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Prodrug-activating systems in suicide gene therapy

Caroline J. Springer, Ion Niculescu-Duvaz

Caroline J. Springer, Ion Niculescu-Duvaz

Published May 1, 2000
Citation Information: J Clin Invest. 2000;105(9):1161-1167. https://doi.org/10.1172/JCI10001.

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Citations to this article (170)

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Gene-Directed Enzyme/Prodrug Therapy of Rat Brain Tumor Mediated by Human Mesenchymal Stem Cell Suicide Gene Extracellular Vesicles In Vitro and In Vivo. Tibensky M, Jakubechova J, Altanerova U, Pastorakova A, Rychly B, Baciak L, Mravec B, Altaner C	Cancers	2022
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Microbial cytosine deaminase is a programmable anticancer prodrug mediating enzyme: antibody, and gene directed enzyme prodrug therapy. El-Sayed ASA, Mohamed NZ, Yassin MA, Amer MM, El-Sharkawy R, El-Sayed N, Ali MG	Heliyon	2022
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Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes A Hajri, S Wack, P Lehn, JP Vigneron, JM Lehn, J Marescaux, M Aprahamian	Cancer Gene Therapy	2003
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Oncolytic herpes simplex virus vectors for cancer virotherapy S Varghese, SD Rabkin	Cancer Gene Therapy	2002
Manufacturing of Gene Therapeutics G Subramanian		2002
GENE THERAPY FOR PROSTATE CANCER: CURRENT STATUS AND FUTURE PROSPECTS K Harrington, C Spitzweg, A Bateman, J Morris, R Vile	The Journal of Urology	2001
Nucleoside Analog Cytotoxicity and Bystander Cell Killing of Cancer Cells Expressing Drosophila melanogaster Deoxyribonucleoside Kinase in the Nucleus or Cytosol X Zheng, M Johansson, A Karlsson	Biochemical and Biophysical Research Communications	2001
GENE THERAPY FOR PROSTATE CANCER: KJ Harrington, C Spitzweg, AR Bateman, JC Morris, RG Vile	The Journal of Urology	2001
Adenovirus-Mediated Thymidine Kinase Gene Therapy in Combination with Topotecan for Patients with Recurrent Ovarian Cancer: 2.5-Year Follow-Up A Hasenburg, XW Tong, DC Ph.D., A Rojas-Martinez, C Nyberg-Hoffman, AL Kaplan, RH Kaufman, I Ramzy, E Aguilar-Cordova, DG Kieback	Gynecologic Oncology	2001
A minimum c-erbB-2 promoter-mediated expression of herpes simplex virus thymidine kinase gene confers selective cytotoxicity of human breast cancer cells to ganciclovir T Maeda, J O-Wang, H Matsubara, T Asano, T Ochiai, S Sakiyama, M Tagawa	Cancer Gene Therapy	2001
Growth Inhibition of Cancer Cells by Co-Transfection of Diphtheria Toxin A-Chain Gene Plasmid with Bovine Leukemia Virus-Tax Expression Vector Tana, S Watarai, Y Aida, S Tajima, H Kakidani, M Onuma, H Kodama	Microbiology and Immunology	2001
Use of suicide gene-expressing donor T-cells to control alloreactivity after haematopoietic stem cell transplantation P Tiberghien	Journal of Internal Medicine	2001
An introduction to gene therapy and its potential prenatal use: Gene therapy and its potential prenatal use AC Staff	Acta Obstetricia et Gynecologica Scandinavica	2001
Immunomodulation of cancer: potential use of selectively replicating agents S Agha-Mohammadi, MT Lotze	Journal of Clinical Investigation	2000
Regulatable systems: applications in gene therapy and replicating viruses S Agha-Mohammadi, MT Lotze	Journal of Clinical Investigation	2000
Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer T Hermiston	Journal of Clinical Investigation	2000
Cancer gene therapy: developments to 2000 AR Bateman, KJ Harrington, AA Melcher, RG Vile	Expert Opinion on Investigational Drugs	2000
Pancreatic Disease EC Kafka, MH Kalser	Postgraduate Medicine	1975

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