Usage Information
Citation Information: J Clin Invest. 2016;126(8):2775-2782. https://doi.org/10.1172/JCI84421.
Abstract
The traditional view of genome organization has been upended in the last decade with the discovery of vast amounts of non–protein-coding transcription. After initial concerns that this “dark matter” of the genome was transcriptional noise, it is apparent that a subset of these noncoding RNAs are functional. Long noncoding RNA (lncRNA) genes resemble protein-coding genes in several key aspects, and they have myriad molecular functions across many cellular pathways and processes, including oncogenic signaling. The number of lncRNA genes has recently been greatly expanded by our group to triple the number of protein-coding genes; therefore, lncRNAs are likely to play a role in many biological processes. Based on their large number and expression specificity in a variety of cancers, lncRNAs are likely to serve as the basis for many clinical applications in oncology.
Authors
Joseph R. Evans, Felix Y. Feng, Arul M. Chinnaiyan
Usage data is cumulative from December 2018 through December 2019.
| Usage | JCI | PMC |
|---|---|---|
| Text version | 1,082 | 196 |
| 217 | 200 | |
| Figure | 151 | 0 |
| Supplemental data | 0 | 67 |
| Citation downloads | 30 | 0 |
| Totals | 1,480 | 463 |
| Total Views | 1,943 | |
Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.
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Copyright © 2019 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)