No articles were found with this tag.

Complement C3 inhibitor AMY-101 in adults with periodontal inflammation – clinical trial
In this episode, the authors explain that local delivery of the complement C3 inhibitor AMY-101 in patients with gingivitis was safe, well tolerated, and led to significant and sustained reduction of clinical indices of gingival inflammation...
Published December 1, 2021
Video Abstracts
Hallmarks of the immunometabolic imbalance in COVID-19
In this episode, Marina Kreutz and colleagues discuss how their findings provide evidence of an immunometabolic dysregulation in COVID-19, which can be mitigated by dexamethasone treatment...
Published November 19, 2021
Video Abstracts
CHI3L1 regulates PD-L1 and anti–CHI3L1–PD-1 antibody elicits synergistic antitumor responses
In this episode, Jack Elias explains that these studies demonstrate that CHI3L1 contributes to pulmonary metastasis by regulating PD-1-PD-L-1 axis, and simultaneous targeting of CHI3L1 and PD-1/PD-L1 axis elicits synergistic antitumor responses...
Published November 1, 2021
Video Abstracts
Desmin degradation and dilatation in hiPSC-derived engineered heart tissues
In this episode, Peter van der Meer and Mathilde Vermeer explain the pathological role of KLHL24 methionine start-codon mutations in the development of dilated cardiomyopathy using hiPSC-derived dynamically loaded engineered heart tissues...
Published September 3, 2021
Video Abstracts
Human pulmonary tuberculosis and doxycycline therapy
In this episode, Catherine Ong explains that adjunctive doxycycline with standard anti-TB treatment suppresses pathological MMPs in pulmonary tuberculosis patients...
Published August 5, 2021
Video Abstracts
Extracellular matrix protein laminin β1 and behaviors in mice
In this episode, Ceng Luo and Zhen-Zhen Li explain that extracellular matrix laminin β1 protects against neuropathic pain and related anxiodepression through integrin β1-dependent actin reorganization...
Published August 2, 2021
Video Abstracts
Zonulin-dependent loss of gut mucosal barrier and MIS-C
In this episode, the authors explain that in multisystem inflammatory syndrome in children (MIS-C), increased gastrointestinal mucosal permeability allows SARS-CoV-2 antigens in the GI tract to leak into the bloodstream...
Published July 15, 2021
Video Abstracts
Hemophilia A and immune response
In this episode, Valder Arruda explains that depletion of the cytokine B cell activating factor in hemophilia A may provide a way to prevent or eradicate factor VIII inhibitors...
Published July 9, 2021
Video Abstracts
Efficient maternal to neonatal transfer of antibodies
In this episode, Michal Kovo explains that antenatal BNT162b2 mRNA vaccination induces a robust maternal humoral response that effectively transfers to the fetus, supporting the role of vaccination during pregnancy...
Published July 1, 2021
Video Abstracts
Immune checkpoint receptors for HBV infection
In this episode, Shie-Liang Hsieh and Tsung-Yu Tsai explain that HBV interacts with SIGLEC-3 and causes impairment of host immunity...
Published June 1, 2021
Video Abstracts
Advertisement