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Stanford I. Lamberg, Albert Dorfman
Citation Information: J Clin Invest. 1973;52(10):2428-2433. https://doi.org/10.1172/JCI107433.
Stanford I. Lamberg, Albert Dorfman
Published October 1, 1973
Citation Information: J Clin Invest. 1973;52(10):2428-2433. https://doi.org/10.1172/JCI107433.
Abstract
Increased amounts of hyaluronic acid accumulate in fibroblasts cultured from patients with Marfan's disease, an autosomal dominant disorder. In the recessive Hurler's disease, the storage of glycosaminoglycan (GAG) is due to impaired degradation. This study examines the kinetics of GAG accumulation in Marfan's disease in order to determine whether the mechanism of accumulation differs from that in Hurler's disease.
Authors
Stanford I. Lamberg, Albert Dorfman
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