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BMX controls in cancer
In this episode, Nima Sharifi and Xiuxiu Li discuss how the BMX kinase regulates androgen and estrogen biosynthesis and is a drug target for sex steroid dependent cancers...
Published January 17, 2023
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CD69 expression protects from immune damage after MI
In this episode, Dr. Blanco-Domínguez discusses CD69 expression on regulatory T cells after myocardial infarction controls immune homeostasis...
Published November 1, 2022
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Durability of AZD1222 COVID-19 vaccine over 6 months
In this episode, Magdalena Sobieszczyk explains the paper and that it provides comprehensive safety information and data on durability of protection and immunogenicity of AZD1222...
Published September 15, 2022
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Immune responses and the rejection of colonized solid organ transplants
In this episode, Isabella Pirozzolo explains that following transplantation, microbiota-colonized organs have a shorter half-life than sterile organs. In the paper, the authors show that host-versus-commensal immunity participates in graft damage...
Published September 1, 2022
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Targeting hepatic kisspeptin receptors and nonalcoholic fatty liver disease
In this episode, Stephania Guzman explains that this study establishes the kisspeptin receptor as a therapeutic target to treat nonalcoholic fatty liver disease...
Published May 18, 2022
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Food addiction vulnerability in mice and humans and miRNA signatures
In this episode, Rafael Maldonado and Elena Martín-García explain how similar patterns of miRNAs signatures of food addiction vulnerability are present in animals and humans...
Published May 16, 2022
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Efferocytosis induces VEGFC to improve cardiac injury and inflammation
In this episode, Guillermo Oliver and Ed Thorp discuss how cardiac VEGF-C is sourced from macrophages after efferocytosis to ameliorate cardiac injury and inflammation...
Published May 2, 2022
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Gut-derived bacterial toxins and HIV-1 infection
In this episode, Souheil-Antoine Younes explains that their findings propose that toxic solutes from the gut bacterial flora may impair CD4+ T cell recovery during ART and may contribute to CD4+ T cell lymphopenia characteristic of INRs...
Published May 2, 2022
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Tertiary lymphoid tissue expansion and kidney injury are promoted by CD153/CD30 signaling
In this episode, Motoko Yanagita and Yuki Sato explain that CD153-CD30 signaling is required for tertiary lymphoid tissue expansion and represents a therapeutic target for kidney diseases in the elderly...
Published January 31, 2022
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COVID-19 outcomes in African American patients using ACE inhibitors/angiotensin receptor blockers
In this episode, Li Li explains that in-hospital use of angiotensin receptor blockers was associated with a significant reduction in mortality among COVID-19-positive African American patients...
Published December 3, 2021
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