Out of the frying pan: dietary saturated fat influences nonalcoholic fatty liver disease
Elizabeth Parks,1 Hannele Yki-Järvinen,2 and Meredith Hawkins3
1Department of Nutrition and Exercise Physiology, and Division of Gastroenterology and Hepatology, University of Missouri School of Medicine, Columbia, Missouri, USA.
2Department of Medicine, University of Helsinki, and Minerva Foundation Institute for Medical Research, Helsinki, Finland.
3Department of Medicine, Division of Endocrinology, and Diabetes Research Center, Albert Einstein College of Medicine, New York, New York, USA.
Address correspondence to: Meredith Hawkins, Albert Einstein College of Medicine, Belfer 709, 1300 Morris Park Avenue, Bronx, New York 10461, USA. Phone: 718.430.3186; E-mail: meredith.hawkins@einstein.yu.edu.
Find articles by Parks, E. in: JCI | PubMed | Google Scholar
1Department of Nutrition and Exercise Physiology, and Division of Gastroenterology and Hepatology, University of Missouri School of Medicine, Columbia, Missouri, USA.
2Department of Medicine, University of Helsinki, and Minerva Foundation Institute for Medical Research, Helsinki, Finland.
3Department of Medicine, Division of Endocrinology, and Diabetes Research Center, Albert Einstein College of Medicine, New York, New York, USA.
Address correspondence to: Meredith Hawkins, Albert Einstein College of Medicine, Belfer 709, 1300 Morris Park Avenue, Bronx, New York 10461, USA. Phone: 718.430.3186; E-mail: meredith.hawkins@einstein.yu.edu.
Find articles by Yki-Järvinen, H. in: JCI | PubMed | Google Scholar
1Department of Nutrition and Exercise Physiology, and Division of Gastroenterology and Hepatology, University of Missouri School of Medicine, Columbia, Missouri, USA.
2Department of Medicine, University of Helsinki, and Minerva Foundation Institute for Medical Research, Helsinki, Finland.
3Department of Medicine, Division of Endocrinology, and Diabetes Research Center, Albert Einstein College of Medicine, New York, New York, USA.
Address correspondence to: Meredith Hawkins, Albert Einstein College of Medicine, Belfer 709, 1300 Morris Park Avenue, Bronx, New York 10461, USA. Phone: 718.430.3186; E-mail: meredith.hawkins@einstein.yu.edu.
Find articles by Hawkins, M. in: JCI | PubMed | Google Scholar
First published January 23, 2017 - More info
J Clin Invest. 2017;127(2):454–456. doi:10.1172/JCI92407.
Copyright © 2017, American Society for Clinical Investigation
Nonalcoholic fatty liver disease (NAFLD) is characterized by excess accumulation of fat in the liver. In some cases, NAFLD is also accompanied by insulin resistance, resulting in metabolic dysfunction. Dietary fat content probably influences both NAFLD and insulin resistance; however, the immediate effects of fat consumption have not been fully explored. In this issue of the
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