Beckwith-Wiedemann syndrome: imprinting in clusters revisited
Eamonn R. Maher, Wolf Reik
Eamonn R. Maher, Wolf Reik
Published February 1, 2000
Citation Information: J Clin Invest. 2000;105(3):247-252. https://doi.org/10.1172/JCI9340.
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Beckwith-Wiedemann syndrome: imprinting in clusters revisited

Abstract

Authors

Eamonn R. Maher, Wolf Reik

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Figure 1

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The imprinting cluster on human chromosome 11p15.5. The distal breakpoi...
The imprinting cluster on human chromosome 11p15.5. The distal breakpoint cluster region (BWSCR1) is indicated. Breakpoints within BWSCR1 disrupt KvLQT1. Solid red symbols indicate allelic silencing; green/white symbols indicate allelic transcription. The imprinting status of the INS (insulin) gene has not been defined in humans. Further details are included in the text.