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Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis
Humberto Reyes, … , Zenaida Gatmaitan, Irwin M. Arias
Humberto Reyes, … , Zenaida Gatmaitan, Irwin M. Arias
Published November 1, 1971
Citation Information: J Clin Invest. 1971;50(11):2242-2252. https://doi.org/10.1172/JCI106721.
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Research Article

Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis

Abstract

The process by which various anions, including bilirubin and several dyes, drugs, hormones and their metabolites, are transferred from plasma into the liver cell is poorly understood. Two hepatic cytoplasmic proteins, Y and Z, that bind various organic anions in vivo and in vitro have been postulated to be involved in this process.

Authors

Humberto Reyes, A. Jonathan Levi, Zenaida Gatmaitan, Irwin M. Arias

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