Eugene J. Koay, Mark J. Truty, Vittorio Cristini, Ryan M. Thomas, Rong Chen, Deyali Chatterjee, Ya’an Kang, Priya R. Bhosale, Eric P. Tamm, Christopher H. Crane, Milind Javle, Matthew H. Katz, Vijaya N. Gottumukkala, Marc A. Rozner, Haifa Shen, Jeffery E. Lee, Huamin Wang, Yuling Chen, William Plunkett, James L. Abbruzzese, Robert A. Wolff, Gauri R. Varadhachary, Mauro Ferrari, Jason B. Fleming
Title and authors | Publication | Year |
---|---|---|
Cancer and Cardiovascular Disease: The Conjoined Twins
Zmaili M, Alzubi J, Alkhayyat M, Albakri A, Alkhalaileh F, Longinow J, Moudgil R |
Cancers | 2024 |
PanIN or IPMN? Redefining lesion size in three dimensions
Kiemen AL, Dequiedt L, Shen Y, Zhu Y, Matos-Romero V, Forjaz A, Campbell K, Dhana W, Cornish T, Braxton AM, Wu P, Fishman EK, Wood LD, Wirtz D, Hruban RH |
The American Journal of Surgical Pathology | 2024 |
Emerging Challenges to Cellular Therapy of Cancer
Lulla PD, Brenner M |
Cancer journal (Sudbury, Mass.) | 2023 |
Early Diagnosis of Pancreatic Cancer: Clinical Premonitions, Timely Precursor Detection and Increased Curative-Intent Surgery
Søreide K, Ismail W, Roalsø M, Ghotbi J, Zaharia C |
Cancer control : journal of the Moffitt Cancer Center | 2023 |
Use of time‑density curves of dynamic contrast‑enhanced computed tomography for determination of the histological therapeutic effects of neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma
Goto S, Yoshizawa T, Ishido K, Seino H, Morohashi S, Ogasawara H, Kubota S, Ogasawara K, Nakamura A, Hakamada K, Kijima H |
Oncology reports | 2023 |
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+CAFs in intrahepatic cholangiocarcinoma
Li J, Wu X, Ni X, Li Y, Xu L, Hao X, Zhao W, Zhu X, Yin X |
Clinical and Translational Medicine | 2023 |
Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity
McCarthy GA, Di Niro R, Finan JM, Jain A, Guo Y, Wyatt CR, Guimaraes AR, Waugh TA, Keith D, Morgan TK, Sears RC, Brody JR |
2023 | |
A comprehensive review of 3D cancer models for drug screening and translational research
Sharma K, Dey S, Karmakar R, Rengan AK |
2023 | |
PIONEER-Panc: a platform trial for phase II randomized investigations of new and emerging therapies for localized pancreatic cancer
J Douglas, S Liu, J Ma, R Wolff, S Pant, A Maitra, E Tamm, P Bhosale, M Katz, G Varadhachary, E Koay |
BMC Cancer | 2022 |
Baseline CT-based Radiomic Features Aid Prediction of Nodal Positivity after Neoadjuvant Therapy in Pancreatic Cancer
S Elsherif, S Javadi, O Le, N Lamba, M Katz, E Tamm, P Bhosale |
2022 | |
Functional biomarkers derived from computed tomography and magnetic resonance imaging differentiate PDAC subgroups and reveal gemcitabine-induced hypo-vascularization.
Heid I, Trajkovic-Arsic M, Lohöfer F, Kaissis G, Harder FN, Mayer M, Topping GJ, Jungmann F, Crone B, Wildgruber M, Karst U, Liotta L, Algül H, Yen HY, Steiger K, Weichert W, Siveke JT, Makowski MR, Braren RF |
European Journal of Nuclear Medicine and Molecular Imaging | 2022 |
An EGFR/HER2-targeted conjugate sensitizes gemcitabine-sensitive and resistant pancreatic cancer through different SMAD4-mediated mechanisms.
Yao H, Song W, Cao R, Ye C, Zhang L, Chen H, Wang J, Shi Y, Li R, Li Y, Liu X, Zhou X, Shao R, Li L |
Nature Communications | 2022 |
Sustained degradation of hyaluronic acid using an in situ forming implant
Hopkins K, Buno K, Romick N, Freitas dos Santos AC, Tinsley S, Wakelin E, Kennedy J, Ladisch M, Allen-Petersen BL, Solorio L |
2022 | |
Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer
Wang CX, Elganainy D, Zaid MM, Butner JD, Agrawal A, Nizzero S, Minsky BD, Holliday EB, Taniguchi CM, Smith GL, Koong AC, Herman JM, Das P, Maitra A, Wang H, Wolff RA, Katz MH, Crane CH, Cristini V, Koay EJ |
International journal of radiation oncology, biology, physics | 2022 |
Endothelin-axis antagonism enhances tumor perfusion in pancreatic cancer.
Gautam SK, Dalal V, Sajja BR, Gupta S, Gulati M, Dwivedi NV, Aithal A, Cox JL, Rachagani S, Liu Y, Chung V, Salgia R, Batra SK, Jain M |
Cancer Letters | 2022 |
A Mathematical Model to Estimate Chemotherapy Concentration at the Tumor-Site and Predict Therapy Response in Colorectal Cancer Patients with Liver Metastases
DA Anaya, P Dogra, Z Wang, M Haider, J Ehab, DK Jeong, M Ghayouri, GY Lauwers, K Thomas, R Kim, JD Butner, S Nizzero, JR Ramírez, M Plodinec, RL Sidman, WK Cavenee, R Pasqualini, W Arap, JB Fleming, V Cristini |
Cancers | 2021 |
Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling
JD Butner, GV Martin, Z Wang, B Corradetti, M Ferrari, N Esnaola, C Chung, DS Hong, JW Welsh, N Hasegawa, EA Mittendorf, SA Curley, SH Chen, PY Pan, SK Libutti, S Ganesan, RL Sidman, R Pasqualini, W Arap, EJ Koay, V Cristini |
eLife | 2021 |
Stellate Cells Aid Growth-Permissive Metabolic Reprogramming and Promote Gemcitabine Chemoresistance in Pancreatic Cancer
M Amrutkar, IP Gladhaug |
Cancers | 2021 |
Drug Repurposing, an Attractive Strategy in Pancreatic Cancer Treatment: Preclinical and Clinical Updates
LD Lellis, S Veschi, N Tinari, Z Mokini, S Carradori, D Brocco, R Florio, A Grassadonia, A Cama |
Cancers | 2021 |
A mathematical model for the quantification of a patient’s sensitivity to checkpoint inhibitors and long-term tumour burden
JD Butner, Z Wang, D Elganainy, KA Feghali, M Plodinec, GA Calin, P Dogra, S Nizzero, J Ruiz-Ramírez, GV Martin, HA Tawbi, C Chung, EJ Koay, JW Welsh, DS Hong, V Cristini |
Nature Biomedical Engineering | 2021 |
Prediction of Tumor Cellularity in Resectable PDAC from Preoperative Computed Tomography Imaging
F Jungmann, GA Kaissis, S Ziegelmayer, F Harder, C Schilling, HY Yen, K Steiger, W Weichert, R Schirren, IE Demir, H Friess, MR Makowski, RF Braren, FK Lohöfer |
Cancers | 2021 |
ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer
A Gorur, R Bayraktar, C Ivan, HA Mokhlis, E Bayraktar, N Kahraman, D Karakas, S Karamil, NN Kabil, P Kanlikilicer, B Aslan, L Tamer, Z Wang, V Cristini, G Lopez-Berestein, G Calin, B Ozpolat |
Molecular Therapy — Nucleic Acids | 2021 |
Clinicopathological correlation of radiologic measurement of post-therapy tumor size and tumor volume for pancreatic ductal adenocarcinoma
D Wei, MM Zaid, MH Katz, LR Prakash, M Kim, CW Tzeng, JE Lee, A Agrawal, A Rashid, H Wang, G Varadhachary, RA Wolff, EP Tamm, PR Bhosale, A Maitra, EJ Koay, H Wang |
Pancreatology | 2021 |
A novel gene signature for prognosis prediction and chemotherapy response in patients with pancreatic cancer
H Lin, C Hu, S Zheng, X Zhang, R Chen, Q Zhou |
Aging | 2021 |
Ferroptosis: At the Crossroad of Gemcitabine Resistance and Tumorigenesis in Pancreatic Cancer
J Yang, J Xu, B Zhang, Z Tan, Q Meng, J Hua, J Liu, W Wang, S Shi, X Yu, C Liang |
International journal of molecular sciences | 2021 |
Digital twinning of Cellular Capsule Technology: Emerging outcomes from the perspective of porous media mechanics
S Urcun, PY Rohan, W Skalli, P Nassoy, SP Bordas, G Sciumè, K Garikipati |
PloS one | 2021 |
Seed- and Soil-Dependent Differences in Murine Breast Tumor Microenvironments Dictate Anti-PD-L1 IgG Delivery and Therapeutic Efficacy
YT Liu, S Goel, M Kai, JA Guerrero, T Nguyen, J Mai, H Shen, A Ziemys, K Yokoi |
Pharmaceutics | 2021 |
Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming
T Li, H Tong, H Yin, Y Luo, J Zhu, Z Qin, S Yin, W He |
Cancer Cell International | 2021 |
Pre-operative radiomics model for prognostication in resectable pancreatic adenocarcinoma with external validation
GM Healy, E Salinas-Miranda, R Jain, X Dong, D Deniffel, A Borgida, A Hosni, DT Ryan, N Njeze, A McGuire, KC Conlon, JD Dodd, ER Ryan, RC Grant, S Gallinger, MA Haider |
European Radiology | 2021 |
Radiomic analysis identifies tumor subtypes associated with distinct molecular and microenvironmental factors in head and neck squamous cell carcinoma
E Katsoulakis, Y Yu, AP Apte, JE Leeman, N Katabi, L Morris, JO Deasy, TA Chan, NY Lee, N Riaz, V Hatzoglou, JH Oh |
Oral Oncology | 2020 |
ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells
M Liu, Y Zhang, J Yang, X Cui, Z Zhou, H Zhan, K Ding, X Tian, Z Yang, KM Fung, BH Edil, RG Postier, MS Bronze, ME Fernandez-Zapico, MP Stemmler, T Brabletz, YP Li, CW Houchen, M Li |
Gastroenterology | 2020 |
Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment
JS de Maar, AM Sofias, TP Siegel, RJ Vreeken, C Moonen, C Bos, R Deckers |
Theranostics | 2020 |
Mathematical Modeling to Address Challenges in Pancreatic Cancer
P Dogra, JR Ramírez, MJ Peláez, Z Wang, V Cristini, G Parasher, M Rawat |
Current topics in medicinal chemistry | 2020 |
Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy
JD Butner, D Elganainy, CX Wang, Z Wang, SH Chen, NF Esnaola, R Pasqualini, W Arap, DS Hong, J Welsh, EJ Koay, V Cristini |
Science Advances | 2020 |
Predictive Modeling for Voxel-Based Quantification of Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma (PDAC): A Multi-Institutional Study
M Zaid, L Widmann, A Dai, K Sun, J Zhang, J Zhao, MW Hurd, GR Varadhachary, RA Wolff, A Maitra, MH Katz, JM Herman, H Wang, MV Knopp, TM Williams, P Bhosale, EP Tamm, EJ Koay |
Cancers | 2020 |
Early detection of pancreatic cancer
SP Pereira, L Oldfield, A Ney, PA Hart, MG Keane, SJ Pandol, D Li, W Greenhalf, CY Jeon, EJ Koay, CV Almario, C Halloran, AM Lennon, E Costello |
The Lancet Gastroenterology & Hepatology | 2020 |
Upregulation of DUSP14 Affects Proliferation, Invasion and Metastasis, Potentially via Epithelial–Mesenchymal Transition and Is Associated with Poor Prognosis in Pancreatic Cancer Y Wei, G Wang, C Wang, Y Zhou, J Zhang, K Xu |
Cancer management and research | 2020 |
Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine
S Forciniti, ED Pozza, MR Greco, TM Carvalho, B Rolando, G Ambrosini, CA Carmona-Carmona, R Pacchiana, DD Molfetta, M Donadelli, S Arpicco, M Palmieri, SJ Reshkin, I Dando, RA Cardone |
International journal of molecular sciences | 2020 |
Pressure-Enabled Drug Delivery Approach in the Pancreas with Retrograde Venous Infusion of Lipiodol with Ex Vivo Analysis
A Arepally, J Chomas, SC Katz, D Jaroch, KP Kolli, E Prince, RP Liddell |
Cardiovascular and Interventional Radiology | 2020 |
Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells
T Bjånes, S Kotopoulis, ET Murvold, T Kamčeva, BT Gjertsen, OH Gilja, J Schjøtt, B Riedel, E McCormack |
Pharmaceutics | 2020 |
Imaging-Based Subtypes of Pancreatic Ductal Adenocarcinoma Exhibit Differential Growth and Metabolic Patterns in the Pre-Diagnostic Period: Implications for Early Detection
M Zaid, D Elganainy, P Dogra, A Dai, L Widmann, P Fernandes, Z Wang, MJ Pelaez, JR Ramirez, AD Singhi, AK Dasyam, RE Brand, WG Park, S Rahmanuddin, MH Rosenthal, BM Wolpin, N Khalaf, A Goel, DD Hoff, EP Tamm, A Maitra, V Cristini, EJ Koay |
Frontiers in Oncology | 2020 |
Cytotoxic effects of gemcitabine-loaded solid lipid nanoparticles in pancreatic cancer cells
KO Affram, T Smith, E Ofori, S Krishnan, P Underwood, JG Trevino, E Agyare |
Journal of drug delivery science and technology | 2020 |
Diffusion-weighted MRI predicts the histologic response for neoadjuvant therapy in patients with pancreatic cancer: a prospective study (DIFFERENT trial)
K Okada, M Kawai, S Hirono, F Kojima, K Tanioka, M Terada, M Miyazawa, Y Kitahata, Y Iwahashi, M Ueno, S Hayami, S Murata, T Shimokawa, H Yamaue |
Langenbeck's Archives of Surgery | 2020 |
Pancreatic Ductal Adenocarcinoma: Interface Enhancement Gradient Measured on Dual-Energy CT Images Improves Prognostic Evaluation
AM Amer, Y Li, D Summerlin, CM Burgan, MM McNamara, AD Smith, DE Morgan |
2020 | |
Predicting breast cancer response to neoadjuvant chemotherapy based on tumor vascular features in needle biopsies
Terisse A Brocato, Ursa Brown-Glaberman, Zhihui Wang, Reed Selwyn, Colin Wilson, Edward F Wyckoff, Lesley Lomo, Jennifer Saline, Anupama Hooda-Nehra, Renata Pasqualini, Wadih Arap, Jeffrey Brinker, Vittorio Cristini |
JCI Insight | 2019 |
Oridonin overcomes the gemcitabine resistant PANC-1/Gem cells by regulating GST pi and LRP/1 ERK/JNK signalling B Wang, C Shen, Y Li, T Zhang, H Huang, J Ren, Z Hu, J Xu, B Xu |
OncoTargets and therapy | 2019 |
Dynamic Targeting in Cancer Treatment
Z Wang, TS Deisboeck |
Frontiers in physiology | 2019 |
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, G Thurston, Y Zhang, J Lazarus, P Sajjakulnukit, HS Hong, DM Kremer, BS Nelson, S Kemp, L Zhang, D Chang, A Biankin, J Shi, TL Frankel, HC Crawford, JP Morton, MP di Magliano, CA Lyssiotis |
Cell Metabolism | 2019 |
Mathematical modeling in cancer nanomedicine: a review
P Dogra, JD Butner, Y Chuang, S Caserta, S Goel, CJ Brinker, V Cristini, Z Wang |
Biomedical Microdevices | 2019 |
Early Detection of Pancreatic Cancer: Opportunities and Challenges
AD Singhi, EJ Koay, ST Chari, A Maitra |
Gastroenterology | 2019 |
Computed Tomography–Based Biomarker Outcomes in a Prospective Trial of Preoperative FOLFIRINOX and Chemoradiation for Borderline Resectable Pancreatic Cancer
EJ Koay, MH Katz, H Wang, X Wang, L Prakash, M Javle, R Shroff, D Fogelman, S Avila, M Zaid, D Elganainy, Y Lee, CH Crane, S Krishnan, P Das, JB Fleming, JE Lee, EP Tamm, P Bhosale, JH Lee, B Weston, A Maitra, RA Wolff, GR Varadhachary |
JCO Precision Oncology | 2019 |
Enhancement pattern mapping technique for improving contrast‐to‐noise ratios and detectability of hepatobiliary tumors on multiphase computed tomography
PC Park, GW Choi, MM Zaid, D Elganainy, DA Smani, J Tomich, R Samaniego, J Ma, EP Tamm, S Beddar, EJ Koay |
Medical Physics | 2019 |
Tumor Site-Dependent Transport Properties Determine Nanotherapeutics Delivery and Its Efficacy
M Kai, A Ziemys, Y ting Liu, M Kojic, M Ferrari, K Yokoi |
Translational oncology | 2019 |
Pancreatic cancer detection and characterization—state of the art cross-sectional imaging and imaging data analysis
G Kaissis, R Braren |
Translational Gastroenterology and Hepatology | 2019 |
The impact of cancer-associated fibroblasts on major hallmarks of pancreatic cancer
Q Sun, B Zhang, Q Hu, Y Qin, W Xu, W Liu, X Yu, J Xu |
Theranostics | 2018 |
A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma
EJ Koay, Y Lee, V Cristini, JS Lowengrub, Y Kang, FA Lucas, BP Hobbs, R Ye, D Elganainy, M Almahariq, AM Amer, D Chatterjee, H Yan, PC Park, MV Perez, D Li, N Garg, KA Reiss, S Yu, A Chauhan, M Zaid, N Nikzad, RA Wolff, M Javle, GR Varadhachary, RT Shroff, P Das, JE Lee, M Ferrari, A Maitra, CM Taniguchi, MP Kim, CH Crane, MH Katz, H Wang, P Bhosale, EP Tamm, JB Fleming |
Clinical cancer research | 2018 |
Understanding the Connection between Nanoparticle Uptake and Cancer Treatment Efficacy using Mathematical Modeling
TA Brocato, EN Coker, PN Durfee, YS Lin, J Townson, EF Wyckoff, V Cristini, CJ Brinker, Z Wang |
Scientific Reports | 2018 |
Influence of body mass index on the therapeutic efficacy of gemcitabine plus cisplatin and overall survival in lung squamous cell carcinoma: BMI affect the GP chemotherapy in SCC
J Zhong, Q Zheng, E Gao, Z Dong, J Zhao, T An, M Wu, M Zhuo, Y Wang, J Li, S Wang, X Yang, H Chen, B Jia, J Wang, Z Wang |
Thoracic Cancer | 2018 |
Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer
C Tang, B Hobbs, A Amer, X Li, C Behrens, JR Canales, EP Cuentas, P Villalobos, D Fried, JY Chang, DS Hong, JW Welsh, B Sepesi, L Court, II Wistuba, EJ Koay |
Scientific Reports | 2018 |
Imaging-based biomarkers: Changes in the tumor interface of pancreatic ductal adenocarcinoma on computed tomography scans indicate response to cytotoxic therapy: Tumor Interface: Novel Imaging Biomarker
AM Amer, M Zaid, B Chaudhury, D Elganainy, Y Lee, CT Wilke, J Cloyd, H Wang, A Maitra, RA Wolff, G Varadhachary, MJ Overman, JE Lee, JB Fleming, CW Tzeng, MH Katz, EB Holliday, S Krishnan, BD Minsky, JM Herman, CM Taniguchi, P Das, CH Crane, O Le, P Bhosale, EP Tamm, EJ Koay |
Cancer | 2018 |
The BET inhibitor I-BET762 inhibits pancreatic ductal adenocarcinoma cell proliferation and enhances the therapeutic effect of gemcitabine
F Xie, M Huang, X Lin, C Liu, Z Liu, F Meng, C Wang, Q Huang |
Scientific Reports | 2018 |
Mass release curves as the constitutive curves for modeling diffusive transport within biological tissue
M Kojic, M Milosevic, N Kojic, EJ Koay, JB Fleming, M Ferrari, A Ziemys |
Computers in Biology and Medicine | 2018 |
Rab14 overexpression regulates gemcitabine sensitivity through regulation of Bcl-2 and mitochondrial function in pancreatic cancer
J Ge, C Ge |
Virchows Archiv | 2018 |
Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma
X Li, Y Lee, Y Kang, B Dai, MR Perez, M Pratt, EJ Koay, M Kim, RA Brekken, JB Fleming |
Cell Death and Differentiation | 2018 |
Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics
P Dogra, NL Adolphi, Z Wang, YS Lin, KS Butler, PN Durfee, JG Croissant, A Noureddine, EN Coker, EL Bearer, V Cristini, CJ Brinker |
Nature Communications | 2018 |
Chemoresistance Transmission via Exosome-Mediated EphA2 Transfer in Pancreatic Cancer
J Fan, Q Wei, EJ Koay, Y Liu, B Ning, PW Bernard, N Zhang, H Han, MH Katz, Z Zhao, Y Hu |
Theranostics | 2018 |
Correction function for accuracy improvement of the Composite Smeared Finite Element for diffusive transport in biological tissue systems
M Milosevic, V Simic, B Milicevic, EJ Koay, M Ferrari, A Ziemys, M Kojic |
Computer Methods in Applied Mechanics and Engineering | 2018 |
Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe?
Y Huang, D Lin, CM Taniguchi |
Science China Life Sciences | 2017 |
Transport of drugs from blood vessels to tumour tissue
MW Dewhirst, TW Secomb |
Nature Reviews Cancer | 2017 |
Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going
C Liang, S Shi, Q Meng, D Liang, S Ji, B Zhang, Y Qin, J Xu, Q Ni, X Yu |
Experimental & molecular medicine | 2017 |
Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
E Hessmann, MS Patzak, L Klein, N Chen, V Kari, I Ramu, TE Bapiro, KK Frese, A Gopinathan, FM Richards, DI Jodrell, C Verbeke, X Li, R Heuchel, JM Löhr, SA Johnsen, TM Gress, V Ellenrieder, A Neesse |
Gut | 2017 |
Editorial Special Section on Multiscale Cancer Modeling
Z Wang, PK Maini |
IEEE transactions on bio-medical engineering | 2017 |
Dose escalation with an IMRT technique in 15 to 28 fractions is better tolerated than standard doses of 3DCRT for LAPC
LE Colbert, S Moningi, A Chadha, A Amer, Y Lee, RA Wolff, G Varadhachary, J Fleming, M Katz, P Das, S Krishnan, EJ Koay, P Park, CH Crane, CM Taniguchi |
Advances in Radiation Oncology | 2017 |
Novel Diagnostic and Predictive Biomarkers in Pancreatic Adenocarcinoma
JC Chang, M Kundranda |
International journal of molecular sciences | 2017 |
Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine
JM Grixti, S O'Hagan, PJ Day, DB Kell |
Frontiers in pharmacology | 2017 |
Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas
MH Katz, FS Ou, JM Herman, SA Ahmad, B Wolpin, R Marsh, S Behr, Q Shi, M Chuong, LH Schwartz, W Frankel, E Collisson, EJ Koay, JL Hubbard, JL Leenstra, J Meyerhardt, E OReilly |
BMC Cancer | 2017 |
Autocrine DUSP28 signaling mediates pancreatic cancer malignancy via regulation of PDGF-A
J Lee, J Lee, JH Yun, C Choi, S Cho, SJ Kim, JH Kim |
Scientific Reports | 2017 |
Do anti-stroma therapies improve extrinsic resistance to increase the efficacy of gemcitabine in pancreatic cancer?
C Liang, S Shi, Q Meng, D Liang, S Ji, B Zhang, Y Qin, J Xu, Q Ni, X Yu |
Cellular and Molecular Life Sciences | 2017 |
Matrix-regulated integrin α v β 5 maintains α 5 β 1 -dependent desmoplastic traits prognostic of neoplastic recurrence
J Franco-Barraza, R Francescone, T Luong, N Shah, R Madhani, G Cukierman, E Dulaimi, K Devarajan, BL Egleston, E Nicolas, RK Alpaugh, R Malik, RG Uzzo, JP Hoffman, EA Golemis, E Cukierman |
eLife | 2017 |
Detecting circulating tumor material and digital pathology imaging during pancreatic cancer progression
R Moravec, R Divi, M Verma |
World journal of gastrointestinal oncology | 2017 |
Neovascular Prostate-Specific Membrane Antigen Expression Is Associated with Improved Overall Survival under Palliative Chemotherapy in Patients with Pancreatic Ductal Adenocarcinoma
K Stock, K Steinestel, R Wiesch, JH Mikesch, A Hansmeier, M Trautmann, N Beller, J Rehkämper, E Wardelmann, B Heitkötter, W Hartmann, J Sperveslage, S Huss |
BioMed Research International | 2017 |
Pancreatic Cancer Chemoresistance to Gemcitabine
M Amrutkar, I Gladhaug |
Cancers | 2017 |
Preliminary study of tumor heterogeneity in imaging predicts two year survival in pancreatic cancer patients
J Chakraborty, L Langdon-Embry, KM Cunanan, JG Escalon, PJ Allen, MA Lowery, EM OReilly, M Gönen, RG Do, AL Simpson, SK Batra |
PloS one | 2017 |
Safety Study of Targeted and Localized Intra-Arterial Delivery of Gemcitabine in Patients with Locally Advanced Pancreatic Adenocarcinoma
AS Rosemurgy, SB Ross, PL Vitulli, R Malek, J Li, R Agah |
Journal of Pancreatic Cancer | 2017 |
Fibrosis-related miRNAs as serum biomarkers for pancreatic ductal adenocarcinoma
R Suzuki, H Asama, Y Waragai, T Takagi, T Hikichi, M Sugimoto, N Konno, K Watanabe, J Nakamura, H Kikuchi, Y Sato, S Marubashi, A Masamune, H Ohira |
Oncotarget | 2017 |
Establishment of a human primary pancreatic cancer mouse model to examine and investigate gemcitabine resistance
YJ Zhang, CL Wen, YX Qin, XM Tang, MM Shi, BY Shen, Y Fang |
Oncology reports | 2017 |
EUS-guided fine-needle injection of gemcitabine for locally advanced and metastatic pancreatic cancer
MJ Levy, SR Alberts, WR Bamlet, PA Burch, MB Farnell, FC Gleeson, MG Haddock, ML Kendrick, AL Oberg, GM Petersen, N Takahashi, ST Chari |
Gastrointestinal Endoscopy | 2017 |
Matrix control of pancreatic cancer: New insights into fibronectin signaling
M Topalovski, RA Brekken |
Cancer Letters | 2016 |
Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer
PP Adiseshaiah, RM Crist, SS Hook, SE McNeil |
Nature Reviews Clinical Oncology | 2016 |
Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release
H Hosoya, AS Dobroff, WH Driessen, V Cristini, LM Brinker, FI Staquicini, M Cardó-Vila, S DAngelo, F Ferrara, B Proneth, YS Lin, DR Dunphy, P Dogra, MP Melancon, RJ Stafford, K Miyazono, JG Gelovani, K Kataoka, CJ Brinker, RL Sidman, W Arap, R Pasqualini |
Proceedings of the National Academy of Sciences | 2016 |
Conformity analysis to demonstrate reproducibility of target volumes for Margin-Intense Stereotactic Radiotherapy for borderline-resectable pancreatic cancer
DL Holyoake, M Robinson, D Grose, D McIntosh, D Sebag-Montefiore, G Radhakrishna, N Patel, M Partridge, S Mukherjee, MA Hawkins |
Radiotherapy and Oncology | 2016 |
Isolation of Pancreatic Cancer Cells from a Patient-Derived Xenograft Model Allows for Practical Expansion and Preserved Heterogeneity in Culture
K Pham, D Delitto, AE Knowlton, ER Hartlage, R Madhavan, DH Gonzalo, RM Thomas, KE Behrns, TJ George, SJ Hughes, SM Wallet, C Liu, JG Trevino |
The American Journal of Pathology | 2016 |
Theory and Experimental Validation of a Spatio-temporal Model of Chemotherapy Transport to Enhance Tumor Cell Kill
Z Wang, R Kerketta, YL Chuang, P Dogra, JD Butner, TA Brocato, A Day, R Xu, H Shen, E Simbawa, AS AL-Fhaid, SR Mahmoud, SA Curley, M Ferrari, EJ Koay, V Cristini, DD Bernardo |
PLoS computational biology | 2016 |
Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases
T Tanei, F Leonard, X Liu, JF Alexander, Y Saito, M Ferrari, B Godin, K Yokoi |
Cancer research | 2016 |
STAT3 Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
NS Nagathihalli, JA Castellanos, C Shi, Y Beesetty, ML Reyzer, R Caprioli, X Chen, AJ Walsh, MC Skala, HL Moses, NB Merchant |
Gastroenterology | 2015 |
Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression
J Lee, S Condello, B Yakubov, R Emerson, A Caperell-Grant, K Hitomi, J Xie, D Matei |
Clinical cancer research | 2015 |
Nicotine Reduces Survival via Augmentation of Paracrine HGF-MET Signaling in the Pancreatic Cancer Microenvironment
D Delitto, D Zhang, S Han, BS Black, AE Knowlton, AC Vlada, GA Sarosi, KE Behrns, RM Thomas, X Lu, C Liu, TJ George, SJ Hughes, SM Wallet, JG Trevino |
Clinical cancer research | 2015 |
Pancreatic cancer and FOLFIRINOX: a new era and new questions
RD Marsh, MS Talamonti, MH Katz, JM Herman |
Cancer Medicine | 2015 |
Integrated PK-PD and agent-based modeling in oncology
Z Wang, JD Butner, V Cristini, TS Deisboeck |
Journal of Pharmacokinetics and Pharmacodynamics | 2015 |
Blockade of dual-specificity phosphatase 28 decreases chemo-resistance and migration in human pancreatic cancer cells
J Lee, JH Yun, J Lee, C Choi, JH Kim |
Scientific Reports | 2015 |
Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3β-Snail pathway
T Namba, R Kodama, S Moritomo, T Hoshino, T Mizushima |
Cell Death and Disease | 2015 |
Predictive Modeling of Drug Response in Non-Hodgkin’s Lymphoma
HB Frieboes, BR Smith, Z Wang, M Kotsuma, K Ito, A Day, B Cahill, C Flinders, SM Mumenthaler, P Mallick, E Simbawa, AS AL-Fhaid, SR Mahmoud, SS Gambhir, V Cristini, C Cinti |
PloS one | 2015 |
The inflammatory milieu within the pancreatic cancer microenvironment correlates with clinicopathologic parameters, chemoresistance and survival
D Delitto, BS Black, HL Sorenson, AE Knowlton, RM Thomas, GA Sarosi, LL Moldawer, KE Behrns, C Liu, TJ George, JG Trevino, SM Wallet, SJ Hughes |
BMC Cancer | 2015 |
MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma
SA Dhayat, WA Mardin, J Seggewiß, AJ Ströse, C Matuszcak, R Hummel, N Senninger, ST Mees, J Haier, M Fernandez-Zapico |
PloS one | 2015 |
Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models
M DAronzo, M Vinciguerra, T Mazza, C Panebianco, C Saracino, SP Pereira, P Graziano, V Pazienza |
Oncotarget | 2015 |
Quantitative imaging to evaluate malignant potential of IPMNs
AN Hanania, LE Bantis, Z Feng, H Wang, EP Tamm, MH Katz, A Maitra, EJ Koay |
Oncotarget | 2015 |
Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer
EJ Koay, FE Baio, A Ondari, MJ Truty, V Cristini, RM Thomas, R Chen, D Chatterjee, Y Kang, J Zhang, L Court, PR Bhosale, EP Tamm, A Qayyum, CH Crane, M Javle, MH Katz, VN Gottumukkala, MA Rozner, H Shen, JE Lee, H Wang, Y Chen, W Plunkett, JL Abbruzzese, RA Wolff, A Maitra, M Ferrari, GR Varadhachary, JB Fleming |
Physical Biology | 2014 |
Development of a sampling-based global sensitivity analysis workflow for multiscale computational cancer models
Z Wang, V Cristini, TS Deisboeck |
IET Systems Biology | 2014 |
Development of a Diffusion-Based Mathematical Model for Predicting Chemotherapy Effects
Wang Z, Kerketta R, Chuang YL, Cristini V |
2014 | |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |