Our associated microbial communities play a critical role in human health and predisposition to disease, but the degree to which they also shape therapeutic interventions is not well understood. Here, we integrate results from classic and current studies of the direct and indirect impacts of the gut microbiome on the metabolism of therapeutic drugs and diet-derived bioactive compounds. We pay particular attention to microbial influences on host responses to xenobiotics, adding to the growing consensus that treatment outcomes reflect our intimate partnership with the microbial world, and providing an initial framework from which to consider a more comprehensive view of pharmacology and nutrition.
Rachel N. Carmody, Peter J. Turnbaugh
Title and authors | Publication | Year |
---|---|---|
GutBugDB: a web resource to predict the human gut microbiome-mediated biotransformation of biotic and xenobiotic molecules
Longwani U, Sharma AK, Malwe AS, Jaiswal SK, Sharma VK |
Gut Microbiome | 2025 |
The Urogenital System Microbiota: Is It a New Gamechanger in Urogenital Cancers?
Ece G, Aktaş A, Caner A, Sağlık İ, Kula Atik T, Ulusan Bağcı Ö, Bayındır Bilman F, Demirbakan H, Güdül Havuz S, Kaya E, Koyuncu Özyurt Ö, Yetkin G, Zorbozan O |
Microorganisms | 2025 |
Mutualism breakdown underpins evolutionary rescue in an obligate cross-feeding bacterial consortium
Melero-Jiménez IJ, Sorokin Y, Merlin A, Li J, Couce A, Friedman J |
Nature Communications | 2025 |
Mechanisms and Clinical Implications of Human Gut Microbiota-Drug Interactions in the Precision Medicine Era
Wang S, Ju D, Zeng X |
Biomedicines | 2024 |
Current Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes
Przewłócka K, Korewo-Labelle D, Berezka P, Karnia MJ, Kaczor JJ |
Nutrients | 2024 |
Emerging issues in probiotic safety: 2023 perspectives
Merenstein D, Pot B, Leyer G, Ouwehand AC, Preidis GA, Elkins CA, Hill C, Lewis ZT, Shane AL, Zmora N, Petrova MI, Collado MC, Morelli L, Montoya GA, Szajewska H, Tancredi DJ, Sanders ME |
Gut microbes | 2023 |
Neuro-Nutraceutical Polyphenols: How Far Are We?
Gentile MT, Camerino I, Ciarmiello L, Woodrow P, Muscariello L, De Chiara I, Pacifico S |
2023 | |
Forging the microbiome to help us live long and prosper.
Rock RR, Turnbaugh PJ |
PLoS Biology | 2023 |
Dietary Polyphenols, Microbiome, and Multiple Sclerosis: From Molecular Anti-Inflammatory and Neuroprotective Mechanisms to Clinical Evidence.
La Rosa G, Lonardo MS, Cacciapuoti N, Muscariello E, Guida B, Faraonio R, Santillo M, Damiano S |
International journal of molecular sciences | 2023 |
Exploring Gut Microbiome Variations between Popillia japonica Populations of Azores
Frias J, Garriga A, Peñalver Á, Teixeira M, Beltrí R, Toubarro D, Simões N |
Microorganisms | 2023 |
Gut microbial metabolites of dietary polyphenols and their potential role in human health and diseases.
Gade A, Kumar MS |
Journal of Physiology and Biochemistry | 2023 |
Application of artificial intelligence approaches to predict the metabolism of xenobiotic molecules by human gut microbiome
Malwe AS, Sharma VK |
Frontiers in microbiology | 2023 |
Understanding the gut microbiota by considering human evolution: a story of fire, cereals, cooking, molecular ingenuity, and functional cooperation
Tannock GW |
Microbiology and molecular biology reviews : MMBR | 2023 |
Considerations and challenges for sex-aware drug repurposing
Fisher JL, Jones EF, Flanary VL, Williams AS, Ramsey EJ, Lasseigne BN |
Biology of sex differences | 2022 |
Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia
ElMokh O, Matsumoto S, Biniecka P, Bellotti A, Schaeuble K, Piacente F, Gallart-Ayala H, Ivanisevic J, Stamenkovic I, Nencioni A, Nahimana A, Duchosal MA |
Cell Death and Disease | 2022 |
Probiotics, Prebiotics, and Phytogenic Substances for Optimizing Gut Health in Poultry.
Shehata AA, Yalçın S, Latorre JD, Basiouni S, Attia YA, Abd El-Wahab A, Visscher C, El-Seedi HR, Huber C, Hafez HM, Eisenreich W, Tellez-Isaias G |
Microorganisms | 2022 |
Composition and Functional Potential of the Human Mammary Microbiota Prior to and Following Breast Tumor Diagnosis.
Hoskinson C, Zheng K, Gabel J, Kump A, German R, Podicheti R, Marino N, Stiemsma LT |
mSystems | 2022 |
Phytonutrients: Sources, bioavailability, interaction with gut microbiota, and their impacts on human health
Kan J, Wu F, Wang F, Zheng J, Cheng J, Li Y, Yang Y, Du J |
Frontiers in Nutrition | 2022 |
Metabolic protection by the dietary flavonoid 7,8-dihydroxyflavone requires an intact gut microbiome
Sharma P, Silva C, Pfreundschuh S, Ye H, Sampath H |
Frontiers in Nutrition | 2022 |
The potential impact of a probiotic: Akkermansia muciniphila in the regulation of blood pressure—the current facts and evidence
Lakshmanan AP, Murugesan S, Al Khodor S, Terranegra A |
Journal of Translational Medicine | 2022 |
Regulation of CYP450 and drug transporter mediated by gut microbiota under high-altitude hypoxia
Bai X, Yang J, Liu G, Zhu J, Wang Q, Gu W, La L, Li X |
Frontiers in pharmacology | 2022 |
Methods and criteria for validating the multimodal functions of perinatal derivatives when used in oncological and antimicrobial applications.
Silini AR, Ramuta TŽ, Pires AS, Banerjee A, Dubus M, Gindraux F, Kerdjoudj H, Maciulatis J, Weidinger A, Wolbank S, Eissner G, Giebel B, Pozzobon M, Parolini O, Kreft ME |
Frontiers in Bioengineering and Biotechnology | 2022 |
Alteration of Oral Microbiome Composition in Children Living with Pesticide-Exposed Farm Workers
Stanaway IB, Wallace JC, Hong S, Wilder CS, Green FH, Tsai J, Knight M, Workman T, Vigoren EM, Smith MN, Griffith WC, Thompson B, Shojaie A, Faustman EM |
International Journal of Hygiene and Environmental Health | 2022 |
The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice
SA Barretto, F Lasserre, M Huillet, M Régnier, A Polizzi, Y Lippi, A Fougerat, E Person, S Bruel, C Bétoulières, C Naylies, C Lukowicz, S Smati, L Guzylack, M Olier, V Théodorou, L Mselli-Lakhal, D Zalko, W Wahli, N Loiseau, L Gamet-Payrastre, H Guillou, S Ellero-Simatos |
Microbiome | 2021 |
Structural diversity, functional aspects and future therapeutic applications of human gut microbiome
S Ghosh, S Pramanik |
Archives of Microbiology | 2021 |
Microbiome Metabolites and Thyroid Dysfunction
P Bargiel, M Szczuko, L Stachowska, P Prowans, N Czapla, M Markowska, J Petriczko, J Kledzik, A Jędrzejczyk-Kledzik, J Palma, P Zabielska, D Maciejewska-Markiewicz |
Journal of Clinical Medicine | 2021 |
Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications
S Nagar, UA Argikar, D Tweedie |
2021 | |
Sex- and Gender-Based Pharmacological Response to Drugs
F Mauvais-Jarvis, HK Berthold, I Campesi, JJ Carrero, S Dhakal, F Franconi, I Gouni-Berthold, ML Heiman, A Kautzky-Willer, SL Klein, A Murphy, V Regitz-Zagrosek, K Reue, JB Rubin, E Barker |
Pharmacological reviews | 2021 |
Can manipulation of gut microbiota really be transformed into an intervention strategy for cardiovascular disease management?
K Mehmood, A Moin, T Hussain, SM Rizvi, DV Gowda, S Shakil, MA Kamal |
Folia Microbiologica | 2021 |
Gut-Liver Immune Traffic: Deciphering Immune-Pathogenesis to Underpin Translational Therapy
AG Bozward, V Ronca, D Osei-Bordom, YH Oo |
Frontiers in immunology | 2021 |
Microbiota and Drug Response in Inflammatory Bowel Disease
M Franzin, K Stefančič, M Lucafò, G Decorti, G Stocco |
Pathogens | 2021 |
Interactions between maternal fluoxetine exposure, the maternal gut microbiome and fetal neurodevelopment in mice
HE Vuong, EJ Coley, M Kazantsev, ME Cooke, TK Rendon, J Paramo, EY Hsiao |
Behavioural Brain Research | 2021 |
The Role of Polyphenols in Regulation of Heat Shock Proteins and Gut Microbiota in Weaning Stress
T Hussain, J Wang, G Murtaza, E Metwally, H Yang, MS Kalhoro, DH Kalhoro, BA Rahu, B Tan, RG Sahito, MI Chughtai, Y Yin, AA Farooqi |
Oxidative Medicine & Cellular Longevity | 2021 |
Fecal Metabolic Profiling of Breast Cancer Patients during Neoadjuvant Chemotherapy Reveals Potential Biomarkers
O Zidi, N Souai, H Raies, FB Ayed, A Mezlini, S Mezrioui, F Tranchida, JM Sabatier, A Mosbah, A Cherif, L Shintu, S Kouidhi |
Molecules (Basel, Switzerland) | 2021 |
The microbiome: A heritable contributor to bone morphology?
C Hernandez, A Moeller |
Seminars in Cell & Developmental Biology | 2021 |
Entropy-driven binding of gut bacterial β-glucuronidase inhibitors ameliorates irinotecan-induced toxicity.
Lin HY, Chen CY, Lin TC, Yeh LF, Hsieh WC, Gao S, Burnouf PA, Chen BM, Hsieh TJ, Dashnyam P, Kuo YH, Tu Z, Roffler SR, Lin CH |
2021 | |
The gut microbiome influences the bioavailability of olanzapine in rats.
Cussotto S, Walsh J, Golubeva AV, Zhdanov AV, Strain CR, Fouhy F, Stanton C, Dinan TG, Hyland NP, Clarke G, Cryan JF, Griffin BT |
EBioMedicine | 2021 |
A framework for microbiome science in public health.
Wilkinson JE, Franzosa EA, Everett C, Li C, Hu FB, Wirth DF, Song M, Chan AT, Rimm E, Garrett WS, Huttenhower C |
Nature Medicine | 2021 |
Gastroprotective Effects of Polyphenols against Various Gastro-Intestinal Disorders: A Mini-Review with Special Focus on Clinical Evidence.
Chiu HF, Venkatakrishnan K, Golovinskaia O, Wang CK |
Molecules (Basel, Switzerland) | 2021 |
Next Generation Probiotics for Neutralizing Obesogenic Effects: Taxa Culturing Searching Strategies.
López-Moreno A, Acuña I, Torres-Sánchez A, Ruiz-Moreno Á, Cerk K, Rivas A, Suárez A, Monteoliva-Sánchez M, Aguilera M |
Nutrients | 2021 |
An integrated host-microbiome response to atrazine exposure mediates toxicity in Drosophila.
Brown JB, Langley SA, Snijders AM, Wan KH, Morris SNS, Booth BW, Fisher WW, Hammonds AS, Park S, Weiszmann R, Yu C, Kirwan JA, Weber RJM, Viant MR, Mao JH, Celniker SE |
2021 | |
Bioactive (Poly)phenols, Volatile Compounds from Vegetables, Medicinal and Aromatic Plants
Pinto T, Aires A, Cosme F, Bacelar E, Morais MC, Oliveira I, Ferreira-Cardoso J, Anjos R, Vilela A, Gonçalves B |
Foods | 2021 |
Gut microbial dysbiosis and its association with esophageal cancer.
Ishaq HM, Mohammad IS, Sher Muhammad K, Li H, Abbas RZ, Din Sindhu ZU, Ullah S, Fan Y, Sadiq A, Raza MA, Hussain R, Arshad HM, Khan I, Waqas MU, Ul-Rahman A, Yasin R, Rehman A, Akhtar RW, Xu J |
Journal of Applied Biomedicine | 2021 |
Curcumin, Quercetin, Catechins and Metabolic Diseases: The Role of Gut Microbiota.
Shabbir U, Rubab M, Daliri EB, Chelliah R, Javed A, Oh DH |
Nutrients | 2021 |
Tumor Profiling at the Service of Cancer Therapy.
Fernandez-Rozadilla C, Simões AR, Lleonart ME, Carnero A, Carracedo Á |
Frontiers in Oncology | 2021 |
The Bacterial Microbiota of Gastrointestinal Cancers: Role in Cancer Pathogenesis and Therapeutic Perspectives L Elsalem, AA Jum'ah, MA Alfaqih, O Aloudat |
Clinical and experimental gastroenterology | 2020 |
The dichotomous role of the gut microbiome in exacerbating and ameliorating neurodegenerative disorders
U Raval, JM Harary, E Zeng, GM Pasinetti |
Expert Review of Neurotherapeutics | 2020 |
Engineering Microphysiological Immune System Responses on Chips
CP Miller, W Shin, EH Ahn, HJ Kim, DH Kim |
Trends in Biotechnology | 2020 |
Is Extra Virgin Olive Oil an Ally for Women’s and Men’s Cardiovascular Health?
F Franconi, I Campesi, A Romani |
Cardiovascular Therapeutics | 2020 |
A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats
MP Letertre, N Munjoma, K Wolfer, A Pechlivanis, JA McDonald, RN Hardwick, NJ Cherrington, M Coen, JK Nicholson, L Hoyles, JR Swann, ID Wilson |
Journal of Proteome Research | 2020 |
Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host
A Chávez-Carbajal, ML Pizano-Zárate, F Hernández-Quiroz, GF Ortiz-Luna, RM Morales-Hernández, AD Sales-Millán, M Hernández-Trejo, A García-Vite, L Beltrán-Lagunes, C Hoyo-Vadillo, J García-Mena |
Microorganisms | 2020 |
Interaction between Gut Microbiota and Curcumin: A New Key of Understanding for the Health Effects of Curcumin
B Scazzocchio, L Minghetti, M DArchivio |
Nutrients | 2020 |
Environmental Endocrine-Disrupting Chemical Exposure: Role in Non-Communicable Diseases
M Kumar, DK Sarma, S Shubham, M Kumawat, V Verma, A Prakash, R Tiwari |
Frontiers in public health | 2020 |
Systemically-delivered biodegradable PLGA alters gut microbiota and induces transcriptomic reprogramming in the liver in an obesity mouse model
A Chaplin, H Gao, C Asase, P Rengasamy, B Park, D Skander, G Bebek, S Rajagopalan, A Maiseyeu |
Scientific Reports | 2020 |
Deconstructing Mechanisms of Diet-Microbiome-Immune Interactions
M Alexander, PJ Turnbaugh |
Immunity | 2020 |
Relationship Between the Gut Microbiome and Systemic Chemotherapy.
Ervin SM, Ramanan SV, Bhatt AP |
Digestive Diseases and Sciences | 2020 |
Comparison of Gut Microbiota Between Golden and Brown Noble Scallop Chlamys nobilis and Its Association With Carotenoids.
Liu H, Tan KS, Zhang X, Zhang H, Cheng D, Ting Y, Li S, Ma H, Zheng H |
Frontiers in microbiology | 2020 |
Manipulation of the Gut Microbiome Alters Acetaminophen Biodisposition in Mice.
Malfatti MA, Kuhn EA, Murugesh DK, Mendez ME, Hum N, Thissen JB, Jaing CJ, Loots GG |
Scientific Reports | 2020 |
Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics.
Abdelsalam NA, Ramadan AT, ElRakaiby MT, Aziz RK |
Frontiers in pharmacology | 2020 |
Targeting gut microbiota for precision medicine: Focusing on the efficacy and toxicity of drugs
Feng W, Liu J, Ao H, Yue S, Peng C |
Theranostics | 2020 |
Virome Sequencing of the Human Intestinal Mucosal–Luminal Interface
Yan A, Butcher J, Mack D, Stintzi A |
Frontiers in Cellular and Infection Microbiology | 2020 |
New planar assay for streamlined detection and quantification of β-glucuronidase inhibitors applied to botanical extracts.
Mahran E, Keusgen M, Morlock GE |
2020 | |
Curcumin and Its Derivatives as Theranostic Agents in Alzheimer's Disease: The Implication of Nanotechnology.
Shabbir U, Rubab M, Tyagi A, Oh DH |
International journal of molecular sciences | 2020 |
Circulating glucuronic acid predicts healthspan and longevity in humans and mice
A Ho, J Sinick, T Esko, K Fischer, C Menni, J Zierer, M Matey-Hernandez, K Fortney, EK Morgen |
Aging | 2019 |
The gut microbiome in tuberculosis susceptibility and treatment response: guilty or not guilty?
OA Eribo, N du Plessis, M Ozturk, R Guler, G Walzl, NN Chegou |
Cellular and Molecular Life Sciences | 2019 |
The genital tract and rectal microbiomes: their role in HIV susceptibility and prevention in women
SS Karim, C Baxter, JA Passmore, LR McKinnon, BL Williams |
Journal of the International AIDS Society | 2019 |
Mechanisms of gastrointestinal microflora on drug metabolism in clinical practice
C Sun, L Chen, Z Shen |
Saudi Pharmaceutical Journal | 2019 |
BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification
Y Djoumbou-Feunang, J Fiamoncini, A Gil-de-la-Fuente, R Greiner, C Manach, DS Wishart |
Journal of cheminformatics | 2019 |
Nutritional Intervention for the Intestinal Development and Health of Weaned Pigs
X Xiong, B Tan, M Song, P Ji, K Kim, Y Yin, Y Liu |
Frontiers in Veterinary Science | 2019 |
Polyphenolic Nutraceuticals to Combat Oxidative Stress Through Microbiota Modulation
E Vamanu |
Frontiers in pharmacology | 2019 |
Gut Microbiota Shifts in Pup Athymic BALB/c Mice: An Updated Identification in Nude Mice
Y Li, H Sun, B Du, H Xu |
Animals | 2019 |
Xenobiotics Formed during Food Processing: Their Relation with the Intestinal Microbiota and Colorectal Cancer
AM Nogacka, M Gómez-Martín, A Suárez, O González-Bernardo, CG de los Reyes-Gavilán, S González |
International journal of molecular sciences | 2019 |
Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation
VM Koistinen, O Kärkkäinen, K Borewicz, I Zarei, J Jokkala, V Micard, N Rosa-Sibakov, S Auriola, AM Aura, H Smidt, K Hanhineva |
Microbiome | 2019 |
Gut Microbiome and Response to Cardiovascular Drugs
S Tuteja, JF Ferguson |
Circulation. Genomic and precision medicine | 2019 |
Gut microbiome: An intermediary to neurotoxicity
JL Dempsey, M Little, JY Cui |
NeuroToxicology | 2019 |
Advancing functional and translational microbiome research using meta-omics approaches
X Zhang, L Li, J Butcher, A Stintzi, D Figeys |
Microbiome | 2019 |
Effects of Atypical Antipsychotic Treatment and Resistant Starch Supplementation on Gut Microbiome Composition in a Cohort of Patients with Bipolar Disorder or Schizophrenia.
Flowers SA, Baxter NT, Ward KM, Kraal AZ, McInnis MG, Schmidt TM, Ellingrod VL |
Pharmacotherapy | 2019 |
Curcumin, Gut Microbiota, and Neuroprotection.
Di Meo F, Margarucci S, Galderisi U, Crispi S, Peluso G |
Nutrients | 2019 |
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria.
Bess EN, Bisanz JE, Yarza F, Bustion A, Rich BE, Li X, Kitamura S, Waligurski E, Ang QY, Alba DL, Spanogiannopoulos P, Nayfach S, Koliwad SK, Wolan DW, Franke AA, Turnbaugh PJ |
Nature Microbiology | 2019 |
From the Bottom-Up: Chemotherapy and Gut-Brain Axis Dysregulation
JE Bajic, IN Johnston, GS Howarth, MR Hutchinson |
Frontiers in behavioral neuroscience | 2018 |
Making Millennial Medicine More Meta
PJ Turnbaugh |
mSystems | 2018 |
The importance of the microbiome in pediatrics and pediatric infectious diseases:
T Gaufin, NH Tobin, GM Aldrovandi |
Current Opinion in Pediatrics | 2018 |
Conducting metagenomic studies in microbiology and clinical research
TC Martin, A Visconti, TD Spector, M Falchi |
Applied Microbiology and Biotechnology | 2018 |
The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism
BD Weger, C Gobet, J Yeung, E Martin, S Jimenez, B Betrisey, F Foata, B Berger, A Balvay, A Foussier, A Charpagne, B Boizet-Bonhoure, CJ Chou, F Naef, F Gachon |
Cell Metabolism | 2018 |
Polyphenols-gut microbiota interplay and brain neuromodulation
S Filosa, FD Meo, S Crispi |
NEURAL REGEN RES | 2018 |
Thinking Outside the Cereal Box: Noncarbohydrate Routes for Dietary Manipulation of the Gut Microbiota
AT Reese, RN Carmody, EV Stabb |
Applied and environmental microbiology | 2018 |
Pharmacological Efficacy/Toxicity of Drugs: A Comprehensive Update About the Dynamic Interplay of Microbes
JA Gimenez-Bastida, LM Carreras, A Moya-Pérez, JM Llopis |
Journal of Pharmaceutical Sciences | 2018 |
The impact of exercise training and resveratrol supplementation on gut microbiota composition in high‐fat diet fed mice
Brandt N, Kotowska D, Kristensen CM, Olesen J, Lützhøft DO, Halling JF, Hansen M, Al\u2010Soud WA, Hansen L, Kiilerich P, Pilegaard H |
Physiological Reports | 2018 |
Tetz’s theory and law of longevity
Tetz G, Tetz V |
Theory in Biosciences | 2018 |
β-Glucuronidases of opportunistic bacteria are the major contributors to xenobiotic-induced toxicity in the gut
Dashnyam P, Mudududdla R, Hsieh TJ, Lin TC, Lin HY, Chen PY, Hsu CY, Lin CH |
Scientific Reports | 2018 |
Gut Microbiota Modulates Interactions Between Polychlorinated Biphenyls and Bile Acid Homeostasis
Cheng SL, Li X, Lehmler HJ, Phillips B, Shen D, Cui JY |
Toxicological Sciences | 2018 |
A Probe-Enabled Approach for the Selective Isolation and Characterization of Functionally Active Subpopulations in the Gut Microbiome
Whidbey C, Sadler NC, Nair RN, Volk RF, DeLeon AJ, Bramer LM, Fansler SJ, Hansen JR, Shukla AK, Jansson JK, Thrall BD, Wright AT |
Journal of the American Chemical Society | 2018 |
Anticancer effects of the microbiome and its products
L Zitvogel, R Daillère, MP Roberti, B Routy, G Kroemer |
Nature Reviews Microbiology | 2017 |
Gut microbiome as a clinical tool in gastrointestinal disease management: are we there yet?
EM Quigley |
Nature Reviews Gastroenterology & Hepatology | 2017 |
Microbiota-Brain-Gut Axis and Neurodegenerative Diseases
EM Quigley |
Current Neurology and Neuroscience Reports | 2017 |
The Opportunities of Metabolomics in Drug Safety Evaluation
P Wang, AI Shehu, X Ma |
Current Pharmacology Reports | 2017 |
Mining the Human Gut Microbiota for Immunomodulatory Organisms
N Geva-Zatorsky, E Sefik, L Kua, L Pasman, TG Tan, A Ortiz-Lopez, TB Yanortsang, L Yang, R Jupp, D Mathis, C Benoist, DL Kasper |
Cell | 2017 |
Microbial metabolites in health and disease: Navigating the unknown in search of function
KB Martinez, V Leone, EB Chang |
The Journal of biological chemistry | 2017 |
Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals
MC Theilmann, YJ Goh, KF Nielsen, TR Klaenhammer, R Barrangou, MA Hachem, E Martens, MJ McFall-Ngai |
mBio | 2017 |
Review of the gut microbiome and esophageal cancer: Pathogenesis and potential clinical implications.
Baba Y, Iwatsuki M, Yoshida N, Watanabe M, Baba H |
Annals of Gastroenterological Surgery | 2017 |
Insights into human evolution from ancient and contemporary microbiome studies
SL Schnorr, K Sankaranarayanan, CM Lewis, C Warinner |
Current Opinion in Genetics & Development | 2016 |
Signaling in Host-Associated Microbial Communities
MA Fischbach, JA Segre |
Cell | 2016 |
Longitudinal Prediction of the Infant Gut Microbiome with Dynamic Bayesian Networks
MJ McGeachie, JE Sordillo, T Gibson, GM Weinstock, YY Liu, DR Gold, ST Weiss, A Litonjua |
Scientific Reports | 2016 |
The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism
P Spanogiannopoulos, EN Bess, RN Carmody, PJ Turnbaugh |
Nature Reviews Microbiology | 2016 |
Gut microbiome interactions with drug metabolism, efficacy, and toxicity
ID Wilson, JK Nicholson |
Translational Research | 2016 |
Chronic Rhinosinusitis and the Evolving Understanding of Microbial Ecology in Chronic Inflammatory Mucosal Disease
M Hoggard, BW Mackenzie, R Jain, MW Taylor, K Biswas, RG Douglas |
Clinical microbiology reviews | 2016 |
Human Oral Buccal Microbiomes Are Associated with Farmworker Status and Azinphos-Methyl Agricultural Pesticide Exposure
IB Stanaway, JC Wallace, A Shojaie, WC Griffith, S Hong, CS Wilder, FH Green, J Tsai, M Knight, T Workman, EM Vigoren, JS McLean, B Thompson, EM Faustman, HL Drake |
Applied and environmental microbiology | 2016 |
Dietary Chitosan Supplementation Increases Microbial Diversity and Attenuates the Severity of Citrobacter rodentium Infection in Mice
G Guan, H Wang, S Chen, G Liu, X Xiong, B Tan, V Duraipandiyan, NA Al-Dhabi, J Fang |
Mediators of Inflammation | 2016 |
Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity.
Wu JC, Lai CS, Tsai ML, Ho CT, Wang YJ, Pan MH |
Journal of Food and Drug Analysis | 2016 |
Nutritional Modulation of Gut Microbiota - The Impact on Metabolic Disease Pathophysiology
P Ojeda, A Bobe, K Dolan, V Leone, K Martinez |
The Journal of Nutritional Biochemistry | 2015 |
Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism
R Dheer, J Patterson, M Dudash, EN Stachler, KJ Bibby, DB Stolz, S Shiva, Z Wang, SL Hazen, A Barchowsky, JF Stolz |
Toxicology and Applied Pharmacology | 2015 |
Cancer and the microbiota
WS Garrett |
Science | 2015 |
Potential for using a hermetically-sealed, positive-pressured isocage system for studies involving germ-free mice outside a flexible-film isolator
J Paik, O Pershutkina, S Meeker, JJ Yi, S Dowling, C Hsu, AM Hajjar, L Maggio-Price, DA Beck |
Gut microbes | 2015 |
Mouse Models as Predictors of Human Responses: Evolutionary Medicine
EW Uhl, NJ Warner |
Current Pathobiology Reports | 2015 |
Challenges Associated with Route of Administration in Neonatal Drug Delivery
MW Linakis, JK Roberts, AC Lala, MG Spigarelli, NJ Medlicott, DM Reith, RM Ward, CM Sherwin |
Clinical Pharmacokinetics | 2015 |
Editorial on "Cancer and the microbiota" published in Science
Alison K Hamm, Tiffany L Weir |
Annals of translational medicine | 2015 |
Drug Metabolism by the Host and Gut Microbiota: A Partnership or Rivalry?
HI Swanson |
Drug metabolism and disposition: the biological fate of chemicals | 2015 |
Gut Microbiome: What We Do and Dont Know
GA Cresci, E Bawden |
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition | 2015 |
The microbiome revolution
Martin J. Blaser |
Journal of Clinical Investigation | 2014 |
Microbial Determinants of Biochemical Individuality and Their Impact on Toxicology and Pharmacology
AD Patterson, PJ Turnbaugh |
Cell Metabolism | 2014 |