zhu, A Mazzoli, S Parikh, J Bhagatwala, Y Dong, Z Sun, D Layman, Y Dong |
Scientific Reports | 2021 |
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Correlation of gut Firmicutes/Bacteroidetes ratio with fibrosis and steatosis stratified by body mass index in patients with non-alcoholic fatty liver disease
CO JASIRWAN, A MURADI, I HASAN, M SIMADIBRATA, I RINALDI |
Bioscience of Microbiota, Food and Health | 2021 |
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Computational, chemical profiling and biochemical evaluation of antidiabetic potential of Parkia biglobosa stem bark extract in type 2 model of rats
SO Oyedemi, K Eze, OA Aiyegoro, RC Ibeh, GC Ikechukwu, SS Swain, E Ejiofor, BO Oyedemi |
Journal of Biomolecular Structure and Dynamics | 2021 |
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Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement of mitochondrial biogenesis – Possible implication in pharmacotherapy
N Bourebaba, K Kornicka-Garbowska, K Marycz, L Bourebaba, A Kowalczuk |
Mitochondrion | 2021 |
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IL-6 Reduces Mitochondrial Replication, and IL-6 Receptors Reduce Chronic Inflammation in NAFLD and Type 2 Diabetes.
Skuratovskaia D, Komar A, Vulf M, Quang HV, Shunkin E, Volkova L, Gazatova N, Zatolokin P, Litvinova L |
International journal of molecular sciences | 2021 |
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Association between Coronary Artery Spasm and the risk of incident Diabetes: A Nationwide population-based Cohort Study.
Hung MJ, Chang NC, Hu P, Chen TH, Mao CT, Yeh CT, Hung MY |
International journal of medical sciences | 2021 |
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Fatty kidney disease: The importance of ectopic fat deposition and the potential value of imaging.
Mende C, Einhorn D |
Journal of Diabetes | 2021 |
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Handgrip and sex-specific cardiometabolic risk factors in Hispanic/Latino migrant farmworkers.
Raed A, Bilz J, Cortez-Cooper M, Young L, Chen L, Cromer P, Zhu H, Mazzoli A, Parikh S, Bhagatwala J, Dong Y, Sun Z, Layman D, Dong Y |
Scientific Reports | 2021 |
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Turnover rate of coenzyme A in mouse brain and liver.
Orsatti L, Orsale MV, di Pasquale P, Vecchi A, Colaceci F, Ciammaichella A, Rossetti I, Bonelli F, Baumgaertel K, Liu K, Elbaum D, Monteagudo E |
PloS one | 2021 |
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Effect of sakuranin on carbohydrate-metabolizing enzyme activity modifications in streptozotocin-nicotinamide-induced diabetic wistar rats.
Elsadek MF, Ahmed BM |
Saudi Journal of Biological Sciences | 2021 |
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LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1
W Gui, WF Zhu, Y Zhu, S Tang, F Zheng, X Yin, X Lin, H Li |
Cell Communication and Signaling | 2020 |
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Targeting the Liver‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice
IL Paraiso, JS Revel, J Choi, CL Miranda, P Lak, C Kioussi, G Bobe, AF Gombart, J Raber, CS Maier, JF Stevens |
Molecular Nutrition & Food Research | 2020 |
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Insulin Resistance in Osteoarthritis: Similar Mechanisms to Type 2 Diabetes Mellitus
EV Tchetina, GA Markova, EP Sharapova |
Journal of nutrition and metabolism | 2020 |
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Sarcopenic Obesity, Insulin Resistance, and Their Implications in Cardiovascular and Metabolic Consequences
S Hong, KM Choi |
International journal of molecular sciences | 2020 |
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A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance
K Lyu, Y Zhang, D Zhang, M Kahn, KW ter Horst, MR Rodrigues, RC Gaspar, SM Hirabara, PK Luukkonen, S Lee, S Bhanot, J Rinehart, N Blume, MG Rasch, MJ Serlie, JS Bogan, GW Cline, VT Samuel, GI Shulman |
Cell Metabolism | 2020 |
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Mechanisms of muscle insulin resistance and the cross‐talk with liver and adipose tissue
SC Rosa, N Nayak, AM Caymo, JW Gordon |
Physiological Reports | 2020 |
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Childhood obesity and the associated rise in cardiometabolic complications
S Caprio, N Santoro, R Weiss |
Nature metabolism | 2020 |
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Basal insulin ameliorates post-breakfast hyperglycemia via suppression of post-breakfast proinsulin/C-peptide ratio and fasting serum free fatty acid levels in patients with type 2 diabetes
K Ogiso, N Koriyama, T Obo, A Tokito, Y Nishio |
Diabetology International | 2020 |
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Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes
F Zatterale, M Longo, J Naderi, GA Raciti, A Desiderio, C Miele, F Beguinot |
Frontiers in physiology | 2020 |
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Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications
P Sangwung, KF Petersen, GI Shulman, JW Knowles |
Endocrinology | 2020 |
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A MicroRNA Linking Human Positive Selection and Metabolic Disorders
L Wang, N Sinnott-Armstrong, A Wagschal, AR Wark, JP Camporez, RJ Perry, F Ji, Y Sohn, J Oh, S Wu, J Chery, BN Moud, A Saadat, SN Dankel, G Mellgren, DS Tallapragada, SM Strobel, MJ Lee, R Tewhey, PC Sabeti, A Schaefer, A Petri, S Kauppinen, RT Chung, A Soukas, J Avruch, SK Fried, H Hauner, RI Sadreyev, GI Shulman, M Claussnitzer, AM Näär |
Cell | 2020 |
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Celastrol alleviates metabolic disturbance in high‐fat diet‐induced obese mice through increasing energy expenditure by ameliorating metabolic inflammation
X Yang, F Wu, L Li, EC Lynch, L Xie, Y Zhao, K Fang, J Li, J Luo, L Xu, X Zou, F Lu, G Chen |
Phytotherapy research : PTR | 2020 |
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Obesity and COVID-19: Molecular Mechanisms Linking Both Pandemics
A Ritter, NN Kreis, F Louwen, J Yuan |
International journal of molecular sciences | 2020 |
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Development of novel human in vitro vascularized adipose tissue model with functional macrophages
O Huttala, JR Sarkanen, M Mannerström, T Toimela, T Heinonen, T Ylikomi |
Cytotechnology | 2020 |
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Computational analysis of single nucleotide polymorphisms (SNPs) in PPAR gamma associated with obesity, diabetes and cancer
A Stalin, D Lin, JJ Princy, Y Feng, H Xiang, S Ignacimuthu, Y Chen |
Journal of Biomolecular Structure and Dynamics | 2020 |
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One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension
L Bilet, E Phielix, T van de Weijer, A Gemmink, M Bosma, E Moonen-Kornips, JA Jorgensen, G Schaart, D Zhang, K Meijer, M Hopman, MK Hesselink, DM Ouwens, GI Shulman, VB Schrauwen-Hinderling, P Schrauwen |
Diabetologia | 2020 |
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Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference
JD Song, TC Alves, DE Befroy, RJ Perry, GF Mason, XM Zhang, A Munk, Y Zhang, D Zhang, GW Cline, DL Rothman, KF Petersen, GI Shulman |
Cell Metabolism | 2020 |
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Mitochondrial Dysfunction in Obesity and Reproduction
M Das, C Sauceda, NJ Webster |
Endocrinology | 2020 |
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Lipid alterations in the skeletal muscle tissues of mice after weight regain by feeding a high-fat diet using nanoflow ultrahigh performance liquid chromatography-tandem mass spectrometry
JY Eum, GB Lee, SS Yi, IY Kim, JK Seong, MH Moon |
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences | 2020 |
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Muscle Lipid Droplets: Cellular Signaling to Exercise Physiology and Beyond
JT Seibert, CP Najt, TD Heden, DG Mashek, LS Chow |
Trends in endocrinology and metabolism: TEM | 2020 |
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Recent Updates on Obesity Treatments: Available Drugs and Future Directions
NR Dragano, J Fernø, C Diéguez, M López, E Milbank |
Neuroscience | 2020 |
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Reprint of: Recent Updates on Obesity Treatments: Available Drugs and Future Directions
NR Dragano, J Fernø, C Diéguez, M López, E Milbank |
Neuroscience | 2020 |
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Dietary natural products as epigenetic modifiers in aging-associated inflammation and disease
LW Evans, MS Stratton, BS Ferguson |
Natural Product Reports | 2020 |
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Effect of growth hormone on insulin signaling
R Sharma, JJ Kopchick, V Puri, VM Sharma |
Molecular and Cellular Endocrinology | 2020 |
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Complexity analysis and dynamic characteristics of EEG using MODWT based entropies for identification of seizure onset:
S Raghu, N Sriraam, Y Temel, SV Rao, AS Hegde, PL Kubben |
Journal of Biomedical Research | 2020 |
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Shared signaling pathways in Alzheimer’s and metabolic disease may point to new treatment approaches
J Suresh, IW Khor, P Kaur, HL Heng, F Torta, GS Dawe, ES Tai, NS Tolwinski |
The FEBS journal | 2020 |
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CD36 (SR-B2) as a Target to Treat Lipid Overload-Induced Cardiac Dysfunction
JF Glatz, JJ Luiken, M Nabben |
Journal of Lipid and Atherosclerosis | 2020 |
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Significance of bilayer-forming phospholipids for skeletal muscle insulin sensitivity and mitochondrial function
Grapentine S, Bakovic M |
Journal of Biomedical Research | 2020 |
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Hepatic dysfunction after spinal cord injury: A vicious cycle of central and peripheral pathology?
MT Goodus, DM McTigue |
Experimental Neurology | 2020 |
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Towards an Insulin Resistant Adipose Model on a Chip
N Tanataweethum, F Zhong, A Trang, C Lee, RN Cohen, A Bhushan |
Cellular and Molecular Bioengineering | 2020 |
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Insights from the clinical phenotype of subjects with Laron syndrome in Ecuador
J Guevara-Aguirre, C Bautista, C Torres, G Peña, C Guevara, C Palacios, A Guevara, AW Gavilanes |
Reviews in Endocrine and Metabolic Disorders | 2020 |
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Quantitative Fluxomics of Circulating Metabolites
S Hui, AJ Cowan, X Zeng, L Yang, T TeSlaa, X Li, C Bartman, Z Zhang, C Jang, L Wang, W Lu, J Rojas, J Baur, JD Rabinowitz |
Cell Metabolism | 2020 |
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Emerging Research in Science and Engineering Based on Advanced Experimental and Computational Strategies
F de Almeida La Porta, CA Taft |
2020 | |
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The Liver: Biology and Pathobiology
IM Arias, HJ Alter, JL Boyer, DE Cohen, DA Shafritz, SS Thorgeirsson, AW Wolkoff |
2020 | |
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Cd36 gene expression in adipose and hepatic tissue mediates the lipids accumulation in liver of obese rats with sucrose-induced hepatic steatosis
R Quintana-Castro, I Aguirre-Maldonado, I Soto-Rodríguez, RA Deschamps-Lago, P Gruber-Pagola, YK de Larrea, VE Juárez-Rivera, LE Ramos-Manuel, A Alexander-Aguilera |
Prostaglandins & Other Lipid Mediators | 2020 |
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Oral L-glutamine restores adenosine and glutathione content in the skeletal muscle and adipose tissue of insulin-resistant pregnant rats
KS Olaniyi, IW Sabinari, LA Olatunji |
Nutrition (Burbank, Los Angeles County, Calif.) | 2020 |
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Type 2 Diabetes Mellitus in Osteoarthritic Patients: Does Association Between Metabolic Impairments, Joint Destruction, and Pain Exist?
EV Chetina, GA Markova, EP Sharapova |
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry | 2020 |
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Pathway attenuation of fatty acid beta‐oxidation in the skeletal muscle of a type 2 diabetic mouse model
Y Zhou, Y Tan, G Hou, Y Ren, Y Deng, K Yan, Y Zhang, L Lin, X Lou, S Liu |
Rapid Communications in Mass Spectrometry | 2020 |
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Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2 × 2 factorial, randomised, crossover study in human individuals
AJ Hjelholt, E Charidemou, JL Griffin, SB Pedersen, A Gudiksen, H Pilegaard, N Jessen, N Møller, JO Jørgensen |
Diabetologia | 2020 |
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The obesity paradox and diabetes
G Gravina, F Ferrari, G Nebbiai |
Eating and weight disorders : EWD | 2020 |
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The visceral adiposity index is a predictor of incident nonalcoholic fatty liver disease: A population-based longitudinal study
T Okamura, Y Hashimoto, M Hamaguchi, A Obora, T Kojima, M Fukui |
Clinics and Research in Hepatology and Gastroenterology | 2020 |
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White sweet potato ameliorates hyperglycemia and regenerates pancreatic islets in diabetic mice
CK Shih, CM Chen, V Varga, LC Shih, PR Chen, SF Lo, LF Shyur, SC Li |
Food & Nutrition Research | 2020 |
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Macrovascular Complications of Type 2 Diabetes Mellitus
M Viigimaa, A Sachinidis, M Toumpourleka, K Koutsampasopoulos, S Alliksoo, T Titma |
Current vascular pharmacology | 2020 |
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Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide/Streptozotocin-Induced Wistar Diabetic Rats
AM Ali, MA Gabbar, SM Abdel-Twab, EM Fahmy, H Ebaid, IM Alhazza, OM Ahmed |
Oxidative medicine and cellular longevity | 2020 |
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d-allulose Ameliorates Metabolic Dysfunction in C57BL/KsJ-db/db Mice
D Lee, Y Han, EY Kwon, MS Choi |
Molecules (Basel, Switzerland) | 2020 |
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Diabetic neuropathy is associated with increased pain perception, low serum beta-endorphin and increase insulin resistance among Nigerian cohorts in Ekiti State
OO Akintoye, BV Owoyele, OA Fabunmi, TH Raimi, AA Oniyide, AO Akintoye, AJ Ajibare, DD Ajayi, GS Adeleye |
Heliyon | 2020 |
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Chrysoeriol ameliorates hyperglycemia by regulating the carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats
B Krishnan, AR Ganesan, R Balasubramani, DD Nguyen, SW Chang, S Wang, J Xiao, B Balasubramanian |
Food Science and Human Wellness | 2020 |
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Assessment of the protective and therapeutic effect of melatonin against thioacetamide‐induced acute liver damage
M Sayan, D Karabulut, S Özdamar |
Journal of Biochemical and Molecular Toxicology | 2020 |
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Rational design of a GLP-1/GIP/Gcg receptor triagonist to correct hyperglycemia, obesity and diabetic nephropathy in rodent animals
J Cui, A Shang, W Wang, W Chen |
Life Sciences | 2020 |
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Management of type 2 diabetes for prevention of cardiovascular disease. An expert opinion of the Italian Diabetes Society
R Napoli, G Formoso, S Piro, G Targher, A Consoli, F Purrello |
Nutrition, Metabolism, and Cardiovascular Diseases | 2020 |
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Equine Hematology, Cytology, and Clinical Chemistry
RM Walton, RL Cowell, AC Valenciano |
2020 | |
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Antibiotic affects the gut microbiota composition and expression of genes related to lipid metabolism and myofiber types in skeletal muscle of piglets
H Yan, B Yu, J Degroote, T Spranghers, NV Noten, M Majdeddin, MV Poucke, L Peelman, JD Vrieze, N Boon, I Gielen, SD Smet, D Chen, J Michiels |
BMC veterinary research | 2020 |
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Agmatine modulates anxiety and depression-like behaviour in diabetic insulin-resistant rats
M Kale, N Nimje, MM Aglawe, M Umekar, B Taksande, N Kotagale |
Brain Research | 2020 |
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Sodium acetate prevents nicotine-induced cardiorenal dysmetabolism through uric acid/creatine kinase-dependent pathway
OS Michael, CL Dibia, OA Soetan, OA Adeyanju, AL Oyewole, OO Badmus, CO Adetunji, AO Soladoye |
Life Sciences | 2020 |
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Night‐restricted feeding improves locomotor activity rhythm and modulates nutrient utilization to accelerate growth in rabbits
Y Guo, QJ Wang, KH Zhang, CY Yao, J Huang, Q Li, ZY Liu, Y Zhang, CH Shan, P Liu, MZ Wang, L An, JH Tian, ZH Wu |
The FASEB Journal | 2020 |
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Assessing insulin sensitivity and resistance in syndromes of severe short stature
J Guevara-Aguirre, E Teran, D Lescano, C Guevara, A Guevara, J Saavedra, P Procel, C Wasserfall, AW Gavilanes |
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society | 2020 |
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Study on the mechanism of Gegen Qinlian Decoction for treating type II diabetes mellitus by integrating network pharmacology and pharmacological evaluation
X Xu, L Niu, Y Liu, M Pang, W Lu, C Xia, Y Zhu, B Yang, Q Wang |
Journal of Ethnopharmacology | 2020 |
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Synthesis and Evaluation of Dapagliflozin Ester Prodrugs with Improved Hygroscopicity and Thermal Stability
SY Sung, YN Chae, DY Lee, KM Kim, EJ Kim, JH Han, W Kim, SH Yoon |
Letters in drug design & discovery | 2020 |
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The role of the fibrinolytic system in female reproductive disorders and depression
S Hoirisch-Clapauch, B Brenner |
2020 | |
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Associations between Relative Handgrip Strength and Incidence of Type 2 Diabetes Mellitus in Middle-aged and Older adults: Finding from the Korean Genome and Epidemiology Study
ES Yoon, SH Park |
Exercise Science | 2020 |
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Surrogate indexes of insulin resistance and risk of metabolic syndrome in non-Hispanic White, non-Hispanic Black and Mexican American
IS Okosun, B Okosun, R Lyn, C Airhihenbuwa |
Diabetes & Metabolic Syndrome: Clinical Research & Reviews | 2020 |
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Estimated insulin sensitivity in Type 1 diabetes adults using clinical and research biomarkers
AS Januszewski, N Sachithanandan, G Ward, CS Karschimkus, DN O'Neal, AJ Jenkins |
Diabetes Research and Clinical Practice | 2020 |
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Effects of 10-week combined training on lipid metabolic regulatory hormones and metabolic syndrome index according to exercise dose in obese male college students
S Li, JY Kim, YJ Sim |
Journal of Exercise Rehabilitation | 2020 |
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Study of the diacylglycerol composition in the liver and serum of mice with prediabetes and diabetes using MeV TOF-SIMS
MP Hadžija, Z Siketić, M Hadžija, M Barac, IB Radović |
Diabetes Research and Clinical Practice | 2020 |
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Relationship of metabolic syndrome defined by IDF or revised NCEP ATP III with glycemic control among Malaysians with Type 2 Diabetes
R Saif-Ali, NA Kamaruddin, M AL-Habori, SA Al-Dubai, WZ Ngah |
Diabetology & metabolic syndrome | 2020 |
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Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance
JJ Luiken, M Nabben, D Neumann, JF Glatz |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2020 |
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In Vitro-Generated Hypertrophic-Like Adipocytes Displaying PPARG Isoforms Unbalance Recapitulate Adipocyte Dysfunctions In Vivo
M Aprile, S Cataldi, C Perfetto, MR Ambrosio, P Italiani, R Tatè, M Blüher, A Ciccodicola, V Costa |
Cells | 2020 |
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Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance
Y Liu, HY Wang, J Shao, JL Zaro, WC Shen |
Scientific Reports | 2020 |
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PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation
HC Chien, PL Greenhaff, D Constantin-Teodosiu |
International journal of molecular sciences | 2020 |
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Phosphatidylinositol 4-kinase IIIβ mediates contraction-induced GLUT4 translocation and shows its anti-diabetic action in cardiomyocytes
A Sun, OS Papur, E Dirkx, L Wong, T Sips, S Wang, A Strzelecka, M Nabben, JF Glatz, D Neumann, JJ Luiken |
Cellular and Molecular Life Sciences | 2020 |
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Effects of 10-week combined training on lipid metabolic regulatory hormones and metabolic syndrome index according to exercise dose in obese male college students.
Li S, Kim JY, Sim YJ |
Journal of Exercise Rehabilitation | 2020 |
|
Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide/Streptozotocin-Induced Wistar Diabetic Rats.
Ali AM, Gabbar MA, Abdel-Twab SM, Fahmy EM, Ebaid H, Alhazza IM, Ahmed OM |
Oxidative medicine and cellular longevity | 2020 |
|
Correlation of gut Firmicutes/Bacteroidetes ratio with fibrosis and steatosis stratified by body mass index in patients with non-alcoholic fatty liver disease.
Jasirwan COM, Muradi A, Hasan I, Simadibrata M, Rinaldi I |
Bioscience of Microbiota, Food and Health | 2020 |
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Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges.
Dooghaie Moghadam A, Eslami P, Razavi-Khorasani N, Moazzami B, Zahedi-Tajrishi F, Farokhi E, Makhdoomi Sharabiani K, Mansour-Ghanaei A, Mehrvar A, Aghajanpoor Pasha M, Saeedi S, Iravani S |
Caspian Journal of Internal Medicine | 2020 |
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Diabetic neuropathy is associated with increased pain perception, low serum beta-endorphin and increase insulin resistance among Nigerian cohorts in Ekiti State.
Akintoye OO, Owoyele BV, Fabunmi OA, Raimi TH, Oniyide AA, Akintoye AO, Ajibare AJ, Ajayi DD, Adeleye GS |
Heliyon | 2020 |
|
Relationship of metabolic syndrome defined by IDF or revised NCEP ATP III with glycemic control among Malaysians with Type 2 Diabetes.
Saif-Ali R, Kamaruddin NA, Al-Habori M, Al-Dubai SA, Ngah WZW |
Diabetology & metabolic syndrome | 2020 |
|
d-allulose Ameliorates Metabolic Dysfunction in C57BL/KsJ-db/db Mice.
Lee D, Han Y, Kwon EY, Choi MS |
Molecules (Basel, Switzerland) | 2020 |
|
Antibiotic affects the gut microbiota composition and expression of genes related to lipid metabolism and myofiber types in skeletal muscle of piglets.
Yan H, Yu B, Degroote J, Spranghers T, Van Noten N, Majdeddin M, Van Poucke M, Peelman L, De Vrieze J, Boon N, Gielen I, Smet S, Chen D, Michiels J |
BMC veterinary research | 2020 |
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What lipodystrophies teach us about the metabolic syndrome
Jake P. Mann, David Savage |
Journal of Clinical Investigation | 2019 |
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Altered lipid fluxes and cell dynamics shape unfavorable fat patterns in obese girls
Jessica Nouws, Mark Fitch, Mariana M. Mata, Romy Kursawe, Deepak Narayan, Bridget Pierpont, Gerald I. Shulman, Marc K Hellerstein, Sonia Caprio |
Diabetes | 2019 |
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Emerging Pharmacological Targets for the Treatment of Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Type 2 Diabetes
L Goedeke, RJ Perry, GI Shulman |
Annual Review of Pharmacology and Toxicology | 2019 |
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Pathogenesis of Insulin Resistance and Atherogenic Dyslipidemia in Nonalcoholic Fatty Liver Disease
DH Akhtar, U Iqbal, LM Vazquez-Montesino, BB Dennis, A Ahmed |
Journal of Clinical and Translational Hepatology | 2019 |
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Insulin resistance and diabetes in hyperthyroidism: a possible role for oxygen and nitrogen reactive species
P Venditti, TT Reed, VM Victor, SD Meo |
Free Radical Research | 2019 |
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Mechanisms of Protective Effects of SGLT2 Inhibitors in Cardiovascular Disease and Renal Dysfunction
B Liu, Y Wang, Y Zhang, B Yan |
Current topics in medicinal chemistry | 2019 |
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Implications of resistin in type 2 diabetes mellitus and coronary artery disease: Impairing insulin function and inducing pro‐inflammatory cytokines
M Emamalipour, K Seidi, A JahanbanEsfahlan, R JahanbanEsfahlan |
Journal of Cellular Physiology | 2019 |
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Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes
HB Kwak, T Woodlief, T Green, J Cox, R Hickner, P Neufer, R Cortright |
International journal of environmental research and public health | 2019 |
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Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes
RC Meex, EE Blaak, LJ Loon |
Obesity reviews : an official journal of the International Association for the Study of Obesity | 2019 |
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Obesity and muscle‐macrophage crosstalk in humans and mice: A systematic review
S Rudrapatna, M Bhatt, KW Wang, R Bierbrier, PW Wang, L Banfield, W Elsheikh, ED Sims, D Peterson, L Thabane, MA Tarnopolsky, GR Steinberg, MC Samaan |
Obesity reviews : an official journal of the International Association for the Study of Obesity | 2019 |
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Mitochondria in Health and in Sickness
A Urbani, M Babu |
2019 | |
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Mitochondria in Health and in Sickness
A Urbani, M Babu |
2019 | |
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Mitochondria in Health and in Sickness
A Urbani, M Babu |
2019 | |
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Mitochondria in Health and in Sickness
A Urbani, M Babu |
2019 | |
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Mitochondria in Health and in Sickness
A Urbani, M Babu |
2019 | |
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Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity
S Masuda, Y Fujishima, N Maeda, Y Tsugawa-Shimizu, Y Nakamura, Y Tanaka, Y Obata, S Fukuda, H Nagao, S Kita, H Nishizawa, I Shimomura |
American journal of physiology. Endocrinology and metabolism | 2019 |
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De Novo Lipogenesis as a Source of Second Messengers in Adipocytes
WY Hsiao, DA Guertin |
Current Diabetes Reports | 2019 |
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A Study on Molecular Mechanisms of Adiposis Induced by Long-Term Treatment of High-Fat and High-Sucrose in C57BL/6J Mice
X Li, P Tu, M Umar, Q Liu, W Luo, X Yang, J Zhu, D Kong, M Li |
Physiological research / Academia Scientiarum Bohemoslovaca | 2019 |
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2-Aminoadipic acid (2-AAA) as a potential biomarker for insulin resistance in childhood obesity
HJ Lee, HB Jang, WH Kim, KJ Park, KY Kim, SI Park, HJ Lee |
Scientific Reports | 2019 |
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Role of Oleic Acid in the Gut-Liver Axis: From Diet to the Regulation of Its Synthesis via Stearoyl-CoA Desaturase 1 (SCD1)
E Piccinin, M Cariello, SD Santis, S Ducheix, C Sabbà, JM Ntambi, A Moschetta |
Nutrients | 2019 |
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Obesity as the Main Risk Factor for Metabolic Syndrome in Children.
Gepstein V, Weiss R |
Frontiers in Endocrinology | 2019 |
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Treatment With Naringenin Elevates the Activity of Transcription Factor Nrf2 to Protect Pancreatic β-Cells From Streptozotocin-Induced Diabetes in vitro and in vivo
R Rajappa, D Sireesh, MB Salai, KM Ramkumar, S Sarvajayakesavulu, SR Madhunapantula |
Frontiers in pharmacology | 2019 |
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Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone
NM Maalouf, JR Poindexter, B Adams-Huet, OW Moe, K Sakhaee |
Kidney International | 2019 |
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Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine-exposed rats
EO Dangana, OS Michael, TE Omolekulo, ED Areola, LA Olatunji |
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie | 2019 |
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Impact of maternal low-level cadmium exposure on glucose and lipid metabolism of the litter at different ages after weaning
A Jacquet, D Barbeau, J Arnaud, S Hijazi, F Hazane-Puch, F Lamarche, C Quiclet, K Couturier, E Fontaine, JM Moulis, C Demeilliers |
Chemosphere | 2019 |
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The polyherbal composition Gyeongshingangjeehwan 18 attenuates glucose intolerance and pancreatic steatosis in C57BL/6J mice on a high-fat diet
J Jang, Y Park, D Lee, H Lee, J Lim, SA Yoon, H Lee, J Ahn, S Jeong, SS Shin, M Yoon |
Journal of Ethnopharmacology | 2019 |
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The Release of Adipose Stromal Cells from Subcutaneous Adipose Tissue Regulates Ectopic Intramuscular Adipocyte Deposition
A Girousse, M Gil-Ortega, V Bourlier, C Bergeaud, Q Sastourné-Arrey, C Moro, C Barreau, C Guissard, J Vion, E Arnaud, JP Pradère, N Juin, L Casteilla, C Sengenès |
Cell Reports | 2019 |
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Dietary curcumin enhances insulin clearance in diet-induced obese mice via regulation of hepatic PI3K-AKT axis and IDE, and preservation of islet integrity
Y Kim, M Rouse, I González-Mariscal, JM Egan, JF OConnell |
Nutrition & Metabolism | 2019 |
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Identification of 1 H -pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors
Y Nam, D Hwang, N Kim, HS Seo, KB Selim, T Sim |
Journal of Enzyme Inhibition and Medicinal Chemistry | 2019 |
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Modeling the dynamics of glucose, insulin, and free fatty acids with time delay: The impact of bariatric surgery on type 2 diabetes mellitus
AL Murillo, J Li, C Castillo-Chavez |
Mathematical Biosciences and Engineering | 2019 |
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Effects of food restriction and/or aerobic exercise on the GLUT4 in type 2 diabetic male rats
H Dastbarhagh, M Kargarfard, H Abedi, E Bambaeichi, P Nazarali |
International journal of preventive medicine | 2019 |
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Metformin treatment affects adipocytokines secretion and lipid composition in adipose tissues of diet-induced insulin resistant rats
S Grycel, AR Markowski, HR Hady, P Zabielski, I Kojta, M Imierska, J Górski, AU Blachnio-Zabielska |
Nutrition (Burbank, Los Angeles County, Calif.) | 2019 |
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The influence of insulin resistance in the occurence of non-alcoholic fatty liver disease among first degree relatives of type 2 diabetes
A Hazim, D Purnamasari, KF Kalista, CR Lesmana, P Nugroho |
Diabetes & Metabolic Syndrome: Clinical Research & Reviews | 2019 |
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Experimental therapies targeting apolipoprotein C-III for the treatment of hyperlipidemia – spotlight on volanesorsen
D Milonas, K Tziomalos |
Expert Opinion on Investigational Drugs | 2019 |
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Influenza Virus Infections and Cellular Kinases
R Meineke, G Rimmelzwaan, H Elbahesh |
Viruses | 2019 |
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Heart failure among people with Type 2 diabetes mellitus: real-world data of 289 954 people from a diabetes database
D Stoyanova, B Stratmann, A Schwandt, N Heise, S Mühldorfer, HJ Ziegelasch, A Zimmermann, D Tschoepe, RW Holl |
Diabetic Medicine | 2019 |
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Gymnemic Acid Alleviates Type 2 Diabetes Mellitus and Suppresses Endoplasmic Reticulum Stress in Vivo and in Vitro
Y Li, M Sun, Y Liu, J Liang, T Wang, Z Zhang |
Journal of Agricultural and Food Chemistry | 2019 |
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Insulin Resistance: Childhood Precursors of Adult Disease
PS Zeitler, KJ Nadeau |
2019 | |
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Combination of mulberry leaf and oat bran possessed greater hypoglycemic effect on diabetic mice than mulberry leaf or oat bran alone
TH, P Wen, J Liu, XS Long, ST Liao, H Wu, YX Zou |
Journal of Functional Foods | 2019 |
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New molecular biomarkers in precise diagnosis and therapy of Type 2 diabetes
S Mandal |
Health and Technology | 2019 |
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Obesity as the Main Risk Factor for Metabolic Syndrome in Children
V Gepstein, R Weiss |
Frontiers in Endocrinology | 2019 |
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Retrospective Evaluation of an Online Diabetes Health Coaching Program: A Pilot Study
J Sarver, C Khambatta, R Barbaro, B Chavan, D Drozek |
American journal of lifestyle medicine | 2019 |
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Quercetin modulates hyperglycemia by improving the pancreatic antioxidant status and enzymes activities linked with glucose metabolism in type 2 diabetes model of rats: In silico studies of molecular interaction of quercetin with hexokinase and catalase
SO Oyedemi, G Nwaogu, CI Chukwuma, OT Adeyemi, MG Matsabisa, SS Swain, OA Aiyegoro |
Journal of Food Biochemistry | 2019 |
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Fatty Kidney Disease: A New Renal And Endocrine Clinical Entity? Describing the Role of the Kidney in Obesity, Metabolic Syndrome, and Type 2 Diabetes
CW Mende, D Einhorn |
Endocrine Practice | 2019 |
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The effects of two weeks high-intensity interval training on fasting glucose, glucose tolerance and insulin resistance in adolescent boys: a pilot study
EJ Cockcroft, B Bond, CA Williams, S Harris, SR Jackman, N Armstrong, AR Barker |
BMC Sports Science, Medicine and Rehabilitation | 2019 |
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New Insights into Bioactive Compounds of Traditional Chinese Medicines for Insulin Resistance Based on Signaling Pathways
J He, H Wang, J Vijg |
Chemistry & Biodiversity | 2019 |
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Hesperidin, a citrus flavonoid ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats
R Sundaram, E Nandhakumar, HH Banu |
Toxicology Mechanisms and Methods | 2019 |
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Recent Updates in Pharmacological Properties of Chitooligosaccharides
I Marmouzi, SM Ezzat, MM Salama, RM Merghany, AM Attar, AM EL-Desoky, SO Mohamed |
BioMed Research International | 2019 |
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Hepato-protective effects of Glossogyne tenuifolia in Streptozotocin-nicotinamide-induced diabetic rats on high fat diet
SM Asokan, RY Wang, TH Hung, WT Lin |
BMC complementary and alternative medicine | 2019 |
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Sonographic Assessment of Heel Pad Thickness in Patients With Poorly Controlled Diabetes
BE Udoh, BE Archibong, AE Egong |
Journal of Diagnostic Medical Sonography | 2019 |
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Suppression of Blue Light at Night Ameliorates Metabolic Abnormalities by Controlling Circadian Rhythms
N Nagai, M Ayaki, T Yanagawa, A Hattori, K Negishi, T Mori, TJ Nakamura, K Tsubota |
Investigative ophthalmology & visual science | 2019 |
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Reference Gene Optimization for Circadian Gene Expression Analysis in Human Adipose Tissue
JM White, MJ Piron, VR Rangaraj, EC Hanlon, RN Cohen, MJ Brady |
Journal of Biological Rhythms | 2019 |
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Azoramide improves mitochondrial dysfunction in palmitate-induced insulin resistant H9c2 cells
EN Okatan, Y Olgar, E Tuncay, B Turan |
Molecular and Cellular Biochemistry | 2019 |
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Silencing of GPR82 with Interference RNA Improved Metabolic Profiles in Rats with High Fructose Intake
R Romero-Nava, KA Aguayo-Cerón, A Ruiz-Hernández, F Huang, E Hong, A Aguilera-Mendez, SV Rauda |
Journal of Vascular Research | 2019 |
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Hepato-protective effects of Glossogyne tenuifolia in Streptozotocin-nicotinamide-induced diabetic rats on high fat diet.
Asokan SM, Wang RY, Hung TH, Lin WT |
BMC complementary and alternative medicine | 2019 |
|
Retrospective Evaluation of an Online Diabetes Health Coaching Program: A Pilot Study.
Sarver J, Khambatta C, Barbaro R, Chavan B, Drozek D |
American journal of lifestyle medicine | 2019 |
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Recent Updates in Pharmacological Properties of Chitooligosaccharides.
Marmouzi I, Ezzat SM, Salama MM, Merghany RM, Attar AM, El-Desoky AM, Mohamed SO |
BioMed Research International | 2019 |
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The effects of two weeks high-intensity interval training on fasting glucose, glucose tolerance and insulin resistance in adolescent boys: a pilot study.
Cockcroft EJ, Bond B, Williams CA, Harris S, Jackman SR, Armstrong N, Barker AR |
2019 | |
|
Circadian clocks and insulin resistance.
Stenvers DJ, Scheer FAJL, Schrauwen P, la Fleur SE, Kalsbeek A |
Nature reviews. Endocrinology | 2019 |
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Heart failure among people with Type 2 diabetes mellitus: real-world data of 289 954 people from a diabetes database.
Stoyanova D, Stratmann B, Schwandt A, Heise N, Mühldorfer S, Ziegelasch HJ, Zimmermann A, Tschoepe D, Holl RW |
Diabetic medicine : a journal of the British Diabetic Association | 2019 |
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Influenza Virus Infections and Cellular Kinases.
Meineke R, Rimmelzwaan GF, Elbahesh H |
Viruses | 2019 |
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Macrophage migration inhibitory factor (MIF) mediates the adverse metabolic action of the atypical antipsychotic therapy
Donghong Cui, Yanmin Peng, Chengfang Zhang, Zezhi Li, Yousong Su, Yadan Qi, Mengjuan Xing, Jia Li, Grace Kim, Kevin Su, Jinjie Xu, Meiti Wang, Wenhua Ding, Marta Piecychna, Lin Leng, Michiru Hirasawa, Kaida Jiang, Lawrence Young, Yifeng Xu, Dake Qi, Richard Bucala |
Journal of Clinical Investigation | 2018 |
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SURPLUS FAT INCREASES FAT OXIDATION AND HYPERINSULINAEMIA IN LIPODYSTROPHIC MICE
Amandine Girousse, Sam Virtue, Dan Hart, Antonio Vidal-Puig, Peter Murgatroyd, David Savage |
Molecular Metabolism | 2018 |
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Reduced Skeletal Muscle Phosphocreatine Concentration in Type 2 Diabetic Patients: A Quantitative Image-Based Phosphorus-31 MR Spectroscopy Study
EM Ripley, GD Clarke, V Hamidi, RA Martinez, FD Settles, C Solis, S Deng, M Abdul-Ghani, D Tripathy, RA DeFronzo |
American journal of physiology. Endocrinology and metabolism | 2018 |
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Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword
XY Qi, SL Qu, WH Xiong, O Rom, L Chang, ZS Jiang |
Cardiovascular Diabetology | 2018 |
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Mechanisms of Insulin Action and Insulin Resistance
MC Petersen, GI Shulman |
Physiological reviews | 2018 |
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Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents
DF Vatner, L Goedeke, JP Camporez, K Lyu, AR Nasiri, D Zhang, S Bhanot, SF Murray, CD Still, GS Gerhard, GI Shulman, VT Samuel |
Diabetologia | 2018 |
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Association between insulin resistance and the development of cardiovascular disease
V Ormazabal, S Nair, O Elfeky, C Aguayo, C Salomon, FA Zuñiga |
Cardiovascular Diabetology | 2018 |
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Role of Lipotoxicity and Contribution of the Renin-Angiotensin System in the Development of Polycystic Ovary Syndrome
A Connolly, S Leblanc, JP Baillargeon |
International Journal of Endocrinology | 2018 |
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Effect of supplementing chromium histidinate and picolinate complexes along with biotin on insulin sensitivity and related metabolic indices in rats fed a high-fat diet
C Orhan, O Kucuk, M Tuzcu, N Sahin, JR Komorowski, K Sahin |
Food Science & Nutrition | 2018 |
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AMPK
D Neumann, B Viollet |
2018 | |
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AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
|
AMPK
D Neumann, B Viollet |
2018 | |
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AMPK
D Neumann, B Viollet |
2018 | |
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Molecular pathways of nonalcoholic fatty liver disease development and progression
F Bessone, MV Razori, MG Roma |
Cellular and Molecular Life Sciences | 2018 |
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Adiponectin: A potential therapeutic target for metabolic syndrome
AA Ghadge, AA Khaire, AA Kuvalekar |
Cytokine & Growth Factor Reviews | 2018 |
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Increased Endothelin-1-Mediated Vasoconstrictor Tone in Human Obesity: Effects of Gut Hormones
F Schinzari, M Tesauro, C Cardillo |
Physiological research / Academia Scientiarum Bohemoslovaca | 2018 |
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A long-term mechanistic computational model of physiological factors driving the onset of type 2 diabetes in an individual
J Sarkar, G Dwivedi, Q Chen, IE Sheu, M Paich, CM Chelini, PM D'Alessandro, SP Burns, J DiStefano |
PloS one | 2018 |
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Exercise as ‘precision medicine’ for insulin resistance and its progression to type 2 diabetes: a research review
FJ DiMenna, AD Arad |
BMC Sports Science, Medicine and Rehabilitation | 2018 |
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The Aqueous Extract of Gynura divaricata (L.) DC. Improves Glucose and Lipid Metabolism and Ameliorates Type 2 Diabetes Mellitus
J Li, J Feng, H Wei, Q Liu, T Yang, S Hou, Y Zhao, B Zhang, C Yang |
Evidence-Based Complementary and Alternative Medicine | 2018 |
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Heart Failure With Preserved Ejection Fraction in Diabetes: Mechanisms and Management
P Meagher, M Adam, R Civitarese, A Bugyei-Twum, KA Connelly |
The Canadian journal of cardiology | 2018 |
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The “adipose tissue expandability” hypothesis: a potential mechanism for insulin resistance in obese youth
S Caprio, B Pierpont, R Kursawe |
Hormone Molecular Biology and Clinical Investigation | 2018 |
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Cytosolic lipid excess-induced mitochondrial dysfunction is the cause or effect of high fat diet-induced skeletal muscle insulin resistance: a molecular insight
BA Jana, PK Chintamaneni, PT Krishnamurthy, A Wadhwani, SK Mohankumar |
Molecular Biology Reports | 2018 |
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The effect of high fat diet and metformin treatment on liver lipids accumulation and their impact on insulin action
P Zabielski, HR Hady, M Chacinska, K Roszczyc, J Gorski, AU Blachnio-Zabielska |
Scientific Reports | 2018 |
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Free fatty acid can induce cardiac dysfunction and alter insulin signaling pathways in the heart
L Han, J Liu, L Zhu, F Tan, Y Qin, H Huang, Y Yu |
Lipids in Health and Disease | 2018 |
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Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast
Z Liu, D Pouli, CA Alonzo, A Varone, S Karaliota, KP Quinn, K Münger, KP Karalis, I Georgakoudi |
Science Advances | 2018 |
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Ameliorative effects of taurine against diabetes: a review
I, F Piao, RM Aadil, R Suleman, K Li, M Zhang, P Wu, M Shahbaz, Z Ahmed |
Amino Acids | 2018 |
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Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice
S Paruthiyil, S Hagiwara, K Kundassery, A Bhargava |
Biology of sex differences | 2018 |
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Insulin Resistance, Prediabetes, Metabolic Syndrome: What Should Every Pediatrician Know?
A Ighbariya, R Weiss |
Journal of clinical research in pediatric endocrinology | 2018 |
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The Effect of Lean-Seafood and Non-Seafood Diets on Fasting and Postprandial Serum Metabolites and Lipid Species: Results from a Randomized Crossover Intervention Study in Healthy Adults
M Schmedes, C Balderas, E Aadland, H Jacques, C Lavigne, I Graff, Ø Eng, A Holthe, G Mellgren, J Young, U Sundekilde, B Liaset, H Bertram |
Nutrients | 2018 |
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Egg white hydrolysate and peptide reverse insulin resistance associated with tumor necrosis factor-α (TNF-α) stimulated mitogen-activated protein kinase (MAPK) pathway in skeletal muscle cells
M Son, J Wu |
European Journal of Nutrition | 2018 |
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Influence of Single-Nucleotide Polymorphisms in PPAR-δ, PPAR-γ, and PRKAA2 on the Changes in Anthropometric Indices and Blood Measurements through Exercise-Centered Lifestyle Intervention in Japanese Middle-Aged Men
Y Nishida, M Iyadomi, H Tominaga, H Taniguchi, Y Higaki, H Tanaka, M Horita, C Shimanoe, M Hara, K Tanaka |
International journal of molecular sciences | 2018 |
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Sex differences in body composition and association with cardiometabolic risk
M Schorr, LE Dichtel, AV Gerweck, RD Valera, M Torriani, KK Miller, MA Bredella |
Biology of sex differences | 2018 |
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Intrauterine hyperglycemia exposure results in intergenerational inheritance via DNA methylation reprogramming on F1 PGCs
J Ren, Y Cheng, ZH Ming, XY Dong, YZ Zhou, GL Ding, HY Pang, TU Rahman, R Akbar, HF Huang, JZ Sheng |
Epigenetics & chromatin | 2018 |
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Oral administration of short chain fatty acids could attenuate fat deposition of pigs
AR Jiao, H Diao, B Yu, J He, J Yu, P Zheng, ZQ Huang, YH Luo, JQ Luo, XB Mao, DW Chen, D Nie |
PloS one | 2018 |
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Impact of serum cholesterol esterification rates on the development of diabetes mellitus in a general population
S Tanaka, Y Fujioka, T Tsujino, T Ishida, K Hirata |
Lipids in Health and Disease | 2018 |
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Identification of key genes in non‑alcoholic fatty liver disease progression based on bioinformatics analysis
L Li, H Liu, X Hu, Y Huang, Y Wang, Y He, Q Lei |
Molecular medicine reports | 2018 |
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Type 2 diabetes – An autoinflammatory disease driven by metabolic stress
L Lopez, K Garrie, MD Turner |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2018 |
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Inhibition of adenosine deaminase and xanthine oxidase by valproic acid abates hepatic triglyceride accumulation independent of corticosteroids in female rats treated with estrogen–progestin
TE Omolekulo, ED Areola, OO Badmus, OS Michael, I Kim, LA Olatunji |
Canadian Journal of Physiology and Pharmacology | 2018 |
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Adipose Tissue
L Szablewski |
2018 | |
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Lifestyle genomics and the metabolic syndrome: A review of genetic variants that influence response to diet and exercise interventions
PH Fenwick, K Jeejeebhoy, R Dhaliwal, D Royall, P Brauer, A Tremblay, D Klein, DM Mutch |
Critical Reviews in Food Science and Nutrition | 2018 |
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Investigation of post-translational modifications in type 2 diabetes
B Chatterjee, SS Thakur |
Clinical Proteomics | 2018 |
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Royal jelly supplementation reduces skeletal muscle lipotoxicity and insulin resistance in aged obese rats
SE Ibrahim, AA Kosba |
Pathophysiology : the official journal of the International Society for Pathophysiology / ISP | 2018 |
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The effect of high-fat diet and inhibition of ceramide production on insulin action in liver: ZABIELSKI et al
P Zabielski, J Daniluk, HR Hady, AR Markowski, M Imierska, J Górski, AU Blachnio-Zabielska |
Journal of Cellular Physiology | 2018 |
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Assessment of anti-diabetic activity of peanut shell polyphenol extracts
X Sun, H Ye, J Liu, L Wu, D Lin, Y Yu, F Gao |
Journal of Zhejiang University SCIENCE B | 2018 |
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Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats
MD Inácio, A Rafacho, NA de Paula Camaforte, P Teixeira, PM Vareda, NM Violato, JR Bosqueiro |
International Journal of Endocrinology | 2018 |
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Inhibition of Ceramide De Novo Synthesis Affects Adipocytokine Secretion and Improves Systemic and Adipose Tissue Insulin Sensitivity
AU Blachnio-Zabielska, HR Hady, AR Markowski, A Kurianiuk, A Karwowska, J Górski, P Zabielski |
International journal of molecular sciences | 2018 |
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Molecular and Pathological Events Involved in the Pathogenesis of Diabetes-Associated Nonalcoholic Fatty Liver Disease
O Bedi, S Aggarwal, N Trehanpati, G Ramakrishna, P Krishan |
Journal of Clinical and Experimental Hepatology | 2018 |
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Effect of whole-grain plant-based diet on the diabetes mellitus type 2 features in newly diagnosed patients: a pilot study
K Saad-Aldin, M Altamimi |
International Journal of Diabetes in Developing Countries | 2018 |
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Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice
F Shigiyama, N Kumashiro, Y Tsuneoka, H Igarashi, F Yoshikawa, S Kakehi, H Funato, T Hirose |
American journal of physiology. Endocrinology and metabolism | 2018 |
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Prevalence of metabolic syndrome in veterans with spinal cord injury
DR Gater, GJ Farkas, AS Berg, C Castillo |
The journal of spinal cord medicine | 2018 |
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Exercise training impacts exercise tolerance and bioenergetics in gastrocnemius muscle of non-obese type-2 diabetic Goto-Kakizaki rat in vivo
M Macia, E Pecchi, M Desrois, C Lan, C Vilmen, B Portha, M Bernard, D Bendahan, B Giannesini |
Biochimie | 2018 |
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High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans
R de Cássia Lemos Lima, KT Kongstad, L Kato, MJ das Silva, H Franzyk, D Staerk |
Molecules (Basel, Switzerland) | 2018 |
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Dietary Inflammatory Index and Biomarkers of Lipoprotein Metabolism, Inflammation and Glucose Homeostasis in Adults
C Phillips, N Shivappa, J Hébert, I Perry |
Nutrients | 2018 |
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Metabolic perturbations in Welsh Ponies with insulin dysregulation, obesity, and laminitis
SI Jacob, KJ Murray, AK Rendahl, RJ Geor, NE Schultz, ME McCue |
Journal of Veterinary Internal Medicine | 2018 |
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Obesity in Type 1 Diabetes: Pathophysiology, Clinical Impact, and Mechanisms
KD Corbin, KA Driscoll, RE Pratley, SR Smith, DM Maahs, EJ Mayer-Davis |
Endocrine reviews | 2018 |
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Chitosan encapsulated nanocurcumin induces GLUT-4 translocation and exhibits enhanced anti-hyperglycemic function
P Chauhan, AK Tamrakar, S Mahajan, GB Prasad |
Life Sciences | 2018 |
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Generation of PDX-1 mutant porcine blastocysts by introducing CRISPR/Cas9-system into porcine zygotes via electroporation
F Tanihara, M Hirata, NT Nguyen, QA Le, T Hirano, T Takemoto, M Nakai, D Fuchimoto, T Otoi |
Animal Science Journal | 2018 |
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Electroacupuncture Mitigates Skeletal Muscular Lipid Metabolism Disorder Related to High-Fat-Diet Induced Insulin Resistance through the AMPK/ACC Signaling Pathway
Z Li, D Lan, H Zhang, H Zhang, X Chen, J Sun |
Evidence-Based Complementary and Alternative Medicine | 2018 |
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Neuropeptide receptors as potential pharmacological targets for obesity
BT Meneguetti, MH Cardoso, CF Ribeiro, MR Felício, IB Pinto, NC Santos, CM Carvalho, OL Franco |
Pharmacology & Therapeutics | 2018 |
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Effects of sodium salicylate on glucose kinetics and insulin signaling in postpartum dairy cows
SR Montgomery, LK Mamedova, M Zachut, G Kra, S Häussler, M Vaughn, J Gonzalez, BJ Bradford |
Journal of Dairy Science | 2018 |
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The protective effects of Δ 9 -tetrahydrocannabinol against inflammation and oxidative stress in rat liver with fructose-induced hyperinsulinemia
AB Beydogan, ZM Coskun, S Bolkent |
The Journal of pharmacy and pharmacology | 2018 |
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Risk assessment of urinary tract infections for patients receiving dapagliflozin
PC Chen, SH Hsu, YJ Chen, WH Ho, CP Hsu |
J INTELL FUZZY SYST | 2018 |
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Microbes: possible link between modern lifestyle transition and the rise of metabolic syndrome
S Moossavi, F Bishehsari |
Obesity reviews : an official journal of the International Association for the Study of Obesity | 2018 |
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Circadian clocks and insulin resistance
DJ Stenvers, FA Scheer, P Schrauwen, SE la Fleur, A Kalsbeek |
Nature Reviews Endocrinology | 2018 |
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ACSL4 gen polimorfizminin (rs7886473) metabolik sendrom ve lipid düzeyleri üzerine etkisi
E Vurgun, İY Diker, N Çoban, F Geyik, G Güven, NE Ünaltuna |
2018 | |
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The nutraceutical potential of Lepidium sativum L. seed flavonoid-rich extract in managing metabolic syndrome components: XXXX
I Lhadj, R Azzi, F Lahfa, EA Koceir, N Omari |
Journal of Food Biochemistry | 2018 |
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Prevalence of metabolic syndrome in veterans with spinal cord injury.
Gater DR Jr, Farkas GJ, Berg AS, Castillo C |
The journal of spinal cord medicine | 2018 |
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High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans.
de Cássia Lemos Lima R, T Kongstad K, Kato L, José das Silva M, Franzyk H, Staerk D |
Molecules (Basel, Switzerland) | 2018 |
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Dietary Inflammatory Index and Biomarkers of Lipoprotein Metabolism, Inflammation and Glucose Homeostasis in Adults.
Phillips CM, Shivappa N, Hébert JR, Perry IJ |
Nutrients | 2018 |
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Electroacupuncture Mitigates Skeletal Muscular Lipid Metabolism Disorder Related to High-Fat-Diet Induced Insulin Resistance through the AMPK/ACC Signaling Pathway.
Li Z, Lan D, Zhang H, Zhang H, Chen X, Sun J |
Evidence-based complementary and alternative medicine : eCAM | 2018 |
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Metabolic perturbations in Welsh Ponies with insulin dysregulation, obesity, and laminitis.
Jacob SI, Murray KJ, Rendahl AK, Geor RJ, Schultz NE, McCue ME |
Journal of Veterinary Internal Medicine | 2018 |
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Adipose tissue NAD + biology in obesity and insulin resistance: From mechanism to therapy
S Yamaguchi, J Yoshino |
BioEssays | 2017 |
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Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
KW Horst, PW Gilijamse, RI Versteeg, MT Ackermans, AJ Nederveen, SE la Fleur, JA Romijn, M Nieuwdorp, D Zhang, VT Samuel, DF Vatner, KF Petersen, GI Shulman, MJ Serlie |
Cell Reports | 2017 |
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Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases
VT Samuel, GI Shulman |
Cell Metabolism | 2017 |
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Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)
RJ Perry, L Peng, GW Cline, GM Butrico, Y Wang, XM Zhang, DL Rothman, KF Petersen, GI Shulman |
Nature Communications | 2017 |
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Mechanism by which arylamine N -acetyltransferase 1 ablation causes insulin resistance in mice
JP Camporez, Y Wang, K Faarkrog, N Chukijrungroat, KF Petersen, GI Shulman |
Proceedings of the National Academy of Sciences | 2017 |
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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
F Mauvais-Jarvis |
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity | 2017 |
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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
F Mauvais-Jarvis |
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity | 2017 |
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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
F Mauvais-Jarvis |
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity | 2017 |
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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
F Mauvais-Jarvis |
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity | 2017 |
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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
F Mauvais-Jarvis |
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity | 2017 |
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Macrovascular Complications in Patients with Diabetes and Prediabetes
D Huang, M Refaat, K Mohammedi, A Jayyousi, JA Suwaidi, CA Khalil |
BioMed Research International | 2017 |
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Obesity and Lipotoxicity
AB Engin, A Engin |
Obesity and Lipotoxicity | 2017 |
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Toll-like receptor-4 signaling mediates inflammation and tissue injury in diabetic nephropathy
G Garibotto, A Carta, D Picciotto, F Viazzi, D Verzola |
Journal of Nephrology | 2017 |
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Mulberry leaf alleviates streptozotocin-induced diabetic rats by attenuating NEFA signaling and modulating intestinal microflora
Y Sheng, S Zheng, T Ma, C Zhang, X Ou, X He, W Xu, K Huang |
Scientific Reports | 2017 |
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Lipid droplets and liver disease: from basic biology to clinical implications
NL Gluchowski, M Becuwe, TC Walther, RV Farese |
Nature Reviews Gastroenterology & Hepatology | 2017 |
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Neurogenic obesity and systemic inflammation following spinal cord injury: a review
GJ Farkas, DR Gater |
The journal of spinal cord medicine | 2017 |
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G Protein–Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus
DM Riddy, P Delerive, RJ Summers, PM Sexton, CJ Langmead, EL Barker |
Pharmacological reviews | 2017 |
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Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes
X Pan, N Zaarur, M Singh, P Morin, KV Kandror, PJ Brennwald |
Molecular biology of the cell | 2017 |
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Detection and Alterations of Acetylcarnitine in Human Skeletal Muscles by 1H MRS at 7 T:
R Klepochová, L Valkovič, M Gajdošík, T Hochwartner, H Tschan, M Krebs, S Trattnig, M Krššák |
Investigative Radiology | 2017 |
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Palmitate impairs angiogenesis via suppression of cathepsin activity
J Zhang, Y Shan, Y Li, X Luo, H Shi |
Molecular medicine reports | 2017 |
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Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation
Caprio S, Perry R, Kursawe R |
Gastroenterology | 2017 |
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Pioglitazone-induced improvements in insulin sensitivity occur without concomitant changes in muscle mitochondrial function
S Bajpeyi, M Pasarica, KE Conley, BR Newcomer, SA Jubrias, C Gamboa, K Murray, O Sereda, LM Sparks, SR Smith |
Metabolism | 2017 |
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Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice
B Noebauer, A Jais, J Todoric, K Gossens, H Sutterlüty-Fall, E Einwallner |
Journal of Diabetes Research | 2017 |
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Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus)
C Manickam, L Wachtman, AJ Martinot, LD Giavedoni, RK Reeves, G Alvisi |
PloS one | 2017 |
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Membrane Cholesterol in Skeletal Muscle: A Novel Player in Excitation-Contraction Coupling and Insulin Resistance
G Barrientos, P Sánchez-Aguilera, E Jaimovich, C Hidalgo, P Llanos |
Journal of Diabetes Research | 2017 |
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Non-alcoholic fatty liver disease (NAFLD) – pathogenesis, classification, and effect on drug metabolizing enzymes and transporters
E Cobbina, F Akhlaghi |
Drug Metabolism Reviews | 2017 |
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Skeletal muscle insulin resistance: role of mitochondria and other ROS sources
SD Meo, S Iossa, P Venditti |
Journal of Endocrinology | 2017 |
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Effect of lipid metabolism on male fertility
N Kim, H Nakamura, H Masaki, K Kumasawa, K Hirano, T Kimura |
Biochemical and Biophysical Research Communications | 2017 |
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Effects of intermittent fasting on glucose and lipid metabolism
R Antoni, KL Johnston, AL Collins, MD Robertson |
Proceedings of the Nutrition Society | 2017 |
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Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance
HC Kenny, F Rudwill, L Breen, M Salanova, D Blottner, T Heise, M Heer, S Blanc, DJ OGorman |
Diabetologia | 2017 |
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Manifold implications of obesity in ischemic heart disease among Japanese patients according to covariance structure analysis: Low reactivity of B-type natriuretic peptide as an intervening risk factor
J Tsutsumi, K Minai, M Kawai, K Ogawa, Y Inoue, S Morimoto, T Tanaka, T Nagoshi, T Ogawa, M Yoshimura, V Lionetti |
PloS one | 2017 |
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Hypothalamic Insulin Resistance in Obesity: Effects on Glucose Homeostasis
W Chen, E Balland, MA Cowley |
Neuroendocrinology | 2017 |
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DHHC7 Palmitoylates Glucose Transporter 4 (Glut4) and Regulates Glut4 Membrane Translocation
K Du, S Murakami, Y Sun, CL Kilpatrick, B Luscher |
The Journal of biological chemistry | 2017 |
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p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure
Y Liu, PL Leslie, A Jin, K Itahana, LM Graves, Y Zhang |
Scientific Reports | 2017 |
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Evidence of alterations in the expression of orphan receptors GPR26 and GPR39 due to the etiology of the metabolic syndrome
R Romero-Nava, DS Zhou, N García, A Ruiz-Hernández, YC Si, F Sánchez-Muñoz, F Huang, E Hong, S Villafaña |
Journal of Receptors and Signal Transduction | 2017 |
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Adipose tissue NAD + biology in obesity and insulin resistance: From mechanism to therapy
S Yamaguchi, J Yoshino |
BioEssays | 2017 |
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Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreatic β -Cells Function
C Carrasco-Pozo, KN Tan, M Gotteland, K Borges |
Oxidative medicine and cellular longevity | 2017 |
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Cigarette Smoking: An Accessory to the Development of Insulin Resistance
A Artese, BA Stamford, RJ Moffatt |
American journal of lifestyle medicine | 2017 |
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Adolescent Obesity and Insulin Resistance: Roles of Ectopic Fat Accumulation and Adipose Inflammation
S Caprio, R Perry, R Kursawe |
Gastroenterology | 2017 |
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Exercise and Health-Related Risks of Physical Deconditioning After Spinal Cord Injury
JL Maher, DW McMillan, MS Nash |
Topics in Spinal Cord Injury Rehabilitation | 2017 |
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Resistance training regulates gene expression of molecules associated with intramyocellular lipids, glucose signaling and fiber size in old rats
MB Ribeiro, V Guzzoni, JM Hord, GN Lopes, RC Marqueti, RV de Andrade, HS Selistre-de-Araujo, JL Durigan |
Scientific Reports | 2017 |
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Current views on neuropeptide Y and diabetes-related atherosclerosis
W Sun, P Zhu, Y Shi, C Zhang, X Huang, S Liang, Z Song, S Lin |
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease | 2017 |
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Gene Regulation, Epigenetics and Hormone Signaling
SS Mandal |
Gene Regulation, Epigenetics and Hormone Signaling | 2017 |
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Endothelial and Perivascular Adipose Tissue Abnormalities in Obesity-Related Vascular Dysfunction: Novel Targets for Treatment
F Schinzari, M Tesauro, C Cardillo |
Journal of Cardiovascular Pharmacology | 2017 |
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Maternal butyrate supplementation induces insulin resistance associated with enhanced intramuscular fat deposition in the offspring
Y Huang, S Gao, J Chen, E Albrecht, R Zhao, X Yang |
Oncotarget | 2017 |
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Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreatic β -Cells Function
C Carrasco-Pozo, KN Tan, M Gotteland, K Borges |
Oxidative medicine and cellular longevity | 2017 |
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Synthesis and biological evaluation of indole derivatives as α -amylase inhibitor
S Imran, M Taha, M Selvaraj, NH Ismail, S Chigurupati, JI Mohammad |
Bioorganic chemistry | 2017 |
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Tanshinone I alleviates insulin resistance in type 2 diabetes mellitus rats through IRS-1 pathway
Y Wei, J Gao, L Qin, Y Xu, D Wang, H Shi, T Xu, T Liu |
Biomedicine & Pharmacotherapy | 2017 |
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Pharmacological inhibition of diacylglycerol acyltransferase-1 and insights into postprandial gut peptide secretion
BS Maciejewski, TB Manion, CM Steppan |
World journal of gastrointestinal pathophysiology | 2017 |
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Jia-Wei-Jiao-Tai-Wan ameliorates type 2 diabetes by improving β cell function and reducing insulin resistance in diabetic rats
G Chen, X Yang, X Yang, L Li, J Luo, H Dong, L Xu, P Yi, K Wang, X Zou, F Lu |
BMC complementary and alternative medicine | 2017 |
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Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action
EA Oshaghi, MT Goodarzi, V Higgins, K Adeli |
Critical Reviews in Clinical Laboratory Sciences | 2017 |
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Investigation of antihyperglycaemic activity of banana (Musa sp. Var. Nanjangud rasa bale) flower in normal and diabetic rats
R Ramu, PS Shirahatti, SP Dhanabal, F Zameer, BL Dhananjaya, MN Prasad |
Pharmacognosy magazine | 2017 |
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Effects of synbiotic food consumption on serum minerals, liver enzymes, and blood pressure in patients with type 2 diabetes: A double-blind randomized cross-over controlled clinical trial
Z Asemi, MH Aarabi, M Hajijafari, SA Alizadeh, R Razzaghi, M Mazoochi, A Esmaillzadeh |
International journal of preventive medicine | 2017 |
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Obesity and Brain Function
L Letra, R Seiça |
Obesity and Brain Function | 2017 |
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Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice
J Guo, H Tao, A Alasadi, Q Huang, S Jin |
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity | 2017 |
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Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction
X Hua, XY Cao, XL Wang, P Sun, L Chen |
Toxicological Sciences | 2017 |
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Improvement of obesity-linked skeletal muscle insulin resistance by strength and endurance training
SD Meo, S Iossa, P Venditti |
Journal of Endocrinology | 2017 |
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Optimal cutoff for the evaluation of insulin resistance through triglyceride-glucose index: A cross-sectional study in a Venezuelan population
J Salazar, V Bermúdez, M Calvo, L Olivar, E Luzardo, C Navarro, H Mencia, M Martínez, J Rivas-Ríos, S Wilches-Durán, M Cerda, M Graterol, R Graterol, C Garicano, J Hernández, J Rojas |
F1000Research | 2017 |
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Microcystin-LR disrupts insulin signaling by hyperphosphorylating insulin receptor substrate 1 and glycogen synthase
J Liu, C Xu, S Zhang, H Li, K Chen, P Huang, Z Guo, L Xu |
Environmental Toxicology | 2017 |
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Ectopic fat accumulation in the pancreas and its biomarkers: A systematic review and meta-analysis
RG Singh, HD Yoon, SD Poppitt, LD Plank, MS Petrov |
Diabetes/Metabolism Research and Reviews | 2017 |
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Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3
AS Wagman, RS Boyce, SP Brown, E Fang, D Goff, JM Jansen, VP Le, BH Levine, SC Ng, ZJ Ni, JM Nuss, KB Pfister, S Ramurthy, PA Renhowe, DB Ring, W Shu, S Subramanian, XA Zhou, CM Shafer, SD Harrison, KW Johnson, DE Bussiere |
Journal of Medicinal Chemistry | 2017 |
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Obesity as a Disease
J Upadhyay, O Farr, N Perakakis, W Ghaly, C Mantzoros |
Medical Clinics of North America | 2017 |
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Impaired Vascular Redox Signalling in the Vascular Complications of Obesity and Diabetes Mellitus
I Akoumianakis, C Antoniades |
Antioxidants & Redox Signaling | 2017 |
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Type 2 diabetes: Does pancreatic fat really matter?
V Guglielmi, P Sbraccia |
Diabetes/Metabolism Research and Reviews | 2017 |
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Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly
MA Bredella, M Schorr, LE Dichtel, AV Gerweck, BJ Young, WW Woodmansee, B Swearingen, KK Miller |
The Journal of clinical endocrinology and metabolism | 2017 |
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Palmitate induces neuroinflammation, ER stress, and Pomc mRNA expression in hypothalamic mHypoA-POMC/GFP neurons through novel mechanisms that are prevented by oleate
EK Tse, DD Belsham |
Molecular and Cellular Endocrinology | 2017 |
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Serum adiponectin and TNFα concentrations are closely associated with epicardial adipose tissue fatty acid profiles in patients undergoing cardiovascular surgery
T Sawaguchi, T Nakajima, T Hasegawa, I Shibasaki, H Kaneda, S Obi, T Kuwata, M Sakuma, S Toyoda, M Ohni, S Abe, H Fukuda, T Inoue |
IJC Heart & Vasculature | 2017 |
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Treating nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus: a review of efficacy and safety
EP Mills, KP Brown, JD Smith, PW Vang, K Trotta |
Therapeutic Advances in Endocrinology and Metabolism | 2017 |
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Mechanism by which arylamine N -acetyltransferase 1 ablation causes insulin resistance in mice
JP Camporez, Y Wang, K Faarkrog, N Chukijrungroat, KF Petersen, GI Shulman |
Proceedings of the National Academy of Sciences | 2017 |
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The effects of hypoglycemia and weight loss of total lignans from Fructus Arctii in KKAy mice and its mechanisms of the activity
Y Gao, C Gu, K Wang, H Wang, K Ruan, Z Xu, Y Feng |
Phytotherapy Research | 2017 |
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Management of diabetes using herbal extracts: review
WH El-Tantawy, A Temraz |
Archives Of Physiology And Biochemistry | 2017 |
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Pediatric Obesity
MS Freemark |
Pediatric Obesity | 2017 |
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Hispidin rescues palmitate-induced insulin resistance in C2C12 myotubes
JS Lee, JM Park, S Lee, HJ Lee, HS Yang, J Yeo, KR Lee, BH Choi, EK Hong |
Molecular medicine reports | 2017 |
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Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases
ZJ Yi, JP Gong, W Zhang |
Molecular medicine reports | 2017 |
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Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish
BY Yang, G Zhai, YL Gong, JZ Su, XY Peng, GH Shang, D Han, JY Jin, HK Liu, ZY Du, Z Yin, SQ Xie |
American journal of physiology. Endocrinology and metabolism | 2017 |
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Evolution of Human Sex-Specific Cognitive Vulnerabilities
DC Geary |
The Quarterly Review of Biology | 2017 |
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Histone deacetylase inhibition of cardiac autophagy in rats on a high‑fat diet with low‑dose streptozotocin-induced type 2 diabetes mellitus
TI Lee, KJ Bai, YC Chen, TW Lee, CC Chung, WC Tsai, SY Tsao, YH Kao |
Molecular medicine reports | 2017 |
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Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice.
Guo J, Tao H, Alasadi A, Huang Q, Jin S |
Eating and weight disorders : EWD | 2017 |
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EFFECT OF PROBIOTIC FERMENTED MILK (KEFIR) ON SERUM LEVEL OF INSULIN AND HOMOCYSTEINE IN TYPE 2 DIABETES PATIENTS.
Alihosseini N, Moahboob SA, Farrin N, Mobasseri M, Taghizadeh A, Ostadrahimi AR |
2017 | |
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Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly.
Bredella MA, Schorr M, Dichtel LE, Gerweck AV, Young BJ, Woodmansee WW, Swearingen B, Miller KK |
The Journal of clinical endocrinology and metabolism | 2017 |
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Treating nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus: a review of efficacy and safety.
Mills EP, Brown KPD, Smith JD, Vang PW, Trotta K |
Therapeutic Advances in Endocrinology and Metabolism | 2017 |
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Serum adiponectin and TNFα concentrations are closely associated with epicardial adipose tissue fatty acid profiles in patients undergoing cardiovascular surgery.
Sawaguchi T, Nakajima T, Hasegawa T, Shibasaki I, Kaneda H, Obi S, Kuwata T, Sakuma M, Toyoda S, Ohni M, Abe S, Fukuda H, Inoue T |
2017 | |
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The Use of Silk as a Scaffold for Mature, Sustainable Unilocular Adipose 3D Tissue Engineered Systems
RD Abbott, RY Wang, MR Reagan, Y Chen, FE Borowsky, A Zieba, KG Marra, JP Rubin, IM Ghobrial, DL Kaplan |
Advanced Healthcare Materials | 2016 |
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Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis
RJ Perry, KF Petersen, GI Shulman |
Diabetologia | 2016 |
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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M de Bunt, KJ Gaulton, JD Eicher, SJ Sharp, J Luan, ED Rolfe, ID Stewart, E Wheeler, SM Willems, C Adams, H Yaghootkar, C Langenberg, RA Scott, SJ Sharp, NG Forouhi, ND Kerrison, M Sims, DM Lucarelli, I Barroso, P Deloukas, MI McCarthy, L Arriola, B Balkau, A Barricarte, H Boeing, PW Franks, C Gonzalez, S Grioni, R Kaaks, TJ Key, C Navarro, PM Nilsson, K Overvad, D Palli, S Panico, JR Quirós, O Rolandsson, C Sacerdote, E Salamanca-Fernández, N Slimani, A Tjonneland, R Tumino, AM Spijkerman, DL van der A, YT van der Schouw, E Riboli, NJ Wareham, RK Semple, C Adams, A Stears, S George, M Walker, E Gurnell, D Maguire, R Mukhtar, S Nag, A Adler, M Soeters, K Laji, A Watt, S Aylwin, A Johnson, G Rayman, F Hanna, S Ellard, R Ross, K Blaslov, LS Duvnjak, S O'Rahilly, DB Savage, NG Forouhi, KT Khaw, AD Johnson, RK Semple, T Frayling, JR Perry, E Dermitzakis, MI McCarthy, I Barroso, NJ Wareham, DB Savage, C Langenberg, S O'Rahilly, RA Scott |
Nature Genetics | 2016 |
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Mitochondrial fat oxidation is essential for lipid-induced inflammation in skeletal muscle in mice
JD Warfel, EM Bermudez, TM Mendoza, S Ghosh, J Zhang, CM Elks, R Mynatt, B Vandanmagsar |
Scientific Reports | 2016 |
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Ursolic acid and rosiglitazone combination improves insulin sensitivity by increasing the skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat diet-fed C57BL/6J mice
A Sundaresan, T Radhiga, KV Pugalendi |
Journal of Physiology and Biochemistry | 2016 |
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Efficacy and risk profile of anti-diabetic therapies: Conventional vs traditional drugs—A mechanistic revisit to understand their mode of action
P Gupta, M Bala, S Gupta, A Dua, R Dabur, E Injeti, A Mittal |
Pharmacological Research | 2016 |
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Combatting type 2 diabetes by turning up the heat
P Schrauwen, WD van Lichtenbelt |
Diabetologia | 2016 |
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Mitochondrial involvement in skeletal muscle insulin resistance: A case of imbalanced bioenergetics
C Affourtit |
Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2016 |
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Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?
K Rehman, MS Akash |
Journal of Biomedical Science | 2016 |
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Harveian Oration 2016: Some observations on the causes and consequences of obesity
S O'Rahilly |
Clinical Medicine | 2016 |
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Chrysobalanus icaco L. Leaves Normalizes Insulin Sensitivity and Blood Glucose and Inhibits Weight Gain in High-Fat Diet-Induced Obese Mice
PA White, JM Araújo, LM Cercato, LA Souza, AP Barbosa, LJ Quintans-Junior, UF Machado, EA Camargo, LC Brito, MR Santos |
Journal of Medicinal Food | 2016 |
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Leucine in Obesity: Therapeutic Prospects
K Yao, Y Duan, F Li, B Tan, Y Hou, G Wu, Y Yin |
Trends in Pharmacological Sciences | 2016 |
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Antisense-Mediated Lowering of Plasma Apolipoprotein C-III by Volanesorsen Improves Dyslipidemia and Insulin Sensitivity in Type 2 Diabetes
A Digenio, RL Dunbar, VJ Alexander, M Hompesch, L Morrow, RG Lee, MJ Graham, SG Hughes, R Yu, W Singleton, BF Baker, S Bhanot, RM Crooke |
Diabetes care | 2016 |
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Excess of Free Fatty Acids as a Cause of Metabolic Dysfunction in Skeletal Muscle
J Tumova, M Andel, J Trnka |
Physiological research / Academia Scientiarum Bohemoslovaca | 2016 |
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Association between insulin resistance and impairment of FGF21 signal transduction in skeletal muscles
JY Jeon, SE Choi, ES Ha, TH Kim, JG Jung, SJ Han, HJ Kim, DJ Kim, Y Kang, KW Lee |
Endocrine | 2016 |
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What is the appropriate upper limit for added sugars consumption?
JM Rippe, JL Sievenpiper, KA Lê, JS White, R Clemens, TJ Angelopoulos |
Nutrition Reviews | 2016 |
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Epicardial Fat: Physiological, Pathological, and Therapeutic Implications
J Salazar, E Luzardo, JC Mejías, J Rojas, A Ferreira, JR Rivas-Ríos, V Bermúdez |
Cardiology Research and Practice | 2016 |
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The role of epsilon PKC in acute and chronic diseases: Possible pharmacological implications of its modulators
B Capuani, F Pacifici, D Pastore, R Palmirotta, G Donadel, R Arriga, A Bellia, ND Daniele, P Rogliani, P Abete, P Sbraccia, F Guadagni, D Lauro, D Della-Morte |
Pharmacological Research | 2016 |
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Type 2 Diabetes in the Elderly: Challenges in a Unique Patient Population
Bradley D, Hsueh W |
2016 | |
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Orchestrating Lymphocyte Polarity in Cognate Immune Cell-Cell Interactions.
Bustos-Morán E, Blas-Rus N, Martín-Cófreces NB, Sánchez-Madrid F |
International review of cell and molecular biology | 2016 |
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Endocrinology: Adult and Pediatric
M Gurnell, TJ Visser, P Beck-Peccoz, VK Chatterjee |
Endocrinology: Adult and Pediatric | 2016 |
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Interactions between kidney disease and diabetes: dangerous liaisons
R Pecoits-Filho, H Abensur, CC Betônico, AD Machado, EB Parente, M Queiroz, JE Salles, S Titan, S Vencio |
Diabetology & metabolic syndrome | 2016 |
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High Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo Approach
EN Katsoulieris, GI Drossopoulou, ES Kotsopoulou, DV Vlahakos, EA Lianos, EC Tsilibary, V Sánchez-Margalet |
PloS one | 2016 |
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Human Fetal Growth and Development
BC Melnik |
Human Fetal Growth and Development | 2016 |
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Molecular Nutrition and Diabetes
D Sala, A Zorzano |
Molecular Nutrition and Diabetes | 2016 |
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The effects of short-chain fatty acids on the cardiovascular system
LB Richards, M Li, BC Esch, J Garssen, G Folkerts |
PharmaNutrition | 2016 |
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Molecular Basis of Nutrition and Aging
E Suh, SW Choi, S Friso |
Molecular Basis of Nutrition and Aging | 2016 |
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Differential Acute Impacts of Sleeve Gastrectomy, Roux-en-Y Gastric Bypass Surgery and Matched Caloric Restriction Diet on Insulin Secretion, Insulin Effectiveness and Non-Esterified Fatty Acid Levels Among Patients with Type 2 Diabetes
F Thomas, GC Smith, J Lu, R Babor, M Booth, G Beban, JG Chase, R Murphy |
Obesity Surgery | 2016 |
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Reactive oxygen species: sources, consequences and targeted therapy in type 2 diabetes
SK Panigrahy, R Bhatt, A Kumar |
Journal of Drug Targeting | 2016 |
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Extract of Sesbania grandiflora Ameliorates Hyperglycemia in High Fat Diet-Streptozotocin Induced Experimental Diabetes Mellitus
G Panigrahi, C Panda, A Patra |
Scientifica | 2016 |
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The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice
MG Schooneman, RH Houtkooper, CE Hollak, RJ Wanders, FM Vaz, MR Soeters, SM Houten |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2016 |
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Prevention of Obesity and Type 2 Diabetes with Aged Citrus Peel ( Chenpi ) Extract
J Guo, H Tao, Y Cao, CT Ho, S Jin, Q Huang |
Journal of Agricultural and Food Chemistry | 2016 |
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Human Skeletal Muscle Disuse Atrophy: Effects on Muscle Protein Synthesis, Breakdown, and Insulin Resistance—A Qualitative Review
SS Rudrappa, DJ Wilkinson, PL Greenhaff, K Smith, I Idris, PJ Atherton |
Frontiers in physiology | 2016 |
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Design and synthesis of pyridazinone-substituted benzenesulphonylurea derivatives as anti-hyperglycaemic agents and inhibitors of aldose reductase – an enzyme embroiled in diabetic complications
R Yaseen, H Pushpalatha, GB Reddy, A Ismael, A Ahmed, A Dheyaa, S Ovais, P Rathore, M Samim, M Akthar, K Sharma, S Shafi, S Singh, K Javed |
Journal of Enzyme Inhibition and Medicinal Chemistry | 2016 |
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Assessment of plasma acylcarnitines before and after weight loss in obese subjects
MG Schooneman, A Napolitano, SM Houten, GK Ambler, PR Murgatroyd, SR Miller, CE Hollak, CY Tan, S Virtue, A Vidal-Puig, DJ Nunez, MR Soeters |
Archives of Biochemistry and Biophysics | 2016 |
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Normocaloric Diet Restores Weight Gain and Insulin Sensitivity in Obese Mice
GE Lombardo, B Arcidiacono, RF de Rose, SM Lepore, N Costa, T Montalcini, A Brunetti, D Russo, GD Sarro, M Celano |
Frontiers in Endocrinology | 2016 |
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Association between the Hypertriglyceridemic Waist Phenotype, Prediabetes, and Diabetes Mellitus in Rural Chinese Population: A Cross-Sectional Study
S Chen, X Guo, S Yu, G Sun, Z Li, Y Sun |
International journal of environmental research and public health | 2016 |
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Zinc supplementation ameliorates glycoprotein components and oxidative stress changes in the lung of streptozotocin diabetic rats
O Sacan, IB Turkyilmaz, BB Bayrak, O Mutlu, N Akev, R Yanardag |
BioMetals | 2016 |
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Effects of Tocotrienols on Insulin Secretion-Associated Genes Expression of Rat Pancreatic Islets in a Dynamic Culture
LL Chia, I Jantan, KH Chua, KW Lam, K Rullah, MF Aluwi |
Frontiers in pharmacology | 2016 |
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Acute Ozone-Induced Pulmonary and Systemic Metabolic Effects Are Diminished in Adrenalectomized Rats
DB Miller, SJ Snow, MC Schladweiler, JE Richards, AJ Ghio, AD Ledbetter, UP Kodavanti |
Toxicological Sciences | 2016 |
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Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice
M Huang, S Deng, Q Han, P Zhao, Q Zhou, S Zheng, X Ma, C Xu, J Yang, X Yang |
Frontiers in pharmacology | 2016 |
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Gut microbiota can transfer fiber characteristics and lipid metabolic profiles of skeletal muscle from pigs to germ-free mice
H Yan, H Diao, Y Xiao, W Li, B Yu, J He, J Yu, P Zheng, X Mao, Y Luo, B Zeng, H Wei, D Chen |
Scientific Reports | 2016 |
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Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance
B Bigio, AA Mathé, VC Sousa, D Zelli, P Svenningsson, BS McEwen, C Nasca |
Proceedings of the National Academy of Sciences | 2016 |
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The anti-diabetic activity of oat β-d-glucan in streptozotocin–nicotinamide induced diabetic mice
M Liu, Y Zhang, H Zhang, B Hu, L Wang, H Qian, X Qi |
International Journal of Biological Macromolecules | 2016 |
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Elmo2 Is a Regulator of Insulin-dependent Glut4 Membrane Translocation
Y Sun, JF Côté, K Du |
The Journal of biological chemistry | 2016 |
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Spirulina vesicolor Improves Insulin Sensitivity and Attenuates Hyperglycemia-Mediated Oxidative Stress in Fructose-Fed Rats
W Hozayen, A Mahmoud, H Soliman, S Mostafa |
Journal of Intercultural Ethnopharmacology | 2016 |
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Adipose Insulin Resistance in Obese Adolescents Across the Spectrum of Glucose Tolerance
K Hershkop, O Besor, N Santoro, B Pierpont, S Caprio, R Weiss |
The Journal of clinical endocrinology and metabolism | 2016 |
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Effect of Health Exercise Program on Insulin Resistant and Blood Lipid of Elderly Women Through Convergence
SY Kim |
Journal of Digital Convergence | 2016 |
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Effect of bergenin on hepatic glucose metabolism and insulin signaling in C57BL/6J mice with high fat-diet induced type 2 diabetes
S Ambika, R Saravanan |
Journal of Applied Biomedicine | 2016 |
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Effect of Ethanolic Extract of Moringa oleifera Lam. Leaves on Body Weight and Hyperglycemia of Diabetic Rats
HM Irfan, MZ Asmawi, NA Khan, A Sadikun |
Pakistan Journal of Nutrition | 2016 |
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Calorie Restricted High Protein Diets Downregulate Lipogenesis and Lower Intrahepatic Triglyceride Concentrations in Male Rats
L Margolis, D Rivas, Y Ezzyat, E Gaffney-Stomberg, A Young, J McClung, R Fielding, S Pasiakos |
Nutrients | 2016 |
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Metformin Improves Metabolic Memory in High Fat Diet (HFD)-induced Renal Dysfunction
K Tikoo, E Sharma, VR Amara, H Pamulapati, VS Dhawale |
The Journal of biological chemistry | 2016 |
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The Interplay of Autoimmunity and Insulin Resistance in Type 1 Diabetes
Natalie J. Nokoff, Marian Rewers, Melanie Cree Green |
Discovery medicine | 2016 |
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Endocrinology
C Napier, SH Pearce |
Endocrinology | 2016 |
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Beneficial effects of sodium-glucose cotransporter 2 inhibitors for preservation of pancreatic β -cell function and reduction of insulin resistance: 钠-葡萄糖共转运体2抑制剂对保护胰腺β细胞功能以及降低胰岛素抵抗的有益影响
H Kaneto, A Obata, T Kimura, M Shimoda, S Okauchi, N Shimo, T Matsuoka, K Kaku |
Journal of Diabetes | 2016 |
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MECHANISMS IN ENDOCRINOLOGY: Skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes: a causal mechanism or an innocent bystander?
C Brøns, LG Grunnet |
European Journal of Endocrinology | 2016 |
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Abdominal Adiposity, Not Cardiorespiratory Fitness, Mediates the Exercise-Induced Change in Insulin Sensitivity in Older Adults
G Ko, LE Davidson, AM Brennan, M Lam, R Ross, A Philp |
PloS one | 2016 |
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High Dietary Fructose Intake on Cardiovascular Disease Related Parameters in Growing Rats
SY Yoo, H Ahn, Y Park |
Nutrients | 2016 |
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Obesity and Cancer Mechanisms: Cancer Metabolism
BD Hopkins, MD Goncalves, LC Cantley |
Journal of Clinical Oncology | 2016 |
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The Effect of Ephedra sinica Pharmacopuncture on Lipid Metabolism in an Experimental Mouse Model of Obesity
H Kim, E Kim, Y Han |
The Journal of Internal Korean Medicine | 2016 |
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The Physiology of Exercise in Spinal Cord Injury
JA Taylor |
The Physiology of Exercise in Spinal Cord Injury | 2016 |
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Effect of Pilates Exercises on Adiponectin, %Body fat and HOMA Index in Obese Women
이정윤, L Seo-Hyung |
Official Journal of the Koeran Society of Dance Science | 2016 |
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Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases
K Zarkovic, A Jakovcevic, N Zarkovic |
Free radical biology & medicine | 2016 |
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Origanum Majoranum Extract Modulates Gene Expression, Hepatic and Renal Changes in a Rat Model of Type 2 Diabetes
Mohamed Mohamed Soliman, Mohamed Abdo Nassan, Tamer Ahmed Ismail |
IRAN J PHARM RES | 2016 |
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LA and ALA prevent glucose intolerance in obese male rats without reducing reactive lipid content, but cause tissue-specific changes in fatty acid composition
S Matravadia, P Zabielski, A Chabowski, DM Mutch, GP Holloway |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2016 |
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Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance
E Vavrova, V Lenoir, MC Alves-Guerra, RG Denis, J Castel, C Esnous, JR Dyck, S Luquet, D Metzger, F Bouillaud, C Prip-Buus |
American journal of physiology. Endocrinology and metabolism | 2016 |
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Musculoskeletal Disease Associated with Diabetes Mellitus
M Inaba |
2016 | |
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Sugar: The Bitter Truth
J Glynn |
2016 | |
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Papel de las lipasas metabólicas y la lipotoxicidad en el desarrollo de esteatosis hepática y esteatohepatitis no alcohólica
A Berlanga, E Guiu-Jurado, JA Porras, G Aragonès, T Auguet |
Clínica e Investigación en Arteriosclerosis | 2015 |
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Deepure Tea Improves High Fat Diet-Induced Insulin Resistance and Nonalcoholic Fatty Liver Disease
JN Deng, J Li, HN Mu, YY Liu, MX Wang, CS Pan, JY Fan, F Ye, JY Han |
Evidence-Based Complementary and Alternative Medicine | 2015 |
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Pediatric obesity. An introduction
JA Yanovski |
Appetite | 2015 |
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Insulin resistance: an additional risk factor in the pathogenesis of cardiovascular disease in type 2 diabetes
TP Patel, K Rawal, AK Bagchi, G Akolkar, N Bernardes, DS Dias, S Gupta, PK Singal |
Heart Failure Reviews | 2015 |
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Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus
S Tangvarasittichai |
World journal of diabetes | 2015 |
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Type-2 diabetes: Current understanding and future perspectives: Type-2 Diabetes
A Pandey, S Chawla, P Guchhait |
IUBMB Life | 2015 |
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Human cancer: Is it linked to dysfunctional lipid metabolism?
S Hashmi, Y Wang, DS Suman, RS Parhar, K Collison, W Conca, F Al-Mohanna, R Gaugler |
Biochimica et Biophysica Acta (BBA) - General Subjects | 2015 |
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The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development – a potential therapeutic target?
P Dongiovanni, R Rametta, M Meroni, L Valenti |
Expert Review of Gastroenterology & Hepatology | 2015 |
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Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation
CL Kien, DE Matthews, ME Poynter, JY Bunn, NK Fukagawa, KI Crain, DB Ebenstein, EK Tarleton, RD Stevens, TR Koves, DM Muoio |
Journal of lipid research | 2015 |
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The Use of SGLT-2 Inhibitors in Type 2 Diabetes and Heart Failure
K Riggs, H Ali, H Taegtmeyer, AD Gutierrez |
Metabolic Syndrome and Related Disorders | 2015 |
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Metabolome and proteome changes with aging in Caenorhabditis elegans
N Copes, C Edwards, D Chaput, M Saifee, I Barjuca, D Nelson, A Paraggio, P Saad, D Lipps, SM Stevens, PC Bradshaw |
Experimental Gerontology | 2015 |
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Stress kinases in the modulation of metabolism and energy balance
E Manieri, G Sabio |
Journal of Molecular Endocrinology | 2015 |
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Evidence for the Effects of Yogurt on Gut Health and Obesity
R Pei, DA Martin, DM DiMarco, BW Bolling |
Critical Reviews in Food Science and Nutrition | 2015 |
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Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes
AP Arruda, GS Hotamisligil |
Cell Metabolism | 2015 |
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Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease
A Iyer, L Brown, JP Whitehead, JB Prins, DP Fairlie |
The FASEB Journal | 2015 |
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Long-term fatty liver-induced insulin resistance in orotic acid-induced nonalcoholic fatty liver rats
X Han, C Liu, Y Xue, J Wang, C Xue, T Yanagita, X Gao, Y Wang |
Bioscience Biotechnology and Biochemistry | 2015 |
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Free fatty acid induced impairment of insulin signaling is prevented by the diastereomeric mixture of calophyllic acid and isocalophyllic acid in skeletal muscle cells
N Jaiswal, N Gunaganti, CK Maurya, T Narender, AK Tamrakar |
European Journal of Pharmacology | 2015 |
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Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity
GS Ma, I Lopez-Sanchez, N Aznar, N Kalogriopoulos, S Pedram, K Midde, TP Ciaraldi, RR Henry, P Ghosh |
Molecular biology of the cell | 2015 |
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A Difference in Fatty Acid Composition of Isocaloric High-Fat Diets Alters Metabolic Flexibility in Male C57BL/6JOlaHsd Mice
LP Duivenvoorde, EM van Schothorst, HM Swarts, O Kuda, E Steenbergh, S Termeulen, J Kopecky, J Keijer, M Alemany |
PloS one | 2015 |
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Elevated whole blood viscosity is associated with insulin resistance and non-alcoholic fatty liver
H Zhao, J Li, M Xu, T Wang, W Sun, Y Chen, Y Bi, W Wang, G Ning |
Clinical Endocrinology | 2015 |
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Involvement of mTOR in Type 2 CRF Receptor Inhibition of Insulin Signaling in Muscle Cells
H Chao, H Li, R Grande, V Lira, Z Yan, TE Harris, C Li |
Molecular Endocrinology | 2015 |
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RNASET2 is required for ROS propagation during oxidative stress-mediated cell death
G Caputa, S Zhao, AE Criado, DS Ory, JG Duncan, JE Schaffer |
Cell Death and Differentiation | 2015 |
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Second-generation antisense oligonucleotides against -catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance
VB Popov, FR Jornayvaz, EO Akgul, S Kanda, MJ Jurczak, D Zhang, A Abudukadier, SK Majumdar, B Guigni, KF Petersen, VP Manchem, S Bhanot, GI Shulman, VT Samuel |
The FASEB Journal | 2015 |
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Mitochondrial efficiency and insulin resistance
R Crescenzo, F Bianco, A Mazzoli, A Giacco, G Liverini, S Iossa |
Frontiers in physiology | 2015 |
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Health Implications of High-Fructose Intake and Current Research
WC Dornas, WG de Lima, ML Pedrosa, ME Silva |
Advances in nutrition (Bethesda, Md.) | 2015 |
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3,4-dihydroxyphenylacetic acid, a microbiota-derived metabolite Of quercetin, protects against pancreatic β-cells dysfunction induced by high cholesterol
C Carrasco-pozo, M Gotteland, R Castillo, C Chen |
Experimental Cell Research | 2015 |
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Adiponectin: Probe of the molecular paradigm associating diabetes and obesity
K Ghoshal |
World journal of diabetes | 2015 |
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FTIR imaging of structural changes in visceral and subcutaneous adiposity and brown to white adipocyte transdifferentiation
FK Baloglu, S Garip, S Heise, G Brockmann, F Severcan |
The Analyst | 2015 |
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Lifestyle and the Prevention of Type 2 Diabetes: A Status Report
Galaviz KI, Narayan KM, Lobelo F, Weber MB |
American journal of lifestyle medicine | 2015 |
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Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice
EK Lees, E Krol, K Shearer, N Mody, TW Gettys, M Delibegovic |
Metabolism | 2015 |
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Muscle-selective knockout of AMPKα2 does not exacerbate diet-induced obesity probably related to altered myokines expression
T Chen, Z Li, Y Zhang, F Feng, X Wang, X Wang, QW Shen |
Biochemical and Biophysical Research Communications | 2015 |
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Integrative Proteomics and Targeted Transcriptomics Analyses in Cardiac Endothelial Cells Unravel Mechanisms of Long-Term Radiation-Induced Vascular Dysfunction
O Azimzadeh, W Sievert, H Sarioglu, J Merl-Pham, R Yentrapalli, MV Bakshi, D Janik, M Ueffing, MJ Atkinson, G Multhoff, S Tapio |
Journal of Proteome Research | 2015 |
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In Vivo Performance and Biocompatibility of a Subcutaneous Implant for Real-Time Glucose-Responsive Insulin Delivery
MK Chu, CR Gordijo, J Li, AZ Abbasi, A Giacca, O Plettenburg, XY Wu |
Diabetes Technology & Therapeutics | 2015 |
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Caulerpa lentillifera extract ameliorates insulin resistance and regulates glucose metabolism in C57BL/KsJ-db/db mice via PI3K/AKT signaling pathway in myocytes
BR Sharma, HJ Kim, DY Rhyu |
Journal of Translational Medicine | 2015 |
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Angelica sinensis polysaccharide regulates glucose and lipid metabolism disorder in prediabetic and streptozotocin-induced diabetic mice through the elevation of glycogen levels and reduction of inflammatory factors
K Wang, P Cao, W Shui, Q Yang, Z Tang, Y Zhang |
Food & Function | 2015 |
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Altered Fetal Skeletal Muscle Nutrient Metabolism Following an Adverse In Utero Environment and the Modulation of Later Life Insulin Sensitivity
K Dunlop, M Cedrone, J Staples, T Regnault |
Nutrients | 2015 |
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GSK256073 acutely regulates NEFA levels via HCA2 agonism but does not achieve durable glycaemic control in type 2 diabetes. A randomised trial
R Dobbins, R Byerly, R Gaddy, F Gao, K Mahar, A Napolitano, P Ambery, AC de Gouville |
European Journal of Pharmacology | 2015 |
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Greater Skeletal Muscle Fat Infiltration Is Associated With Higher All-Cause and Cardiovascular Mortality in Older Men
I Miljkovic, AL Kuipers, JA Cauley, T Prasad, CG Lee, KE Ensrud, PM Cawthon, AR Hoffman, TT Dam, CL Gordon, JM Zmuda |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2015 |
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Glut4 palmitoylation at Cys223 plays a critical role in Glut4 membrane trafficking
W Ren, Y Sun, K Du |
Biochemical and Biophysical Research Communications | 2015 |
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Bariatric Surgery in Morbidly Obese Insulin Resistant Humans Normalises Insulin Signalling but Not Insulin-Stimulated Glucose Disposal
MZ Chen, CA Hudson, EE Vincent, DA de Berker, MT May, I Hers, CM Dayan, RC Andrews, JM Tavaré, A Wolfe |
PloS one | 2015 |
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Genetic ablation of PRAS40 improves glucose homeostasis via linking the AKT and mTOR pathways
R Malla, Y Wang, WK Chan, AK Tiwari, JS Faridi |
Biochemical Pharmacology | 2015 |
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Insulin response of the glucose and fatty acid metabolism in dry dairy cows across a range of body condition scores
JD Koster, M Hostens, MV Eetvelde, K Hermans, S Moerman, H Bogaert, E Depreester, WV Broeck, G Opsomer |
Journal of Dairy Science | 2015 |
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Subchronic Sleep Restriction Causes Tissue-Specific Insulin Resistance
MN Rao, TC Neylan, C Grunfeld, K Mulligan, M Schambelan, JM Schwarz |
The Journal of clinical endocrinology and metabolism | 2015 |
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Histopathological changes in rat pancreas and skeletal muscle associated with high fat diet induced insulin resistance
MI Gulen, AG Bagla, O Yavuz, AA Hismiogullari |
Biotechnic & Histochemistry | 2015 |
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Compensatory responses of the insulin signaling pathway restore muscle glucose uptake following long-term denervation
ZJ Callahan, M Oxendine, JL Wheatley, C Menke, EA Cassell, A Bartos, PC Geiger, PJ Schaeffer |
Physiological Reports | 2015 |
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Maternal obesity in females born small: Pregnancy complications and offspring disease risk
D Mahizir, JF Briffa, DH Hryciw, GD Wadley, KM Moritz, ME Wlodek |
Molecular Nutrition & Food Research | 2015 |
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Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4
Y Wang, J Wang, Y Zhao, S Hu, D Shi, C Xue |
Journal of Bioscience and Bioengineering | 2015 |
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Clinical associations between metabolic syndrome and the development of microalbuminuria in Korean men
JH Ryoo, H Chun, HS Lee, E Suh, JM Choi, MG Kim, HC Shin, SK Park, CM Oh, TS Ko |
Diabetes Research and Clinical Practice | 2015 |
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Predicting of disease genes for gestational diabetes mellitus based on network and functional consistency
Q Zhang, M He, J Wang, S Liu, H Cheng, Y Cheng |
European Journal of Obstetrics & Gynecology and Reproductive Biology | 2015 |
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Obesity-induced miR-15b is linked causally to the development of insulin resistance through the repression of the insulin receptor in hepatocytes
WM Yang, HJ Jeong, SW Park, W Lee |
Molecular Nutrition & Food Research | 2015 |
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Are hepatic and soleus lipid content, assessed by magnetic resonance spectroscopy, associated with low birth weight or insulin resistance in a rural Indian population of healthy young men?
RS Livingstone, LG Grunnet, N Thomas, A Eapen, B Antonisamy, VR Mohan, R Spurgeon, ID Frank, IC Bygbjerg, A Vaag |
Diabetic Medicine | 2015 |
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Magnesium lithospermate B improves metabolic changes in high-fat diet-fed rats with metabolic syndrome
YJ Chen, YH Lo, YT Chen, NW Lai, NH Lin, TY Chung, WY Chen, JT Tzen |
Journal of Functional Foods | 2015 |
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Isolation and structural characterization of 2R, 3R taxifolin 3-O-rhamnoside from ethyl acetate extract of Hydnocarpus alpina and its hypoglycemic effect by attenuating hepatic key enzymes of glucose metabolism in streptozotocin-induced diabetic rats
R Balamurugan, SE Vendan, A Aravinthan, JH Kim |
Biochimie | 2015 |
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Trans-anethole, a terpenoid ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin induced diabetic rats
BA Sheikh, L Pari, A Rathinam, R Chandramohan |
Biochimie | 2015 |
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Low-glycemic index diet may improve insulin sensitivity in obese children
C Visuthranukul, P Sirimongkol, A Prachansuwan, C Pruksananonda, S Chomtho |
Pediatric Research | 2015 |
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Handbook of eggs in human function
KS Kubena |
Handbook of eggs in human function | 2015 |
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The cell size and distribution of adipocytes from subcutaneous and visceral fat is associated with type 2 diabetes mellitus in humans
L Fang, F Guo, L Zhou, R Stahl, J Grams |
Adipocyte | 2015 |
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Grip Strength as a Marker of Hypertension and Diabetes in Healthy Weight Adults
AG Mainous, RJ Tanner, SD Anton, A Jo |
American Journal of Preventive Medicine | 2015 |
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Prenatal exposure to persistent organochlorine pollutants is associated with high insulin levels in 5-year-old girls
JL Tang-Péronard, BL Heitmann, TK Jensen, AM Vinggaard, S Madsbad, U Steuerwald, P Grandjean, P Weihe, F Nielsen, HR Andersen |
Environmental Research | 2015 |
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Geranium oil ameliorates endothelial dysfunction in high fat high sucrose diet induced metabolic complications in rats
RP Kshirsagar, MV Kothamasu, MA Patil, GB Reddy, BD Kumar, PV Diwan |
Journal of Functional Foods | 2015 |
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A cohort study of incident microalbuminuria in relation to HOMA-IR in Korean men
SK Park, H Chun, JH Ryoo, SW Lee, HS Lee, KW Shim, CY Cho, DR Ryu, TS Ko, E Kim, SJ Park, JH Park, SJ Hong, HP Hong |
Clinica Chimica Acta | 2015 |
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Anti-inflammatory γ- and δ-tocotrienols improve cardiovascular, liver and metabolic function in diet-induced obese rats
WY Wong, LC Ward, CW Fong, WN Yap, L Brown |
European Journal of Nutrition | 2015 |
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Relationship of Circulating Fatty Acid Profile to Metabolic Disorders Associated with Insulin Resistance
L Kazdova |
EBioMedicine | 2015 |
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The genetics of lipid storage and human lipodystrophies
AL Robbins, DB Savage |
Trends in Molecular Medicine | 2015 |
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Insulin is an important risk factor of endometrial cancer among premenopausal women: a case-control study in China
Y Shao, S Cheng, J Hou, Y Zuo, W Zheng, M Xia, N Mu |
Tumor Biology | 2015 |
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Dietary selenate attenuates adiposity and improves insulin sensitivity in high-fat diet-induced obese mice
CY Kim, Y Zhu, KK Buhman, KH Kim |
Journal of Functional Foods | 2015 |
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Acquired partial lipodystrophy is associated with increased risk for developing metabolic abnormalities
B Akinci, FD Koseoglu, H Onay, S Yavuz, C Altay, IY Simsir, S Ozisik, L Demir, M Korkut, N Yilmaz, S Ozen, G Akinci, T Atik, M Calan, M Secil, A Comlekci, T Demir |
Metabolism | 2015 |
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Ameliorative properties of ethyl acetate fraction of Ceiba pentandra on serum glucose, hematological and biochemical parameters of diabetic rats
MH Lami, KA Yusuf, SA Ndaman, BM Bola, BO Damilola, AA Siddique |
Asian Pacific Journal of Tropical Disease | 2015 |
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UCP1-3826A>G polymorphism affects weight, fat mass and risk of type 2 diabetes mellitus in grade III obese patients
CF Nicoletti, AP de Oliveira, MJ Brochado, BP de Oliveira, MA de Pinhel, JS Marchini, JE Santos, W Salgado, WA Silva, CB Nonino |
Nutrition | 2015 |
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Casual serum triglyceride as a predictor of premature type 2 diabetes mellitus: an 8-year cohort study of middle-aged Japanese workers
T Nishikawa, T Okamura, A Shima, Y Kawatsu, D Sugiyama, A Kadota, A Morimoto, Y Tatsumi, K Godai, N Miyamatsu |
Diabetology International | 2015 |
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Postnatal high-fat diet enhances ectopic fat deposition in pigs with intrauterine growth retardation
H Yan, P Zheng, B Yu, J Yu, X Mao, J He, Z Huang, D Chen |
European Journal of Nutrition | 2015 |
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Myosteatosis increases with aging and is associated with incident diabetes in African ancestry men: Myosteatosis, Aging, and Diabetes Risk
I Miljkovic, AL Kuipers, R Cvejkus, CH Bunker, AL Patrick, CL Gordon, JM Zmuda |
Obesity | 2015 |
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Pyruvate kinase, muscle isoform 2 promotes proliferation and insulin secretion of pancreatic β-cells via activating Wnt/CTNNB1 signaling
Suijun Wang, Zhen Yang, Ying Gao, Quanzhong Li, Yong Su, Yanfang Wang, Yun Zhang, Hua Man, Hongxia Liu |
International journal of clinical and experimental pathology | 2015 |
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Multidisciplinary Approach to Obesity
N Napoli, P Pozzilli |
Multidisciplinary Approach to Obesity | 2015 |
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Handbook of Food Chemistry
PC Cheung, BM Mehta |
Handbook of Food Chemistry | 2015 |
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Effects of acute exercise on lipid content and dietary lipid uptake in liver and skeletal muscle of lean and diabetic rats
S Janssens, RA Jonkers, AK Groen, K Nicolay, LJ van Loon, JJ Prompers |
American journal of physiology. Endocrinology and metabolism | 2015 |
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Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism
MG Schooneman, GA Have, N Vlies, SM Houten, NE Deutz, MR Soeters |
American journal of physiology. Endocrinology and metabolism | 2015 |
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The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle fibers and reduces insulin resistance in obese mice
P Llanos, A Contreras-Ferrat, T Georgiev, C Osorio-Fuentealba, A Espinosa, J Hidalgo, C Hidalgo, E Jaimovich |
American journal of physiology. Endocrinology and metabolism | 2015 |
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Lifestyle and the Prevention of Type 2 Diabetes: A Status Report
KI Galaviz, KM Narayan, F Lobelo, MB Weber |
American journal of lifestyle medicine | 2015 |
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Effect of Chromium(III) -Amino acid (1:3)Complexes on High Sucrose Induced Insulin Resistance, Lipid Abnormalities and Oxidative Stress in Male Sprague Dawley Rats
R Manchala |
Journal of diabetes and obesity | 2015 |
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Preventive Nutrition: The Comprehensive Guide for Health Professionals
A Bendich, RJ Deckelbaum |
2015 | |
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Air Pollution and Health Effects
SS Nadadur, JW Hollingsworth |
2015 | |
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Innovative Medicine
K Nakao, N Minato, S Uemoto |
2015 | |
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Casual serum triglyceride as a predictor of premature type 2 diabetes mellitus: an 8-year cohort study of middle-aged Japanese workers.
Nishikawa T, Okamura T, Shima A, Kawatsu Y, Sugiyama D, Kadota A, Morimoto A, Tatsumi Y, Godai K, Miyamatsu N |
Diabetology International | 2015 |
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Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans
J Szendroedi, T Yoshimura, E Phielix, C Koliaki, M Marcucci, D Zhang, T Jelenik, J Müller, C Herder, P Nowotny, GI Shulman, M Roden |
Proceedings of the National Academy of Sciences | 2014 |
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Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes
AL Birkenfeld, GI Shulman |
Hepatology | 2014 |
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PCAF Improves Glucose Homeostasis by Suppressing the Gluconeogenic Activity of PGC-1α
C Sun, M Wang, X Liu, L Luo, K Li, S Zhang, Y Wang, Y Yang, F Ding, X Gu |
2014 | |
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The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
RJ Perry, VT Samuel, KF Petersen, GI Shulman |
Nature | 2014 |
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Potent Effects of the Total Saponins from Dioscorea nipponica Makino Against Streptozotocin-Induced Type 2 Diabetes Mellitus in Rats: ROLE OF TSDN IN TYPE 2 DIABETES MELLITUS
H Yu, L Zheng, L Xu, L Yin, Y Lin, H Li, K Liu, J Peng |
Phytotherapy Research | 2014 |
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Intracellular lipid accumulation and shift during diabetes progression
P Wolf, Y Winhofer, CH Anderwald, M Krššák, M Krebs |
Wiener Medizinische Wochenschrift | 2014 |
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Elevated hepatic 11 -hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia
A Chapagain, PW Caton, J Kieswich, P Andrikopoulos, N Nayuni, JH Long, SM Harwood, SP Webster, MJ Raftery, C Thiemermann, BR Walker, JR Seckl, R Corder, MM Yaqoob |
Proceedings of the National Academy of Sciences | 2014 |
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Estradiol regulates insulin signaling and inflammation in adipose tissue
M Shen, SP Kumar, H Shi |
Hormone Molecular Biology and Clinical Investigation | 2014 |
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Predictors of Ectopic Fat in Humans
M Zamboni, AP Rossi, F Fantin, SL Budui, E Zoico, GA Zamboni, G Mazzali |
Current Obesity Reports | 2014 |
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Lower body adipose tissue removal decreases glucose tolerance and insulin sensitivity in mice with exposure to high fat diet
K Cox-York, Y Wei, D Wang, MJ Pagliassotti, MT Foster |
Adipocyte | 2014 |
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A link between hepatic glucose production and peripheral energy metabolism via hepatokines
A Abdul-Wahed, A Gautier-Stein, S Casteras, M Soty, D Roussel, C Romenstaing, H Guillou, JA Tourette, N Pleche, C Zitoun, B Gri, A Sardella, F Rajas, G Mithieux |
Molecular Metabolism | 2014 |
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Pulmonary Arterial Hypertension and Insulin Resistance
DB Bradley |
Journal of molecular and genetic medicine : an international journal of biomedical research | 2014 |
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The Production of Nitric Oxide, IL-6, and TNF-Alpha in Palmitate-Stimulated PBMNCs Is Enhanced through Hyperglycemia in Diabetes
CM Volpe, LF Abreu, PS Gomes, RM Gonzaga, CA Veloso, JA Nogueira-Machado |
Oxidative Medicine & Cellular Longevity | 2014 |
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Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation
LS Chow, DG Mashek, E Austin, LE Eberly, XM Persson, MT Mashek, ER Seaquist, MD Jensen |
American journal of physiology. Endocrinology and metabolism | 2014 |
|
Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12
H Cheon, Y Cho |
Journal of Biomedical Science | 2014 |
|
Treatment with the 3-Ketoacyl-CoA Thiolase Inhibitor Trimetazidine Does Not Exacerbate Whole-Body Insulin Resistance in Obese Mice
JR Ussher, W Keung, N Fillmore, TR Koves, J Mori, L Zhang, DG Lopaschuk, OR Ilkayeva, CS Wagg, JS Jaswal, DM Muoio, GD Lopaschuk |
The Journal of pharmacology and experimental therapeutics | 2014 |
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Fatty acid sensing in the gut and the hypothalamus: In vivo and in vitro perspectives
FA Duca, JT Yue |
Molecular and Cellular Endocrinology | 2014 |
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Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance
MJ Hanssen, R Wierts, J Hoeks, A Gemmink, B Brans, FM Mottaghy, P Schrauwen, WD van Lichtenbelt |
Diabetologia | 2014 |
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Saturated fatty acid-induced miR-195 impairs insulin signaling and glycogen metabolism in HepG2 cells
WM Yang, HJ Jeong, SY Park, W Lee |
FEBS Letters | 2014 |
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Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity in steroid induced insulin resistant rats
YI Chen, YW Cheng, CY Tzeng, YC Lee, YN Chang, SC Lee, CC Tsai, JC Chen, JT Tzen, SL Chang |
BMC complementary and alternative medicine | 2014 |
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Muscle-specific activation of Ca2+/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice
HY Lee, AK Gattu, JP Camporez, S Kanda, B Guigni, M Kahn, D Zhang, T Galbo, AL Birkenfeld, FR Jornayvaz, MJ Jurczak, CS Choi, Z Yan, RS Williams, GI Shulman, VT Samuel |
Diabetologia | 2014 |
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The Negative Effects of Obesity and Poor Glycemic Control on Cognitive Function: A Proposed Model for Possible Mechanisms
ML Alosco, J Gunstad |
Current Diabetes Reports | 2014 |
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High-fat diet from perilla oil induces insulin resistance despite lower serum lipids and increases hepatic fatty acid oxidation in rats
T Zhang, S Zhao, W Li, L Ma, M Ding, R Li, Y Liu |
Lipids in Health and Disease | 2014 |
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The Chinese herbal medicine FTZ attenuates insulin resistance via IRS1 and PI3K in vitro and in rats with metabolic syndrome
X Hu, M Wang, W Bei, Z Han, J Guo |
Journal of Translational Medicine | 2014 |
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Association Between the Hypertriglyceridemic Waist Phenotype, Prediabetes, and Diabetes Mellitus Among Adults in Puerto Rico
MV Díaz-Santana, EL Pérez, AP Martínez, MG Serrano, CM Cardona |
Journal of Immigrant and Minority Health | 2014 |
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Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats
MM Amin, GF Asaad, RM Salam, HS El-Abhar, MS Arbid |
PloS one | 2014 |
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Handbook of Nutrition, Diet and the Eye
W Abbott-Johnson, P Kerlin |
Handbook of Nutrition, Diet and the Eye | 2014 |
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Rosmarinic acid, a polyphenol, ameliorates hyperglycemia by regulating the key enzymes of carbohydrate metabolism in high fat diet – STZ induced experimental diabetes mellitus
G Jayanthy, S Subramanian |
Biomedicine & Preventive Nutrition | 2014 |
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Handbook of Obesity: Epidemology, Etiology, and Physiopathology
N Assad, J Alvarado, A Sood |
Handbook of Obesity: Epidemology, Etiology, and Physiopathology | 2014 |
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Diabetes mellitus and medicinal plants-a review
S Surya, AD Salam, DV Tomy, B Carla, RA Kumar, C Sunil |
Asian Pacific Journal of Tropical Disease | 2014 |
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Gestational Diabetes: Origins, Complications, and Treatment
X Chen, T Scholl |
Gestational Diabetes: Origins, Complications, and Treatment | 2014 |
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Organophosphorus insecticide, monocrotophos, possesses the propensity to induce insulin resistance in rats on chronic exposure: Monocrotophos induces insulin resistance in rats
R Nagaraju, AK Joshi, PS Rajini |
Journal of Diabetes | 2014 |
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Systemic and characteristic metabolites in the serum of streptozotocin-induced diabetic rats at different stages as revealed by a 1H-NMR based metabonomic approach
C Diao, L Zhao, M Guan, Y Zheng, M Chen, Y Yang, L Lin, W Chen, H Gao |
Molecular BioSystems | 2014 |
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The AMPK-SIRT signaling network regulates glucose tolerance under calorie restriction conditions
MF Silvestre, B Viollet, PW Caton, J Leclerc, I Sakakibara, M Foretz, MC Holness, MC Sugden |
Life Sciences | 2014 |
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Effect of tangeretin, a polymethoxylated flavone on glucose metabolism in streptozotocin-induced diabetic rats
R Sundaram, P Shanthi, P Sachdanandam |
Phytomedicine | 2014 |
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Oleanolic acid supplement attenuates liquid fructose-induced adipose tissue insulin resistance through the insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt signaling pathway in rats
Y Li, J Wang, T Gu, J Yamahara, Y Li |
Toxicology and Applied Pharmacology | 2014 |
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Antidiabetic effect of Lactobacillus casei CCFM0412 in high-fat-fed, streptozotocin-induced type 2 diabetic mice
P Chen, Q Zhang, H Dang, X Liu, F Tian, J Zhao, Y Chen, H Zhang, W Chen |
Nutrition | 2014 |
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Emerging micro- and nanotechnology based synthetic approaches for insulin delivery
R Mo, T Jiang, J Di, W Tai, Z Gu |
Chemical Society Reviews | 2014 |
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Correlations between A1c, fasting glucose, 2h postload glucose, and β-cell function in the Chinese population
C Li, H Yang, G Tong, S Shen, W Feng, Y Bi, D Zhu |
Acta Diabetologica | 2014 |
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Anti-diabetic effect of a novel N-Trisaccharide isolated from Cucumis prophetarum on streptozotocin–nicotinamide induced type 2 diabetic rats
GB Kavishankar, N Lakshmidevi |
Phytomedicine | 2014 |
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Effect of multispecies probiotic supplements on serum minerals, liver enzymes and blood pressure in patients with type 2 diabetes
Z Asemi, S Bahmani, H Shakeri, A Jamal, AM Faraji |
International Journal of Diabetes in Developing Countries | 2014 |
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Lipopolysaccharide impairs insulin sensitivity via activation of phosphoinositide 3-kinase in adipocytes
S Wakayama, A Haque, N Koide, Y Kato, E Odkhuu, T Bilegtsaikhan, Y Naiki, T Komatsu, T Yoshida, T Yokochi |
Immunopharmacology and Immunotoxicology | 2014 |
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Marrow fat composition in anorexia nervosa
MA Bredella, PK Fazeli, SM Daley, KK Miller, CJ Rosen, A Klibanski, M Torriani |
Bone | 2014 |
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The effect of metformin treatment in vivo on acute and long-term energy metabolism and progesterone production in vitro by granulosa cells from women with polycystic ovary syndrome
D Maruthini, SE Harris, JH Barth, AH Balen, BK Campbell, HM Picton |
Human Reproduction | 2014 |
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Acute insulin resistance stimulates and insulin sensitization attenuates vascular smooth muscle cell migration and proliferation
E Cersosimo, X Xu, S Upala, C Triplitt, N Musi |
Physiological Reports | 2014 |
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Rapid Deterioration of Insulin Secretion in Obese Adolescents Preceding the Onset of Type 2 Diabetes
DA Elder, LN Hornung, PM Herbers, R Prigeon, JG Woo, DA D'Alessio |
The Journal of Pediatrics | 2014 |
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Blood glucose management in the patient undergoing cardiac surgery: A review
P Reddy |
World journal of cardiology | 2014 |
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Delayed Skeletal Muscle Mitochondrial ADP Recovery in Youth With Type 1 Diabetes Relates to Muscle Insulin Resistance
M Cree-Green, BR Newcomer, MS Brown, AD Baumgartner, B Bergman, B Drew, JG Regensteiner, L Pyle, JE Reusch, KJ Nadeau |
Diabetes | 2014 |
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The Synergistic Effects of HIV, Diabetes, and Aging on Cognition: Implications for Practice and Research
DE Vance, PL Fazeli, JE Dodson, M Ackerman, M Talley, SJ Appel |
Journal of Neuroscience Nursing | 2014 |
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Diabétologie
JL Schlienger |
Diabetologie und Stoffwechsel | 2014 |
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Regulation of Diacylglycerol Kinase δ2 Expression in C2C12 Skeletal Muscle Cells by Free Fatty Acids
S Sakiyama, T Usuki, H Sakai, F Sakane |
Lipids | 2014 |
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Carnitine Metabolism and Human Nutrition
S Wicks, R Noland, R Mynatt |
Carnitine Metabolism and Human Nutrition | 2014 |
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Fucoidan from sea cucumber protects against high-fat high-sucrose diet-induced hyperglycaemia and insulin resistance in mice
S Hu, G Xia, J Wang, Y Wang, Z Li, C Xue |
Journal of Functional Foods | 2014 |
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Effects of spinal cord injury on body composition and metabolic profile – Part I
AS Gorgey, DR Dolbow, JD Dolbow, RK Khalil, C Castillo, DR Gater |
The journal of spinal cord medicine | 2014 |
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4-Hydroxyisoleucine ameliorates fatty acid-induced insulin resistance and inflammatory response in skeletal muscle cells
CK Maurya, R Singh, N Jaiswal, K Venkateswarlu, T Narender, AK Tamrakar |
Molecular and Cellular Endocrinology | 2014 |
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Effect of biologically synthesized gold nanoparticles on alloxan-induced diabetic rats—An in vivo approach
V Karthick, VG Kumar, TS Dhas, G Singaravelu, AM Sadiq, K Govindaraju |
Colloids and Surfaces B: Biointerfaces | 2014 |
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Insulin and GH–IGF-I axis: endocrine pacer or endocrine disruptor?
A Giustina, R Berardelli, C Gazzaruso, G Mazziotti |
Acta Diabetologica | 2014 |
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Novel CoQ10 Antidiabetic Mechanisms Underlie Its Positive Effect: Modulation of Insulin and Adiponectine Receptors, Tyrosine Kinase, PI3K, Glucose Transporters, sRAGE and Visfatin in Insulin Resistant/Diabetic Rats
MM Amin, GF Asaad, RM Salam, HS El-Abhar, MS Arbid, C Miele |
PloS one | 2014 |
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A polyphenol rescues lipid induced insulin resistance in skeletal muscle cells and adipocytes
B Gogoi, P Chatterjee, S Mukherjee, AK Buragohain, S Bhattacharya, S Dasgupta |
Biochemical and Biophysical Research Communications | 2014 |
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GFT505 for the treatment of nonalcoholic steatohepatitis and type 2 diabetes
B Cariou, B Staels |
Expert Opinion on Investigational Drugs | 2014 |
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Melatonin: Therapeutic Value and Neuroprotection
V Srinivasan, Y Ohta, J Espino, R Zakaria, M Mohamed |
Melatonin: Therapeutic Value and Neuroprotection | 2014 |
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Nuclear factor-κB is a common upstream signal for growth differentiation factor-5 expression in brown adipocytes exposed to pro-inflammatory cytokines and palmitate
E Hinoi, T Iezaki, K Ozaki, Y Yoneda |
Biochemical and Biophysical Research Communications | 2014 |
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Proteins and bioactive peptides: Mechanisms of action on diabetes management
ME Oseguera-Toledo, EG de Mejía, R Reynoso-Camacho, A Cardador-Martínez, SL Amaya-Llano |
Nutrafoods | 2014 |
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Swimming improves high-fat induced insulin resistance by regulating lipid and energy metabolism and the insulin pathway in rats
AN SONG, C Wang, L Ren, J Zhao |
International journal of molecular medicine | 2014 |
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Reduced skeletal muscle AMPK and mitochondrial markers do not promote age-induced insulin resistance
AL Bujak, RM Blümer, K Marcinko, MD Fullerton, BE Kemp, GR Steinberg |
Journal of applied physiology | 2014 |
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Increased skeletal muscle capillarization enhances insulin sensitivity
T Akerstrom, L Laub, K Vedel, CL Brand, BK Pedersen, AK Lindqvist, JF Wojtaszewski, Y Hellsten |
American journal of physiology. Endocrinology and metabolism | 2014 |
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Oxidative Stress Mechanisms and their Modulation
M Bansal, N Kaushal |
2014 | |
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Treatment of the Obese Patient
RF Kushner, DH Bessesen |
2014 | |
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Metabolic Syndrome: A Comprehensive Textbook
RS Ahima |
Metabolic Syndrome | 2014 |
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Morbid Obesity in Adolescents
K Widhalm, G Prager |
2014 | |
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Distinct metabolic effects following short-term exposure of different high-fat diets in male and female mice
SP Kumar, M Shen, EG Spicer, AJ Goudjo-Ako, JD Stumph, J Zhang, H Shi |
Endocrine Journal | 2014 |
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Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
IA Bondar', AA Demin, OY Shabel'nikova |
Diabetes mellitus | 2014 |
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Effect of Coptidis Rhizoma extracts in a water-based solution on insulin resistance in 3T3-L1 adipocytes
Y YUAN, X WANG, X LU, Y MARUNAKA, X WANG |
Biomedical Research | 2014 |
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Recreational physical activity is inversely associated with asymptomatic gallstones in adult Mexican women
S Henao-Morán, E Denova-Gutiérrez, S Morán, X Duque, K Gallegos-Carrillo, N Macias, J Salmerón |
ANN HEPATOL | 2014 |
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Regulation of diacylglycerol kinase δ2 expression in C2C12 skeletal muscle cells by free fatty acids.
Sakiyama S, Usuki T, Sakai H, Sakane F |
Lipids | 2014 |
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Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans
BS Maciejewski, JL LaPerle, D Chen, A Ghosh, WJ Zavadoski, TS McDonald, TB Manion, D Mather, TA Patterson, M Hanna, S Watkins, EM Gibbs, RA Calle, CM Steppan |
American journal of physiology. Gastrointestinal and liver physiology | 2013 |
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Raised serum adenosine deaminase level in nonobese type 2 diabetes mellitus
VK Khemka, D Bagchi, A Ghosh, O Sen, A Bir, S Chakrabarti, A Banerjee |
The Scientific World JOURNAL | 2013 |
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Mechanisms of insulin resistance in obesity
J Ye |
Frontiers of Medicine | 2013 |
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Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I
F Paneni, JA Beckman, MA Creager, F Cosentino |
European Heart Journal | 2013 |
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Populus balsamifera Extract and Its Active Component Salicortin Reduce Obesity and Attenuate Insulin Resistance in a Diet-Induced Obese Mouse Model
D Harbilas, D Vallerand, A Brault, A Saleem, JT Arnason, L Musallam, PS Haddad |
Evidence-Based Complementary and Alternative Medicine | 2013 |
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Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes
K Cai, MB Sewer |
Biochemical Journal | 2013 |
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
JM Kristensen, S Larsen, JW Helge, F Dela, JF Wojtaszewski |
PloS one | 2013 |
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Insulin resistance protects the heart from fuel overload in dysregulated metabolic states
H Taegtmeyer, C Beauloye, R Harmancey, L Hue |
American journal of physiology. Heart and circulatory physiology | 2013 |
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Leptin Engages a Hypothalamic Neurocircuitry to Permit Survival in the Absence of Insulin
T Fujikawa, ED Berglund, VR Patel, G Ramadori, CR Vianna, L Vong, F Thorel, S Chera, PL Herrera, BB Lowell, JK Elmquist, P Baldi, R Coppari |
Cell Metabolism | 2013 |
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Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice
S Burghoff, U Flögel, S Bongardt, V Burkart, H Sell, S Tucci, K Ikels, D Eberhard, M Kern, N Klöting, J Eckel, J Schrader |
Archives Of Physiology And Biochemistry | 2013 |
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Rutin Suppresses Palmitic Acids-Triggered Inflammation in Macrophages and Blocks High Fat Diet-Induced Obesity and Fatty Liver in Mice
M Gao, Y Ma, D Liu |
Pharmaceutical Research | 2013 |
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A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
M Okada-Iwabu, T Yamauchi, M Iwabu, T Honma, K Hamagami, K Matsuda, M Yamaguchi, H Tanabe, T Kimura-Someya, M Shirouzu, H Ogata, K Tokuyama, K Ueki, T Nagano, A Tanaka, S Yokoyama, T Kadowaki |
Nature | 2013 |
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Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies
MA McArdle, OM Finucane, RM Connaughton, AM McMorrow, HM Roche |
Frontiers in Endocrinology | 2013 |
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Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism
F Magkos, D Bradley, GG Schweitzer, BN Finck, JC Eagon, O Ilkayeva, CB Newgard, S Klein |
Diabetes | 2013 |
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MicroRNA-494, upregulated by tumor necrosis factor-α, desensitizes insulin effect in C2C12 muscle cells
H Lee, Y Jee, K Hong, GS Hwang, KH Chun |
PloS one | 2013 |
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Dietary Omega-3 Fatty Acid Deficiency and High Fructose Intake in the Development of Metabolic Syndrome Brain, Metabolic Abnormalities, and Non-Alcoholic Fatty Liver Disease
A Simopoulos |
Nutrients | 2013 |
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Cardiometabolic interventions - focus on transcriptional regulators
JT Chai, RP Choudhury |
The European journal of cardiovascular medicine | 2013 |
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Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice
JP Camporez, FR Jornayvaz, MC Petersen, D Pesta, BA Guigni, J Serr, D Zhang, M Kahn, VT Samuel, MJ Jurczak, GI Shulman |
Endocrinology | 2013 |
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Lipid in skeletal muscle myotubes is associated to the donors' insulin sensitivity and physical activity phenotypes
S Bajpeyi, CK Myrland, JD Covington, D Obanda, WT Cefalu, SR Smith, AC Rustan, E Ravussin |
Obesity | 2013 |
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Markers of Skeletal Muscle Mitochondrial Function and Lipid Accumulation Are Moderately Associated with the Homeostasis Model Assessment Index of Insulin Resistance in Obese Men
IA Samjoo, A Safdar, MJ Hamadeh, AW Glover, NJ Mocellin, J Santana, JP Little, GR Steinberg, S Raha, MA Tarnopolsky |
PloS one | 2013 |
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Mitofusion-2-mediated alleviation of insulin resistance in rats through reduction in lipid intermediate accumulation in skeletal muscle
X Zhang, C Wang, G Song, K Gan, D Kong, Q Nie, L Ren |
Journal of Biomedical Science | 2013 |
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Physical activity is associated with retained muscle metabolism in human myotubes challenged with palmitate: Physical inactivity: effects on metabolism of muscle stem cells
CJ Green, T Bunprajun, BK Pedersen, C Scheele |
The Journal of Physiology | 2013 |
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Synergy in Free Radical Generation is Blunted by High-Fat Diet Induced Alterations in Skeletal Muscle Mitochondrial Metabolism
Y Li, V Periwal |
Biophysical Journal | 2013 |
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Mitochondrial Deficiency Is Associated With Insulin Resistance
BH Goodpaster |
Diabetes | 2013 |
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The Metabolic and Endocrine Response and Health Implications of Consuming Sugar-Sweetened Beverages: Findings From Recent Randomized Controlled Trials
JM Rippe |
Advances in nutrition (Bethesda, Md.) | 2013 |
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Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice
C Owen, EK Lees, L Grant, DJ Zimmer, N Mody, KK Bence, M Delibegović |
Diabetologia | 2013 |
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Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance
E Xu, M Schwab, A Marette |
Reviews in Endocrine and Metabolic Disorders | 2013 |
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CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance
JL Cantley, T Yoshimura, JP Camporez, D Zhang, FR Jornayvaz, N Kumashiro, F Guebre-Egziabher, MJ Jurczak, M Kahn, BA Guigni, J Serr, J Hankin, RC Murphy, GW Cline, S Bhanot, VP Manchem, JM Brown, VT Samuel, GI Shulman |
Proceedings of the National Academy of Sciences | 2013 |
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The Role of INDY in Metabolic Regulation
DM Willmes, AL Birkenfeld |
Computational and Structural Biotechnology Journal | 2013 |
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Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler
RJ Perry, T Kim, XM Zhang, HY Lee, D Pesta, VB Popov, D Zhang, Y Rahimi, MJ Jurczak, GW Cline, DA Spiegel, GI Shulman |
Cell Metabolism | 2013 |
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Measurements of diacylglycerols in skeletal muscle by atmospheric pressure chemical ionization mass spectrometry.
Lee SY, Kim JR, Ha MY, Shim SM, Park TS |
Lipids | 2013 |
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Protein kinase Cη is targeted to lipid droplets.
Suzuki M, Iio Y, Saito N, Fujimoto T |
Histochemistry and Cell Biology | 2013 |
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Translational Endocrinology of Bone
S Bhatt, RN Kulkarni |
Translational Endocrinology of Bone | 2013 |
|
Microvascular dysfunction: An emerging pathway in the pathogenesis of obesity-related insulin resistance
DM Muris, AJ Houben, MT Schram, CD Stehouwer |
Reviews in Endocrine and Metabolic Disorders | 2013 |
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Role of microangiopathy in diabetic cardiomyopathy
A Adameova, NS Dhalla |
Heart Failure Reviews | 2013 |
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Diabetes Mellitus and Inflammation
E Lontchi-Yimagou, E Sobngwi, TE Matsha, AP Kengne |
Current Diabetes Reports | 2013 |
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Clues from Bariatric Surgery: Reversing Insulin Resistance to Heal the Heart
KI Khalaf, H Taegtmeyer |
Current Diabetes Reports | 2013 |
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Haloperidol and olanzapine mediate metabolic abnormalities through different molecular pathways
V Mondelli, C Anacker, AC Vernon, A Cattaneo, S Natesan, M Modo, P Dazzan, S Kapur, CM Pariante |
Translational Psychiatry | 2013 |
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Human hippocampal energy metabolism is impaired during cognitive activity in a lipid infusion model of insulin resistance
Y Emmanuel, LE Cochlin, DJ Tyler, CA de Jager, AD Smith, K Clarke |
Brain and Behavior | 2013 |
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Acute psychological stress results in the rapid development of insulin resistance
L Li, X Li, W Zhou, JL Messina |
Journal of Endocrinology | 2013 |
|
Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase
AJ Ruiz-Alcaraz, C Lipina, JR Petrie, MJ Murphy, AD Morris, C Sutherland, DJ Cuthbertson |
PloS one | 2013 |
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PKCθ over expression in the central nucleus of the amygdala or hypothalamus has differential effects on energy balance and peripheral glucose homeostasis
MJ Park-York, S Boghossian, H Oh, DA York |
Brain Research | 2013 |
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Metabolic Dysfunction in Diabetic Offspring: Deviations in Metabolic Flexibility
RD Russell, RR Kraemer, AG Nelson |
Medicine and Science in Sports and Exercise | 2013 |
|
A newly identified polysaccharide from Ganoderma atrum attenuates hyperglycemia and hyperlipidemia
K Zhu, S Nie, C Li, S Lin, M Xing, W Li, D Gong, M Xie |
International Journal of Biological Macromolecules | 2013 |
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Protein kinase Cη is targeted to lipid droplets
M Suzuki, Y Iio, N Saito, T Fujimoto |
Histochemistry and Cell Biology | 2013 |
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Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice
S Muthulakshmi, R Saravanan |
Biochimie | 2013 |
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Measurements of Diacylglycerols in Skeletal Muscle by Atmospheric Pressure Chemical Ionization Mass Spectrometry
SY Lee, JR Kim, MY Ha, SM Shim, TS Park |
Lipids | 2013 |
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The Origins and Drivers of Insulin Resistance
AM Johnson, JM Olefsky |
Cell | 2013 |
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Non-Alcoholic Fatty Liver Disease: A Practical Guide
T Yokoo, A Tang, CB Sirlin |
Non-Alcoholic Fatty Liver Disease: A Practical Guide | 2013 |
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Muscle insulin resistance resulting from impaired microvascular insulin sensitivity in Sprague Dawley rats
D Premilovac, EA Bradley, HL Ng, SM Richards, S Rattigan, MA Keske |
Cardiovascular Research | 2013 |
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Modulatory effect of green tea extract on hepatic key enzymes of glucose metabolism in streptozotocin and high fat diet induced diabetic rats
R Sundaram, R Naresh, P Shanthi, P Sachdanandam |
Phytomedicine | 2013 |
|
Berberine improves insulin resistance in cardiomyocytes via activation of 5′-adenosine monophosphate-activated protein kinase
W Chang, M Zhang, J Li, Z Meng, S Wei, H Du, L Chen, GM Hatch |
Metabolism | 2013 |
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Quercetin and quercetin-3- O -glucuronide are equally effective in ameliorating endothelial insulin resistance through inhibition of reactive oxygen species-associated inflammation
XD Guo, DY Zhang, XJ Gao, J Parry, K Liu, BL Liu, M Wang |
Molecular Nutrition & Food Research | 2013 |
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Cardiovascular Diseases: Nutritional and Therapeutic Interventions
S Jana, S Swarnakar |
Cardiovascular Diseases: Nutritional and Therapeutic Interventions | 2013 |
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Doxycycline-regulated 3T3-L1 preadipocyte cell line with inducible, stable expression of adenoviral E4orf1 gene: a cell model to study insulin-independent glucose disposal
R Krishnapuram, EJ Dhurandhar, O Dubuisson, V Hegde, NV Dhurandhar |
PloS one | 2013 |
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Maternal and In Utero Determinants of Type 2 Diabetes Risk in the Young
KD Bruce |
Current Diabetes Reports | 2013 |
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Ectopic and Serum Lipid Levels Are Positively Associated with Bone Marrow Fat in Obesity
MA Bredella, CM Gill, AV Gerweck, MG Landa, V Kumar, SM Daley, M Torriani, KK Miller |
Radiology | 2013 |
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Resistance training for diabetes prevention and therapy: experimental findings and molecular mechanisms
B Strasser, D Pesta |
BioMed Research International | 2013 |
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Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration
L Lukjanenko, S Brachat, E Pierrel, E Lach-Trifilieff, JN Feige |
PloS one | 2013 |
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Association of lifecourse socioeconomic status with chronic inflammation and type 2 diabetes risk: the Whitehall II prospective cohort study
S Stringhini, GD Batty, P Bovet, MJ Shipley, MG Marmot, M Kumari, AG Tabak, M Kivimäki |
PLoS Medicine | 2013 |
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Lower maternal body condition during pregnancy affects skeletal muscle structure and glut-4 protein levels but not glucose tolerance in mature adult sheep
PM Costello, LJ Hollis, RL Cripps, N Bearpark, HP Patel, AA Sayer, C Cooper, MA Hanson, SE Ozanne, LR Green |
Reproductive sciences (Thousand Oaks, Calif.) | 2013 |
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PKCθ expression in the amygdala regulates insulin signaling, food intake and body weight
MJ Park-York, S Boghossian, H Oh, DA York |
Obesity | 2013 |
|
Consumption of sucrose and high-fructose corn syrup does not increase liver fat or ectopic fat deposition in muscles
S Bravo, J Lowndes, S Sinnett, Z Yu, J Rippe |
Applied Physiology, Nutrition, and Metabolism | 2013 |
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Influence of glucocorticoids and growth hormone on insulin sensitivity in humans
KC Yuen, LE Chong, MC Riddle |
Diabetic Medicine | 2013 |
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Animal Models for the Study of Human Disease
HA Lawson |
Animal Models for the Study of Human Disease | 2013 |
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Antioxidant and anti-inflammatory effects of quercetin in functional and morphological alterations in streptozotocin-induced diabetic rats
RM Maciel, MM Costa, DB Martins, RT França, R Schmatz, DL Graça, MM Duarte, CC Danesi, CM Mazzanti, MR Schetinger, FC Paim, HE Palma, FH Abdala, N Stefanello, CK Zimpel, DV Felin, ST Lopes |
Research in Veterinary Science | 2013 |
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GSK256073, a selective agonist of G-protein coupled receptor 109A (GPR109A) reduces serum glucose in subjects with type 2 diabetes mellitus
RL Dobbins, SP Shearn, RL Byerly, FF Gao, KM Mahar, A Napolitano, GJ Nachbaur, AC le de Gouville |
Diabetes, Obesity and Metabolism | 2013 |
|
Piperine Reverses High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice
S Choi, Y Choi, Y Choi, S Kim, J Jang, T Park |
Food Chemistry | 2013 |
|
Kiwifruit (Actinidia chinensis) extract annuls chronic insulininduced insulin resistance in l6 skeletal muscle cells
JH Kim, JW Kim, SC Kim, YJ Lee |
Food Science and Biotechnology | 2013 |
|
Fitness, nutrition and the molecular basis of chronic disease
CP McAtee |
Biotechnology & genetic engineering reviews | 2013 |
|
Mitochondrial dysfunction in nonalcoholic fatty liver disease and insulin resistance: Cause or consequence?
C Garcia-Ruiz, A Baulies, M Mari, PM Garcia-Roves, JC Fernandez-Chace |
Free Radical Research | 2013 |
|
Equine Clinical Pathology: Walton/Equine
RM Walton |
Equine Clinical Pathology: Walton/Equine | 2013 |
|
Practicable Measures and Indices of Insulin Resistance in Nutrition Research
JG Hattersley, MO Weickert |
Current Obesity Reports | 2013 |
|
Metabolic Syndrome and Neurological Disorders: Farooqui/Metabolic
AA Farooqui, T Farooqui |
Metabolic Syndrome and Neurological Disorders: Farooqui/Metabolic | 2013 |
|
Molecular mechanisms of the alternative lipogenic function of insulin
YA Pankov |
Molecular Biology | 2013 |
|
Piperazine Oxadiazole Inhibitors of Acetyl-CoA Carboxylase
MP Bourbeau, A Siegmund, JG Allen, H Shu, C Fotsch, MD Bartberger, KW Kim, R Komorowski, M Graham, J Busby, M Wang, J Meyer, Y Xu, K Salyers, M Fielden, MM Véniant, W Gu |
Journal of Medicinal Chemistry | 2013 |
|
Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant mice
S Hu, Y Chang, J Wang, C Xue, D Shi, H Xu, Y Wang |
Food & Function | 2013 |
|
Modifiable risk factors in periodontitis: at the intersection of aging and disease
MA Reynolds |
Periodontology 2000 | 2013 |
|
Synthesis and blood glucose lowering activity of some novel benzenesulfonylthiourea derivatives substituted with 4-aryl-1-oxophthalazin-2(1H)yl-ones
S Yaseen, R Bashir, S Ovais, P Rathore, M Samim, K Javed |
Journal of Enzyme Inhibition and Medicinal Chemistry | 2013 |
|
Protective effects of tocotrienols against lipid-induced nephropathy in experimental type-2 diabetic rats by modulation in TGF-β expression
S Siddiqui, H Ahsan, MR Khan, WA Siddiqui |
Toxicology and Applied Pharmacology | 2013 |
|
The effect of high fat diet and saturated fatty acids on insulin signaling in the amygdala and hypothalamus of rats
H Oh, S Boghossian, DA York, MJ Park-York |
Brain Research | 2013 |
|
Lipid-induced hepatic insulin resistance
T Galbo, GI Shulman |
Aging | 2013 |
|
Effects of spectral transmittance through standard laboratory cages on circadian metabolism and physiology in nude rats
RT Dauchy, EM Dauchy, JP Hanifin, SL Gauthreaux, L Mao, VP Belancio, TG Ooms, LM Dupepe, MR Jablonski, B Warfield, MA Wren, GC Brainard, SM Hill, DE Blask |
Journal of the American Association for Laboratory Animal Science : JAALAS | 2013 |
|
Intramyocellular diacylglycerol concentrations and [U-¹³C]palmitate isotopic enrichment measured by LC/MS/MS
AU Blachnio-Zabielska, P Zabielski, MD Jensen |
Journal of lipid research | 2013 |
|
The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes
C Chitraju, M Trötzmüller, J Hartler, H Wolinski, GG Thallinger, G Haemmerle, R Zechner, R Zimmermann, HC Köfeler, F Spener |
Journal of lipid research | 2013 |
|
Glucose-6-Phosphate-Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
A Wilamowitz-Moellendorff, RW Hunter, M Garcia-Rocha, L Kang, I Lopez-Soldado, L Lantier, K Patel, MW Peggie, C Martinez-Pons, M Voss, J Calbo, PT Cohen, DH Wasserman, JJ Guinovart, K Sakamoto |
Diabetes | 2013 |
|
Blocking the Entrance to Open the Gate
P Schrauwen, S Timmers, MK Hesselink |
Diabetes | 2013 |
|
Dual Peroxisome Proliferator-Activated Receptor / Agonist GFT505 Improves Hepatic and Peripheral Insulin Sensitivity in Abdominally Obese Subjects
B Cariou, R Hanf, S Lambert-Porcheron, Y Zair, V Sauvinet, B Noel, L Flet, H Vidal, B Staels, M Laville |
Diabetes care | 2013 |
|
Defective Adipose Lipolysis and Altered Global Energy Metabolism in Mice with Adipose Overexpression of the Lipolytic Inhibitor G0/G1 Switch Gene 2 (G0S2)
BL Heckmann, X Zhang, X Xie, A Saarinen, X Lu, X Yang, J Liu |
The Journal of biological chemistry | 2013 |
|
An approach to the etiology of metabolic syndrome
AM Contreras, GB Berrío, CM R |
COLOMB MEDICA | 2013 |
|
Long-Term Treatment with an Herbal Formula MCC Reduces the Weight Gain in High Fat Diet-Induced Obese Mice
PK Leong, HY Leung, HS Wong, J Chen, CW Ma, Y Yang, KM Ko |
Chinese medicine | 2013 |
|
MicroRNA-494, Upregulated by Tumor Necrosis Factor-α, Desensitizes Insulin Effect in C2C12 Muscle Cells
H Lee, Y Jee, K Hong, GS Hwang, KH Chun, M Kanzaki |
PloS one | 2013 |
|
Markers of Skeletal Muscle Mitochondrial Function and Lipid Accumulation Are Moderately Associated with the Homeostasis Model Assessment Index of Insulin Resistance in Obese Men
IA Samjoo, A Safdar, MJ Hamadeh, AW Glover, NJ Mocellin, J Santana, JP Little, GR Steinberg, S Raha, MA Tarnopolsky, D Johannsen |
PloS one | 2013 |
|
Doxycycline-Regulated 3T3-L1 Preadipocyte Cell Line with Inducible, Stable Expression of Adenoviral E4orf1 Gene: A Cell Model to Study Insulin-Independent Glucose Disposal
R Krishnapuram, EJ Dhurandhar, O Dubuisson, V Hegde, NV Dhurandhar, M Kanzaki |
PloS one | 2013 |
|
SLE and metabolic syndrome
B Parker, IN Bruce |
Lupus | 2013 |
|
Association of Lifecourse Socioeconomic Status with Chronic Inflammation and Type 2 Diabetes Risk: The Whitehall II Prospective Cohort Study
S Stringhini, GD Batty, P Bovet, MJ Shipley, MG Marmot, M Kumari, AG Tabak, M Kivimäki, RC Ma |
PLoS Medicine | 2013 |
|
Genomic Profiling Reveals That Transient Adipogenic Activation Is a Hallmark of Mouse Models of Skeletal Muscle Regeneration
L Lukjanenko, S Brachat, E Pierrel, E Lach-Trifilieff, JN Feige, F Martelli |
PloS one | 2013 |
|
Lower Maternal Body Condition During Pregnancy Affects Skeletal Muscle Structure and Glut-4 Protein Levels But Not Glucose Tolerance in Mature Adult Sheep
PM Costello, LJ Hollis, RL Cripps, N Bearpark, HP Patel, AA Sayer, C Cooper, MA Hanson, SE Ozanne, LR Green |
Reproductive sciences (Thousand Oaks, Calif.) | 2013 |
|
Two Weeks of Metformin Treatment Enhances Mitochondrial Respiration in Skeletal Muscle of AMPK Kinase Dead but Not Wild Type Mice
JM Kristensen, S Larsen, JW Helge, F Dela, JF Wojtaszewski, M Kanzaki |
PloS one | 2013 |
|
Cigarette smoke exposure severely reduces peripheral insulin sensitivity without changing GLUT4 expression in oxidative muscle of Wistar rats
P Ebersbach-Silva, T Alves, AT Fonseca, MA Oliveira, UF Machado, PM Seraphim |
Arquivos brasileiros de endocrinologia e metabologia | 2013 |
|
Intramyocellular diacylglycerol concentrations and [U- 13 C]palmitate isotopic enrichment measured by LC/MS/MS
AU Blachnio-Zabielska, P Zabielski, MD Jensen |
Journal of lipid research | 2013 |
|
Acute exercise reverses starvation-mediated insulin resistance in humans
P Frank, A Katz, E Andersson, K Sahlin |
American journal of physiology. Endocrinology and metabolism | 2013 |
|
A Systems Biology Approach to Study Metabolic Syndrome
M Orešič, A Vidal-Puig |
2013 | |
|
Sweet Potato [Ipomoea batatas (L.) Lam. ^|^ldquo;Tainong 57^|^rdquo;] Starch Improves Insulin Sensitivity in High-Fructose Diet-Fed Rats by Ameliorating Adipocytokine Levels, Pro-Inflammatory Status, and Insulin Signaling
YY CHEN, MH LAI, HY HUNG, JF LIU |
Journal of Nutritional Science and Vitaminology | 2013 |
|
INSULIN RESISTANCE: GOOD OR BAD? DEVELOPMENT MECHANISMS AND THE ASSOCIATION WITH AGE-RELATED VASCULAR CHANGES
SA Boytsov, ID Strazhesko, DU Akasheva, EN Dudinskaya, AS Kruglikova, ON Tkacheva |
2013 | |
|
The Sphingosine-1-Phosphate Analog FTY720 Reduces Muscle Ceramide Content and Improves Glucose Tolerance in High Fat-Fed Male Mice
CR Bruce, S Risis, JR Babb, C Yang, RS Lee-Young, DC Henstridge, MA Febbraio |
Endocrinology | 2013 |
|
Exercise prescription in the treatment of type 2 diabetes mellitus : current practices, existing guidelines and future directions.
O'Hagan C, De Vito G, Boreham CA |
Sports medicine (Auckland, N.Z.) | 2013 |
|
Novel and reversible mechanisms of smoking-induced insulin resistance in humans
BC Bergman, L Perreault, D Hunerdosse, A Kerege, M Playdon, AM Samek, RH Eckel |
Diabetes | 2012 |
|
Obesity and adipokines: effects on sympathetic overactivity: Adipokines and sympathetic outflow
MM Smith, CT Minson |
The Journal of Physiology | 2012 |
|
Diastolic dysfunction and heart failure with a preserved ejection fraction: Relevance in critical illness and anaesthesia
R Maharaj |
Journal of the Saudi Heart Association | 2012 |
|
Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance
FR Jornayvaz, GI Shulman |
Cell Metabolism | 2012 |
|
Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle
DM Muoio, PD Neufer |
Cell Metabolism | 2012 |
|
Diabetes-Induced Alterations in the Extracellular Matrix and Their Impact on Myocardial Function
B Law, V Fowlkes, JG Goldsmith, W Carver, EC Goldsmith |
Microscopy and Microanalysis | 2012 |
|
Sex-dependent differences in rat brown adipose tissue mitochondrial biogenesis and insulin signaling parameters in response to an obesogenic diet
A Nadal-Casellas, M Bauzá-Thorbrügge, AM Proenza, M Gianotti, I Lladó |
Molecular and Cellular Biochemistry | 2012 |
|
Leptin revisited: its mechanism of action and potential for treating diabetes
R Coppari, C Bjørbæk |
Nature Reviews Drug Discovery | 2012 |
|
Insulin Resistance
AR Sinaiko, S Caprio |
The Journal of Pediatrics | 2012 |
|
Reversal of muscle insulin resistance by weight reduction in young, lean, insulin-resistant offspring of parents with type 2 diabetes
KF Petersen, S Dufour, K Morino, PS Yoo, GW Cline, GI Shulman |
Proceedings of the National Academy of Sciences | 2012 |
|
Toward a unifying hypothesis of metabolic syndrome
AA Bremer, M Mietus-Snyder, RH Lustig |
Pediatrics | 2012 |
|
Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis
C Owen, A Czopek, A Agouni, L Grant, R Judson, EK Lees, GD Mcilroy, O Göransson, A Welch, KK Bence, BB Kahn, BG Neel, N Mody, M Delibegović, ME Saez |
PloS one | 2012 |
|
Loss of toll-like receptor 3 function improves glucose tolerance and reduces liver steatosis in obese mice
LH Wu, CC Huang, S Adhikarakunnathu, LR san Mateo, KE Duffy, P Rafferty, P Bugelski, H Raymond, H Deutsch, K Picha, CK Ward, L Alexoupolou, RA Flavell, ML Mbow, VS Susulic |
Metabolism | 2012 |
|
Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function
AR Martins, RT Nachbar, R Gorjao, MA Vinolo, WT Festuccia, RH Lambertucci, MF Cury-Boaventura, LR Silveira, R Curi, SM Hirabara |
Lipids in Health and Disease | 2012 |
|
Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1
P Ungaro, P Mirra, F Oriente, C Nigro, M Ciccarelli, V Vastolo, M Longo, G Perruolo, R Spinelli, P Formisano, C Miele, F Beguinot |
The Journal of biological chemistry | 2012 |
|
Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation
SM Haldar, D Jeyaraj, P Anand, H Zhu, Y Lu, DA Prosdocimo, B Eapen, D Kawanami, M Okutsu, L Brotto, H Fujioka, J Kerner, MG Rosca, OP McGuinness, RJ Snow, AP Russell, AN Gerber, X Bai, Z Yan, TM Nosek, M Brotto, CL Hoppel, MK Jain |
Proceedings of the National Academy of Sciences | 2012 |
|
Connecting Type 1 and Type 2 Diabetes through Innate Immunity
JI Odegaard, A Chawla |
Cold Spring Harbor Perspectives in Medicine | 2012 |
|
Inflammation and Lipid Signaling in the Etiology of Insulin Resistance
CK Glass, JM Olefsky |
Cell Metabolism | 2012 |
|
Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium
DH Kim, MA Sartor, JR Bain, D Sandoval, RD Stevens, M Medvedovic, CB Newgard, SC Woods, RJ Seeley |
Diabetes | 2012 |
|
Optimized mixture of hops rho iso-alpha acids-rich extract and acacia proanthocyanidins-rich extract reduces insulin resistance in 3T3-L1 adipocytes and improves glucose and insulin control in db/db mice
ML Tripp, G Darland, VR Konda, LM Pacioretty, JL Chang, JS Bland, JG Babish |
Nutrition Research and Practice | 2012 |
|
Role of the PPAR-α agonist fenofibrate in severe pediatric burn
IE Elijah, E Børsheim, DM Maybauer, CC Finnerty, DN Herndon, MO Maybauer |
Burns | 2012 |
|
MicroRNAs in Insulin Resistance and Obesity
MD Williams, GM Mitchell |
Experimental Diabetes Research | 2012 |
|
Mitochondrial inhibitor as a new class of insulin sensitizer
Y Zhang, J Ye |
Acta pharmaceutica Sinica. B | 2012 |
|
Ezetimibe: Its Novel Effects on the Prevention and the Treatment of Cholesterol Gallstones and Nonalcoholic Fatty Liver Disease
O Bari, BA Neuschwander-Tetri, M Liu, P Portincasa, DQ Wang |
Journal of Lipids | 2012 |
|
Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes
K Morino, KF Petersen, S Sono, CS Choi, VT Samuel, A Lin, A Gallo, H Zhao, A Kashiwagi, IJ Goldberg, H Wang, RH Eckel, H Maegawa, GI Shulman |
Diabetes | 2012 |
|
Decreased Transcription of ChREBP- / Isoforms in Abdominal Subcutaneous Adipose Tissue of Obese Adolescents With Prediabetes or Early Type 2 Diabetes: Associations With Insulin Resistance and Hyperglycemia
R Kursawe, S Caprio, C Giannini, D Narayan, A Lin, E D'Adamo, M Shaw, B Pierpont, SW Cushman, GI Shulman |
Diabetes | 2012 |
|
Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β
I Qadri, M Choudhury, SM Rahman, TA Knotts, RC Janssen, J Schaack, M Iwahashi, L Puljak, FR Simon, G Kilic, JG Fitz, JE Friedman |
The Journal of biological chemistry | 2012 |
|
Molecular targets related to inflammation and insulin resistance and potential interventions
SM Hirabara, R Gorjão, MA Vinolo, AC Rodrigues, RT Nachbar, R Curi |
Journal of Biomedicine and Biotechnology | 2012 |
|
Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model
J Xiao, YP Ching, EC Liong, AA Nanji, ML Fung, GL Tipoe |
European Journal of Nutrition | 2012 |
|
Effect of moderate weight loss on hepatic, pancreatic and visceral lipids in obese subjects
AP Rossi, F Fantin, GA Zamboni, G Mazzali, E Zoico, C Bambace, A Antonioli, RP Mucelli, M Zamboni |
Nutrition and Diabetes | 2012 |
|
Depletion of Mitochondrial DNA Stabilizes C1qTNF-Related Protein 6 mRNA in Muscle Cells
MJ Kim, W Lee, EJ Park, SY Park |
Journal of Korean Medical Science | 2012 |
|
A Six-Month Supplementation of Mulberry, Korean Red Ginseng, and Banaba Decreases Biomarkers of Systemic Low-Grade Inflammation in Subjects with Impaired Glucose Tolerance and Type 2 Diabetes
HJ Kim, KH Yoon, MJ Kang, HW Yim, KS Lee, V Vuksan, MK Sung |
Evidence-based complementary and alternative medicine : eCAM | 2012 |
|
Transient Silencing of a Type IV P-Type ATPase, Atp10c, Results in Decreased Glucose Uptake in C2C12 Myotubes
SE Hurst, SC Minkin, J Biggerstaff, MS Dhar |
Journal of nutrition and metabolism | 2012 |
|
Indy Mutants: Live Long and Prosper
S Frankel, B Rogina |
Frontiers in Genetics | 2012 |
|
A Network-Based Approach to Visualize Prevalence and Progression of Metabolic Syndrome Components
R Haring, M Rosvall, U Völker, H Völzke, H Kroemer, M Nauck, H Wallaschofski |
PloS one | 2012 |
|
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity
S Timmers, M Nabben, M Bosma, B Bree, E Lenaers, D Beurden, G Schaart, MS Westerterp-Plantenga, W Langhans, MK Hesselink, VB Schrauwen-Hinderling, P Schrauwen |
Proceedings of the National Academy of Sciences | 2012 |
|
Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects
F Magkos, X Su, D Bradley, E Fabbrini, C Conte, JC Eagon, JE Varela, EM Brunt, BW Patterson, S Klein |
Gastroenterology | 2012 |
|
Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes
SL Hwang, X Li, JY Lee, HW Chang |
Biochemical and Biophysical Research Communications | 2012 |
|
Hypoglycemic and β-cells regenerative effects of Aegle marmelos (L.) Corr. bark extract in streptozotocin-induced diabetic rats
GR Gandhi, S Ignacimuthu, MG Paulraj |
Food and Chemical Toxicology | 2012 |
|
Boissons sucrées et obésité: aspects épidémiologiques et physiopathologiques
KA Lê |
Obésité | 2012 |
|
The mystery of C. elegans aging: An emerging role for fat : Distant parallels between C. elegans aging and metabolic syndrome?
D Ackerman, D Gems |
BioEssays | 2012 |
|
Actions and interactions of AMPK with insulin, the peroxisomal-proliferator activated receptors and sirtuins
MJ Holness, PH Sugden, MF Silvestre, MC Sugden |
Expert Review of Endocrinology & Metabolism | 2012 |
|
Carbon Nanotubes Coupled to siRNA Generates Efficient Transfection and is a Tool for Examining Glucose Uptake in Skeletal Muscle
J Lanner, H Westerblad |
Nanotechnology and Nanomedicine in Diabetes | 2012 |
|
Mechanism of Lipid Induced Insulin Resistance: An Overview
S Bhattacharya, R Kundu, S Dasgupta, S Bhattacharya |
Endocrinology and Metabolism | 2012 |
|
Review: Quantifying Mitochondrial Dysfunction in Complex Diseases of Aging
MP Horan, N Pichaud, JW Ballard |
The Journals of Gerontology Series A Biological Sciences and Medical Sciences | 2012 |
|
Maternal adaptations and inheritance in the transgenerational programming of adult disease
LA Gallo, M Tran, JS Master, KM Moritz, ME Wlodek |
Cell & Tissue Research | 2012 |
|
The Role of the Renin-Angiotensin System in the Development of Insulin Resistance in Skeletal Muscle
EJ Henriksen, M Prasannarong |
Molecular and Cellular Endocrinology | 2012 |
|
Protective potentials of wild rice (Zizania latifolia (Griseb) Turcz) against obesity and lipotoxicity induced by a high-fat/cholesterol diet in rats
SF Han, H Zhang, CK Zhai |
Food and Chemical Toxicology | 2012 |
|
Extended-release niacin with laropiprant : a review on efficacy, clinical effectiveness and safety
R Yadav, M France, N Younis, S Hama, BJ Ammori, S Kwok, H Soran |
Expert Opinion on Pharmacotherapy | 2012 |
|
Muscle
ML Martin, SL Belmonte, R Ram, FA Kamal, BC Blaxall |
Muscle | 2012 |
|
Insights into the role of macrophage migration inhibitory factor in obesity and insulin resistance
OM Finucane, CM Reynolds, FC McGillicuddy, HM Roche |
Proceedings of the Nutrition Society | 2012 |
|
Insulin resistance, metabolic stress, and atherosclerosis
M Pansuria, H Xi, L Li, XF Yang, H Wang |
Frontiers in bioscience (Scholar edition) | 2012 |
|
Association of Hepatitis C Virus With Insulin Resistance: Evidences From Animal Studies and Clinical Studies
S Badar, B Khubaib, M Idrees, A Hussain, Z Awan, S Butt, S Afzal, M Akram, Z Fatima, M Aftab, S Saleem, S Munir, B Rauff, M Naudhani, L Ali, M Ali, I Rehman |
Hepatitis Monthly | 2012 |
|
After Avandia
KI Khalaf, H Taegtmeyer |
Texas Heart Institute Journal | 2012 |
|
Insulin resistance in the brain: An old-age or new-age problem?
R Williamson, A McNeilly, C Sutherland |
Biochemical Pharmacology | 2012 |
|
Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity
S Saenger, B Holtmann, MR Nilges, S Schroeder, A Hoeflich, H Kletzl, W Spooren, S Ostrowitzki, T Hanania, M Sendtner, F Metzger |
Amyotrophic Lateral Sclerosis | 2012 |
|
Islet function in obese adolescents
C Giannini, S Caprio |
Diabetes, Obesity and Metabolism | 2012 |
|
Therapeutic use of recombinant methionyl human leptin
C Vatier, JF Gautier, C Vigouroux |
Biochimie | 2012 |
|
Antihyperglycemic effect of esculetin modulated carbohydrate metabolic enzymes activities in streptozotocin induced diabetic rats
D Prabakaran, N Ashokkumar |
Journal of Functional Foods | 2012 |
|
Insulin resistance: A significant risk factor of endometrial cancer
N Mu, Y Zhu, Y Wang, H Zhang, F Xue |
Gynecologic Oncology | 2012 |
|
GRK5 deficiency decreases diet-induced obesity and adipogenesis
F Wang, L Wang, M Shen, L Ma |
Biochemical and Biophysical Research Communications | 2012 |
|
Adipokines promote lipotoxicity in human skeletal muscle cells
A Taube, S Lambernd, G Echten-Deckert, K Eckardt, J Eckel |
Archives Of Physiology And Biochemistry | 2012 |
|
Increased Bioactive Lipids Content in Human Subcutaneous and Epicardial Fat Tissue Correlates with Insulin Resistance
AU Błachnio-Zabielska, M Baranowski, T Hirnle, P Zabielski, A Lewczuk, I Dmitruk, J Górski |
Lipids | 2012 |
|
Overexpression of AMP-activated protein kinase or Protein Kinase D prevents lipid-induced insulin resistance in cardiomyocytes
LK Steinbusch, E Dirkx, NT Hoebers, V Roelants, M Foretz, B Viollet, M Diamant, G Eys, DM Ouwens, L Bertrand, JF Glatz, JJ Luiken |
Journal of Molecular and Cellular Cardiology | 2012 |
|
Progression of β-Cell Dysfunction in Obese Youth
C Giannini, S Caprio |
Current Diabetes Reports | 2012 |
|
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
HM O’Neill, GP Holloway, GR Steinberg |
Molecular and Cellular Endocrinology | 2012 |
|
Efficacy of 20-OH-ecdysone on hepatic key enzymes of carbohydrate metabolism in streptozotocin induced diabetic rats
R Sundaram, R Naresh, P Shanthi, P Sachdanandam |
Phytomedicine | 2012 |
|
Lipid Sensing and Insulin Resistance in the Brain
JT Yue, TK Lam |
Cell Metabolism | 2012 |
|
Association of Hepatitis C Virus With Insulin Resistance: Evidences From Animal Studies and Clinical Studie
S Badar, B Khubaib, M Idrees, A Hussain, Z Awan, S Butt, S Afzal, M Akram, Z Fatima, M Aftab, S Saleem, S Munir, B Rauff, M Naudhani, L Ali, M Ali, I Rehman |
Hepatitis Monthly | 2012 |
|
PKCθ Expression in the Amygdala Regulates Insulin Signaling, Food Intake and Body Weight
MJ Park-York, S Boghossian, H Oh, DA York |
Obesity | 2012 |
|
Borapetoside C from Tinospora crispa improves insulin sensitivity in diabetic mice
CT Ruan, SH Lam, TC Chi, SS Lee, MJ Su |
Phytomedicine | 2012 |
|
A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle
YC Lai, Y Liu, R Jacobs, MH Rider |
Biochemical Journal | 2012 |
|
Shiftwork and Higher Pancreatic Secretion: Early Detection of an Intermediate State of Insulin Resistance?
Y Esquirol, V Bongard, J Ferrieres, H Verdier, B Perret |
Chronobiology International | 2012 |
|
Macrophage migration inhibitory factor (MIF) enhances palmitic acid- and glucose-induced murine beta cell dysfunction and destruction in vitro
I Stojanovic, T Saksida, G Timotijevic, S Sandler, S Stosic-Grujicic |
Growth Factors | 2012 |
|
α-Glucosidase and α-Amylase Inhibitory Activity of Senna surattensis
E Thilagam, B Parimaladevi, C Kumarappan, SC Mandal |
Journal of Acupuncture and Meridian Studies | 2012 |
|
GRK5 ablation contributes to insulin resistance
L Wang, M Shen, F Wang, L Ma |
Biochemical and Biophysical Research Communications | 2012 |
|
Efficacy of asiatic acid, a pentacyclic triterpene on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats
V Ramachandran, R Saravanan |
Phytomedicine | 2012 |
|
The linkage between inflammation and Type 2 diabetes mellitus
NG Cruz, LP Sousa, MO Sousa, NT Pietrani, AP Fernandes, KB Gomes |
Diabetes Research and Clinical Practice | 2012 |
|
Exercise Prescription in the Treatment of Type 2 Diabetes Mellitus: Current Practices, Existing Guidelines and Future Directions
C O’Hagan, G Vito, CA Boreham |
Sports Medicine | 2012 |
|
Tanshinone IIA improves endoplasmic reticulum stress-induced insulin resistance through AMP-activated protein kinase
SL Hwang, JH Yang, YT Jeong, YD Kim, X Li, Y Lu, YC Chang, KH Son, HW Chang |
Biochemical and Biophysical Research Communications | 2012 |
|
A NEW GALLOYLBERGENIN FROM BERGENIA cRASSIFOLIA WITH ANTI-LIPID DROPLET ACCUMULATION ACTIVITY
H Morita, J Janar, L Fang, CP Wong, T Kaneda, Y Hirasawa, BG Shahmanovna, AZ Abduahitovich |
HETEROCYCLES | 2012 |
|
Characterization of Intra-myocellular Lipids using 2D Localized Correlated Spectroscopy and Abdominal Fat using MRI in Type 2 Diabetes
P Srikanthan, A Singhal, CC Lee, R Nagarajan, N Wilson, CK Roberts, TJ Hahn, MA Thomas |
Magnetic Resonance Insights | 2012 |
|
Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases
HY Suk, C Zhou, TT Yang, H Zhu, RY Yu, O Olabisi, XY Yang, D Brancho, JY Kim, PE Scherer, PG Frank, MP Lisanti, JW Calvert, DJ Lefer, JD Molkentin, A Ghigo, E Hirsch, J Jin, CW Chow |
The Journal of biological chemistry | 2012 |
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Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice
YE Lee, JW Kim, EM Lee, YB Ahn, KH Song, KH Yoon, HW Kim, CW Park, G Li, Z Liu, SH Ko |
PloS one | 2012 |
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Inhibition of p53 attenuates steatosis and liver injury in a mouse model of non-alcoholic fatty liver disease
Z Derdak, KA Villegas, R Harb, AM Wu, A Sousa, JR Wands |
Journal of Hepatology | 2012 |
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The importance of palmitoleic acid to adipocyte insulin resistance and whole-body insulin sensitivity in type 1 diabetes
BC Bergman, D Howard, IE Schauer, DM Maahs, JK Snell-Bergeon, TW Clement, RH Eckel, L Perreault, M Rewers |
The Journal of clinical endocrinology and metabolism | 2012 |
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Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes
KS Kim, DH Oh, JY Kim, BG Lee, JS You, KJ Chang, HJ Chung, MC Yoo, HI Yang, JH Kang, YC Hwang, KJ Ahn, HY Chung, IK Jeong |
Experimental & molecular medicine | 2012 |
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Anti-tumour necrosis factor alpha therapy improves insulin sensitivity in normal-weight but not in obese patients with rheumatoid arthritis
A Stavropoulos-Kalinoglou, GS Metsios, VF Panoulas, P Nightingale, Y Koutedakis, GD Kitas |
Arthritis Research & Therapy | 2012 |
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Activity restriction, impaired capillary function, and the development of insulin resistance in lean primates
SM Chadderdon, JT Belcik, E Smith, L Pranger, P Kievit, KL Grove, JR Lindner |
American journal of physiology. Endocrinology and metabolism | 2012 |
|
The association of ClipR-59 protein with AS160 modulates AS160 protein phosphorylation and adipocyte Glut4 protein membrane translocation
W Ren, S Cheema, K Du |
The Journal of biological chemistry | 2012 |
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Development of associations among central adiposity, adiponectin and insulin sensitivity from adolescence to young adulthood
LJ Rasmussen-Torvik, JS Pankow, DR Jacobs, J Steinberger, A Moran, AR Sinaiko |
Diabetic medicine : a journal of the British Diabetic Association | 2012 |
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A liquid chromatography/tandem mass spectrometry method for measuring the in vivo incorporation of plasma free fatty acids into intramyocellular ceramides in humans
AU Blachnio-Zabielska, XM Persson, C Koutsari, P Zabielski, MD Jensen |
Rapid communications in mass spectrometry : RCM | 2012 |
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Features of hepatic and skeletal muscle insulin resistance unique to type 1 diabetes
BC Bergman, D Howard, IE Schauer, DM Maahs, JK Snell-Bergeon, RH Eckel, L Perreault, M Rewers |
The Journal of clinical endocrinology and metabolism | 2012 |
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Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions
L Abu-Elheiga, H Wu, Z Gu, R Bressler, SJ Wakil |
The Journal of biological chemistry | 2012 |
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Early maternal undernutrition programs increased feed intake, altered glucose metabolism and insulin secretion, and liver function in aged female offspring
LA George, L Zhang, N Tuersunjiang, Y Ma, NM Long, AB Uthlaut, DT Smith, PW Nathanielsz, SP Ford |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2012 |
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Effects of diet and exercise in 337 overweight/obese adults
C Philippou, E Andreou, N Menelaou, P Hajigeorgiou, D Papandreou |
Hippokratia | 2012 |
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RTEF-1 Attenuates Blood Glucose Levels by Regulating Insulin-Like Growth Factor Binding Protein-1 in the Endothelium
AF Messmer-Blust, MJ Philbrick, S Guo, J Wu, P He, S Guo, J Li |
Circulation research | 2012 |
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Acylcarnitines: Reflecting or Inflicting Insulin Resistance?
MG Schooneman, FM Vaz, SM Houten, MR Soeters |
Diabetes | 2012 |
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Chronic Resveratrol Treatment Protects Pancreatic Islets against Oxidative Stress in db/db Mice
YE Lee, JW Kim, EM Lee, YB Ahn, KH Song, KH Yoon, HW Kim, CW Park, G Li, Z Liu, SH Ko, K Maedler |
PloS one | 2012 |
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Bone as a site of insulin resistance in type 2 diabetes
J Wei, G Karsenty |
BMC proceedings | 2012 |
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Aspirin and Blood Glucose and Insulin Resistance
SH Hammadi, SS AL-Ghamdi, AI Yassien, SD AL-Hassani |
Open Journal of Endocrine and Metabolic Diseases | 2012 |
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Changes in protein tyrosine phosphatase activity in Spontaneously Diabetic Torii (SDT) rats
T Yamaguchi, Ohta, H Morinaga, T Hata, E Sato, M Matsushita |
Open Journal of Animal Sciences | 2012 |
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The Carnivore Connection Hypothesis: Revisited
JC Brand-Miller, HJ Griffin, S Colagiuri |
Journal of Obesity | 2012 |
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Liuwei Dihuang Lowers Body Weight and Improves Insulin and Leptin Sensitivity in Obese Rats
B Perry, J Zhang, C Sun, T Saleh, Y Wang |
Evidence-Based Complementary and Alternative Medicine | 2012 |
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The interplay of autoimmunity and insulin resistance in type 1 diabetes
Natalie J Nokoff, Marian Rewers, Melanie Cree Green |
Discovery medicine | 2012 |
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A Network-Based Approach to Visualize Prevalence and Progression of Metabolic Syndrome Components
R Haring, M Rosvall, U Völker, H Völzke, H Kroemer, M Nauck, H Wallaschofski, A Scuteri |
PloS one | 2012 |
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Acetyl-CoA Carboxylase 2 −/− Mutant Mice are Protected against Fatty Liver under High-fat, High-carbohydrate Dietary and de Novo Lipogenic Conditions
L Abu-Elheiga, H Wu, Z Gu, R Bressler, SJ Wakil |
The Journal of biological chemistry | 2012 |
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Peroxisome Proliferator-activated Receptor-γ Activation Enhances Insulin-stimulated Glucose Disposal by Reducing ped/pea-15 Gene Expression in Skeletal Muscle Cells: EVIDENCE FOR INVOLVEMENT OF ACTIVATOR PROTEIN-1
P Ungaro, P Mirra, F Oriente, C Nigro, M Ciccarelli, V Vastolo, M Longo, G Perruolo, R Spinelli, P Formisano, C Miele, F Beguinot |
The Journal of biological chemistry | 2012 |
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Characterization of Intra-myocellular Lipids Using 2d Localized Correlated Spectroscopy and Abdominal Fat Using Mri in Type 2 Diabetes
P Srikanthan, A Singhal, CC Lee, R Nagarajan, N Wilson, CK Roberts, TJ Hahn, MA Thomas |
Magnetic Resonance Insights | 2012 |
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Potential role of insulin signaling on vascular smooth muscle cell migration, proliferation, and inflammation pathways
E Cersosimo, X Xu, N Musi |
American journal of physiology. Cell physiology | 2012 |
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Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice
T Kusakabe, K Ebihara, T Sakai, L Miyamoto, D Aotani, Y Yamamoto, S Yamamoto-Kataoka, M Aizawa-Abe, J Fujikura, K Hosoda, K Nakao |
American journal of physiology. Endocrinology and metabolism | 2012 |
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Determinants of evolving metabolic and cardiovascular benefit/risk profiles of rosiglitazone therapy during the natural history of diabetes: molecular mechanisms in the context of integrated pathophysiology
L Sgarra, F Addabbo, MA Potenza, M Montagnani |
American journal of physiology. Endocrinology and metabolism | 2012 |
|
Early maternal undernutrition programs increased feed intake, altered glucose metabolism and insulin secretion, and liver function in aged female offspring
LA George, L Zhang, N Tuersunjiang, Y Ma, NM Long, AB Uthlaut, DT Smith, PW Nathanielsz, SP Ford |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2012 |
|
Activity restriction, impaired capillary function, and the development of insulin resistance in lean primates
SM Chadderdon, JT Belcik, E Smith, L Pranger, P Kievit, KL Grove, JR Lindner |
American journal of physiology. Endocrinology and metabolism | 2012 |
|
Levels of Free Fatty Acids (FFA) Are Associated with Insulin Resistance But Do Not Explain the Relationship between Adiposity and Insulin Resistance in Hispanic Americans: The IRAS Family Study
MR Miller, RI Pereira, CD Langefeld, C Lorenzo, JI Rotter, YD Chen, RN Bergman, LE Wagenknecht, JM Norris, TE Fingerlin |
The Journal of clinical endocrinology and metabolism | 2012 |
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The first luminal loop confers insulin responsiveness to glucose transporter 4
JY Kim, KV Kandror, J Chernoff |
Molecular biology of the cell | 2012 |
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Animal Models in Diabetes Research
HG Joost, H Al-Hasani, A Schürmann |
2012 | |
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Mitochondria and Their Role in Cardiovascular Disease
J Marín-García |
2012 | |
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Diabetes: An Old Disease, a New Insight
SI Ahmad |
2012 | |
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Diabetes mellitus and other pathology in patients with INS and INSR mutations
YA Pankov |
Diabetes mellitus | 2012 |
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High levels of dietary fat impair glucose homeostasis in rainbow trout
AC Figueiredo-Silva, S Panserat, S Kaushik, I Geurden, S Polakof |
The Journal of experimental biology | 2012 |
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Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPARα/PGC1α and thermogenic glycerolipid/fatty acid cycling
JE Rame, LA Barouch, MN Sack, EG Lynn, M Abu-Asab, M Tsokos, SJ Kern, JJ Barb, PJ Munson, MK Halushka, KL Miller, K Fox-Talbot, J Zhang, JM Hare, MA Solomon, RL Danner |
Physiological genomics | 2011 |
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Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice*
MJ Jurczak, AH Lee, FR Jornayvaz, HY Lee, AL Birkenfeld, BA Guigni, M Kahn, VT Samuel, LH Glimcher, GI Shulman |
The Journal of biological chemistry | 2011 |
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Glucose-lowering effect of DLBS3233 is mediated through phosphorylation of tyrosine and upregulation of PPARγ and GLUT4 expression
OM Tandrasasmita, DD Wulan, F Nailufar, J Sinambela, RR Tjandrawinata |
International journal of general medicine | 2011 |
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Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
N Kumashiro, DM Erion, D Zhang, M Kahn, SA Beddow, X Chu, CD Still, GS Gerhard, X Han, J Dziura, KF Petersen, VT Samuel, GI Shulman |
Proceedings of the National Academy of Sciences | 2011 |
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Magnetic Resonance Spectroscopy Studies of Human Metabolism
DE Befroy, GI Shulman |
Diabetes | 2011 |
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Pathophysiology of insulin resistance and steatosis in patients with chronic viral hepatitis
M Basaranoglu, G Basaranoglu |
World journal of gastroenterology : WJG | 2011 |
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Acute Disruption of Leptin Signaling in Vivo Leads to Increased Insulin Levels and Insulin Resistance
J Levi, SL Gray, M Speck, FK Huynh, SL Babich, WT Gibson, TJ Kieffer |
Endocrinology | 2011 |
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Metabolic syndrome as a risk factor for neurological disorders
AA Farooqui, T Farooqui, F Panza, V Frisardi |
Cellular and Molecular Life Sciences | 2011 |
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The macrophage at the intersection of immunity and metabolism in obesity
MC Samaan |
Diabetology & metabolic syndrome | 2011 |
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Immunomodulation at epithelial sites by obesity and metabolic disease
KP Cheung, KR Taylor, JM Jameson |
Immunologic Research | 2011 |
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Macrophage-mediated inflammation in metabolic disease
A Chawla, KD Nguyen, YP Goh |
Nature reviews. Immunology | 2011 |
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Sirtuin-1 regulation of mammalian metabolism
MP Gillum, DM Erion, GI Shulman |
Trends in Molecular Medicine | 2011 |
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Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders
CS Kim, JG Kim, BJ Lee, MS Choi, HS Choi, T Kawada, KU Lee, R Yu |
Diabetes | 2011 |
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SirT1 Regulates Adipose Tissue Inflammation
MP Gillum, ME Kotas, DM Erion, R Kursawe, P Chatterjee, KT Nead, ES Muise, JJ Hsiao, DW Frederick, S Yonemitsu, AS Banks, L Qiang, S Bhanot, JM Olefsky, DD Sears, S Caprio, GI Shulman |
Diabetes | 2011 |
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Impact of CD1d Deficiency on Metabolism
ME Kotas, HY Lee, MP Gillum, C Annicelli, BA Guigni, GI Shulman, R Medzhitov |
PloS one | 2011 |
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Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance
A Luria, A Bettaieb, Y Xi, GJ Shieh, HC Liu, H Inoue, HJ Tsai, JD Imig, FG Haj, BD Hammock |
Proceedings of the National Academy of Sciences | 2011 |
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Energy substrate partitioning and efficiency in individuals with atherogenic lipoprotein phenotype
N Faghihnia, PW Siri-Tarino, RM Krauss, GA Brooks |
Obesity (Silver Spring, Md.) | 2011 |
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Remodeling lipid metabolism and improving insulin responsiveness in human primary myotubes
LM Sparks, C Moro, B Ukropcova, S Bajpeyi, AE Civitarese, MW Hulver, GH Thoresen, AC Rustan, SR Smith |
PloS one | 2011 |
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Type 2 Diabetes Mellitus: A Possible Surgically Reversible Intestinal Dysfunction
PC Sala, RS Torrinhas, SB Heymsfield, DL Waitzberg |
Obesity Surgery | 2011 |
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Acute high-fat feeding does not prevent the improvement in glucose tolerance after resistance exercise in lean individuals
CS Shaw, NM Cooper, O Shaw, P Salomao, AJ Wagenmakers |
European Journal of Applied Physiology | 2011 |
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Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain
SA Paranjape, O Chan, W Zhu, AM Horblitt, CA Grillo, S Wilson, L Reagan, RS Sherwin |
American journal of physiology. Endocrinology and metabolism | 2011 |
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Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2
FR Jornayvaz, AL Birkenfeld, MJ Jurczak, S Kanda, BA Guigni, DC Jiang, D Zhang, HY Lee, VT Samuel, GI Shulman |
Proceedings of the National Academy of Sciences | 2011 |
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Bioactives from bitter melon enhance insulin signaling and modulate acyl carnitine content in skeletal muscle in high-fat diet-fed mice
ZQ Wang, XH Zhang, Y Yu, A Poulev, D Ribnicky, ZE Floyd, WT Cefalu |
The Journal of Nutritional Biochemistry | 2011 |
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Apelin and insulin resistance: Another arrow for the quiver?
S Xu, PS Tsao, P Yue |
Journal of Diabetes | 2011 |
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Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats
V Melenovsky, J Benes, P Skaroupkova, D Sedmera, H Strnad, M Kolar, C Vlcek, J Petrak, J Benes, F Papousek, O Oliyarnyk, L Kazdova, L Cervenka |
Molecular and Cellular Biochemistry | 2011 |
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Skeletal Muscle Mitochondrial Capacity and Insulin Resistance in Type 2 Diabetes
S Bajpeyi, M Pasarica, C Moro, K Conley, S Jubrias, O Sereda, DH Burk, Z Zhang, A Gupta, L Kjems, SR Smith |
The Journal of clinical endocrinology and metabolism | 2011 |
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Deletion of the Mammalian INDY Homologue Mimics Aspects of Dietary Restriction and Protects Against Adiposity and Insulin Resistance in Mice
AL Birkenfeld, HY Lee, F Guebre-Egziabher, TC Alves, MJ Jurczak, FR Jornayvaz, D Zhang, JJ Hsiao, A Martin-Montalvo, A Fischer-Rosinsky, J Spranger, AF Pfeiffer, J Jordan, MF Fromm, J König, S Lieske, CM Carmean, DW Frederick, D Weismann, F Knauf, PM Irusta, RD Cabo, SL Helfand, VT Samuel, GI Shulman |
Cell Metabolism | 2011 |
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Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance
FR Jornayvaz, HY Lee, MJ Jurczak, TC Alves, F Guebre-Egziabher, BA Guigni, D Zhang, VT Samuel, JE Silva, GI Shulman |
Endocrinology | 2011 |
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Natural vanadium-containing Jeju ground water stimulates glucose uptake through the activation of AMP-activated protein kinase in L6 myotubes.
Hwang SL, Chang HW |
Molecular and Cellular Biochemistry | 2011 |
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Metabolic Syndrome
M Wang |
Metabolic Syndrome | 2011 |
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Oxidative Stress and Disease
I Paur, M Carlsen, B Halvorsen, R Blomhoff |
Herbal Medicine | 2011 |
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The Metabolic Syndrome
S Devaraj, D Siegel, I Jialal |
The Metabolic Syndrome | 2011 |
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Insulin Resistance: Pathophysiology and Rationale for Treatment
S Muntoni, S Muntoni |
Annals of Nutrition and Metabolism | 2011 |
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AMP-activated protein kinase modulators: a patent review (2006 – 2010)
H Yun, J Ha |
Expert Opinion on Therapeutic Patents | 2011 |
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Progress in Molecular Biology and Translational Science
JF Wilkins, F Úbeda |
Modifications of Nuclear DNA and its Regulatory Proteins | 2011 |
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Obesity, blood vessels and metabolic syndrome
M Tesauro, C Cardillo |
Acta Physiologica | 2011 |
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Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15
VC Tuei, JS Ha, CE Ha |
Life Sciences | 2011 |
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1H NMR-Based Metabonomic Analysis of Metabolic Changes of Serum and Liver in Zucker Obese Rats
L Zhao, X Zhang, H Wang, D Lin |
Analytical Letters | 2011 |
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Metabolic flexibility and obesity in children and youth
J Aucouturier, P Duché, BW Timmons |
Obesity Reviews | 2011 |
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Unsaturated fatty acids repress the expression of ATP-binding cassette transporter A1 in HepG2 and FHs 74 Int cells
CS Ku, HE Rasmussen, Y Park, ED Jesch, J Lee |
Nutrition Research | 2011 |
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Antidiabetic Activities of Abutilon indicum (L.) Sweet Are Mediated by Enhancement of Adipocyte Differentiation and Activation of the GLUT1 Promoter
C Krisanapun, SH Lee, P Peungvicha, R Temsiririrkkul, SJ Baek |
Evidence-based complementary and alternative medicine : eCAM | 2011 |
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Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement
ME Weinberg, MC Roman, P Jacob, M Wen, P Cheung, UA Walker, K Mulligan, M Schambelan |
PloS one | 2011 |
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Obesity-associated insulin resistance in skeletal muscle: Role of lipid accumulation and physical inactivity
K Eckardt, A Taube, J Eckel |
Reviews in Endocrine and Metabolic Disorders | 2011 |
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Physiopathologie de l’insulinorésistance dans le muscle squelettique et implication des fonctions mitochondriales
V Barquissau, B Morio |
Nutrition Clinique et Métabolisme | 2011 |
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Insulin effects in muscle and adipose tissue
G Dimitriadis, P Mitrou, V Lambadiari, E Maratou, SA Raptis |
Diabetes Research and Clinical Practice | 2011 |
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Interaction between maternal obesity and post-natal over-nutrition on skeletal muscle metabolism
D Simar, H Chen, K Lambert, J Mercier, MJ Morris |
Nutrition, Metabolism and Cardiovascular Diseases | 2011 |
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Skeletal muscle fat content is inversely associated with bone strength in young girls
JN Farr, JL Funk, Z Chen, JR Lisse, RM Blew, VR Lee, M Laudermilk, TG Lohman, SB Going |
Journal of Bone and Mineral Research | 2011 |
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Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo
K Mai, J Andres, T Bobbert, A Assmann, K Biedasek, S Diederich, I Graham, TR Larson, AF Pfeiffer, J Spranger |
Metabolism | 2011 |
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Dietary Saury Oil Reduces Hyperglycemia and Hyperlipidemia in Diabetic KKAy Mice and in Diet-Induced Obese C57BL/6J Mice by Altering Gene Expression
ZH Yang, H Miyahara, S Takemura, A Hatanaka |
Lipids | 2011 |
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DLBS3233 increases glucose uptake by mediating upregulation of PPARγ and PPARδ expression
F Nailufar, OM Tandrasasmita, RR Tjandrawinata |
Biomedicine & Preventive Nutrition | 2011 |
|
Complicaciones metabólicas de la obesidad infantil
D Yeste, A Carrascosa |
Anales de Pediatría | 2011 |
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Different roles of zinc plus arachidonic acid on insulin sensitivity between high fructose- and high fat-fed rats
I Hwang, T Yoon, C Kim, B Cho, S Lee, MK Song |
Life Sciences | 2011 |
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A higher-carbohydrate, lower-fat diet reduces fasting glucose concentration and improves β-cell function in individuals with impaired fasting glucose
BA Gower, LL Goree, PC Chandler-Laney, AC Ellis, K Casazza, WM Granger |
Metabolism | 2011 |
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PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders
S Saenger, C Goeldner, JR Frey, L Ozmen, S Ostrowitzki, W Spooren, TM Ballard, E Prinssen, E Borroni, F Metzger |
Growth Hormone & IGF Research | 2011 |
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Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease
S Zaitone, N Hassan, N El-Orabi, ES El-Awady |
European Journal of Pharmacology | 2011 |
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Waist circumference and metabolic risk factors have separate and additive effects on the risk of future Type 2 diabetes in patients with vascular diseases. A cohort study
AM Wassink, Y der Graaf, TW van Haeften, W Spiering, SS Soedamah-Muthu, FL Visseren |
Diabetic Medicine | 2011 |
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Sarcopenia and Obesity
DL Waters, RN Baumgartner |
Clinics in Geriatric Medicine | 2011 |
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Irbesartan Prevents Metabolic Syndrome in Rats via Activation of Peroxisome Proliferator-Activated Receptor γ
S Takai, D Jin, M Miyazaki |
Journal of Pharmacological Sciences | 2011 |
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Transcriptional co-factors and hepatic energy metabolism
A Sommerfeld, A Krones-Herzig, S Herzig |
Molecular and Cellular Endocrinology | 2011 |
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The Sugar Is sIRVed: Sorting Glut4 and Its Fellow Travelers
KV Kandror, PF Pilch |
Traffic | 2011 |
|
The safety of thiazolidinediones
KG Tolman |
Expert Opinion on Drug Safety | 2011 |
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Anti-diabetic effects of mildronate alone or in combination with metformin in obese Zucker rats
E Liepinsh, E Skapare, B Svalbe, M Makrecka, H Cirule, M Dambrova |
European Journal of Pharmacology | 2011 |
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Physiopathological Mechanism of Sarcopenia
S Walrand, C Guillet, J Salles, N Cano, Y Boirie |
Clinics in Geriatric Medicine | 2011 |
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Accuracy, Reproducibility and Repeatability of Ultrasonography in the Assessment of Abdominal Adiposity
A Bazzocchi, G Filonzi, F Ponti, C Sassi, E Salizzoni, G Battista, R Canini |
Academic Radiology | 2011 |
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Increased Lipid Accumulation in Liver and White Adipose Tissue in Aging in the SAMP10 Mouse
T HONMA, M YANAKA, T TSUDUKI, I IKEDA |
Journal of Nutritional Science and Vitaminology | 2011 |
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Hepatitis C Virus Infection: Molecular Pathways to Insulin resistance
F Parvaiz, S Manzoor, H Tariq, F Javed, K Fatima, I Qadri |
Virology Journal | 2011 |
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Natural vanadium-containing Jeju ground water stimulates glucose uptake through the activation of AMP-activated protein kinase in L6 myotubes
SL Hwang, HW Chang |
Molecular and Cellular Biochemistry | 2011 |
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The difficult diabetic: Part 2
AK Cook |
Companion Animal | 2011 |
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HIV protease inhibitors induce metabolic dysfunction in part via increased JNK1/2 pro-inflammatory signaling in L6 cells
LD Bogachus, LP Turcotte |
Antiviral Research | 2011 |
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Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee |
Annual Reports in Medicinal Chemistry Volume 46 | 2011 |
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Caenorhabditis elegans ucp-4 regulates fat metabolism: Suppression of ucp-4 expression induced obese phenotype and caused impairment of insulin like pathway
C Ji, W Guo, M Zhang, X Lu, Y Ni, X Guo |
Gene | 2011 |
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Progressive Hyperglycemia across the Glucose Tolerance Continuum in Older Obese Adults Is Related to Skeletal Muscle Capillarization and Nitric Oxide Bioavailability
TP Solomon, JM Haus, Y Li, JP Kirwan |
The Journal of clinical endocrinology and metabolism | 2011 |
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Activation of AMP-Activated Protein Kinase Prevents Lipotoxicity in Retinal Pericytes
JM Cacicedo, S Benjachareonwong, E Chou, N Yagihashi, NB Ruderman, Y Ido |
Investigative ophthalmology & visual science | 2011 |
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Sexually Dimorphic Diet-Induced Insulin Resistance in Obese Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)-Deficient Mice
DM Jaworski, O Sideleva, HM Stradecki, GD Langlois, A Habibovic, B Satish, WG Tharp, J Lausier, K Larock, TL Jetton, M Peshavaria, RE Pratley |
Endocrinology | 2011 |
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Effects of ethinyl estradiol and desogestrel on clinical and metabolic parameters in Indian patients with polycystic ovary syndrome : Desogestrel pill
SM Bhattacharya, M Ghosh, R Basu |
Journal of Obstetrics and Gynaecology Research | 2011 |
|
Diabetes and Insulin Resistance in Pediatric Obesity
G Kim, S Caprio |
Pediatric Clinics of North America | 2011 |
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Effect of iridoid glucoside on streptozotocin induced diabetic rats and its role in regulating carbohydrate metabolic enzymes
R Sundaram, R Naresh, R Ranadevan, P Shanthi, P Sachdanandam |
European Journal of Pharmacology | 2011 |
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Not only accumulation, but also saturation status of intramuscular lipids is significantly affected by PPARγ activation : PPARγ activation and lipid saturation status
A Chabowski, M Żendzian-Piotrowska, A Nawrocki, J Górski |
Acta Physiologica | 2011 |
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Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice
N Yamagishi, T Ueda, A Mori, Y Saito, T Hatayama |
Biochemical and Biophysical Research Communications | 2011 |
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Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase
KD Freeman-Cook, P Amor, SJ Bader, LM Buzon, SB Coffey, J Corbett, K Dirico, SD Doran, RL Elliott, W Esler, A Guzman-Perez, KE Henegar, JA Houser, CS Jones, C Limberakis, K Loomis, K McPherson, S Murdande, K Nelson, D Phillion, B Pierce, W Song, E Sugarman, S Tapley, M Tu, Z Zhao |
Journal of Medicinal Chemistry | 2011 |
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Effects of an Intervention and Maintenance Weight Loss Diet with and without Exercise on Anthropometric Indices in Overweight and Obese Healthy Women
E Andreou, C Philippou, D Papandreou |
Annals of Nutrition and Metabolism | 2011 |
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Serum chitotriosidase activity: is it a new inflammatory marker in obese children?
AA Kundak, ME Tascılar, A Abaci, I Devrim, IT Ozgen, U Demirtek, O Ozturk, A Olgun, I Kurt |
Journal of Pediatric Endocrinology and Metabolism | 2011 |
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Antidiabetic effect of total saponins from Entada phaseoloides (L.) Merr. in type 2 diabetic rats
T Zheng, G Shu, Z Yang, S Mo, Y Zhao, Z Mei |
Journal of Ethnopharmacology | 2011 |
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Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages
CS Ku, Y Park, SL Coleman, J Lee |
The Journal of Nutritional Biochemistry | 2011 |
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Myostatin as a Potential Therapeutic Target for Obesity and Insulin Resistance
KH Jeong, CS Choi |
The Korean Journal of Obesity | 2011 |
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Effect of Diabetes on Alteration of Metabolism in Cardiac Myocytes: Therapeutic Implications
SK Kota, SK Kota, S Jammula, M Pharm, S Panda, KD Modi |
Diabetes Technology & Therapeutics | 2011 |
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Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling
H Song, M Wohltmann, M Tan, S Bao, JH Ladenson, J Turk |
The Journal of biological chemistry | 2011 |
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Equine Hyperlipidemias
HC McKenzie |
Veterinary Clinics of North America: Equine Practice | 2011 |
|
Circulating Brain-Derived Neurotrophic Factor Concentration Is Downregulated by Intralipid/Heparin Infusion or High-Fat Meal in Young Healthy Male Subjects
M Karczewska-Kupczewska, I Kowalska, A Nikolajuk, A Adamska, M Zielinska, N Kaminska, E Otziomek, M Gorska, M Strczkowski |
Diabetes care | 2011 |
|
Type 2 Diabetes in Youth: Epidemiology and Pathophysiology
E D'Adamo, S Caprio |
Diabetes care | 2011 |
|
Is There a Metabolic Program in the Skeletal Muscle of Obese Individuals?
JA Houmard, WJ Pories, GL Dohm |
Journal of Obesity | 2011 |
|
A Chinese Herbal Decoction, Dang Gui Bu Xue Tang, Prepared from Radix Astragali and Radix Angelicae sinensis , Ameliorates Insulin Resistance Induced by A High-Fructose Diet in Rats
IM Liu, TF Tzeng, SS Liou |
Evidence-Based Complementary and Alternative Medicine | 2011 |
|
Impact of CD1d Deficiency on Metabolism
ME Kotas, HY Lee, MP Gillum, C Annicelli, BA Guigni, GI Shulman, R Medzhitov, S Jeyaseelan |
PloS one | 2011 |
|
Enhanced Uridine Bioavailability Following Administration of a Triacetyluridine-Rich Nutritional Supplement
ME Weinberg, MC Roman, P Jacob, M Wen, P Cheung, UA Walker, K Mulligan, M Schambelan, WL Zhou |
PloS one | 2011 |
|
O exercício físico melhora a sensibilidade à insulina de ratos expostos à fumaça de cigarro
PE Silva, T Alves, ÁT Fonseca, MA Oliveira, UF Machado, PM Seraphim |
Revista Brasileira de História | 2011 |
|
Group VIA PLA 2 (iPLA 2 β) Is Activated Upstream of p38 Mitogen-activated Protein Kinase (MAPK) in Pancreatic Islet β-Cell Signaling
H Song, M Wohltmann, M Tan, S Bao, JH Ladenson, J Turk |
The Journal of biological chemistry | 2011 |
|
Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice
MJ Jurczak, AH Lee, FR Jornayvaz, HY Lee, AL Birkenfeld, BA Guigni, M Kahn, VT Samuel, LH Glimcher, GI Shulman |
The Journal of biological chemistry | 2011 |
|
Caloric restriction in leptin deficiency does not correct myocardial steatosis: failure to normalize PPARα/PGC1α and thermogenic glycerolipid/fatty acid cycling
JE Rame, LA Barouch, MN Sack, EG Lynn, M Abu-Asab, M Tsokos, SJ Kern, JJ Barb, PJ Munson, MK Halushka, KL Miller, K Fox-Talbot, J Zhang, JM Hare, MA Solomon, RL Danner |
Physiological genomics | 2011 |
|
Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain
SA Paranjape, O Chan, W Zhu, AM Horblitt, CA Grillo, S Wilson, L Reagan, RS Sherwin |
American journal of physiology. Endocrinology and metabolism | 2011 |
|
Proinflammatory gene expression and renal lipogenesis are modulated by dietary protein content in obese Zucker fa / fa rats
C Tovar-Palacio, AR Tovar, N Torres, C Cruz, R Hernández-Pando, G Salas-Garrido, J Pedraza-Chaverri, R Correa-Rotter |
American journal of physiology. Renal physiology | 2011 |
|
Obesity in the pathogenesis of type 2 diabetes
C Day, CJ Bailey |
The British Journal of Diabetes & Vascular Disease | 2011 |
|
Atlas of Diabetes
J Skyler |
2011 | |
|
Subacute Endotoxemia Induces Adipose Inflammation and Changes in Lipid and Lipoprotein Metabolism in Cats
M Osto, E Zini, M Franchini, C Wolfrum, F Guscetti, M Hafner, M Ackermann, CE Reusch, TA Lutz |
Endocrinology | 2011 |
|
Three Weeks on a High-Fat Diet Increases Intrahepatic Lipid Accumulation and Decreases Metabolic Flexibility in Healthy Overweight Men
NA van Herpen, VB Schrauwen-Hinderling, G Schaart, RP Mensink, P Schrauwen |
The Journal of clinical endocrinology and metabolism | 2011 |
|
Dietary saury oil reduces hyperglycemia and hyperlipidemia in diabetic KKAy mice and in diet-induced obese C57BL/6J mice by altering gene expression.
Yang ZH, Miyahara H, Takemura S, Hatanaka A |
Lipids | 2011 |
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Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism
A Kumar, JC Lawrence, DY Jung, HJ Ko, SR Keller, JK Kim, MA Magnuson, TE Harris |
Diabetes | 2010 |
|
Lipid-induced insulin resistance: unravelling the mechanism
VT Samuel, KF Petersen, GI Shulman |
Lancet | 2010 |
|
Inflammation and insulin resistance: an old story with new ideas
JK Kim |
Korean Diabetes Journal | 2010 |
|
The Role of Muscle Insulin Resistance in the Pathogenesis of Atherogenic Dyslipidemia and Nonalcoholic Fatty Liver Disease Associated with the Metabolic Syndrome
FR Jornayvaz, VT Samuel, GI Shulman |
Annual Review of Nutrition | 2010 |
|
Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain
AM Hennige, M Heni, J Machann, H Staiger, T Sartorius, M Hoene, R Lehmann, C Weigert, A Peter, A Bornemann, S Kroeber, A Pujol, S Franckhauser, F Bosch, F Schick, R Lammers, HU Häring |
Journal of Cellular and Molecular Medicine | 2010 |
|
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
RR Ricardo-Gonzalez, AR Eagle, JI Odegaard, H Jouihan, CR Morel, JE Heredia, L Mukundan, D Wu, RM Locksley, A Chawla |
Proceedings of the National Academy of Sciences | 2010 |
|
Skeletal muscle insulin resistance: the interplay of local lipid excess and mitochondrial dysfunction
L Chow, A From, E Seaquist |
Metabolism: clinical and experimental | 2010 |
|
Berberine reduces endoplasmic reticulum stress and improves insulin signal transduction in Hep G2 cells
Z Wang, F Lu, L Xu, H Dong |
Acta Pharmacologica Sinica | 2010 |
|
Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis
H Kaneto, N Katakami, M Matsuhisa, T Matsuoka |
Mediators of Inflammation | 2010 |
|
Molecular mechanisms of insulin resistance in type 2 diabetes mellitus
V Saini |
World journal of diabetes | 2010 |
|
Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance
HY Lee, CS Choi, AL Birkenfeld, TC Alves, FR Jornayvaz, MJ Jurczak, D Zhang, DK Woo, GS Shadel, W Ladiges, PS Rabinovitch, JH Santos, KF Petersen, VT Samuel, GI Shulman |
Cell Metabolism | 2010 |
|
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
S Cipriani, A Mencarelli, G Palladino, S Fiorucci |
Journal of lipid research | 2010 |
|
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen |
2010 | |
|
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen |
2010 | |
|
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen |
2010 | |
|
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen |
2010 | |
|
Knockdown of the gene encoding Drosophila tribbles homologue 3 (Trib3) improves insulin sensitivity through peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in a rat model of insulin resistance
D Weismann, DM Erion, I Ignatova-Todorava, Y Nagai, R Stark, JJ Hsiao, C Flannery, AL Birkenfeld, T May, M Kahn, D Zhang, XX Yu, SF Murray, S Bhanot, BP Monia, GW Cline, GI Shulman, VT Samuel |
Diabetologia | 2010 |
|
Effects of rosiglitazone on intramyocellular lipid accumulation in Psammomys obesus
JC Molero, S Lee, I Leizerman, A Chajut, A Cooper, K Walder |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2010 |
|
Deletion of the -Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity
WA Chutkow, AL Birkenfeld, JD Brown, HY Lee, DW Frederick, J Yoshioka, P Patwari, R Kursawe, SW Cushman, J Plutzky, GI Shulman, VT Samuel, RT Lee |
Diabetes | 2010 |
|
Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis[S]
L Jia, Y Ma, S Rong, JL Betters, P Xie, S Chung, N Wang, W Tang, L Yu |
Journal of lipid research | 2010 |
|
Palmitate Attenuates Insulin Signaling and Induces Endoplasmic Reticulum Stress and Apoptosis in Hypothalamic Neurons: Rescue of Resistance and Apoptosis through Adenosine 5′ Monophosphate-Activated Protein Kinase Activation
CM Mayer, DD Belsham |
Endocrinology | 2010 |
|
Fatty acids increase glucose uptake and metabolism in C2C12 myoblasts stably transfected with human lipoprotein lipase
WH Capell, IR Schlaepfer, P Wolfe, PA Watson, DH Bessesen, MJ Pagliassotti, RH Eckel |
American journal of physiology. Endocrinology and metabolism | 2010 |
|
Cyclooxygenase 2 Inhibition Exacerbates Palmitate-Induced Inflammation and Insulin Resistance in Skeletal Muscle Cells
T Coll, X Palomer, F Blanco-Vaca, JC Escolà-Gil, RM Sánchez, JC Laguna, M Vázquez-Carrera |
Endocrinology | 2010 |
|
Glycerol-3-phosphate acyltransferase 1 deficiency in ob/ob mice diminishes hepatic steatosis but does not protect against insulin resistance or obesity
AA Wendel, LO Li, Y Li, GW Cline, GI Shulman, RA Coleman |
Diabetes | 2010 |
|
Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
JR Ussher, TR Koves, VJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, DG Lopaschuk, SD Proctor, W Keung, DM Muoio, GD Lopaschuk |
Diabetes | 2010 |
|
Exposure to bioaccumulative organochlorine compounds alters adipogenesis, fatty acid uptake, and adipokine production in NIH3T3-L1 cells
GH 3rd, L Mangum |
Toxicology in vitro : an international journal published in association with BIBRA | 2010 |
|
Neuronal regulation of homeostasis by nutrient sensing
TK Lam |
Nature Medicine | 2010 |
|
From the Cover: Feature Article: Leptin therapy in insulin-deficient type I diabetes
M Wang, L Chen, GO Clark, Y Lee, RD Stevens, OR Ilkayeva, BR Wenner, JR Bain, MJ Charron, CB Newgard, RH Unger |
Proceedings of the National Academy of Sciences | 2010 |
|
Peroxisome Proliferator-activated Receptor α Is Responsible for the Up-regulation of Hepatic Glucose-6-phosphatase Gene Expression in Fasting and db/db Mice*
SS Im, MY Kim, SK Kwon, TH Kim, JS Bae, H Kim, KS Kim, GT Oh, YH Ahn |
The Journal of biological chemistry | 2010 |
|
Brown adipose tissue—a new role in humans?
ME Lidell, S Enerbäck |
Nature Reviews Endocrinology | 2010 |
|
Regulation of mitochondrial biogenesis
FR Jornayvaz, GI Shulman |
Essays in Biochemistry | 2010 |
|
Regional Anatomic Differences in Skeletal Muscle Mitochondrial Respiration in Type 2 Diabetes and Obesity
R Rabøl, S Larsen, PM Højberg, T Almdal, R Boushel, SB Haugaard, JL Andersen, S Madsbad, F Dela |
The Journal of clinical endocrinology and metabolism | 2010 |
|
Relationship of Intramyocellular Lipid to Insulin Sensitivity May Differ With Ethnicity in Healthy Girls and Women
JC Lawrence, BR Newcomer, SD Buchthal, B Sirikul, RA Oster, GR Hunter, BA Gower |
Obesity (Silver Spring, Md.) | 2010 |
|
Insulin resistance is not conserved in myotubes established from women with PCOS
M Eriksen, AD Pørneki, V Skov, JS Burns, H Beck-Nielsen, D Glintborg, M Gaster |
PloS one | 2010 |
|
Acyl-CoA synthesis, lipid metabolism and lipotoxicity
LO Li, EL Klett, RA Coleman |
Biochimica et Biophysica Acta | 2010 |
|
Burger's Medicinal Chemistry and Drug Discovery
S Bruno, L Ronda, S Faggiano, S Bettati, A Mozzarelli |
Burger's Medicinal Chemistry and Drug Discovery | 2010 |
|
Textbook of Diabetes
PM Jones, SJ Persaud |
Textbook of Diabetes | 2010 |
|
Fatty acids inhibit insulin-mediated glucose transport associated with actin remodeling in rat L6 muscle cells
HL Zhao, LZ Liu, Y Sui, SK Ho, SK Tam, FM Lai, JC Chan, PC Tong |
Acta Diabetologica | 2010 |
|
Loss of insulin-mediated microvascular perfusion in skeletal muscle is associated with the development of insulin resistance
P St-Pierre, AJ Genders, MA Keske, SM Richards, S Rattigan |
Diabetes, Obesity and Metabolism | 2010 |
|
Differential aetiology and impact of phosphoinositide 3-kinase (PI3K) and Akt signalling in skeletal muscle on in vivo insulin action
M Friedrichsen, P Poulsen, EA Richter, BF Hansen, JB Birk, R Ribel-Madsen, K Stender-Petersen, E Nilsson, H Beck-Nielsen, A Vaag, JF Wojtaszewski |
Diabetologia | 2010 |
|
Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet
NE Sunny, S Satapati, X Fu, TT He, R Mehdibeigi, C Spring-Robinson, J Duarte, MJ Potthoff, JD Browning, SC Burgess |
American journal of physiology. Endocrinology and metabolism | 2010 |
|
Pharmacological profiles of a novel protein tyrosine phosphatase 1B inhibitor, JTT-551
S Fukuda, T Ohta, S Sakata, H Morinaga, M Ito, Y Nakagawa, M Tanaka, M Matsushita |
Diabetes, Obesity and Metabolism | 2010 |
|
Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes
A Zelezniak, TH Pers, S Soares, ME Patti, KR Patil |
PLoS computational biology | 2010 |
|
Regulation of skeletal muscle mitochondrial function: genes to proteins
IR Lanza, KS Nair |
Acta physiologica (Oxford, England) | 2010 |
|
Metabolic syndrome and cardiovascular risk
AM Alshehri |
Journal of family and community medicine | 2010 |
|
Exercise training improves cardiovascular autonomic modulation in response to glucose ingestion in obese adults with and without type 2 diabetes mellitus
S Goulopoulou, T Baynard, RM Franklin, B Fernhall, R Carhart, R Weinstock, JA Kanaley |
Metabolism: clinical and experimental | 2010 |
|
Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice
M He, H Su, W Gao, SM Johansson, Q Liu, X Wu, J Liao, AA Young, T Bartfai, MW Wang |
PloS one | 2010 |
|
Insulin, leptin and reward
JF Davis, DL Choi, SC Benoit |
Trends in endocrinology and metabolism: TEM | 2010 |
|
Obesity in the elderly: is faulty metabolism to blame?
DL Johannsen, E Ravussin |
Aging Health | 2010 |
|
Increased prevalence of the metabolic syndrome in patients with psoriatic arthritis
SK Raychaudhuri, S Chatterjee, C Nguyen, M Kaur, I Jialal, SP Raychaudhuri |
Metabolic Syndrome and Related Disorders | 2010 |
|
Caloric restriction with or without exercise: the fitness versus fatness debate
DE Larson-Meyer, L Redman, LK Heilbronn, CK Martin, E Ravussin |
Medicine and science in sports and exercise | 2010 |
|
Hepatic PTP1B Deficiency: The Promise of a Treatment for Metabolic Syndrome?
KK Bence |
Journal of clinical metabolism & diabetes | 2010 |
|
Glycaemic control in type 2 diabetes: Targets and new therapies
AA Tahrani, MK Piya, A Kennedy, AH Barnett |
Pharmacology & Therapeutics | 2010 |
|
Adiponectin Is Inversely Associated With Intramyocellular and Intrahepatic Lipids in Obese Premenopausal Women
MA Bredella, M Torriani, RH Ghomi, BJ Thomas, DJ Brick, AV Gerweck, LM Harrington, KK Miller |
Obesity | 2010 |
|
Comparison of 3.0 T proton magnetic resonance spectroscopy short and long echo-time measures of intramyocellular lipids in obese and normal-weight women
MA Bredella, RH Ghomi, BJ Thomas, KK Miller, M Torriani |
Journal of Magnetic Resonance Imaging | 2010 |
|
Intrahepatic and intramyocellular lipids are determinants of insulin resistance in prepubertal children
DE Larson-Meyer, BR Newcomer, E Ravussin, J Volaufova, B Bennett, S Chalew, WT Cefalu, M Sothern |
Diabetologia | 2010 |
|
The Effect of Exercise and Nutrition on Intramuscular Fat Metabolism and Insulin Sensitivity
CS Shaw, J Clark, AJ Wagenmakers |
Annual Review of Nutrition | 2010 |
|
Interaction of the hepatitis C virus (HCV) core with cellular genes in the development of HCV-induced steatosis
M Khan, S Jahan, S Khaliq, B Ijaz, W Ahmad, B Samreen, S Hassan |
Archives of Virology | 2010 |
|
Insulin resistance at the crossroads of metabolic syndrome: Systemic analysis using microarrays
E Kim |
Biotechnology Journal | 2010 |
|
Stearoyl-CoA desaturase and insulin signaling — What is the molecular switch?
P Dobrzyn, M Jazurek, A Dobrzyn |
Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2010 |
|
Allosteric Regulation of Glycogen Synthase Controls Glycogen Synthesis in Muscle
M Bouskila, RW Hunter, AF Ibrahim, L Delattre, M Peggie, JA van Diepen, PJ Voshol, J Jensen, K Sakamoto |
Cell Metabolism | 2010 |
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Ascofuranone prevents ER stress-induced insulin resistance via activation of AMP-activated protein kinase in L6 myotube cells
SL Hwang, HW Chang, IK Lee, BK Yang, J Magae, YC Chang |
Biochemical and Biophysical Research Communications | 2010 |
|
Pregnancy and lactation have anti-obesity and anti-diabetic effects inAy/amice
EN Makarova, TV Yakovleva, AY Shevchenko, NM Bazhan |
Acta Physiologica | 2010 |
|
Recruitment of brown fat and conversion of white into brown adipocytes: Strategies to fight the metabolic complications of obesity?
D Langin |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2010 |
|
Subclinical Metabolic Abnormalities Associated with Obesity in Prepubertal Mexican Schoolchildren
JB Romero, E Briones, GC Palacios, K Castelán |
Journal of Pediatric Endocrinology and Metabolism | 2010 |
|
Combination peroxisome proliferator-activated receptor γ and α agonist treatment in Type 2 diabetes prevents the beneficial pioglitazone effect on liver fat content
R Balasubramanian, J Gerrard, CD Man, MJ Firbank, A Lane, PT English, C Cobelli, R Taylor |
Diabetic Medicine | 2010 |
|
Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes
AR Cameron, S Anil, E Sutherland, J Harthill, G Rena |
Metallomics | 2010 |
|
Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells
SM Hirabara, R Curi, P Maechler |
Journal of Cellular Physiology | 2010 |
|
Inhibitory effect on protein kinase Cθ by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes
L Yang, Z Qian, H Ji, R Yang, Y Wang, L Xi, L Sheng, B Zhao, X Zhang |
European Journal of Pharmacology | 2010 |
|
The Metabolic Syndrome in Systemic Lupus Erythematosus
B Parker, IN Bruce |
Rheumatic Disease Clinics of North America | 2010 |
|
Insulin-resistance and benign prostatic hyperplasia: The connection
A Vikram, G Jena, P Ramarao |
European Journal of Pharmacology | 2010 |
|
Inhibition of protein tyrosine phosphatase 1B and regulation of insulin signalling markers by caffeoyl derivatives of chicory ( Cichorium intybus) salad leaves
VS Muthusamy, C Saravanababu, M Ramanathan, RB Raja, S Sudhagar, S Anand, BS Lakshmi |
British Journal of Nutrition | 2010 |
|
Antidiabetic Effect and Mechanism of Chitooligosaccharides
C Ju, W Yue, Z Yang, Q Zhang, X Yang, Z Liu, F Zhang |
Biological & Pharmaceutical Bulletin | 2010 |
|
Evaluation of insulin-induced GLUT4 vesicle transport and insulin resistance
T Imamura |
Folia Pharmacologica Japonica | 2010 |
|
Meta-analysis: insulin sensitizers for the treatment of non-alcoholic steatohepatitis
MO Rakoski, AG Singal, MA Rogers, H Conjeevaram |
Alimentary Pharmacology & Therapeutics | 2010 |
|
Equine Metabolic Syndrome
N Frank, RJ Geor, SR Bailey, AE Durham, PJ Johnson |
Journal of Veterinary Internal Medicine | 2010 |
|
Association of CD36 gene variants rs1761667 (G>A) and rs1527483 (C>T) with Type 2 diabetes in North Indian population
M Banerjee, S Gautam, M Saxena, HK Bid, CG Agrawal |
International Journal of Diabetes Mellitus | 2010 |
|
The effect of mosapride (5HT-4 receptor agonist) on insulin sensitivity and GLUT4 translocation
JS Nam, JY Nam, JS Yoo, M Cho, JS Park, CW Ahn, BS Cha, EJ Lee, SK Lim, KR Kim, HC Lee |
Diabetes Research and Clinical Practice | 2010 |
|
Metabolic profiling of muscle contraction in lean compared with obese rodents
JP Thyfault, MG Cree, EB Tapscott, JA Bell, TR Koves, O Ilkayeva, RR Wolfe, GL Dohm, DM Muoio |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2010 |
|
Relationship between Insulin Sensitivity and Muscle Lipids may Differ with Muscle Group and Ethnicity
JC Lawrence, BA Gower, WT Garvey, AJ Muñoz, BE Darnell, RA Oster, SD Buchthal, MI Goran, BR Newcomer |
The Open Obesity Journal | 2010 |
|
Protein Misfolding Diseases: Current and Emerging Principles and Therapies
JD Malhotra, RJ Kaufman |
Protein Misfolding Diseases: Current and Emerging Principles and Therapies | 2010 |
|
Obesity Prevention
J Blundell, E Bryant, C Lawton, J Halford, E Naslund, G Finlayson, N King |
Obesity Prevention | 2010 |
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Generation, validation and humanisation of a novel insulin resistant cell model
L Logie, AJ Ruiz-Alcaraz, CJ Schofield, HS Hundal, GZ Feuerstein, JD Brady, D Crowther, AM Tommasi, CE Grierson, B Shepherd, AD Morris, MK Hansen, E Pearson, C Sutherland |
Biochemical Pharmacology | 2010 |
|
Tous les acides gras saturés ont-ils le même effet métabolique ?
S Walrand, F Fisch, JM Bourre |
Nutrition Clinique et Métabolisme | 2010 |
|
Cellularity and Adipogenic Profile of the Abdominal Subcutaneous Adipose Tissue From Obese Adolescents: Association With Insulin Resistance and Hepatic Steatosis
R Kursawe, M Eszlinger, D Narayan, T Liu, M Bazuine, AM Cali, E D'Adamo, M Shaw, B Pierpont, GI Shulman, SW Cushman, A Sherman, S Caprio |
Diabetes | 2010 |
|
Thiazolinedione treatment in PCOS – an update
D Glintborg, M Andersen |
Gynecological Endocrinology | 2010 |
|
Reversal of Obesity and Insulin Resistance by a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist in Diet-Induced Obese Mice
M He, H Su, W Gao, SM Johansson, Q Liu, X Wu, J Liao, AA Young, T Bartfai, MW Wang, K Maedler |
PloS one | 2010 |
|
Metabolic Network Topology Reveals Transcriptional Regulatory Signatures of Type 2 Diabetes
A Zelezniak, TH Pers, S Soares, ME Patti, KR Patil, CA Ouzounis |
PLoS computational biology | 2010 |
|
Insulin Resistance Is Not Conserved in Myotubes Established from Women with PCOS
M Eriksen, AD Pørneki, V Skov, JS Burns, H Beck-Nielsen, D Glintborg, M Gaster, K Stadler |
PloS one | 2010 |
|
Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis
L Jia, Y Ma, S Rong, JL Betters, P Xie, S Chung, N Wang, W Tang, L Yu |
Journal of lipid research | 2010 |
|
Peroxisome Proliferator-activated Receptor α Is Responsible for the Up-regulation of Hepatic Glucose-6-phosphatase Gene Expression in Fasting and db/db Mice
SS Im, MY Kim, SK Kwon, TH Kim, JS Bae, H Kim, KS Kim, GT Oh, YH Ahn |
The Journal of biological chemistry | 2010 |
|
Visceral Adiposity, Insulin Resistance, and Type 2 Diabetes
ML Griffith, LM Younk, SN Davis |
American journal of lifestyle medicine | 2010 |
|
Molecular mechanisms of insulin resistance in type 2 diabetes mellitus
V Saini |
World journal of diabetes | 2010 |
|
Metabolic profiling of muscle contraction in lean compared with obese rodents
JP Thyfault, MG Cree, EB Tapscott, JA Bell, TR Koves, O Ilkayeva, RR Wolfe, GL Dohm, DM Muoio |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2010 |
|
Metabolic Effects of Fructose and the Worldwide Increase in Obesity
L Tappy, KA Lê |
Physiological reviews | 2010 |
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Myocardial Fatty Acid Metabolism in Health and Disease
GD Lopaschuk, JR Ussher, CD Folmes, JS Jaswal, WC Stanley |
Physiological reviews | 2010 |
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Insulin-sensitive obesity
N Klöting, M Fasshauer, A Dietrich, P Kovacs, MR Schön, M Kern, M Stumvoll, M Blüher |
American journal of physiology. Endocrinology and metabolism | 2010 |
|
Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet
NE Sunny, S Satapati, X Fu, TT He, R Mehdibeigi, C Spring-Robinson, J Duarte, MJ Potthoff, JD Browning, SC Burgess |
American journal of physiology. Endocrinology and metabolism | 2010 |
|
Fatty acids increase glucose uptake and metabolism in C 2 C 12 myoblasts stably transfected with human lipoprotein lipase
WH Capell, IR Schlaepfer, P Wolfe, PA Watson, DH Bessesen, MJ Pagliassotti, RH Eckel |
American journal of physiology. Endocrinology and metabolism | 2010 |
|
Diet-induced obesity obstructs insulin signaling in the heart
LH Young |
American journal of physiology. Heart and circulatory physiology | 2010 |
|
Atlas of Atherosclerosis and Metabolic Syndrome
SM Grundy |
2010 | |
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Reduced Respiratory Capacity in Muscle Mitochondria of Obese Subjects
L Bakkman, M Fernström, P Loogna, O Rooyackers, L Brandt, YT Lagerros |
Obesity facts | 2010 |
|
Novel Insights into Adipose Cell Functions
Y Christen, K Clément, BM Spiegelman |
2010 | |
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Urinary Tract Stone Disease
NP Rao, GM Preminger, JP Kavanagh |
2010 | |
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The role of nonesterified fatty acids in pathogenesis of cardiovascular diseases
MV Tsvetkova, VN Khirmanov, NN Zybina |
2010 | |
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Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians.
Bian L, Hanson RL, Muller YL, Ma L, Kobes S, Knowler WC, Bogardus C, Baier LJ |
Diabetologia | 2010 |
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Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice
T Fujimoto, K Miyasaka, M Koyanagi, T Tsunoda, I Baba, K Doi, M Ohta, N Kato, T Sasazuki, S Shirasawa |
PloS one | 2009 |
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Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
EG Hong, HJ Ko, YR Cho, HJ Kim, Z Ma, TY Yu, RH Friedline, E Kurt-Jones, R Finberg, MA Fischer, EL Granger, CC Norbury, SD Hauschka, WM Philbrick, CG Lee, JA Elias, JK Kim |
Diabetes | 2009 |
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Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
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Molecular mechanisms involved in NAFLD progression
M Malaguarnera, MD Rosa, F Nicoletti, L Malaguarnera |
Journal of Molecular Medicine | 2009 |
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Novel methods for measuring cardiac autophagy in vivo
CN Perry, S Kyoi, N Hariharan, H Takagi, J Sadoshima, RA Gottlieb |
Methods in enzymology | 2009 |
|
Diabetische Herzinsuffizienz
M Resl, M Hülsmann, R Pacher, M Clodi |
Wiener Medizinische Wochenschrift | 2009 |
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Lipid induced overexpression of NF-κB in skeletal muscle cells is linked to insulin resistance
P Barma, S Bhattacharya, A Bhattacharya, R Kundu, S Dasgupta, A Biswas, S Bhattacharya, SS Roy, S Bhattacharya |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2009 |
|
Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1
L Liu, X Shi, CS Choi, GI Shulman, K Klaus, KS Nair, GJ Schwartz, Y Zhang, IJ Goldberg, YH Yu |
Diabetes | 2009 |
|
Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction
SA Cook, A Varela-Carver, M Mongillo, C Kleinert, MT Khan, L Leccisotti, N Strickland, T Matsui, S Das, A Rosenzweig, P Punjabi, PG Camici |
European Heart Journal | 2009 |
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Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase
JR Ussher, TR Koves, JS Jaswal, L Zhang, O Ilkayeva, JR Dyck, DM Muoio, GD Lopaschuk |
Diabetes | 2009 |
|
Beneficial effects of leptin on glycaemic and lipid control in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and a high-fat diet
T Kusakabe, H Tanioka, K Ebihara, M Hirata, L Miyamoto, F Miyanaga, H Hige, D Aotani, T Fujisawa, H Masuzaki, K Hosoda, K Nakao |
Diabetologia | 2009 |
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Oleic acid inhibits hepatic insulin signaling through deregulation of STAT3 activation and C/EBPα expression
KJ Kim, HY Kim, EJ Son, J Heo, JH Cheong |
Cellular Signalling | 2009 |
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Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
R Rabøl, PF Svendsen, M Skovbro, R Boushel, SB Haugaard, P Schjerling, P Schrauwen, MK Hesselink, L Nilas, S Madsbad, F Dela |
Metabolism | 2009 |
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Mitochondrial dysfunction and lipotoxicity
P Schrauwen, V Schrauwen-Hinderling, J Hoeks, MK Hesselink |
Biochimica et Biophysica Acta | 2009 |
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Mouse models of inherited lipodystrophy
DB Savage |
Disease models & mechanisms | 2009 |
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Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
E Fabbrini, F Magkos, BS Mohammed, T Pietka, NA Abumrad, BW Patterson, A Okunade, S Klein |
Proceedings of the National Academy of Sciences | 2009 |
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Exercise therapy in type 2 diabetes
SF Praet, LJ van Loon |
Acta Diabetologica | 2009 |
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Ethnic differences in hepatic steatosis: An insulin resistance paradox?
R Guerrero, GL Vega, SM Grundy, JD Browning |
Hepatology | 2009 |
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Pathogenesis and Pathophysiology of the Cardiometabolic Syndrome
EP Kirk, S Klein |
The Journal of Clinical Hypertension | 2009 |
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PANDER binds to the liver cell membrane and inhibits insulin signaling in HepG2 cells
J Yang, C Wang, J Li, BR Burkhardt, CE Robert-Cooperman, C Wilson, Z Gao, BA Wolf |
FEBS Letters | 2009 |
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Lipogenesis in arterial wall and vascular smooth muscular cells: regulation and abnormalities in insulin-resistance
N Hamlat, F Forcheron, S Negazzi, P del Carmine, P Feugier, G Bricca, S Aouichat-Bouguerra, M Beylot |
Cardiovascular Diabetology | 2009 |
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Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells
A Arellano-Plancarte, J Hernandez-Aranda, KJ Catt, JA Olivares-Reyes |
Biochemical Pharmacology | 2009 |
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Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization
F Capel, E Klimcáková, N Viguerie, B Roussel, M Vítková, M Kováciková, J Polák, Z Kovácová, J Galitzky, JJ Maoret, J Hanácek, TH Pers, A Bouloumié, V Stich, D Langin |
Diabetes | 2009 |
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Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling
PC Kienesberger, D Lee, T Pulinilkunnil, DS Brenner, L Cai, C Magnes, HC Koefeler, IE Streith, GN Rechberger, G Haemmerle, JS Flier, R Zechner, YB Kim, EE Kershaw |
The Journal of biological chemistry | 2009 |
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Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
Y Zhang, S Goldman, R Baerga, Y Zhao, M Komatsu, S Jin |
Proceedings of the National Academy of Sciences | 2009 |
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Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition
LO Li, JM Ellis, HA Paich, S Wang, N Gong, G Altshuller, RJ Thresher, TR Koves, SM Watkins, DM Muoio, GW Cline, GI Shulman, RA Coleman |
The Journal of biological chemistry | 2009 |
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Insulin resistance due to lipid-induced signaling defects could be prevented by mahanine
A Biswas, S Bhattacharya, S Dasgupta, R Kundu, SS Roy, BC Pal, S Bhattacharya |
Molecular and Cellular Biochemistry | 2009 |
|
Diabetes and apoptosis: lipotoxicity
CM Kusminski, S Shetty, L Orci, RH Unger, PE Scherer |
Apoptosis | 2009 |
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Impact of treating the metabolic syndrome on chronic kidney disease
V Agrawal, A Shah, C Rice, BA Franklin, PA McCullough |
Nature Reviews Nephrology | 2009 |
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Medium-chain fatty acids ameliorate insulin resistance caused by high-fat diets in rats
S Wein, S Wolffram, J Schrezenmeir, D Gašperiková, I Klimeš, E Šeböková |
Diabetes/Metabolism Research and Reviews | 2009 |
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A cukorbetegség és a diasztolés szívelégtelenség kapcsolata, valamint az echokardiográfia diagnosztikus szerepe
A Nagy, Z Cserép |
Orvosi Hetilap | 2009 |
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Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass
V Delghingaro-Augusto, CJ Nolan, D Gupta, TL Jetton, MG Latour, M Peshavaria, SR Madiraju, É Joly, ML Peyot, M Prentki, J Leahy |
Diabetologia | 2009 |
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Effects of Zinc Plus Arachidonic Acid on Insulin Resistance in High Fructose-Fed Rats
CS Choi, YW Kim, HS Lee, TH Yoon, BM Cho, SI Lee, SS Kim, IK Hwang |
Journal of the Korean Society of Food Science and Nutrition | 2009 |
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Reduction of renal triglyceride accumulation: effects on proximal tubule Na+/H+ exchange and urinary acidification
IA Bobulescu, M Dubree, J Zhang, P McLeroy, OW Moe |
American journal of physiology. Renal physiology | 2009 |
|
Angiotensin II and the development of insulin resistance: Implications for diabetes
JA Olivares-Reyes, A Arellano-Plancarte, JR Castillo-Hernandez |
Molecular and Cellular Endocrinology | 2009 |
|
Changes of glycogen content in liver, skeletal muscle, and heart from fasted rats
E Kokubun, SM Hirabara, J Fiamoncini, R Curi, H Haebisch |
Cell Biochemistry and Function | 2009 |
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Oleate protects against palmitate-induced insulin resistance in L6 myotubes
D Gao, HR Griffiths, CJ Bailey |
British Journal of Nutrition | 2009 |
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Role of ectopic fat in the pathogenesis of insulin resistance
K Kantartzis, C Totsikas, HU Häring, N Stefan |
Clinical Lipidology | 2009 |
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Effects of insulin resistance on endothelial progenitor cells and vascular repair
RM Cubbon, MB Kahn, SB Wheatcroft |
Clinical Science | 2009 |
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Intramyocellular lipid levels are associated with peripheral, but not hepatic, insulin sensitivity in normal healthy subjects
B Salgin, AJ Sleigh, RM Williams, SJ Jackson, LJ Bluck, PR Murgatroyd, SM Humphreys, S Harding, TA Carpenter, DB Dunger |
Clinical Science | 2009 |
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Potential mechanisms of muscle mitochondrial dysfunction in aging and obesity and cellular consequences
E Chanséaume, B Morio |
International journal of molecular sciences | 2009 |
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Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice
H Zong, CC Bastie, J Xu, R Fassler, KP Campbell, IJ Kurland, JE Pessin |
The Journal of biological chemistry | 2009 |
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Metabolic effects of low glycaemic index diets
G Radulian, E Rusu, A Dragomir, M Posea |
Nutrition Journal | 2009 |
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Loss of protein kinase Cbeta function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance
W Huang, R Bansode, M Mehta, KD Mehta |
Hepatology | 2009 |
|
Fatty acids, insulin resistance, and protein metabolism
SC Kalhan |
The Journal of clinical endocrinology and metabolism | 2009 |
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Nonalcoholic fatty liver disease as a comorbidity of childhood obesity
NJ Barshop, CS Francis, JB Schwimmer, JE Lavine |
Pediatric Health | 2009 |
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Advantages of dynamic "closed loop" stable isotope flux phenotyping over static "open loop" clamps in detecting silent genetic and dietary phenotypes
B Vaitheesvaran, FY Chueh, J Xu, C Trujillo, MF Saad, WN Lee, OP McGuinness, IJ Kurland |
Metabolomics : Official journal of the Metabolomic Society | 2009 |
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Oxidant stress-induced loss of IRS-1 and IRS-2 proteins in rat skeletal muscle: role of p38 MAPK
TL Archuleta, AM Lemieux, V Saengsirisuwan, MK Teachey, KA Lindborg, JS Kim, EJ Henriksen |
Free radical biology & medicine | 2009 |
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C1q tumor necrosis factor alpha-related protein isoform 5 is increased in mitochondrial DNA-depleted myocytes and activates AMP-activated protein kinase
SY Park, JH Choi, HS Ryu, YK Pak, KS Park, HK Lee, W Lee |
The Journal of biological chemistry | 2009 |
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Glucose dysregulation and hepatic steatosis in obese adolescents: is there a link?
AM Cali, AM de Oliveira, H Kim, S Chen, M Reyes-Mugica, S Escalera, J Dziura, SE Taksali, R Kursawe, M Shaw, M Savoye, B Pierpont, RT Constable, S Caprio |
Hepatology | 2009 |
|
Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes
C Zhang, MS Yoon, J Chen |
American journal of physiology. Endocrinology and metabolism | 2009 |
|
Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance
MC Allemand, BA Irving, YW Asmann, KA Klaus, L Tatpati, CC Coddington, KS Nair |
PloS one | 2009 |
|
Dietary interventions for metabolic syndrome: role of modifying dietary fats
CL Kien |
Current Diabetes Reports | 2009 |
|
Carnitine and type 2 diabetes
RL Mynatt |
Diabetes/Metabolism Research and Reviews | 2009 |
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Fyn kinase function in lipid utilization: a new upstream regulator of AMPK activity?
M Vatish, E Yamada, JE Pessin, CC Bastie |
Archives Of Physiology And Biochemistry | 2009 |
|
Central Administration of an Endoplasmic Reticulum Stress Inducer Inhibits the Anorexigenic Effects of Leptin and Insulin
JC Won, PG Jang, C Namkoong, EH Koh, SK Kim, JY Park, KU Lee, MS Kim |
Obesity | 2009 |
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Management of cardiovascular disease risk in chronic inflammatory disorders
MJ Kaplan |
Nature Reviews Rheumatology | 2009 |
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Effects of curcuminoid supplement on cardiac autonomic status in high-fat–induced obese rats
A Pongchaidecha, N Lailerd, W Boonprasert, N Chattipakorn |
Nutrition | 2009 |
|
Short-term fatty acid effects on adipocyte glucose uptake: Mechanistic insights
M Haag, AC Malipa, DH Papendorp, PI Stivaktas, S Alummoottil, AM Koorts |
Prostaglandins, Leukotrienes and Essential Fatty Acids | 2009 |
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Potential Therapeutic Strategies for Fat Induced Insulin Resistance
CS Choi |
Journal of Korean Endocrine Society | 2009 |
|
Mechanisms involved in cholesterol-induced neuronal insulin resistance
C Taghibiglou, CA Bradley, T Gaertner, Y Li, Y Wang, YT Wang |
Neuropharmacology | 2009 |
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Diabetes and apoptosis: liver
JM Schattenberg, M Schuchmann |
Apoptosis | 2009 |
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Peroxisome proliferator-activated receptor-α activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats
SJ Shin, JH Lim, S Chung, DY Youn, HW Chung, HW Kim, JH Lee, YS Chang, CW Park |
Hypertension Research | 2009 |
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Insulin glulisine: preclinical hallmarks and clinical efficacy
F Schliess, T Heise |
Therapy | 2009 |
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Effects of coronary artery disease and percutaneous intervention on the cardiac metabolism of nonesterified fatty acids and insulin: Implications of diabetes mellitus
RJ Jaumdally, GY Lip, JV Patel, RJ MacFadyen, C Varma |
Journal of Internal Medicine | 2009 |
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Exercise training reduces circulating adiponectin levels in patients with chronic heart failure
AM Van Berendoncks, P Beckers, VY Hoymans, N Possemiers, FL Wuyts, CJ Vrints, VM Conraads |
Clinical Science | 2009 |
|
Diabetische Herzinsuffizienz
M Resl, M Hülsmann, R Pacher, M Clodi |
focus neurogeriatrie | 2009 |
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Glycaemic load is associated with insulin resistance in older Australian women
TA O'Sullivan, AP Bremner, S O'Neill, P Lyons-Wall |
European Journal of Clinical Nutrition | 2009 |
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Adipocyte fatty acid binding protein during refeeding of female patients with anorexia nervosa
J Engl, A Tschoner, M Willis, I Schuster, S Kaser, M Laimer, W Biebl, JR Patsch, B Mangweth, CF Ebenbichler |
European Journal of Nutrition | 2009 |
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Sarcolemmal fatty acid uptake vs. mitochondrial β-oxidation as target to regress cardiac insulin resistanceThis paper is one of a selection of papers published in this Special Issue, entitled 14th International Biochemistry of Exercise Conference – Muscles as Molecular and Metabolic Machines, and has undergone the Journal’s usual peer review process
JJ Luiken |
Applied Physiology, Nutrition, and Metabolism | 2009 |
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Improvement of high-fat-diet-induced metabolic syndrome by a compound from Balanophora polyandra Griff in mice
R Tao, F Ye, Y He, J Tian, G Liu, T Ji, Y Su |
European Journal of Pharmacology | 2009 |
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Adipophilin distribution and colocalisation with lipid droplets in skeletal muscle
CS Shaw, M Sherlock, PM Stewart, AJ Wagenmakers |
Histochemistry and Cell Biology | 2009 |
|
Cellular glucose transport and glucotransporter 4 expression as a therapeutic target: clinical and experimental studies
A Czech, P Piątkiewicz, J Tatoń |
Archivum Immunologiae et Therapiae Experimentalis | 2009 |
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Functional proteomic analysis of nonalcoholic fatty liver disease in rat models: Enoyl-coenzyme a hydratase down-regulation exacerbates hepatic steatosis
X Zhang, J Yang, Y Guo, H Ye, C Yu, C Xu, L Xu, S Wu, W Sun, H Wei, X Gao, Y Zhu, X Qian, Y Jiang, Y Li, F He |
Hepatology | 2009 |
|
Abelmoschus moschatus(Malvaceae), an aromatic plant, suitable for medical or food uses to improve insulin sensitivity
IM Liu, TF Tzeng, SS Liou |
Phytotherapy Research | 2009 |
|
Effects of endotoxaemia and carbohydrate overload on glucose and insulin dynamics and the development of laminitis in horses
F Tóth, N Frank, KA Chameroy, RC Boston |
Equine Veterinary Journal | 2009 |
|
Overexpression of liver-specific cytochrome P4502E1 impairs hepatic insulin signaling in a transgenic mouse model of nonalcoholic fatty liver disease
E Kathirvel, K Morgan, SW French, TR Morgan |
European Journal of Gastroenterology & Hepatology | 2009 |
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The Transcription Factor TFAP2B Is Associated With Insulin Resistance and Adiposity in Healthy Adolescents
N Nordquist, C Göktürk, E Comasco, D Eensoo, L Merenäkk, T Veidebaum, L Oreland, J Harro |
Obesity | 2009 |
|
Effects of visceral fat accumulation in obesity and type 2 diabetes
G Fatati, E Mirri, S Coaccioli |
Mediterranean Journal of Nutrition and Metabolism | 2009 |
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Rapid down-regulation of mitochondrial fat metabolism in human muscle after training cessation is dissociated from changes in insulin sensitivity
V Rimbert, H Vidal, P Duché, C Debard, C Giraudet, Y Boirie, JM Chardigny, B Morio |
FEBS Letters | 2009 |
|
Efficacy of coumarin on hepatic key enzymes of glucose metabolism in chemical induced type 2 diabetic rats
L Pari, N Rajarajeswari |
Chemico-Biological Interactions | 2009 |
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Antidiabetic effects of Artemisia sphaerocephala Krasch. gum, a novel food additive in China, on streptozotocin-induced type 2 diabetic rats
XH Xing, ZM Zhang, XZ Hu, RQ Wu, C Xu |
Journal of Ethnopharmacology | 2009 |
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Are girls more insulin-resistant than boys?
V Hirschler, G Maccallini, C Karam, C Gonzalez, C Aranda |
Clinical Biochemistry | 2009 |
|
Hepatic insulin resistance, metabolic syndrome and cardiovascular disease
R Meshkani, K Adeli |
Clinical Biochemistry | 2009 |
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Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus
X Li, Z Xu, X Lu, X Yang, P Yin, H Kong, Y Yu, G Xu |
Analytica Chimica Acta | 2009 |
|
High-fat diet induced adiposity and insulin resistance in mice lacking the myotonic dystrophy protein kinase
E Llagostera, MC Carmona, M Vicente, RM Escorihuela, P Kaliman |
FEBS Letters | 2009 |
|
Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease
WQ Zhao, M Townsend |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2009 |
|
Effect of Testosterone on Insulin Stimulated IRS1 Ser Phosphorylation in Primary Rat Myotubes—A Potential Model for PCOS-Related Insulin Resistance
MC Allemand, BA Irving, YW Asmann, KA Klaus, L Tatpati, CC Coddington, KS Nair, C Zhang |
PloS one | 2009 |
|
Decrease in leptin production by the adipose tissue in obesity associated with severe metabolic syndrome
GJ da Paz-Filho, A Volaco, HL Suplicy, RB Radominski, CL Boguszewski |
Arquivos brasileiros de endocrinologia e metabologia | 2009 |
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Liver-specific Loss of Long Chain Acyl-CoA Synthetase-1 Decreases Triacylglycerol Synthesis and β-Oxidation and Alters Phospholipid Fatty Acid Composition
LO Li, JM Ellis, HA Paich, S Wang, N Gong, G Altshuller, RJ Thresher, TR Koves, SM Watkins, DM Muoio, GW Cline, GI Shulman, RA Coleman |
The Journal of biological chemistry | 2009 |
|
C1q Tumor Necrosis Factor α-related Protein Isoform 5 Is Increased in Mitochondrial DNA-depleted Myocytes and Activates AMP-activated Protein Kinase
SY Park, JH Choi, HS Ryu, YK Pak, KS Park, HK Lee, W Lee |
The Journal of biological chemistry | 2009 |
|
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker ( fa / fa ) obese rats
S Cipriani, A Mencarelli, G Palladino, S Fiorucci |
Journal of lipid research | 2009 |
|
Getting the message across: mechanisms of physiological cross talk by adipose tissue
DE Lee, S Kehlenbrink, H Lee, M Hawkins, JS Yudkin |
American journal of physiology. Endocrinology and metabolism | 2009 |
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APPL1: role in adiponectin signaling and beyond
SS Deepa, LQ Dong |
American journal of physiology. Endocrinology and metabolism | 2009 |
|
Role of the atypical protein kinase Cζ in regulation of 5′-AMP-activated protein kinase in cardiac and skeletal muscle
JR Ussher, JS Jaswal, CS Wagg, HE Armstrong, DG Lopaschuk, W Keung, GD Lopaschuk |
American journal of physiology. Endocrinology and metabolism | 2009 |
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Palmitate- and lipopolysaccharide-activated macrophages evoke contrasting insulin responses in muscle cells
V Samokhvalov, PJ Bilan, JD Schertzer, CN Antonescu, A Klip |
American journal of physiology. Endocrinology and metabolism | 2009 |
|
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
KA Posey, DJ Clegg, RL Printz, J Byun, GJ Morton, A Vivekanandan-Giri, S Pennathur, DG Baskin, JW Heinecke, SC Woods, MW Schwartz, KD Niswender |
American journal of physiology. Endocrinology and metabolism | 2009 |
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Role of lipid-derived mediators in skeletal muscle insulin resistance
A Taube, K Eckardt, J Eckel |
American journal of physiology. Endocrinology and metabolism | 2009 |
|
Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats
A Bonen, GP Holloway, NN Tandon, XX Han, J McFarlan, JF Glatz, JJ Luiken |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2009 |
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Modulation of myocellular fat stores: lipid droplet dynamics in health and disease
RC Meex, P Schrauwen, MK Hesselink |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2009 |
|
Reduction of renal triglyceride accumulation: effects on proximal tubule Na + /H + exchange and urinary acidification
IA Bobulescu, M Dubree, J Zhang, P McLeroy, OW Moe |
American journal of physiology. Renal physiology | 2009 |
|
Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes
C Zhang, MS Yoon, J Chen |
American journal of physiology. Endocrinology and metabolism | 2009 |
|
Advances in Vascular Medicine
D Abraham, H Clive, M Dashwood, G Coghlan |
Advances in Vascular Medicine | 2009 |
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Live performance, carcass composition, and blood metabolite responses to dietary nutrient density in two distinct broiler breeds of male chickens
JP Zhao, JL Chen, GP Zhao, MQ Zheng, RR Jiang, J Wen |
Poultry science | 2009 |
|
Emergent Problems in Nonlinear Systems and Control
BK Ghosh, CF Martin, Y Zhou |
2009 | |
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Peak Growth Hormone-Releasing Hormone-Arginine-Stimulated Growth Hormone Is Inversely Associated with Intramyocellular and Intrahepatic Lipid Content in Premenopausal Women with Obesity
MA Bredella, M Torriani, BJ Thomas, RH Ghomi, DJ Brick, AV Gerweck, KK Miller |
The Journal of clinical endocrinology and metabolism | 2009 |
|
Adipophilin distribution and colocalization with lipid droplets in skeletal muscle.
Shaw CS, Sherlock M, Stewart PM, Wagenmakers AJ |
Histochemistry and Cell Biology | 2009 |
|
Adipocyte fatty acid binding protein during refeeding of female patients with anorexia nervosa.
Engl J, Tschoner A, Willis M, Schuster I, Kaser S, Laimer M, Biebl W, Patsch JR, Mangweth B, Ebenbichler CF |
European Journal of Nutrition | 2009 |
|
FSP27 contributes to efficient energy storage in white adipocytes by promoting unilocular lipid droplet formation
Naonobu Nishino, Yoshikazu Tamori, Sanshiro Tateya, Takayuki Kawaguchi, Tetsuro Shibakusa, Wataru Mizunoya, Kazuo Inoue, Riko Kitazawa, Sohei Kitazawa, Yasushi Matsuki, Ryuji Hiramatsu, Satoru Masubuchi, Asako Omachi, Kazuhiro Kimura, Masayuki Saito, Taku Amo, Shigeo Ohta, Tomohiro Yamaguchi, Takashi Osumi, Jinglei Cheng, Toyoshi Fujimoto, Harumi Nakao, Kazuki Nakao, Atsu Aiba, Hitoshi Okamura, Tohru Fushiki, Masato Kasuga |
Journal of Clinical Investigation | 2008 |
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Lower intrinsic ADP-stimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of type 2 diabetic patients
E. Phielix, V.B. Schrauwen-Hinderling, M. Mensink, E. Lenaers, R. Meex, J. Hoeks, M.E. Kooi, E. Kornips, JP. Sels, M.K.C. Hesselink, P. Schrauwen |
2008 | |
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Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism
H Chen, D Simar, K Lambert, J Mercier, MJ Morris |
Endocrinology | 2008 |
|
Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis
N Anderson, J Borlak |
Pharmacological reviews | 2008 |
|
Muscle-Specific IRS-1 Ser->Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
K Morino, S Neschen, S Bilz, S Sono, D Tsirigotis, RM Reznick, I Moore, Y Nagai, V Samuel, D Sebastian, M White, W Philbrick, GI Shulman |
Diabetes | 2008 |
|
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
KA Posey, DJ Clegg, RL Printz, J Byun, GJ Morton, A Vivekanandan-Giri, S Pennathur, DG Baskin, JW Heinecke, SC Woods, MW Schwartz, KD Niswender |
American journal of physiology. Endocrinology and metabolism | 2008 |
|
Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects
SM Reyna, S Ghosh, P Tantiwong, CS Meka, P Eagan, CP Jenkinson, E Cersosimo, RA DeFronzo, DK Coletta, A Sriwijitkamol, N Musi |
Diabetes | 2008 |
|
Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism
CS Choi, DE Befroy, R Codella, S Kim, RM Reznick, YJ Hwang, ZX Liu, HY Lee, A Distefano, VT Samuel, D Zhang, GW Cline, C Handschin, J Lin, KF Petersen, BM Spiegelman, GI Shulman |
Proceedings of the National Academy of Sciences | 2008 |
|
Partial Resistance to Peroxisome Proliferator-Activated Receptor- Agonists in ZDF Rats Is Associated With Defective Hepatic Mitochondrial Metabolism
S Satapati, T He, T Inagaki, M Potthoff, ME Merritt, V Esser, DJ Mangelsdorf, SA Kliewer, JD Browning, SC Burgess |
Diabetes | 2008 |
|
Treatment options for nonalcoholic Fatty liver disease
S Chitturi |
Therapeutic advances in gastroenterology | 2008 |
|
Resistance to High-Fat Diet-Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): A New Model of Partial Lipodystrophy
JA Villena, CS Choi, Y Wang, S Kim, YJ Hwang, YB Kim, G Cline, GI Shulman, HS Sul |
Diabetes | 2008 |
|
Pioglitazone Decreases Fasting and Postprandial Endogenous Glucose Production in Proportion to Decrease in Hepatic Triglyceride Content
B Ravikumar, J Gerrard, CD Man, MJ Firbank, A Lane, PT English, C Cobelli, R Taylor |
Diabetes | 2008 |
|
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
A Guilherme, JV Virbasius, V Puri, MP Czech |
Nature Reviews Molecular Cell Biology | 2008 |
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American College of Endocrinology Pre-Diabetes Consensus Conference: Part Three
ZT Bloomgarden |
Diabetes care | 2008 |
|
Crucial role of insulin receptor substrate-2 in compensatory β-cell hyperplasia in response to high fat diet-induced insulin resistance
I Takamoto, Y Terauchi, N Kubota, M Ohsugi, K Ueki, T Kadowaki |
Diabetes, Obesity and Metabolism | 2008 |
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Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress
M Delibegovic, D Zimmer, C Kauffman, K Rak, EG Hong, YR Cho, JK Kim, BB Kahn, BG Neel, KK Bence |
Diabetes | 2008 |
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Oxidation of Intracellular and Extracellular Fatty Acids in Skeletal Muscle: Application of kinetic modeling, stable isotopes and liquid chromatography/electrospray ionization ion-trap tandem mass spectrometry technology
J Xu, L Zhou, XM Persson, P Balagopal, MD Jensen, Z Guo |
European Journal of Lipid Science and Technology | 2008 |
|
The role of skeletal muscle sphingolipids in the development of insulin resistance
M Straczkowski, I Kowalska |
The review of diabetic studies : RDS | 2008 |
|
Thiazolidinediones: effects on insulin resistance and the cardiovascular system
CE Quinn, PK Hamilton, CJ Lockhart, GE McVeigh |
British Journal of Pharmacology | 2008 |
|
Effect of renal lipid accumulation on proximal tubule Na+/H+ exchange and ammonium secretion
IA Bobulescu, M Dubree, J Zhang, P McLeroy, OW Moe |
American journal of physiology. Renal physiology | 2008 |
|
A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity
SN Vallerie, M Furuhashi, R Fucho, GS Hotamisligil |
PloS one | 2008 |
|
Obesity and T2DM in Youth
R Weiss, S Caprio |
Endocrine Research | 2008 |
|
Glycerolipid Metabolism and Signaling in Health and Disease
M Prentki, SR Madiraju |
Endocrine reviews | 2008 |
|
Consequences of Lipid Droplet Coat Protein Downregulation in Liver Cells: Abnormal Lipid Droplet Metabolism and Induction of Insulin Resistance
M Bell, H Wang, H Chen, JC McLenithan, DW Gong, RZ Yang, D Yu, SK Fried, MJ Quon, C Londos, C Sztalryd |
Diabetes | 2008 |
|
Blood Viscosity and Hematocrit as Risk Factors for Type 2 Diabetes Mellitus: The Atherosclerosis Risk in Communities (ARIC) Study
LJ Tamariz, JH Young, JS Pankow, HC Yeh, MI Schmidt, B Astor, FL Brancati |
American Journal of Epidemiology | 2008 |
|
Metabolic Complications of Childhood Obesity: Identifying and mitigating the risk
R Weiss, FR Kaufman |
Diabetes care | 2008 |
|
Inhibition of ADRP prevents diet-induced insulin resistance
GM Varela, DA Antwi, R Dhir, X Yin, NS Singhal, MJ Graham, RM Crooke, RS Ahima |
American journal of physiology. Gastrointestinal and liver physiology | 2008 |
|
Cellular retinol-binding protein type III is a PPARgamma target gene and plays a role in lipid metabolism
CF Zizola, GJ Schwartz, S Vogel |
American journal of physiology. Endocrinology and metabolism | 2008 |
|
Glycéronéogenèse et PEPCK-C: Cibles pharmacologiques dans le diabète de type 2
T Cadoudal, F Fouque, C Benelli, C Forest |
médecine/sciences | 2008 |
|
A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle
EL Glynn, HL Lujan, VJ Kramer, MJ Drummond, SE DiCarlo, BB Rasmussen |
Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme | 2008 |
|
APPL1: role in adiponectin signaling and beyond
SS Deepa, LQ Dong |
American journal of physiology. Endocrinology and metabolism | 2008 |
|
Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes
HM Feyter, E Lenaers, SM Houten, P Schrauwen, MK Hesselink, RJ Wanders, K Nicolay, JJ Prompers |
The FASEB Journal | 2008 |
|
AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5
SL McGee, BJ van Denderen, KF Howlett, J Mollica, JD Schertzer, BE Kemp, M Hargreaves |
Diabetes | 2008 |
|
Hormonal regulation of intracellular lipolysis in C57BL/6J mice: effect of diet-induced adiposity and data normalization
IR Bederman, SF Previs |
Metabolism | 2008 |
|
Nicotinic Acid: Pharmacological Effects and Mechanisms of Action
A Gille, ET Bodor, K Ahmed, S Offermanns |
Annual Review of Pharmacology and Toxicology | 2008 |
|
Fatty liver, insulin resistance, and dyslipidemia
M Adiels, MR Taskinen, J Borén |
Current Diabetes Reports | 2008 |
|
Improvement of dyslipidemia, insulin sensitivity, and energy balance by a peroxisome proliferator–activated receptor α agonist
X Chen, J Matthews, L Zhou, P Pelton, Y Liang, J Xu, M Yang, E Cryan, P Rybczynski, K Demarest |
Metabolism | 2008 |
|
Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
DM Muoio, CB Newgard |
Nature Reviews Molecular Cell Biology | 2008 |
|
Lipid accumulation in non-adipose tissue and lipotoxicity
NA Herpen, VB Schrauwen-Hinderling |
Physiology & Behavior | 2008 |
|
Peroxisome proliferator-activated receptor gamma agonism modifies the effects of growth hormone on lipolysis and insulin sensitivity
MB Krag, S Nielsen, ZK Guo, SB Pedersen, O Schmitz, JS Christiansen, JO Jørgensen |
Clinical Endocrinology | 2008 |
|
Homeostasis Model Assessment (HOMA) as Surrogate Insulinization Criteria in Patients With Type 2 Diabetes
V Bermúdez, R Cano, C Cano, F Bermúdez, E Leal, K Acosta, E Mengual, N Arraiz, C Briceño, J Gómez, M Bustamante, D Aparicio, M Cabrera, L Valdelamar, M Rodriguez, V Manuel, R Hernández |
American Journal of Therapeutics | 2008 |
|
Impact of body weight, diet and lifestyle on nonalcoholic fatty liver disease
H Cortez-Pinto, M Machado |
Expert Review of Gastroenterology & Hepatology | 2008 |
|
Obesity in children and adolescents
AM Cali, S Caprio |
The Journal of clinical endocrinology and metabolism | 2008 |
|
Dramatic reversal of derangements in muscle metabolism and left ventricular function after bariatric surgery
JG Leichman, EB Wilson, T Scarborough, D Aguilar, CC 3rd, S Yu, MF Algahim, M Reyes, FG Moody, H Taegtmeyer |
The American Journal of Medicine | 2008 |
|
Fat infiltration in muscle: new evidence for familial clustering and associations with diabetes
I Miljkovic-Gacic, X Wang, CM Kammerer, CL Gordon, CH Bunker, LH Kuller, AL Patrick, VW Wheeler, RW Evans, JM Zmuda |
Obesity (Silver Spring, Md.) | 2008 |
|
Resistance training and timed essential amino acids protect against the loss of muscle mass and strength during 28 days of bed rest and energy deficit
N Brooks, GJ Cloutier, SM Cadena, JE Layne, CA Nelsen, AM Freed, R Roubenoff, C Castaneda-Sceppa |
Journal of applied physiology | 2008 |
|
Crocetin improves the insulin resistance induced by high-fat diet in rats
L Sheng, Z Qian, Y Shi, L Yang, L Xi, B Zhao, X Xu, H Ji |
British Journal of Pharmacology | 2008 |
|
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice
DB Savage, L Zhai, B Ravikumar, CS Choi, JE Snaar, AC McGuire, SE Wou, G Medina-Gomez, S Kim, CB Bock, DM Segvich, B Solanky, D Deelchand, A Vidal-Puig, NJ Wareham, GI Shulman, F Karpe, R Taylor, BA Pederson, PJ Roach, S O'Rahilly, AA DePaoli-Roach |
PLoS Medicine | 2008 |
|
Gender alters the effects of palmitate and oleate on fat oxidation and energy expenditure
CL Kien, JY Bunn |
Obesity (Silver Spring, Md.) | 2008 |
|
Beta-glucans in the treatment of diabetes and associated cardiovascular risks
J Chen, K Raymond |
Vascular Health and Risk Management | 2008 |
|
A potential role for skeletal muscle caveolin-1 as an insulin sensitivity modulator in ageing-dependent non-obese type 2 diabetes: studies in a new mouse model
YS Oh, LY Khil, KA Cho, SJ Ryu, MK Ha, GJ Cheon, TS Lee, JW Yoon, HS Jun, SC Park |
Diabetologia | 2008 |
|
Metabolic rate and vascular function are reduced in women with a family history of type 2 diabetes mellitus
JL Olive, KD Ballard, JJ Miller, BA Milliner |
Metabolism | 2008 |
|
Corticosterone administration and dietary glucose supplementation enhance fat accumulation in broiler chickens
KJ Jiang, HC Jiao, ZG Song, L Yuan, JP Zhao, H Lin |
British Poultry Science | 2008 |
|
Scanning Electron Microscopic Analysis of Intramyocellular Lipid Droplets in an Animal Model of Type 2 Diabetes
M Fraenkel, R Weiss, I Leizerman, D Anaby, E Golomb, G Leibowitz, N Kaiser |
Obesity | 2008 |
|
Determinants of Insulin-resistant Phenotypes in Normal-weight and Obese Black African Women
CL Jennings, EV Lambert, M Collins, Y Joffe, NS Levitt, JH Goedecke |
Obesity | 2008 |
|
What are the Biochemical Mechanisms Responsible for Enhanced Fatty Acid Utilization by Perfused Hearts from Type 2 Diabetic db/db Mice?
AN Carley, DL Severson |
Cardiovascular Drugs and Therapy | 2008 |
|
Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a
AR Cameron, S Anton, L Melville, NP Houston, S Dayal, GJ McDougall, D Stewart, G Rena |
Aging Cell | 2008 |
|
Stearoyl-CoA desaturase: A novel control point of lipid metabolism and insulin sensitivity
P Dobrzyn, JM Ntambi, A Dobrzyn |
European Journal of Lipid Science and Technology | 2008 |
|
Adiponectin and Resistin Response in the Onset of Obesity in Male and Female Rats
J Ribot, AM Rodríguez, E Rodríguez, A Palou |
Obesity | 2008 |
|
Dorothy Hodgkin Lecture 2008 Gastric inhibitory polypeptide (GIP) revisited: a new therapeutic target for obesitydiabetes?
PR Flatt |
Diabetic Medicine | 2008 |
|
Free fatty acids and skeletal muscle insulin resistance
EW Kraegen, GJ Cooney |
Current Opinion in Lipidology | 2008 |
|
Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes
CM Blouin, SL Lay, F Lasnier, I Dugail, E Hajduch |
Biochemical and Biophysical Research Communications | 2008 |
|
A high-fructose diet impairs basal and stress-mediated lipid metabolism in healthy male subjects
A Abdel-Sayed, C Binnert, KA Lê, M Bortolotti, P Schneiter, L Tappy |
British Journal of Nutrition | 2008 |
|
Adipokines--targeting a root cause of cardiometabolic risk
A Bakhai |
QJM | 2008 |
|
Olanzapine inhibits glycogen synthase kinase-3β: An investigation by docking simulation and experimental validation
MK Mohammad, IM Al-masri, MO Taha, MA Al-Ghussein, HS AlKhatib, S Najjar, Y Bustanji |
European Journal of Pharmacology | 2008 |
|
Dietary Fructose During the Suckling Period Increases Body Weight and Fatty Acid Uptake Into Skeletal Muscle in Adult Rats
M Huynh, JJ Luiken, W Coumans, RC Bell |
Obesity | 2008 |
|
Review article: diagnosis and treatment of non-alcoholic fatty liver disease
MK Oh, J Winn, F Poordad |
Alimentary Pharmacology & Therapeutics | 2008 |
|
Beneficial role of l-arginine in cardiac matrix remodelling in insulin resistant rats
LD Monti, E Galluccio, P Lucotti, E Setola, S Costa, B Fontana, M Oldani, D Merante, PD Blasi, E Bosi, PM Piatti |
European Journal of Clinical Investigation | 2008 |
|
Metabolic Syndrome and Insulin Resistance
HS Bagry, S Raghavendran, F Carli |
Anesthesiology | 2008 |
|
The Relationship Between Diabetes Mellitus and Traffic-Related Air Pollution
RD Brook, M Jerrett, JR Brook, RL Bard, MM Finkelstein |
Journal of Occupational and Environmental Medicine | 2008 |
|
AMP-Activated Protein Kinase Activation by 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) Inhibits Palmitate-Induced Endothelial Cell Apoptosis Through Reactive Oxygen Species Suppression
JE Kim, YW Kim, IK Lee, JY Kim, YJ Kang, SY Park |
Journal of Pharmacological Sciences | 2008 |
|
The other lipids: Ectopic lipids with emphasis on skeletal muscle
LC Luu, E Ravussin |
Current Cardiovascular Risk Reports | 2008 |
|
Arachidonic acid and glucose uptake by freshly isolated human adipocytes
AC Malipa, RA Meintjes, M Haag |
Cell Biochemistry and Function | 2008 |
|
Diabetes-related metabolic perturbations in cardiac myocyte
D Feuvray, A Darmellah |
Diabetes & Metabolism | 2008 |
|
Palmitic and Linoleic Acids Impair Endothelial Progenitor Cells by Inhibition of Akt/eNOS Pathway
Wei-Xin Guo, Qi-Dong Yang, Yun-Hai Liu, Xiao-Yun Xie, Wang-Miao, Rui-Chao Niu |
Archives of Medical Research | 2008 |
|
The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS
T Kadowaki, T Yamauchi, N Kubota |
FEBS Letters | 2008 |
|
Epidemiology of Pediatric and Adolescent Diabetes
M Vaxillaire, P Froguel |
Epidemiology of Pediatric and Adolescent Diabetes | 2008 |
|
Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats
S Zhang, GA Gowda, V Asiago, N Shanaiah, C Barbas, D Raftery |
Analytical Biochemistry | 2008 |
|
Improving Insulin Sensitivity: A Review of New Therapies
MK Rhee, GE Umpierrez |
Clinical Cornerstone | 2008 |
|
Les actions physiologiques de l’insuline
J Girard |
Médecine des Maladies Métaboliques | 2008 |
|
Peri-implantation and late gestation maternal undernutrition differentially affect fetal sheep skeletal muscle development: Maternal undernutrition and fetal skeletal muscle development
PM Costello, A Rowlerson, NA Astaman, FE Anthony, AA Sayer, C Cooper, MA Hanson, LR Green |
The Journal of Physiology | 2008 |
|
Atrial Natriuretic Peptide Induces Postprandial Lipid Oxidation in Humans
AL Birkenfeld, P Budziarek, M Boschmann, C Moro, F Adams, G Franke, M Berlan, MA Marques, FC Sweep, FC Luft, M Lafontan, J Jordan |
Diabetes | 2008 |
|
Skeletal Muscle Metabolic Dysfunction in Obesity and Metabolic Syndrome
GD Wells, MD Noseworthy, J Hamilton, M Tarnopolski, I Tein |
CAN J NEUROL SCI | 2008 |
|
Review: Treatment options for nonalcoholic fatty liver disease
S Chitturi |
Therapeutic advances in gastroenterology | 2008 |
|
A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity
SN Vallerie, M Furuhashi, R Fucho, GS Hotamisligil, K Maedler |
PloS one | 2008 |
|
Metabolic syndrome and incidence of type 2 diabetes in patients with manifest vascular disease
AM Wassink, YV der Graaf, SS Soedamah-Muthu, W Spiering, FL Visseren |
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease | 2008 |
|
Insulin Resistance in Striated Muscle-specific Integrin Receptor β1-deficient Mice
H Zong, CC Bastie, J Xu, R Fassler, KP Campbell, IJ Kurland, JE Pessin |
The Journal of biological chemistry | 2008 |
|
Setting the stage: possible mechanisms by which acute contraction restores insulin sensitivity in muscle
JP Thyfault |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2008 |
|
Liver fat, visceral adiposity, and sleep disturbances contribute to the development of insulin resistance and glucose intolerance in nondiabetic dialysis patients
GK Sakkas, C Karatzaferi, E Zintzaras, CD Giannaki, V Liakopoulos, E Lavdas, E Damani, N Liakos, I Fezoulidis, Y Koutedakis, I Stefanidis |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2008 |
|
Skeletal muscle lipid oxidation and obesity: influence of weight loss and exercise
JR Berggren, KE Boyle, WH Chapman, JA Houmard |
American journal of physiology. Endocrinology and metabolism | 2008 |
|
Cellular retinol-binding protein type III is a PPARγ target gene and plays a role in lipid metabolism
CF Zizola, GJ Schwartz, S Vogel |
American journal of physiology. Endocrinology and metabolism | 2008 |
|
Effect of renal lipid accumulation on proximal tubule Na + /H + exchange and ammonium secretion
IA Bobulescu, M Dubree, J Zhang, P McLeroy, OW Moe |
American journal of physiology. Renal physiology | 2008 |
|
Resistance training and timed essential amino acids protect against the loss of muscle mass and strength during 28 days of bed rest and energy deficit
N Brooks, GJ Cloutier, SM Cadena, JE Layne, CA Nelsen, AM Freed, R Roubenoff, C Castaneda-Sceppa |
Journal of applied physiology | 2008 |
|
Cardiovascular Risk Factors and the Metabolic Syndrome in Pediatric Nonalcoholic Fatty Liver Disease
JB Schwimmer, PE Pardee, JE Lavine, AK Blumkin, S Cook |
Circulation | 2008 |
|
Levels of plasma insulin, leptin and adiponectin, and activities of key enzymes in carbohydrate metabolism in skeletal muscle and liver in fasted ICR mice fed dietary n-3 polyunsaturated fatty acids
T Higuchi, N Shirai, M Saito, H Suzuki, Y Kagawa |
The Journal of Nutritional Biochemistry | 2008 |
|
Type 2 Diabetes Mellitus
MN Feinglos, MA Bethel |
2008 | |
|
Genomics in Endocrinology
S Handwerger, B Aronow |
2008 | |
|
Pancreatic Beta Cell in Health and Disease
S Seino, GI Bell |
2008 | |
|
The Metabolic Syndrome in Clinical Practice
S Mittal |
2008 | |
|
Validated Comprehensive Analytical Method for Quantification of Coenzyme A Activated Compounds in Biological Tissues by Online Solid-Phase Extraction LC/MS/MS
C Magnes, M Suppan, TR Pieber, T Moustafa, M Trauner, FM Sinner |
Analytical Chemistry | 2008 |
|
Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function.
Larson-Meyer DE, Newcomer BR, Heilbronn LK, Volaufova J, Smith SR, Alfonso AJ, Lefevre M, Rood JC, Williamson DA, Ravussin E |
Obesity (Silver Spring, Md.) | 2008 |
|
Requirement for glucokinase Irs2 in order to achieve compensatory beta-cell hyperplasia in response to high-fat-diet-induced insulin resistance
Yasuo Terauchi, Iseki Takamoto, Naoto Kubota, Junji Matsui, Ryo Suzuki, Kajuro Komeda, Akemi Hara, Yukiyasu Toyoda, Ichitomo Miwa, Shinichi Aizawa, Shuichi Tsutsumi, Yoshiharu Tsubamoto, Shinji Hashimoto, Kazuhiro Eto, Akinobu Nakamura, Mitsuhiko Noda, Kazuyuki Tobe, Hiroyuki Aburatani, Ryozo Nagai, Takashi Kadowaki |
Journal of Clinical Investigation | 2007 |
|
Mechanism by Which Overexpression of Uncoupling Protein 3 in Skeletal Muscle Protects Against Fat-Induced Insulin Resistance
Cheol Soo Choi, Jonathan J. Fillmore, Jason K. Kim, Zhen-Xiang Liu, Sheene Kim, Emily F. Collier, Ameya Kulkarni, Alberto Distefano, Yu-Jin Hwang, Mario Kahn, Yan Chen, Chunli Yu, Irene K. Moore, Richard M. Reznick, Takamasa Higashimori, Gerald I. Shulman |
Journal of Clinical Investigation | 2007 |
|
Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B
M Delibegovic, KK Bence, N Mody, EG Hong, HJ Ko, JK Kim, BB Kahn, BG Neel |
Molecular and cellular biology | 2007 |
|
Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance
D Zhang, ZX Liu, CS Choi, L Tian, R Kibbey, J Dong, GW Cline, PA Wood, GI Shulman |
Proceedings of the National Academy of Sciences | 2007 |
|
Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance
CA Nagle, J An, M Shiota, TP Torres, GW Cline, ZX Liu, S Wang, RL Catlin, GI Shulman, CB Newgard, RA Coleman |
The Journal of biological chemistry | 2007 |
|
Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes
YR Cho, HJ Kim, SY Park, HJ Ko, EG Hong, T Higashimori, Z Zhang, DY Jung, MS Ola, KF Lanoue, EH Leiter, JK Kim |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Short-term in vitro inhibition of glycogen synthase kinase 3 potentiates insulin signaling in type I skeletal muscle of Zucker Diabetic Fatty rats
EJ Henriksen, MK Teachey |
Metabolism: clinical and experimental | 2007 |
|
Disordered lipid metabolism and the pathogenesis of insulin resistance
DB Savage, KF Petersen, GI Shulman |
Physiological reviews | 2007 |
|
Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients
DE Befroy, KF Petersen, S Dufour, GF Mason, RA de Graaf, DL Rothman, GI Shulman |
Diabetes | 2007 |
|
Association analysis indicates that a variant GATA-binding site in the PIK3CB promoter is a Cis-acting expression quantitative trait locus for this gene and attenuates insulin resistance in obese children
CL Stunff, A Dechartres, V Mariot, C Lotton, C Trainor, EM Giudice, D Meyre, I Bieche, I Laurendeau, P Froguel, D Zelenika, D Fallin, M Lathrop, PH Roméo, P Bougnères |
Diabetes | 2007 |
|
Continuous fat oxidation in acetyl CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity
CS Choi, DB Savage, L Abu-Elheiga, ZX Liu, S Kim, A Kulkarni, A Distefano, YJ Hwang, RM Reznick, R Codella, D Zhang, GW Cline, SJ Wakil, GI Shulman |
Proceedings of the National Academy of Sciences | 2007 |
|
n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator-Activated Receptor- -Dependent Manner
S Neschen, K Morino, J Dong, Y Wang-Fischer, GW Cline, AJ Romanelli, JC Rossbacher, IK Moore, W Regittnig, DS Munoz, JH Kim, GI Shulman |
Diabetes | 2007 |
|
High Visceral and Low Abdominal Subcutaneous Fat Stores in the Obese Adolescent: A Determinant of an Adverse Metabolic Phenotype
SE Taksali, S Caprio, J Dziura, S Dufour, AM Cali, TR Goodman, X Papademetris, TS Burgert, BM Pierpont, M Savoye, M Shaw, AA Seyal, R Weiss |
Diabetes | 2007 |
|
Treating insulin resistance: future prospects
CJ Bailey |
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease | 2007 |
|
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
T Yamauchi, Y Nio, T Maki, M Kobayashi, T Takazawa, M Iwabu, M Okada-Iwabu, S Kawamoto, N Kubota, T Kubota, Y Ito, J Kamon, A Tsuchida, K Kumagai, H Kozono, Y Hada, H Ogata, K Tokuyama, M Tsunoda, T Ide, K Murakami, M Awazawa, I Takamoto, P Froguel, K Hara, K Tobe, R Nagai, K Ueki, T Kadowaki |
Nature Medicine | 2007 |
|
The endoplasmic reticulum and the unfolded protein response
JD Malhotra, RJ Kaufman |
Seminars in Cell & Developmental Biology | 2007 |
|
Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Cycle or a Double-Edged Sword?
JD Malhotra, RJ Kaufman |
Antioxidants & Redox Signaling | 2007 |
|
Adipocytokines and the Regulation of Lipid Metabolism in Growth Hormone Transgenic and Calorie-Restricted Mice
Z Wang, MM Masternak, KA Al-Regaiey, A Bartke |
Endocrinology | 2007 |
|
Functional Studies of Akt Isoform Specificity in Skeletal Muscle in Vivo; Maintained Insulin Sensitivity Despite Reduced Insulin Receptor Substrate-1 Expression
ME Cleasby, TA Reinten, GJ Cooney, DE James, EW Kraegen |
Molecular Endocrinology | 2007 |
|
Palmitate Induced Mitochondrial Deoxyribonucleic Acid Damage and Apoptosis in L6 Rat Skeletal Muscle Cells
LI Rachek, SI Musiyenko, SP LeDoux, GL Wilson |
Endocrinology | 2007 |
|
Adipocyte, Adipose Tissue, and Infectious Disease
MS Desruisseaux, Nagajyothi, ME Trujillo, HB Tanowitz, PE Scherer |
Infection and immunity | 2007 |
|
Crocetin attenuates palmitate-induced insulin insensitivity and disordered tumor necrosis factor-alpha and adiponectin expression in rat adipocytes
L Xi, Z Qian, G Xu, C Zhou, S Sun |
British Journal of Pharmacology | 2007 |
|
TXNIP regulates peripheral glucose metabolism in humans
H Parikh, E Carlsson, WA Chutkow, LE Johansson, H Storgaard, P Poulsen, R Saxena, C Ladd, PC Schulze, MJ Mazzini, CB Jensen, A Krook, M Björnholm, H Tornqvist, JR Zierath, M Ridderstråle, D Altshuler, RT Lee, A Vaag, LC Groop, VK Mootha |
PLoS Medicine | 2007 |
|
Acute suppression of VLDL1 secretion rate by insulin is associated with hepatic fat content and insulin resistance
M Adiels, J Westerbacka, A Soro-Paavonen, AM Häkkinen, S Vehkavaara, MJ Caslake, C Packard, SO Olofsson, H Yki-Järvinen, MR Taskinen, J Borén |
Diabetologia | 2007 |
|
Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose intolerance and associated disturbances in mice fed high-fat and cafeteria diets
VA Gault, PL McClean, RS Cassidy, N Irwin, PR Flatt |
Diabetologia | 2007 |
|
Intramyocellular lipid kinetics and insulin resistance
ZK Guo |
Lipids in Health and Disease | 2007 |
|
Involvement of the PA28γ-Dependent Pathway in Insulin Resistance Induced by Hepatitis C Virus Core Protein
H Miyamoto, K Moriishi, K Moriya, S Murata, K Tanaka, T Suzuki, T Miyamura, K Koike, Y Matsuura |
Journal of virology | 2007 |
|
Pathways involved in lipid-induced insulin resistance in obesity
MJ Watt, GR Steinberg |
Future Lipidology | 2007 |
|
Growth Hormone and Insulin Resistance
JO Jørgensen, RL Larsen, L Møller, M Krag, N Jessen, H Nørrelund, JS Christiansen, N Møller |
Hormone Research | 2007 |
|
Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1α: implications for metabolic disease
DM Muoio, TR Koves |
Applied Physiology, Nutrition, and Metabolism | 2007 |
|
The potential role of olive oil-derived MUFA in insulin sensitivity
AC Tierney, HM Roche |
Molecular Nutrition & Food Research | 2007 |
|
Novel food ingredients for weight control
G Gerstner, M Vrese |
Novel food ingredients for weight control | 2007 |
|
How Effective Are Lifestyle Changes in the Prevention of Type 2 Diabetes Mellitus?
FX Pi-Sunyer |
Nutrition Reviews | 2007 |
|
The metabolic syndrome: metabolic changes with vascular consequences
AM Wassink, JK Olijhoek, FL Visseren |
European Journal of Clinical Investigation | 2007 |
|
The effect of exercise, training, and inactivity on insulin sensitivity in diabetics and their relatives: what is new?
T Østergård, N Jessen, O Schmitz, LJ Mandarino |
Applied Physiology, Nutrition, and Metabolism | 2007 |
|
Insulin Resistance as the Underlying Cause for the Metabolic Syndrome
D Lann, D LeRoith |
Medical Clinics of North America | 2007 |
|
Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats
MG Sridhar, R Vinayagamoorthi, VA Suyambunathan, Z Bobby, N Selvaraj |
British Journal of Nutrition | 2007 |
|
Plasma and urine levels of resistin and adiponectin in chronic kidney disease
S Yaturu, RD Reddy, J Rains, SK Jain |
Cytokine | 2007 |
|
Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists
MM Pelsers, K Tsintzas, H Boon, K Jewell, L Norton, JJ Luiken, JF Glatz, LJ van Loon |
Acta Physiologica | 2007 |
|
Metformin Plus Low-Dose Glimeperide Significantly Improves Homeostasis Model Assessment for Insulin Resistance (HOMAIR) and ??-Cell Function (HOMA??-cell) Without Hyperinsulinemia in Patients With Type 2 Diabetes Mellitus
VJ Berm??dez-Pirela, C Cano, MT Medina, A Souki, MA Lemus, EM Leal, HA Seyfi, R Cano, A Ciscek, F Berm??dez-Arias, F Contreras, ZH Israili, R Hern??ndez-Hern??ndez, M Valasco |
American Journal of Therapeutics | 2007 |
|
Mitochondrial dysfunction and insulin resistance: a matter of lifestyle?
KA L??, L Tappy, DA D??Alessio |
Current Opinion in Clinical Nutrition and Metabolic Care | 2007 |
|
Intramyocellular lipids: maker vs. marker of insulin resistance
Z Guo |
Medical Hypotheses | 2007 |
|
Fatty liver in chronic hepatitis C infection: unravelling the mechanisms
JA Oben, E Paulon |
Gut | 2007 |
|
Interethnic differences in muscle, liver and abdominal fat partitioning in obese adolescents
D Liska, S Dufour, TL Zern, S Taksali, AM Calí, J Dziura, GI Shulman, BM Pierpont, S Caprio |
PloS one | 2007 |
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The glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytes
C Yu, J Cresswell, MG Löffler, JS Bogan |
The Journal of biological chemistry | 2007 |
|
High-fat diet, muscular lipotoxicity and insulin resistance
P Schrauwen |
Proceedings of the Nutrition Society | 2007 |
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Effect of nutritional support on glucose control
G Seematter, L Tappy |
Current Opinion in Clinical Nutrition and Metabolic Care | 2007 |
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Activation of μ-opioid receptors improves insulin sensitivity in obese Zucker rats
TF Tzeng, CY Lo, JT Cheng, IM Liu |
Life Sciences | 2007 |
|
Dipeptidyl Peptidase IV Inhibitors and the Incretin System in Type 2 Diabetes Mellitus
AK Langley, TJ Suffoletta, HR Jennings |
Pharmacotherapy | 2007 |
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Respuestas cardiovasculares al NaCl hipertónico inyectado en la región anteroventral del tercer ventrículo de ratas con hipertensión e insulinorresistencia inducidas por fructosa
FJ Rosa, E Romero-Vecchione, J Vásquez, R Antequera, M Strauss |
Revista Española de Cardiología | 2007 |
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Effect of vanadate on gene expression of the insulin signaling pathway in skeletal muscle of streptozotocin-induced diabetic rats
D Wei, M Li, W Ding |
JBIC Journal of Biological Inorganic Chemistry | 2007 |
|
Carnitine revisited: potential use as adjunctive treatment in diabetes
RA Power, MW Hulver, JY Zhang, J Dubois, RM Marchand, O Ilkayeva, DM Muoio, RL Mynatt |
Diabetologia | 2007 |
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Adiponectin and the cardiovascular system: from risk to disease
R Tarquini, C Lazzeri, G Laffi, GF Gensini |
Internal and Emergency Medicine | 2007 |
|
Network distribution of mitochondria and lipid droplets in human muscle fibres
CS Shaw, DA Jones, AJ Wagenmakers |
Histochemistry and Cell Biology | 2007 |
|
Fatty acid represses insulin receptor gene expression by impairing HMGA1 through protein kinase Cε
D Dey, A Bhattacharya, SS Roy, S Bhattacharya |
Biochemical and Biophysical Research Communications | 2007 |
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Résistance à l’insuline et alimentation
V Makoundou, A Golay |
Obésité | 2007 |
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Kinase-dependent pathways and the development of insulin resistance in hepatocytes
CM Rondinone |
Expert Review of Endocrinology & Metabolism | 2007 |
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Effects of pioglitazone and metformin on intracellular lipid content in liver and skeletal muscle of individuals with type 2 diabetes mellitus
T Teranishi, T Ohara, K Maeda, M Zenibayashi, K Kouyama, Y Hirota, H Kawamitsu, M Fujii, K Sugimura, M Kasuga |
Metabolism | 2007 |
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Changes in the Expression of Hypothalamic Lipid Sensing Genes in Rat Model of Intrauterine Growth Retardation (IUGR)
A Puglianiello, D Germani, S Antignani, GS Tomba, S Cianfarani |
Pediatric Research | 2007 |
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Mechanisms underlying fat-induced hepatic insulin resistance
E Park, A Giacca |
Future Lipidology | 2007 |
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Targeting PGC-1α to control energy homeostasis
Z Wu, O Boss |
Expert Opinion on Therapeutic Targets | 2007 |
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Identification of peroxisome-proliferator responsive element in the mouse HSL gene
H Yajima, Y Kobayashi, T Kanaya, Y Horino |
Biochemical and Biophysical Research Communications | 2007 |
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Chronological Approach of Diet-induced Alterations in Muscle Mitochondrial Functions in Rats*
E Chanséaume, AL Tardy, J Salles, C Giraudet, P Rousset, A Tissandier, Y Boirie, B Morio |
Obesity | 2007 |
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Use of Insulin Sensitizers in NASH
M Khashab, N Chalasani |
Endocrinology & Metabolism Clinics of North America | 2007 |
|
Insulin resistance and acute coronary syndrome in the young Japanese population have a strong association
N Ikeda, R Nakajima, T Tsunoda, M Nakamura, K Sugi |
Heart and Vessels | 2007 |
|
Investigation of muscle lipid metabolism by localized one- and two-dimensional MRS techniques using a clinical 3T MRI/MRS scanner
SS Velan, C Durst, SK Lemieux, RR Raylman, R Sridhar, RG Spencer, GR Hobbs, MA Thomas |
Journal of Magnetic Resonance Imaging | 2007 |
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Overexpression of the phosphoprotein enriched in diabetes gene product (Ped/pea-15) in women with polycystic ovary syndrome
S Savastano, F Orio, S Palomba, T Cascella, F Manguso, GA Lupoli, P Formisano, G Lombardi, A Colao, F Beguinot, R Valentino |
Clinical Endocrinology | 2007 |
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Impaired glucose tolerance and risk factors for progression to type 2 diabetes in youth
R Weiss |
Pediatric Diabetes | 2007 |
|
Adiponectin gene therapy of streptozotocin-induced diabetic mice using hydrodynamic injection
M Fukushima, Y Hattori, H Tsukada, K Koga, E Kajiwara, K Kawano, T Kobayashi, K Kamata, Y Maitani |
The Journal of Gene Medicine | 2007 |
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Non-Alcoholic Fatty Liver Disease: Pathogenesis Directed Therapy – the Way Forward
NC McAvoy, A Lockman, PC Hayes |
Hungarian Medical Journal | 2007 |
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Lack of evident atherosclerosis despite multiple risk factors in glycogen storage disease type 1a with hyperadiponectinemia
M Tamaki, Y Tamura, T Ogihara, T Shimizu, H Uchino, T Hirose, R Kawamori, H Watada |
Metabolism | 2007 |
|
Antidiabetic effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats
H Yadav, S Jain, PR Sinha |
Nutrition | 2007 |
|
Myricetin, a naturally occurring flavonol, ameliorates insulin resistance induced by a high-fructose diet in rats
IM Liu, TF Tzeng, SS Liou, TW Lan |
Life Sciences | 2007 |
|
Type 2 diabetes mellitus: epidemiology, pathophysiology, unmet needs and therapeutical perspectives
M Virally, JF Blicklé, J Girard, S Halimi, D Simon, PJ Guillausseau |
Diabetes & Metabolism | 2007 |
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Insulin resistance in hepatocytes and sinusoidal liver cells: Mechanisms and consequences
IA Leclercq, AD Morais, B Schroyen, NV Hul, A Geerts |
Journal of Hepatology | 2007 |
|
Obesity After Spinal Cord Injury
DR Gater |
Physical medicine and rehabilitation clinics of North America | 2007 |
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Post-Genomic Cardiology
J Marín-García, MJ Goldenthal, GW Moe |
Post-Genomic Cardiology | 2007 |
|
Effect of gender on lipid-induced insulin resistance in obese subjects
B Vistisen, LI Hellgren, T Vadset, C Scheede-Bergdahl, JW Helge, F Dela, B Stallknecht |
European Journal of Endocrinology | 2007 |
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The relationship between the metabolic syndrome and energy-utilization deficit in the pathogenesis of obesity-induced osteoarthritis
J Rojas-Rodríguez, LE Escobar-Linares, M Garcia-Carrasco, RO Escárcega, S Fuentes-Alexandro, A Zamora-Ustaran |
Medical Hypotheses | 2007 |
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IGF-I treatment of insulin resistance
A McDonald, RM Williams, FM Regan, RK Semple, DB Dunger |
European Journal of Endocrinology | 2007 |
|
Fat distribution and storage: how much, where, and how?
R Weiss |
European Journal of Endocrinology | 2007 |
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Ubiquitinated-Protein Aggregates Form in Pancreatic -Cells During Diabetes-Induced Oxidative Stress and Are Regulated by Autophagy
NA Kaniuk, M Kiraly, H Bates, M Vranic, A Volchuk, JH Brumell |
Diabetes | 2007 |
|
Impaired Fat Oxidation After a Single High-Fat Meal in Insulin-Sensitive Nondiabetic Individuals With a Family History of Type 2 Diabetes
LK Heilbronn, S Gregersen, D Shirkhedkar, D Hu, LV Campbell |
Diabetes | 2007 |
|
Thematic review series: Adipocyte Biology. Adipose tissue function and plasticity orchestrate nutritional adaptation
JK Sethi, AJ Vidal-Puig |
Journal of lipid research | 2007 |
|
Symposium introduction: metabolic syndrome and the onset of cancer
JR Zhou, GL Blackburn, WA Walker |
The American journal of clinical nutrition | 2007 |
|
Integrative Medicine
D Cullum-Dugan, RB Saper |
Integrative Medicine | 2007 |
|
Pathogenesis of Type 2 Diabetes
M Stumvoll, BJ Goldstein, TW van Haeften |
Endocrine Research | 2007 |
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Dysregulation of muscle lipid metabolism in rats selectively bred for low aerobic running capacity
FJ Spargo, SL McGee, N Dzamko, MJ Watt, BE Kemp, SL Britton, LG Koch, M Hargreaves, JA Hawley |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Type 2 Diabetes: Principles and Practice, Second Edition
L Adams |
Type 2 Diabetes: Principles and Practice, Second Edition | 2007 |
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Alterations of glucose metabolism during treatment with clozapine or amisulpride: results from a prospective 16-week study
MA Rettenbacher, M Hummer, AL Hofer, S Baumgartner, C Ebenbichler, M EdLinger, G Kemmler, M Lechleitner, WW Fleischhacker |
Journal of Psychopharmacology (Oxford, England) | 2007 |
|
Interethnic Differences in Muscle, Liver and Abdominal Fat Partitioning in Obese Adolescents
D Liska, S Dufour, TL Zern, S Taksali, AM Calí, J Dziura, GI Shulman, BM Pierpont, S Caprio, W Isley |
PloS one | 2007 |
|
Glucose Regulates Diacylglycerol Intracellular Levels and Protein Kinase C Activity by Modulating Diacylglycerol Kinase Subcellular Localization
C Miele, F Paturzo, R Teperino, F Sakane, F Fiory, F Oriente, P Ungaro, R Valentino, F Beguinot, P Formisano |
The Journal of biological chemistry | 2007 |
|
Leptin, skeletal muscle lipids, and lipid-induced insulin resistance
JJ Dube, BA Bhatt, N Dedousis, A Bonen, RM O'Doherty |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2007 |
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Improvement of insulin sensitivity by antagonism of the renin-angiotensin system
EJ Henriksen |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2007 |
|
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
PL McClean, N Irwin, RS Cassidy, JJ Holst, VA Gault, PR Flatt |
American journal of physiology. Endocrinology and metabolism | 2007 |
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Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle
MC Levin, M Monetti, MJ Watt, MP Sajan, RD Stevens, JR Bain, CB Newgard, RV Farese, RV Farese |
American journal of physiology. Endocrinology and metabolism | 2007 |
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Metabolic challenges reveal impaired fatty acid metabolism and translocation of FAT/CD36 but not FABPpm in obese Zucker rat muscle
XX Han, A Chabowski, NN Tandon, J Calles-Escandon, JF Glatz, JJ Luiken, A Bonen |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Diet-induced modulation of mitochondrial activity in rat muscle
L Didier, B Yerby, R Deacon, J Gao |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women
GP Holloway, AB Thrush, GJ Heigenhauser, NN Tandon, DJ Dyck, A Bonen, LL Spriet |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients
M Cardellini, MA Marini, S Frontoni, ML Hribal, F Andreozzi, F Perticone, M Federici, D Lauro, G Sesti |
American journal of physiology. Endocrinology and metabolism | 2007 |
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Inactivation of PKCθ leads to increased susceptibility to obesity and dietary insulin resistance in mice
Z Gao, Z Wang, X Zhang, AA Butler, A Zuberi, B Gawronska-Kozak, M Lefevre, D York, E Ravussin, HR Berthoud, O McGuinness, WT Cefalu, J Ye |
American journal of physiology. Endocrinology and metabolism | 2007 |
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Long-chain n-3 polyunsaturated fatty acids dissociate phosphorylation of Akt from phosphatidylinositol 3′-kinase activity in rats
CL Foll, C Corporeau, VL Guen, JP Gouygou, JP Bergé, J Delarue |
American journal of physiology. Endocrinology and metabolism | 2007 |
|
Evaluation of intramyocellular lipid breakdown during exercise by biochemical assay, NMR spectroscopy, and Oil Red O staining
KD Bock, T Dresselaers, B Kiens, EA Richter, PV Hecke, P Hespel |
American journal of physiology. Endocrinology and metabolism | 2007 |
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Inactivity, exercise training and detraining, and plasma lipoproteins. STRRIDE: a randomized, controlled study of exercise intensity and amount
CA Slentz, JA Houmard, JL Johnson, LA Bateman, CJ Tanner, JS McCartney, BD Duscha, WE Kraus |
Journal of applied physiology | 2007 |
|
Cardiovascular Medicine
JT Willerson, HJ Wellens, JN Cohn, DR Holmes |
2007 | |
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Mitochondria
SW Schaffer, MS Suleiman |
2007 | |
|
Adipose Tissue and Adipokines in Health and Disease
G Fantuzzi, T Mazzone |
2007 | |
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Markers of Mitochondrial Biogenesis and Metabolism Are Lower in Overweight and Obese Insulin-Resistant Subjects
LK Heilbronn, SK Gan, N Turner, LV Campbell, DJ Chisholm |
The Journal of clinical endocrinology and metabolism | 2007 |
|
Role of Physical Exercise in Preventing Disease and Improving the Quality of Life
V Stocchi, PD Feo, DA Hood |
2007 | |
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Control of Adipose Triglyceride Lipase Action by Serine 517 of Perilipin A Globally Regulates Protein Kinase A-stimulated Lipolysis in Adipocytes
H Miyoshi, JW Perfield, SC Souza, WJ Shen, HH Zhang, ZS Stancheva, FB Kraemer, MS Obin, AS Greenberg |
The Journal of biological chemistry | 2007 |
|
Insulin resistance and acute coronary syndrome in the young Japanese population have a strong association.
Ikeda N, Nakajima R, Tsunoda T, Nakamura M, Sugi K |
Heart and Vessels | 2007 |
|
Grip strength and the metabolic syndrome: findings from the Hertfordshire Cohort Study.
Sayer AA, Syddall HE, Dennison EM, Martin HJ, Phillips DI, Cooper C, Byrne CD |
QJM : monthly journal of the Association of Physicians | 2007 |
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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylase 1 and 2
David B. Savage, Cheol Soo Choi, Varman T. Samuel, Zhen-Xiang Liu, Dongyan Zhang, Amy Wang, Xian-Man Zhang, Gary W. Cline, Xing Xian Yu, John G. Geisler, Sanjay Bhanot, Brett P. Monia, Gerald I. Shulman |
Journal of Clinical Investigation | 2006 |
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Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
Xueliang Du, Diane Edelstein, Silvana Obici, Ninon Higham, Ming-Hui Zou, and Michael Brownlee |
Journal of Clinical Investigation | 2006 |
|
The Farnesoid X Receptor is Essential for Normal Glucose Homeostasis
Ke Ma, Pradip K. Saha, Lawrence Chan, and David D. Moore |
Journal of Clinical Investigation | 2006 |
|
Critical Role of Stearoyl-CoA Desaturase-1 (SCD1) in the Onset of Diet-induced Hepatic Insulin Resistance
Roger Gutiérrez-Juárez, Alessandro Pocai, Claudia Mulas, Hiraku Ono, Sanjay Bhanot, Brett P. Monia, and Luciano Rossetti |
Journal of Clinical Investigation | 2006 |
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Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism
JP Thyfault, MG Cree, D Zheng, JJ Zwetsloot, EB Tapscott, TR Koves, O Ilkayeva, RR Wolfe, DM Muoio, GL Dohm |
American journal of physiology. Cell physiology | 2006 |
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OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization
NE Wolins, BK Quaynor, JR Skinner, A Tzekov, MA Croce, MC Gropler, V Varma, A Yao-Borengasser, N Rasouli, PA Kern, BN Finck, PE Bickel |
Diabetes | 2006 |
|
Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling
CJ Nolan, JL Leahy, V Delghingaro-Augusto, J Moibi, K Soni, ML Peyot, M Fortier, C Guay, J Lamontagne, A Barbeau, E Przybytkowski, E Joly, P Masiello, S Wang, GA Mitchell, M Prentki |
Diabetologia | 2006 |
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Improvement of Insulin Sensitivity after Peroxisome Proliferator-Activated Receptor-α Agonist Treatment Is Accompanied by Paradoxical Increase of Circulating Resistin Levels
MM Haluzik, Z Lacinova, M Dolinkova, D Haluzikova, D Housa, A Horinek, Z Vernerova, T Kumstyrova, M Haluzik |
Endocrinology | 2006 |
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Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance
CR Vianna, M Huntgeburth, R Coppari, CS Choi, J Lin, S Krauss, G Barbatelli, I Tzameli, YB Kim, S Cinti, GI Shulman, BM Spiegelman, BB Lowell |
Cell Metabolism | 2006 |
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The metabolic syndrome and the heart—: a considered opinion
JG Leichman, VR Lavis, D Aguilar, CR Wilson, H Taegtmeyer |
Clinical Research in Cardiology | 2006 |
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Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
A Tzatsos, KV Kandror |
Molecular and cellular biology | 2006 |
|
Interleukin-1α Inhibits Insulin Signaling with Phosphorylating Insulin Receptor Substrate-1 on Serine Residues in 3T3-L1 Adipocytes
J He, I Usui, K Ishizuka, Y Kanatani, K Hiratani, M Iwata, A Bukhari, T Haruta, T Sasaoka, M Kobayashi |
Molecular Endocrinology | 2006 |
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Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndrome
A Ptitsyn, M Hulver, W Cefalu, D York, SR Smith |
BMC Genomics | 2006 |
|
New Insights into the Pathogenesis of Insulin Resistance in Humans Using Magnetic Resonance Spectroscopy
KF Petersen, GI Shulman |
Obesity | 2006 |
|
Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice
Y Tamura, T Ogihara, T Uchida, F Ikeda, N Kumashiro, T Nomiyama, F Sato, T Hirose, Y Tanaka, H Mochizuki, R Kawamori, H Watada |
Diabetologia | 2006 |
|
Insulin Resistance and Improvements in Signal Transduction
N Musi, LJ Goodyear |
Endocrine | 2006 |
|
AMP-activated protein kinase — the fat controller of the energy railroadThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference
GR Steinberg, SL Macaulay, MA Febbraio, BE Kemp |
Canadian Journal of Physiology and Pharmacology | 2006 |
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FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity
Q Wu, AM Ortegon, B Tsang, H Doege, KR Feingold, A Stahl |
Molecular and cellular biology | 2006 |
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Is all fat the same? The role of fat in the pathogenesis of the metabolic syndrome and type 2 diabetes mellitus
E Hansen, T Hajri, NN Abumrad |
Surgery | 2006 |
|
Enhancing energy and glucose metabolism by disrupting triglyceride synthesis: Lessons from mice lacking DGAT1
HC Chen |
Nutrition & Metabolism | 2006 |
|
Etiology of insulin resistance
KF Petersen, GI Shulman |
The American Journal of Medicine | 2006 |
|
Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men
KF Petersen, S Dufour, J Feng, D Befroy, J Dziura, CD Man, C Cobelli, GI Shulman |
Proceedings of the National Academy of Sciences | 2006 |
|
Third Annual World Congress on the Insulin Resistance Syndrome: Mediators, antecedents, and measurement
ZT Bloomgarden |
Diabetes care | 2006 |
|
Hexosamines, insulin resistance, and the complications of diabetes: current status
MG Buse |
American journal of physiology. Endocrinology and metabolism | 2006 |
|
2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice
Kunihiro Ichinose, Yohei Maeshima, Yoshihiko Yamamoto, Masaru Kinomura, Kumiko Hirokoshi, Hiroyuki Kitayama, Yuki Takazawa, Hitoshi Sugiyama, Yasushi Yamasaki, Naoki Agata, Hirofumi Makino |
Diabetes | 2006 |
|
VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-κB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits
H Roy, S Bhardwaj, M Babu, I Kokina, S Uotila, T Ahtialansaari, T Laitinen, J Hakumaki, M Laakso, KH Herzig, S Ylä-Herttuala |
The FASEB Journal | 2006 |
|
Downregulation of Electron Transport Chain Genes in Visceral Adipose Tissue in Type 2 Diabetes Independent of Obesity and Possibly Involving Tumor Necrosis Factor-
I Dahlman, M Forsgren, A Sjogren, EA Nordstrom, M Kaaman, E Naslund, A Attersand, P Arner |
Diabetes | 2006 |
|
Increased Subcutaneous and Epicardial Adipose Tissue Production of Proinflammatory Cytokines in Cardiac Surgery Patients: Possible Role in Postoperative Insulin Resistance
J Kremen, M Dolinkova, J Krajickova, J Blaha, K Anderlova, Z Lacinova, D Haluzikova, L Bosanska, M Vokurka, S Svacina, M Haluzik |
The Journal of clinical endocrinology and metabolism | 2006 |
|
The Suppressor of Cytokine Signaling 3 Inhibits Leptin Activation of AMP-Kinase in Cultured Skeletal Muscle of Obese Humans
GR Steinberg, AJ McAinch, MB Chen, PE OBrien, JB Dixon, D Cameron-Smith, BE Kemp |
The Journal of clinical endocrinology and metabolism | 2006 |
|
A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. "ARAMIA"
P López-Jaramillo, LP Pradilla, V Lahera, FA Sieger, CF Rueda-Clausen, GA Márquez |
Trials | 2006 |
|
Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
GR Steinberg, BJ Michell, BJ van Denderen, MJ Watt, AL Carey, BC Fam, S Andrikopoulos, J Proietto, CZ Görgün, D Carling, GS Hotamisligil, MA Febbraio, TW Kay, BE Kemp |
Cell Metabolism | 2006 |
|
Specific protein kinase C isoforms as transducers and modulators of insulin signaling
SR Sampson, DR Cooper |
Molecular Genetics and Metabolism | 2006 |
|
Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes
N Tiffin, E Adie, F Turner, HG Brunner, MA van Driel, M Oti, N Lopez-Bigas, C Ouzounis, C Perez-Iratxeta, MA Andrade-Navarro, A Adeyemo, ME Patti, CA Semple, W Hide |
Nucleic Acids Research | 2006 |
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Short-term activation of peroxysome proliferator-activated receptor β/δ increases fatty acid oxidation but does not restore insulin action in muscle cells from type 2 diabetic patients
C Debard, D Cozzone, N Ricard, J Vouillarmet, E Disse, B Husson, M Laville, H Vidal |
Journal of Molecular Medicine | 2006 |
|
Development of type 2 diabetes in children and adolescents
R Weiss, SE Taksali, S Caprio |
Current Diabetes Reports | 2006 |
|
Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects
VB Schrauwen-Hinderling, ME Kooi, MK Hesselink, JA Jeneson, WH Backes, CJ Echteld, JM Engelshoven, M Mensink, P Schrauwen |
Diabetologia | 2006 |
|
The role of AMP-activated protein kinase in mitochondrial biogenesis: AMPK in mitochondrial biogenesis
RM Reznick, GI Shulman |
The Journal of Physiology | 2006 |
|
Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase
G Haemmerle |
Science | 2006 |
|
Effects of chronic Akt activation on glucose uptake in the heart
T Matsui |
American journal of physiology. Endocrinology and metabolism | 2006 |
|
Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction
Morino K, Petersen KF, Shulman GI |
Diabetes | 2006 |
|
Insulin resistance - a common link between type 2 diabetes and cardiovascular disease
HE Lebovitz |
Diabetes, Obesity and Metabolism | 2006 |
|
Peroxisome proliferator-activated receptor gamma as a drug target in the pathogenesis of insulin resistance
L Guo, R Tabrizchi |
Pharmacology & Therapeutics | 2006 |
|
A type IV P-type ATPase affects insulin-mediated glucose uptake in adipose tissue and skeletal muscle in mice
MS Dhar, JS Yuan, SB Elliott, C Sommardahl |
The Journal of Nutritional Biochemistry | 2006 |
|
Obesity-Related Derangements in Metabolic Regulation
DM Muoio, CB Newgard |
Annual Review of Biochemistry | 2006 |
|
Improving the fat content of foods
DI Shaw, WL Hall, CM Williams |
Improving the fat content of foods | 2006 |
|
Diabetic Cardiomyopathy
GC Fonarow, P Srikanthan |
Endocrinology & Metabolism Clinics of North America | 2006 |
|
Pathophysiology of insulin resistance
G Sesti |
Best Practice & Research Clinical Endocrinology & Metabolism | 2006 |
|
Methionine restriction decreases visceral fat mass and preserves insulin action in aging male Fischer 344 rats independent of energy restriction
VL Malloy, RA Krajcik, SJ Bailey, G Hristopoulos, JD Plummer, N Orentreich |
Aging Cell | 2006 |
|
Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes
PD Brown, S Badal, S Morrison, D Ragoobirsingh |
Molecular and Cellular Biochemistry | 2006 |
|
AMP-activated protein kinase: role in metabolism and therapeutic implications
G Schimmack, RA DeFronzo, N Musi |
Diabetes, Obesity and Metabolism | 2006 |
|
Time-dependent effects of fatty acids on skeletal muscle metabolism
SM Hirabara, LR Silveira, F Abdulkader, CR Carvalho, J Procopio, R Curi |
Journal of Cellular Physiology | 2006 |
|
A Lupinoside prevented fatty acid induced inhibition of insulin sensitivity in 3T3 L1 adipocytes
D Dey, BC Pal, T Biswas, SS Roy, A Bandyopadhyay, SK Mandal, BB Giri, S Bhattacharya |
Molecular and Cellular Biochemistry | 2006 |
|
Insulin Resistance and Erectile Dysfunction
SC Kim |
Korean Journal of Urology | 2006 |
|
Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome
D Glintborg, AP Hermann, M Andersen, C Hagen, H Beck-Nielsen, JD Veldhuis, JE Henriksen |
Fertility and Sterility | 2006 |
|
Pancreatic Cancer
J Kleeff, C Michalski, H Friess, MW B??chler |
Pancreas | 2006 |
|
Effect of Skim Milk and Dahi (Yogurt) on Blood Glucose, Insulin, and Lipid Profile in Rats Fed with High Fructose Diet
H Yadav, S Jain, PR Sinha |
Journal of Medicinal Food | 2006 |
|
Involvement of novel PKC isoforms in FFA induced defects in insulin signaling
D Dey, D Basu, SS Roy, A Bandyopadhyay, S Bhattacharya |
Molecular and Cellular Endocrinology | 2006 |
|
Mechanisms linking obesity to insulin resistance and type 2 diabetes
SE Kahn, RL Hull, KM Utzschneider |
Nature | 2006 |
|
Resistin and adiponectin levels in subjects with coronary artery disease and type 2 diabetes
S Yaturu, RP Daberry, J Rains, S Jain |
Cytokine | 2006 |
|
Exercise training and the antioxidant α-lipoic acid in the treatment of insulin resistance and type 2 diabetes
EJ Henriksen |
Free radical biology & medicine | 2006 |
|
The metabolic syndrome: evolving evidence that thiazolidinediones provide rational therapy
KL Wyne |
Diabetes, Obesity and Metabolism | 2006 |
|
The fatty acid transporter FAT/CD36 is upregulated in subcutaneous and visceral adipose tissues in human obesity and type 2 diabetes
A Bonen, NN Tandon, JF Glatz, JJ Luiken, GJ Heigenhauser |
International Journal of Obesity | 2006 |
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Physiological and pathophysiological regulation of regional adipose tissue in the development of insulin resistance and type 2 diabetes
C Rattarasarn |
Acta Physiologica | 2006 |
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Improvement of insulin resistance by miracle fruit (Synsepalum dulcificum) in fructose-rich chow-fed rats
CC Chen, IM Liu, JT Cheng |
Phytotherapy Research | 2006 |
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Different actions of peroxisome proliferator-activated receptors: molecular mechanisms and clinical importance
GD Simonson, DM Kendall |
Current Opinion in Endocrinology & Diabetes | 2006 |
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Palmitate induced lipoapoptosis of exocrine pancreas AR42J cells
Z Landau, E Forti, M Alcaly, RZ Birk |
Apoptosis | 2006 |
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Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle
S Badal, PD Brown, D Ragoobirsingh |
BMC Biochemistry | 2006 |
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Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle
A Chen, B Brar, CS Choi, D Rousso, J Vaughan, Y Kuperman, SN Kim, C Donaldson, SM Smith, P Jamieson, C Li, TR Nagy, GI Shulman, KF Lee, W Vale |
Proceedings of the National Academy of Sciences | 2006 |
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Lipid-lowering drugs
K Pahan |
Cellular and molecular life sciences : CMLS | 2006 |
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Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
G Tuncman, J Hirosumi, G Solinas, L Chang, M Karin, GS Hotamisligil |
Proceedings of the National Academy of Sciences | 2006 |
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Activation of liver X receptors promotes lipid accumulation but does not alter insulin action in human skeletal muscle cells
D Cozzone, C Debard, N Dif, N Ricard, E Disse, J Vouillarmet, R Rabasa-Lhoret, M Laville, D Pruneau, J Rieusset, E Lefai, H Vidal |
Diabetologia | 2006 |
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Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure
H Norrelund, H Wiggers, M Halbirk, J Frystyk, A Flyvbjerg, HE Botker, O Schmitz, JO Jorgensen, JS Christiansen, N Moller |
Journal of Internal Medicine | 2006 |
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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
MJ Watt, N Dzamko, WG Thomas, S Rose-John, M Ernst, D Carling, BE Kemp, MA Febbraio, GR Steinberg |
Nature Medicine | 2006 |
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Metabolic Syndrome: Adenosine Monophosphate-activated Protein Kinase and Malonyl Coenzyme A
NB Ruderman, AK Saha |
Obesity | 2006 |
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New Concepts in Dyslipidemia in the Metabolic Syndrome and Diabetes
MH Davidson, HD Yannicelli |
Metabolic Syndrome and Related Disorders | 2006 |
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Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet
M Fex, MD Nitert, N Wierup, F Sundler, C Ling, H Mulder |
Diabetologia | 2006 |
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Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure
G Florholmen, GH Thoresen, AC Rustan, J Jensen, G Christensen, V Aas |
Diabetologia | 2006 |
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Low-carbohydrate diets: nutritional and physiological aspects
A Adam-Perrot, P Clifton, F Brouns |
Obesity Reviews | 2006 |
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PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes
YS Seo, JH Kim, NY Jo, KM Choi, SH Baik, JJ Park, JS Kim, KS Byun, YT Bak, CH Lee, AR Kim, JE Yeon |
Journal of Gastroenterology and Hepatology | 2006 |
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Skeletal muscle lipid metabolism and the adipomuscular axis
MC Sugden, MJ Holness |
Future Lipidology | 2006 |
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Central Nervous System Regulation of Food Intake
MW Schwartz |
Obesity | 2006 |
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Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases
MC Sugden, MJ Holness |
Archives Of Physiology And Biochemistry | 2006 |
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Intrahepatic insulin resistance in a murine model of steatohepatitis: effect of PPARγ agonist pioglitazone
IA Leclercq, VA Lebrun, P Stärkel, YJ Horsmans |
Laboratory Investigation | 2006 |
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Lipid phosphatases as drug discovery targets for type 2 diabetes
DF Lazar, AR Saltiel |
Nature Reviews Drug Discovery | 2006 |
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Obesity and insulin resistance: is it due to body fat, energy balance, or gut factors?
L Tappy, D DʼAlessio |
Current Opinion in Clinical Nutrition and Metabolic Care | 2006 |
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GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1α
C Lerin, JT Rodgers, DE Kalume, S Kim, A Pandey, P Puigserver |
Cell Metabolism | 2006 |
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Fat uses a TOLL-road to connect inflammation and diabetes
JK Kim |
Cell Metabolism | 2006 |
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Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice
S Sakakibara, T Yamauchi, Y Oshima, Y Tsukamoto, T Kadowaki |
Biochemical and Biophysical Research Communications | 2006 |
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Vitamin E protects the insulin sensitivity and redox balance in rat L6 muscle cells exposed to oxidative stress
RV Moorthi, Z Bobby, N Selvaraj, MG Sridhar |
Clinica Chimica Acta | 2006 |
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Stearoyl-coenzyme A desaturase 1, sterol regulatory element binding protein-1c and peroxisome proliferator-activated receptor-α: independent and interactive roles in the regulation of lipid metabolism
H Sampath, JM Ntambi |
Current Opinion in Clinical Nutrition and Metabolic Care | 2006 |
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Studies on oxidative stress in liver diseases: important future trends in liver research
K Tanikawa, T Torimura |
Medical Molecular Morphology | 2006 |
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Improvement of glycemic control after a 3–5 day insulin infusion in type 2-diabetic patients with insulin resistance can be maintained with glitazone therapy
G Biesenbach, P Grafinger, A Raml |
Wiener klinische Wochenschrift | 2006 |
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Fluoromorphic Substrates for Fatty Acid Metabolism: Highly Sensitive Probes for Mammalian Medium-Chain Acyl-CoA Dehydrogenase
MK Froemming, D Sames |
Angewandte Chemie International Edition | 2006 |
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Metabolic syndrome and risk for Type 2 diabetes
JB Meigs |
Expert Review of Endocrinology & Metabolism | 2006 |
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Intraventricular insulin and leptin decrease sucrose self-administration in rats
DP Figlewicz, JL Bennett, AM Naleid, C Davis, JW Grimm |
Physiology & Behavior | 2006 |
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Effets de la puberté sur la balance glucido-lipidique lors de l’exercice de l’enfant obèse
G Zunquin, D Theunynck, B Sesboüé, P Arhan, D Bouglé |
Applied Physiology, Nutrition, and Metabolism | 2006 |
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Hépatopathie non alcoolique: de la stéatose à la cirrhose
I Leclercq, C Sempoux |
Acta Endoscopica | 2006 |
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Mitochondrial oxidative function and type 2 diabetes
R Rabøl, R Boushel, F Dela |
Applied Physiology, Nutrition, and Metabolism | 2006 |
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Cardiovascular/non–insulin-dependent diabetes mellitus risk factors and intramyocellular lipid in healthy subjects: a sex comparison
LJ White, MA Ferguson, SC McCoy, HW Kim, V Castellano |
Metabolism | 2006 |
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Serum Free Fatty Acids and Glucose Metabolism, Insulin Resistance in Schizophrenia with Chronic Antipsychotics
C Wang, Z Zhang, J Sun, X Zhang, X Mou, X Zhang, X Shang, T Zhang |
Biological Psychiatry | 2006 |
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Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
A Lass, R Zimmermann, G Haemmerle, M Riederer, G Schoiswohl, M Schweiger, P Kienesberger, JG Strauss, G Gorkiewicz, R Zechner |
Cell Metabolism | 2006 |
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Esteatosis hepática y resistencia a la insulina: ¿qué ocurre primero?
E Esteve-Lafuente, W Ricart-Engel |
Clínica e Investigación en Arteriosclerosis | 2006 |
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Beneficial effects of nateglinide on insulin resistance in type 2 diabetes
Y Hazama, M Matsuhisa, K Ohtoshi, S Gorogawa, K Kato, D Kawamori, K Yoshiuchi, Y Nakamura, T Shiraiwa, H Kaneto, Y Yamasaki, M Hori |
Diabetes Research and Clinical Practice | 2006 |
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The role of lipoprotein-associated phospholipase A2 in the metabolic syndrome and diabetes
H Noto, P Chitkara, P Raskin |
Journal of Diabetes and its Complications | 2006 |
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Impaired insulin action despite upregulation of proximal insulin signaling: Novel insights into skeletal muscle insulin resistance in liver cirrhosis
N Jessen, ES Buhl, O Schmitz, S Lund |
Journal of Hepatology | 2006 |
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Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-delta
S Chen, TK Lam, E Park, E Burdett, PY Wang, SR Wiesenthal, L Lam, V Tchipashvili, IG Fantus, A Giacca |
Biochemical and Biophysical Research Communications | 2006 |
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Intramyocellular lipid content in human skeletal muscle
VB Schrauwen-Hinderling, MK Hesselink, P Schrauwen, ME Kooi |
Obesity | 2006 |
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Metabolic Syndrome and Prediabetes
A Babu, L Fogelfeld |
Disease-a-Month | 2006 |
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Réponses neuroendocriniennes au stress et maladies métaboliques
L Tappy |
Nutrition Clinique et Métabolisme | 2006 |
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Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes: Fatty acid activation of AMPK
MJ Watt, GR Steinberg, ZP Chen, BE Kemp, MA Febbraio |
The Journal of Physiology | 2006 |
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Reduced Skeletal Muscle Inhibitor of B Content Is Associated With Insulin Resistance in Subjects With Type 2 Diabetes: Reversal by Exercise Training
A Sriwijitkamol, C Christ-Roberts, R Berria, P Eagan, T Pratipanawatr, RA DeFronzo, LJ Mandarino, N Musi |
Diabetes | 2006 |
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Familial Clustering for Features of the Metabolic Syndrome: The National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study
W Tang, Y Hong, MA Province, SS Rich, PN Hopkins, DK Arnett, JS Pankow, MB Miller, JH Eckfeldt |
Diabetes care | 2006 |
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Adiponectin-Dependent and -Independent Pathways in Insulin-Sensitizing and Antidiabetic Actions of Thiazolidinediones
N Kubota, T Yamauchi, K Tobe, T Kadowaki |
Diabetes | 2006 |
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2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice
Kunihiro Ichinose, Yohei Maeshima, Yoshihiko Yamamoto, Masaru Kinomura, Kumiko Hirokoshi, Hiroyuki Kitayama, Yuki Takazawa, Hitoshi Sugiyama, Yasushi Yamasaki, Naoki Agata, Hirofumi Makino |
Diabetes | 2006 |
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Functional Compensation for Adipose Differentiation-related Protein (ADFP) by Tip47 in an ADFP Null Embryonic Cell Line
C Sztalryd, M Bell, X Lu, P Mertz, S Hickenbottom, BH Chang, L Chan, AR Kimmel, C Londos |
The Journal of biological chemistry | 2006 |
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Glucose metabolism during lactation in a fasting animal, the northern elephant seal
CD Champagne, DS Houser, DE Crocker |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2006 |
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Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1
SY Park, YR Cho, HJ Kim, EG Hong, T Higashimori, SJ Lee, IJ Goldberg, GI Shulman, SM Najjar, JK Kim |
American journal of physiology. Endocrinology and metabolism | 2006 |
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Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction
GD Thakker, NG Frangogiannis, M Bujak, P Zymek, JW Gaubatz, AK Reddy, G Taffet, LH Michael, ML Entman, CM Ballantyne |
American journal of physiology. Heart and circulatory physiology | 2006 |
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Protein-Mediated Fatty Acid Uptake: Novel Insights from In Vivo Models
H Doege, A Stahl |
Physiology (Bethesda, Md.) | 2006 |
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Inverse relationship between PGC-1α protein expression and triacylglycerol accumulation in rodent skeletal muscle
CR Benton, XX Han, M Febbraio, TE Graham, A Bonen |
Journal of applied physiology | 2006 |
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Muscle type-specific fatty acid metabolism in insulin resistance: an integrated in vivo study in Zucker diabetic fatty rats
A Beha, HP Juretschke, J Kuhlmann, C Neumann-Haefelin, U Belz, M Gerl, W Kramer, M Roden, AW Herling |
American journal of physiology. Endocrinology and metabolism | 2006 |
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AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
L Bertrand, A Ginion, C Beauloye, AD Hebert, B Guigas, L Hue, JL Vanoverschelde |
American journal of physiology. Heart and circulatory physiology | 2006 |
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Adipose tissue compensates for defect of phosphatidylinositol 3′-kinase induced in liver and muscle by dietary fish oil in fed rats
C Corporeau, CL Foll, M Taouis, JP Gouygou, JP Bergé, J Delarue |
American journal of physiology. Endocrinology and metabolism | 2006 |
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Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice
AV Hertzel, LA Smith, AH Berg, GW Cline, GI Shulman, PE Scherer, DA Bernlohr |
American journal of physiology. Endocrinology and metabolism | 2006 |
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Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats
EW Kraegen, AK Saha, E Preston, D Wilks, AJ Hoy, GJ Cooney, NB Ruderman |
American journal of physiology. Endocrinology and metabolism | 2006 |
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Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs
A Suryawan, J Escobar, JW Frank, HV Nguyen, TA Davis |
American journal of physiology. Endocrinology and metabolism | 2006 |
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Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity
JG Leichman, D Aguilar, TM King, A Vlada, M Reyes, H Taegtmeyer |
The American journal of clinical nutrition | 2006 |
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n−3 Fatty acids and the metabolic syndrome
YA Carpentier, L Portois, WJ Malaisse |
The American journal of clinical nutrition | 2006 |
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Obesity and the role of adipose tissue in inflammation and metabolism
AS Greenberg, MS Obin |
The American journal of clinical nutrition | 2006 |
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Review: Non-alcoholic fatty liver disease: natural history, pathogenesis and treatment
NC Mcavoy, JW Ferguson, IW Campbell, PC Hayes |
The British Journal of Diabetes & Vascular Disease | 2006 |
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Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes
MJ Gunter, MF Leitzmann |
The Journal of Nutritional Biochemistry | 2006 |
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Biology of Inositols and Phosphoinositides
AL Majumder, BB Biswas |
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Ciliary Neurotrophic Factor Prevents Acute Lipid-Induced Insulin Resistance by Attenuating Ceramide Accumulation and Phosphorylation of c-Jun N-Terminal Kinase in Peripheral Tissues
MJ Watt, A Hevener, GI Lancaster, MA Febbraio |
Endocrinology | 2006 |
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Inhibition of Insulin-Stimulated Glycogen Synthesis by 5-Aminoimidasole-4-Carboxamide-1-β-d-Ribofuranoside-Induced Adenosine 5′-Monophosphate-Activated Protein Kinase Activation: Interactions with Akt, Glycogen Synthase Kinase 3-3α/β, and Glycogen Synthase in Isolated Rat Soleus Muscle
S Fediuc, MP Gaidhu, RB Ceddia |
Endocrinology | 2006 |
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Perilipin Promotes Hormone-sensitive Lipase-mediated Adipocyte Lipolysis via Phosphorylation-dependent and -independent Mechanisms
H Miyoshi, SC Souza, HH Zhang, KJ Strissel, MA Christoffolete, J Kovsan, A Rudich, FB Kraemer, AC Bianco, MS Obin, AS Greenberg |
The Journal of biological chemistry | 2006 |
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Substrate source utilisation in long-term diagnosed type 2 diabetes patients at rest, and during exercise and subsequent recovery
H Boon, EE Blaak, WH Saris, HA Keizer, AJ Wagenmakers, LJ van Loon |
Diabetologia | 2006 |
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Studies on oxidative stress in liver diseases: important future trends in liver research.
Tanikawa K, Torimura T |
Medical Molecular Morphology | 2006 |
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Improvement of glycemic control after a 3-5 day insulin infusion in type 2-diabetic patients with insulin resistance can be maintained with glitazone therapy.
Biesenbach G, Grafinger P, Raml A |
Wiener klinische Wochenschrift | 2006 |
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Decreased expression of adipogenic genes in obese subjects with type 2 diabetes.
Dubois SG, Heilbronn LK, Smith SR, Albu JB, Kelley DE, Ravussin E |
Obesity (Silver Spring, Md.) | 2006 |
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Reduced Mitochondrial Density and Increased IRS-1 Serine Phosphorylation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents
Katsutaro Morino, Kitt Falk Petersen, Sylvie Dufour, Douglas Befroy, Jared Frattini, Nadine Shatzkes, Susanne Neschen, Morris F. White, Stefan Bilz, Saki Sono, Marc Pypaert and Gerald I. Shulman |
Journal of Clinical Investigation | 2005 |
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Dynamic Changes in Fat Oxidation in Human Primary Myocytes Mirror Metabolic Characteristics of the Donor
Barbara Ukropcova Michele McNeil Olga Sereda Lilian Levitan Hui Xie George A. Bray Steven R. Smith |
Journal of Clinical Investigation | 2005 |
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Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance
JK Kim, HJ Kim, SY Park, A Cederberg, R Westergren, D Nilsson, T Higashimori, YR Cho, ZX Liu, J Dong, GW Cline, S Enerback, GI Shulman |
Diabetes | 2005 |
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Inhibition of adipose tissue lipolysis increases intramuscular lipid and glycogen use in vivo in humans
LJ van Loon, M Thomason-Hughes, D Constantin-Teodosiu, R Koopman, PL Greenhaff, DG Hardie, HA Keizer, WH Saris, AJ Wagenmakers |
American journal of physiology. Endocrinology and metabolism | 2005 |
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CYP450, COX-2 and Obesity Related Renal Damage
JD Imig, X Zhao, A Dey, M Shaw |
Toxicology Mechanisms and Methods | 2005 |
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Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism
YB Kim, OD Peroni, WG Aschenbach, Y Minokoshi, K Kotani, A Zisman, CR Kahn, LJ Goodyear, BB Kahn |
Molecular and cellular biology | 2005 |
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Decreased Insulin-Stimulated ATP Synthesis and Phosphate Transport in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents
KF Petersen, S Dufour, GI Shulman |
PLoS Medicine | 2005 |
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Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
K Maeda, H Cao, K Kono, CZ Gorgun, M Furuhashi, KT Uysal, Q Cao, G Atsumi, H Malone, B Krishnan, Y Minokoshi, BB Kahn, RA Parker, GS Hotamisligil |
Cell Metabolism | 2005 |
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Adiponectin and Adiponectin Receptors
T Kadowaki, T Yamauchi |
Endocrine reviews | 2005 |
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Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
TK Lam, A Pocai, R Gutierrez-Juarez, S Obici, J Bryan, L Aguilar-Bryan, GJ Schwartz, L Rossetti |
Nature Medicine | 2005 |
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Prevalence, predisposition and prevention of type II diabetes
D Cheng |
Nutrition & Metabolism | 2005 |
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Fatty acid metabolism is enhanced in type 2 diabetic hearts
AN Carley, DL Severson |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2005 |
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Lipotoxicity in the heart
NM Borradaile, JE Schaffer |
Current Hypertension Reports | 2005 |
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Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes
H Kaneto, T Matsuoka, Y Nakatani, D Kawamori, T Miyatsuka, M Matsuhisa, Y Yamasaki |
Journal of Molecular Medicine | 2005 |
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Heart and liver fatty acid binding proteins and the metabolic syndrome
B Binas |
Current Hypertension Reports | 2005 |
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Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle
DP Koonen, JF Glatz, A Bonen, JJ Luiken |
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids | 2005 |
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Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice
S Neschen, K Morino, LE Hammond, D Zhang, ZX Liu, AJ Romanelli, GW Cline, RL Pongratz, XM Zhang, CS Choi, RA Coleman, GI Shulman |
Cell Metabolism | 2005 |
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Mitochondrial Dysfunction and Type 2 Diabetes
BB Lowell, GI Shulman |
Science | 2005 |
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Increased intramuscular lipid storage in the insulin-resistant and endurance-trained state
LJ van Loon, BH Goodpaster |
Pflügers Archiv - European Journal of Physiology | 2005 |
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Inhibition of adipose tissue lipolysis increases intramuscular lipid use in type 2 diabetic patients
LJ van Loon, RJ Manders, R Koopman, B Kaastra, JH Stegen, AP Gijsen, WH Saris, HA Keizer |
Diabetologia | 2005 |
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Mediating Effects of Inflammatory Biomarkers on Insulin Resistance Associated with Obesity
DJ Wexler, FB Hu, JA Manson, N Rifai, JB Meigs |
Obesity research | 2005 |
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K Imaizumi |
Soy in Health and Disease Prevention | 2005 |
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Methodological approaches to the study of metabolism across individual tissues in man
F Magkos, LS Sidossis |
Current Opinion in Clinical Nutrition and Metabolic Care | 2005 |
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Islet adaptation to insulin resistance: mechanisms and implications for intervention
B Ahren, G Pacini |
Diabetes, Obesity and Metabolism | 2005 |
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Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage
I Raz, R Eldor, S Cernea, E Shafrir |
Diabetes/Metabolism Research and Reviews | 2005 |
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Effect of 2-month detraining on body composition and insulin sensitivity in young female dancers
SY Chen, SM Chen, WH Chang, CH Lai, MC Chen, CH Chou, CH Kuo |
International Journal of Obesity | 2005 |
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R Hoeldtke |
Nutrition and Diabetes | 2005 |
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Stearoyl-CoA desaturase as a new drug target for obesity treatment
A Dobrzyn, JM Ntambi |
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Handbook of Pediatric Obesity
D Gallagher, P Higgins, J Fernández, Q He |
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S Schinner, WA Scherbaum, SR Bornstein, A Barthel |
Diabetic Medicine | 2005 |
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Diagnosis of insulin resistance and associated syndromes: the spectrum from the metabolic syndrome to type 2 diabetes mellitus
GD Simonson, DM Kendall |
Coronary Artery Disease | 2005 |
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Activation of opioid μ-receptors by loperamide to improve interleukin-6-induced inhibition of insulin signals in myoblast C2C12 cells
TF Tzeng, IM Liu, JT Cheng |
Diabetologia | 2005 |
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Molecular mechanisms of lipid-induced insulin resistance in muscle, liver and vasculature
M Krebs, M Roden |
Diabetes, Obesity and Metabolism | 2005 |
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Lipid metabolism in human skeletal muscle cells: effects of palmitate and chronic hyperglycaemia
V Aas, M Rokling-Andersen, AJ Wensaas, GH Thoresen, ET Kase, AC Rustan |
Acta Physiologica Scandinavica | 2005 |
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Fatty acids and insulin resistance in muscle and liver
P Kovacs, M Stumvoll |
Best Practice & Research Clinical Endocrinology & Metabolism | 2005 |
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Consequences of food energy excess and positive energy balance
R Uauy, E Díaz |
Public Health Nutrition | 2005 |
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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
P Gual, YL Marchand-Brustel, JF Tanti |
Biochimie | 2005 |
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IMPROVEMENT OF INSULIN RESISTANCE BY ACANTHOPANAX SENTICOSUS ROOT IN FRUCTOSE-RICH CHOW-FED RATS
TP Liu, CS Lee, SS Liou, IM Liu, JT Cheng |
Clinical and Experimental Pharmacology and Physiology | 2005 |
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Effect of obesity on insulin signaling through JAK2 in rat aorta
HG Zecchin, CT de Souza, PO Prada, JB Carvalheira, LA Velloso, MJ Saad |
Vascular Pharmacology | 2005 |
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A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration
AJ Ruiz-Alcaraz, HK Liu, DJ Cuthbertson, EJ McManus, S Akhtar, C Lipina, AD Morris, JR Petrie, HS Hundal, C Sutherland |
Biochemical Journal | 2005 |
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The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice
C Léon, M Freund, O Latchoumanin, A Farret, P Petit, JP Cazenave, C Gachet |
Purinergic Signalling | 2005 |
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Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3
C Lipina, X Huang, D Finlay, EJ McManus, DR Alessi, C Sutherland |
Biochemical Journal | 2005 |
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Insulin resistance and steatosis in hepatitis C virus infection
A Zekry, JG McHutchison, AM Diehl |
Gut | 2005 |
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Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice
W Oh, L Abu-Elheiga, P Kordari, Z Gu, T Shaikenov, SS Chirala, SJ Wakil |
Proceedings of the National Academy of Sciences | 2005 |
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Hyperthyroidism impairs pancreatic beta cell adaptations to late pregnancy and maternal liporegulation in the rat
MJ Holness, GK Greenwood, ND Smith, MC Sugden |
Diabetologia | 2005 |
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Angiopoietin-related growth factor antagonizes obesity and insulin resistance
Y Oike, M Akao, K Yasunaga, T Yamauchi, T Morisada, Y Ito, T Urano, Y Kimura, Y Kubota, H Maekawa, T Miyamoto, K Miyata, S Matsumoto, J Sakai, N Nakagata, M Takeya, H Koseki, Y Ogawa, T Kadowaki, T Suda |
Nature Medicine | 2005 |
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Insulin resistance: A metabolic pathway to chronic liver disease
E Bugianesi, AJ McCullough, G Marchesini |
Hepatology | 2005 |
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Effect of N-benzoyl-d-phenylalanine and metformin on carbohydrate metabolic enzymes in neonatal streptozotocin diabetic rats
N Ashokkumar, L Pari |
Clinica Chimica Acta | 2005 |
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Mediation of ?-endorphin in exercise-induced improvement in insulin resistance in obese Zucker rats
CF Su, YY Chang, HH Pai, IM Liu, CY Lo, JT Cheng |
Diabetes/Metabolism Research and Reviews | 2005 |
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Link between obesity and type 2 diabetes
A Golay, J Ybarra |
Best Practice & Research Clinical Endocrinology & Metabolism | 2005 |
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Therapy Insight: heart disease and the insulin-resistant patient
SA Cook, T Aitman, RP Naoumova |
Nature Clinical Practice Cardiovascular Medicine | 2005 |
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The JNK pathway as a therapeutic target for diabetes
H Kaneto |
Expert Opinion on Therapeutic Targets | 2005 |
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Proposed Mechanisms for the Induction of Insulin Resistance by Oxidative Stress
A Bloch-Damti, N Bashan |
Antioxidants & Redox Signaling | 2005 |
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Stress and Metabolism
G Seematter, C Binnert, L Tappy |
Metabolic Syndrome and Related Disorders | 2005 |
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ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells
Y Izawa, M Yoshizumi, Y Fujita, N Ali, Y Kanematsu, K Ishizawa, K Tsuchiya, T Obata, Y Ebina, S Tomita, T Tamaki |
Experimental Cell Research | 2005 |
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A potential link between muscle peroxisome proliferator- activated receptor-α signaling and obesity-related diabetes
BN Finck, C Bernal-Mizrachi, DH Han, T Coleman, N Sambandam, LL LaRiviere, JO Holloszy, CF Semenkovich, DP Kelly |
Cell Metabolism | 2005 |
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Effects of fenofibrate and insulin on the biosynthesis of unsaturated fatty acids in streptozotocin diabetic rats
MA Montanaro, AM Bernasconi, MS González, OJ Rimoldi, RR Brenner |
Prostaglandins, Leukotrienes and Essential Fatty Acids | 2005 |
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Type 2 diabetes: principles of pathogenesis and therapy
M Stumvoll, BJ Goldstein, TW van Haeften |
The Lancet | 2005 |
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Age and muscle-type modulated role of intramyocellular lipids in the progression of insulin resistance in nondiabetic Zucker rats
M Korach-André, J Gounarides, R Deacon, M Beil, D Sun, J Gao, D Laurent |
Metabolism | 2005 |
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HIV antiretroviral treatment alters adipokine expression and insulin sensitivity of adipose tissue in vitro and in vivo
C Lagathu, M Kim, M Maachi, C Vigouroux, P Cervera, J Capeau, M Caron, JP Bastard |
Biochimie | 2005 |
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Olanzapine impairs glycogen synthesis and insulin signaling in L6 skeletal muscle cells
J Engl, M Laimer, A Niederwanger, M Kranebitter, M Starzinger, MT Pedrini, WW Fleischhacker, JR Patsch, CF Ebenbichler |
Molecular Psychiatry | 2005 |
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The role of stearoyl-CoA desaturase in the control of metabolism
A Dobrzyn, JM Ntambi |
Prostaglandins, Leukotrienes and Essential Fatty Acids | 2005 |
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Review article: the treatment of non-alcoholic steatohepatitis with thiazolidinediones
H Reynaert, A Geerts, J Henrion |
Alimentary Pharmacology and Therapeutics | 2005 |
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Endothelial function, insulin action and cardiovascular risk factors in young healthy adult offspring of parents with Type 2 diabetes: effect of vitamin E in a randomized double-blind, controlled clinical trial
PT McSorley, PM Bell, IS Young, AB Atkinson, B Sheridan, JP Fee, DR McCance |
Diabetic Medicine | 2005 |
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Obesity in pediatric oncology
PC Rogers, LR Meacham, KC Oeffinger, DW Henry, BJ Lange |
Pediatric Blood & Cancer | 2005 |
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Review article: hepatic steatosis and insulin resistance
A Lonardo, S Lombardini, M Ricchi, F Scaglioni, P Loria |
Alimentary Pharmacology and Therapeutics | 2005 |
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Effect of Divalproex on Metabolic Parameters Is Dose Related in Migraine Prophylaxis
MW Green, S Giordano, P Jiang, M Jafari, TB Smith |
Headache: The Journal of Head and Face Pain | 2005 |
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High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice
AC Heijboer, PJ Voshol, E Donga, CG Eden, LM Havekes, JA Romijn, H Pijl, EP Corssmit |
Peptides | 2005 |
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Disturbances of glucose and lipid metabolism during treatment with new generation antipsychotics
MA Rettenbacher |
Current Opinion in Psychiatry | 2005 |
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Effect of troglitazone on the desaturases in a rat model of insulin-resistance induced by a sucrose-rich diet
MA Montanaro, YB Lombardo, MS González, AM Bernasconi, A Chicco, OJ Rimoldi, JC Basabe, RR Brenner |
Prostaglandins, Leukotrienes and Essential Fatty Acids | 2005 |
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EFFECT OF TETRAHYDROCURCUMIN ON BLOOD GLUCOSE, PLASMA INSULIN AND HEPATIC KEY ENZYMES IN STREPTOZOTOCIN INDUCED DIABETIC RATS
L Pari, P Murugan |
Journal of Basic and Clinical Physiology and Pharmacology | 2005 |
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The metabolic role of growth hormone in humans with particular reference to fasting
H Nørrelund |
Growth Hormone & IGF Research | 2005 |
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Insulin and HOMA in Spanish prepubertal children: Relationship with lipid profile
C Garcés, B Cano, JJ Granizo, M Benavente, E Viturro, J Gutiérrez-Guisado, I Oya, MA Lasunción, M Oya |
Clinical Biochemistry | 2005 |
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International Review of Neurobiology
ZT Bloomgarden |
International review of neurobiology | 2005 |
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Mechanisms of Disease: pathway-selective insulin resistance and microvascular complications of diabetes
PH Groop, C Forsblom, MC Thomas |
Nature Clinical Practice Endocrinology & Metabolism | 2005 |
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Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats
H Satoh, MT Nguyen, M Trujillo, T Imamura, I Usui, PE Scherer, JM Olefsky |
Diabetes | 2005 |
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Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver
SY Park, YR Cho, BN Finck, HJ Kim, T Higashimori, EG Hong, MK Lee, C Danton, S Deshmukh, GW Cline, JJ Wu, AM Bennett, B Rothermel, A Kalinowski, KS Russell, YB Kim, DP Kelly, JK Kim |
Diabetes | 2005 |
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Stearoyl-CoA desaturase: A therapeutic target of insulin resistance and diabetes
A Dobrzyn, J Ntambi |
Drug Discovery Today: Therapeutic Strategies | 2005 |
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Données nouvelles sur les récepteurs PPAR
H Vidal |
Annales d'Endocrinologie | 2005 |
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Inhibition of cellular responses to insulin in a rat liver cell line. A role for PKC in insulin resistance: Insulin resistance and Cl − channels
L Puljak, MJ Pagliassotti, Y Wei, I Qadri, V Parameswara, V Esser, JG Fitz, G Kilic |
The Journal of Physiology | 2005 |
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Reversal of Nonalcoholic Hepatic Steatosis, Hepatic Insulin Resistance, and Hyperglycemia by Moderate Weight Reduction in Patients With Type 2 Diabetes
KF Petersen, S Dufour, D Befroy, M Lehrke, RE Hendler, GI Shulman |
Diabetes | 2005 |
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Nonesterified fatty acids as mediators of glucose intolerance in Indian Asian populations
Jeetesh V Patel, Avni Vyas, Dorairaj Prabhakaran, Deepak Bhatnagar, Paul N Durrington, Adrien Heald, Elizabeth A Hughes, Michael I Mackness, K Srinath Reddy, J Kennedy Cruickshank |
Diabetes care | 2005 |
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Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide
Jose M Cacicedo, Sunun Benjachareowong, Eva Chou, Neil B Ruderman, Yasuo Ido |
Diabetes | 2005 |
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Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study
Håkan K R Karlsson, Kirsti Hällsten, Marie Björnholm, Hiroki Tsuchida, Alexander V Chibalin, Kirsi A Virtanen, Olli J Heinonen, Fredrik Lönnqvist, Pirjo Nuutila, Juleen R Zierath |
Diabetes | 2005 |
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Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men
David Faeh, Kaori Minehira, Jean-Marc Schwarz, Raj Periasamy, Raj Periasami, Seongsu Park, Park Seongsu, Luc Tappy |
Diabetes | 2005 |
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Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients
Mandeep Bajaj, Swangjit Suraamornkul, Anthony Romanelli, Gary W Cline, Lawrence J Mandarino, Gerald I Shulman, Ralph A DeFronzo |
Diabetes | 2005 |
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Divergent effects of rosiglitazone on protein-mediated fatty acid uptake in adipose and in muscle tissues of Zucker rats
SL Coort, WA Coumans, A Bonen, GJ van der Vusse, JF Glatz, JJ Luiken |
Journal of lipid research | 2005 |
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Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 diabetes?
CR Triggle, A Howarth, ZJ Cheng, H Ding |
Canadian Journal of Physiology and Pharmacology | 2005 |
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PPARγ-mediated insulin sensitization: the importance of fat versus muscle
U Kintscher, RE Law |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Postexercise insulin sensitivity is not impaired after an overnight lipid infusion
S Schenk, JN Cook, AE Kaufman, JF Horowitz |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes
B Ravikumar, PE Carey, JE Snaar, DK Deelchand, DB Cook, RD Neely, PT English, MJ Firbank, PG Morris, R Taylor |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Relationship between visceral adiposity and intramyocellular lipid content in two rat models of insulin resistance
M Korach-André, J Gao, JS Gounarides, R Deacon, A Islam, D Laurent |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes
TM Lewin, S Wang, CA Nagle, CG van Horn, RA Coleman |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Branched-chain amino acids improve glucose metabolism in rats with liver cirrhosis
S Nishitani, K Takehana, S Fujitani, I Sonaka |
AJP Gastrointestinal and Liver Physiology | 2005 |
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Simulated first-phase insulin release using Humulin or insulin analog HIM2 is associated with prolonged improvement in postprandial glycemia
CA DiCostanzo, MC Moore, M Lautz, M Scott, B Farmer, CA Everett, JG Still, A Higgins, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 2005 |
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Atherosclerosis: Diet and Drugs
A von Eckardstein |
2005 | |
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Diabetes und Herz
T Meinertz, P Rösen, D Ziegler, A Schömig, D Tschöpe |
2005 | |
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Inhibition of Insulin Receptor Gene Expression and Insulin Signaling by Fatty Acid: Interplay of PKC Isoforms Therein
D Dey, M Mukherjee, D Basu, M Datta, SS Roy, A Bandyopadhyay, S Bhattacharya |
Cellular Physiology and Biochemistry | 2005 |
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Free Fatty Acid-Induced Insulin Resistance in the Obese Is Not Prevented by Rosiglitazone Treatment
S Dhindsa, D Tripathy, N Sanalkumar, S Ravishankar, H Ghanim, A Aljada, P Dandona |
The Journal of clinical endocrinology and metabolism | 2005 |
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Diabetes, Obesity, and the Brain
MW Schwartz, D Porte |
Science | 2005 |
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LC/MS/MS Method for Quantitative Determination of Long-Chain Fatty Acyl-CoAs
C Magnes, FM Sinner, W Regittnig, TR Pieber |
Analytical Chemistry | 2005 |
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Dysregulation of IRS2 in beta cells and brain causes obesity and diabetes
Xueying Lin, Akiko Taguchi, Sunmin Park, Jake A. Kushner, Fan Li, Yedan Li, Morris F. White |
Journal of Clinical Investigation | 2004 |
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Insulin receptor substrate-2 plays a crucial role in b cells and the hypothalamus
Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, Wataru Yano, Ryo Suzuki, Kohjiro Ueki, Iseki Takamoto, Hidemi Satoh, Toshiyuki Maki, Tetsuya Kubota, Masao Moroi, Miki Okada-Iwabu, Osamu Ezaki, Ryozo Nagai, Yoichi Ueta, Takashi Kadowaki, and Tetsuo Noda |
Journal of Clinical Investigation | 2004 |
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PKC-theta Knockout Mice Are Protected from Fat-Induced Insulin Resistance
Jason K. Kim, Jonathan J. Fillmore, Mary Jean Sunshine, Bjoern Albrecht, Takamasa Higashimori, Dong-Wook Kim, Zhen-Xiang Liu, Timothy J. Soos, Gary Cline, William R. O'Brien, Dan R. Littman, Gerald I. Shulman |
Journal of Clinical Investigation | 2004 |
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Site and Mechanism of Leptin Action in a Rodent Form of Congenital Lipodystrophy
Esra Asilmaz, Paul Cohen, Makoto Miyazaki, Pawel Dobrzyn, Kohjiro Ueki, Gulnorakhon Fayzikhodjaeva, Alexander A. Soukas, C. Ronald Kahn, James M. Ntambi, Nicholas D. Socci, Jeffrey M. Friedman |
Journal of Clinical Investigation | 2004 |
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Inactivation of Fatty Acid Transport Protein 1 Prevents Fat-Induced Insulin Resistance In Skeletal Muscle
Jason K. Kim, Ruth E. Gimeno, Takamasa Higashimori, Hyo-Jeong Kim, Hyejeong Choi, Sandhya Punreddy, David J. Hirsch, Robin L. Mozell, Guo Tan, Alain Stricker-Krongrad, Jonathan J. Fillmore, Zhen-Xiang Liu, Jianying Dong, Gary Cline, Andreas Stahl, Harvey F. Lodish, Gerald I. Shulman |
Journal of Clinical Investigation | 2004 |
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Adenoviral-Mediated Chronic Hyperresistinemia Leads to In vivo Insulin Resistance In Normal Rats
Hiroaki Satoh, M.T. Audrey Nguyen, Philip D.G. Miles, Takeshi Imamura, Isao Usui, and Jerrold M. Olefsky |
Journal of Clinical Investigation | 2004 |
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GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization
Ko Kotani, Odile D. Peroni1, Yasuhiko Minokoshi, Olivier Boss, Barbara B. Kahn |
Journal of Clinical Investigation | 2004 |
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Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle
M Straczkowski, I Kowalska, A Nikolajuk, S Dzienis-Straczkowska, I Kinalska, M Baranowski, M Zendzian-Piotrowska, Z Brzezinska, J Gorski |
Diabetes | 2004 |
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Moderate caloric restriction, but not physiological hyperleptinemia per se, enhances mitochondrial oxidative capacity in rat liver and skeletal muscle--tissue-specific impact on tissue triglyceride content and AKT activation
R Barazzoni, M Zanetti, A Bosutti, G Biolo, L Vitali-Serdoz, M Stebel, G Guarnieri |
Endocrinology | 2004 |
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Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
VB Ritov, EV Menshikova, J He, RE Ferrell, BH Goodpaster, DE Kelley |
Diabetes | 2004 |
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Muscle-specific overexpression of CD36 reverses the insulin resistance and diabetes of MKR mice
L Héron-Milhavet, M Haluzik, S Yakar, O Gavrilova, S Pack, WC Jou, A Ibrahimi, H Kim, D Hunt, D Yau, Z Asghar, J Joseph, MB Wheeler, NA Abumrad, D LeRoith |
Endocrinology | 2004 |
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Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36
A Bonen, ML Parolin, GR Steinberg, J Calles-Escandon, NN Tandon, JF Glatz, JJ Luiken, GJ Heigenhauser, DJ Dyck |
The FASEB Journal | 2004 |
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Genetic Background (C57BL/6J Versus FVB/N) Strongly Influences the Severity of Diabetes and Insulin Resistance in ob/ob Mice
M Haluzik, C Colombo, O Gavrilova, S Chua, N Wolf, M Chen, B Stannard, KR Dietz, DL Roith, ML Reitman |
Endocrinology | 2004 |
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Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus
L Heilbronn, SR Smith, E Ravussin |
International Journal of Obesity | 2004 |
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Role of calpains in diabetes mellitus: A mini review
F Harris, L Chatfield, J Singh, DA Phoenix |
Molecular and Cellular Biochemistry | 2004 |
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Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor gamma (PPARgamma), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo
G Jiang, Q Dallas-Yang, S Biswas, Z Li, BB Zhang |
Biochemical Journal | 2004 |
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The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes
C Bouché, S Serdy, CR Kahn, AB Goldfine |
Endocrine reviews | 2004 |
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Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
J An, DM Muoio, M Shiota, Y Fujimoto, GW Cline, GI Shulman, TR Koves, R Stevens, D Millington, CB Newgard |
Nature Medicine | 2004 |
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Glucose Homeostasis and Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred Strains of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1
HJ Goren, RN Kulkarni, CR Kahn |
Endocrinology | 2004 |
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Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells
RB Ceddia, R Somwar, A Maida, X Fang, G Bikopoulos, G Sweeney |
Diabetologia | 2004 |
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Decreased Plasma Adiponectin Concentrations Are Closely Related to Hepatic Fat Content and Hepatic Insulin Resistance in Pioglitazone-Treated Type 2 Diabetic Patients
M Bajaj, S Suraamornkul, P Piper, LJ Hardies, L Glass, E Cersosimo, T Pratipanawatr, Y Miyazaki, RA DeFronzo |
The Journal of clinical endocrinology and metabolism | 2004 |
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Lipid-Induced Insulin Resistance in the Liver: Role of Exercise
CS Katsanos |
Sports Medicine | 2004 |
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The Role of Lipid Accumulation in Liver and Muscle for Insulin Resistance and Type 2 Diabetes Mellitus in Humans
M Krssak, M Roden |
Reviews in Endocrine and Metabolic Disorders | 2004 |
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Ghrelin regulates mitochondrial-lipid metabolism gene expression and tissue fat distribution in liver and skeletal muscle
R Barazzoni, A Bosutti, M Stebel, MR Cattin, E Roder, L Visintin, L Cattin, G Biolo, M Zanetti, G Guarnieri |
American journal of physiology. Endocrinology and metabolism | 2004 |
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Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
K Ueki, T Kondo, YH Tseng, CR Kahn |
Proceedings of the National Academy of Sciences | 2004 |
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Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of Type 2 diabetic patients
C Debard, M Laville, V Berbe, E Loizon, C Guillet, B Morio-Liondore, Y Boirie, H Vidal |
Diabetologia | 2004 |
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Pathophysiology and Long-Term Management of the Metabolic Syndrome
FX Pi-Sunyer |
Obesity research | 2004 |
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IRS2 takes center stage in the development of type 2 diabetes
MJ Brady |
Journal of Clinical Investigation | 2004 |
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Growth Hormone and Glucose Homeostasis
JO Jørgensen, M Krag, N Jessen, H Nørrelund, ET Vestergaard, N Møller, JS Christiansen |
Hormone Research | 2004 |
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Insulin resistance and changes in plasma concentration of TNFalpha, IGF1, and NEFA in dogs during weight gain and obesity
C Gayet, E Bailhache, H Dumon, L Martin, B Siliart, P Nguyen |
Journal of Animal Physiology and Animal Nutrition | 2004 |
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Intramyocellular lipids and insulin resistance
J Machann, H Haring, F Schick, M Stumvoll |
Diabetes, Obesity and Metabolism | 2004 |
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What is the contribution of obesity to the metabolic syndrome?
SM Grundy |
Endocrinology & Metabolism Clinics of North America | 2004 |
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AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome
N Ruderman, M Prentki |
Nature Reviews Drug Discovery | 2004 |
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Pharmacotherapy of Obesity
FX Pi–Sunyer |
Pharmacotherapy of Obesity | 2004 |
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The molecular mechanism linking muscle fat accumulation to insulin resistance
MW Hulver, GL Dohm |
Proceedings of the Nutrition Society | 2004 |
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Assessment of the influence of fatty acids on indices of insulin sensitivity and myocellular lipid content by use of magnetic resonance spectroscopy in cats
C Wilkins, RC Long, M Waldron, DC Ferguson, M Hoenig |
American Journal of Veterinary Research | 2004 |
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Lipolytic PPAR activation: new insights into the intersection of triglycerides and inflammation?
O Ziouzenkova, J Plutzky |
Current Opinion in Clinical Nutrition and Metabolic Care | 2004 |
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Peroxisome Proliferator Activator Receptors (PPAR), Insulin Resistance, and Cardiomyopathy
LA Nikolaidis, TB Levine |
Cardiology in Review | 2004 |
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A family of Acrp30/adiponectin structural and functional paralogs
GW Wong, J Wang, C Hug, TS Tsao, HF Lodish |
Proceedings of the National Academy of Sciences | 2004 |
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Encyclopedia of Biological Chemistry
S DiMauro |
Encyclopedia of Biological Chemistry | 2004 |
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Diabetes in African Americans: Unique pathophysiologic features
MA Banerji |
Current Diabetes Reports | 2004 |
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Targeting Insulin Resistance and β-Cell Dysfunction: The Role of Thiazolidinediones
SD Prato, P Marchetti |
Diabetes Technology & Therapeutics | 2004 |
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Insulin receptor substrate proteins and diabetes
YH Lee, MF White |
Archives of Pharmacal Research | 2004 |
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Prevention of Cardiovascular Complications of Diabetes Mellitus by Aspirin
C Nobles-James, EA James, JR Sowers |
Cardiovascular Drug Reviews | 2004 |
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Obesity and the metabolic syndrome: implications for dietetics practitioners
GA Bray, CM Champagne |
Journal of the American Dietetic Association | 2004 |
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Genetically modified mouse models for disorders of fatty acid metabolism:
PA Wood |
Nutrition | 2004 |
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Age- and sex-related reference values for serum insulin concentration and its biological determinants in a French healthy population. The STANISLAS cohort
A Francois, S Maumus, M Vincent-Viry, R Guéguen, G Siest, S Visvikis |
Clinical Chemistry and Laboratory Medicine | 2004 |
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Management of Type 2 Diabetes Mellitus: Is It Time for a Paradigm Shift?
KL Wyne |
Metabolic Syndrome and Related Disorders | 2004 |
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Peroxisomal fatty acid metabolism, peroxisomal proliferator-activated receptors and non-alcoholic fatty liver disease
GA Macdonald, JB Prins |
Journal of Gastroenterology and Hepatology | 2004 |
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Correlations of adiponectin level with insulin resistance and atherosclerosis in Japanese male populations
K Higashiura, N Ura, J Ohata, N Togashi, S Takagi, S Saitoh, H Murakami, Y Takagawa, K Shimamoto |
Clinical Endocrinology | 2004 |
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The metabolic phenotype of pre-diabetes in obese youth
S Caprio, R Weiss |
Nutrition, Metabolism and Cardiovascular Diseases | 2004 |
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Intramyocellular triacylglycerol as a substrate source during exercise
LJ van Loon |
Proceedings of the Nutrition Society | 2004 |
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Leptin: linking adipocyte metabolism with cardiovascular and autoimmune diseases
F Peelman, W Waelput, H Iserentant, D Lavens, S Eyckerman, L Zabeau, J Tavernier |
Progress in Lipid Research | 2004 |
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A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus
J Seufert, G Lübben, K Dietrich, PC Bates |
Clinical Therapeutics | 2004 |
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Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat–fed rats
JS Choi, MH Jung, HS Park, J Song |
Nutrition | 2004 |
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Obesity prevention in children: physical activity and nutrition
MS Sothern |
Nutrition | 2004 |
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Síndrome metabólico
FC Murillo, E Meriño-Ibarra, JM Duarte, JA López-Oliva |
Medicine - Programa de Formación Médica Continuada Acreditado | 2004 |
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Differential effects of metformin and exercise on muscle adiposity and metabolic indices in human immunodeficiency virus-infected patients
SD Driscoll, GE Meininger, K Ljungquist, C Hadigan, M Torriani, A Klibanski, WR Frontera, S Grinspoon |
The Journal of clinical endocrinology and metabolism | 2004 |
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Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters
JJ Luiken, SL Coort, DP Koonen, DJ van der Horst, A Bonen, A Zorzano, JF Glatz |
Pflügers Archiv - European Journal of Physiology | 2004 |
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PPARs and the complex journey to obesity
RM Evans, GD Barish, YX Wang |
Nature Medicine | 2004 |
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Thiazolidinediones et insulino-sensibilité : rôle du récepteur nucléaire PPARγ
JP Pégorier, J Girard |
Annales d'Endocrinologie | 2004 |
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Non-alcoholic steatohepatitis: review of a growing medical problem
K Sligte, I Bourass, JP Sels, A Driessen, RW Stockbrűgger, GH Koek |
European Journal of Internal Medicine | 2004 |
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Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling
JF Tanti, P Gual, T Grémeaux, T Gonzalez, R Barrès, YL Marchand-Brustel |
Annales d'Endocrinologie | 2004 |
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Insulin resistance and vascular disease
FJ Maritz |
Journal of Endocrinology, Metabolism and Diabetes of South Africa | 2004 |
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Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats
SL Coort, DM Hasselbaink, DP Koonen, J Willems, WA Coumans, A Chabowski, GJ van der Vusse, A Bonen, JF Glatz, JJ Luiken |
Diabetes | 2004 |
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Inhibition of Insulin Sensitivity by Free Fatty Acids Requires Activation of Multiple Serine Kinases in 3T3-L1 Adipocytes
Z Gao, X Zhang, A Zuberi, D Hwang, MJ Quon, M Lefevre, J Ye |
Molecular Endocrinology | 2004 |
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The 1st World Congress on the Insulin Resistance Syndrome
Zachary T Bloomgarden |
Diabetes care | 2004 |
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Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1
Hubert C Chen, Meghana Rao, Mini P Sajan, Mary Standaert, Yoshinori Kanoh, Atsushi Miura, Robert V Farese Jr, Robert V Farese |
Diabetes | 2004 |
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CD36 in myocytes channels fatty acids to a lipase-accessible triglyceride pool that is related to cell lipid and insulin responsiveness
Claire C Bastie, Tahar Hajri, Victor A Drover, Paul A Grimaldi, Nada A Abumrad |
Diabetes | 2004 |
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Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin: clinical pathophysiology and natural history of beta-cell dysfunction and insulin resistance
Franck Mauvais-Jarvis, Eugène Sobngwi, Raphaël Porcher, Jean-Pierre Riveline, Jean-Philippe Kevorkian, Christian Vaisse, Guillaume Charpentier, Pierre-Jean Guillausseau, Patrick Vexiau, Jean-François Gautier |
Diabetes | 2004 |
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The role of acyl‐CoA:diacylglycerol acyltransferase (DGAT) in energy metabolism
YH Yu, H Ginsberg |
Annals of Medicine | 2004 |
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Understanding insulin resistance: What are the clinical implications?
WI Sivitz |
Postgraduate Medicine | 2004 |
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WY-14643 and 9-cis-retinoic acid induce IRS-2/PI 3-kinase signalling pathway and increase glucose transport in human skeletal muscle cells: differential effect in myotubes from healthy subjects and Type 2 diabetic patients
K Bouzakri, M Roques, C Debard, V Berbe, J Rieusset, M Laville, H Vidal |
Diabetologia | 2004 |
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Modulation of the JNK Pathway in Liver Affects Insulin Resistance Status
Y Nakatani, H Kaneto, D Kawamori, M Hatazaki, T Miyatsuka, T Matsuoka, Y Kajimoto, M Matsuhisa, Y Yamasaki, M Hori |
The Journal of biological chemistry | 2004 |
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Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice
AC Heijboer, E Donga, PJ Voshol, ZC Dang, LM Havekes, JA Romijn, EP Corssmit |
Journal of lipid research | 2004 |
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Fat storage in pancreas and in insulin-sensitive tissues in pathogenesis of type 2 diabetes
F Assimacopoulos-Jeannet |
International Journal of Obesity | 2004 |
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Inhibitor κB kinase is involved in the paracrine crosstalk between human fat and muscle cells
D Dietze, S Ramrath, O Ritzeler, N Tennagels, H Hauner, J Eckel |
International Journal of Obesity | 2004 |
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Unraveling the Cellular Mechanism of Insulin Resistance in Humans: New Insights from Magnetic Resonance Spectroscopy
GI Shulman |
Physiology (Bethesda, Md.) | 2004 |
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Nonacute effects of H-FABP deficiency on skeletal muscle glucose uptake in vitro
E Erol, GW Cline, JK Kim, H Taegtmeyer, B Binas |
American journal of physiology. Endocrinology and metabolism | 2004 |
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How Free Fatty Acids Inhibit Glucose Utilization in Human Skeletal Muscle
M Roden |
Physiology (Bethesda, Md.) | 2004 |
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Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes
LJ van Loon, R Koopman, R Manders, W der Weegen, GP van Kranenburg, HA Keizer |
American journal of physiology. Endocrinology and metabolism | 2004 |
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Tetrahydrobiopterin increases insulin sensitivity in patients with type 2 diabetes and coronary heart disease
T Nyström, A Nygren, Å Sjöholm |
American journal of physiology. Endocrinology and metabolism | 2004 |
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Use of intramuscular triacylglycerol as a substrate source during exercise in humans
LJ van Loon |
Journal of applied physiology | 2004 |
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Tamoxifen induced hepatotoxicity in breast cancer patients with pre-existing liver steatosis: the role of glucose intolerance
IS Elefsiniotis, KD Pantazis, A Ilias, L Pallis, A Mariolis, I Glynou, H Kada, A Moulakakis |
European Journal of Gastroenterology & Hepatology | 2004 |
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Leptin and the Control of Metabolism: Role for Stearoyl-CoA Desaturase-1 (SCD-1)
P Cohen, JM Friedman |
The Journal of nutrition | 2004 |
|
Ingestion of Guar Gum Hydrolysate, a Soluble and Fermentable Nondigestible Saccharide, Improves Glucose Intolerance and Prevents Hypertriglyceridemia in Rats Fed Fructose
T Suzuki, H Hara |
The Journal of nutrition | 2004 |
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Postabsorptive and insulin-stimulated energy and protein metabolism in patients with myotonic dystrophy type 1
G Perseghin, M Comola, P Scifo, S Benedini, FD Cobelli, R Lanzi, F Costantino, G Lattuada, A Battezzati, AD Maschio, L Luzi |
The American journal of clinical nutrition | 2004 |
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Dietary lipids and gene expression
HM Roche |
Biochemical Society Transactions | 2004 |
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In Vitro Phosphorylation of Insulin Receptor Substrate 1 by Protein Kinase C-ζ: Functional Analysis and Identification of Novel Phosphorylation Sites
MR Sommerfeld, S Metzger, M Stosik, N Tennagels, J Eckel |
Biochemistry | 2004 |
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Peroxisome Proliferator-Activated Receptor (PPAR) Activation Induces Tissue-Specific Effects on Fatty Acid Uptake and Metabolism in Vivo—A Study Using the Novel PPARα/γ Agonist Tesaglitazar
BD Hegarty, SM Furler, ND Oakes, EW Kraegen, GJ Cooney |
Endocrinology | 2004 |
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Rosiglitazone Enhances Glucose Tolerance by Mechanisms Other than Reduction of Fatty Acid Accumulation within Skeletal Muscle
SJ Lessard, SL Giudice, W Lau, JJ Reid, N Turner, MA Febbraio, JA Hawley, MJ Watt |
Endocrinology | 2004 |
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Alterations of Glucose Metabolism in Type 2 Diabetes Mellitus. An Overview
RC Bonadonna |
Reviews in Endocrine and Metabolic Disorders | 2004 |
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Up-regulation of insulin receptor substrate-2 in pancreatic beta-cells prevents diabetes
Anita M. Hennige, Deborah J. Burks, Umut Ozcan, Rohit N. Kulkarni, Jing Ye, Sunmin Park, Markus Schubert, Tracey L. Fisher, Matt A. Dow, Rebecca Leshan, Mark Zakaria, Mahmud Mossa-Basha, Morris F. White |
Journal of Clinical Investigation | 2003 |
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Chronic Inflammation in Fat Plays a Crucial Role in the Development of Obesity-Related Insulin Resistance
Haiyan Xu, Glenn T. Barnes, Qing Yang , Guo Tan, Daseng Yang, Jason Chou, Jason Sole, Jeffrey S. Ross, Andrew Nichols, Louis A. Tartaglia, Hong Chen |
Journal of Clinical Investigation | 2003 |
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Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells
M Artwohl, M Roden, W Waldhäusl, A Freudenthaler, SM Baumgartner-Parzer |
The FASEB Journal | 2003 |
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Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma
DB Savage, GD Tan, CL Acerini, SA Jebb, M Agostini, M Gurnell, RL Williams, AM Umpleby, EL Thomas, JD Bell, AK Dixon, F Dunne, R Boiani, S Cinti, A Vidal-Puig, F Karpe, VK Chatterjee, S O'Rahilly |
Diabetes | 2003 |
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Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger, X Han, SE Lewis, S Cases, RV Farese, DS Ory, JE Schaffer |
Proceedings of the National Academy of Sciences | 2003 |
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MAP kinases and mTOR mediate insulin-induced phosphorylation of Insulin Receptor Substrate-1 on serine residues 307, 612 and 632
P Gual, T Grémeaux, T Gonzalez, YL Marchand-Brustel, JF Tanti |
Diabetologia | 2003 |
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Resistin: molecular history and prognosis
RR Banerjee, MA Lazar |
Journal of Molecular Medicine | 2003 |
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Lipotoxicity: when tissues overeat:
JE Schaffer |
2003 | |
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Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
KF Petersen, D Befroy, S Dufour, J Dziura, C Ariyan, DL Rothman, L DiPietro, GW Cline, GI Shulman |
Science | 2003 |
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Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex
M Cnop, PJ Havel, KM Utzschneider, DB Carr, MK Sinha, EJ Boyko, BM Retzlaff, RH Knopp, JD Brunzell, SE Kahn |
Diabetologia | 2003 |
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Relationship between Serum Leptin Concentration and Low-Density Muscle in Postmenopausal Women
J Muñoz, BA Gower |
The Journal of clinical endocrinology and metabolism | 2003 |
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International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
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Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities
KD Niswender, MW Schwartz |
Frontiers in Neuroendocrinology | 2003 |
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Using Insulin as a Drug Rather Than as a Replacement Hormone During Acute Illness
A Pantaleo, J Zonszein |
Heart Disease | 2003 |
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Fatty acid mobilization from adipose tissue during exercise
JF Horowitz |
Trends in Endocrinology & Metabolism | 2003 |
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Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects—experiences from relatives and twin studies
H Beck-Nielsen, A Vaag, P Poulsen, M Gaster |
Best Practice & Research Clinical Endocrinology & Metabolism | 2003 |
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Insulin resistance as putative cause of chronic renal transplant dysfunction
AP de Vries, SJ Bakker, WJ van Son, JJ van der Heide, TH The, PE de Jong, RO Gans |
American Journal of Kidney Diseases | 2003 |
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The Effect of Leptin, Tumor Necrosis Factor-α (TNF-α), and Nitric Oxide (NO) Production on Insulin Resistance in Otsuka Long-Evans Fatty Rats
H IWAI, Y OHNO, N AOKI |
Endocrine Journal | 2003 |
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Neuroendocrinology of insulin resistance: metabolic and endocrine aspects of adiposity
G Dijk, K Vries, L Benthem, C Nyakas, B Buwalda, AJ Scheurink |
European Journal of Pharmacology | 2003 |
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Diabetes Mellitus and Heart Failure
D Jagasia, PH McNulty |
Congestive Heart Failure | 2003 |
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Prediabetes mellitus and its links to atherosclerosis
D Kramer, A Raji, J Plutzky |
Current Diabetes Reports | 2003 |
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Insulin resistance and impaired glucose tolerance in obese children and adolescents
B Tresaco, G Bueno, LA Moreno, JM Garagorri, M Bueno |
Journal of Physiology and Biochemistry | 2003 |
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The insulin resistance syndrome and coronary artery disease
DM Kendall, BE Sobel, AM Coulston, AL Harmel, BK McLean, V Peragallo-Dittko, JB Buse, VA Fonseca, JO Hill, RW Nesto, XF Sunyer |
Coronary Artery Disease | 2003 |
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Prevention of Obesity in Young Children: A Critical Challenge for Medical Professionals
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Effect of maternal feed restriction during pregnancy on glucose tolerance in the adult guinea pig
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Elevated plasma nonesterified fatty acids are associated with deterioration of acute insulin response in IGT but not NGT
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Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance
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Acute and chronic leptin treatment mediate contrasting effects on signaling, glucose uptake, and GLUT4 translocation in L6-GLUT4myc myotubes
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Trimetazidine Diminishes Fasting Glucose in Rats With Fasting Hyperglycemia: A Preliminary Study:
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Calorie restriction and aging: review of the literature and implications for studies in humans
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The American journal of clinical nutrition | 2003 |
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Insulin Resistance Syndrome in Children: Pathophysiology and Potential Management Strategies
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A New Cell Secreting Insulin
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Rôle des acides gras libres dans la sécrétion et l’action de l’insuline : mécanismes de la lipotoxicité
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Defective Activation of Atypical Protein Kinase C ζ and λ by Insulin and Phosphatidylinositol-3,4,5-(PO4)3 in Skeletal Muscle of Rats Following High-Fat Feeding and Streptozotocin-Induced Diabetes
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Endocrinology | 2003 |
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Lipodystrophy Syndrome in HIV
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Roles of Leptin and Ghrelin in the Loss of Body Weight Caused by a Low Fat, High Carbohydrate Diet
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The Journal of clinical endocrinology and metabolism | 2003 |
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Intramyocellular Lipid Changes in Men and Women during Aerobic Exercise: A 1H-Magnetic Resonance Spectroscopy Study
LJ White, MA Ferguson, SC McCoy, HW Kim |
The Journal of clinical endocrinology and metabolism | 2003 |
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Distribution of Fasting Plasma Insulin, Free Fatty Acids, and Glucose Concentrations and of Homeostasis Model Assessment of Insulin Resistance in a Representative Sample of Quebec Children and Adolescents
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Abdominal Adipose Tissue Distribution and Metabolic Risk:
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Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney
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Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1
Hubert C. Chen, Steven J. Smith, Zuleika Ladha, Dalan R. Jensen, Luis D. Ferreira, Leslie K. Pulawa, James G. McGuire, Robert H. Eckel, Robert E. Pitas, Robert V. Farese, Jr. |
Journal of Clinical Investigation | 2002 |
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Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
Kitt Falk Petersen, Elif Arioglu Oral, Sylvie Dufour, Douglas Befroy, Charlotte Ariyan, Chunli Yu, Gary W. Cline, Alex M. DePaoli, Simeon I. Taylor, Phillip Gorden, Gerald I. Shulman |
Journal of Clinical Investigation | 2002 |
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Mechanism by which High-Dose Aspirin Improves Glucose Metabolism in Type 2 Diabetes
Ripudaman S. Hundal, Kitt F. Petersen, Adam B. Mayerson, Pritpal S. Randhawa, Silvio Inzucchi, Steven B. Shoelson , Gerald I. Shulman |
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Defective fatty acid uptake modulates insulin responsiveness and the metabolic response to diet in the CD36 null mouse
Tahar Hajri, Xiao Xia Han, Arend Bonen, Nada A. Abumrad |
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Impaired glucose phosphorylation and transport in skeletal muscle causes insulin resistance in HIV-1 infected patients with lipodystrophy
Georg M.N. Behrens, Anne-Rose Boerner, Klaus Weber, Joerg van den Hoff, Johann Ockenga, Georg Brabant, Reinhold E. Schmidt |
Journal of Clinical Investigation | 2002 |
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Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats
J Kuhlmann, C Neumann-Haefelin, U Belz, J Kalisch, HP Juretschke, M Stein, E Kleinschmidt, W Kramer, AW Herling |
Diabetes | 2002 |
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Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells
DM Muoio, JM Way, CJ Tanner, DA Winegar, SA Kliewer, JA Houmard, WE Kraus, GL Dohm |
Diabetes | 2002 |
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Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36
JJ Luiken, DP Koonen, J Willems, A Zorzano, C Becker, Y Fischer, NN Tandon, GJ van der Vusse, A Bonen, JF Glatz |
Diabetes | 2002 |
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Emerging paradigms for understanding fatness and diabetes risk
SR Smith, E Ravussin |
Current Diabetes Reports | 2002 |
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IRS proteins and the common path to diabetes
MF White |
American journal of physiology. Endocrinology and metabolism | 2002 |
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Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes
JL Evans, ID Goldfine, BA Maddux, GM Grodsky |
Endocrine reviews | 2002 |
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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
T Yamauchi, J Kamon, Y Minokoshi, Y Ito, H Waki, S Uchida, S Yamashita, M Noda, S Kita, K Ueki, K Eto, Y Akanuma, P Froguel, F Foufelle, P Ferre, D Carling, S Kimura, R Nagai, BB Kahn, T Kadowaki |
Nature Medicine | 2002 |
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Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction
G Boden, GI Shulman |
European Journal of Clinical Investigation | 2002 |
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Somatropin and Glucose Homeostasis
JO J??rgensen, H Norrelund, F Conceicao, N Moller, JS Christiansen |
Treatments in Endocrinology | 2002 |
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Increased Fat Intake, Impaired Fat Oxidation, and Failure of Fat Cell Proliferation Result in Ectopic Fat Storage, Insulin Resistance, and Type 2 Diabetes Mellitus
E Ravussin, SR Smith |
Annals of the New York Academy of Sciences | 2002 |
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Troglitazone Ameliorates Abnormal Activity of Protein Tyrosine Phosphatase in Adipose Tissues of Otsuka Long-Evans Tokushima Fatty Rats
S Tagami, T Honda, H Yoshimura, H Homma, K Ohno, H Ide, S Sakaue, Y Kawakami |
The Tohoku Journal of Experimental Medicine | 2002 |
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Non-alcoholic steatohepatitis: Definitions and pathogenesis
C Day, S Saksena |
Journal of Gastroenterology and Hepatology | 2002 |
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Electrical Stimulation Improves Insulin Responses in a Human Skeletal Muscle Cell Model of Hyperglycemia
V Aas, S Torblå, MH Andersen, J Jensen, AC Rustan |
Annals of the New York Academy of Sciences | 2002 |
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Insulin Stimulation of Hepatic Triacylglycerol Secretion in the Insulin-Replete State
VA Zammit |
Annals of the New York Academy of Sciences | 2002 |
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Molecular insights into insulin action and secretion
CJ Rhodes, MF White |
European Journal of Clinical Investigation | 2002 |
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Cytoplasmic fatty acid-binding proteins: emerging roles in metabolism and atherosclerosis
JB Boord, S Fazio, MR Linton |
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Fatty acids, triglycerides, and glucose metabolism: recent insights from knockout mice
HC Chen, RV Farese |
Current Opinion in Clinical Nutrition and Metabolic Care | 2002 |
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AJ Sanyal |
Journal of Gastroenterology and Hepatology | 2002 |
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DM Muoio, GL Dohm |
Best Practice & Research Clinical Endocrinology & Metabolism | 2002 |
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Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content
S Neschen, I Moore, W Regittnig, CL Yu, Y Wang, M Pypaert, KF Petersen, GI Shulman |
American journal of physiology. Endocrinology and metabolism | 2002 |
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Cellular mechanism of insulin resistance in skeletal muscle
KF Petersen, GI Shulman |
Journal of the Royal Society of Medicine | 2002 |
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A central role for JNK in obesity and insulin resistance
J Hirosumi, G Tuncman, L Chang, CZ Görgün, KT Uysal, K Maeda, M Karin, GS Hotamisligil |
Nature | 2002 |
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Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance
F Mauvais-Jarvis, RN Kulkarni, CR Kahn |
Clinical Endocrinology | 2002 |
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Exercise to Reduce Cardiovascular Risk — How Much Is Enough?
AR Tall |
New England Journal of Medicine | 2002 |
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Evaluation of Liver Fatty Acid Oxidation in the Leptin-Deficient Obese Mouse
AE Brix, A Elgavish, TR Nagy, BA Gower, WJ Rhead, PA Wood |
Molecular Genetics and Metabolism | 2002 |
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Anesthesia for patients with diabetes mellitus
SF Dierdorf |
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GLUT4 expression at the plasma membrane is related to fibre volume in human skeletal muscle fibres
M Gaster, W Vach, H Beck-Nielsen, HD Schroder |
APMIS | 2002 |
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Bezafibrate-induced improvement in glucose uptake and endothelial function in protease inhibitor-associated insulin resistance
T Nystrom, G Bratt, A Sjoholm |
Journal of Internal Medicine | 2002 |
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Pathogenesis of steatohepatitis
CP Day |
Best Practice & Research Clinical Gastroenterology | 2002 |
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M USCLE T RIGLYCERIDE AND I NSULIN R ESISTANCE
DE Kelley, BH Goodpaster, L Storlien |
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Blue Books of Practical Neurology
PE Hart, DC de Vivo, AH Schapira |
Blue Books of Practical Neurology | 2002 |
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Rationale for and role of thiazolidinediones in type 2 diabetes mellitus
HE Lebovitz |
The American Journal of Cardiology | 2002 |
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Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus
KF Petersen, GI Shulman |
The American Journal of Cardiology | 2002 |
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Annual Reports on NMR Spectroscopy
CL Lean, RL Somorjai, IC Smith, P Russell, CE Mountford |
Annual Reports on NMR Spectroscopy | 2002 |
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Insulin Resistance and Insulin Resistance Syndrome
A Cincotta |
Insulin Resistance and Insulin Resistance Syndrome | 2002 |
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Disordered Fat Storage and Mobilization in the Pathogenesis of Insulin Resistance and Type 2 Diabetes
GF Lewis, A Carpentier, K Adeli, A Giacca |
Endocrine reviews | 2002 |
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Adaptation and Maladaptation of the Heart in Diabetes: Part I: General Concepts
H Taegtmeyer, P McNulty, ME Young |
Circulation | 2002 |
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Medical Management of Diabetes and Heart Disease
M LeWinter |
Medical Management of Diabetes and Heart Disease | 2002 |
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Obligatory role of membrane events in the regulatory effect of metformin on the respiratory chain function
D Detaille, B Guigas, X Leverve, N Wiernsperger, P Devos |
Biochemical Pharmacology | 2002 |
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Estrogen Can Prevent or Reverse Obesity and Diabetes in Mice Expressing Human Islet Amyloid Polypeptide
JG Geisler, W Zawalich, K Zawalich, JR Lakey, H Stukenbrok, AJ Milici, WC Soeller |
Diabetes | 2002 |
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Troglitazone but not Metformin Restores Insulin-Stimulated Phosphoinositide 3-Kinase Activity and Increases p110 Protein Levels in Skeletal Muscle of Type 2 Diabetic Subjects
YB Kim, TP Ciaraldi, A Kong, D Kim, N Chu, P Mohideen, S Mudaliar, RR Henry, BB Kahn |
Diabetes | 2002 |
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Gene Expression Profile in Skeletal Muscle of Type 2 Diabetes and the Effect of Insulin Treatment
R Sreekumar, P Halvatsiotis, JC Schimke, KS Nair |
Diabetes | 2002 |
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Regulation of Glucose Transport and Insulin Signaling by Troglitazone or Metformin in Adipose Tissue of Type 2 Diabetic Subjects
TP Ciaraldi, AP Kong, NV Chu, DD Kim, S Baxi, M Loviscach, R Plodkowski, R Reitz, M Caulfield, S Mudaliar, RR Henry |
Diabetes | 2002 |
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Rosiglitazone but Not Metformin Enhances Insulin- and Exercise-Stimulated Skeletal Muscle Glucose Uptake in Patients With Newly Diagnosed Type 2 Diabetes
K Hallsten, KA Virtanen, F Lonnqvist, H Sipila, A Oksanen, T Viljanen, T Ronnemaa, J Viikari, J Knuuti, P Nuutila |
Diabetes | 2002 |
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The Diabetic Phenotype Is Conserved in Myotubes Established From Diabetic Subjects: Evidence for Primary Defects in Glucose Transport and Glycogen Synthase Activity
M Gaster, I Petersen, K Hojlund, P Poulsen, H Beck-Nielsen |
Diabetes | 2002 |
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Transplantation of Adipose Tissue Lacking Leptin Is Unable to Reverse the Metabolic Abnormalities Associated With Lipoatrophy
C Colombo, JJ Cutson, T Yamauchi, C Vinson, T Kadowaki, O Gavrilova, ML Reitman |
Diabetes | 2002 |
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Sustained Exposure of L6 Myotubes to High Glucose and Insulin Decreases Insulin-Stimulated GLUT4 Translocation but Upregulates GLUT4 Activity
C Huang, R Somwar, N Patel, W Niu, D Torok, A Klip |
Diabetes | 2002 |
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Insulin Resistance, Defective Insulin Receptor Substrate 2--Associated Phosphatidylinositol-3' Kinase Activation, and Impaired Atypical Protein Kinase C ( / ) Activation in Myotubes From Obese Patients With Impaired Glucose Tolerance
P Vollenweider, B Menard, P Nicod |
Diabetes | 2002 |
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Banting Lecture 2001: Dysregulation of Fatty Acid Metabolism in the Etiology of Type 2 Diabetes
JD McGarry |
Diabetes | 2002 |
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Effect of Weight Loss on Insulin Sensitivity and Intramuscular Long-Chain Fatty Acyl-CoAs in Morbidly Obese Subjects
JA Houmard, CJ Tanner, C Yu, PG Cunningham, WJ Pories, KG MacDonald, GI Shulman |
Diabetes | 2002 |
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Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice
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Nature Genetics | 2002 |
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Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B
A Cheng, N Uetani, PD Simoncic, VP Chaubey, A Lee-Loy, CJ McGlade, BP Kennedy, ML Tremblay |
Developmental Cell | 2002 |
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Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity
Ranjana Sinha, Sylvie Dufour, Kitt Falk Petersen, Vincent LeBon, Staffan Enoksson, Yong-Zhan Ma, Mary Savoye, Douglas L Rothman, Gerald I Shulman, Sonia Caprio |
Diabetes | 2002 |
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Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
Wei-Shiung Yang, Chi-Yuan Jeng, Ta-Jen Wu, Sachiyo Tanaka, Tohru Funahashi, Yuji Matsuzawa, Jao-Ping Wang, Chi-Ling Chen, Tong-Yuan Tai, Lee-Ming Chuang |
Diabetes care | 2002 |
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The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
Adam B. Mayerson, Ripudaman S. Hundal, Sylvie Dufour, Vincent Lebon, Douglas Befroy, Gary W. Cline, Staffan Enocksson, Silvio E. Inzucchi, Gerald I. Shulman, Kitt F. Petersen |
Diabetes | 2002 |
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WY14,643, a Peroxisome Proliferator-activated Receptor α (PPARα) Agonist, Improves Hepatic and Muscle Steatosis and Reverses Insulin Resistance in Lipoatrophic A-ZIP/F-1 Mice
CJ Chou, M Haluzik, C Gregory, KR Dietz, C Vinson, O Gavrilova, ML Reitman |
The Journal of biological chemistry | 2002 |
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Serine Phosphorylation of Insulin Receptor Substrate 1 by Inhibitor κB Kinase Complex
Z Gao, D Hwang, F Bataille, M Lefevre, D York, MJ Quon, J Ye |
The Journal of biological chemistry | 2002 |
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Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic β-Cells (INS-1)
CE Wrede, LM Dickson, MK Lingohr, I Briaud, CJ Rhodes |
The Journal of biological chemistry | 2002 |
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c-Jun N-terminal Kinase (JNK) Mediates Feedback Inhibition of the Insulin Signaling Cascade
YH Lee, J Giraud, RJ Davis, MF White |
The Journal of biological chemistry | 2002 |
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Changes in FAT/CD36, UCP2, UCP3 and GLUT4 gene expression during lipid infusion in rat skeletal and heart muscle
R Vettor, R Fabris, R Serra, AM Lombardi, C Tonello, M Granzotto, MO Marzolo, MO Carruba, D Ricquier, G Federspil, E Nisoli |
International Journal of Obesity | 2002 |
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Adiponectin enhances insulin action by decreasing ectopic fat deposition
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The Pharmacogenomics Journal | 2002 |
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Normal insulin sensitivity and IMCL content in overweight humans are associated with higher fasting lipid oxidation
G Perseghin, P Scifo, M Danna, A Battezzati, S Benedini, E Meneghini, AD Maschio, L Luzi |
American journal of physiology. Endocrinology and metabolism | 2002 |
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Fatty acid transport: the roads taken
JE Schaffer |
American journal of physiology. Endocrinology and metabolism | 2002 |
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Abdominal adiposity and insulin resistance in obese men
R Ross, J Aru, J Freeman, R Hudson, I Janssen |
American journal of physiology. Endocrinology and metabolism | 2002 |
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D Pessayre, A Mansouri, B Fromenty |
AJP Gastrointestinal and Liver Physiology | 2002 |
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Inhibition of glycogen synthesis by fatty acid in C 2 C 12 muscle cells is independent of PKC-α, -ε, and -θ
R Cazzolli, DL Craig, TJ Biden, C Schmitz-Peiffer |
American journal of physiology. Endocrinology and metabolism | 2002 |
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Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content
S Neschen, I Moore, W Regittnig, CL Yu, Y Wang, M Pypaert, KF Petersen, GI Shulman |
American journal of physiology. Endocrinology and metabolism | 2002 |
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Molecular Links Between Obesity and Cardiovascular Disease:
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American Journal of Therapeutics | 2002 |
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Energy Restriction Reduces Long-Chain Saturated Fatty Acids Associated with Plasma Lipids in Aging Male Rats
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The Journal of nutrition | 2002 |
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Dietary and lifestyle interventions in the management of the metabolic syndrome: present status and future perspective
K Minehira, L Tappy |
European Journal of Clinical Nutrition | 2002 |
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Do Long-Chain Acyl-CoA Synthetases Regulate Fatty Acid Entry into Synthetic Versus Degradative Pathways?
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The Journal of nutrition | 2002 |
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Nature | 2002 |
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Brain Somatic Cross-Talk and the Central Control of Metabolism
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PPARα suppresses insulin secretion and induces UCP2 in insulinoma cells
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Journal of lipid research | 2002 |
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Vanadium increases GLUT4 in diabetic rat skeletal muscle.
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Molecular and Cellular Biochemistry | 2002 |
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Insulin/IGF-1 and TNFalpha stimulate phosphorylation of IRS-1 at inhibitory SER307 via distinct pathways
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Journal of Clinical Investigation | 2001 |
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Effect of triiodothyronine on mitochondrial energy coupling activity in human skeletal muscle
Vincent Lebon, Sylvie Dufour, Kitt Falk Petersen, Jianming Ren, Beat M. Jucker, Lori A. Slezak, Gary W. Cline, Douglas L. Rothman, Gerald I. Shulman |
Journal of Clinical Investigation | 2001 |
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Both RXR antagonist and PPAR-gamma antagonist provide a novel therapeutic strategy for obesity and type 2 diabetes
Toshimasa Yamauchi, Hironori Waki, Junji Kamon, Koji Murakami, Kiyoto Motojima, Kajuro Komeda, Hiroshi Miki, Naoto Kubota, Yasuo Terauchi, Atsuko Tsuchida, Nobuyo Tsuboyama-Kasaoka, Naoko Yamauchi, Tomohiro Ide, Wataru Hori, Shigeaki Kato, Masashi Fukayama, Yasuo Akanuma, Osamu Ezaki, Akiko Itai, Ryozo Nagai, Satoshi Kimura, Kazuyuki Tobe, Hiroyuki Kagechika, Koichi Shudo and Takashi Kadowaki |
Journal of Clinical Investigation | 2001 |
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The effect of salicylates on insulin sensitivity
Mihai Netea |
Journal of Clinical Investigation | 2001 |
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Turning down insulin signaling
Morris Birnbaum |
Journal of Clinical Investigation | 2001 |
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Calpains play a role in insulin secretion and action
SK Sreenan, YP Zhou, K Otani, PA Hansen, KP Currie, CY Pan, JP Lee, DM Ostrega, W Pugh, Y Horikawa, NJ Cox, CL Hanis, CF Burant, AP Fox, GI Bell, KS Polonsky |
Diabetes | 2001 |
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High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells
G Sweeney, J Keen, R Somwar, D Konrad, R Garg, A Klip |
Endocrinology | 2001 |
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Insulin signalling and the regulation of glucose and lipid metabolism
AR Saltiel, CR Kahn |
Nature | 2001 |
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New drug targets for type 2 diabetes and the metabolic syndrome
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Nature | 2001 |
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Non-invasive studies of glycogen metabolism in human skeletal muscle using nuclear magnetic resonance spectroscopy
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Current Opinion in Clinical Nutrition and Metabolic Care | 2001 |
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Prostaglandylinositol cyclic phosphate (cPIP): a novel second messenger of insulin action. Comparative analysis of two kinds of ?insulin mediators?
PN Shashkin, HK Wasner, HK Ortmeyer, BC Hansen |
Diabetes/Metabolism Research and Reviews | 2001 |
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Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes
CY Zhang, G Baffy, P Perret, S Krauss, O Peroni, D Grujic, T Hagen, AJ Vidal-Puig, O Boss, YB Kim, XX Zheng, MB Wheeler, GI Shulman, CB Chan, BB Lowell |
Cell | 2001 |
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New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes
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Cell | 2001 |
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Identification of Ser1275 and Ser1309 as Autophosphorylation Sites of the Human Insulin Receptor in Intact Cells
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Biochemical and Biophysical Research Communications | 2001 |
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Insulin resistance: a phosphorylation-based uncoupling of insulin signaling
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Trends in Cell Biology | 2001 |
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CD36, insulin resistance, and coronary heart disease
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The Lancet | 2001 |
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RG Vernon, RG Denis, A Sørensen |
Domestic Animal Endocrinology | 2001 |
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Cardiovascular implications of insulin resistance and non–insulin-dependent diabetes mellitus
PH McNulty, SM Ettinger, IC Gilchrist, M Kozak, CE Chambers |
Journal of Cardiothoracic and Vascular Anesthesia | 2001 |
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Pharmacological Antilipolysis Restores Insulin Sensitivity During Growth Hormone Exposure
S Nielsen, N Moller, JS Christiansen, JO Jorgensen |
Diabetes | 2001 |
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A Novel Variant of Glutamine: Fructose-6-Phosphate Amidotransferase-1 (GFAT1) mRNA Is Selectively Expressed in Striated Muscle
JE DeHaven, KA Robinson, BA Nelson, MG Buse |
Diabetes | 2001 |
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In Muscle-Specific Lipoprotein Lipase-Overexpressing Mice, Muscle Triglyceride Content Is Increased Without Inhibition of Insulin-Stimulated Whole-Body and Muscle-Specific Glucose Uptake
PJ Voshol, MC Jong, VE Dahlmans, D Kratky, S Levak-Frank, R Zechner, JA Romijn, LM Havekes |
Diabetes | 2001 |
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PPAR- -Null Mice Are Protected From High-Fat Diet-Induced Insulin Resistance
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Diabetes | 2001 |
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Impaired Regulation of Glucose Transporter 4 Gene Expression in Insulin Resistance Associated with in Utero Undernutrition 1
D Jaquet, H Vidal, R Hankard, P Czernichow, C Levy-Marchal |
The Journal of clinical endocrinology and metabolism | 2001 |
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NEW INSIGHTS INTO INSULIN RESISTANCE PATHOPHYSIOLOGY: HOW IT AFFECTS GLUCOSE AND LIPID METABOLISM
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ACTA CLINICA BELGICA | 2001 |
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Lipotoxicity and glucotoxicity in type 2 diabetes: Effects on development and progression
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Postgraduate Medicine | 2001 |
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Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes
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Journal of Clinical Investigation | 2001 |
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Phosphorylation of Ser 307 in Insulin Receptor Substrate-1 Blocks Interactions with the Insulin Receptor and Inhibits Insulin Action
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The Journal of biological chemistry | 2001 |
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A Phosphatidylinositol 3-Kinase-independent Insulin Signaling Pathway to N-WASP/Arp2/3/F-actin Required for GLUT4 Glucose Transporter Recycling
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The Journal of biological chemistry | 2001 |
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Regulation of Insulin/Insulin-like Growth Factor-1 Signaling by Proteasome-mediated Degradation of Insulin Receptor Substrate-2
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The Journal of biological chemistry | 2001 |
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Defective Fatty Acid Uptake in the Spontaneously Hypertensive Rat Is a Primary Determinant of Altered Glucose Metabolism, Hyperinsulinemia, and Myocardial Hypertrophy
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The Journal of biological chemistry | 2001 |
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Membrane Topology of the Murine Fatty Acid Transport Protein 1
SE Lewis, LL Listenberger, DS Ory, JE Schaffer |
The Journal of biological chemistry | 2001 |
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Diabetes: Dialogue between muscle and fat
MJ Birnbaum |
Nature | 2001 |
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Intracellular signalling: Key enzyme in leptin-induced anorexia
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Nature | 2001 |
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Glucose uptake and glucose transporter proteins in skeletal muscle from undernourished rats
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American journal of physiology. Endocrinology and metabolism | 2001 |
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Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/RGL
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Molecular and cellular biology | 2001 |
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You are what you secrete
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Nature Medicine | 2001 |
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Diseases of liporegulation: new perspective on obesity and related disorders
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The FASEB Journal | 2001 |
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Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats
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Nature Genetics | 2001 |
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Journal of Clinical Investigation | 2000 |
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Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
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Journal of Clinical Investigation | 2000 |
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