Carla Heise, David H. Kirn
Title and authors | Publication | Year |
---|---|---|
Harnessing State-of-the-Art Gene Therapy to Transform Oral Cancer Treatment.
Zhang W, Zhang Y, Yang X, Chai H |
Biochemical genetics | 2025 |
Cancer immunotherapies: A hope for the uncurable?
Hamdan F, Cerullo V |
2023 | |
Oncolytic Adenoviruses for Cancer Therapy
L Tripodi, M Vitale, V Cerullo, L Pastore |
International journal of molecular sciences | 2021 |
Clinical Trials of Oncolytic Viruses in Breast Cancer.
Carter ME, Koch A, Lauer UM, Hartkopf AD |
Frontiers in Oncology | 2021 |
Insights into the Mechanisms of Action of MDA-7/IL-24: A Ubiquitous Cancer-Suppressing Protein.
Modi J, Roy A, Pradhan AK, Kumar A, Talukdar S, Bhoopathi P, Maji S, Mannangatti P, Sanchez De La Rosa D, Li J, Guo C, Subler MA, Windle JJ, Cavenee WK, Sarkar D, Wang XY, Das SK, Emdad L, Fisher PB |
International journal of molecular sciences | 2021 |
Oncolytic effect of Midkine promoter–based conditionally replicating adenoviruses expressing EGFR siRNA in head and neck squamous cancer cell line T891
N Uehara, N Otsuki, M Kubo, J Kitamoto, Y Kojima, M Teshima, H Shinomiya, T Shirakawa, K Nibu |
EMBO reports | 2020 |
Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells
E Ehrke-Schulz, S Heinemann, L Schulte, M Schiwon, A Ehrhardt |
Cancers | 2020 |
Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics
B Cambien, K Lebrigand, A Baeri, N Nottet, C Compin, A Lamit, O Ferraris, CN Peyrefitte, V Magnone, J Henriques, LE Zaragosi, S Giorgetti-Peraldi, F Bost, M Gautier-Isola, R Rezzonico, P Barbry, R Barthel, B Mari, G Vassaux, E Bartee |
PLoS pathogens | 2020 |
Oncolytic adenoviruses: a game changer approach in the battle between cancer and the immune system
V Cervera-Carrascon, R Havunen, A Hemminki |
Expert Opinion on Biological Therapy | 2019 |
Physically crosslinked injectable hydrogels for long-term delivery of oncolytic adenoviruses for cancer treatment
TM Le, BK Jung, Y Li, HT Duong, TL Nguyen, JW Hong, CO Yun, DS Lee |
Biomaterials Science | 2019 |
Cancer terminator viruses ( CTV ): A better solution for viral-based therapy of cancer
L Emdad, SK Das, XY Wang, D Sarkar, PB Fisher |
Journal of Cellular Physiology | 2018 |
Adenoviral Vectors Armed with Cell Fusion-Inducing Proteins as Anti-Cancer Agents
JD Papa, R Parks |
Viruses | 2017 |
Mesenchymal stromal cells for the delivery of oncolytic viruses in gliomas
BC Kerrigan, Y Shimizu, M Andreeff, FF Lang |
Cytotherapy | 2017 |
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent
P Wang, X Li, J Wang, D Gao, Y Li, H Li, Y Chu, Z Zhang, H Liu, G Jiang, Z Cheng, S Wang, J Dong, B Feng, LS Chard, NR Lemoine, Y Wang |
Nature Communications | 2017 |
Interleukin-12-expressing oncolytic virus: A promising strategy for cancer immunotherapy
AA Alkayyal, AB Mahmoud, RC Auer |
Journal of Taibah University Medical Sciences | 2016 |
Conditionally replicating oncolytic adenoviral vector expressing arresten and tumor necrosis factor-related apoptosis-inducing ligand experimentally suppresses lung carcinoma progression
S Li, Z Qi, H Li, J Hu, D Wang, X Wang, Z Feng |
Molecular medicine reports | 2015 |
Oncolytic viruses: From bench to bedside with a focus on safety
PR Buijs, JH Verhagen, CH van Eijck, BG van Hoogen |
Human Vaccines & Immunotherapeutics | 2015 |
Activation of Cyclic Adenosine Monophosphate Pathway Increases the Sensitivity of Cancer Cells to the Oncolytic Virus M1
K Li, H Zhang, J Qiu, Y Lin, J Liang, X Xiao, L Fu, F Wang, J Cai, Y Tan, W Zhu, W Yin, B Lu, F Xing, L Tang, M Yan, J Mai, Y Li, W Chen, P Qiu, X Su, G Gao, PW Tai, J Hu, G Yan |
Molecular Therapy | 2015 |
pH-sensitive oncolytic adenovirus hybrid targeting acidic tumor microenvironment and angiogenesis
JW Choi, SJ Jung, D Kasala, JK Hwang, J Hu, YH Bae, CO Yun |
Journal of Controlled Release | 2015 |
The targeted inhibitory effects of human amniotic fluid stem cells carrying CXCR4 promoter and DAL-1 on non-small cell lung carcinoma growth
L Li, S Li, T Cai, H Wang, X Xie, Z Liu, Y Zhang |
Gene Therapy | 2015 |
Pexa-Vec double agent engineered vaccinia: oncolytic and active immunotherapeutic
CJ Breitbach, K Parato, J Burke, TH Hwang, JC Bell, DH Kirn |
Current Opinion in Virology | 2015 |
Cancer-Causing Viruses and Their Inhibitors
J Yasunaga |
Cancer-Causing Viruses and Their Inhibitors | 2014 |
Oncoapoptotic Markers in Oral Cancer: Prognostics and Therapeutic Perspective
A Jain, S Bundela, RP Tiwari, PS Bisen |
Molecular diagnosis & therapy | 2014 |
Combination of bladder cancer-specific oncolytic adenovirus gene therapy with cisplatin on bladder cancer in vitro
L Wang, Y Zhang, J Zhao, E Xiao, J Lu, S Fu, Z Wang |
Tumor Biology | 2014 |
Terapia génica citotóxica para el tratamiento del cáncer cerebral
MA Ayala, M Candolfi |
Neurología Argentina | 2014 |
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
J Heo, T Reid, L Ruo, CJ Breitbach, S Rose, M Bloomston, M Cho, HY Lim, HC Chung, CW Kim, J Burke, R Lencioni, T Hickman, A Moon, YS Lee, MK Kim, M Daneshmand, K Dubois, L Longpre, M Ngo, C Rooney, JC Bell, BG Rhee, R Patt, TH Hwang, DH Kirn |
Nature Medicine | 2013 |
Fiber-substituted Conditionally Replicating Adenovirus Ad5F35 Induces Oncolysis of Human Bladder Cancer Cells in In Vitro Analysis
A Gotoh, H Nagaya, T Kanno, M Tagawa, T Nishizaki |
Urology | 2013 |
Local sustained delivery of oncolytic adenovirus with injectable alginate gel for cancer virotherapy
JW Choi, E Kang, OJ Kwon, TJ Yun, HK Park, PH Kim, SW Kim, JH Kim, CO Yun |
Gene Therapy | 2013 |
Current status of local therapy in malignant gliomas — A clinical review of three selected approaches
TA Juratli, G Schackert, D Krex |
Pharmacology & Therapeutics | 2013 |
Experimental studies on treatment of pancreatic cancer with double-regulated duplicative adenovirus AdTPHre-hEndo carrying human endostatin gene
Y Shan, Y Fang, X Wang, R Jin, Q Zhang, R Andersson |
Pancreatology | 2013 |
An overview of gene therapy in head and neck cancer
A Bali, D Bali, A Sharma |
Indian journal of human genetics | 2013 |
MicroRNA-mediated suppression of oncolytic adenovirus replication in human liver
E Ylösmäki, S Lavilla-Alonso, S Jäämaa, M Vähä-Koskela, T Hällström, A Hemminki, J Arola, H Mäkisalo, K Saksela |
PloS one | 2013 |
MicroRNA-Mediated Suppression of Oncolytic Adenovirus Replication in Human Liver
E Ylösmäki, S Lavilla-Alonso, S Jäämaa, M Vähä-Koskela, T Hällström, A Hemminki, J Arola, H Mäkisalo, K Saksela, KT Jeang |
PloS one | 2013 |
Advances in Cancer Research
SK Das, S Sarkar, R Dash, P Dent, XY Wang, D Sarkar, PB Fisher |
Advances in cancer research | 2012 |
Therapeutic efficacy of an oncolytic adenovirus containing RGD ligand in minor capsid protein IX and Fiber, Δ24DoubleRGD, in an ovarian cancer model
LJ Gamble, H Ugai, M Wang, AV Borovjagin, QL Matthews |
2012 | |
Clinical development of experimental therapies for malignant glioma
NG Rainov, V Heidecke |
Sultan Qaboos University medical journal | 2011 |
Oncolytic adenovirus armed with human papillomavirus E2 gene in combination with radiation demonstrates synergistic enhancements of antitumor efficacy
W Wang, X Xia, S Wang, N Sima, Y Li, Z Han, Q Gao, A Luo, K Li, L Meng, J Zhou, C Wang, K Shen, D Ma |
Cancer Gene Therapy | 2011 |
Effects of nanoparticle coatings on the activity of oncolytic adenovirus–magnetic nanoparticle complexes
N Tresilwised, P Pithayanukul, PS Holm, U Schillinger, C Plank, O Mykhaylyk |
Biomaterials | 2011 |
A Novel CRAd in Combination With Cisplatin Enhanced the Antitumor Efficacy in Ovarian Cancer :
B Zhang, Y Liu, P Zhang, Y Wei, X Yin, J Zheng |
International Journal of Gynecological Cancer | 2011 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Fiber mediated receptor masking in non-infected bystander cells restricts adenovirus cell killing effect but promotes adenovirus host co-existence
J Rebetz, M Na, C Su, B Holmqvist, A Edqvist, C Nyberg, B Widegren, LG Salford, HO Sjögren, N Arnberg, Q Qian, X Fan |
PloS one | 2009 |
Gene therapy of benign gynecological diseases
MH Hassan, EE Othman, D Hornung, A Al-Hendy |
Advanced Drug Delivery Reviews | 2009 |
Potent antitumor activity of double-regulated oncolytic adenovirus-mediated ST13 for colorectal cancer
DB Yu, SY Zhong, M Yang, YG Wang, QJ Qian, S Zheng, XY Liu |
Cancer Science | 2009 |
Oncolytic gene therapy for canine cancers: teaching old dog viruses new tricks
M Arendt, L Nasir, IM Morgan |
Veterinary and Comparative Oncology | 2009 |
Fiber Mediated Receptor Masking in Non-Infected Bystander Cells Restricts Adenovirus Cell Killing Effect but Promotes Adenovirus Host Co-Existence
J Rebetz, M Na, C Su, B Holmqvist, A Edqvist, C Nyberg, B Widegren, LG Salford, HO Sjögren, N Arnberg, Q Qian, X Fan, MG Masucci |
PloS one | 2009 |
Reproductive Endocrinology
PJ Chedrese |
2009 | |
Potent antitumor activity of double‐regulated oncolytic adenovirus‐mediated ST13 for colorectal cancer
Yu DB, Zhong SY, Yang M, Wang YG, Qian QJ, Zheng S, Liu XY |
Cancer Science | 2009 |
Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy
KF Hsu, CL Wu, SC Huang, JL Hsieh, YS Huang, YF Chen, MR Shen, WJ Chung, CY Chou, AL Shiau |
Cancer Gene Therapy | 2008 |
Inhibition of renal cancer cell growth in vitro and in vivo with oncolytic adenovirus armed short hairpin RNA targeting Ki-67 encoding mRNA
JN Zheng, DS Pei, LJ Mao, XY Liu, DD Mei, BF Zhang, Z Shi, RM Wen, XQ Sun |
Cancer Gene Therapy | 2008 |
Replication competent Semliki Forest virus prolongs survival in experimental lung cancer
AM Määttä, K Mäkinen, A Ketola, T Liimatainen, FN Yongabi, M Vähä-Koskela, R Pirinen, O Rautsi, R Pellinen, A Hinkkanen, J Wahlfors |
International Journal of Cancer | 2008 |
Principles of Molecular Oncology
MH Bronchud, MA Foote, G Giaccone, O Olopade, P Workman |
2008 | |
Carboxypeptidase G2-based gene-directed enzyme–prodrug therapy: a new weapon in the GDEPT armoury
D Hedley, L Ogilvie, C Springer |
Nature Reviews Cancer | 2007 |
Midkine Promoter-Based Conditionally Replicative Adenovirus for Targeting Midkine-Expressing Human Bladder Cancer Model
S Terao, T Shirakawa, S Kubo, A Bishunu, SJ Lee, K Goda, M Tsukuda, K Hamada, M Tagawa, A Takenaka, M Fujisawa, A Gotoh |
Urology | 2007 |
p53-expressing conditionally replicative adenovirus CNHK500-p53 against hepatocellular carcinoma in vitro
HC Zhao, Q Zhang, Y Yang, MQ Lu, H Li, C Xu, GH Chen |
World journal of gastroenterology : WJG | 2007 |
Pharmacodynamics of non-replicating viruses, bacteriocins and lysins
JJ Bull, RR Regoes |
Proceedings. Biological sciences / The Royal Society | 2006 |
Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak
I Schuffenecker, I Iteman, A Michault, S Murri, L Frangeul, MC Vaney, R Lavenir, N Pardigon, JM Reynes, F Pettinelli, L Biscornet, L Diancourt, S Michel, S Duquerroy, G Guigon, MP Frenkiel, AC Bréhin, N Cubito, P Desprès, F Kunst, FA Rey, H Zeller, S Brisse |
PLoS Medicine | 2006 |
Oncolytic adenovirus-mediated transfer of the antisense chk2 selectively inhibits tumor growth in vitro and in vivo
G Chen, J Zhou, Q Gao, X Huang, K Li, L Zhuang, M Huang, G Xu, S Wang, Y Lu, D Ma |
Cancer Gene Therapy | 2006 |
Telomeres and telomerase as targets for anticancer drug development
KA Olaussen, K Dubrana, J Domont, JP Spano, L Sabatier, JC Soria |
Critical Reviews in Oncology/Hematology | 2006 |
Gene therapy developments for pancreatic cancer
M Bhattacharyya, NR Lemoine |
Best Practice & Research Clinical Gastroenterology | 2006 |
A Phase I Trial of Intravenous CG7870, a Replication-Selective, Prostate-Specific Antigen–Targeted Oncolytic Adenovirus, for the Treatment of Hormone-Refractory, Metastatic Prostate Cancer
EJ Small, MA Carducci, JM Burke, R Rodriguez, L Fong, L Ummersen, DC Yu, J Aimi, D Ando, P Working, D Kirn, G Wilding |
Molecular Therapy | 2006 |
Gene therapy and uterine leiomyoma: a review
A Al-Hendy, S Salama |
Human Reproduction Update | 2006 |
Drug Discovery and Delivery in the 21st Century
DJ Triggle |
Medical Principles and Practice | 2006 |
Oncolysis of human ovarian cancers by echovirus type 1
DR Shafren, D Sylvester, ES Johansson, IG Campbell, RD Barry |
International Journal of Cancer | 2005 |
Selective Induction of Apoptosis in Melanoma Cells by Tyrosinase Promoter-Controlled CD95 Ligand Overexpression
LF Fecker, CC Geilen, AM Hossini, C Schwarz, H Fechner, DL Bartlett, CE Orfanos, J Eberle |
Journal of Investigative Dermatology | 2005 |
Expression of p53, or targeting towards EGFR, enhances the oncolytic potency of conditionally replicative adenovirus against neuroblastoma
B Geoerger, VW van Beusechem, P Opolon, J Morizet, L Laudani, Y Lecluse, M Barrois, S Idema, J Grill, WR Gerritsen, G Vassal |
The Journal of Gene Medicine | 2005 |
Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression
T Pipiya, H Sauthoff, YQ Huang, B Chang, J Cheng, S Heitner, S Chen, WN Rom, JG Hay |
Gene Therapy | 2005 |
Inhibition of angiogenesis and HGF-cMET-elicited malignant processes in human hepatocellular carcinoma cells using adenoviral vector-mediated NK4 gene therapy
DA Heideman, RM Overmeer, VW van Beusechem, WH Lamers, TB Hakvoort, PJ Snijders, ME Craanen, GJ Offerhaus, CJ Meijer, WR Gerritsen |
Cancer Gene Therapy | 2005 |
The present and future for gene and viral therapy of directly accessible prostate and squamous cell cancers of the head and neck
JS Norris, KL Norris, DH Holman, A El-Zawahry, TE Keane, J Dong, M Tavassoli |
Future Oncology | 2005 |
Molecular Basis of Thyroid Cancer
NR Farid |
2005 | |
Tissue-specific promoters for cancer gene therapy
K Saukkonen, A Hemminki |
Expert Opinion on Biological Therapy | 2004 |
Potent antitumor efficacy of an E1B 55kDa-deficient adenovirus carrying murineendostatin in hepatocellular carcinoma
G Li, J Sham, J Yang, C Su, H Xue, D Chua, L Sun, Q Zhang, Z Cui, M Wu, Q Qian |
International Journal of Cancer | 2004 |
Insertion of an exogenous promoter in the E1A regulatory region of adenovirus does not disturb viral replication despite reduced E1A transcription
L Yu, K Hamada, M Namba, K Kadomatsu, T Muramatsu, S Matsubara, M Tagawa |
Cancer Letters | 2004 |
Development of a novel recombinant adenovirus containing gfp–zeocin fusion expression cassette for conditional replication in p53-deficient human tumor cells
B Hu, MN Joshua, C Dong, Y Qi |
Journal of Virological Methods | 2004 |
Diagnosis and Management of Ovarian Disorders
AB Copperman, T Mukherjee, NG Kase |
Diagnosis and Management of Ovarian Disorders | 2004 |
Viral Therapy of Human Cancers: Improving Natural Oncolytic Properties by Genetic Engineering
C Springfeld, A Fielding, KW Peng, E Galanis, S Russell, R Cattaneo |
Viral Therapy of Human Cancers: Improving Natural Oncolytic Properties by Genetic Engineering | 2004 |
An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency
TC Liu, G Hallden, Y Wang, G Brooks, J Francis, N Lemoine, D Kirn |
Molecular Therapy | 2004 |
Adenoviruses: Model and Vectors in Virus-Host Interactions
W Doerfler, P Böhm |
2004 | |
A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the alpha-fetoprotein promoter
M Tomizawa, L Yu, A Wada, T Tamaoki, K Kadomatsu, T Muramatsu, S Matsubara, K Watanabe, M Ebara, H Saisho, S Sakiyama, M Tagawa |
British Journal of Cancer | 2003 |
An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacy
ZL ZHANG, WG ZOU, CX LUO, BH LI, JH WANG, LY SUN, QJ QIAN, XY LIU |
Cell Research | 2003 |
Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type I mutant in a mouse model
A Nawa, N Nozawa, F Goshima, T Nagasaka, F Kikkawa, Y Niwa, T Nakanishi, K Kuzuya, Y Nishiyama |
Gynecologic Oncology | 2003 |
Adenovirus E1a protein enhances the cytotoxic effects of the herpes thymidine kinase-ganciclovir system
C Parada, JH Losa, J Guinea, V Sánchez-Arévalo, VF Soria, L Alvarez-Vallina, R Sánchez-Prieto, SR Cajal |
Cancer Gene Therapy | 2003 |
A promoter region of the midkine gene that is frequently expressed in human hepatocellular carcinoma can activate a suicide gene as effectively as the α-fetoprotein promoter
M Tomizawa, L Yu, A Wada, T Tamaoki, K Kadomatsu, T Muramatsu, S Matsubara, K Watanabe, M Ebara, H Saisho, S Sakiyama, M Tagawa |
British Journal of Cancer | 2003 |
Enhanced antitumor effect of combined replicative adenovirus and nonreplicative adenovirus expressing interleukin-12 in an immunocompetent mouse model
Y Nagayama, K Nakao, H Mizuguchi, T Hayakawa, M Niwa |
Gene Therapy | 2003 |
Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model
VK Gupta, JO Park, T Kurihara, A Koons, HJ Mauceri, NT Jaskowiak, DW Kufe, RR Weichselbaum, MC Posner |
Gene Therapy | 2003 |
Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors
VW van Beusechem, DC Mastenbroek, PB van Doel, ML Lamfers, J Grill, T Würdinger, HJ Haisma, HM Pinedo, WR Gerritsen |
Gene Therapy | 2003 |
54. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe
HG Bender, P Dall |
2003 | |
Local Therapies for Glioma Present Status and Future Developments
M Westphal, JC Tonn, Z Ram |
2003 | |
Encyclopedia of Cancer
G Sgouros |
Encyclopedia of Cancer | 2002 |
Gene therapy for lung neoplasms
SM Albelda, R Wiewrodt, DH Sterman |
Clinics in Chest Medicine | 2002 |
Adenoviruses in Oncology
A Hemminki, RD Alvarez |
BioDrugs | 2002 |
Non-invasive in vivo monitoring of trackable viruses expressing soluble marker peptides
KW Peng, S Facteau, T Wegman, D O'Kane, SJ Russell |
Nature Medicine | 2002 |
Differential Susceptibility of Pediatric Sarcoma Cells to Oncolysis by Conditionally Replication-Competent Herpes Simplex Viruses
NS Bharatan, MA Currier, TP Cripe |
Journal of Pediatric Hematology/Oncology | 2002 |
Oncolytic Herpes Simplex Virus (G207) Therapy
T Todo, MI Ebright, Y Fong, SD Rabkin |
2002 | |
Oncolytic Viruses
LK Hawkins, D Kirn |
2002 | |
Reovirus Therapy of Ras-Associated Cancers
PW Lee |
2002 | |
Adenoviral Vectors for Gene Therapy
D Kirn |
Adenoviral Vectors for Gene Therapy | 2002 |
Gene Therapy of Cancer
IV Lebedeva, CA Stein |
Gene Therapy of Cancer | 2002 |
Gene Therapy in Lung Disease
K Amin |
Gene Therapy in Lung Disease | 2002 |
Cytolytic viruses as potential anti-cancer agents
CJ Ring |
Journal of General Virology | 2002 |
Oncolytic biotherapy: a novel therapeutic plafform
Lynda K Hawkins, Nick R Lemoine, David Kirn |
The Lancet Oncology | 2002 |
A System for Small-Molecule Control of Conditionally Replication-Competent Adenoviral Vectors
H Chong, A Ruchatz, T Clackson, VM Rivera, RG Vile |
Molecular Therapy | 2002 |
Adenoviral Vectors with E1A Regulated by Tumor-Specific Promoters Are Selectively Cytolytic for Breast Cancer and Melanoma
L Zhang, H Akbulut, Y Tang, X Peng, G Pizzorno, E Sapi, S Manegold, A Deisseroth |
Molecular Therapy | 2002 |
Transcriptional targeting of conditionally replicating adenovirus to dividing endothelial cells
MJ Savontaus, BV Sauter, TG Huang, SL Woo |
Gene Therapy | 2002 |
Manufacturing of Gene Therapeutics
G Subramanian |
2002 | |
Enhanced antitumor efficacy of a herpes simplex virus mutant isolated by genetic selection in cancer cells
S Taneja, J MacGregor, S Markus, S Ha, I Mohr |
Proceedings of the National Academy of Sciences | 2001 |
Wild-Type Adenovirus Decreases Tumor Xenograft Growth, but Despite Viral Persistence Complete Tumor Responses Are Rarely Achieved—Deletion of the Viral E1b-19-kD Gene Increases the Viral Oncolytic Effect
D Harrison, H Sauthoff, S Heitner, J Jagirdar, WN Rom, JG Hay |
Human Gene Therapy | 2001 |
Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): results of Phase I and II trials
D Kirn |
Expert Opinion on Biological Therapy | 2001 |
Gene therapy for high grade gliomas
JB Alavi, SL Eck |
Expert Opinion on Biological Therapy | 2001 |
Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial
T Reid, E Galanis, J Abbruzzese, D Sze, J Andrews, L Romel, M Hatfield, J Rubin, D Kirn |
Gene Therapy | 2001 |
Gene delivery from the E3 region of replicating human adenovirus: evaluation of the ADP region
LK Hawkins, TW Hermiston |
Gene Therapy | 2001 |
Gene delivery from the E3 region of replicating human adenovirus: evaluation of the E3B region
LK Hawkins, T Hermiston |
Gene Therapy | 2001 |
Oncolytic viruses and cancer therapy
K L Norman, F Farassati, P W Lee |
Cytokine & Growth Factor Reviews | 2001 |
Variation in Adenovirus Receptor Expression and Adenovirus Vector-Mediated Transgene Expression at Defined Stages of the Cell Cycle
MA Seidman, SM Hogan, RL Wendland, S Worgall, RG Crystal, PL Leopold |
Molecular Therapy | 2001 |
A Complex Adenovirus Vector That Delivers FASL–GFP with Combined Prostate-Specific and Tetracycline-Regulated Expression
S Rubinchik, D Wang, H Yu, F Fan, M Luo, JS Norris, J Dong |
Molecular Therapy | 2001 |
Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy
ES Lambright, K Amin, R Wiewrodt, SD Force, M Lanuti, KJ Propert, L Litzky, LR Kaiser, SM Albelda |
Gene Therapy | 2001 |
Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?
D Kirn |
Gene Therapy | 2001 |
Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity
J Nemunaitis, C Cunningham, A Buchanan, A Blackburn, G Edelman, P Maples, G Netto, A Tong, B Randlev, S Olson, D Kirn |
Gene Therapy | 2001 |
Intravascular injections of a conditional replicative adenovirus (adl118) prevent metastatic disease in human breast carcinoma xenografts
A Fabra, C Parada, A Vinyals, PM Duque, V Fernandez, R Sanchez-Prieto, SR Cajal |
Gene Therapy | 2001 |
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics
MA Kay, JC Glorioso, L Naldini |
Nature Medicine | 2001 |
Systemic therapy of myeloma xenografts by an attenuated measles virus
KW Peng, GJ Ahmann, L Pham, PR Greipp, R Cattaneo, SJ Russell |
Blood | 2001 |
Live attenuated measles virus induces regression of human lymphoma xenografts in immunodeficient mice
D Grote, SJ Russell, TI Cornu, R Cattaneo, R Vile, GA Poland, AK Fielding |
Blood | 2001 |
Prodrug-activating systems in suicide gene therapy
CJ Springer, I Niculescu-Duvaz |
Journal of Clinical Investigation | 2000 |
Immunomodulation of cancer: potential use of selectively replicating agents
S Agha-Mohammadi, MT Lotze |
Journal of Clinical Investigation | 2000 |
Regulatable systems: applications in gene therapy and replicating viruses
S Agha-Mohammadi, MT Lotze |
Journal of Clinical Investigation | 2000 |
Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen
T Kurihara, DE Brough, I Kovesdi, DW Kufe |
Journal of Clinical Investigation | 2000 |
Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
D Hanahan, G Bergers, E Bergsland |
Journal of Clinical Investigation | 2000 |
Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer
T Hermiston |
Journal of Clinical Investigation | 2000 |
Conditionally replicative adenoviral vectors for cancer gene therapy
J Gómez, DT Curiel |
The Lancet Oncology | 2000 |
Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer
D Kirn |
Oncogene | 2000 |
Spatial and temporal control of gene therapy using ionizing radiation
T Kurihara, DE Brough, I Kovesdi, DW Kufe |
Nature Medicine | 1995 |