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Citation Information: J Clin Invest. 1967;46(9):1402-1412. https://doi.org/10.1172/JCI105632.
Abstract
A method is described which measures the local effectiveness of the myocardial circulation, expressed as a clearance constant. Uniform clearance constants have been demonstrated in the normal canine and human myocardium. A distinct difference in clearance constants has been demonstrated between the normal canine myocardium and areas of naturally occurring disease. Heterogeneous clearance constants have been found in a majority of human subjects with coronary artery disease—the lowest rates being noted in areas of fibrous aneurysm.
Authors
Jay M. Sullivan, Warren J. Taylor, William C. Elliott, Richard Gorlin
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