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Chilling out and firming up
In this episode of Author's Take, Takeshi Yoneshiro and Masayuki Saito discuss their recent study in which subjects exposed subjects to a daily cold stimulus for 6 weeks had increased BAT activation and reduced overall fat mass.
Published July 15, 2013
Video Abstracts
MicroRNA modulates expression of atrial natiuretic peptide
Atrial natriuretic peptide is negatively regulated by microRNA-425
Published July 15, 2013
Video Abstracts
β-globin gene transfer in human bone marrow for sickle cell disease
Gene transfer therapy for Sickle cell disease
Published July 1, 2013
Video Abstracts
Transcription factor ATF3 links host adaptive response to breast cancer metastasis
Tsonwin Hai and colleagues discuss how the transcription factor ATF3 acts as a key regulator of the host immune response to cancer.
Published June 10, 2013
Video Abstracts
Reducing TMPRSS6 ameliorates hemochromatosis and beta-thalassemia in mice
Brett Monia and Stefano Rivella discuss how reduction of TMPRSS6 expression with antisense oligonucleotides ameliorates iron metabolism disorders in mice.
Published March 25, 2013
Video Abstracts
The TGR5 receptor mediates bile acid-induced itch and analgesia
Carlos Corvera of UCSF and Nigel Bunnett of Monash University discuss their study demonstrating that bile acids cause itch and analgesia by activating the TGR5 receptor in neurons.
Published March 25, 2013
Video Abstracts
Increased brain uptake and oxidation of acetate in heavy drinkers
Increased brain uptake and oxidation of acetate in heavy drinkers Graeme Mason of Yale University discusses how heavy drinking influences metabolism and leads to alternate fuel use in the brain.
Published March 8, 2013
Video Abstracts
Brain-wide pathway for waste clearance captured by contrast enhanced MRI
Helene Benveniste of Stony Brook University discusses the use of contrast-enhanced MRI to visualize the glymphatic system, a paravascular pathway that facilitates the clearance of waste and solutes from the cerebrospinal fluid and interstitial fluid of the brain.
Published February 22, 2013
Video Abstracts
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis
Jane Salmon, Carl Blobel, Priya Darshinee Issuree, and Thorsten Maretzky of the Weill Cornell University Hospital for Special Surgery discuss the role of iRHOM2 in inflammatory arthritis.
Published January 25, 2013
Video Abstracts
CXCR5+ T helper cells mediate protective immunity against tuberculosis
Shabaana Khader of the University of Pittsburgh discusses the identification of immune parameters that distinguish active and latent TB infections.
Published January 2, 2013
Video Abstracts
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