MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes

Original citation: J Clin Invest. 2014;124(10):4305–4319. doi:10.1172/JCI77116.

Citation for this corrigendum: J Clin Invest. 2016;126(4):1606. doi:10.1172/JCI86573.

In the process of transferring the miR-182-flox and LSL-miR-182 mice to the Jackson Laboratory, the authors realized that the description of how the LSL-miR-182 mice were generated in the manuscript contained an error. Although the miR-182-flox mice were generated by crossing the mice to a flpO deleter strain to delete the Neo cassette, as was stated in the Methods section, the R26-LSL-miR-182 mice were not crossed to a deleter strain. Instead, the R26-LSL-miR-182 mice that were utilized in this work retained the Neo cassette. Two corrected sentences for the Methods section are below.

Chimeric males were mated to WT C57BL/6 females to generate heterozygotes. These mice were subsequently crossed to a flpO deleter strain to excise the frt-Neo-frt cassette to generate miR-182–flox mice.

The R26-LSL-miR-182 mice that were utilized in this work retained the Neo cassette.

The authors regret the error.

Footnotes

See the related article beginning on page 4305.