Soumen Roy, Matthew M. Ryals, Astrid Botty Van den Bruele, Tracy S. Fitzgerald, Lisa L. Cunningham
Title and authors | Publication | Year |
---|---|---|
Inhibition of Gpx4-mediated ferroptosis alleviates cisplatin-induced hearing loss in C57BL/6 mice
Ziyi Liu, Hanbing Zhang, Xiuli Bi, Yachun An, Jun Hu, Na Guo, Fengyue Dong, Guodong Hong, Yu Xiao, Wen Li, Xiaoxu Zhao, Siwei Guo, Xiaohan Zhang, Xiaolong Fu, Renjie Chai |
Molecular Therapy | 2024 |
Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice.
Sailor-Longsworth E, Lutze RD, Ingersoll MA, Kelmann RG, Ly K, Currier D, Chen T, Zuo J, Teitz T |
bioRxiv : the preprint server for biology | 2024 |
FDA-Approved MEK1/2 Inhibitor, Trametinib, Protects Mice from Cisplatin and Noise-Induced Hearing Loss
Lutze RD, Ingersoll MA, Kelmann RG, Teitz T |
2024 | |
Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin- and Noise-Induced Hearing Loss
Lutze RD, Ingersoll MA, Kelmann RG, Teitz T |
Pharmaceuticals | 2024 |
Dabrafenib protects from cisplatin-induced hearing loss in a clinically relevant mouse model
Matthew Ingersoll, Richard Lutze, Chithra Pushpan, Regina Kelmann, Huizhan Liu, Mark May, William Hunter, David He, Tal Teitz |
JCI Insight | 2023 |
Sound conditioning strategy promoting paracellular permeability of the blood‐labyrinth‐barrier benefits inner ear drug delivery
Wang X, Gu J, Xu K, Xu B, Yu D, Wu H |
Bioengineering & Translational Medicine | 2023 |
Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning
Zhao R, Ma C, Wang M, Li X, Liu W, Shi L, Yu N |
Frontiers in synaptic neuroscience | 2022 |
Early Physiological and Cellular Indicators of Cisplatin-Induced Ototoxicity
Y Chen, EC Bielefeld, JG Mellott, W Wang, AM Mafi, EN Yamoah, J Bao |
Journal of the Association for Research in Otolaryngology | 2021 |
Hsp70/Bmi1-FoxO1-SOD Signaling Pathway Contributes to the Protective Effect of Sound Conditioning against Acute Acoustic Trauma in a Rat Model
G Zhu, Y Wu, Y Qiu, K Tian, W Mi, X Liu, Y Chen, J Jia, J Luo, L Lu, J Qiu, R Chai |
Neural plasticity | 2020 |
BRAF inhibition protects against hearing loss in mice
MA Ingersoll, EA Malloy, LE Caster, EM Holland, Z Xu, M Zallocchi, D Currier, H Liu, DZ He, J Min, T Chen, J Zuo, T Teitz |
Science Advances | 2020 |
Cochlear detoxification: Role of alpha class glutathione transferases in protection against oxidative lipid damage, ototoxicity, and cochlear aging
S Someya, MJ Kim |
Hearing Research | 2020 |
Current Strategies to Combat Cisplatin-Induced Ototoxicity
D Yu, J Gu, Y Chen, W Kang, X Wang, H Wu |
Frontiers in pharmacology | 2020 |
Strategies to reduce the risk of platinum containing antineoplastic drug-induced ototoxicity
D Mukherjea, A Dhukhwa, A Sapra, P Bhandari, K Woolford, J Franke, V Ramkumar, L Rybak |
Expert Opinion on Drug Metabolism & Toxicology | 2020 |
Ototoxicity and Platinum Uptake Following Cyclic Administration of Platinum-Based Chemotherapeutic Agents
BK Gersten, TS Fitzgerald, KA Fernandez, LL Cunningham |
Journal of the Association for Research in Otolaryngology | 2020 |
Novel QUEST MRI In Vivo Measurement of Noise-induced Oxidative Stress in the Cochlea
A Kühl, A Dixon, M Hali, AK Apawu, A Muca, M Sinan, J Warila, RD Braun, BA Berkowitz, AG Holt |
Scientific Reports | 2019 |
Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea
P Bhatta, A Dhukhwa, K Sheehan, RF Aameri, V Borse, S Ghosh, S Sheth, C Mamillapalli, L Rybak, V Ramkumar, D Mukherjea |
Scientific Reports | 2019 |
Necroptosis and apoptosis contribute to cisplatin and aminoglycoside ototoxicity
D Ruhl, TT Du, EL Wagner, JH Choi, S Li, R Reed, K Kim, M Freeman, G Hashisaki, JR Lukens, JB Shin |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2019 |
An optimized, clinically relevant mouse model of cisplatin-induced ototoxicity
K Fernandez, T Wafa, TS Fitzgerald, LL Cunningham |
Hearing Research | 2019 |
GSTA4 mediates reduction of cisplatin ototoxicity in female mice
HJ Park, MJ Kim, C Rothenberger, A Kumar, EM Sampson, D Ding, C Han, K White, K Boyd, S Manohar, YH Kim, MS Ticsa, AS Gomez, I Caicedo, U Bose, PJ Linser, T Miyakawa, M Tanokura, TC Foster, R Salvi, S Someya |
Nature Communications | 2019 |
Poly (ADP-Ribose) Polymerase-1 (PARP1) Deficiency and Pharmacological Inhibition by Pirenzepine Protects From Cisplatin-Induced Ototoxicity Without Affecting Antitumor Efficacy
A Tropitzsch, M Müller, F Paquet-Durand, F Mayer, HG Kopp, A Schrattenholz, A Müller, H Löwenheim |
Frontiers in cellular neuroscience | 2019 |
Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies
CJ Kros, PS Steyger |
Cold Spring Harbor Perspectives in Medicine | 2018 |
The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It
H Armstrong, M Bording-Jorgensen, S Dijk, E Wine |
Cancers | 2018 |
CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss
T Teitz, J Fang, AN Goktug, JD Bonga, S Diao, RA Hazlitt, L Iconaru, M Morfouace, D Currier, Y Zhou, RA Umans, MR Taylor, C Cheng, J Min, B Freeman, J Peng, MF Roussel, R Kriwacki, RK Guy, T Chen, J Zuo |
Journal of Experimental Medicine | 2018 |
PD-1 Inhibition Minimally Affects Cisplatin-Induced Toxicities in a Murine Model
K Spielbauer, L Cunningham, N Schmitt |
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 2018 |
Cisplatin is retained in the cochlea indefinitely following chemotherapy
AM Breglio, AE Rusheen, ED Shide, KA Fernandez, KK Spielbauer, KM McLachlin, MD Hall, L Amable, LL Cunningham |
Nature Communications | 2017 |
Aminoglycoside-Induced Cochleotoxicity: A Review
M Jiang, T Karasawa, PS Steyger |
Frontiers in cellular neuroscience | 2017 |
Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection
S Sheth, D Mukherjea, LP Rybak, V Ramkumar |
Frontiers in cellular neuroscience | 2017 |
Potential Mechanisms Underlying Inflammation-Enhanced Aminoglycoside-Induced Cochleotoxicity
M Jiang, F Taghizadeh, PS Steyger |
Frontiers in cellular neuroscience | 2017 |
Magnetic Nanoparticle Mediated Steroid Delivery Mitigates Cisplatin Induced Hearing Loss
B Ramaswamy, S Roy, AB Apolo, B Shapiro, DA Depireux |
Frontiers in cellular neuroscience | 2017 |
Cisplatin Alters Antitumor Immunity and Synergizes with PD-1/PD-L1 Inhibition in Head and Neck Squamous Cell Carcinoma
L Tran, CT Allen, R Xiao, E Moore, R Davis, SJ Park, K Spielbauer, CV Waes, NC Schmitt |
Cancer immunology research | 2017 |
c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea
T Anttonen, A Herranen, J Virkkala, A Kirjavainen, P Elomaa, M Laos, X Liang, J Ylikoski, A Behrens, U Pirvola |
eNeuro | 2016 |
An integrated view of cisplatin-induced nephrotoxicity and ototoxicity
T Karasawa, PS Steyger |
Toxicology Letters | 2015 |
Live imaging the phagocytic activity of inner ear supporting cells in response to hair cell death
EL Monzack, LA May, S Roy, JE Gale, LL Cunningham |
Cell Death and Differentiation | 2015 |
Risk of Sudden Sensorineural Hearing Loss in Patients with Common Preexisting Sensorineural Hearing Impairment: A Population-Based Study in Taiwan
M Koo, JH Hwang, JI Matsui |
PloS one | 2015 |
Endotoxemia-mediated inflammation potentiates aminoglycoside-induced ototoxicity
JW Koo, L Quintanilla-Dieck, M Jiang, J Liu, ZD Urdang, JJ Allensworth, CP Cross, H Li, PS Steyger |
Science Translational Medicine | 2015 |
Antrodia cinnamomea alleviates cisplatin-induced hepatotoxicity and enhances chemo-sensitivity of line-1 lung carcinoma xenografted in BALB/cByJ mice
TH Huang, YH Chiu, YL Chan, H Wang, TL Li, Y Chu, CY Liu, CT Yang, TY Lee, JS You, KH Hsu, CJ Wu |
Oncotarget | 2015 |
Heat Shock Protein-Mediated Protection Against Cisplatin-Induced Hair Cell Death
TG Baker, S Roy, CS Brandon, IK Kramarenko, SP Francis, M Taleb, KM Marshall, R Schwendener, FS Lee, LL Cunningham |
Journal of the Association for Research in Otolaryngology | 2014 |
[Lack of protection against gentamicin ototoxicity by auditory conditioning with noise].
Strose A, Hyppolito MÂ, Colombari GC, Rossato M, Oliveira JA |
Brazilian Journal of Otorhinolaryngology | 2014 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |