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Citations to this article

Airway remodeling in asthma
Jack A. Elias, … , Geoffrey Chupp, Robert J. Homer
Jack A. Elias, … , Geoffrey Chupp, Robert J. Homer
Published October 15, 1999
Citation Information: J Clin Invest. 1999;104(8):1001-1006. https://doi.org/10.1172/JCI8124.
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Airway remodeling in asthma

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Abstract

Authors

Jack A. Elias, Zhou Zhu, Geoffrey Chupp, Robert J. Homer

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Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1968 1944 Total
Citations: 3 5 12 4 15 11 12 14 13 16 17 23 12 15 27 21 26 27 32 31 17 31 28 25 25 12 1 1 1 1 478
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Inhibition of airway inflammation and remodeling by sitagliptin in murine chronic asthma
MA Nader
International Immunopharmacology 2015
Mesenchymal stem cells and serelaxin synergistically abrogate established airway fibrosis in an experimental model of chronic allergic airways disease
SG Royce, M Shen, KP Patel, BM Huuskes, SD Ricardo, CS Samuel
Stem Cell Research 2015
Study of the effect of anti-IgE (omalizumab) on serum level of matrix metalloproteinase-9 as a marker of remodeling in severe asthmatic patients
N Affara, A Refaat, M Fathi
Egyptian Journal of Chest Diseases and Tuberculosis 2015
Effect of treatment with inhaled corticosteroid on serum periostin levels in asthma: Effect of inhaled steroids on asthma
M Hoshino, J Ohtawa, K Akitsu
Respirology 2015
Bronchial hyperresponsiveness
J Borak, RY Lefkowitz
Occupational Medicine 2015
Central role of IL-17/Th17 immune responses and the gut microbiota in the pathogenesis of intestinal fibrosis:
S Ray, CD Salvo, TT Pizarro
Current Opinion in Gastroenterology 2014
Cell biology of disease: The cell biology of asthma
DJ Erle, D Sheppard
The Journal of Cell Biology 2014
Is Chronic Asthma Associated with Shorter Leukocyte Telomere Length at Midlife?
DW Belsky, I Shalev, MR Sears, RJ Hancox, HL Harrington, R Houts, TE Moffitt, K Sugden, B Williams, R Poulton, A Caspi
American journal of respiratory and critical care medicine 2014
Application of vitamin E to antagonize SWCNTs-induced exacerbation of allergic asthma
J Li, L Li, H Chen, Q Chang, X Liu, Y Wu, C Wei, R Li, JK Kwan, KL Yeung, Z Xi, Z Lu, X Yang
Scientific Reports 2014
Interleukin-20 Promotes Airway Remodeling in Asthma
W Gong, X Wang, Y Zhang, J Hao, C Xing, Q Chu, G Wang, J Zhao, J Wang, Q Dong, T Liu, Y Zhang, L Dong
Inflammation 2014
ADAM metallopeptidase domain 33 (ADAM33): a promising target for asthma
P Tripathi, S Awasthi, P Gao
Mediators of Inflammation 2014
Lung Remodeling in a Mouse Model of Asthma Involves a Balance between TGF-β1 and BMP-7
CL Stumm, E Halcsik, RG Landgraf, NO Camara, MC Sogayar, S Jancar
PloS one 2014
HMGB1 contributes to allergen-induced airway remodeling in a murine model of chronic asthma by modulating airway inflammation and activating lung fibroblasts
C Hou, J Kong, Y Liang, H Huang, H Wen, X Zheng, L Wu, Y Chen
Cellular and Molecular Immunology 2014
Cystic fibrosis airway epithelium remodelling: involvement of inflammation
D Adam, J Roux-Delrieu, E Luczka, A Bonnomet, J Lesage, JC Mérol, M Polette, M Abély, C Coraux
The Journal of Pathology 2014
Non-anticoagulant derivatives of heparin for the management of asthma: distant dream or close reality?
MD Shastri, GM Peterson, N Stewart, SS Sohal, RP Patel
Expert Opinion on Investigational Drugs 2014
Changing face of β2-adrenergic and muscarinic receptor therapies in asthma
NV Wasilewski, MD Lougheed, JT Fisher
Current Opinion in Pharmacology 2014
Characterization of a novel model incorporating airway epithelial damage and related fibrosis to the pathogenesis of asthma
SG Royce, KP Patel, CS Samuel
Laboratory Investigation 2014
The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice
X Ma, X Ma, Z Ma, Z Sun, W Yu, J Wang, F Li, J Ding
Evidence-Based Complementary and Alternative Medicine 2014
Expression of Airway Remodeling Proteins in Mast Cell Activated by TGF-β Released in OVA-Induced Allergic Responses and Their Inhibition by Low-Dose Irradiation or 8-oxo-dG
GU Hong, NG Kim, JY Ro
Radiation Research 2014
Leukotriene receptor antagonists pranlukast and montelukast for treating asthma
H Matsuse, S Kohno
Expert Opinion on Pharmacotherapy 2014
Factors Contributing to an Accelerated Decline in Pulmonary Function in Asthma
Y Kanemitsu, H Matsumoto, M Mishima, KH Group
Allergology international : official journal of the Japanese Society of Allergology 2014
Characterization of reactive nitrogen species in allergic asthma
L Zuo, MS Koozechian, LL Chen
Annals of Allergy, Asthma & Immunology 2014
Frequency dependence of capnography in anesthetized rabbits
I Ioan, B Demoulin, C Duvivier, AL Leblanc, C Bonabel, F Marchal, C Schweitzer, S Varechova
Respiratory Physiology & Neurobiology 2014
Molecular interaction network and pathway studies of ADAM33 potentially relevant to asthma
S Vishweswaraiah, AM Veerappa, PA Mahesh, BS Jayaraju, CS Krishnarao, NB Ramachandra
Annals of Allergy, Asthma & Immunology 2014
A genome-wide association study identifies susceptibility loci of silica-related pneumoconiosis in Han Chinese
M Chu, X Ji, W Chen, R Zhang, C Sun, T Wang, C Luo, J Gong, M Zhu, J Fan, Z Hou, J Dai, G Jin, T Wu, F Chen, Z Hu, C Ni, H Shen
Human Molecular Genetics 2014
IL-10 and Regulatory T Cells Cooperate in Allergen-Specific Immunotherapy To Ameliorate Allergic Asthma
L Bohm, J Maxeiner, H Meyer-Martin, S Reuter, S Finotto, M Klein, H Schild, E Schmitt, T Bopp, C Taube
Journal of immunology (Baltimore, Md. : 1950) 2014
Lung Remodeling in a Mouse Model of Asthma Involves a Balance between TGF-β1 and BMP-7
CL Stumm, E Halcsik, RG Landgraf, NO Camara, MC Sogayar, S Jancar, B Ryffel
PloS one 2014
Mitochondrial Function in Lung Health and Disease
V Natarajan, NL Parinandi
2014
Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor- 1 in airway fibroblasts in asthma
R Firszt, D Francisco, TD Church, JM Thomas, JL Ingram, M Kraft
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2013
STAT6 controls the number of regulatory T cells in vivo, thereby regulating allergic lung inflammation
NJ Dorsey, SP Chapoval, EP Smith, J Skupsky, DW Scott, AD Keegan
Journal of immunology (Baltimore, Md. : 1950) 2013
Identification of Genes Expressed by Human Airway Eosinophils after an In Vivo Allergen Challenge
S Esnault, EA Kelly, EA Schwantes, LY Liu, LP DeLain, JA Hauer, YA Bochkov, LC Denlinger, JS Malter, SK Mathur, NN Jarjour, PA Stumbles
PloS one 2013
Multi-scale computational models of the airways to unravel the pathophysiological mechanisms in asthma and chronic obstructive pulmonary disease (AirPROM)
KS Burrowes, JD Backer, R Smallwood, PJ Sterk, I Gut, R Wirix-Speetjens, S Siddiqui, J Owers-Bradley, J Wild, D Maier, C Brightling
Interface Focus 2013
The effects of nociceptin peptide (N/OFQ)–receptor (NOP) system activation in the airways
SR Singh, N Sullo, B D’Agostino, CE Brightling, DG Lambert
Peptides 2013
Sevoflurane suppresses tumour necrosis factor- -induced inflammatory responses in small airway epithelial cells after anoxia/reoxygenation
K Watanabe, C Iwahara, H Nakayama, K Iwabuchi, T Matsukawa, K Yokoyama, K Yamaguchi, Y Kamiyama, E Inada
British Journal of Anaesthesia 2013
Extra domain-A fibronectin is necessary for the development of nasal remodeling in chronic allergen-induced rhinitis
N Hirshoren, M Kohan, M Assayag, T Neuman, F Vernea, A Muro, R Eliashar, N Berkman
Annals of Allergy, Asthma & Immunology 2013
Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids
Y Kanemitsu, H Matsumoto, K Izuhara, Y Tohda, H Kita, T Horiguchi, K Kuwabara, K Tomii, K Otsuka, M Fujimura, N Ohkura, K Tomita, A Yokoyama, H Ohnishi, Y Nakano, T Oguma, S Hozawa, T Nagasaki, I Ito, T Oguma, H Inoue, T Tajiri, T Iwata, Y Izuhara, J Ono, S Ohta, M Tamari, T Hirota, T Yokoyama, A Niimi, M Mishima
Journal of Allergy and Clinical Immunology 2013
Ultrastructural changes of airway in murine models of allergy and diet-induced metabolic syndrome
GD Leishangthem, U Mabalirajan, VP Singh, A Agrawal, B Ghosh, AK Dinda
ISRN Allergy 2013
Evaluation of the Effects of Caffeic Acid Phenethyl Ester on Prostaglandin E2 and Two Key Cytokines Involved in Bleomycin-induced Pulmonary Fibrosis
A Larki-Harchegani, AA Hemmati, A Arzi, M Ghafurian-Boroojerdnia, S Shabib, MR Zadkarami, S Esmaeilzadeh
Iranian Journal of Basic Medical Sciences 2013
Calcium Signaling In Airway Smooth Muscle Cells
YX Wang
2013
Perspectives in inflammation biology
ER Banerjee
2013
An Essential Regulatory Role of Downstream of Kinase-1 in the Ovalbumin-Induced Murine Model of Asthma
CM Lee, ID Jung, KT Noh, JS Lee, JW Park, DR Heo, JH Park, JH Chang, IW Choi, JS Kim, YK Shin, SJ Park, MK Han, CG Lee, WK Cho, YM Park, G Das
PloS one 2012
Superoxide Dismutase 3 Controls Adaptive Immune Responses and Contributes to the Inhibition of Ovalbumin-Induced Allergic Airway Inflammation in Mice
MJ Kwon, YJ Jeon, KY Lee, TY Kim
Antioxidants & Redox Signaling 2012
Mechanisms of Remodeling in Asthmatic Airways
A Shifren, C Witt, C Christie, M Castro
Journal of allergy 2012
From expression pattern to genetic association in asthma and asthma-related phenotypes
VT Vaillancourt, M Bordeleau, M Laviolette, C Laprise
BMC Research Notes 2012
Influence of inhaled beclomethasone and montelukast on airway remodeling in mice
RR Aziz, NY Helaly, KR Zalata, NM Gameil
Inflammopharmacology 2012
Long-term use of doxycycline can improve chronic asthma and possibly remodeling: the result of a pilot observation
P Bhattacharyya, R Paul, P Bhattacharjee, A Ghosh, R Dey, M Ghosh, M Sharma
Journal of asthma and allergy 2012
Medicinal Plants: Biodiversity and Drugs
M Fawzi
Medicinal Plants: Biodiversity and Drugs 2012
Antifibrosis effects of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. 1eaf in a rat model of bleomycin-induced pulmonary fibrosis: Effect of TAL on cytokine expression
Y Yang, Y Huang, C Huang, X Lv, L Liu, Y Wang, J Li
Journal of Pharmacy and Pharmacology 2012
Dynamic visco-elastic buckling analysis of an in vitro airway model: prediction of circumferential and axial buckling mode numbers
K Bando, K Ohba
Journal of Biorheology 2012
Exhaled breath condensate MMP-9 level and its relationship wıth asthma severity and interleukin-4/10 levels in children
GB Karakoc, A Yukselen, M Yilmaz, DU Altintas, SG Kendirli
Annals of Allergy, Asthma & Immunology 2012
Heterogeneity in the responses of human lung mast cells to stem cell factor
A Lewis, J Wan, B Baothman, PN Monk, SK Suvarna, PT Peachell
Clinical & Experimental Allergy 2012
MAPK regulation of IL-4/IL-13 receptors contributes to the synergistic increase in CCL11/eotaxin-1 in response to TGF-β1 and IL-13 in human airway fibroblasts
X Zhou, H Hu, S Balzar, JB Trudeau, SE Wenzel
Journal of immunology (Baltimore, Md. : 1950) 2012
Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same disease
A Soltani, HK Muller, SS Sohal, DW Reid, S Weston, R Wood-Baker, EH Walters
Histopathology 2012
Hypertrophic Airway Smooth Muscle Mass Correlates with Increased Airway Responsiveness in a Murine Model of Asthma
PJ Plant, ML North, A Ward, M Ward, N Khanna, J Correa, JA Scott, J Batt
American journal of respiratory cell and molecular biology 2012
Genetically manipulated mouse models of lung disease: potential and pitfalls
RM Baron, AJ Choi, CA Owen, AM Choi
American journal of physiology. Lung cellular and molecular physiology 2012
Lung fibroblasts regulate dendritic cell trafficking, airway inflammation and fibrosis, in vivo, through integrin αvβ8-mediated activation of TGF-β
Hideya Kitamura, Stephanie Cambier, Sangeeta Somanath, Tyren Barker, Shunsuke Minagawa, Jennifer Markovics, Amanda Goodsell, Jean Publicover, Louis Reichardt, David Jablons, Paul Wolters, Arthur Hill, James Marks, Jianlong Lou, Jean Francois Pittet, Jack Gauldie, Jody Baron, Stephen Nishimura
Journal of Clinical Investigation 2011
FIZZ2/RELM-β induction and role in pulmonary fibrosis
T Liu, HA Baek, H Yu, HJ Lee, BH Park, M Ullenbruch, J Liu, T Nakashima, YY Choi, GD Wu, MJ Chung, SH Phan
Journal of immunology (Baltimore, Md. : 1950) 2011
IL-13 Induces Skin Fibrosis in Atopic Dermatitis by Thymic Stromal Lymphopoietin
MH Oh, SY Oh, J Yu, AC Myers, WJ Leonard, YJ Liu, Z Zhu, T Zheng
Journal of immunology (Baltimore, Md. : 1950) 2011
Genetically manipulated mouse models of lung disease: potential and pitfalls
RM Baron, AJ Choi, CA Owen, AM Choi
American journal of physiology. Lung cellular and molecular physiology 2011
The Role of Hyaluronan and Hyaluronan Binding Proteins in Human Asthma
J Liang, D Jiang, Y Jung, T Xie, J Ingram, T Church, S Degan, M Leonard, M Kraft, PW Noble
Journal of Allergy and Clinical Immunology 2011
Nitric oxide metabolism in asthma pathophysiology
S Ghosh, SC Erzurum
Biochimica et Biophysica Acta (BBA) - General Subjects 2011
Reversible remodeling of lung tissue during hibernation in the Syrian hamster
F Talaei, MN Hylkema, HR Bouma, AS Boerema, AM Strijkstra, RH Henning, M Schmidt
The Journal of experimental biology 2011
Environmental Tobacco Smoke and Progesterone Alter Lung Inflammation and Mucous Metaplasia in a Mouse Model of Allergic Airway Disease
VL Mitchell, LS Winkle, LJ Gershwin
Clinical Reviews in Allergy & Immunology 2011
Nerve growth factor induces type III collagen production in chronic allergic airway inflammation
A Kılıç, SS Sonar, AO Yildirim, H Fehrenbach, WA Nockher, H Renz
Journal of Allergy and Clinical Immunology 2011
Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury
CG Lee, CA da Silva, CS Cruz, F Ahangari, B Ma, MJ Kang, CH He, S Takyar, JA Elias
Annual Review of Physiology 2011
Treatment of Asthma and Food Allergy With Herbal Interventions From Traditional Chinese Medicine
XM Li
Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine 2011
Impact of obesity on airway and lung parenchyma remodeling in experimental chronic allergic asthma
SA Saraiva, AL Silva, DG Xisto, SC Abreu, JD Silva, PL Silva, TP Teixeira, ER Parra, AL Carvalho, R Annoni, T Mauad, VL Capelozzi, PM Silva, MA Martins, PR Rocco
Respiratory Physiology & Neurobiology 2011
Nitrative stress in inflammatory lung diseases
H Sugiura, M Ichinose
Nitric Oxide 2011
Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects
H Fujita, M Chalubinski, C Rhyner, P Indermitte, N Meyer, R Ferstl, A Treis, E Gomez, A Akkaya, L O’Mahony, M Akdis, CA Akdis
Journal of Allergy and Clinical Immunology 2011
Conjugated linoleic acid (CLA): Is it time to supplement asthma therapy?
R MacRedmond, DR Dorscheid
Pulmonary Pharmacology & Therapeutics 2011
Antifibrosis effects of total glucosides of Danggui–Buxue–Tang in a rat model of bleomycin-induced pulmonary fibrosis
J Gao, Y Huang, P Li, D Xu, J Li, Y Liu, Z Huang, Q Wu, X Shao
Journal of Ethnopharmacology 2011
Asthma morbidity and treatment in children with sickle cell disease
SO Anim, RC Strunk, MR DeBaun
Expert Review of Respiratory Medicine 2011
Mepacrine treatment attenuates allergic airway remodeling segregated from airway inflammation in mice
T Ahmad, U Mabalirajan, K Hasija, B Ghosh, A Agrawal
International Immunopharmacology 2011
The Protease Allergen Pen c 13 Induces Allergic Airway Inflammation and Changes in Epithelial Barrier Integrity and Function in a Murine Model*
JC Chen, JG Chuang, YY Su, BL Chiang, YS Lin, LP Chow
The Journal of biological chemistry 2011
Harnessing opportunities in non-animal asthma research for a 21st-century science
GL Buckland
Drug Discovery Today 2011
Effects of Ascaris suum Extract and Sulfamethoxazole on Allergic Airway Inflammation
ES Cho, BK Park, HY Son
Biomolecules and Therapeutics 2011
Effect of verapamil on bronchial goblet cells of asthma: An experimental study on sensitized animals
MR Khakzad, M Mirsadraee, A Mohammadpour, K Ghafarzadegan, R Hadi, M Saghari
Pulmonary Pharmacology & Therapeutics 2011
Investigation of in vitro and in vivo anti-asthmatic properties of Siphonochilus aethiopicus
G Fouche, N Nieuwenhuizen, V Maharaj, S Rooyen, N Harding, R Nthambeleni, J Jayakumar, F Kirstein, B Emedi, P Meoni
Journal of Ethnopharmacology 2011
Investigating in vivo airway wall mechanics during tidal breathing with optical coherence tomography
C Robertson, SW Lee, YC Ahn, S Mahon, Z Chen, M Brenner, SC George
Journal of Biomedical Optics 2011
The Protease Allergen Pen c 13 Induces Allergic Airway Inflammation and Changes in Epithelial Barrier Integrity and Function in a Murine Model
JC Chen, JG Chuang, YY Su, BL Chiang, YS Lin, LP Chow
The Journal of biological chemistry 2011
Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice
S Miyamoto, N Hattori, T Senoo, Y Onari, H Iwamoto, M Kanehara, N Ishikawa, K Fujitaka, Y Haruta, H Murai, A Yokoyama, N Kohno
American journal of physiology. Lung cellular and molecular physiology 2011
Role of ADAM33 Gene and Associated Single Nucleotide Polymorphisms in Asthma
N Sharma, P Tripathi, S Awasthi
Allergy & Rhinology 2011
Overlap Between Asthma and COPD: Where the Two Diseases Converge
SR Kim, YK Rhee
Allergy, Asthma and Immunology Research 2010
Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c
S Ghavami, MM Mutawe, K Hauff, GL Stelmack, D Schaafsma, P Sharma, KD McNeill, TS Hynes, SK Kung, H Unruh, T Klonisch, GM Hatch, M Los, AJ Halayko
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2010
Alterations in Adenosine Metabolism and Signaling in Patients with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis
Y Zhou, JN Murthy, D Zeng, L Belardinelli, MR Blackburn, M Rojas
PloS one 2010
Asthma and pulmonary arterial hypertension: do they share a key mechanism of pathogenesis?
SI Said, SA Hamidi, LG Bosc
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010
ISO-1, a macrophage migration inhibitory factor antagonist, inhibits airway remodeling in a murine model of chronic asthma
PF Chen, Y Luo, W Wang, J Wang, W Lai, S Hu, KF Cheng, Y Al-Abed
Molecular Medicine 2010
Topley & Wilson's Microbiology and Microbial Infections
PM Pitha, MS Künzi
Topley & Wilson's Microbiology and Microbial Infections 2010
Inflammatory cytokines in allergy and rhinosinusitis
SM Daines, RR Orlandi
Current Opinion in Otolaryngology & Head and Neck Surgery 2010
The role of interleukin-4Rα in the induction of glutamic acid decarboxylase in airway epithelium following acute house dust mite exposure
JA Hirota, A Budelsky, D Smith, B Lipsky, R Ellis, YY Xiang, WY Lu, MD Inman
Clinical & Experimental Allergy 2010
Blockade of cysteinyl leukotriene-1 receptors suppresses airway remodelling in mice overexpressing GATA-3
T Kiwamoto, Y Ishii, Y Morishima, K Yoh, N Kikuchi, N Haraguchi, H Masuko, M Kawaguchi, A Nomura, T Sakamoto, S Takahashi, N Hizawa
Clinical & Experimental Allergy 2010
Airway Wall Structure Assessed by Endobronchial Ultrasonography and Bronchial Hyperresponsiveness in Patients With Asthma
T Kita, M Fujimura, N Kurimoto, T Sone, K Inuzuka, T Hirose, Y Oribe, S Myou, S Nakao
Journal of Bronchology & Interventional Pulmonology 2010
In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse
X Luo, Q Ding, M Wang, Z Li, K Mao, B Sun, Y Pan, Z Wang, YQ Zang, Y Chen
PloS one 2010
Deficiency in the serum-derived hyaluronan-associated protein-hyaluronan complex enhances airway hyperresponsiveness in a murine model of asthma
L Zhu, L Zhuo, K Kimata, E Yamaguchi, H Watanabe, MA Aronica, VC Hascall, K Baba
International Archives of Allergy and Immunology 2010
Airway remodelling in asthma: from benchside to clinical practice
C Bergeron, MK Tulic, Q Hamid
Canadian respiratory journal : journal of the Canadian Thoracic Society 2010
CIGARETTE SMOKE ALTERS TIMP-1 AND MMP-9 LEVELS IN THE BASOLATERAL SECRETIONS OF HUMAN ASTHMATIC BRONCHIAL EPITHELIUM IN VITRO
AM Watson, AS Benton, MC Rose, RJ Freishtat
Journal of Investigative Medicine 2010
Rosen's Emergency Medicine – Concepts and Clinical Practice
DJ Roberts
Rosen's Emergency Medicine – Concepts and Clinical Practice 2010
Mécanotransduction et épithélium bronchoalvéolaire
J Merrien, D Gras, P Robert, P Chanez
Revue des Maladies Respiratoires 2010
A phosphoinositide 3-kinase-γ inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats
X Wei, J Han, Z Chen, B Qi, G Wang, Y Ma, H Zheng, Y Luo, Y Wei, L Chen
Biochemical and Biophysical Research Communications 2010
Up-regulation of cyclin D1 expression in asthma serum-sensitized human airway smooth muscle promotes proliferation via protein kinase Cα
CL Du, YJ Xu, XS Liu, JG Xie, M Xie, ZX Zhang, J Zhang, LF Qiao
Experimental Lung Research 2010
Extracellular acidification stimulates IL-6 production and Ca 2+ mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells
I Ichimonji, H Tomura, C Mogi, K Sato, H Aoki, T Hisada, K Dobashi, T Ishizuka, M Mori, F Okajima
American journal of physiology. Lung cellular and molecular physiology 2010
Altered lymphocyte trafficking and diminished airway reactivity in transgenic mice expressing human MMP-9 in a mouse model of asthma
D Mehra, DI Sternberg, Y Jia, S Canfield, V Lemaitre, T Nkyimbeng, J Wilder, J Sonett, J D'Armiento
American journal of physiology. Lung cellular and molecular physiology 2010
Allergy Frontiers: Future Perspectives
R Pawankar, ST Holgate, LJ Rosenwasser
2010
Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma
R Tachdjian, C Mathias, SA Khatib, PJ Bryce, HS Kim, F Blaeser, BD O'Connor, D Rzymkiewicz, A Chen, MJ Holtzman, GK Hershey, H Garn, H Harb, H Renz, HC Oettgen, TA Chatila
Journal of Experimental Medicine 2009
TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses1
MB Headley, B Zhou, WX Shih, T Aye, MR Comeau, SF Ziegler
Journal of immunology (Baltimore, Md. : 1950) 2009
Regulatory T cells negatively regulate neovasculature of airway remodeling via DLL4-Notch signaling
MT Huang, YS Dai, YB Chou, YH Juan, CC Wang, BL Chiang
Journal of immunology (Baltimore, Md. : 1950) 2009
Altered lymphocyte trafficking and diminished airway reactivity in transgenic mice expressing human MMP-9 in a mouse model of asthma
D Mehra, DI Sternberg, Y Jia, S Canfield, V Lemaitre, T Nkyimbeng, J Wilder, J Sonett, J D'Armiento
American journal of physiology. Lung cellular and molecular physiology 2009
Mechanism of eosinophilic esophagitis
A Mishra
Immunology and Allergy Clinics of North America 2009
Acidic Mammalian Chitinase Regulates Epithelial Cell Apoptosis via a Chitinolytic-Independent Mechanism
D Hartl, CH He, B Koller, CA Silva, Y Kobayashi, CG Lee, RA Flavell, JA Elias
Journal of immunology (Baltimore, Md. : 1950) 2009
IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure
Y Onari, A Yokoyama, Y Haruta, T Nakashima, H Iwamoto, N Hattori, N Kohno
Cell 2009
Regulation of type 1 diabetes, tuberculosis, and asthma by parasites
Z Liu, Q Liu, D Bleich, P Salgame, WC Gause
Journal of Molecular Medicine 2009
MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression
TX Lu, A Munitz, ME Rothenberg
Journal of immunology (Baltimore, Md. : 1950) 2009
Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling
BD Medoff, Y Okamoto, P Leyton, M Weng, BP Sandall, MJ Raher, S Kihara, KD Bloch, P Libby, AD Luster
American journal of respiratory cell and molecular biology 2009
Absence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic models
ER Banerjee, Y Jiang, WR Henderson, Y Latchman, T Papayannopoulou
Experimental Hematology 2009
Depletion of CD8+T cells enhances airway remodelling in a rodent model of asthma
K Tsuchiya, S Isogai, M Tamaoka, N Inase, T Akashi, JG Martin, Y Yoshizawa
Immunology 2009
Tissue inhibitor of metalloproteinase-1 modulates allergic lung inflammation in murine asthma
MF Sands, PJ Ohtake, SD Mahajan, SS Takyar, R Aalinkeel, YV Fang, JW Blume, BA Mullan, DE Sykes, S Lachina, PR Knight, SA Schwartz
Clinical Immunology 2009
Expression and Function of the Inducible Costimulator Ligand B7-H2 in Human Airway Smooth Muscle Cells
K Kajiwara, H Morishima, K Akiyama, Y Yanagihara
Allergology International 2009
Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2–Keap1 signaling
N Sriram, S Kalayarasan, G Sudhandiran
Pulmonary Pharmacology & Therapeutics 2009
Mechanical Properties of the Respiratory System Derived From Morphologic Insight
CM Ionescu, P Segers, RD Keyser
IEEE Transactions on Biomedical Engineering 2009
IMIQUIMOD, A TOLL-LIKE RECEPTOR 7 LIGAND, INHIBITS AIRWAY REMODELLING IN A MURINE MODEL OF CHRONIC ASTHMA
Q Du, LF Zhou, Z Chen, XY Gu, M Huang, KS Yin
Clinical and Experimental Pharmacology and Physiology 2009
Asthma management: Reinventing the wheel in sickle cell disease
CR Morris
American Journal of Hematology 2009
Mechanical compression attenuates normal human bronchial epithelial wound healing
SP Arold, N Malavia, SC George
Respiratory Research 2009
Highlights of the April Issue
S Matalon, KB Adler
American journal of respiratory cell and molecular biology 2009
Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells
S Iwata, S Ito, M Iwaki, M Kondo, T Sashio, N Takeda, M Sokabe, Y Hasegawa, H Kume
European Journal of Pharmacology 2009
Pediatric Asthma: An Integrative Approach to Care
JD Mark
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 2009
Attenuation of allergen-induced airway hyperresponsiveness is mediated by airway regulatory T cells
JT Burchell, ME Wikstrom, PA Stumbles, PD Sly, DJ Turner
American journal of physiology. Lung cellular and molecular physiology 2009
Epithelium-derived chemokines induce airway smooth muscle cell migration
N Takeda, Y Sumi, D Préfontaine, JA Abri, NA Heialy, W Al-Ramli, MC Michoud, JG Martin, Q Hamid
Cell 2009
Host Cell Cytokines Induced by Chlamydia pneumoniae Decrease the Expression of Interstitial Collagens and Fibronectin in Fibroblasts
J Baumert, KH Schmidt, A Eitner, E Straube, J Rödel
Infection and immunity 2009
Assessment of airway hyperreactivity: comparison of forced spirometry and body plethysmography for methacholine challenge tests
F Nensa, W Marek, E Marek, HJ Smith, M Kohlhäufl
European Journal of Medical Research 2009
Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1
JF Alcorn, AS Guala, J der Velden, B McElhinney, CG Irvin, RJ Davis, YM Janssen-Heininger
Journal of cell science 2008
Stem cells in airway smooth muscle: state of the art
J Murphy, R Summer, A Fine
Proceedings of the American Thoracic Society 2008
Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses
C Blanchard, MK Mingler, M McBride, PE Putnam, MH Collins, G Chang, K Stringer, JP Abonia, JD Molkentin, ME Rothenberg
Mucosal Immunology 2008
Cellular and molecular mechanisms of fibrosis
TA Wynn
The Journal of Pathology 2008
IL-13 induces a bronchial epithelial phenotype that is profibrotic
NK Malavia, JD Mih, CB Raub, BT Dinh, SC George
Respiratory Research 2008
Lymphatics in Lung Disease
S El-Chemaly, SJ Levine, J Moss
Annals of the New York Academy of Sciences 2008
c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis
JF Alcorn, J der Velden, AL Brown, B McElhinney, CG Irvin, YM Janssen-Heininger
American journal of respiratory cell and molecular biology 2008
Role of Cilia, Mucus, and Airway Surface Liquid in Mucociliary Dysfunction: Lessons from Mouse Models
MA Mall
Journal of Aerosol Medicine and Pulmonary Drug Delivery 2008
Do two mutually exclusive gene modules define the phenotypic diversity of mammalian smooth muscle?
E Larsson, SE McLean, RP Mecham, P Lindahl, S Nelander
Molecular Genetics and Genomics 2008
Oxidative and Nitrative Stress in Bronchial Asthma
H Sugiura, M Ichinose
Antioxidants & Redox Signaling 2008
Growth Factors Temporally Associate with Airway Responsiveness and Inflammation in Allergen-Exposed Mice
W Ito, M Tanimoto, K Ono, S Mizuno, A Yoshida, H Koga, Y Fuchimoto, N Kondo, Y Tanimoto, K Kiura, K Matsumoto, M Kataoka, T Nakamura, EW Gelfand, A Kanehiro
International Archives of Allergy and Immunology 2008
TGF-β1 as a therapeutic target for pulmonary fibrosis and COPD
HR Kang, JY Lee, CG Lee
Expert Review of Clinical Pharmacology 2008
Suppression of cytokine expression by roflumilast and dexamethasone in a model of chronic asthma
C Herbert, A Hettiaratchi, DC Webb, PS Thomas, PS Foster, RK Kumar
Clinical & Experimental Allergy 2008
2-Methoxyestradiol (2-ME) reduces the airway inflammation and remodeling in an experimental mouse model
S Huerta-Yepez, GJ Baay-Guzman, R Garcia-Zepeda, R Hernandez-Pando, MI Vega, C Gonzalez-Bonilla, B Bonavida
Clinical Immunology 2008
Nitrative stress in refractory asthma
H Sugiura, Y Komaki, A Koarai, M Ichinose
Journal of Allergy and Clinical Immunology 2008
Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma
Q Du, Z Chen, L Zhou, Q Zhang, M Huang, K Yin
Canadian Journal of Physiology and Pharmacology 2008
Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4
Y Ito, M Hirano, N Umemoto, L Zang, Z Wang, T Oka, Y Shimada, Y Nishimura, I Kurokawa, H Mizutani, T Tanaka
BMB Reports 2008
Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures
AS Sabnis, CA Reilly, JM Veranth, GS Yost
American journal of physiology. Lung cellular and molecular physiology 2008
Oral administration of the purple passion fruit peel extract reduces wheeze and cough and improves shortness of breath in adults with asthma
RR Watson, S Zibadi, H Rafatpanah, F Jabbari, R Ghasemi, J Ghafari, H Afrasiabi, LY Foo, R Faridhosseini
Nutrition Research 2008
Inhaled corticosteroid prevents the thickening of airway smooth muscle in murine model of chronic asthma
SY Lee, JS Kim, JM Lee, SS Kwon, KH Kim, HS Moon, JS Song, SH Park, YK Kim
Pulmonary Pharmacology & Therapeutics 2008
Cell types involved in allergic asthma and their use in in vitro models to assess respiratory sensitization
S Verstraelen, K Bloemen, I Nelissen, H Witters, G Schoeters, RV Heuvel
Toxicology in Vitro 2008
Anti-allergic inflammatory effects of hepatocyte growth factor
W Ito, M Takeda, M Tanabe, J Kihara, H Kato, T Chiba, K Yamaguchi, S Ueki, A Kanehiro, H Kayaba, J Chihara
International Archives of Allergy and Immunology 2008
Increased Circulating Fibrocytes in Asthma with Chronic Airflow Obstruction
CH Wang, CD Huang, HC Lin, KY Lee, SM Lin, CY Liu, KH Huang, YS Ko, KF Chung, HP Kuo
American journal of respiratory and critical care medicine 2008
Interleukin 4 receptor is associated with an increase in body mass index in Koreans
E Ha, SH Yang, KI Yoo, IS Chung, MY Lee, JH Bae, JC Seo, JH Chung, DH Shin
Life Sciences 2008
Oral tolerance attenuates changes in in vitro lung tissue mechanics and extracellular matrix remodeling induced by chronic allergic inflammation in guinea pigs
AS Nakashima, CM Prado, T Lanças, VC Ruiz, DI Kasahara, EA Leick-Maldonado, M Dolhnikoff, MA Martins, IF Tibério
Journal of applied physiology 2008
Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures
AS Sabnis, CA Reilly, JM Veranth, GS Yost
American journal of physiology. Lung cellular and molecular physiology 2008
Expression and Regulation of CCR1 by Airway Smooth Muscle Cells in Asthma
P Joubert, S Lajoie-Kadoch, M Welman, S Dragon, S Létuvée, B Tolloczko, AJ Halayko, AS Gounni, K Maghni, Q Hamid
Journal of immunology (Baltimore, Md. : 1950) 2008
Infectious Disease, the Innate Immune Response, and Fibrosis
Alessia Meneghin, MD and Cory M. Hogaboam, PhD
Journal of Clinical Investigation 2007
Cultured lung fibroblasts from ovalbumin-challenged "asthmatic" mice differ functionally from normal
H Sugiura, X Liu, F Duan, S Kawasaki, S Togo, K Kamio, XQ Wang, L Mao, Y Ahn, RF Ertl, TW Bargar, A Berro, TB Casale, SI Rennard
American journal of respiratory cell and molecular biology 2007
Semaphorin 7A plays a critical role in TGF-β 1 –induced pulmonary fibrosis
HR Kang, CG Lee, RJ Homer, JA Elias
Journal of Experimental Medicine 2007
Inhibition of NF-κB Activation Reduces the Tissue Effects of Transgenic IL-13
SP Chapoval, A Al-Garawi, JM Lora, I Strickland, B Ma, PJ Lee, RJ Homer, S Ghosh, AJ Coyle, JA Elias
Journal of immunology (Baltimore, Md. : 1950) 2007
IL-13 regulates cilia loss and foxj1 expression in human airway epithelium
BN Gomperts, LJ Kim, SA Flaherty, BP Hackett
American journal of respiratory cell and molecular biology 2007
Biomedicine & Diseases: Review Eosinophils in the pathogenesis of allergic airways disease
SG Trivedi, CM Lloyd
Cellular and Molecular Life Sciences 2007
Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease
JF Alcorn, LM Rinaldi, EF Jaffe, M Loon, JH Bates, YM Janssen-Heininger, CG Irvin
American journal of respiratory and critical care medicine 2007
Epithelial Cell Proliferation Contributes to Airway Remodeling in Severe Asthma
Cohen L, E X, Tarsi J, Ramkumar T, Horiuchi TK, Cochran R, DeMartino S, Schechtman KB, Hussain I, Holtzman MJ, Castro M
American journal of respiratory and critical care medicine 2007
The Immune Response to Respiratory Syncytial Virus Infection: Friend or Foe?
RC Welliver
Clinical Reviews in Allergy & Immunology 2007
Differential Role of Thymic Stromal Lymphopoietin in the Induction of Airway Hyperreactivity and Th2 Immune Response in Antigen-Induced Asthma with Respect to Natural Killer T Cell Function
Y Nagata, H Kamijuku, M Taniguchi, S Ziegler, K Seino
International Archives of Allergy and Immunology 2007
Tumor necrosis factor-α in severe corticosteroid-refractory asthma
JB Morjaria, KS Babu, R Polosa, ST Holgate
Expert Review of Respiratory Medicine 2007
Animal models of asthma
GR Zosky, PD Sly
Clinical & Experimental Allergy 2007
IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation
P Puccetti, U Grohmann
Nature Reviews Immunology 2007
Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the respiratory tracts of human infants following paramyxovirus infection
MB Elliott, RC Welliver, TS Laughlin, KS Pryharski, NA LaPierre, T Chen, V Souza, NB Terio, GE Hancock
Journal of Medical Virology 2007
Functional lung imaging using hyperpolarized gas MRI
SB Fain, FR Korosec, JH Holmes, R O'Halloran, RL Sorkness, TM Grist
Journal of Magnetic Resonance Imaging 2007
Evidence for airway surface dehydration as the initiating event in CF airway disease
RC Boucher
Journal of Internal Medicine 2007
The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses
A Bellini, S Mattoli
Laboratory Investigation 2007
Stem Cells and Chronic Lung Disease
BN Gomperts, RM Strieter
Annual Review of Medicine 2007
Airway Surface Dehydration in Cystic Fibrosis: Pathogenesis and Therapy
RC Boucher
Annual Review of Medicine 2007
Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma
JK Mansoor, KC Decile, SN Giri, KE Pinkerton, WF Walby, JM Bratt, H Grewal, SB Margolin, ES Schelegle
Pulmonary Pharmacology & Therapeutics 2007
Nickel alterations of TLR2-dependent chemokine profiles in lung fibroblasts are mediated by COX-2
KA Brant, JP Fabisiak
American journal of respiratory cell and molecular biology 2007
The allergic cascade: Review of the most important molecules in the asthmatic lung
K Bloemen, S Verstraelen, RV Heuvel, H Witters, I Nelissen, G Schoeters
Immunology Letters 2007
Association between a TGFβ1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients
SH Kim, HS Park, JW Holloway, HD Shin, CS Park
Respiratory Medicine 2007
Components of airway hyperresponsiveness and their associations with inflammation and remodeling in mice
DS Southam, R Ellis, J Wattie, MD Inman
Journal of Allergy and Clinical Immunology 2007
Bronchial Inflammation and Airway Responses to Deep Inspiration in Asthma and Chronic Obstructive Pulmonary Disease
AM Slats, K Janssen, A Schadewijk, DT van der Plas, R Schot, JG van Aardweg, JC de Jongste, PS Hiemstra, T Mauad, KF Rabe, PJ Sterk
American journal of respiratory and critical care medicine 2007
Studies on the selenoproteome in the cultured cells of lung and trachea by gel electrophoretic techniques
K Bukalis, C Wolf, D Behne, A Kyriakopoulos
Journal of Chromatography A 2007
ETBreceptor polymorphism is associated with airway obstruction
C Taillé, A Guénégou, A Almolki, M Piperaud, B Leynaert, S Vuillaumier, F Neukirch, J Boczkowski, M Aubier, J Benessiano, B Crestani
BMC Pulmonary Medicine 2007
Resistin-like molecule-β is an allergen-induced cytokine with inflammatory and remodeling activity in the murine lung
A Mishra, M Wang, J Schlotman, NM Nikolaidis, CW DeBrosse, ML Karow, ME Rothenberg
American journal of physiology. Lung cellular and molecular physiology 2007
Fibrocytes in lung disease
BN Gomperts, RM Strieter
Journal of leukocyte biology 2007
Optimal management of preschool asthma
C Calogero, PD Sly
Expert Review of Respiratory Medicine 2007
Unc119 Regulates Myofibroblast Differentiation through the Activation of Fyn and the p38 MAPK Pathway
R Vepachedu, MM Gorska, N Singhania, GP Cosgrove, KK Brown, R Alam
Journal of immunology (Baltimore, Md. : 1950) 2007
CD8 + T Cell-Mediated Airway Hyperresponsiveness and Inflammation Is Dependent on CD4 + IL-4 + T Cells
T Koya, N Miyahara, K Takeda, S Matsubara, H Matsuda, C Swasey, A Balhorn, A Dakhama, EW Gelfand
Journal of immunology (Baltimore, Md. : 1950) 2007
Regulation of Mast Cells by β-Agonists
P Peachell
Clinical Reviews in Allergy & Immunology 2006
Persistent effects induced by IL-13 in the lung
PC Fulkerson, CA Fischetti, LM Hassman, NM Nikolaidis, ME Rothenberg
American journal of respiratory cell and molecular biology 2006
Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling
CG Lee, HR Kang, RJ Homer, G Chupp, JA Elias
Proceedings of the American Thoracic Society 2006
Prostaglandin E2activates EP2receptors to inhibit human lung mast cell degranulation
LJ Kay, WW Yeo, PT Peachell
British Journal of Pharmacology 2006
Structural Changes in Airway Diseases
C Bergeron, LP Boulet
Chest 2006
Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge
A Hirano, A Kanehiro, K Ono, W Ito, A Yoshida, C Okada, H Nakashima, Y Tanimoto, M Kataoka, EW Gelfand, M Tanimoto
American journal of respiratory cell and molecular biology 2006
Effective mucus clearance is essential for respiratory health.
Randell SH, Boucher RC
American journal of respiratory cell and molecular biology 2006
Adenosine signaling in asthma and chronic obstructive pulmonary disease
A Mohsenin, MR Blackburn
Current Opinion in Pulmonary Medicine 2006
Airway Remodeling in Asthma and its Influence on Clinical Pathophysiology
K Yamauchi
The Tohoku Journal of Experimental Medicine 2006
Immunostimulatory DNA inhibits allergen-induced peribronchial angiogenesis in mice
SY Lee, JY Cho, M Miller, K McElwain, S McElwain, P Sriramarao, E Raz, DH Broide
Journal of Allergy and Clinical Immunology 2006
Endothelin-1 Regulates Proliferative Responses, both alone and Synergistically with PDGF, in Rat Tracheal Smooth Muscle Cells
L Yahiaoui, A Villeneuve, H Valderrama-Carvajal, F Burke, ED Fixman
Cellular Physiology and Biochemistry 2006
Gene expression analysis in a murine model of allergic asthma reveals overlapping disease and therapy dependent pathways in the lung
MT Follettie, DK Ellis, DD Donaldson, AA Hill, V Diesl, C DeClercq, JP Sypek, AJ Dorner, M Wills-Karp
The Pharmacogenomics Journal 2006
Mechanisms of Giant Papillary Formation in Vernal Keratoconjunctivitis
N Kato, K Fukagawa, M Dogru, H Fujishima, K Tsubota
Cornea 2006
Effects of TGF-β and glucocorticoids on map kinase phosphorylation, IL-6/IL-11 secretion and cell proliferation in primary cultures of human lung fibroblasts
G Pelaia, L Gallelli, B D'Agostino, A Vatrella, G Cuda, D Fratto, T Renda, U Galderisi, E Piegari, N Crimi, F Rossi, M Caputi, FS Costanzo, C Vancheri, R Maselli, SA Marsico
Journal of Cellular Physiology 2006
ADAM33 haplotypes are associated with asthma in a large Australian population
MA Kedda, DL Duffy, B Bradley, RE O’Hehir, PJ Thompson
European Journal of Human Genetics 2006
α3α5β2-Nicotinic Acetylcholine Receptor Contributes to the Wound Repair of the Respiratory Epithelium by Modulating Intracellular Calcium in Migrating Cells
JM Tournier, K Maouche, C Coraux, JM Zahm, I Cloëz-Tayarani, B Nawrocki-Raby, A Bonnomet, H Burlet, F Lebargy, M Polette, P Birembaut
The American Journal of Pathology 2006
Prolonged ozone exposure in an allergic airway disease model: adaptation of airway responsiveness and airway remodeling
AS Jang, IS Choi, JH Lee, CS Park, CS Park
Respiratory Research 2006
Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels
J Batra, TP Singh, U Mabalirajan, A Sinha, R Prasad, B Ghosh
Thorax 2006
alpha3alpha5beta2-Nicotinic acetylcholine receptor contributes to the wound repair of the respiratory epithelium by modulating intracellular calcium in migrating cells
JM Tournier, K Maouche, C Coraux, JM Zahm, I Cloëz-Tayarani, B Nawrocki-Raby, A Bonnomet, H Burlet, F Lebargy, M Polette, P Birembaut
The American Journal of Pathology 2006
TLR9-Based Immunotherapy for Allergic Disease
T Hayashi, E Raz
The American Journal of Medicine 2006
Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses
S Psarras, E Volonaki, CL Skevaki, M Xatzipsalti, A Bossios, H Pratsinis, S Tsigkos, D Gourgiotis, AG Constantopoulos, A Papapetropoulos, P Saxoni-Papageorgiou, NG Papadopoulos
Journal of Allergy and Clinical Immunology 2006
Tumour necrosis factor-α as a therapeutic target in asthma
JB Morjaria, KS Babu, ST Holgate, R Polosa
Drug Discovery Today: Therapeutic Strategies 2006
Role of RhoA Inactivation in Reduced Cell Proliferation of Human Airway Smooth Muscle by Simvastatin
N Takeda, M Kondo, S Ito, Y Ito, K Shimokata, H Kume
American journal of respiratory cell and molecular biology 2006
Montelukast Treatment Attenuates the Increase in Myofibroblasts Following Low-Dose Allergen Challenge
MM Kelly, J Chakir, D Vethanayagam, LP Boulet, M Laviolette, J Gauldie, PM O'Byrne
Chest 2006
Polymorphism of egfr Intron1 is Associated with Susceptibility and Severity of Asthma
X Wang, J Saito, T Ishida, M Munakata
Journal of Asthma 2006
Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia
J Pierce, J Rir-Sima-Ah, I Estrada, J Wilder, A Strasser, Y Tesfaigzi
American journal of physiology. Lung cellular and molecular physiology 2006
Nucleotides induce IL-6 release from human airway epithelia via P2Y 2 and p38 MAPK-dependent pathways
CD Douillet, WP Robinson, PM Milano, RC Boucher, PB Rich
American journal of physiology. Lung cellular and molecular physiology 2006
Interaction of monocytic cells with respiratory syncytial virus results in activation of NF-κB and PKC-α/β leading to up-regulation of IL-15 gene expression
J Ennaciri, R Ahmad, J Menezes
Journal of leukocyte biology 2006
Disorders of the Respiratory Tract
ML Mintz
2006
Tissue Repair, Contraction and the Myofibroblast
C Chaponnier, A Desmoulière, G Gabbiani
2006
Interactions Between Leukotriene C4 and Interleukin 13 Signaling Pathways in a Mouse Model of Airway Disease
J Chavez, HW Young, DB Corry, MW Lieberman
Archives of pathology & laboratory medicine 2006
Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: implications for the role of respiratory epithelium as a modulator of fibrosis
T Murakawa, MM Kerklo, MR Zamora, Y Wei, RG Gill, PM Henson, FL Grover, MR Nicolls
Journal of immunology (Baltimore, Md. : 1950) 2005
Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation
L Uller, K Rydell-Törmänen, CG Persson, JS Erjefält
Respiratory Research 2005
A novel role of hepatocyte growth factor as an immune regulator through suppressing dendritic cell function
K Okunishi, M Dohi, K Nakagome, R Tanaka, S Mizuno, K Matsumoto, JI Miyazaki, T Nakamura, K Yamamoto
Journal of immunology (Baltimore, Md. : 1950) 2005
Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
B Zhou, MR Comeau, TD Smedt, HD Liggitt, ME Dahl, DB Lewis, D Gyarmati, T Aye, DJ Campbell, SF Ziegler
Nature Immunology 2005
Immune Complex-Dependent Remodeling of the Airway Vasculature in Response to a Chronic Bacterial Infection
AB Aurora, P Baluk, DJ Zhang, SS Sidhu, GM Dolganov, C Basbaum, DM McDonald, N Killeen
Journal of immunology (Baltimore, Md. : 1950) 2005
TRP channels in airway smooth muscle as therapeutic targets
M Gosling, C Poll, S Li
Naunyn-Schmiedeberg's Archives of Pharmacology 2005
Progress in research on relationship between bronchial asthma and Th1/Th2 imbalance
LQ Li
Journal of Chinese Integrative Medicine 2005
Endothelin-1 induces proliferation of human lung fibroblasts and IL-11 secretion through an ETA receptor-dependent activation of map kinases
L Gallelli, G Pelaia, B D'Agostino, G Cuda, A Vatrella, D Fratto, V Gioffrè, U Galderisi, MD Nardo, C Mastruzzo, ET Salinaro, M Maniscalco, M Sofia, N Crimi, F Rossi, M Caputi, FS Costanzo, R Maselli, SA Marsico, C Vancheri
Journal of Cellular Biochemistry 2005
Children with stable asthma have reduced airway matrix metalloproteinase-9 and matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio
GM Doherty, SV Kamath, F Courcey, SN Christie, A Chisakuta, JD Lyons, LG Heaney, M Ennis, MD Shields
Clinical & Experimental Allergy 2005
Increased Levels of CTGF mRNA Expression in a Murine Model of Allergic Airway Inflammation
HM Piao, K Yamauchi, LH Pan, T Nakadate, H Ito, T Mouri, H Kobayashi, T Sawai, T Nakanishi, M Takigawa, H Inoue
Allergology International 2005
Regulatory T cells: which role in the pathogenesis and treatment of allergic disorders?
S Romagnani
Allergy 2005
Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: Effect of hydrofluoroalkane-flunisolide
C Bergeron, HP Hauber, M Gotfried, K Newman, R Dhanda, RJ Servi, MS Ludwig, Q Hamid
Journal of Allergy and Clinical Immunology 2005
Attenuation of bleomycin-induced lung fibrosis in rats by mesna
A El–Medany, HH Hagar, M Moursi, RA Muhammed, FI El-Rakhawy, G El-Medany
European Journal of Pharmacology 2005
Comprehensive Analytical Chemistry
J Malmström
Comprehensive Analytical Chemistry 2005
Interaction of airway epithelial cells (A549) with spores and mycelium of Aspergillus fumigatus
Z Zhang, R Liu, JA Noordhoek, HF Kauffman
Journal of Infection 2005
Nitric oxide paradox in asthma
AC Keller, D Rodriguez, M Russo
Memórias do Instituto Oswaldo Cruz 2005
CCR3 Expression and Function in Asthmatic Airway Smooth Muscle Cells
P Joubert, S Lajoie-Kadoch, I Labonté, AS Gounni, K Maghni, V Wellemans, J Chakir, M Laviolette, Q Hamid, B Lamkhioued
Journal of immunology (Baltimore, Md. : 1950) 2005
Inhibition of Airway Remodeling in IL-5 Deficient Mice
Cho Jae Youn, Marina Miller, Kwang Je Baek, Ji Won Han, Jyothi Nayar, Sook Young Lee, Kirsti McElwain, Shauna McElwain, Stephanie Friedman, David H Broide
Journal of Clinical Investigation 2004
Allergic airway inflammation is exacerbated during acute influenza infection and correlates with increased allergen presentation and recruitment of allergen-specific T-helper type 2 cells
BJ Marsland, CB Scanga, M Kopf, GL Gros
Clinical & Experimental Allergy 2004
Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β 1 –induced Pulmonary Fibrosis
CG Lee, SJ Cho, MJ Kang, SP Chapoval, PJ Lee, PW Noble, T Yehualaeshet, B Lu, RA Flavell, J Milbrandt, RJ Homer, JA Elias
Journal of Experimental Medicine 2004
Reversal of established CD4+ type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodelling
ER Jarman, JR Lamb
Immunology 2004
A critical role for eosinophils in allergic airways remodeling
AA Humbles, CM Lloyd, SJ McMillan, DS Friend, G Xanthou, EE McKenna, S Ghiran, NP Gerard, C Yu, SH Orkin, C Gerard
Science 2004
Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
CG Lee, H Link, P Baluk, RJ Homer, S Chapoval, V Bhandari, MJ Kang, L Cohn, YK Kim, DM McDonald, JA Elias
Nature Medicine 2004
Prolonged allergen challenge in mice leads to persistent airway remodelling.
McMillan SJ, Lloyd CM
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004
Innate Immune Responses in Respiratory Syncytial Virus Infections
S Krishnan, M Halonen, RC Welliver
Viral Immunology 2004
Immunopathogenesis of schistosomiasis
TA Wynn, RW Thompson, AW Cheever, MM Mentink-Kane
Immunological Reviews 2004
Opposing roles for IL-13 and IL-13 receptor alpha2 in health and disease
MM Mentink-Kane, TA Wynn
Immunological Reviews 2004
Leptin: Does it have any role in childhood asthma?
N Guler, E Kirerleri, U Ones, Z Tamay, N Salmayenli, F Darendeliler
Journal of Allergy and Clinical Immunology 2004
Mitogen-activated protein kinases and asthma
G Pelaia, G Cuda, A Vatrella, L Gallelli, M Caraglia, M Marra, A Abbruzzese, M Caputi, R Maselli, FS Costanzo, SA Marsico
Journal of Cellular Physiology 2004
Interleukin-4 receptor signaling pathways in asthma pathogenesis
TA Chatila
Trends in Molecular Medicine 2004
Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling
G Yang, A Volk, T Petley, E Emmell, J Giles-Komar, X Shang, J Li, AM Das, D Shealy, DE Griswold, L Li
Cytokine 2004
Tyrosine kinase inhibitors: a new approach for asthma
WS Wong, KP Leong
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics 2004
The potential use of Chinese herbal medicines in treating allergic asthma
XM Li, TF Zhang, H Sampson, ZM Zou, K Beyer, MC Wen, B Schofield
Annals of Allergy Asthma & Immunology 2004
Prolonged allergen challenge in mice leads to persistent airway remodelling
SJ Mcmillan, CM Lloyd
Clinical & Experimental Allergy 2004
Pro- and Anti-Inflammatory Factors Cooperate to Control Hyaluronan Synthesis in Lung Fibroblasts
TS Wilkinson, S Potter-Perigo, C Tsoi, LC Altman, TN Wight
American journal of respiratory cell and molecular biology 2004
A3 adenosine receptor signaling contributes to airway inflammation and mucus production in adenosine deaminase-deficient mice
HW Young, JG Molina, D Dimina, H Zhong, M Jacobson, LN Chan, TS Chan, JJ Lee, MR Blackburn
Journal of immunology (Baltimore, Md. : 1950) 2004
Immunostimulatory DNA Inhibits Transforming Growth Factor-β Expression and Airway Remodeling
JY Cho, M Miller, KJ Baek, JW Han, J Nayar, M Rodriguez, SY Lee, K McElwain, S McElwain, E Raz, DH Broide
American journal of respiratory cell and molecular biology 2004
Modelling airway remodelling in asthma
CM Lloyd, DS Robinson, SJ McMillan
Drug Discovery Today: Disease Models 2004
Decreased Arginine Bioavailability and Increased Serum Arginase Activity in Asthma
CR Morris, M Poljakovic, L Lavrisha, L Machado, FA Kuypers, SM Morris
American journal of respiratory and critical care medicine 2004
Increased Thrombin Activity after Allergen Challenge: A Potential Link to Airway Remodeling?
M Terada, EA Kelly, NN Jarjour
American journal of respiratory and critical care medicine 2004
Evaluation of cytokine modulators for asthma
L Hendeles, M Asmus, S Chesrown
Paediatric Respiratory Reviews 2004
Plasminogen Activator Inhibitor-1 in the Pathogenesis of Asthma
SH Cho, CH Ryu, CK Oh
Experimental biology and medicine (Maywood, N.J.) 2004
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
M Mall, BR Grubb, JR Harkema, WK O'Neal, RC Boucher
Nature Medicine 2004
Transgenic smooth muscle expression of the human CysLT 1 receptor induces enhanced responsiveness of murine airways to leukotriene D 4
G Yang, A Haczku, H Chen, V Martin, H Galczenski, Y Tomer, CR van Beisen, JF Evans, RA Panettieri, CD Funk
American journal of physiology. Lung cellular and molecular physiology 2004
T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice
R Leigh, DS Southam, R Ellis, JN Wattie, R Sehmi, Y Wan, MD Inman
Journal of applied physiology 2004
Neutrophil elastase induces mucus cell metaplasia in mouse lung
JA Voynow, BM Fischer, DE Malarkey, LH Burch, T Wong, M Longphre, SB Ho, WM Foster
American journal of physiology. Lung cellular and molecular physiology 2004
Immunostimulatory DNA Reverses Established Allergen-Induced Airway Remodeling
CJ Youn, M Miller, KJ Baek, JW Han, J Nayar, SY Lee, K McElwain, S McElwain, E Raz, DH Broide
Journal of immunology (Baltimore, Md. : 1950) 2004
Clinical Assessment of Airway Remodeling in Asthma: Utility of Computed Tomography
A Niimi, H Matsumoto, M Takemura, T Ueda, Y Nakano, M Mishima
Clinical Reviews in Allergy & Immunology 2004
Dissection of experimental asthma with DNA microarray analysis: identification of arginase in asthma pathogenesis
Nives Zimmermann, Nina E. King, Johanne Laporte, Ming Yang, Anil Mishra, Sam M. Pope, Emily E. Muntel, David P. Witte, Anthony A. Pegg, Paul S. Foster, Qutayba Hamid, Marc E. Rothenberg
Journal of Clinical Investigation 2003
ADENOSINE MEDIATES IL-13- INDUCED INFLAMMATION AND REMODELING IN THE LUNG: EVIDENCE FOR AN IL-13-ADENOSINE AMPLIFICATION PATHWAY
Michael R. Blackburn, Chun G. Lee, Hays W. J. Young, Zhou Zhu, Janci L. Chunn, Min Jong Kang, Suman K. Banerjee, Jack A. Elias
Journal of Clinical Investigation 2003
Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma
M Schmidt, G Sun, MA Stacey, L Mori, S Mattoli
Journal of immunology (Baltimore, Md. : 1950) 2003
Regulation of Activin A Expression in Mast Cells and Asthma: Its Effect on the Proliferation of Human Airway Smooth Muscle Cells
SH Cho, Z Yao, SW Wang, RF Alban, RG Barbers, SW French, CK Oh
Journal of immunology (Baltimore, Md. : 1950) 2003
Physiopathology of airway hyperresponsiveness
LP Boulet
Current Allergy and Asthma Reports 2003
Mast cells play a partial role in allergen-induced subepithelial fibrosis in a murine model of allergic asthma
T Masuda, H Tanaka, M Komai, K Nagao, M Ishizaki, D Kajiwara, H Nagai
Clinical & Experimental Allergy 2003
Oncostatin M: an interleukin-6-like cytokine relevant to airway remodelling and the pathogenesis of asthma
KA O'Hara, MA Kedda, PJ Thompson, DA Knight
Clinical & Experimental Allergy 2003
Respiratory syncytial virus augments production of fibroblast growth factor basic in vitro: Implications for a possible mechanism of prolonged wheezing after infection
A Dosanjh, S Rednam, M Martin
Pediatric Allergy and Immunology 2003
Identification of Antigenic Epitopes on Human Allergens: Studies with HLA Transgenic Mice
SP Chapoval, CS David
Environmental Health Perspectives 2003
Inhibition of MMP-9 expression by PPARgamma activators in human bronchial epithelial cells
M Hetzel, D Walcher, M Grüb, H Bach, V Hombach, N Marx
Thorax 2003
Identification of antigenic epitopes on human allergens: studies with HLA transgenic mice
SP Chapoval, CS David
Environmental Health Perspectives 2003
Epithelial-mesenchymal interactions in the pathogenesis of asthma
ST Holgate, DE Davies, S Puddicombe, A Richter, P Lackie, J Lordan, P Howarth
Allergology International 2003
The plasmin system in airway remodeling
I Kucharewicz, K Kowal, W Buczko, A Bodzenta-Łukaszyk
Thrombosis Research 2003
Lung Biology in Health and Disease
N Zamel
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential 2003
Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions
M Toda, DY Leung, S Molet, M Boguniewicz, R Taha, P Christodoulopoulos, T Fukuda, JA Elias, QA Hamid
Journal of Allergy and Clinical Immunology 2003
Chemokines in the Lung
W Tsai, B Mehrad
Chemokines in the Lung 2003
Role of Prostaglandin I2 in Airway Remodeling Induced by Repeated Allergen Challenge in Mice
K Nagao, H Tanaka, M Komai, T Masuda, S Narumiya, H Nagai
American journal of respiratory cell and molecular biology 2003
Transgenic modeling of interleukin-13 in the lung
JA Elias, T Zheng, CG Lee, RJ Homer, Q Chen, B Ma, M Blackburn, Z Zhu
Chest 2003
Correlation of Reticular Basement Membrane Thickness and Airway Wall Remodeling in Asthma
FH CHEN, KT SAMSON, K UENO, Y ODAJIMA, S SHIODA
The Showa University Journal of Medical Sciences 2003
Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling
Stephen T Holgate, Marc Peters-Golden, Reynold A Panettieri, William R Henderson Jr
Journal of Allergy and Clinical Immunology 2003
Airway Remodeling of Murine Chronic Antigen Exposure Model
T Tsuchiya, Y Nishimura, T Nishiuma, Y Kotani, Y Funada, S Yoshimura, M Yokoyama
Journal of Asthma 2003
Histopathology of Severe Childhood Asthma
HA Jenkins, C Cool, SJ Szefler, R Covar, S Brugman, EW Gelfand, JD Spahn
Chest 2003
An in vitro airway wall model of remodeling
MM Choe, PH Sporn, MA Swartz
American journal of physiology. Lung cellular and molecular physiology 2003
Impact of endogenous adenosine on airway hyperreactivity
MR Blackburn, HW Young
Drug Development Research 2003
Le remodelage bronchique dans l’asthme : mécanismes et enjeux thérapeutiques
L Benayoun, M Pretolani
médecine/sciences 2003
IL-4 Induces Apoptosis in A549 Lung Adenocarcinoma Cells: Evidence for the Pivotal Role of 15-Hydroxyeicosatetraenoic Acid Binding to Activated Peroxisome Proliferator-Activated Receptor γ Transcription Factor
P Shankaranarayanan, S Nigam
Journal of immunology (Baltimore, Md. : 1950) 2003
CD8+ T cells and immunoregulatory networks in asthma
BJ Marsland, GL Gros
Springer Seminars in Immunopathology 2003
Measuring Subepithelial Thickness Using Endobronchial Ultrasonography in a Patient with Asthma: A Case Report
A Yamasaki, K Tomita, H Sano, M Watanabe, H Makino, J Kurai, Y Hitsuda, E Shimizu
Lung 2003
Overlapping and enzyme-specific contributions of matrix metalloproteinase (MMP)-9 and MMP-12 to the pathogenesis of IL-13-induced inflammation and alveolar remodeling in the lung
Sophie Lanone, Tao Zheng, Zhou Zhu, Wei Liu, Chun Geun Lee, Bing Ma, Qingsheng Chen, Robert J. Homer, Jingming Wang, Lesley A. Rabach, Morgan E. Rabach, J. Michael Shipley, Steven D. Shapiro, Robert M. Senior, Jack A. Elias
Journal of Clinical Investigation 2002
A Role for Cysteinyl Leukotrienes in Airway Remodeling in a Mouse Asthma Model
WR Henderson, LO Tang, SJ Chu, SM Tsao, GK Chiang, F Jones, M Jonas, C Pae, H Wang, EY Chi
American journal of respiratory and critical care medicine 2002
Bronchial epithelial compression regulates MAP kinase signaling and HB-EGF-like growth factor expression
DJ Tschumperlin, JD Shively, MA Swartz, ES Silverman, KJ Haley, G Raab, JM Drazen
American journal of physiology. Lung cellular and molecular physiology 2002
AT 2 ‐Receptor activation regulates myocardial eNOS expression via the calcineurin‐NF‐AT pathway
O Ritter, K Schuh, M Breden, N Röthlein, N Burkard, L Hein, L Neyses
The FASEB Journal 2002
Induction of MCP-1 expression in airway epithelial cells: role of CCR2 receptor in airway epithelial injury
Matthew C Lundien, Kamal A Mohammed, Najmunnisa Nasreen, R S Tepper, Joyce A Hardwick, Kerry L Sanders, Robert D Van Horn, Veena B Antony
Journal of Clinical Immunology 2002
The role of Th1/Th2 polarization in mucosal immunity
MF Neurath, S Finotto, LH Glimcher
Nature Medicine 2002
Role of cytokines and chemokines in bronchial hyperresponsiveness and airway inflammation
Y Riffo-Vasquez, D Spina
Pharmacology & Therapeutics 2002
Recent Concepts in the Pathogenesis and Treatment of Asthma
LA Whittaker, L Cohn
Clinical Pulmonary Medicine 2002
THEPATHOPHYSIOLOGY OFASTHMA
L Maddox, DA Schwartz
Annual Review of Medicine 2002
Lack of effect of bone marrow transplantation on airway hyperresponsiveness in an asthmatic
K Iizuka, T Sakura, A Yoshii, S Miyawaki, T Oyama, K Dobashi, T Nakazawa, M Mori
Allergology International 2002
Pathophysiology of airway mucosa
H TANAKA, H NAGAI
Folia Pharmacologica Japonica 2002
The involvement of matrix metalloproteinases in basement membrane injury in a murine model of acute allergic airway inflammation
K Kumagai, I Ohno, K Imai, J Nawata, K Hayashi, S Okada, H Senoo, T Hattori, K Shirato
Clinical & Experimental Allergy 2002
Correlation between the bronchial subepithelial layer and whole airway wall thickness in patients with asthma
K Kasahara, K Shiba, T Ozawa, K Okuda, M Adachi
Thorax 2002
Expression of Smad7 in bronchial epithelial cells is inversely correlated to basement membrane thickness and airway hyperresponsiveness in patients with asthma
A Nakao, H Sagara, Y Setoguchi, T Okada, K Okumura, H Ogawa, T Fukuda
Journal of Allergy and Clinical Immunology 2002
Activation of TGF-β/Smad2 signaling is associated with airway remodeling in asthma
H Sagara, T Okada, K Okumura, H Ogawa, C Ra, T Fukuda, A Nakao
Journal of Allergy and Clinical Immunology 2002
Recurrent aerosol antigen exposure induces distinct patterns of experimental allergic asthma in mice
P Jungsuwadee, G Dekan, G Stingl, MM Epstein
Clinical Immunology 2002
IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling
Z Zhu, B Ma, T Zheng, RJ Homer, CG Lee, IF Charo, P Noble, JA Elias
Journal of immunology (Baltimore, Md. : 1950) 2002
Modeling Allergic Asthma in Mice: Pitfalls and Opportunities
RK Kumar, PS Foster
American journal of respiratory cell and molecular biology 2002
Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth Muscle Cells: Modulation by Glucocorticoids and β -Agonists
AJ Ammit, AL Lazaar, C Irani, GM O'Neill, ND Gordon, Y Amrani, RB Penn, RA Panettieri
American journal of respiratory cell and molecular biology 2002
Cysteinyl leukotriene receptors
Y Hui, CD Funk
Biochemical Pharmacology 2002
Exposição de pequenos animais à hiperoxia - um modelo para estudo do papel do músculo liso na hiperreactividade brônquica
T Gamboa, AB Rendas
Revista Portuguesa de Pneumologia 2002
Protection of Mice from Allergen-induced Asthma by Selenite: PREVENTION OF EOSINOPHIL INFILTRATION BY INHIBITION OF NF-κB ACTIVATION
D Jeong, MH Yoo, TS Kim, JH Kim, IY Kim
The Journal of biological chemistry 2002
Role of capacitative Ca 2+ entry in bronchial contraction and remodeling
M Sweeney, SS McDaniel, O Platoshyn, S Zhang, Y Yu, BR Lapp, Y Zhao, PA Thistlethwaite, JX Yuan
Journal of applied physiology 2002
The Hereditary Basis of Allergic Diseases
ST Holgate, JW Holloway
2002
Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet
S Finotto, MF Neurath, JN Glickman, S Qin, HA Lehr, FH Green, K Ackerman, K Haley, PR Galle, SJ Szabo, JM Drazen, GT Sanctis, LH Glimcher
Science 2002
The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma
A Richter, SM Puddicombe, JL Lordan, F Bucchieri, SJ Wilson, R Djukanovic, G Dent, ST Holgate, DE Davies
American journal of respiratory cell and molecular biology 2001
Sphingosine 1‐phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma
AJ Ammit, AT Hastie, LC Edsall, RK Hoffman, Y Amrani, VP Krymskaya, SA Kane, SP Peters, RB Penn, S Spiegel, RA Panettieri
The FASEB Journal 2001
Regulation of peroxisome proliferator-activated receptor gamma expression in human asthmatic airways: relationship with proliferation, apoptosis, and airway remodeling
L Benayoun, S Letuve, A Druilhe, J Boczkowski, MC Dombret, P Mechighel, J Megret, G Leseche, M Aubier, M Pretolani
American journal of respiratory and critical care medicine 2001
Regulation of allergic airways inflammation by cytokines and glucocorticoids
L Cameron, Q Hamid
Current Allergy and Asthma Reports 2001
Understanding airway wall remodeling in asthma: a basis for improvements in therapy?
RK Kumar
Pharmacology & Therapeutics 2001
Interleukin-4 and interleukin-13 induce fibronectin production by human lung fibroblasts
T Machino, S Hashimoto, Y Gon, K Kujime, S Maruoka, T Horie
Allergology International 2001
Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor  1
CG Lee, RJ Homer, Z Zhu, S Lanone, X Wang, V Koteliansky, JM Shipley, P Gotwals, P Noble, Q Chen, R M., JA Elias
Journal of Experimental Medicine 2001
International Workshop on Equine Chronic Airway Disease Michigan State University 16-18 June 2000
NE Robinson, W Chairperson
Equine Veterinary Journal 2001
Autocrine regulation of asthmatic airway inflammation: role of airway smooth muscle
S McKay, HS Sharma
Respiratory Research 2001
New insights into the role of cytokines in asthma
JC Renauld
Journal of clinical pathology 2001
Complex interactions in complex traits: obesity and asthma
KG Tantisira, ST Weiss
Thorax 2001
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1)
CG Lee, RJ Homer, Z Zhu, S Lanone, X Wang, V Koteliansky, JM Shipley, P Gotwals, P Noble, Q Chen, R M, JA Elias
Journal of Experimental Medicine 2001
Neointimal and Tubulointerstitial Infiltration by Recipient Mesenchymal Cells in Chronic Renal-Allograft Rejection
PC Grimm, P Nickerson, J Jeffery, RC Savani, J Gough, RM McKenna, E Stern, DN Rush
New England Journal of Medicine 2001
IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase–dependent pathway
S Hashimoto, Y Gon, I Takeshita, S Maruoka, T Horie
Journal of Allergy and Clinical Immunology 2001
Suppression of asthma-like responses in different mouse strains by oral tolerance
M Russo, MA Nahori, J Lefort, E Gomes, AC Keller, D Rodriguez, OG Ribeiro, S Adriouch, V Gallois, AM de Faria, BB Vargaftig
American journal of respiratory cell and molecular biology 2001
Therapeutic effect of IL-13 immunoneutralization during chronic experimental fungal asthma
K Blease, C Jakubzick, J Westwick, N Lukacs, SL Kunkel, CM Hogaboam
Journal of immunology (Baltimore, Md. : 1950) 2001
Mechanical stimuli to airway remodeling
DJ Tschumperlin, JM Drazen
American journal of respiratory and critical care medicine 2001
Peroxisome Proliferator–Activated Receptor- γ Regulates Airway Epithelial Cell Activation
AC Wang, X Dai, B Luu, DJ Conrad
American journal of respiratory cell and molecular biology 2001
T-helper type 2 cell-directed therapy for asthma
L Cohn, A Ray
Pharmacology & Therapeutics 2001
Airway Remodeling and Serum Total Immunoglobulin E (IgE) Levels in a Murine Model of Asthma
T Akkoç, S Tolunay, I Barlau, M Basaran
Journal of Asthma 2001
Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-γ
M Ahdieh, T Vandenbos, A Youakim
American journal of physiology. Cell physiology 2001
Invited Review: The circle of life: cell cycle regulation in airway smooth muscle
AJ Ammit, RA Panettieri
Journal of applied physiology 2001
Molecular Biology of Acute Lung Injury
HR Wong, TP Shanley
2001
Adenosine-Dependent Airway Inflammation and Hyperresponsiveness in Partially Adenosine Deaminase-Deficient Mice
JL Chunn, HW Young, SK Banerjee, GN Colasurdo, MR Blackburn
Journal of immunology (Baltimore, Md. : 1950) 2001
Ultrastructural examination of bronchial biopsy specimens from children with moderate asthma.
Cokuğraş H, Akçakaya N, Seçkin, Camcioğlu Y, Sarimurat N, Aksoy F
Thorax 2001
Cytokines in airway inflammation
Y Riffo-Vasquez, S Pitchford, D Spina
The International Journal of Biochemistry & Cell Biology 2000
Novel therapeutics for the treatment of asthma
D Chantry
Expert Opinion on Emerging Drugs 2000
Interferon gamma induction of pulmonary emphysema in the adult murine lung
Z Wang, T Zheng, Z Zhu, RJ Homer, RJ Riese, HA Chapman, SD Shapiro, JA Elias
Journal of Experimental Medicine 2000
T-cell subsets (Th1 versus Th2)
S Romagnani
Annals of Allergy Asthma & Immunology 2000
Inflammatory and structural changes in the airways of patients with asthma
ST Holgate
Respiratory Medicine 2000
The role of lymphocytes in allergic disease
S Romagnani
Journal of Allergy and Clinical Immunology 2000
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung
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American journal of physiology. Lung cellular and molecular physiology 2000
Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth-Muscle Cells: Modulation by Cyclic Adenosine Monophosphate
AJ Ammit, RK Hoffman, Y Amrani, AL Lazaar, DW Hay, TJ Torphy, RB Penn, RA Panettieri
American journal of respiratory cell and molecular biology 2000
Chemokines and their role in airway hyper-reactivity
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Respiratory Research 2000
What have transgenic and knockout animals taught us about respiratory disease?
YR Vasquez, D Spina
Respiratory Research 2000
IL-11 Selectively Inhibits Aeroallergen-Induced Pulmonary Eosinophilia and Th2 Cytokine Production
J Wang, RJ Homer, L Hong, L Cohn, CG Lee, S Jung, JA Elias
Journal of immunology (Baltimore, Md. : 1950) 2000
Endogenous and Exogenous IL-6 Inhibit Aeroallergen-Induced Th2 Inflammation
J Wang, RJ Homer, Q Chen, JA Elias
Journal of immunology (Baltimore, Md. : 1950) 2000
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